Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:tolazoline
go back to main search page
Accession:CHEBI:28502 term browser browse the term
Definition:A member of the class of imidazoles that is 4,5-dihydro-1H-imidazole substituted by a benzyl group.
Synonyms:exact_synonym: 2-benzyl-4,5-dihydro-1H-imidazole
 related_synonym: 2-Benzyl-2-imidazoline;   2-Benzyl-4,5-imidazoline;   2-Benzylimidazoline;   4,5-Dihydro-2-(phenylmethyl)-1H-imidazole;   Formula=C10H12N2;   InChI=1S/C10H12N2/c1-2-4-9(5-3-1)8-10-11-6-7-12-10/h1-5H,6-8H2,(H,11,12);   InChIKey=JIVZKJJQOZQXQB-UHFFFAOYSA-N;   SMILES=C1CN=C(Cc2ccccc2)N1
 alt_id: CHEBI:27018;   CHEBI:9614
 xref: Beilstein:128757;   CAS:59-98-3;   DrugBank:DB00797;   Drug_Central:2695;   HMDB:HMDB0014935;   KEGG:C07147;   KEGG:D08614;   LINCS:LSM-3020
 xref_mesh: MESH:D014043
 xref: PMID:14366198;   PMID:23321455;   PMID:23438114;   Reaxys:128757;   Wikipedia:Tolazoline



show annotations for term's descendants           Sort by:
tolazoline term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO [Tolazoline co-treated with Glucose] binds to PPARA protein; Tolazoline inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]] CTD PMID:18812576 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Tolazoline inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19918
    role 19894
      application 19729
        pharmaceutical 19565
          drug 19565
            cardiovascular drug 8621
              antihypertensive agent 1940
                tolazoline 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19918
    subatomic particle 19916
      composite particle 19916
        hadron 19916
          baryon 19916
            nucleon 19916
              atomic nucleus 19916
                atom 19916
                  main group element atom 19866
                    p-block element atom 19866
                      carbon group element atom 19811
                        carbon atom 19806
                          organic molecular entity 19806
                            organic molecule 19758
                              organic cyclic compound 19565
                                organic heterocyclic compound 18906
                                  heteroarene 17172
                                    monocyclic heteroarene 14893
                                      azole 14396
                                        diazole 10488
                                          imidazoles 9889
                                            tolazoline 2
paths to the root