|
G |
Aif1 |
allograft inflammatory factor 1 |
multiple interactions |
ISO |
corilagin inhibits the reaction [Morphine results in increased expression of AIF1 protein]; TLR2 protein inhibits the reaction [corilagin inhibits the reaction [Morphine results in increased expression of AIF1 protein]]; Tunicamycin inhibits the reaction [corilagin inhibits the reaction [Morphine results in increased expression of AIF1 protein]] |
CTD |
PMID:37394652 |
|
NCBI chr20:3,651,435...3,657,341
|
|
G |
Akt1 |
AKT serine/threonine kinase 1 |
multiple interactions decreases expression |
EXP ISO |
corilagin inhibits the reaction [Doxorubicin results in increased expression of AKT1 protein]; corilagin inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of AKT1 mRNA] corilagin results in decreased expression of AKT1 protein |
CTD |
PMID:34369273 PMID:34605098 PMID:35084093 PMID:35103375 |
|
NCBI chr 6:137,534,810...137,555,131
|
|
G |
Atf4 |
activating transcription factor 4 |
multiple interactions |
ISO |
corilagin inhibits the reaction [Morphine results in increased expression of ATF4 protein]; TLR2 protein inhibits the reaction [corilagin inhibits the reaction [Morphine results in increased expression of ATF4 protein]] |
CTD |
PMID:37394652 |
|
NCBI chr 7:113,684,681...113,686,739
|
|
G |
Bax |
BCL2 associated X, apoptosis regulator |
multiple interactions |
EXP |
corilagin inhibits the reaction [Doxorubicin results in increased expression of BAX protein]; corilagin inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of BAX protein] |
CTD |
PMID:34605098 PMID:35103375 |
|
NCBI chr 1:105,076,472...105,081,906
|
|
G |
Bcl2 |
BCL2, apoptosis regulator |
multiple interactions |
EXP |
corilagin inhibits the reaction [Doxorubicin results in decreased expression of BCL2 protein]; corilagin inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of BCL2 protein] |
CTD |
PMID:34605098 PMID:35103375 |
|
NCBI chr13:23,204,464...23,366,900
|
|
G |
Bsg |
basigin |
multiple interactions |
EXP |
corilagin inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of BSG mRNA] |
CTD |
PMID:35103375 |
|
NCBI chr 7:10,643,788...10,651,005
|
|
G |
Casp3 |
caspase 3 |
multiple interactions |
EXP ISO |
corilagin inhibits the reaction [Doxorubicin results in increased expression of CASP3 protein]; corilagin inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of CASP3 protein] corilagin inhibits the reaction [Morphine results in increased cleavage of CASP3 protein]; TLR2 protein inhibits the reaction [corilagin inhibits the reaction [Morphine results in increased cleavage of CASP3 protein]]; Tunicamycin inhibits the reaction [corilagin inhibits the reaction [Morphine results in increased cleavage of CASP3 protein]] |
CTD |
PMID:34605098 PMID:35103375 PMID:37394652 |
|
NCBI chr16:52,395,539...52,413,794
|
|
G |
Casp9 |
caspase 9 |
multiple interactions |
EXP |
corilagin inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of CASP9 protein] |
CTD |
PMID:35103375 |
|
|
|
G |
Cat |
catalase |
multiple interactions |
EXP ISO |
corilagin inhibits the reaction [Doxorubicin results in decreased activity of CAT protein]; corilagin inhibits the reaction [Methylnitronitrosoguanidine results in decreased activity of CAT protein]; corilagin inhibits the reaction [Streptozocin results in decreased activity of CAT protein] corilagin inhibits the reaction [TNFSF11 protein results in decreased expression of CAT mRNA] |
CTD |
PMID:30582900 PMID:34605098 PMID:35103375 PMID:35307913 |
|
NCBI chr 3:110,297,340...110,329,526
|
|
G |
Ddit3 |
DNA-damage inducible transcript 3 |
multiple interactions |
ISO |
corilagin inhibits the reaction [Morphine results in increased expression of DDIT3 protein]; TLR2 protein inhibits the reaction [corilagin inhibits the reaction [Morphine results in increased expression of DDIT3 protein]] |
CTD |
PMID:37394652 |
|
NCBI chr 7:65,001,695...65,006,517
|
|
G |
Eif2ak3 |
eukaryotic translation initiation factor 2 alpha kinase 3 |
multiple interactions |
ISO |
corilagin inhibits the reaction [Morphine results in increased phosphorylation of EIF2AK3 protein]; TLR2 protein inhibits the reaction [corilagin inhibits the reaction [Morphine results in increased phosphorylation of EIF2AK3 protein]] |
CTD |
PMID:37394652 |
|
NCBI chr 4:104,363,838...104,425,271
|
|
G |
Fabp3 |
fatty acid binding protein 3 |
multiple interactions |
EXP |
corilagin inhibits the reaction [Doxorubicin results in increased expression of FABP3 protein] |
CTD |
PMID:34369273 |
|
NCBI chr 5:142,651,962...142,658,707
|
|
G |
Fos |
Fos proto-oncogene, AP-1 transcription factor subunit |
multiple interactions |
ISO |
corilagin inhibits the reaction [TNFSF11 protein results in increased expression of FOS mRNA]; corilagin inhibits the reaction [TNFSF11 protein results in increased expression of FOS protein] |
CTD |
PMID:35307913 |
|
NCBI chr 6:110,852,188...110,855,054
|
|
G |
Gsr |
glutathione-disulfide reductase |
multiple interactions |
ISO |
[corilagin co-treated with TNFSF11 protein] results in increased expression of GSR mRNA |
CTD |
PMID:35307913 |
|
NCBI chr16:65,185,574...65,228,742
|
|
G |
Hif1a |
hypoxia inducible factor 1 subunit alpha |
multiple interactions |
EXP |
corilagin inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of HIF1A mRNA] |
CTD |
PMID:35103375 |
|
NCBI chr 6:98,357,788...98,405,068
|
|
G |
Hmgb1 |
high mobility group box 1 |
multiple interactions |
EXP |
corilagin inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of HMGB1 mRNA] |
CTD |
PMID:35103375 |
|
NCBI chr12:11,009,236...11,015,941
|
|
G |
Hmgcr |
3-hydroxy-3-methylglutaryl-CoA reductase |
multiple interactions |
EXP |
corilagin inhibits the reaction [Doxorubicin results in increased activity of HMGCR protein] |
CTD |
PMID:34605098 |
|
NCBI chr 2:29,732,163...29,754,276
|
|
G |
Hmox1 |
heme oxygenase 1 |
multiple interactions |
ISO |
corilagin inhibits the reaction [TNFSF11 protein results in decreased expression of HMOX1 protein]; tin protoporphyrin IX inhibits the reaction [corilagin inhibits the reaction [TNFSF11 protein results in decreased expression of HMOX1 protein]] |
CTD |
PMID:35307913 |
|
NCBI chr19:13,452,365...13,479,823
|
|
G |
Hspa5 |
heat shock protein family A (Hsp70) member 5 |
multiple interactions |
ISO |
corilagin inhibits the reaction [Morphine results in increased expression of HSPA5 protein]; TLR2 protein inhibits the reaction [corilagin inhibits the reaction [Morphine results in increased expression of HSPA5 protein]] |
CTD |
PMID:37394652 |
|
NCBI chr 3:38,453,016...38,457,475
|
|
G |
Il1b |
interleukin 1 beta |
multiple interactions |
ISO |
corilagin inhibits the reaction [Morphine results in increased expression of IL1B protein]; TLR2 protein inhibits the reaction [corilagin inhibits the reaction [Morphine results in increased expression of IL1B protein]]; Tunicamycin inhibits the reaction [corilagin inhibits the reaction [Morphine results in increased expression of IL1B protein]] |
CTD |
PMID:37394652 |
|
NCBI chr 3:137,030,200...137,036,581
|
|
G |
Il6 |
interleukin 6 |
multiple interactions decreases expression |
EXP ISO |
corilagin inhibits the reaction [Doxorubicin results in increased expression of IL6 protein] corilagin results in decreased expression of IL6 protein corilagin inhibits the reaction [Morphine results in increased expression of IL6 protein]; TLR2 protein inhibits the reaction [corilagin inhibits the reaction [Morphine results in increased expression of IL6 protein]]; Tunicamycin inhibits the reaction [corilagin inhibits the reaction [Morphine results in increased expression of IL6 protein]] |
CTD |
PMID:34369273 PMID:34605098 PMID:35084093 PMID:37394652 |
|
NCBI chr 4:5,889,999...5,894,575
|
|
G |
Ins1 |
insulin 1 |
multiple interactions |
EXP |
corilagin inhibits the reaction [Streptozocin results in increased secretion of INS1 protein] |
CTD |
PMID:30582900 |
|
NCBI chr 1:261,186,119...261,186,686
|
|
G |
Ldha |
lactate dehydrogenase A |
multiple interactions |
EXP |
corilagin inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of LDHA mRNA] |
CTD |
PMID:35103375 |
|
NCBI chr 1:97,371,823...97,381,247
|
|
G |
Mb |
myoglobin |
multiple interactions |
EXP |
corilagin inhibits the reaction [Doxorubicin results in increased expression of MB protein] |
CTD |
PMID:34369273 |
|
NCBI chr 7:110,640,511...110,647,742
|
|
G |
Nfatc1 |
nuclear factor of activated T-cells 1 |
multiple interactions |
ISO |
corilagin inhibits the reaction [TNFSF11 protein results in increased expression of NFATC1 mRNA]; corilagin inhibits the reaction [TNFSF11 protein results in increased expression of NFATC1 protein] |
CTD |
PMID:35307913 |
|
NCBI chr18:76,321,386...76,430,997
|
|
G |
Nfe2l2 |
NFE2 like bZIP transcription factor 2 |
multiple interactions |
ISO |
corilagin inhibits the reaction [TNFSF11 protein results in decreased expression of NFE2L2 mRNA] |
CTD |
PMID:35307913 |
|
NCBI chr 3:81,001,529...81,031,165
|
|
G |
Nfkb1 |
nuclear factor kappa B subunit 1 |
decreases expression |
ISO |
corilagin results in decreased expression of NFKB1 protein |
CTD |
PMID:35084093 |
|
NCBI chr 2:226,689,745...226,805,897
|
|
G |
Nlrp3 |
NLR family, pyrin domain containing 3 |
multiple interactions |
ISO |
corilagin inhibits the reaction [Morphine results in increased expression of NLRP3 protein]; TLR2 protein inhibits the reaction [corilagin inhibits the reaction [Morphine results in increased expression of NLRP3 protein]]; Tunicamycin inhibits the reaction [corilagin inhibits the reaction [Morphine results in increased expression of NLRP3 protein]] |
CTD |
PMID:37394652 |
|
NCBI chr10:44,826,299...44,853,373
|
|
G |
Nos2 |
nitric oxide synthase 2 |
decreases expression multiple interactions |
ISO |
corilagin results in decreased expression of NOS2 protein corilagin inhibits the reaction [Morphine results in increased expression of NOS2 protein]; TLR2 protein inhibits the reaction [corilagin inhibits the reaction [Morphine results in increased expression of NOS2 protein]]; Tunicamycin inhibits the reaction [corilagin inhibits the reaction [Morphine results in increased expression of NOS2 protein]] |
CTD |
PMID:35084093 PMID:37394652 |
|
NCBI chr10:64,313,335...64,349,221
|
|
G |
Nppb |
natriuretic peptide B |
multiple interactions |
EXP |
corilagin inhibits the reaction [Doxorubicin results in increased expression of NPPB protein] |
CTD |
PMID:34369273 |
|
NCBI chr 5:163,699,955...163,701,314
|
|
G |
Nr1h4 |
nuclear receptor subfamily 1, group H, member 4 |
multiple interactions |
EXP |
corilagin inhibits the reaction [1-naphthyl isothiocyanate decreases expression of nr1h4 mRNA and protein in rat liver]; corilagin increases expression of nr1h4 mRNA and protein in rat embryonic liver cells |
RGD |
PMID:29235094 |
RGD:15042872 |
NCBI chr 7:25,733,471...25,829,440
|
|
G |
Pik3cg |
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma |
multiple interactions |
EXP |
corilagin inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of PIK3CG mRNA] |
CTD |
PMID:35103375 |
|
NCBI chr 6:54,494,247...54,529,563
|
|
G |
Pparg |
peroxisome proliferator-activated receptor gamma |
multiple interactions |
EXP |
corilagin inhibits the reaction [Doxorubicin results in increased expression of PPARG protein] |
CTD |
PMID:34605098 |
|
NCBI chr 4:150,095,743...150,221,104
|
|
G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
decreases expression multiple interactions |
ISO |
corilagin results in decreased expression of PTGS2 protein corilagin inhibits the reaction [Morphine results in increased expression of PTGS2 protein]; TLR2 protein inhibits the reaction [corilagin inhibits the reaction [Morphine results in increased expression of PTGS2 protein]]; Tunicamycin inhibits the reaction [corilagin inhibits the reaction [Morphine results in increased expression of PTGS2 protein]] |
CTD |
PMID:35084093 PMID:37394652 |
|
NCBI chr13:64,714,063...64,722,320
|
|
G |
Pycard |
PYD and CARD domain containing |
multiple interactions |
ISO |
corilagin inhibits the reaction [Morphine results in increased expression of PYCARD protein]; TLR2 protein inhibits the reaction [corilagin inhibits the reaction [Morphine results in increased expression of PYCARD protein]]; Tunicamycin inhibits the reaction [corilagin inhibits the reaction [Morphine results in increased expression of PYCARD protein]] |
CTD |
PMID:37394652 |
|
NCBI chr 1:192,032,124...192,033,419
|
|
G |
Slc16a3 |
solute carrier family 16 member 3 |
multiple interactions |
EXP |
corilagin inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of SLC16A3 mRNA] |
CTD |
PMID:35103375 |
|
NCBI chr10:106,212,679...106,222,564
|
|
G |
Tgfb1 |
transforming growth factor, beta 1 |
multiple interactions |
EXP |
corilagin inhibits the reaction [Doxorubicin results in increased expression of TGFB1 protein] |
CTD |
PMID:34369273 |
|
NCBI chr 1:90,324,312...90,340,627
|
|
G |
Tlr2 |
toll-like receptor 2 |
multiple interactions |
ISO |
corilagin inhibits the reaction [Morphine results in increased expression of TLR2 mRNA]; corilagin inhibits the reaction [Morphine results in increased expression of TLR2 protein]; TLR2 protein inhibits the reaction [corilagin inhibits the reaction [Morphine results in increased cleavage of CASP3 protein]]; TLR2 protein inhibits the reaction [corilagin inhibits the reaction [Morphine results in increased expression of AIF1 protein]]; TLR2 protein inhibits the reaction [corilagin inhibits the reaction [Morphine results in increased expression of ATF4 protein]]; TLR2 protein inhibits the reaction [corilagin inhibits the reaction [Morphine results in increased expression of DDIT3 protein]]; TLR2 protein inhibits the reaction [corilagin inhibits the reaction [Morphine results in increased expression of HSPA5 protein]]; TLR2 protein inhibits the reaction [corilagin inhibits the reaction [Morphine results in increased expression of IL1B protein]]; TLR2 protein inhibits the reaction [corilagin inhibits the reaction [Morphine results in increased expression of IL6 protein]]; TLR2 protein inhibits the reaction [corilagin inhibits the reaction [Morphine results in increased expression of NLRP3 protein]]; TLR2 protein inhibits the reaction [corilagin inhibits the reaction [Morphine results in increased expression of NOS2 protein]]; TLR2 protein inhibits the reaction [corilagin inhibits the reaction [Morphine results in increased expression of PTGS2 protein]]; TLR2 protein inhibits the reaction [corilagin inhibits the reaction [Morphine results in increased expression of PYCARD protein]]; TLR2 protein inhibits the reaction [corilagin inhibits the reaction [Morphine results in increased expression of TNF protein]]; TLR2 protein inhibits the reaction [corilagin inhibits the reaction [Morphine results in increased phosphorylation of EIF2AK3 protein]] |
CTD |
PMID:37394652 |
|
NCBI chr 2:171,499,189...171,504,831
|
|
G |
Tnf |
tumor necrosis factor |
decreases secretion multiple interactions decreases expression |
ISO EXP |
corilagin results in decreased secretion of TNF protein corilagin inhibits the reaction [Doxorubicin results in increased expression of TNF protein] corilagin results in decreased expression of TNF protein corilagin inhibits the reaction [Morphine results in increased expression of TNF protein]; TLR2 protein inhibits the reaction [corilagin inhibits the reaction [Morphine results in increased expression of TNF protein]]; Tunicamycin inhibits the reaction [corilagin inhibits the reaction [Morphine results in increased expression of TNF protein]] |
CTD |
PMID:12628509 PMID:34369273 PMID:34605098 PMID:35084093 PMID:37394652 |
|
NCBI chr20:3,626,685...3,629,303
|
|
G |
Tnfsf11 |
TNF superfamily member 11 |
multiple interactions |
ISO |
[corilagin co-treated with TNFSF11 protein] results in increased expression of GSR mRNA; corilagin inhibits the reaction [TNFSF11 protein results in decreased expression of CAT mRNA]; corilagin inhibits the reaction [TNFSF11 protein results in decreased expression of HMOX1 protein]; corilagin inhibits the reaction [TNFSF11 protein results in decreased expression of NFE2L2 mRNA]; corilagin inhibits the reaction [TNFSF11 protein results in increased expression of FOS mRNA]; corilagin inhibits the reaction [TNFSF11 protein results in increased expression of FOS protein]; corilagin inhibits the reaction [TNFSF11 protein results in increased expression of NFATC1 mRNA]; corilagin inhibits the reaction [TNFSF11 protein results in increased expression of NFATC1 protein]; tin protoporphyrin IX inhibits the reaction [corilagin inhibits the reaction [TNFSF11 protein results in decreased expression of HMOX1 protein]] |
CTD |
PMID:35307913 |
|
NCBI chr15:60,083,008...60,114,479
|
|
G |
Tnni3 |
troponin I3, cardiac type |
multiple interactions |
EXP |
corilagin inhibits the reaction [Doxorubicin results in increased expression of TNNI3 protein] |
CTD |
PMID:34369273 |
|
NCBI chr 1:78,342,571...78,346,255
|
|