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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:trimethaphan
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Accession:CHEBI:9728 term browser browse the term
Definition:A complex heterocyclic sulfonium compound with an imidazolium core, used to treat hypertension.
Synonyms:exact_synonym: 1,3-dibenzyl-2-oxodecahydrothieno[1',2':1,2]thieno[3,4-d]imidazol-5-ium
 related_synonym: Formula=C22H25N2OS;   InChI=1S/C22H25N2OS/c25-22-23(14-17-8-3-1-4-9-17)19-16-26-13-7-12-20(26)21(19)24(22)15-18-10-5-2-6-11-18/h1-6,8-11,19-21H,7,12-16H2/q+1;   InChIKey=CHQOEHPMXSHGCL-UHFFFAOYSA-N;   SMILES=O=C1N(Cc2ccccc2)C2C[S+]3CCCC3C2N1Cc1ccccc1;   Trimetaphan;   Trimetaphanum
 xref: CAS:7187-66-8;   DrugBank:DB01116;   Drug_Central:2752;   KEGG:C07174
 xref_mesh: MESH:D014294



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trimethaphan term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Spn sialophorin decreases response to substance ISO SPN protein results in decreased susceptibility to Trimethaphan CTD PMID:18711009 NCBI chr 1:181,746,937...181,759,564
Ensembl chr 1:181,746,429...181,759,628
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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19918
    role 19894
      application 19729
        pharmaceutical 19565
          adjuvant 4699
            anaesthesia adjuvant 218
              trimethaphan 1
                trimethaphan camsylate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19918
    subatomic particle 19916
      composite particle 19916
        hadron 19916
          baryon 19916
            nucleon 19916
              atomic nucleus 19916
                atom 19916
                  main group element atom 19866
                    p-block element atom 19866
                      p-block molecular entity 19866
                        chalcogen molecular entity 19612
                          sulfur molecular entity 17743
                            sulfonium compound 94
                              trimethaphan 1
                                trimethaphan camsylate 0
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