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Term:bretylium tosylate
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Accession:CHEBI:3173 term browser browse the term
Definition:The tosylate salt of bretylium. It blocks noradrenaline release from the peripheral sympathetic nervous system, and is used in emergency medicine, cardiology, and other specialties for the acute management of ventricular tachycardia and ventricular fibrillation.
Synonyms:exact_synonym: N-(2-bromobenzyl)-N,N-dimethylethanaminium 4-methylbenzenesulfonate
 related_synonym: (2-bromobenzyl)ethyldimethylammonium toluene-4-sulfonate;   (2-bromobenzyl)ethyldimethylammonium tosylate;   (o-bromobenzyl)ethyldimethylammonium p-toluenesulfonate;   2-bromo-N-ethyl-N,N-dimethylbenzenemethanaminium 4-methylbenzenesulfonate;   Formula=C18H24BrNO3S;   InChI=1S/C11H17BrN.C7H8O3S/c1-4-13(2,3)9-10-7-5-6-8-11(10)12;1-6-2-4-7(5-3-6)11(8,9)10/h5-8H,4,9H2,1-3H3;2-5H,1H3,(H,8,9,10)/q+1;/p-1;   InChIKey=KVWNWTZZBKCOPM-UHFFFAOYSA-M;   N-ethyl-N-o-bromobenzyl-N,N-dimethylammonium tosylate;   SMILES=Cc1ccc(cc1)S([O-])(=O)=O.CC[N+](C)(C)Cc1ccccc1Br;   bretylii tosilas;   dimethylethyl-o-bromobenzylammonium-p-toluenesulphonate;   tosilate de bretylium;   tosilato de bretilio
 xref: Beilstein:5702258 "Beilstein";   CAS:61-75-6 "ChemIDplus";   DrugBank:DB01158;   KEGG:D00645
 xref_mesh: MESH:D001950
 xref: Patent:US3038004

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bretylium tosylate term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Slc22a2 solute carrier family 22 member 2 JBrowse link 1 48,318,025 48,360,219 RGD:6480464

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  CHEBI ontology 19669
    role 19613
      application 19235
        pharmaceutical 19097
          drug 19097
            cardiovascular drug 7550
              antihypertensive agent 1637
                bretylium tosylate 1
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  CHEBI ontology 19669
    subatomic particle 19665
      composite particle 19665
        hadron 19665
          baryon 19665
            nucleon 19665
              atomic nucleus 19665
                atom 19665
                  main group element atom 19545
                    main group molecular entity 19545
                      s-block molecular entity 19329
                        hydrogen molecular entity 19319
                          hydrides 18242
                            inorganic hydride 17104
                              pnictogen hydride 17062
                                nitrogen hydride 16885
                                  ammonium 8204
                                    ammonium ion derivative 8199
                                      ammonium compound 5076
                                        organoammonium salt 404
                                          quaternary ammonium salt 286
                                            bretylium tosylate 1
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