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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:trimethaphan
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Accession:CHEBI:9728 term browser browse the term
Definition:A complex heterocyclic sulfonium compound with an imidazolium core, used to treat hypertension.
Synonyms:exact_synonym: 1,3-dibenzyl-2-oxodecahydrothieno[1',2':1,2]thieno[3,4-d]imidazol-5-ium
 related_synonym: Formula=C22H25N2OS;   InChI=1S/C22H25N2OS/c25-22-23(14-17-8-3-1-4-9-17)19-16-26-13-7-12-20(26)21(19)24(22)15-18-10-5-2-6-11-18/h1-6,8-11,19-21H,7,12-16H2/q+1;   InChIKey=CHQOEHPMXSHGCL-UHFFFAOYSA-N;   SMILES=O=C1N(Cc2ccccc2)C2C[S+]3CCCC3C2N1Cc1ccccc1;   Trimetaphan;   Trimetaphanum
 xref: CAS:7187-66-8;   DrugBank:DB01116;   Drug_Central:2752;   KEGG:C07174
 xref_mesh: MESH:D014294


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trimethaphan term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Spn sialophorin decreases response to substance ISO SPN protein results in decreased susceptibility to Trimethaphan CTD PMID:18711009 NCBI chr 1:198,572,999...198,585,664
Ensembl chr 1:198,572,999...198,577,226
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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19875
    role 19825
      application 19494
        pharmaceutical 19364
          adjuvant 1774
            anaesthesia adjuvant 213
              trimethaphan 1
                trimethaphan camsylate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19875
    subatomic particle 19873
      composite particle 19873
        hadron 19873
          baryon 19873
            nucleon 19873
              atomic nucleus 19873
                atom 19873
                  main group element atom 19763
                    p-block element atom 19763
                      p-block molecular entity 19763
                        chalcogen molecular entity 19454
                          sulfur molecular entity 16315
                            sulfonium compound 85
                              trimethaphan 1
                                trimethaphan camsylate 0
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