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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:trimethaphan
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Accession:CHEBI:9728 term browser browse the term
Definition:A complex heterocyclic sulfonium compound with an imidazolium core, used to treat hypertension.
Synonyms:exact_synonym: 1,3-dibenzyl-2-oxodecahydrothieno[1',2':1,2]thieno[3,4-d]imidazol-5-ium
 related_synonym: Formula=C22H25N2OS;   InChI=1S/C22H25N2OS/c25-22-23(14-17-8-3-1-4-9-17)19-16-26-13-7-12-20(26)21(19)24(22)15-18-10-5-2-6-11-18/h1-6,8-11,19-21H,7,12-16H2/q+1;   InChIKey=CHQOEHPMXSHGCL-UHFFFAOYSA-N;   SMILES=O=C1N(Cc2ccccc2)C2C[S+]3CCCC3C2N1Cc1ccccc1;   Trimetaphan;   Trimetaphanum
 xref: CAS:7187-66-8;   DrugBank:DB01116;   Drug_Central:2752;   KEGG:C07174
 xref_mesh: MESH:D014294



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trimethaphan term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Spn sialophorin decreases response to substance ISO SPN protein results in decreased susceptibility to Trimethaphan CTD PMID:18711009 NCBI chr 1:181,746,937...181,759,564
Ensembl chr 1:181,746,429...181,759,628
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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19795
    role 19746
      application 19492
        pharmaceutical 19351
          adjuvant 1776
            anaesthesia adjuvant 213
              trimethaphan 1
                trimethaphan camsylate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19795
    subatomic particle 19794
      composite particle 19794
        hadron 19794
          baryon 19794
            nucleon 19794
              atomic nucleus 19794
                atom 19794
                  main group element atom 19693
                    p-block element atom 19693
                      p-block molecular entity 19693
                        chalcogen molecular entity 19445
                          sulfur molecular entity 16418
                            sulfonium compound 85
                              trimethaphan 1
                                trimethaphan camsylate 0
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