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ONTOLOGY REPORT - ANNOTATIONS


Term:acemetacin
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Accession:CHEBI:31162 term browser browse the term
Definition:A carboxylic ester that is the carboxymethyl ester of indometacin. A non-steroidal anti-inflammatory drug, it is used in the treatment of rheumatoid arthritis, osteoarthritis, and low back pain, as well as for postoperative pain and inflammation. Its activity is due to both acemetacin and its major metabolite, indometacin.
Synonyms:exact_synonym: {2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetoxy}acetic acid
 related_synonym: Acemix;   Emflex;   Formula=C21H18ClNO6;   InChI=1S/C21H18ClNO6/c1-12-16(10-20(26)29-11-19(24)25)17-9-15(28-2)7-8-18(17)23(12)21(27)13-3-5-14(22)6-4-13/h3-9H,10-11H2,1-2H3,(H,24,25);   InChIKey=FSQKKOOTNAMONP-UHFFFAOYSA-N;   K-708;   Rantudil;   SMILES=COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(=O)OCC(O)=O)c2c1;   Solart;   TV-1322;   TVX 3322;   acemetacina;   acemetacine;   acemetacinum;   indometacin carboxymethyl ester;   indometacin glycolic ester;   indomethacin carboxymethyl ester;   indomethacin glycolic ester
 xref: CAS:53164-05-9 "ChemIDplus";   Drug_Central:47 "DrugCentral";   KEGG:D01582;   LINCS:LSM-5753
 xref_mesh: MESH:C026784
 xref: Patent:DE2234651;   Patent:US3910952;   Reaxys:501672 "Reaxys";   Wikipedia:Acemetacin


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acemetacin term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Glo1 glyoxalase 1 JBrowse link 20 9,273,589 9,291,608 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19669
    role 19613
      biological role 19611
        xenobiotic 18178
          indometacin 3157
            acemetacin 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19669
    subatomic particle 19665
      composite particle 19665
        hadron 19665
          baryon 19665
            nucleon 19665
              atomic nucleus 19665
                atom 19665
                  main group element atom 19545
                    p-block element atom 19545
                      carbon group element atom 19428
                        carbon atom 19420
                          organic molecular entity 19420
                            organic group 18343
                              organic divalent group 18334
                                organodiyl group 18334
                                  carbonyl group 18222
                                    carbonyl compound 18222
                                      carboxylic acid 17923
                                        carboacyl group 16943
                                          univalent carboacyl group 16943
                                            carbamoyl group 16622
                                              carboxamide 16622
                                                N-acylindole 3157
                                                  indometacin 3157
                                                    acemetacin 1
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