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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:tolazoline
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Accession:CHEBI:28502 term browser browse the term
Definition:A member of the class of imidazoles that is 4,5-dihydro-1H-imidazole substituted by a benzyl group.
Synonyms:exact_synonym: 2-benzyl-4,5-dihydro-1H-imidazole
 related_synonym: 2-Benzyl-2-imidazoline;   2-Benzyl-4,5-imidazoline;   2-Benzylimidazoline;   4,5-Dihydro-2-(phenylmethyl)-1H-imidazole;   Formula=C10H12N2;   InChI=1S/C10H12N2/c1-2-4-9(5-3-1)8-10-11-6-7-12-10/h1-5H,6-8H2,(H,11,12);   InChIKey=JIVZKJJQOZQXQB-UHFFFAOYSA-N;   SMILES=C1CN=C(Cc2ccccc2)N1
 alt_id: CHEBI:27018;   CHEBI:9614
 xref: Beilstein:128757;   CAS:59-98-3;   DrugBank:DB00797;   Drug_Central:2695;   HMDB:HMDB0014935;   KEGG:C07147;   KEGG:D08614;   LINCS:LSM-3020
 xref_mesh: MESH:D014043
 xref: PMID:14366198;   PMID:23321455;   PMID:23438114;   Reaxys:128757;   Wikipedia:Tolazoline



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tolazoline term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO [Tolazoline co-treated with Glucose] binds to PPARA protein; Tolazoline inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]] CTD PMID:18812576 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
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G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Tolazoline inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268
JBrowse link

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  CHEBI ontology 19659
    role 19634
      application 19465
        pharmaceutical 19355
          drug 19355
            cardiovascular drug 8438
              antihypertensive agent 1882
                tolazoline 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19659
    subatomic particle 19658
      composite particle 19658
        hadron 19658
          baryon 19658
            nucleon 19658
              atomic nucleus 19700
                atom 19658
                  main group element atom 19607
                    p-block element atom 19607
                      carbon group element atom 19550
                        carbon atom 19547
                          organic molecular entity 19588
                            organic molecule 19506
                              organic cyclic compound 19324
                                organic heterocyclic compound 18682
                                  heteroarene 16681
                                    monocyclic heteroarene 14210
                                      azole 13579
                                        diazole 8624
                                          imidazoles 7723
                                            tolazoline 2
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