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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:tolazoline
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Accession:CHEBI:28502 term browser browse the term
Definition:A member of the class of imidazoles that is 4,5-dihydro-1H-imidazole substituted by a benzyl group.
Synonyms:exact_synonym: 2-benzyl-4,5-dihydro-1H-imidazole
 related_synonym: 2-Benzyl-2-imidazoline;   2-Benzyl-4,5-imidazoline;   2-Benzylimidazoline;   4,5-Dihydro-2-(phenylmethyl)-1H-imidazole;   Formula=C10H12N2;   InChI=1S/C10H12N2/c1-2-4-9(5-3-1)8-10-11-6-7-12-10/h1-5H,6-8H2,(H,11,12);   InChIKey=JIVZKJJQOZQXQB-UHFFFAOYSA-N;   SMILES=C1CN=C(Cc2ccccc2)N1
 alt_id: CHEBI:27018;   CHEBI:9614
 xref: Beilstein:128757;   CAS:59-98-3;   DrugBank:DB00797;   Drug_Central:2695;   HMDB:HMDB0014935;   KEGG:C07147;   KEGG:D08614;   LINCS:LSM-3020
 xref_mesh: MESH:D014043
 xref: PMID:14366198;   PMID:23321455;   PMID:23438114;   Reaxys:128757;   Wikipedia:Tolazoline


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tolazoline term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO [Tolazoline co-treated with Glucose] binds to PPARA protein; Tolazoline inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]] CTD PMID:18812576 NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752
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G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Tolazoline inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,318,025...48,360,219
Ensembl chr 1:48,317,995...48,360,261
JBrowse link

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  CHEBI ontology 19841
    role 19792
      application 19465
        pharmaceutical 19338
          drug 19338
            cardiovascular drug 7657
              antihypertensive agent 1830
                tolazoline 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19841
    subatomic particle 19839
      composite particle 19839
        hadron 19839
          baryon 19839
            nucleon 19839
              atomic nucleus 19839
                atom 19839
                  main group element atom 19732
                    p-block element atom 19732
                      carbon group element atom 19636
                        carbon atom 19625
                          organic molecular entity 19625
                            organic molecule 19556
                              organic cyclic compound 19365
                                organic heterocyclic compound 18486
                                  heteroarene 16537
                                    monocyclic heteroarene 13321
                                      azole 12489
                                        diazole 8147
                                          imidazoles 7668
                                            tolazoline 2
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