CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: lucanthone
Accession: CHEBI:51052
browse the term
Definition: A thioxanthen-9-one compound having a methyl substituent at the 1-position and a 2-[(diethylamino)ethyl]amino substituent at the 4-position. Formerly used for the treatment of schistosomiasis. It is a prodrug, being metabolised to hycanthone.
Synonyms: exact_synonym: 1-{[2-(diethylamino)ethyl]amino}-4-methyl-9H-thioxanthen-9-one
related_synonym: 1-diethylaminoethylethylamino-4-methyl-thioxanthenone; 1-{[2-(diethylamino)ethyl]amino}-4-methylthioxanthen-9-one; Formula=C20H24N2OS; InChI=1S/C20H24N2OS/c1-4-22(5-2)13-12-21-16-11-10-14(3)20-18(16)19(23)15-8-6-7-9-17(15)24-20/h6-11,21H,4-5,12-13H2,1-3H3; InChIKey=FBQPGGIHOFZRGH-UHFFFAOYSA-N; SMILES=CCN(CC)CCNc1ccc(C)c2sc3ccccc3c(=O)c12; lucanthonum; lucantona
alt_id: CHEBI:19039; CHEBI:6552
xref: CAS:479-50-5; DrugBank:DB04967; Drug_Central:1616; HMDB:HMDB0015607; KEGG:C11715
xref_mesh: MESH:D008154
xref: PMID:21148553; PMID:21935361; PMID:4368942; PMID:6887199; PMID:9169823; Reaxys:312369; Wikipedia:Lucanthone
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Abca12
ATP binding cassette subfamily A member 12
increases expression
ISO
Lucanthone results in increased expression of ABCA12 mRNA
CTD
PMID:21148553
NCBI chr 9:80,272,121...80,445,340
Ensembl chr 9:80,272,127...80,445,340
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Acta2
actin alpha 2, smooth muscle
increases expression
ISO
Lucanthone results in increased expression of ACTA2 mRNA
CTD
PMID:21148553
NCBI chr 1:241,159,723...241,172,503
Ensembl chr 1:241,159,724...241,172,503
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Aldh1l2
aldehyde dehydrogenase 1 family, member L2
decreases expression
ISO
Lucanthone results in decreased expression of ALDH1L2 mRNA
CTD
PMID:21148553
NCBI chr 7:22,141,872...22,193,403
Ensembl chr 7:22,141,842...22,193,398
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Anln
anillin, actin binding protein
decreases expression
ISO
Lucanthone results in decreased expression of ANLN mRNA
CTD
PMID:21148553
NCBI chr 8:29,134,222...29,197,513
Ensembl chr 8:29,134,222...29,197,513
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Anxa3
annexin A3
decreases expression
ISO
Lucanthone results in decreased expression of ANXA3 mRNA
CTD
PMID:21148553
NCBI chr14:13,031,675...13,085,678
Ensembl chr14:13,023,762...13,085,849
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Aqp3
aquaporin 3 (Gill blood group)
increases expression
ISO
Lucanthone results in increased expression of AQP3 mRNA
CTD
PMID:21148553
NCBI chr 5:61,035,165...61,040,683
Ensembl chr 5:61,035,166...61,040,685
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Arhgap11a
Rho GTPase activating protein 11A
decreases expression
ISO
Lucanthone results in decreased expression of ARHGAP11A mRNA
CTD
PMID:21148553
NCBI chr 3:121,045,187...121,071,985
Ensembl chr 3:121,045,187...121,061,468
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Asns
asparagine synthetase (glutamine-hydrolyzing)
decreases expression
ISO
Lucanthone results in decreased expression of ASNS mRNA
CTD
PMID:21148553
NCBI chr 4:36,752,061...36,769,970
Ensembl chr 4:36,751,802...36,776,050
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Aspm
assembly factor for spindle microtubules
decreases expression
ISO
Lucanthone results in decreased expression of ASPM mRNA
CTD
PMID:21148553
NCBI chr13:53,625,584...53,674,489
Ensembl chr13:53,625,584...53,674,489
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Atad2
ATPase family, AAA domain containing 2
decreases expression
ISO
Lucanthone results in decreased expression of ATAD2 mRNA
CTD
PMID:21148553
NCBI chr 7:91,523,626...91,566,238
Ensembl chr 7:91,523,626...91,566,238
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Aurka
aurora kinase A
decreases expression
ISO
Lucanthone results in decreased expression of AURKA mRNA
CTD
PMID:21148553
NCBI chr 3:181,546,742...181,562,890
Ensembl chr 3:181,546,742...181,562,771
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Aurkb
aurora kinase B
decreases expression
ISO
Lucanthone results in decreased expression of AURKB mRNA
CTD
PMID:21148553
NCBI chr10:54,243,116...54,249,675
Ensembl chr10:54,242,850...54,252,285
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Birc5
baculoviral IAP repeat-containing 5
decreases expression
ISO
Lucanthone results in decreased expression of BIRC5 mRNA
CTD
PMID:21148553
NCBI chr10:103,567,369...103,580,069
Ensembl chr10:103,572,080...103,582,155
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Blm
BLM RecQ like helicase
decreases expression
ISO
Lucanthone results in decreased expression of BLM mRNA
CTD
PMID:21148553
NCBI chr 1:143,819,072...143,905,300
Ensembl chr 1:143,819,090...143,905,210
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Brca1
BRCA1, DNA repair associated
decreases expression
ISO
Lucanthone results in decreased expression of BRCA1 mRNA
CTD
PMID:21148553
NCBI chr10:86,917,693...86,978,012
Ensembl chr10:86,917,693...86,977,763
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Brca2
BRCA2, DNA repair associated
decreases expression
ISO
Lucanthone results in decreased expression of BRCA2 mRNA
CTD
PMID:21148553
NCBI chr12:4,895,092...4,939,340
Ensembl chr12:4,895,447...4,936,194
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Bub1
BUB1 mitotic checkpoint serine/threonine kinase
decreases expression
ISO
Lucanthone results in decreased expression of BUB1 mRNA
CTD
PMID:21148553
NCBI chr 3:135,473,525...135,504,921
Ensembl chr 3:135,472,582...135,504,921
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Bub1b
BUB1 mitotic checkpoint serine/threonine kinase B
decreases expression
ISO
Lucanthone results in decreased expression of BUB1B mRNA
CTD
PMID:21148553
NCBI chr 3:126,017,019...126,069,470
Ensembl chr 3:126,017,045...126,069,796
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C2h5orf34
similar to human chromosome 5 open reading frame 34
decreases expression
ISO
Lucanthone results in decreased expression of C5ORF34 mRNA
CTD
PMID:21148553
NCBI chr 2:53,287,353...53,309,804
Ensembl chr 2:53,287,957...53,309,806
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Ccn3
cellular communication network factor 3
increases expression
ISO
Lucanthone results in increased expression of CCN3 mRNA
CTD
PMID:21148553
NCBI chr 7:87,983,788...87,990,810
Ensembl chr 7:87,982,216...87,994,581
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Ccna2
cyclin A2
decreases expression
ISO
Lucanthone results in decreased expression of CCNA2 mRNA
CTD
PMID:21148553
NCBI chr 2:121,355,363...121,361,762
Ensembl chr 2:121,355,363...121,361,701
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Ccnb1
cyclin B1
decreases expression
ISO
Lucanthone results in decreased expression of CCNB1 mRNA
CTD
PMID:21148553
NCBI chr 2:33,646,252...33,655,225
Ensembl chr 2:33,646,252...33,655,225
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Ccnb2
cyclin B2
decreases expression
ISO
Lucanthone results in decreased expression of CCNB2 mRNA
CTD
PMID:21148553
NCBI chr 8:79,968,459...79,981,717
Ensembl chr 8:79,968,465...79,981,682
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Cdc20
cell division cycle 20
decreases expression
ISO
Lucanthone results in decreased expression of CDC20 mRNA
CTD
PMID:21148553
NCBI chr 5:137,251,596...137,255,799
Ensembl chr 5:137,251,596...137,255,799
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Cdc25c
cell division cycle 25C
decreases expression
ISO
Lucanthone results in decreased expression of CDC25C mRNA
CTD
PMID:21148553
NCBI chr18:26,608,483...26,630,292
Ensembl chr18:26,609,959...26,630,292
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Cdc45
cell division cycle 45
decreases expression
ISO
Lucanthone results in decreased expression of CDC45 mRNA
CTD
PMID:21148553
NCBI chr11:95,689,702...95,714,980
Ensembl chr11:95,689,919...95,714,981
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Cdc6
cell division cycle 6
decreases expression
ISO
Lucanthone results in decreased expression of CDC6 mRNA
CTD
PMID:21148553
NCBI chr10:84,360,361...84,374,239
Ensembl chr10:84,360,381...84,374,241
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Cdca2
cell division cycle associated 2
decreases expression
ISO
Lucanthone results in decreased expression of CDCA2 mRNA
CTD
PMID:21148553
NCBI chr15:46,071,360...46,117,524
Ensembl chr15:46,071,360...46,116,639
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Cdk1
cyclin-dependent kinase 1
decreases expression
ISO
Lucanthone results in decreased expression of CDK1 mRNA
CTD
PMID:21148553
NCBI chr20:19,265,252...19,280,456
Ensembl chr20:19,265,289...19,280,455
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Cdkn1a
cyclin-dependent kinase inhibitor 1A
increases expression
ISO
Lucanthone results in increased expression of CDKN1A mRNA
CTD
PMID:21148553
NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969
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Cdkn3
cyclin-dependent kinase inhibitor 3
decreases expression
ISO
Lucanthone results in decreased expression of CDKN3 mRNA
CTD
PMID:21148553
NCBI chr15:22,502,299...22,513,725
Ensembl chr15:22,502,382...22,513,722
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Cenpa
centromere protein A
decreases expression
ISO
Lucanthone results in decreased expression of CENPA mRNA
CTD
PMID:21148553
NCBI chr 6:31,420,062...31,431,703
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Cenpe
centromere protein E
decreases expression
ISO
Lucanthone results in decreased expression of CENPE mRNA
CTD
PMID:21148553
NCBI chr 2:226,310,970...226,369,636
Ensembl chr 2:226,300,798...226,369,636
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Cenpf
centromere protein F
decreases expression
ISO
Lucanthone results in decreased expression of CENPF mRNA
CTD
PMID:21148553
NCBI chr13:103,715,344...103,760,931
Ensembl chr13:103,715,344...103,760,886
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Cenpi
centromere protein I
decreases expression
ISO
Lucanthone results in decreased expression of CENPI mRNA
CTD
PMID:21148553
NCBI chr X:101,809,192...101,860,935
Ensembl chr X:101,809,659...101,860,934
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Cenpk
centromere protein K
decreases expression
ISO
Lucanthone results in decreased expression of CENPK mRNA
CTD
PMID:21148553
NCBI chr 2:37,094,163...37,155,158
Ensembl chr 2:37,094,248...37,119,488
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Cenpl
centromere protein L
decreases expression
ISO
Lucanthone results in decreased expression of CENPL mRNA
CTD
PMID:21148553
NCBI chr13:75,870,479...75,885,466
Ensembl chr13:75,870,489...75,905,250
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Cenpu
centromere protein U
decreases expression
ISO
Lucanthone results in decreased expression of CENPU mRNA
CTD
PMID:21148553
NCBI chr16:52,448,446...52,471,662
Ensembl chr16:52,425,096...52,471,662
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Cep55
centrosomal protein 55
decreases expression
ISO
Lucanthone results in decreased expression of CEP55 mRNA
CTD
PMID:21148553
NCBI chr 1:245,245,272...245,260,835
Ensembl chr 1:245,245,306...245,260,890
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Cip2a
cellular inhibitor of PP2A
decreases expression
ISO
Lucanthone results in decreased expression of CIP2A mRNA
CTD
PMID:21148553
NCBI chr11:65,255,123...65,285,914
Ensembl chr11:65,255,123...65,285,914
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Cit
citron rho-interacting serine/threonine kinase
decreases expression
ISO
Lucanthone results in decreased expression of CIT mRNA
CTD
PMID:21148553
NCBI chr12:46,263,881...46,425,642
Ensembl chr12:46,266,369...46,424,656
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Ckap2l
cytoskeleton associated protein 2-like
decreases expression
ISO
Lucanthone results in decreased expression of CKAP2L mRNA
CTD
PMID:21148553
NCBI chr 3:136,950,390...136,977,503
Ensembl chr 3:136,950,381...136,977,565
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Cks1b
CDC28 protein kinase regulatory subunit 1B
decreases expression
ISO
Lucanthone results in decreased expression of CKS1B mRNA
CTD
PMID:21148553
NCBI chr 2:177,130,751...177,135,333
Ensembl chr 2:177,130,777...177,135,365
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Clca2
chloride channel accessory 2
increases expression
ISO
Lucanthone results in increased expression of CLCA2 mRNA
CTD
PMID:21148553
NCBI chr 2:236,655,419...236,682,669
Ensembl chr 2:236,639,545...236,685,129
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Cldn1
claudin 1
decreases expression
ISO
Lucanthone results in decreased expression of CLDN1 mRNA
CTD
PMID:21148553
NCBI chr11:87,926,376...87,941,533
Ensembl chr11:87,926,337...87,941,529
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Clgn
calmegin
decreases expression
ISO
Lucanthone results in decreased expression of CLGN mRNA
CTD
PMID:21148553
NCBI chr19:41,601,568...41,633,207
Ensembl chr19:41,601,568...41,633,325
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Cmklr2
chemerin chemokine-like receptor 2
decreases expression
ISO
Lucanthone results in decreased expression of CMKLR2 mRNA
CTD
PMID:21148553
NCBI chr 9:72,077,164...72,111,979
Ensembl chr 9:72,078,608...72,116,257
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Ctsd
cathepsin D
increases expression
ISO
Lucanthone results in increased expression of CTSD mRNA; Lucanthone results in increased expression of CTSD protein
CTD
PMID:21148553
NCBI chr 1:206,956,945...206,968,821
Ensembl chr 1:206,956,944...206,968,821
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Cxcl10
C-X-C motif chemokine ligand 10
increases expression
ISO
Lucanthone results in increased expression of CXCL10 mRNA
CTD
PMID:21148553
NCBI chr14:15,989,066...15,991,263
Ensembl chr14:15,989,018...15,991,261
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Cyp1a1
cytochrome P450, family 1, subfamily a, polypeptide 1
increases expression
ISO
Lucanthone results in increased expression of CYP1A1 mRNA
CTD
PMID:21148553
NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012
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Ddit3
DNA-damage inducible transcript 3
decreases expression
ISO
Lucanthone results in decreased expression of DDIT3 mRNA
CTD
PMID:21148553
NCBI chr 7:65,001,695...65,006,517
Ensembl chr 7:65,005,501...65,006,509
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Depdc1
DEP domain containing 1
decreases expression
ISO
Lucanthone results in decreased expression of DEPDC1 mRNA
CTD
PMID:21148553
NCBI chr 2:251,343,250...251,376,709
Ensembl chr 2:251,343,281...251,376,709
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Depdc1b
DEP domain containing 1B
decreases expression
ISO
Lucanthone results in decreased expression of DEPDC1B mRNA
CTD
PMID:21148553
NCBI chr 2:41,605,686...41,697,207
Ensembl chr 2:41,624,922...41,697,202
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Dhcr24
24-dehydrocholesterol reductase
increases expression
ISO
Lucanthone results in increased expression of DHCR24 mRNA
CTD
PMID:21148553
NCBI chr 5:126,573,366...126,599,940
Ensembl chr 5:126,573,338...126,599,936
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Diaph3
diaphanous-related formin 3
decreases expression
ISO
Lucanthone results in decreased expression of DIAPH3 mRNA
CTD
PMID:21148553
NCBI chr15:68,951,992...69,421,623
Ensembl chr15:68,951,989...69,421,552
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Dlgap5
DLG associated protein 5
decreases expression
ISO
Lucanthone results in decreased expression of DLGAP5 mRNA
CTD
PMID:21148553
NCBI chr15:23,113,678...23,144,281
Ensembl chr15:23,113,678...23,144,176
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Dnai3
dynein axonemal intermediate chain 3
increases expression
ISO
Lucanthone results in increased expression of DNAI3 mRNA
CTD
PMID:21148553
NCBI chr 2:237,608,202...237,666,465
Ensembl chr 2:237,604,068...237,666,465
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Dpp4
dipeptidylpeptidase 4
increases expression
ISO
Lucanthone results in increased expression of DPP4 mRNA
CTD
PMID:21148553
NCBI chr 3:67,370,794...67,452,422
Ensembl chr 3:67,370,804...67,452,422
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Dtl
denticleless E3 ubiquitin protein ligase homolog
decreases expression
ISO
Lucanthone results in decreased expression of DTL mRNA
CTD
PMID:21148553
NCBI chr13:105,646,908...105,685,921
Ensembl chr13:105,646,908...105,686,174
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Ect2
epithelial cell transforming 2
decreases expression
ISO
Lucanthone results in decreased expression of ECT2 mRNA
CTD
PMID:21148553
NCBI chr 2:111,904,522...111,966,786
Ensembl chr 2:111,904,522...111,966,626
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Efemp1
EGF containing fibulin extracellular matrix protein 1
decreases expression
ISO
Lucanthone results in decreased expression of EFEMP1 mRNA
CTD
PMID:21148553
NCBI chr14:106,811,769...106,890,961
Ensembl chr14:106,802,304...106,892,808
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Ercc6l
ERCC excision repair 6 like, spindle assembly checkpoint helicase
decreases expression
ISO
Lucanthone results in decreased expression of ERCC6L mRNA
CTD
PMID:21148553
NCBI chr X:71,285,380...71,301,186
Ensembl chr X:71,285,380...71,301,186
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Esco2
establishment of sister chromatid cohesion N-acetyltransferase 2
decreases expression
ISO
Lucanthone results in decreased expression of ESCO2 mRNA
CTD
PMID:21148553
NCBI chr15:44,210,124...44,230,785
Ensembl chr15:44,210,641...44,231,304 Ensembl chr15:44,210,641...44,231,304
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Espl1
extra spindle pole bodies like 1, separase
decreases expression
ISO
Lucanthone results in decreased expression of ESPL1 mRNA
CTD
PMID:21148553
NCBI chr 7:135,302,460...135,329,570
Ensembl chr 7:135,302,716...135,329,570
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Exo1
exonuclease 1
decreases expression
ISO
Lucanthone results in decreased expression of EXO1 mRNA
CTD
PMID:21148553
NCBI chr13:90,341,947...90,366,861
Ensembl chr13:90,342,018...90,366,861
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Exosc8
exosome component 8
decreases expression
ISO
Lucanthone results in decreased expression of EXOSC8 mRNA
CTD
PMID:21148553
NCBI chr 2:141,080,568...141,087,112
Ensembl chr 2:141,080,568...141,087,229
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Ezh2
enhancer of zeste 2 polycomb repressive complex 2 subunit
decreases expression
ISO
Lucanthone results in decreased expression of EZH2 mRNA
CTD
PMID:21148553
NCBI chr 4:77,624,223...77,698,598
Ensembl chr 4:77,624,223...77,687,183
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Fam72a
family with sequence similarity 72, member A
decreases expression
ISO
Lucanthone results in decreased expression of FAM72A mRNA
CTD
PMID:21148553
NCBI chr13:45,519,940...45,531,322
Ensembl chr13:45,519,818...45,531,324
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Fanci
FA complementation group I
decreases expression
ISO
Lucanthone results in decreased expression of FANCI mRNA
CTD
PMID:21148553
NCBI chr 1:142,736,636...142,792,999
Ensembl chr 1:142,736,653...142,792,999
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Fbxo5
F-box protein 5
decreases expression
ISO
Lucanthone results in decreased expression of FBXO5 mRNA
CTD
PMID:21148553
NCBI chr 1:44,601,412...44,607,781
Ensembl chr 1:44,601,412...44,607,781
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Flg
filaggrin
decreases expression
ISO
Lucanthone results in decreased expression of FLG mRNA
CTD
PMID:21148553
NCBI chr 2:181,583,801...181,596,464
Ensembl chr 2:181,583,808...181,595,968
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Foxm1
forkhead box M1
decreases expression
ISO
Lucanthone results in decreased expression of FOXM1 mRNA
CTD
PMID:21148553
NCBI chr 4:163,325,628...163,338,100
Ensembl chr 4:163,325,614...163,337,172
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Gbp1
guanylate binding protein 1
decreases expression
ISO
Lucanthone results in decreased expression of GBP1 mRNA
CTD
PMID:21148553
NCBI chr 2:234,071,366...234,106,012
Ensembl chr 2:234,190,708...234,206,802 Ensembl chr 2:234,190,708...234,206,802
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Gdf15
growth differentiation factor 15
increases expression
ISO
Lucanthone results in increased expression of GDF15 mRNA
CTD
PMID:21148553
NCBI chr16:18,838,436...18,842,022
Ensembl chr16:18,838,436...18,842,022
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Gpnmb
glycoprotein nmb
increases expression
ISO
Lucanthone results in increased expression of GPNMB mRNA
CTD
PMID:21148553
NCBI chr 4:79,341,128...79,362,366
Ensembl chr 4:79,341,021...79,380,240
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Gpx8
glutathione peroxidase 8
decreases expression
ISO
Lucanthone results in decreased expression of GPX8 mRNA
CTD
PMID:21148553
NCBI chr 2:46,409,646...46,413,401
Ensembl chr 2:46,409,139...46,413,406
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Gtpbp2
GTP binding protein 2
decreases expression
ISO
Lucanthone results in decreased expression of GTPBP2 mRNA
CTD
PMID:21148553
NCBI chr 9:22,311,532...22,321,405
Ensembl chr 9:22,311,158...22,321,441
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H1f4
H1.4 linker histone, cluster member
decreases expression
ISO
Lucanthone results in decreased expression of H1-4 mRNA
CTD
PMID:21148553
NCBI chr17:41,914,425...41,915,206
Ensembl chr17:41,914,431...41,916,129
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H1f5
H1.5 linker histone, cluster member
decreases expression
ISO
Lucanthone results in decreased expression of H1-5 mRNA
CTD
PMID:21148553
NCBI chr17:47,421,875...47,422,905
Ensembl chr17:47,421,843...47,477,387
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H2ac12
H2A clustered histone 12
decreases expression
ISO
Lucanthone results in decreased expression of H2AC12 mRNA
CTD
PMID:21148553
NCBI chr17:47,182,193...47,182,658
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H2ac21
H2A clustered histone 21
decreases expression
ISO
Lucanthone results in decreased expression of H2AC21 mRNA
CTD
PMID:21148553
NCBI chr 2:186,468,224...186,468,657
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H2ac4
H2A clustered histone 4
decreases expression
ISO
Lucanthone results in decreased expression of H2AC4 mRNA
CTD
PMID:21148553
NCBI chr17:47,495,624...47,496,127
Ensembl chr17:47,495,546...47,496,173
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H2bc8
H2B clustered histone 8
decreases expression
ISO
Lucanthone results in decreased expression of H2BC8 mRNA
CTD
PMID:21148553
NCBI chr17:47,404,405...47,405,155
G
H2bc9
H2B clustered histone 9
decreases expression
ISO
Lucanthone results in decreased expression of H2BC9 mRNA
CTD
PMID:21148553
NCBI chr17:47,166,372...47,174,369
G
H3c13
H3 clustered histone 13
decreases expression
ISO
Lucanthone results in decreased expression of H3C13 mRNA
CTD
PMID:21148553
NCBI chr17:41,959,540...41,960,009
Ensembl chr17:41,958,965...41,960,099
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H4c14
H4 clustered histone 14
decreases expression
ISO
Lucanthone results in decreased expression of H4C2 mRNA
CTD
PMID:21148553
NCBI chr 2:186,520,468...186,520,863
Ensembl chr 4:171,403,627...171,403,938 Ensembl chr17:171,403,627...171,403,938 Ensembl chr17:171,403,627...171,403,938 Ensembl chr17:171,403,627...171,403,938
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H4f3
H1.3 linker histone, cluster member
decreases expression
ISO
Lucanthone results in decreased expression of H1-3 mRNA
CTD
PMID:21148553
NCBI chr17:41,979,562...41,980,341
Ensembl chr17:41,796,116...41,980,485
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Hist1h2bq
histone cluster 1 H2B family member Q
decreases expression
ISO
Lucanthone results in decreased expression of H2BC7 mRNA
CTD
PMID:21148553
NCBI chr17:41,859,955...41,869,889
Ensembl chr17:41,857,231...41,870,107 Ensembl chr17:41,857,231...41,870,107
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Hjurp
Holliday junction recognition protein
decreases expression
ISO
Lucanthone results in decreased expression of HJURP mRNA
CTD
PMID:21148553
NCBI chr 9:96,301,183...96,315,587
Ensembl chr 9:96,302,530...96,315,657
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Hmgb2
high mobility group box 2
decreases expression
ISO
Lucanthone results in decreased expression of HMGB2 mRNA
CTD
PMID:21148553
NCBI chr16:37,721,374...37,723,950
Ensembl chr16:37,721,379...37,723,860
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Hmgcs1
3-hydroxy-3-methylglutaryl-CoA synthase 1
increases expression
ISO
Lucanthone results in increased expression of HMGCS1 mRNA
CTD
PMID:21148553
NCBI chr 2:53,379,457...53,399,807
Ensembl chr 2:53,382,643...53,399,802
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Hmmr
hyaluronan-mediated motility receptor
decreases expression
ISO
Lucanthone results in decreased expression of HMMR mRNA
CTD
PMID:21148553
NCBI chr10:25,635,249...25,665,389
Ensembl chr10:25,635,915...25,665,390
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Icam1
intercellular adhesion molecule 1
increases expression
ISO
Lucanthone results in increased expression of ICAM1 mRNA
CTD
PMID:21148553
NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:27,829,161...27,841,617
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Idi1
isopentenyl-diphosphate delta isomerase 1
increases expression
ISO
Lucanthone results in increased expression of IDI1 mRNA
CTD
PMID:21148553
NCBI chr17:66,539,761...66,547,524
Ensembl chr17:66,539,763...66,547,524
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Ifi30
IFI30, lysosomal thiol reductase
increases expression
ISO
Lucanthone results in increased expression of IFI30 mRNA
CTD
PMID:21148553
NCBI chr16:18,709,570...18,713,635
Ensembl chr16:18,709,563...18,715,711
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Il18
interleukin 18
decreases expression
ISO
Lucanthone results in decreased expression of IL18 mRNA
CTD
PMID:21148553
NCBI chr 8:59,802,072...59,829,275
Ensembl chr 8:59,809,592...59,831,286
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Il24
interleukin 24
increases expression
ISO
Lucanthone results in increased expression of IL24 mRNA
CTD
PMID:21148553
NCBI chr13:44,905,362...44,910,760
Ensembl chr13:44,905,363...44,910,760
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Il6
interleukin 6
increases expression
ISO
Lucanthone results in increased expression of IL6 mRNA
CTD
PMID:21148553
NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610
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Iqgap3
IQ motif containing GTPase activating protein 3
decreases expression
ISO
Lucanthone results in decreased expression of IQGAP3 mRNA
CTD
PMID:21148553
NCBI chr 2:175,840,001...175,881,799
Ensembl chr 2:175,839,949...175,881,797
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Itga3
integrin subunit alpha 3
increases expression
ISO
Lucanthone results in increased expression of ITGA3 mRNA
CTD
PMID:21148553
NCBI chr10:80,486,998...80,522,548
Ensembl chr10:80,486,999...80,518,901
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Kif11
kinesin family member 11
decreases expression
ISO
Lucanthone results in decreased expression of KIF11 mRNA
CTD
PMID:21148553
NCBI chr 1:244,494,916...244,589,250
Ensembl chr 1:244,494,875...244,589,250
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Kif14
kinesin family member 14
decreases expression
ISO
Lucanthone results in decreased expression of KIF14 mRNA
CTD
PMID:21148553
NCBI chr13:50,478,646...50,542,256
Ensembl chr13:50,478,721...50,542,248
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Kif15
kinesin family member 15
decreases expression
ISO
Lucanthone results in decreased expression of KIF15 mRNA
CTD
PMID:21148553
NCBI chr 8:131,479,340...131,550,209
Ensembl chr 8:131,479,337...131,550,202
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Kif20a
kinesin family member 20A
decreases expression
ISO
Lucanthone results in decreased expression of KIF20A mRNA
CTD
PMID:21148553
NCBI chr18:26,504,422...26,512,908
Ensembl chr18:26,504,072...26,512,909
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Kif20b
kinesin family member 20B
decreases expression
ISO
Lucanthone results in decreased expression of KIF20B mRNA
CTD
PMID:21148553
NCBI chr 1:241,840,898...241,896,451
Ensembl chr 1:241,840,987...241,896,451
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Kif22
kinesin family member 22
decreases expression
ISO
Lucanthone results in decreased expression of KIF22 mRNA
CTD
PMID:21148553
NCBI chr 1:191,065,875...191,080,955
Ensembl chr 1:191,065,875...191,080,878
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Kif23
kinesin family member 23
decreases expression
ISO
Lucanthone results in decreased expression of KIF23 mRNA
CTD
PMID:21148553
NCBI chr 8:71,293,439...71,321,911
Ensembl chr 8:71,293,482...71,320,856
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Kif2c
kinesin family member 2C
decreases expression
ISO
Lucanthone results in decreased expression of KIF2C mRNA
CTD
PMID:21148553
NCBI chr 5:135,873,925...135,899,267
Ensembl chr 5:135,873,925...135,899,212
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Kif4a
kinesin family member 4A
decreases expression
ISO
Lucanthone results in decreased expression of KIF4A mRNA
CTD
PMID:21148553
NCBI chr X:69,761,803...69,864,335
Ensembl chr X:69,761,883...69,864,335
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Kifc1
kinesin family member C1
decreases expression
ISO
Lucanthone results in decreased expression of KIFC1 mRNA
CTD
PMID:21148553
NCBI chr20:5,000,929...5,018,967
Ensembl chr20:5,000,648...5,018,988
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Knl1
kinetochore scaffold 1
decreases expression
ISO
Lucanthone results in decreased expression of KNL1 mRNA
CTD
PMID:21148553
NCBI chr 3:126,483,498...126,545,774
Ensembl chr 3:126,483,544...126,545,774
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Lamp3
lysosomal-associated membrane protein 3
decreases expression
ISO
Lucanthone results in decreased expression of LAMP3 mRNA
CTD
PMID:21148553
NCBI chr11:94,657,817...94,726,451
Ensembl chr11:94,661,399...94,726,195
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Lin9
lin-9 DREAM MuvB core complex component
decreases expression
ISO
Lucanthone results in decreased expression of LIN9 mRNA
CTD
PMID:21148553
NCBI chr13:94,906,185...94,951,541
Ensembl chr13:94,906,548...94,951,539
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Lrp1
LDL receptor related protein 1
increases expression
ISO
Lucanthone results in increased expression of LRP1 mRNA
CTD
PMID:21148553
NCBI chr 7:65,265,639...65,346,196
Ensembl chr 7:65,265,639...65,346,196
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Lxn
latexin
increases expression
ISO
Lucanthone results in increased expression of LXN mRNA
CTD
PMID:21148553
NCBI chr 2:154,037,604...154,043,473
Ensembl chr 2:154,037,292...154,043,488
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Mad2l1
mitotic arrest deficient 2 like 1
decreases expression
ISO
Lucanthone results in decreased expression of MAD2L1 mRNA
CTD
PMID:21148553
NCBI chr 4:97,236,419...97,247,603
Ensembl chr 4:97,236,503...97,243,222
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Mboat1
membrane bound O-acyltransferase domain containing 1
decreases expression
ISO
Lucanthone results in decreased expression of MBOAT1 mRNA
CTD
PMID:21148553
NCBI chr17:34,540,032...34,653,705
Ensembl chr17:34,540,041...34,653,698
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Mcm10
minichromosome maintenance 10 replication initiation factor
decreases expression
ISO
Lucanthone results in decreased expression of MCM10 mRNA
CTD
PMID:21148553
NCBI chr17:78,172,049...78,197,644
Ensembl chr17:78,175,398...78,197,636
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Mcm8
minichromosome maintenance 8 homologous recombination repair factor
decreases expression
ISO
Lucanthone results in decreased expression of MCM8 mRNA
CTD
PMID:21148553
NCBI chr 3:140,539,590...140,569,891
Ensembl chr 3:140,539,647...140,569,891
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Melk
maternal embryonic leucine zipper kinase
decreases expression
ISO
Lucanthone results in decreased expression of MELK mRNA
CTD
PMID:21148553
NCBI chr 5:63,336,151...63,396,254
Ensembl chr 5:63,336,106...63,396,247
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Mki67
marker of proliferation Ki-67
decreases expression
ISO
Lucanthone results in decreased expression of MKI67 mRNA
CTD
PMID:21148553
NCBI chr 1:199,926,150...199,952,847
Ensembl chr 1:199,926,150...199,952,593
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Mmp1
matrix metallopeptidase 1
increases expression
ISO
Lucanthone results in increased expression of MMP1 mRNA
CTD
PMID:21148553
NCBI chr 8:12,943,453...12,963,966
Ensembl chr 8:12,943,453...12,963,964
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Mnd1
meiotic nuclear divisions 1
decreases expression
ISO
Lucanthone results in decreased expression of MND1 mRNA
CTD
PMID:21148553
NCBI chr 2:171,731,523...171,794,124
Ensembl chr 2:171,731,523...171,794,095
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Mocos
molybdenum cofactor sulfurase
decreases expression
ISO
Lucanthone results in decreased expression of MOCOS mRNA
CTD
PMID:21148553
NCBI chr18:16,206,402...16,251,928
Ensembl chr18:16,206,402...16,251,928
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Msmo1
methylsterol monooxygenase 1
increases expression
ISO
Lucanthone results in increased expression of MSMO1 mRNA
CTD
PMID:21148553
NCBI chr16:29,747,113...29,764,360
Ensembl chr16:29,747,137...29,764,445
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Mtfr2
mitochondrial fission regulator 2
decreases expression
ISO
Lucanthone results in decreased expression of MTFR2 mRNA
CTD
PMID:21148553
NCBI chr 1:16,942,814...16,958,218
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Mx1
MX dynamin like GTPase 1
increases expression
ISO
Lucanthone results in increased expression of MX1 mRNA
CTD
PMID:21148553
NCBI chr11:50,269,056...50,294,699
Ensembl chr11:50,269,057...50,292,904
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Mybl2
MYB proto-oncogene like 2
decreases expression
ISO
Lucanthone results in decreased expression of MYBL2 mRNA
CTD
PMID:21148553
NCBI chr 3:172,124,765...172,153,221
Ensembl chr 3:172,116,550...172,153,221
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Ncapg
non-SMC condensin I complex, subunit G
decreases expression
ISO
Lucanthone results in decreased expression of NCAPG mRNA
CTD
PMID:21148553
NCBI chr14:69,616,473...69,645,445
Ensembl chr14:69,616,473...69,645,445
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Ncapg2
non-SMC condensin II complex, subunit G2
decreases expression
ISO
Lucanthone results in decreased expression of NCAPG2 mRNA
CTD
PMID:21148553
NCBI chr 6:143,484,651...143,561,850
Ensembl chr 6:143,485,944...143,560,249
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Ncaph
non-SMC condensin I complex, subunit H
decreases expression
ISO
Lucanthone results in decreased expression of NCAPH mRNA
CTD
PMID:21148553
NCBI chr 3:134,825,271...134,852,502
Ensembl chr 3:134,825,271...134,852,502
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Ndc80
NDC80 kinetochore complex component
decreases expression
ISO
Lucanthone results in decreased expression of NDC80 mRNA
CTD
PMID:21148553
NCBI chr 9:118,853,806...118,887,582
Ensembl chr 9:118,853,806...118,887,568
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Nek2
NIMA-related kinase 2
decreases expression
ISO
Lucanthone results in decreased expression of NEK2 mRNA
CTD
PMID:21148553
NCBI chr13:105,936,809...105,950,054
Ensembl chr13:105,936,788...105,950,056
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Nemp1
nuclear envelope integral membrane protein 1
decreases expression
ISO
Lucanthone results in decreased expression of NEMP1 mRNA
CTD
PMID:21148553
NCBI chr 7:65,399,297...65,424,054
Ensembl chr 7:65,399,381...65,424,055
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Niban1
niban apoptosis regulator 1
decreases expression
ISO
Lucanthone results in decreased expression of NIBAN1 mRNA
CTD
PMID:21148553
NCBI chr13:66,224,219...66,377,728
Ensembl chr13:66,224,021...66,377,724
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Nr4a2
nuclear receptor subfamily 4, group A, member 2
increases expression
ISO
Lucanthone results in increased expression of NR4A2 mRNA
CTD
PMID:21148553
NCBI chr 3:62,098,739...62,115,926
Ensembl chr 3:62,098,743...62,106,769
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Nuf2
NUF2 component of NDC80 kinetochore complex
decreases expression
ISO
Lucanthone results in decreased expression of NUF2 mRNA
CTD
PMID:21148553
NCBI chr13:84,226,448...84,290,957
Ensembl chr13:84,226,509...84,255,598
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Nusap1
nucleolar and spindle associated protein 1
decreases expression
ISO
Lucanthone results in decreased expression of NUSAP1 mRNA
CTD
PMID:21148553
NCBI chr 3:127,057,220...127,092,779
Ensembl chr 3:127,057,265...127,087,237
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Orc6
origin recognition complex, subunit 6
decreases expression
ISO
Lucanthone results in decreased expression of ORC6 mRNA
CTD
PMID:21148553
NCBI chr19:37,931,085...37,938,856
Ensembl chr19:37,931,090...37,938,856
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Otub2
OTU deubiquitinase, ubiquitin aldehyde binding 2
increases expression
ISO
Lucanthone results in increased expression of OTUB2 mRNA
CTD
PMID:21148553
NCBI chr 6:128,309,863...128,328,444
Ensembl chr 6:128,299,693...128,328,433
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Pbk
PDZ binding kinase
decreases expression
ISO
Lucanthone results in decreased expression of PBK mRNA
CTD
PMID:21148553
NCBI chr15:44,198,506...44,209,572
Ensembl chr15:44,198,544...44,209,570
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Pclaf
PCNA clamp associated factor
decreases expression
ISO
Lucanthone results in decreased expression of PCLAF mRNA
CTD
PMID:21148553
NCBI chr 8:75,311,028...75,328,108
Ensembl chr 8:75,315,707...75,328,106
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Phgdh
phosphoglycerate dehydrogenase
decreases expression
ISO
Lucanthone results in decreased expression of PHGDH mRNA
CTD
PMID:21148553
NCBI chr 2:188,595,700...188,624,789
Ensembl chr 2:188,595,700...188,624,789
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Plk1
polo-like kinase 1
decreases expression
ISO
Lucanthone results in decreased expression of PLK1 mRNA
CTD
PMID:21148553
NCBI chr 1:186,147,658...186,157,637
Ensembl chr 1:186,147,658...186,157,637
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Plk4
polo-like kinase 4
decreases expression
ISO
Lucanthone results in decreased expression of PLK4 mRNA
CTD
PMID:21148553
NCBI chr 2:125,730,480...125,748,894
Ensembl chr 2:125,730,460...125,748,892
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Pole2
DNA polymerase epsilon 2, accessory subunit
decreases expression
ISO
Lucanthone results in decreased expression of POLE2 mRNA
CTD
PMID:21148553
NCBI chr 6:93,410,713...93,448,782
Ensembl chr 6:93,410,758...93,435,361
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Prc1
protein regulator of cytokinesis 1
decreases expression
ISO
Lucanthone results in decreased expression of PRC1 mRNA
CTD
PMID:21148553
NCBI chr 1:143,659,312...143,681,019
Ensembl chr 1:143,659,481...143,681,012
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Prim1
DNA primase subunit 1
decreases expression
ISO
Lucanthone results in decreased expression of PRIM1 mRNA
CTD
PMID:21148553
NCBI chr 7:1,031,436...1,047,134
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Prr11
proline rich 11
decreases expression
ISO
Lucanthone results in decreased expression of PRR11 mRNA
CTD
PMID:21148553
NCBI chr10:72,396,127...72,440,643
Ensembl chr10:72,398,667...72,418,275
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Psat1
phosphoserine aminotransferase 1
decreases expression
ISO
Lucanthone results in decreased expression of PSAT1 mRNA
CTD
PMID:21148553
NCBI chr 1:222,623,553...222,646,187
Ensembl chr 1:222,623,556...222,655,693
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Psmc3ip
PSMC3 interacting protein
decreases expression
ISO
Lucanthone results in decreased expression of PSMC3IP mRNA
CTD
PMID:21148553
NCBI chr10:86,524,546...86,527,764
Ensembl chr10:86,524,571...86,527,666
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Ptchd4
patched domain containing 4
increases expression
ISO
Lucanthone results in increased expression of PTCHD4 mRNA
CTD
PMID:21148553
NCBI chr 9:25,951,395...26,163,296
Ensembl chr 9:25,959,954...26,163,284
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Pxdn
peroxidasin
increases expression
ISO
Lucanthone results in increased expression of PXDN mRNA
CTD
PMID:21148553
NCBI chr 6:52,308,347...52,385,943
Ensembl chr 6:52,308,364...52,385,942
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Racgap1
Rac GTPase-activating protein 1
decreases expression
ISO
Lucanthone results in decreased expression of RACGAP1 mRNA
CTD
PMID:21148553
NCBI chr 7:132,629,789...132,659,738
Ensembl chr 7:132,620,595...132,659,738
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Rad51
RAD51 recombinase
decreases expression
ISO
Lucanthone results in decreased expression of RAD51 mRNA
CTD
PMID:21148553
NCBI chr 3:126,554,210...126,578,888
Ensembl chr 3:126,554,190...126,579,469
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Rad51ap1
RAD51 associated protein 1
decreases expression
ISO
Lucanthone results in decreased expression of RAD51AP1 mRNA
CTD
PMID:21148553
NCBI chr 4:161,445,610...161,458,661
Ensembl chr 4:161,445,512...161,458,680
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Rrm2
ribonucleotide reductase regulatory subunit M2
decreases expression
ISO
Lucanthone results in decreased expression of RRM2 mRNA
CTD
PMID:21148553
NCBI chr 6:47,044,755...47,075,370
Ensembl chr 6:47,067,690...47,075,370
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Sat1
spermidine/spermine N1-acetyl transferase 1
increases expression
ISO
Lucanthone results in increased expression of SAT1 mRNA
CTD
PMID:21148553
NCBI chr X:44,008,089...44,011,376
Ensembl chr X:44,006,781...44,011,374
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Scube1
signal peptide, CUB domain and EGF like domain containing 1
increases expression
ISO
Lucanthone results in increased expression of SCUBE1 mRNA
CTD
PMID:21148553
NCBI chr 7:116,639,027...116,760,986
Ensembl chr 7:116,642,231...116,760,944
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Sectm1b
secreted and transmembrane 1B
increases expression
ISO
Lucanthone results in increased expression of SECTM1 mRNA
CTD
PMID:21148553
NCBI chr10:106,822,397...106,832,105
Ensembl chr10:106,822,397...106,832,104
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Serpinb2
serpin family B member 2
increases expression
ISO
Lucanthone results in increased expression of SERPINB2 mRNA
CTD
PMID:21148553
NCBI chr13:24,051,933...24,065,032
Ensembl chr13:24,056,021...24,065,031
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Sgo1
shugoshin 1
decreases expression
ISO
Lucanthone results in decreased expression of SGO1 mRNA
CTD
PMID:21148553
NCBI chr 9:6,908,661...6,943,483
Ensembl chr 9:6,908,661...6,924,415
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Sgo2
shugoshin 2
decreases expression
ISO
Lucanthone results in decreased expression of SGO2 mRNA
CTD
PMID:21148553
NCBI chr 9:67,032,083...67,067,439
Ensembl chr 9:67,042,833...67,068,152
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Shc4
SHC adaptor protein 4
increases expression
ISO
Lucanthone results in increased expression of SHC4 mRNA
CTD
PMID:21148553
NCBI chr 3:133,334,026...133,428,404
Ensembl chr 3:133,334,034...133,427,826
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Shcbp1
SHC binding and spindle associated 1
decreases expression
ISO
Lucanthone results in decreased expression of SHCBP1 mRNA
CTD
PMID:21148553
NCBI chr16:91,373,843...91,405,409
Ensembl chr16:91,373,871...91,405,409
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Slc1a4
solute carrier family 1 member 4
decreases expression
ISO
Lucanthone results in decreased expression of SLC1A4 mRNA
CTD
PMID:21148553
NCBI chr14:98,718,646...98,761,672
Ensembl chr14:98,730,450...98,761,790
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Smc4
structural maintenance of chromosomes 4
decreases expression
ISO
Lucanthone results in decreased expression of SMC4 mRNA
CTD
PMID:21148553
NCBI chr 2:155,550,262...155,578,695
Ensembl chr 2:155,550,262...155,581,937
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Spag5
sperm associated antigen 5
decreases expression
ISO
Lucanthone results in decreased expression of SPAG5 mRNA
CTD
PMID:21148553
NCBI chr10:63,693,300...63,714,813
Ensembl chr10:63,696,466...63,714,811
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Spata18
spermatogenesis associated 18
increases expression
ISO
Lucanthone results in increased expression of SPATA18 mRNA
CTD
PMID:21148553
NCBI chr14:34,885,995...34,912,704
Ensembl chr14:34,885,995...34,912,736
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Spc25
SPC25 component of NDC80 kinetochore complex
decreases expression
ISO
Lucanthone results in decreased expression of SPC25 mRNA
CTD
PMID:21148553
NCBI chr 3:74,337,872...74,396,825
Ensembl chr 3:74,383,548...74,396,718
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Spdl1
spindle apparatus coiled-coil protein 1
decreases expression
ISO
Lucanthone results in decreased expression of SPDL1 mRNA
CTD
PMID:21148553
NCBI chr10:19,773,456...19,798,341
Ensembl chr10:19,773,457...19,798,297
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Stmn1
stathmin 1
decreases expression
ISO
Lucanthone results in decreased expression of STMN1 mRNA
CTD
PMID:21148553
NCBI chr 5:151,964,308...151,970,843
Ensembl chr 5:151,964,351...151,970,842
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Sulf2
sulfatase 2
increases expression
ISO
Lucanthone results in increased expression of SULF2 mRNA
CTD
PMID:21148553
NCBI chr 3:175,241,322...175,323,808
Ensembl chr 3:175,241,322...175,323,651
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Tcp11l2
t-complex 11 like 2
increases expression
ISO
Lucanthone results in increased expression of TCP11L2 mRNA
CTD
PMID:21148553
NCBI chr 7:21,037,955...21,072,857
Ensembl chr 7:21,037,958...21,064,681
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Tfpi2
tissue factor pathway inhibitor 2
increases expression
ISO
Lucanthone results in increased expression of TFPI2 mRNA
CTD
PMID:21148553
NCBI chr 4:32,936,462...32,941,385
Ensembl chr 4:32,936,854...32,941,426
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Tiparp
TCDD-inducible poly(ADP-ribose) polymerase
increases expression
ISO
Lucanthone results in increased expression of TIPARP mRNA
CTD
PMID:21148553
NCBI chr 2:152,063,769...152,090,414
Ensembl chr 2:152,063,751...152,090,406
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Tmem45a
transmembrane protein 45A
increases expression
ISO
Lucanthone results in increased expression of TMEM45A mRNA
CTD
PMID:21148553
NCBI chr11:57,181,686...57,268,630
Ensembl chr11:57,182,785...57,282,722
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Tnfsf15
TNF superfamily member 15
increases expression
ISO
Lucanthone results in increased expression of TNFSF15 mRNA
CTD
PMID:21148553
NCBI chr 5:82,150,376...82,171,743
Ensembl chr 5:82,150,376...82,171,882
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Top2a
DNA topoisomerase II alpha
decreases expression
ISO
Lucanthone results in decreased expression of TOP2A mRNA
CTD
PMID:21148553
NCBI chr10:84,441,954...84,473,093
Ensembl chr10:84,441,954...84,473,366
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Tp53i3
tumor protein p53 inducible protein 3
increases expression
ISO
Lucanthone results in increased expression of TP53I3 mRNA
CTD
PMID:21148553
NCBI chr 6:33,537,779...33,545,204
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Tp53inp1
tumor protein p53 inducible nuclear protein 1
increases expression
ISO
Lucanthone results in increased expression of TP53INP1 mRNA
CTD
PMID:21148553
NCBI chr 5:29,051,267...29,069,486
Ensembl chr 5:29,051,264...29,069,484
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Tpx2
TPX2, microtubule nucleation factor
decreases expression
ISO
Lucanthone results in decreased expression of TPX2 mRNA
CTD
PMID:21148553
NCBI chr 3:161,778,709...161,820,941
Ensembl chr 3:161,778,742...161,820,724
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Ttk
Ttk protein kinase
decreases expression
ISO
Lucanthone results in decreased expression of TTK mRNA
CTD
PMID:21148553
NCBI chr 8:93,632,678...93,672,664
Ensembl chr 8:93,634,319...93,672,664
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Ube2t
ubiquitin-conjugating enzyme E2T
decreases expression
ISO
Lucanthone results in decreased expression of UBE2T mRNA
CTD
PMID:21148553
NCBI chr13:48,955,166...48,965,668
Ensembl chr13:48,955,183...48,966,646
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Wdr76
WD repeat domain 76
decreases expression
ISO
Lucanthone results in decreased expression of WDR76 mRNA
CTD
PMID:21148553
NCBI chr 3:128,910,500...128,945,241
Ensembl chr 3:128,910,503...128,945,239
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Xrcc2
X-ray repair cross complementing 2
decreases expression
ISO
Lucanthone results in decreased expression of XRCC2 mRNA
CTD
PMID:21148553
NCBI chr 4:10,157,130...10,237,089
Ensembl chr 4:10,157,800...10,176,407
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Zwint
ZW10 interacting kinetochore protein
decreases expression
ISO
Lucanthone results in decreased expression of ZWINT mRNA
CTD
PMID:21148553
NCBI chr20:15,502,559...15,953,701
Ensembl chr20:15,937,396...15,953,203
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Nr1i2
nuclear receptor subfamily 1, group I, member 2
increases activity
ISO
Hycanthone results in increased activity of NR1I2 protein
CTD
PMID:25455453
NCBI chr11:75,965,717...76,006,733
Ensembl chr11:75,965,632...76,002,380
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Tp53
tumor protein p53
affects activity
ISO
Hycanthone affects the activity of TP53 protein
CTD
PMID:35435491
NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299
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