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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:trimethaphan
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Accession:CHEBI:9728 term browser browse the term
Definition:A complex heterocyclic sulfonium compound with an imidazolium core, used to treat hypertension.
Synonyms:exact_synonym: 1,3-dibenzyl-2-oxodecahydrothieno[1',2':1,2]thieno[3,4-d]imidazol-5-ium
 related_synonym: Formula=C22H25N2OS;   InChI=1S/C22H25N2OS/c25-22-23(14-17-8-3-1-4-9-17)19-16-26-13-7-12-20(26)21(19)24(22)15-18-10-5-2-6-11-18/h1-6,8-11,19-21H,7,12-16H2/q+1;   InChIKey=CHQOEHPMXSHGCL-UHFFFAOYSA-N;   SMILES=O=C1N(Cc2ccccc2)C2C[S+]3CCCC3C2N1Cc1ccccc1;   Trimetaphan;   Trimetaphanum
 xref: CAS:7187-66-8;   DrugBank:DB01116;   Drug_Central:2752;   KEGG:C07174
 xref_mesh: MESH:D014294


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trimethaphan term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Spn sialophorin decreases response to substance ISO SPN protein results in decreased susceptibility to Trimethaphan CTD PMID:18711009 NCBI chr 1:181,746,937...181,759,564
Ensembl chr 1:181,746,429...181,759,628 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19812
    role 19784
      application 19615
        pharmaceutical 19493
          adjuvant 4660
            anaesthesia adjuvant 218
              trimethaphan 1
                trimethaphan camsylate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19812
    subatomic particle 19810
      composite particle 19810
        hadron 19810
          baryon 19810
            nucleon 19810
              atomic nucleus 19810
                atom 19810
                  main group element atom 19755
                    p-block element atom 19755
                      p-block molecular entity 19755
                        chalcogen molecular entity 19543
                          sulfur molecular entity 17565
                            sulfonium compound 91
                              trimethaphan 1
                                trimethaphan camsylate 0
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