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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:lucanthone
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Accession:CHEBI:51052 term browser browse the term
Definition:A thioxanthen-9-one compound having a methyl substituent at the 1-position and a 2-[(diethylamino)ethyl]amino substituent at the 4-position. Formerly used for the treatment of schistosomiasis. It is a prodrug, being metabolised to hycanthone.
Synonyms:exact_synonym: 1-{[2-(diethylamino)ethyl]amino}-4-methyl-9H-thioxanthen-9-one
 related_synonym: 1-diethylaminoethylethylamino-4-methyl-thioxanthenone;   1-{[2-(diethylamino)ethyl]amino}-4-methylthioxanthen-9-one;   Formula=C20H24N2OS;   InChI=1S/C20H24N2OS/c1-4-22(5-2)13-12-21-16-11-10-14(3)20-18(16)19(23)15-8-6-7-9-17(15)24-20/h6-11,21H,4-5,12-13H2,1-3H3;   InChIKey=FBQPGGIHOFZRGH-UHFFFAOYSA-N;   SMILES=CCN(CC)CCNc1ccc(C)c2sc3ccccc3c(=O)c12;   lucanthonum;   lucantona
 alt_id: CHEBI:19039;   CHEBI:6552
 xref: CAS:479-50-5;   DrugBank:DB04967;   Drug_Central:1616;   HMDB:HMDB0015607;   KEGG:C11715
 xref_mesh: MESH:D008154
 xref: PMID:21148553;   PMID:21935361;   PMID:4368942;   PMID:6887199;   PMID:9169823;   Reaxys:312369;   Wikipedia:Lucanthone



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lucanthone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca12 ATP binding cassette subfamily A member 12 increases expression ISO Lucanthone results in increased expression of ABCA12 mRNA CTD PMID:21148553 NCBI chr 9:80,272,121...80,445,340
Ensembl chr 9:80,272,127...80,445,340
JBrowse link
G Acta2 actin alpha 2, smooth muscle increases expression ISO Lucanthone results in increased expression of ACTA2 mRNA CTD PMID:21148553 NCBI chr 1:241,159,723...241,172,503
Ensembl chr 1:241,159,724...241,172,503
JBrowse link
G Aldh1l2 aldehyde dehydrogenase 1 family, member L2 decreases expression ISO Lucanthone results in decreased expression of ALDH1L2 mRNA CTD PMID:21148553 NCBI chr 7:22,141,872...22,193,403
Ensembl chr 7:22,141,842...22,193,398
JBrowse link
G Anln anillin, actin binding protein decreases expression ISO Lucanthone results in decreased expression of ANLN mRNA CTD PMID:21148553 NCBI chr 8:29,134,222...29,197,513
Ensembl chr 8:29,134,222...29,197,513
JBrowse link
G Anxa3 annexin A3 decreases expression ISO Lucanthone results in decreased expression of ANXA3 mRNA CTD PMID:21148553 NCBI chr14:13,031,675...13,085,678
Ensembl chr14:13,023,762...13,085,849
JBrowse link
G Aqp3 aquaporin 3 (Gill blood group) increases expression ISO Lucanthone results in increased expression of AQP3 mRNA CTD PMID:21148553 NCBI chr 5:61,035,165...61,040,683
Ensembl chr 5:61,035,166...61,040,685
JBrowse link
G Arhgap11a Rho GTPase activating protein 11A decreases expression ISO Lucanthone results in decreased expression of ARHGAP11A mRNA CTD PMID:21148553 NCBI chr 3:121,045,187...121,071,985
Ensembl chr 3:121,045,187...121,061,468
JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) decreases expression ISO Lucanthone results in decreased expression of ASNS mRNA CTD PMID:21148553 NCBI chr 4:36,752,061...36,769,970
Ensembl chr 4:36,751,802...36,776,050
JBrowse link
G Aspm assembly factor for spindle microtubules decreases expression ISO Lucanthone results in decreased expression of ASPM mRNA CTD PMID:21148553 NCBI chr13:53,625,584...53,674,489
Ensembl chr13:53,625,584...53,674,489
JBrowse link
G Atad2 ATPase family, AAA domain containing 2 decreases expression ISO Lucanthone results in decreased expression of ATAD2 mRNA CTD PMID:21148553 NCBI chr 7:91,523,626...91,566,238
Ensembl chr 7:91,523,626...91,566,238
JBrowse link
G Aurka aurora kinase A decreases expression ISO Lucanthone results in decreased expression of AURKA mRNA CTD PMID:21148553 NCBI chr 3:181,546,742...181,562,890
Ensembl chr 3:181,546,742...181,562,771
JBrowse link
G Aurkb aurora kinase B decreases expression ISO Lucanthone results in decreased expression of AURKB mRNA CTD PMID:21148553 NCBI chr10:54,243,116...54,249,675
Ensembl chr10:54,242,850...54,252,285
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 decreases expression ISO Lucanthone results in decreased expression of BIRC5 mRNA CTD PMID:21148553 NCBI chr10:103,567,369...103,580,069
Ensembl chr10:103,572,080...103,582,155
JBrowse link
G Blm BLM RecQ like helicase decreases expression ISO Lucanthone results in decreased expression of BLM mRNA CTD PMID:21148553 NCBI chr 1:143,819,072...143,905,300
Ensembl chr 1:143,819,090...143,905,210
JBrowse link
G Brca1 BRCA1, DNA repair associated decreases expression ISO Lucanthone results in decreased expression of BRCA1 mRNA CTD PMID:21148553 NCBI chr10:86,917,693...86,978,012
Ensembl chr10:86,917,693...86,977,763
JBrowse link
G Brca2 BRCA2, DNA repair associated decreases expression ISO Lucanthone results in decreased expression of BRCA2 mRNA CTD PMID:21148553 NCBI chr12:4,895,092...4,939,340
Ensembl chr12:4,895,447...4,936,194
JBrowse link
G Bub1 BUB1 mitotic checkpoint serine/threonine kinase decreases expression ISO Lucanthone results in decreased expression of BUB1 mRNA CTD PMID:21148553 NCBI chr 3:135,473,525...135,504,921
Ensembl chr 3:135,472,582...135,504,921
JBrowse link
G Bub1b BUB1 mitotic checkpoint serine/threonine kinase B decreases expression ISO Lucanthone results in decreased expression of BUB1B mRNA CTD PMID:21148553 NCBI chr 3:126,017,019...126,069,470
Ensembl chr 3:126,017,045...126,069,796
JBrowse link
G C2h5orf34 similar to human chromosome 5 open reading frame 34 decreases expression ISO Lucanthone results in decreased expression of C5ORF34 mRNA CTD PMID:21148553 NCBI chr 2:53,287,353...53,309,804
Ensembl chr 2:53,287,957...53,309,806
JBrowse link
G Ccn3 cellular communication network factor 3 increases expression ISO Lucanthone results in increased expression of CCN3 mRNA CTD PMID:21148553 NCBI chr 7:87,983,788...87,990,810
Ensembl chr 7:87,982,216...87,994,581
JBrowse link
G Ccna2 cyclin A2 decreases expression ISO Lucanthone results in decreased expression of CCNA2 mRNA CTD PMID:21148553 NCBI chr 2:121,355,363...121,361,762
Ensembl chr 2:121,355,363...121,361,701
JBrowse link
G Ccnb1 cyclin B1 decreases expression ISO Lucanthone results in decreased expression of CCNB1 mRNA CTD PMID:21148553 NCBI chr 2:33,646,252...33,655,225
Ensembl chr 2:33,646,252...33,655,225
JBrowse link
G Ccnb2 cyclin B2 decreases expression ISO Lucanthone results in decreased expression of CCNB2 mRNA CTD PMID:21148553 NCBI chr 8:79,968,459...79,981,717
Ensembl chr 8:79,968,465...79,981,682
JBrowse link
G Cdc20 cell division cycle 20 decreases expression ISO Lucanthone results in decreased expression of CDC20 mRNA CTD PMID:21148553 NCBI chr 5:137,251,596...137,255,799
Ensembl chr 5:137,251,596...137,255,799
JBrowse link
G Cdc25c cell division cycle 25C decreases expression ISO Lucanthone results in decreased expression of CDC25C mRNA CTD PMID:21148553 NCBI chr18:26,608,483...26,630,292
Ensembl chr18:26,609,959...26,630,292
JBrowse link
G Cdc45 cell division cycle 45 decreases expression ISO Lucanthone results in decreased expression of CDC45 mRNA CTD PMID:21148553 NCBI chr11:95,689,702...95,714,980
Ensembl chr11:95,689,919...95,714,981
JBrowse link
G Cdc6 cell division cycle 6 decreases expression ISO Lucanthone results in decreased expression of CDC6 mRNA CTD PMID:21148553 NCBI chr10:84,360,361...84,374,239
Ensembl chr10:84,360,381...84,374,241
JBrowse link
G Cdca2 cell division cycle associated 2 decreases expression ISO Lucanthone results in decreased expression of CDCA2 mRNA CTD PMID:21148553 NCBI chr15:46,071,360...46,117,524
Ensembl chr15:46,071,360...46,116,639
JBrowse link
G Cdk1 cyclin-dependent kinase 1 decreases expression ISO Lucanthone results in decreased expression of CDK1 mRNA CTD PMID:21148553 NCBI chr20:19,265,252...19,280,456
Ensembl chr20:19,265,289...19,280,455
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO Lucanthone results in increased expression of CDKN1A mRNA CTD PMID:21148553 NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969
JBrowse link
G Cdkn3 cyclin-dependent kinase inhibitor 3 decreases expression ISO Lucanthone results in decreased expression of CDKN3 mRNA CTD PMID:21148553 NCBI chr15:22,502,299...22,513,725
Ensembl chr15:22,502,382...22,513,722
JBrowse link
G Cenpa centromere protein A decreases expression ISO Lucanthone results in decreased expression of CENPA mRNA CTD PMID:21148553 NCBI chr 6:31,420,062...31,431,703 JBrowse link
G Cenpe centromere protein E decreases expression ISO Lucanthone results in decreased expression of CENPE mRNA CTD PMID:21148553 NCBI chr 2:226,310,970...226,369,636
Ensembl chr 2:226,300,798...226,369,636
JBrowse link
G Cenpf centromere protein F decreases expression ISO Lucanthone results in decreased expression of CENPF mRNA CTD PMID:21148553 NCBI chr13:103,715,344...103,760,931
Ensembl chr13:103,715,344...103,760,886
JBrowse link
G Cenpi centromere protein I decreases expression ISO Lucanthone results in decreased expression of CENPI mRNA CTD PMID:21148553 NCBI chr  X:101,809,192...101,860,935
Ensembl chr  X:101,809,659...101,860,934
JBrowse link
G Cenpk centromere protein K decreases expression ISO Lucanthone results in decreased expression of CENPK mRNA CTD PMID:21148553 NCBI chr 2:37,094,163...37,155,158
Ensembl chr 2:37,094,248...37,119,488
JBrowse link
G Cenpl centromere protein L decreases expression ISO Lucanthone results in decreased expression of CENPL mRNA CTD PMID:21148553 NCBI chr13:75,870,479...75,885,466
Ensembl chr13:75,870,489...75,905,250
JBrowse link
G Cenpu centromere protein U decreases expression ISO Lucanthone results in decreased expression of CENPU mRNA CTD PMID:21148553 NCBI chr16:52,448,446...52,471,662
Ensembl chr16:52,425,096...52,471,662
JBrowse link
G Cep55 centrosomal protein 55 decreases expression ISO Lucanthone results in decreased expression of CEP55 mRNA CTD PMID:21148553 NCBI chr 1:245,245,272...245,260,835
Ensembl chr 1:245,245,306...245,260,890
JBrowse link
G Cip2a cellular inhibitor of PP2A decreases expression ISO Lucanthone results in decreased expression of CIP2A mRNA CTD PMID:21148553 NCBI chr11:65,255,123...65,285,914
Ensembl chr11:65,255,123...65,285,914
JBrowse link
G Cit citron rho-interacting serine/threonine kinase decreases expression ISO Lucanthone results in decreased expression of CIT mRNA CTD PMID:21148553 NCBI chr12:46,263,881...46,425,642
Ensembl chr12:46,266,369...46,424,656
JBrowse link
G Ckap2l cytoskeleton associated protein 2-like decreases expression ISO Lucanthone results in decreased expression of CKAP2L mRNA CTD PMID:21148553 NCBI chr 3:136,950,390...136,977,503
Ensembl chr 3:136,950,381...136,977,565
JBrowse link
G Cks1b CDC28 protein kinase regulatory subunit 1B decreases expression ISO Lucanthone results in decreased expression of CKS1B mRNA CTD PMID:21148553 NCBI chr 2:177,130,751...177,135,333
Ensembl chr 2:177,130,777...177,135,365
JBrowse link
G Clca2 chloride channel accessory 2 increases expression ISO Lucanthone results in increased expression of CLCA2 mRNA CTD PMID:21148553 NCBI chr 2:236,655,419...236,682,669
Ensembl chr 2:236,639,545...236,685,129
JBrowse link
G Cldn1 claudin 1 decreases expression ISO Lucanthone results in decreased expression of CLDN1 mRNA CTD PMID:21148553 NCBI chr11:87,926,376...87,941,533
Ensembl chr11:87,926,337...87,941,529
JBrowse link
G Clgn calmegin decreases expression ISO Lucanthone results in decreased expression of CLGN mRNA CTD PMID:21148553 NCBI chr19:41,601,568...41,633,207
Ensembl chr19:41,601,568...41,633,325
JBrowse link
G Cmklr2 chemerin chemokine-like receptor 2 decreases expression ISO Lucanthone results in decreased expression of CMKLR2 mRNA CTD PMID:21148553 NCBI chr 9:72,077,164...72,111,979
Ensembl chr 9:72,078,608...72,116,257
JBrowse link
G Ctsd cathepsin D increases expression ISO Lucanthone results in increased expression of CTSD mRNA; Lucanthone results in increased expression of CTSD protein CTD PMID:21148553 NCBI chr 1:206,956,945...206,968,821
Ensembl chr 1:206,956,944...206,968,821
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 increases expression ISO Lucanthone results in increased expression of CXCL10 mRNA CTD PMID:21148553 NCBI chr14:15,989,066...15,991,263
Ensembl chr14:15,989,018...15,991,261
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression ISO Lucanthone results in increased expression of CYP1A1 mRNA CTD PMID:21148553 NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 decreases expression ISO Lucanthone results in decreased expression of DDIT3 mRNA CTD PMID:21148553 NCBI chr 7:65,001,695...65,006,517
Ensembl chr 7:65,005,501...65,006,509
JBrowse link
G Depdc1 DEP domain containing 1 decreases expression ISO Lucanthone results in decreased expression of DEPDC1 mRNA CTD PMID:21148553 NCBI chr 2:251,343,250...251,376,709
Ensembl chr 2:251,343,281...251,376,709
JBrowse link
G Depdc1b DEP domain containing 1B decreases expression ISO Lucanthone results in decreased expression of DEPDC1B mRNA CTD PMID:21148553 NCBI chr 2:41,605,686...41,697,207
Ensembl chr 2:41,624,922...41,697,202
JBrowse link
G Dhcr24 24-dehydrocholesterol reductase increases expression ISO Lucanthone results in increased expression of DHCR24 mRNA CTD PMID:21148553 NCBI chr 5:126,573,366...126,599,940
Ensembl chr 5:126,573,338...126,599,936
JBrowse link
G Diaph3 diaphanous-related formin 3 decreases expression ISO Lucanthone results in decreased expression of DIAPH3 mRNA CTD PMID:21148553 NCBI chr15:68,951,992...69,421,623
Ensembl chr15:68,951,989...69,421,552
JBrowse link
G Dlgap5 DLG associated protein 5 decreases expression ISO Lucanthone results in decreased expression of DLGAP5 mRNA CTD PMID:21148553 NCBI chr15:23,113,678...23,144,281
Ensembl chr15:23,113,678...23,144,176
JBrowse link
G Dnai3 dynein axonemal intermediate chain 3 increases expression ISO Lucanthone results in increased expression of DNAI3 mRNA CTD PMID:21148553 NCBI chr 2:237,608,202...237,666,465
Ensembl chr 2:237,604,068...237,666,465
JBrowse link
G Dpp4 dipeptidylpeptidase 4 increases expression ISO Lucanthone results in increased expression of DPP4 mRNA CTD PMID:21148553 NCBI chr 3:67,370,794...67,452,422
Ensembl chr 3:67,370,804...67,452,422
JBrowse link
G Dtl denticleless E3 ubiquitin protein ligase homolog decreases expression ISO Lucanthone results in decreased expression of DTL mRNA CTD PMID:21148553 NCBI chr13:105,646,908...105,685,921
Ensembl chr13:105,646,908...105,686,174
JBrowse link
G Ect2 epithelial cell transforming 2 decreases expression ISO Lucanthone results in decreased expression of ECT2 mRNA CTD PMID:21148553 NCBI chr 2:111,904,522...111,966,786
Ensembl chr 2:111,904,522...111,966,626
JBrowse link
G Efemp1 EGF containing fibulin extracellular matrix protein 1 decreases expression ISO Lucanthone results in decreased expression of EFEMP1 mRNA CTD PMID:21148553 NCBI chr14:106,811,769...106,890,961
Ensembl chr14:106,802,304...106,892,808
JBrowse link
G Ercc6l ERCC excision repair 6 like, spindle assembly checkpoint helicase decreases expression ISO Lucanthone results in decreased expression of ERCC6L mRNA CTD PMID:21148553 NCBI chr  X:71,285,380...71,301,186
Ensembl chr  X:71,285,380...71,301,186
JBrowse link
G Esco2 establishment of sister chromatid cohesion N-acetyltransferase 2 decreases expression ISO Lucanthone results in decreased expression of ESCO2 mRNA CTD PMID:21148553 NCBI chr15:44,210,124...44,230,785
Ensembl chr15:44,210,641...44,231,304
Ensembl chr15:44,210,641...44,231,304
JBrowse link
G Espl1 extra spindle pole bodies like 1, separase decreases expression ISO Lucanthone results in decreased expression of ESPL1 mRNA CTD PMID:21148553 NCBI chr 7:135,302,460...135,329,570
Ensembl chr 7:135,302,716...135,329,570
JBrowse link
G Exo1 exonuclease 1 decreases expression ISO Lucanthone results in decreased expression of EXO1 mRNA CTD PMID:21148553 NCBI chr13:90,341,947...90,366,861
Ensembl chr13:90,342,018...90,366,861
JBrowse link
G Exosc8 exosome component 8 decreases expression ISO Lucanthone results in decreased expression of EXOSC8 mRNA CTD PMID:21148553 NCBI chr 2:141,080,568...141,087,112
Ensembl chr 2:141,080,568...141,087,229
JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit decreases expression ISO Lucanthone results in decreased expression of EZH2 mRNA CTD PMID:21148553 NCBI chr 4:77,624,223...77,698,598
Ensembl chr 4:77,624,223...77,687,183
JBrowse link
G Fam72a family with sequence similarity 72, member A decreases expression ISO Lucanthone results in decreased expression of FAM72A mRNA CTD PMID:21148553 NCBI chr13:45,519,940...45,531,322
Ensembl chr13:45,519,818...45,531,324
JBrowse link
G Fanci FA complementation group I decreases expression ISO Lucanthone results in decreased expression of FANCI mRNA CTD PMID:21148553 NCBI chr 1:142,736,636...142,792,999
Ensembl chr 1:142,736,653...142,792,999
JBrowse link
G Fbxo5 F-box protein 5 decreases expression ISO Lucanthone results in decreased expression of FBXO5 mRNA CTD PMID:21148553 NCBI chr 1:44,601,412...44,607,781
Ensembl chr 1:44,601,412...44,607,781
JBrowse link
G Flg filaggrin decreases expression ISO Lucanthone results in decreased expression of FLG mRNA CTD PMID:21148553 NCBI chr 2:181,583,801...181,596,464
Ensembl chr 2:181,583,808...181,595,968
JBrowse link
G Foxm1 forkhead box M1 decreases expression ISO Lucanthone results in decreased expression of FOXM1 mRNA CTD PMID:21148553 NCBI chr 4:163,325,628...163,338,100
Ensembl chr 4:163,325,614...163,337,172
JBrowse link
G Gbp1 guanylate binding protein 1 decreases expression ISO Lucanthone results in decreased expression of GBP1 mRNA CTD PMID:21148553 NCBI chr 2:234,071,366...234,106,012
Ensembl chr 2:234,190,708...234,206,802
Ensembl chr 2:234,190,708...234,206,802
JBrowse link
G Gdf15 growth differentiation factor 15 increases expression ISO Lucanthone results in increased expression of GDF15 mRNA CTD PMID:21148553 NCBI chr16:18,838,436...18,842,022
Ensembl chr16:18,838,436...18,842,022
JBrowse link
G Gpnmb glycoprotein nmb increases expression ISO Lucanthone results in increased expression of GPNMB mRNA CTD PMID:21148553 NCBI chr 4:79,341,128...79,362,366
Ensembl chr 4:79,341,021...79,380,240
JBrowse link
G Gpx8 glutathione peroxidase 8 decreases expression ISO Lucanthone results in decreased expression of GPX8 mRNA CTD PMID:21148553 NCBI chr 2:46,409,646...46,413,401
Ensembl chr 2:46,409,139...46,413,406
JBrowse link
G Gtpbp2 GTP binding protein 2 decreases expression ISO Lucanthone results in decreased expression of GTPBP2 mRNA CTD PMID:21148553 NCBI chr 9:22,311,532...22,321,405
Ensembl chr 9:22,311,158...22,321,441
JBrowse link
G H1f4 H1.4 linker histone, cluster member decreases expression ISO Lucanthone results in decreased expression of H1-4 mRNA CTD PMID:21148553 NCBI chr17:41,914,425...41,915,206
Ensembl chr17:41,914,431...41,916,129
JBrowse link
G H1f5 H1.5 linker histone, cluster member decreases expression ISO Lucanthone results in decreased expression of H1-5 mRNA CTD PMID:21148553 NCBI chr17:47,421,875...47,422,905
Ensembl chr17:47,421,843...47,477,387
JBrowse link
G H2ac12 H2A clustered histone 12 decreases expression ISO Lucanthone results in decreased expression of H2AC12 mRNA CTD PMID:21148553 NCBI chr17:47,182,193...47,182,658 JBrowse link
G H2ac21 H2A clustered histone 21 decreases expression ISO Lucanthone results in decreased expression of H2AC21 mRNA CTD PMID:21148553 NCBI chr 2:186,468,224...186,468,657 JBrowse link
G H2ac4 H2A clustered histone 4 decreases expression ISO Lucanthone results in decreased expression of H2AC4 mRNA CTD PMID:21148553 NCBI chr17:47,495,624...47,496,127
Ensembl chr17:47,495,546...47,496,173
JBrowse link
G H2bc8 H2B clustered histone 8 decreases expression ISO Lucanthone results in decreased expression of H2BC8 mRNA CTD PMID:21148553 NCBI chr17:47,404,405...47,405,155 JBrowse link
G H2bc9 H2B clustered histone 9 decreases expression ISO Lucanthone results in decreased expression of H2BC9 mRNA CTD PMID:21148553 NCBI chr17:47,166,372...47,174,369 JBrowse link
G H3c13 H3 clustered histone 13 decreases expression ISO Lucanthone results in decreased expression of H3C13 mRNA CTD PMID:21148553 NCBI chr17:41,959,540...41,960,009
Ensembl chr17:41,958,965...41,960,099
JBrowse link
G H4c14 H4 clustered histone 14 decreases expression ISO Lucanthone results in decreased expression of H4C2 mRNA CTD PMID:21148553 NCBI chr 2:186,520,468...186,520,863
Ensembl chr 4:171,403,627...171,403,938
Ensembl chr17:171,403,627...171,403,938
Ensembl chr17:171,403,627...171,403,938
Ensembl chr17:171,403,627...171,403,938
JBrowse link
G H4f3 H1.3 linker histone, cluster member decreases expression ISO Lucanthone results in decreased expression of H1-3 mRNA CTD PMID:21148553 NCBI chr17:41,979,562...41,980,341
Ensembl chr17:41,796,116...41,980,485
JBrowse link
G Hist1h2bq histone cluster 1 H2B family member Q decreases expression ISO Lucanthone results in decreased expression of H2BC7 mRNA CTD PMID:21148553 NCBI chr17:41,859,955...41,869,889
Ensembl chr17:41,857,231...41,870,107
Ensembl chr17:41,857,231...41,870,107
JBrowse link
G Hjurp Holliday junction recognition protein decreases expression ISO Lucanthone results in decreased expression of HJURP mRNA CTD PMID:21148553 NCBI chr 9:96,301,183...96,315,587
Ensembl chr 9:96,302,530...96,315,657
JBrowse link
G Hmgb2 high mobility group box 2 decreases expression ISO Lucanthone results in decreased expression of HMGB2 mRNA CTD PMID:21148553 NCBI chr16:37,721,374...37,723,950
Ensembl chr16:37,721,379...37,723,860
JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 increases expression ISO Lucanthone results in increased expression of HMGCS1 mRNA CTD PMID:21148553 NCBI chr 2:53,379,457...53,399,807
Ensembl chr 2:53,382,643...53,399,802
JBrowse link
G Hmmr hyaluronan-mediated motility receptor decreases expression ISO Lucanthone results in decreased expression of HMMR mRNA CTD PMID:21148553 NCBI chr10:25,635,249...25,665,389
Ensembl chr10:25,635,915...25,665,390
JBrowse link
G Icam1 intercellular adhesion molecule 1 increases expression ISO Lucanthone results in increased expression of ICAM1 mRNA CTD PMID:21148553 NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:27,829,161...27,841,617
JBrowse link
G Idi1 isopentenyl-diphosphate delta isomerase 1 increases expression ISO Lucanthone results in increased expression of IDI1 mRNA CTD PMID:21148553 NCBI chr17:66,539,761...66,547,524
Ensembl chr17:66,539,763...66,547,524
JBrowse link
G Ifi30 IFI30, lysosomal thiol reductase increases expression ISO Lucanthone results in increased expression of IFI30 mRNA CTD PMID:21148553 NCBI chr16:18,709,570...18,713,635
Ensembl chr16:18,709,563...18,715,711
JBrowse link
G Il18 interleukin 18 decreases expression ISO Lucanthone results in decreased expression of IL18 mRNA CTD PMID:21148553 NCBI chr 8:59,802,072...59,829,275
Ensembl chr 8:59,809,592...59,831,286
JBrowse link
G Il24 interleukin 24 increases expression ISO Lucanthone results in increased expression of IL24 mRNA CTD PMID:21148553 NCBI chr13:44,905,362...44,910,760
Ensembl chr13:44,905,363...44,910,760
JBrowse link
G Il6 interleukin 6 increases expression ISO Lucanthone results in increased expression of IL6 mRNA CTD PMID:21148553 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610
JBrowse link
G Iqgap3 IQ motif containing GTPase activating protein 3 decreases expression ISO Lucanthone results in decreased expression of IQGAP3 mRNA CTD PMID:21148553 NCBI chr 2:175,840,001...175,881,799
Ensembl chr 2:175,839,949...175,881,797
JBrowse link
G Itga3 integrin subunit alpha 3 increases expression ISO Lucanthone results in increased expression of ITGA3 mRNA CTD PMID:21148553 NCBI chr10:80,486,998...80,522,548
Ensembl chr10:80,486,999...80,518,901
JBrowse link
G Kif11 kinesin family member 11 decreases expression ISO Lucanthone results in decreased expression of KIF11 mRNA CTD PMID:21148553 NCBI chr 1:244,494,916...244,589,250
Ensembl chr 1:244,494,875...244,589,250
JBrowse link
G Kif14 kinesin family member 14 decreases expression ISO Lucanthone results in decreased expression of KIF14 mRNA CTD PMID:21148553 NCBI chr13:50,478,646...50,542,256
Ensembl chr13:50,478,721...50,542,248
JBrowse link
G Kif15 kinesin family member 15 decreases expression ISO Lucanthone results in decreased expression of KIF15 mRNA CTD PMID:21148553 NCBI chr 8:131,479,340...131,550,209
Ensembl chr 8:131,479,337...131,550,202
JBrowse link
G Kif20a kinesin family member 20A decreases expression ISO Lucanthone results in decreased expression of KIF20A mRNA CTD PMID:21148553 NCBI chr18:26,504,422...26,512,908
Ensembl chr18:26,504,072...26,512,909
JBrowse link
G Kif20b kinesin family member 20B decreases expression ISO Lucanthone results in decreased expression of KIF20B mRNA CTD PMID:21148553 NCBI chr 1:241,840,898...241,896,451
Ensembl chr 1:241,840,987...241,896,451
JBrowse link
G Kif22 kinesin family member 22 decreases expression ISO Lucanthone results in decreased expression of KIF22 mRNA CTD PMID:21148553 NCBI chr 1:191,065,875...191,080,955
Ensembl chr 1:191,065,875...191,080,878
JBrowse link
G Kif23 kinesin family member 23 decreases expression ISO Lucanthone results in decreased expression of KIF23 mRNA CTD PMID:21148553 NCBI chr 8:71,293,439...71,321,911
Ensembl chr 8:71,293,482...71,320,856
JBrowse link
G Kif2c kinesin family member 2C decreases expression ISO Lucanthone results in decreased expression of KIF2C mRNA CTD PMID:21148553 NCBI chr 5:135,873,925...135,899,267
Ensembl chr 5:135,873,925...135,899,212
JBrowse link
G Kif4a kinesin family member 4A decreases expression ISO Lucanthone results in decreased expression of KIF4A mRNA CTD PMID:21148553 NCBI chr  X:69,761,803...69,864,335
Ensembl chr  X:69,761,883...69,864,335
JBrowse link
G Kifc1 kinesin family member C1 decreases expression ISO Lucanthone results in decreased expression of KIFC1 mRNA CTD PMID:21148553 NCBI chr20:5,000,929...5,018,967
Ensembl chr20:5,000,648...5,018,988
JBrowse link
G Knl1 kinetochore scaffold 1 decreases expression ISO Lucanthone results in decreased expression of KNL1 mRNA CTD PMID:21148553 NCBI chr 3:126,483,498...126,545,774
Ensembl chr 3:126,483,544...126,545,774
JBrowse link
G Lamp3 lysosomal-associated membrane protein 3 decreases expression ISO Lucanthone results in decreased expression of LAMP3 mRNA CTD PMID:21148553 NCBI chr11:94,657,817...94,726,451
Ensembl chr11:94,661,399...94,726,195
JBrowse link
G Lin9 lin-9 DREAM MuvB core complex component decreases expression ISO Lucanthone results in decreased expression of LIN9 mRNA CTD PMID:21148553 NCBI chr13:94,906,185...94,951,541
Ensembl chr13:94,906,548...94,951,539
JBrowse link
G Lrp1 LDL receptor related protein 1 increases expression ISO Lucanthone results in increased expression of LRP1 mRNA CTD PMID:21148553 NCBI chr 7:65,265,639...65,346,196
Ensembl chr 7:65,265,639...65,346,196
JBrowse link
G Lxn latexin increases expression ISO Lucanthone results in increased expression of LXN mRNA CTD PMID:21148553 NCBI chr 2:154,037,604...154,043,473
Ensembl chr 2:154,037,292...154,043,488
JBrowse link
G Mad2l1 mitotic arrest deficient 2 like 1 decreases expression ISO Lucanthone results in decreased expression of MAD2L1 mRNA CTD PMID:21148553 NCBI chr 4:97,236,419...97,247,603
Ensembl chr 4:97,236,503...97,243,222
JBrowse link
G Mboat1 membrane bound O-acyltransferase domain containing 1 decreases expression ISO Lucanthone results in decreased expression of MBOAT1 mRNA CTD PMID:21148553 NCBI chr17:34,540,032...34,653,705
Ensembl chr17:34,540,041...34,653,698
JBrowse link
G Mcm10 minichromosome maintenance 10 replication initiation factor decreases expression ISO Lucanthone results in decreased expression of MCM10 mRNA CTD PMID:21148553 NCBI chr17:78,172,049...78,197,644
Ensembl chr17:78,175,398...78,197,636
JBrowse link
G Mcm8 minichromosome maintenance 8 homologous recombination repair factor decreases expression ISO Lucanthone results in decreased expression of MCM8 mRNA CTD PMID:21148553 NCBI chr 3:140,539,590...140,569,891
Ensembl chr 3:140,539,647...140,569,891
JBrowse link
G Melk maternal embryonic leucine zipper kinase decreases expression ISO Lucanthone results in decreased expression of MELK mRNA CTD PMID:21148553 NCBI chr 5:63,336,151...63,396,254
Ensembl chr 5:63,336,106...63,396,247
JBrowse link
G Mki67 marker of proliferation Ki-67 decreases expression ISO Lucanthone results in decreased expression of MKI67 mRNA CTD PMID:21148553 NCBI chr 1:199,926,150...199,952,847
Ensembl chr 1:199,926,150...199,952,593
JBrowse link
G Mmp1 matrix metallopeptidase 1 increases expression ISO Lucanthone results in increased expression of MMP1 mRNA CTD PMID:21148553 NCBI chr 8:12,943,453...12,963,966
Ensembl chr 8:12,943,453...12,963,964
JBrowse link
G Mnd1 meiotic nuclear divisions 1 decreases expression ISO Lucanthone results in decreased expression of MND1 mRNA CTD PMID:21148553 NCBI chr 2:171,731,523...171,794,124
Ensembl chr 2:171,731,523...171,794,095
JBrowse link
G Mocos molybdenum cofactor sulfurase decreases expression ISO Lucanthone results in decreased expression of MOCOS mRNA CTD PMID:21148553 NCBI chr18:16,206,402...16,251,928
Ensembl chr18:16,206,402...16,251,928
JBrowse link
G Msmo1 methylsterol monooxygenase 1 increases expression ISO Lucanthone results in increased expression of MSMO1 mRNA CTD PMID:21148553 NCBI chr16:29,747,113...29,764,360
Ensembl chr16:29,747,137...29,764,445
JBrowse link
G Mtfr2 mitochondrial fission regulator 2 decreases expression ISO Lucanthone results in decreased expression of MTFR2 mRNA CTD PMID:21148553 NCBI chr 1:16,942,814...16,958,218 JBrowse link
G Mx1 MX dynamin like GTPase 1 increases expression ISO Lucanthone results in increased expression of MX1 mRNA CTD PMID:21148553 NCBI chr11:50,269,056...50,294,699
Ensembl chr11:50,269,057...50,292,904
JBrowse link
G Mybl2 MYB proto-oncogene like 2 decreases expression ISO Lucanthone results in decreased expression of MYBL2 mRNA CTD PMID:21148553 NCBI chr 3:172,124,765...172,153,221
Ensembl chr 3:172,116,550...172,153,221
JBrowse link
G Ncapg non-SMC condensin I complex, subunit G decreases expression ISO Lucanthone results in decreased expression of NCAPG mRNA CTD PMID:21148553 NCBI chr14:69,616,473...69,645,445
Ensembl chr14:69,616,473...69,645,445
JBrowse link
G Ncapg2 non-SMC condensin II complex, subunit G2 decreases expression ISO Lucanthone results in decreased expression of NCAPG2 mRNA CTD PMID:21148553 NCBI chr 6:143,484,651...143,561,850
Ensembl chr 6:143,485,944...143,560,249
JBrowse link
G Ncaph non-SMC condensin I complex, subunit H decreases expression ISO Lucanthone results in decreased expression of NCAPH mRNA CTD PMID:21148553 NCBI chr 3:134,825,271...134,852,502
Ensembl chr 3:134,825,271...134,852,502
JBrowse link
G Ndc80 NDC80 kinetochore complex component decreases expression ISO Lucanthone results in decreased expression of NDC80 mRNA CTD PMID:21148553 NCBI chr 9:118,853,806...118,887,582
Ensembl chr 9:118,853,806...118,887,568
JBrowse link
G Nek2 NIMA-related kinase 2 decreases expression ISO Lucanthone results in decreased expression of NEK2 mRNA CTD PMID:21148553 NCBI chr13:105,936,809...105,950,054
Ensembl chr13:105,936,788...105,950,056
JBrowse link
G Nemp1 nuclear envelope integral membrane protein 1 decreases expression ISO Lucanthone results in decreased expression of NEMP1 mRNA CTD PMID:21148553 NCBI chr 7:65,399,297...65,424,054
Ensembl chr 7:65,399,381...65,424,055
JBrowse link
G Niban1 niban apoptosis regulator 1 decreases expression ISO Lucanthone results in decreased expression of NIBAN1 mRNA CTD PMID:21148553 NCBI chr13:66,224,219...66,377,728
Ensembl chr13:66,224,021...66,377,724
JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 increases expression ISO Lucanthone results in increased expression of NR4A2 mRNA CTD PMID:21148553 NCBI chr 3:62,098,739...62,115,926
Ensembl chr 3:62,098,743...62,106,769
JBrowse link
G Nuf2 NUF2 component of NDC80 kinetochore complex decreases expression ISO Lucanthone results in decreased expression of NUF2 mRNA CTD PMID:21148553 NCBI chr13:84,226,448...84,290,957
Ensembl chr13:84,226,509...84,255,598
JBrowse link
G Nusap1 nucleolar and spindle associated protein 1 decreases expression ISO Lucanthone results in decreased expression of NUSAP1 mRNA CTD PMID:21148553 NCBI chr 3:127,057,220...127,092,779
Ensembl chr 3:127,057,265...127,087,237
JBrowse link
G Orc6 origin recognition complex, subunit 6 decreases expression ISO Lucanthone results in decreased expression of ORC6 mRNA CTD PMID:21148553 NCBI chr19:37,931,085...37,938,856
Ensembl chr19:37,931,090...37,938,856
JBrowse link
G Otub2 OTU deubiquitinase, ubiquitin aldehyde binding 2 increases expression ISO Lucanthone results in increased expression of OTUB2 mRNA CTD PMID:21148553 NCBI chr 6:128,309,863...128,328,444
Ensembl chr 6:128,299,693...128,328,433
JBrowse link
G Pbk PDZ binding kinase decreases expression ISO Lucanthone results in decreased expression of PBK mRNA CTD PMID:21148553 NCBI chr15:44,198,506...44,209,572
Ensembl chr15:44,198,544...44,209,570
JBrowse link
G Pclaf PCNA clamp associated factor decreases expression ISO Lucanthone results in decreased expression of PCLAF mRNA CTD PMID:21148553 NCBI chr 8:75,311,028...75,328,108
Ensembl chr 8:75,315,707...75,328,106
JBrowse link
G Phgdh phosphoglycerate dehydrogenase decreases expression ISO Lucanthone results in decreased expression of PHGDH mRNA CTD PMID:21148553 NCBI chr 2:188,595,700...188,624,789
Ensembl chr 2:188,595,700...188,624,789
JBrowse link
G Plk1 polo-like kinase 1 decreases expression ISO Lucanthone results in decreased expression of PLK1 mRNA CTD PMID:21148553 NCBI chr 1:186,147,658...186,157,637
Ensembl chr 1:186,147,658...186,157,637
JBrowse link
G Plk4 polo-like kinase 4 decreases expression ISO Lucanthone results in decreased expression of PLK4 mRNA CTD PMID:21148553 NCBI chr 2:125,730,480...125,748,894
Ensembl chr 2:125,730,460...125,748,892
JBrowse link
G Pole2 DNA polymerase epsilon 2, accessory subunit decreases expression ISO Lucanthone results in decreased expression of POLE2 mRNA CTD PMID:21148553 NCBI chr 6:93,410,713...93,448,782
Ensembl chr 6:93,410,758...93,435,361
JBrowse link
G Prc1 protein regulator of cytokinesis 1 decreases expression ISO Lucanthone results in decreased expression of PRC1 mRNA CTD PMID:21148553 NCBI chr 1:143,659,312...143,681,019
Ensembl chr 1:143,659,481...143,681,012
JBrowse link
G Prim1 DNA primase subunit 1 decreases expression ISO Lucanthone results in decreased expression of PRIM1 mRNA CTD PMID:21148553 NCBI chr 7:1,031,436...1,047,134 JBrowse link
G Prr11 proline rich 11 decreases expression ISO Lucanthone results in decreased expression of PRR11 mRNA CTD PMID:21148553 NCBI chr10:72,396,127...72,440,643
Ensembl chr10:72,398,667...72,418,275
JBrowse link
G Psat1 phosphoserine aminotransferase 1 decreases expression ISO Lucanthone results in decreased expression of PSAT1 mRNA CTD PMID:21148553 NCBI chr 1:222,623,553...222,646,187
Ensembl chr 1:222,623,556...222,655,693
JBrowse link
G Psmc3ip PSMC3 interacting protein decreases expression ISO Lucanthone results in decreased expression of PSMC3IP mRNA CTD PMID:21148553 NCBI chr10:86,524,546...86,527,764
Ensembl chr10:86,524,571...86,527,666
JBrowse link
G Ptchd4 patched domain containing 4 increases expression ISO Lucanthone results in increased expression of PTCHD4 mRNA CTD PMID:21148553 NCBI chr 9:25,951,395...26,163,296
Ensembl chr 9:25,959,954...26,163,284
JBrowse link
G Pxdn peroxidasin increases expression ISO Lucanthone results in increased expression of PXDN mRNA CTD PMID:21148553 NCBI chr 6:52,308,347...52,385,943
Ensembl chr 6:52,308,364...52,385,942
JBrowse link
G Racgap1 Rac GTPase-activating protein 1 decreases expression ISO Lucanthone results in decreased expression of RACGAP1 mRNA CTD PMID:21148553 NCBI chr 7:132,629,789...132,659,738
Ensembl chr 7:132,620,595...132,659,738
JBrowse link
G Rad51 RAD51 recombinase decreases expression ISO Lucanthone results in decreased expression of RAD51 mRNA CTD PMID:21148553 NCBI chr 3:126,554,210...126,578,888
Ensembl chr 3:126,554,190...126,579,469
JBrowse link
G Rad51ap1 RAD51 associated protein 1 decreases expression ISO Lucanthone results in decreased expression of RAD51AP1 mRNA CTD PMID:21148553 NCBI chr 4:161,445,610...161,458,661
Ensembl chr 4:161,445,512...161,458,680
JBrowse link
G Rrm2 ribonucleotide reductase regulatory subunit M2 decreases expression ISO Lucanthone results in decreased expression of RRM2 mRNA CTD PMID:21148553 NCBI chr 6:47,044,755...47,075,370
Ensembl chr 6:47,067,690...47,075,370
JBrowse link
G Sat1 spermidine/spermine N1-acetyl transferase 1 increases expression ISO Lucanthone results in increased expression of SAT1 mRNA CTD PMID:21148553 NCBI chr  X:44,008,089...44,011,376
Ensembl chr  X:44,006,781...44,011,374
JBrowse link
G Scube1 signal peptide, CUB domain and EGF like domain containing 1 increases expression ISO Lucanthone results in increased expression of SCUBE1 mRNA CTD PMID:21148553 NCBI chr 7:116,639,027...116,760,986
Ensembl chr 7:116,642,231...116,760,944
JBrowse link
G Sectm1b secreted and transmembrane 1B increases expression ISO Lucanthone results in increased expression of SECTM1 mRNA CTD PMID:21148553 NCBI chr10:106,822,397...106,832,105
Ensembl chr10:106,822,397...106,832,104
JBrowse link
G Serpinb2 serpin family B member 2 increases expression ISO Lucanthone results in increased expression of SERPINB2 mRNA CTD PMID:21148553 NCBI chr13:24,051,933...24,065,032
Ensembl chr13:24,056,021...24,065,031
JBrowse link
G Sgo1 shugoshin 1 decreases expression ISO Lucanthone results in decreased expression of SGO1 mRNA CTD PMID:21148553 NCBI chr 9:6,908,661...6,943,483
Ensembl chr 9:6,908,661...6,924,415
JBrowse link
G Sgo2 shugoshin 2 decreases expression ISO Lucanthone results in decreased expression of SGO2 mRNA CTD PMID:21148553 NCBI chr 9:67,032,083...67,067,439
Ensembl chr 9:67,042,833...67,068,152
JBrowse link
G Shc4 SHC adaptor protein 4 increases expression ISO Lucanthone results in increased expression of SHC4 mRNA CTD PMID:21148553 NCBI chr 3:133,334,026...133,428,404
Ensembl chr 3:133,334,034...133,427,826
JBrowse link
G Shcbp1 SHC binding and spindle associated 1 decreases expression ISO Lucanthone results in decreased expression of SHCBP1 mRNA CTD PMID:21148553 NCBI chr16:91,373,843...91,405,409
Ensembl chr16:91,373,871...91,405,409
JBrowse link
G Slc1a4 solute carrier family 1 member 4 decreases expression ISO Lucanthone results in decreased expression of SLC1A4 mRNA CTD PMID:21148553 NCBI chr14:98,718,646...98,761,672
Ensembl chr14:98,730,450...98,761,790
JBrowse link
G Smc4 structural maintenance of chromosomes 4 decreases expression ISO Lucanthone results in decreased expression of SMC4 mRNA CTD PMID:21148553 NCBI chr 2:155,550,262...155,578,695
Ensembl chr 2:155,550,262...155,581,937
JBrowse link
G Spag5 sperm associated antigen 5 decreases expression ISO Lucanthone results in decreased expression of SPAG5 mRNA CTD PMID:21148553 NCBI chr10:63,693,300...63,714,813
Ensembl chr10:63,696,466...63,714,811
JBrowse link
G Spata18 spermatogenesis associated 18 increases expression ISO Lucanthone results in increased expression of SPATA18 mRNA CTD PMID:21148553 NCBI chr14:34,885,995...34,912,704
Ensembl chr14:34,885,995...34,912,736
JBrowse link
G Spc25 SPC25 component of NDC80 kinetochore complex decreases expression ISO Lucanthone results in decreased expression of SPC25 mRNA CTD PMID:21148553 NCBI chr 3:74,337,872...74,396,825
Ensembl chr 3:74,383,548...74,396,718
JBrowse link
G Spdl1 spindle apparatus coiled-coil protein 1 decreases expression ISO Lucanthone results in decreased expression of SPDL1 mRNA CTD PMID:21148553 NCBI chr10:19,773,456...19,798,341
Ensembl chr10:19,773,457...19,798,297
JBrowse link
G Stmn1 stathmin 1 decreases expression ISO Lucanthone results in decreased expression of STMN1 mRNA CTD PMID:21148553 NCBI chr 5:151,964,308...151,970,843
Ensembl chr 5:151,964,351...151,970,842
JBrowse link
G Sulf2 sulfatase 2 increases expression ISO Lucanthone results in increased expression of SULF2 mRNA CTD PMID:21148553 NCBI chr 3:175,241,322...175,323,808
Ensembl chr 3:175,241,322...175,323,651
JBrowse link
G Tcp11l2 t-complex 11 like 2 increases expression ISO Lucanthone results in increased expression of TCP11L2 mRNA CTD PMID:21148553 NCBI chr 7:21,037,955...21,072,857
Ensembl chr 7:21,037,958...21,064,681
JBrowse link
G Tfpi2 tissue factor pathway inhibitor 2 increases expression ISO Lucanthone results in increased expression of TFPI2 mRNA CTD PMID:21148553 NCBI chr 4:32,936,462...32,941,385
Ensembl chr 4:32,936,854...32,941,426
JBrowse link
G Tiparp TCDD-inducible poly(ADP-ribose) polymerase increases expression ISO Lucanthone results in increased expression of TIPARP mRNA CTD PMID:21148553 NCBI chr 2:152,063,769...152,090,414
Ensembl chr 2:152,063,751...152,090,406
JBrowse link
G Tmem45a transmembrane protein 45A increases expression ISO Lucanthone results in increased expression of TMEM45A mRNA CTD PMID:21148553 NCBI chr11:57,181,686...57,268,630
Ensembl chr11:57,182,785...57,282,722
JBrowse link
G Tnfsf15 TNF superfamily member 15 increases expression ISO Lucanthone results in increased expression of TNFSF15 mRNA CTD PMID:21148553 NCBI chr 5:82,150,376...82,171,743
Ensembl chr 5:82,150,376...82,171,882
JBrowse link
G Top2a DNA topoisomerase II alpha decreases expression ISO Lucanthone results in decreased expression of TOP2A mRNA CTD PMID:21148553 NCBI chr10:84,441,954...84,473,093
Ensembl chr10:84,441,954...84,473,366
JBrowse link
G Tp53i3 tumor protein p53 inducible protein 3 increases expression ISO Lucanthone results in increased expression of TP53I3 mRNA CTD PMID:21148553 NCBI chr 6:33,537,779...33,545,204 JBrowse link
G Tp53inp1 tumor protein p53 inducible nuclear protein 1 increases expression ISO Lucanthone results in increased expression of TP53INP1 mRNA CTD PMID:21148553 NCBI chr 5:29,051,267...29,069,486
Ensembl chr 5:29,051,264...29,069,484
JBrowse link
G Tpx2 TPX2, microtubule nucleation factor decreases expression ISO Lucanthone results in decreased expression of TPX2 mRNA CTD PMID:21148553 NCBI chr 3:161,778,709...161,820,941
Ensembl chr 3:161,778,742...161,820,724
JBrowse link
G Ttk Ttk protein kinase decreases expression ISO Lucanthone results in decreased expression of TTK mRNA CTD PMID:21148553 NCBI chr 8:93,632,678...93,672,664
Ensembl chr 8:93,634,319...93,672,664
JBrowse link
G Ube2t ubiquitin-conjugating enzyme E2T decreases expression ISO Lucanthone results in decreased expression of UBE2T mRNA CTD PMID:21148553 NCBI chr13:48,955,166...48,965,668
Ensembl chr13:48,955,183...48,966,646
JBrowse link
G Wdr76 WD repeat domain 76 decreases expression ISO Lucanthone results in decreased expression of WDR76 mRNA CTD PMID:21148553 NCBI chr 3:128,910,500...128,945,241
Ensembl chr 3:128,910,503...128,945,239
JBrowse link
G Xrcc2 X-ray repair cross complementing 2 decreases expression ISO Lucanthone results in decreased expression of XRCC2 mRNA CTD PMID:21148553 NCBI chr 4:10,157,130...10,237,089
Ensembl chr 4:10,157,800...10,176,407
JBrowse link
G Zwint ZW10 interacting kinetochore protein decreases expression ISO Lucanthone results in decreased expression of ZWINT mRNA CTD PMID:21148553 NCBI chr20:15,502,559...15,953,701
Ensembl chr20:15,937,396...15,953,203
JBrowse link
hycanthone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity ISO Hycanthone results in increased activity of NR1I2 protein CTD PMID:25455453 NCBI chr11:75,965,717...76,006,733
Ensembl chr11:75,965,632...76,002,380
JBrowse link
G Tp53 tumor protein p53 affects activity ISO Hycanthone affects the activity of TP53 protein CTD PMID:35435491 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20862
    role 20820
      application 20621
        pro-agent 12349
          prodrug 12109
            lucanthone 189
              hycanthone 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 20862
    subatomic particle 20860
      composite particle 20860
        hadron 20860
          baryon 20860
            nucleon 20860
              atomic nucleus 20860
                atom 20860
                  main group element atom 20781
                    p-block element atom 20781
                      carbon group element atom 20715
                        carbon atom 20710
                          organic molecular entity 20710
                            organic molecule 20654
                              organic cyclic compound 20404
                                organic heterocyclic compound 19388
                                  organic heteropolycyclic compound 18651
                                    organic heterotricyclic compound 16078
                                      thioxanthenes 196
                                        lucanthone 189
                                          hycanthone 2
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