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ONTOLOGY REPORT - ANNOTATIONS
Term:temozolomide
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Accession:CHEBI:72564 term browser browse the term
Definition:An imidazotetrazine that is 3,4-dihydroimidazo[5,1-d][1,2,3,5]tetrazine which is substituted at positions 3, 4, and 8 by methyl, oxo, and carboxamide groups, respectively. A prodrug for MTIC (5-(3-methyltriaz-1-en-1-yl)-1H-imidazole-4-carboxamide, formed by spontaneous hydrolysis of temozolomide in the body), it is used as an oral alkylating agent for the treatment of newly diagnosed malignant glioblastoma multiforme (concomitantly with radiotherapy) and malignant melanoma.
Synonyms:related_synonym: 3,4-dihydro-3-methyl-4-oxoimidazo(5,1-d)-1,2,3,5-tetrazine-8-carboxamide;   3,4-dihydro-3-methyl-4-oxoimidazo(5,1-d)-as-tetrazine-8-carboxamide;   3-methyl-4-oxo-3,4-dihydroimidazo(5,1-d)(1,2,3,5)tetrazine-8-carboxamide;   8-carbamoyl-3-methylimidazo(5,1-d)-1,2,3,5-tetrazin-4(3H)-one;   BRN 5547136;   CCRG-81045;   CCRIS 8996;   Formula=C6H6N6O2;   InChI=1S/C6H6N6O2/c1-11-6(14)12-2-8-3(4(7)13)5(12)9-10-11/h2H,1H3,(H2,7,13);   InChIKey=BPEGJWRSRHCHSN-UHFFFAOYSA-N;   M&B 39831;   MB 39831;   NSC 362856;   SMILES=Cn1nnc2c(ncn2c1=O)C(N)=O;   Sch 52365;   TMZ;   Temodal;   Temodar;   methazolastone;   temozolomida;   temozolomidum
 xref: CAS:85622-93-1 "ChemIDplus";   DrugBank:DB00853;   Drug_Central:2589 "DrugCentral";   HMDB:HMDB0014991;   KEGG:D06067;   LINCS:LSM-4590
 xref_mesh: MESH:C047246
 xref: PMID:22680781 "Europe PMC";   PMID:22818211 "Europe PMC";   PMID:23246370 "Europe PMC";   PMID:23254891 "Europe PMC";   PMID:23293540 "Europe PMC";   PMID:23335050 "Europe PMC";   PMID:23362460 "Europe PMC";   PMID:23377829 "Europe PMC";   PMID:23385995 "Europe PMC";   PMID:23389760 "Europe PMC";   Patent:DE3231255;   Reaxys:5547136 "Reaxys";   Wikipedia:Temozolomide

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temozolomide term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcc2 ATP binding cassette subfamily C member 2 JBrowse link 1 263,554,426 263,612,556 RGD:6480464
G Abcg5 ATP binding cassette subfamily G member 5 JBrowse link 6 7,935,771 7,961,207 RGD:6480464
G Agr3 anterior gradient 3, protein disulphide isomerase family member JBrowse link 6 55,371,738 55,424,233 RGD:6480464
G Agt angiotensinogen JBrowse link 19 57,321,594 57,333,460 RGD:6480464
G Akr1b1 aldo-keto reductase family 1 member B JBrowse link 4 61,706,866 61,720,959 RGD:6480464
G Akt1 AKT serine/threonine kinase 1 JBrowse link 6 137,218,398 137,239,970 RGD:6480464
G Aldh1a3 aldehyde dehydrogenase 1 family, member A3 JBrowse link 1 127,302,920 127,337,828 RGD:6480464
G Ank2 ankyrin 2 JBrowse link 2 231,224,643 231,522,655 RGD:6480464
G Ankrd1 ankyrin repeat domain 1 JBrowse link 1 254,726,985 254,745,673 RGD:6480464
G Ap1s2 adaptor related protein complex 1 subunit sigma 2 JBrowse link X 32,329,883 32,376,301 RGD:6480464
G Apc APC regulator of WNT signaling pathway JBrowse link 18 27,011,710 27,106,323 RGD:6480464
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 JBrowse link 15 27,849,943 27,852,083 RGD:6480464
G Arf1 ADP-ribosylation factor 1 JBrowse link 10 45,562,700 45,579,214 RGD:6480464
G Arrdc2 arrestin domain containing 2 JBrowse link 16 20,352,480 20,356,612 RGD:6480464
G Atm ATM serine/threonine kinase JBrowse link 8 58,015,938 58,119,973 RGD:6480464
G Atr ATR serine/threonine kinase JBrowse link 8 103,673,578 103,770,886 RGD:6480464
G B4galnt2 beta-1,4-N-acetyl-galactosaminyl transferase 2 JBrowse link 10 83,677,768 83,701,487 RGD:6480464
G Bax BCL2 associated X, apoptosis regulator JBrowse link 1 101,451,801 101,457,207 RGD:6480464
G Bcl2 BCL2, apoptosis regulator JBrowse link 13 26,605,426 26,769,374 RGD:6480464
G Bcl2l1 Bcl2-like 1 JBrowse link 3 148,259,594 148,314,191 RGD:6480464
G Bcl2l11 BCL2 like 11 JBrowse link 3 120,726,906 120,764,192 RGD:6480464
G Becn1 beclin 1 JBrowse link 10 89,209,944 89,225,297 RGD:6480464
G Birc5 baculoviral IAP repeat-containing 5 JBrowse link 10 106,856,097 106,864,419 RGD:6480464
G Bmp5 bone morphogenetic protein 5 JBrowse link 8 82,669,466 82,950,273 RGD:6480464
G Brca2 BRCA2, DNA repair associated JBrowse link 12 503,660 544,754 RGD:6480464
G Cadm1 cell adhesion molecule 1 JBrowse link 8 51,858,906 52,200,591 RGD:6480464
G Casp12 caspase 12 JBrowse link 8 2,658,892 2,686,160 RGD:6480464
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:6480464
G Casp7 caspase 7 JBrowse link 1 277,190,557 277,242,779 RGD:6480464
G Casp8 caspase 8 JBrowse link 9 65,614,142 65,662,624 RGD:6480464
G Casp9 caspase 9 JBrowse link 5 160,356,211 160,373,774 RGD:6480464
G Ccl2 C-C motif chemokine ligand 2 JBrowse link 10 69,412,065 69,413,863 RGD:6480464
G Ccn4 cellular communication network factor 4 JBrowse link 7 107,695,227 107,723,759 RGD:6480464
G Ccnb1 cyclin B1 JBrowse link 2 30,782,133 30,791,106 RGD:6480464
G Ccnd1 cyclin D1 JBrowse link 1 218,090,750 218,100,447 RGD:6480464
G Cd44 CD44 molecule (Indian blood group) JBrowse link 3 92,695,083 92,783,820 RGD:6480464
G Cd59 CD59 molecule JBrowse link 3 94,010,481 94,028,660 RGD:6480464
G Cdc25c cell division cycle 25C JBrowse link 18 27,528,768 27,550,316 RGD:6480464
G Cdh13 cadherin 13 JBrowse link 19 50,848,793 51,971,618 RGD:6480464
G Cdk1 cyclin-dependent kinase 1 JBrowse link 20 20,576,341 20,591,510 RGD:6480464
G Cdkn1a cyclin-dependent kinase inhibitor 1A JBrowse link 20 6,348,422 6,358,864 RGD:6480464
G Cdkn1b cyclin-dependent kinase inhibitor 1B JBrowse link 4 168,689,043 168,694,159 RGD:6480464
G Cdkn1c cyclin-dependent kinase inhibitor 1C JBrowse link 1 216,661,067 216,663,791 RGD:6480464
G Chd2 chromodomain helicase DNA binding protein 2 JBrowse link 1 134,757,934 134,873,053 RGD:6480464
G Chek1 checkpoint kinase 1 JBrowse link 8 39,181,162 39,201,588 RGD:6480464
G Chek2 checkpoint kinase 2 JBrowse link 12 51,845,574 51,878,098 RGD:6480464
G Col1a1 collagen type I alpha 1 chain JBrowse link 10 82,745,801 82,762,790 RGD:6480464
G Cox4i1 cytochrome c oxidase subunit 4i1 JBrowse link 19 54,245,958 54,252,198 RGD:6480464
G Cox4i2 cytochrome c oxidase subunit 4i2 JBrowse link 3 148,234,546 148,245,424 RGD:6480464
G Csf2 colony stimulating factor 2 JBrowse link 10 39,602,089 39,604,070 RGD:6480464
G Csgalnact1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 JBrowse link 16 22,704,318 23,075,071 RGD:6480464
G Csrp3 cysteine and glycine rich protein 3 JBrowse link 1 104,147,205 104,166,389 RGD:6480464
G Cxcl1 C-X-C motif chemokine ligand 1 JBrowse link 14 18,743,678 18,745,457 RGD:6480464
G Cxcl2 C-X-C motif chemokine ligand 2 JBrowse link 14 18,731,346 18,733,391 RGD:6480464
G Cxcl3 chemokine (C-X-C motif) ligand 3 JBrowse link 14 18,820,168 18,839,659 RGD:6480464
G Dct dopachrome tautomerase JBrowse link 15 103,208,174 103,245,033 RGD:6480464
G Def6 DEF6 guanine nucleotide exchange factor JBrowse link 20 7,788,120 7,809,011 RGD:6480464
G Dhrs3 dehydrogenase/reductase 3 JBrowse link 5 162,809,090 162,843,385 RGD:6480464
G Dhx37 DEAH-box helicase 37 JBrowse link 12 36,594,058 36,614,165 RGD:6480464
G Dmrtc2 DMRT-like family C2 JBrowse link 1 81,734,256 81,741,419 RGD:6480464
G Dyrk1b dual specificity tyrosine phosphorylation regulated kinase 1B JBrowse link 1 85,112,819 85,120,840 RGD:6480464
G Ednra endothelin receptor type A JBrowse link 19 33,928,356 33,991,703 RGD:6480464
G Eif4a2 eukaryotic translation initiation factor 4A2 JBrowse link 11 81,373,047 81,379,680 RGD:6480464
G Elmo1 engulfment and cell motility 1 JBrowse link 17 46,352,102 46,888,788 RGD:6480464
G Etv1 ETS variant transcription factor 1 JBrowse link 6 58,467,215 58,558,640 RGD:6480464
G Extl1 exostosin-like glycosyltransferase 1 JBrowse link 5 152,573,755 152,588,956 RGD:6480464
G Fancc FA complementation group C JBrowse link 17 826,512 955,703 RGD:6480464
G Fancd2 FA complementation group D2 JBrowse link 4 145,489,869 145,551,479 RGD:6480464
G Faslg Fas ligand JBrowse link 13 79,696,811 79,717,581 RGD:6480464
G Fbxo32 F-box protein 32 JBrowse link 7 98,065,664 98,098,071 RGD:6480464
G Fgf2 fibroblast growth factor 2 JBrowse link 2 124,081,072 124,134,133 RGD:6480464
G Fhl2 four and a half LIM domains 2 JBrowse link 9 49,920,611 49,994,906 RGD:6480464
G Foxf2 forkhead box F2 JBrowse link 17 34,150,417 34,156,450 RGD:6480464
G Fut8 fucosyltransferase 8 JBrowse link 6 100,305,957 100,537,208 RGD:6480464
G Gabra2 gamma-aminobutyric acid type A receptor alpha2 subunit JBrowse link 14 39,662,411 39,801,082 RGD:6480464
G Galnt15 polypeptide N-acetylgalactosaminyltransferase 15 JBrowse link 16 8,127,599 8,178,101 RGD:6480464
G Garnl3 GTPase activating Rap/RanGAP domain-like 3 JBrowse link 3 12,034,131 12,176,591 RGD:6480464
G Gfap glial fibrillary acidic protein JBrowse link 10 90,990,762 90,999,435 RGD:6480464
G Glrb glycine receptor, beta JBrowse link 2 179,768,040 179,842,612 RGD:6480464
G H2ax H2A.X variant histone JBrowse link 8 48,665,652 48,666,981 RGD:6480464
G Hhat hedgehog acyltransferase JBrowse link 13 111,235,325 111,489,075 RGD:6480464
G Hprt1 hypoxanthine phosphoribosyltransferase 1 JBrowse link X 158,196,640 158,228,815 RGD:6480464
G Hspa1a heat shock protein family A (Hsp70) member 1A JBrowse link 20 4,875,834 4,881,751 RGD:6480464
G Hspb1 heat shock protein family B (small) member 1 JBrowse link 12 23,839,390 23,841,051 RGD:6480464
G Igf2 insulin-like growth factor 2 JBrowse link 1 215,828,102 215,839,081 RGD:6480464
G Il1r1 interleukin 1 receptor type 1 JBrowse link 9 46,962,291 47,038,139 RGD:6480464
G Il24 interleukin 24 JBrowse link 13 47,618,451 47,623,849 RGD:6480464
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:6480464
G Inhba inhibin subunit beta A JBrowse link 17 51,894,869 51,919,998 RGD:6480464
G Ipo4 importin 4 JBrowse link 15 34,304,425 34,314,552 RGD:6480464
G Kcnab2 potassium voltage-gated channel subfamily A regulatory beta subunit 2 JBrowse link 5 169,570,327 169,658,875 RGD:6480464
G Krt8 keratin 8 JBrowse link 7 143,596,511 143,603,745 RGD:6480464
G Lbp lipopolysaccharide binding protein JBrowse link 3 154,786,232 154,812,910 RGD:6480464
G Lif LIF, interleukin 6 family cytokine JBrowse link 14 84,482,652 84,500,574 RGD:6480464
G Lins1 lines homolog 1 JBrowse link 1 127,599,647 127,625,583 RGD:6480464
G Lman1l lectin, mannose-binding, 1 like JBrowse link 8 62,386,806 62,400,370 RGD:6480464
G Lmtk2 lemur tyrosine kinase 2 JBrowse link 12 12,409,876 12,546,111 RGD:6480464
G Map1lc3b microtubule-associated protein 1 light chain 3 beta JBrowse link 19 53,635,449 53,643,970 RGD:6480464
G Masp1 mannan-binding lectin serine peptidase 1 JBrowse link 11 80,736,424 80,806,278 RGD:6480464
G Mecom MDS1 and EVI1 complex locus JBrowse link 2 117,396,084 117,993,604 RGD:6480464
G Mgmt O-6-methylguanine-DNA methyltransferase JBrowse link 1 209,237,255 209,464,189 RGD:6480464
G Mgst2 microsomal glutathione S-transferase 2 JBrowse link 2 140,708,396 140,727,381 RGD:6480464
G Mlh1 mutL homolog 1 JBrowse link 8 119,486,655 119,523,716 RGD:6480464
G Mlph melanophilin JBrowse link 9 98,072,965 98,108,429 RGD:6480464
G Mmp9 matrix metallopeptidase 9 JBrowse link 3 161,413,410 161,421,473 RGD:6480464
G Mpg N-methylpurine-DNA glycosylase JBrowse link 10 15,661,768 15,667,995 RGD:6480464
G Mpst mercaptopyruvate sulfurtransferase JBrowse link 7 119,626,636 119,631,317 RGD:6480464
G Msh2 mutS homolog 2 JBrowse link 6 11,215,951 11,274,916 RGD:6480464
G Mt2A metallothionein 2A JBrowse link 19 11,307,966 11,308,740 RGD:6480464
G Mtor mechanistic target of rapamycin kinase JBrowse link 5 165,263,813 165,373,967 RGD:6480464
G Mturn maturin, neural progenitor differentiation regulator homolog JBrowse link 4 84,854,341 84,875,300 RGD:6480464
G Nbl1 NBL1, DAN family BMP antagonist JBrowse link 5 157,524,569 157,535,701 RGD:6480464
G Nfat5 nuclear factor of activated T-cells 5 JBrowse link 19 38,446,059 38,533,735 RGD:6480464
G Nfib nuclear factor I/B JBrowse link 5 100,436,343 100,647,962 RGD:6480464
G Nfix nuclear factor I X JBrowse link 19 25,818,640 25,914,777 RGD:6480464
G Nfkbia NFKB inhibitor alpha JBrowse link 6 76,267,227 76,270,457 RGD:6480464
G Nin ninein JBrowse link 6 92,423,412 92,527,776 RGD:6480464
G Nkd2 NKD inhibitor of WNT signaling pathway 2 JBrowse link 1 32,054,390 32,085,416 RGD:6480464
G Npas2 neuronal PAS domain protein 2 JBrowse link 9 45,901,262 46,081,880 RGD:6480464
G Npl N-acetylneuraminate pyruvate lyase JBrowse link 13 70,938,073 70,981,179 RGD:6480464
G Nr2f1 nuclear receptor subfamily 2, group F, member 1 JBrowse link 2 5,569,954 5,579,894 RGD:6480464
G P3h3 prolyl 3-hydroxylase 3 JBrowse link 4 157,359,331 157,375,186 RGD:6480464
G Parp1 poly (ADP-ribose) polymerase 1 JBrowse link 13 98,857,255 98,889,444 RGD:6480464
G Pcdhb2 protocadherin beta 2 JBrowse link 18 30,375,798 30,378,194 RGD:6480464
G Pde5a phosphodiesterase 5A JBrowse link 2 226,899,604 227,044,916 RGD:6480464
G Pgm2 phosphoglucomutase 2 JBrowse link 14 45,829,440 45,863,883 RGD:6480464
G Phc2 polyhomeotic homolog 2 JBrowse link 5 146,832,552 146,931,444 RGD:6480464
G Phlda1 pleckstrin homology-like domain, family A, member 1 JBrowse link 7 54,247,460 54,249,664 RGD:6480464
G Piga phosphatidylinositol glycan anchor biosynthesis, class A JBrowse link X 31,786,823 31,799,751 RGD:6480464
G Pik3c3 phosphatidylinositol 3-kinase, catalytic subunit type 3 JBrowse link 18 22,964,121 23,047,896 RGD:6480464
G Pik3cd phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta JBrowse link 5 166,602,053 166,628,028 RGD:6480464
G Pitpnc1 phosphatidylinositol transfer protein, cytoplasmic 1 JBrowse link 10 95,429,879 95,697,734 RGD:6480464
G Pkp3 plakophilin 3 JBrowse link 1 213,884,795 213,897,783 RGD:6480464
G Plekhg5 pleckstrin homology and RhoGEF domain containing G5 JBrowse link 5 169,244,778 169,288,310 RGD:6480464
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 JBrowse link 18 62,159,128 62,179,635 RGD:6480464
G Pms1 PMS1 homolog 1, mismatch repair system component JBrowse link 9 53,120,656 53,206,520 RGD:6480464
G Pms2 PMS1 homolog 2, mismatch repair system component JBrowse link 12 12,714,394 12,738,654 RGD:6480464
G Polb DNA polymerase beta JBrowse link 16 74,237,001 74,260,272 RGD:6480464
G Polg2 DNA polymerase gamma 2, accessory subunit JBrowse link 10 94,968,836 94,979,259 RGD:6480464
G Popdc3 popeye domain containing 3 JBrowse link 20 50,394,617 50,422,551 RGD:6480464
G Prex1 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 JBrowse link 3 163,329,580 163,477,822 RGD:6480464
G Prkaa2 protein kinase AMP-activated catalytic subunit alpha 2 JBrowse link 5 124,568,845 124,642,569 RGD:6480464
G Prl prolactin JBrowse link 17 39,814,236 39,824,299 RGD:6480464
G Prrx2 paired related homeobox 2 JBrowse link 3 9,681,871 9,718,051 RGD:6480464
G Prss12 serine protease 12 JBrowse link 2 227,657,983 227,717,884 RGD:6480464
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:6480464
G Qpct glutaminyl-peptide cyclotransferase JBrowse link 6 1,657,110 1,689,575 RGD:6480464
G Rab27b RAB27B, member RAS oncogene family JBrowse link 18 68,486,006 68,644,595 RGD:6480464
G Rb1 RB transcriptional corepressor 1 JBrowse link 15 55,081,582 55,209,060 RGD:6480464
G Rbm19 RNA binding motif protein 19 JBrowse link 12 41,907,978 41,993,969 RGD:6480464
G Rela RELA proto-oncogene, NF-kB subunit JBrowse link 1 220,992,770 221,003,249 RGD:6480464
G Rgcc regulator of cell cycle JBrowse link 15 61,551,861 61,564,695 RGD:6480464
G Rgp1 RGP1 homolog, RAB6A GEF complex partner 1 JBrowse link 5 59,080,290 59,088,777 RGD:6480464
G Rhobtb3 Rho-related BTB domain containing 3 JBrowse link 2 2,627,655 2,683,305 RGD:6480464
G Sat1 spermidine/spermine N1-acetyl transferase 1 JBrowse link X 43,626,480 43,629,767 RGD:6480464
G Scamp5 secretory carrier membrane protein 5 JBrowse link 8 62,221,820 62,266,269 RGD:6480464
G Scn8a sodium voltage-gated channel alpha subunit 8 JBrowse link 7 142,575,629 142,683,659 RGD:6480464
G Sdc1 syndecan 1 JBrowse link 6 33,885,576 33,908,038 RGD:6480464
G Sema3a semaphorin 3A JBrowse link 4 18,170,375 18,545,190 RGD:6480464
G Serpinb1a serpin family B member 1A JBrowse link 17 32,903,089 32,911,498 RGD:6480464
G Sf1 splicing factor 1 JBrowse link 1 221,735,512 221,749,216 RGD:6480464
G Slc14a1 solute carrier family 14 member 1 (Kidd blood group) JBrowse link 18 74,461,064 74,504,475 RGD:6480464
G Slc15a2 solute carrier family 15 member 2 JBrowse link 11 66,932,664 66,961,708 RGD:6480464
G Slc22a5 solute carrier family 22 member 5 JBrowse link 10 39,201,101 39,228,090 RGD:6480464
G Slpi secretory leukocyte peptidase inhibitor JBrowse link 3 160,799,979 160,802,228 RGD:6480464
G Sod2 superoxide dismutase 2 JBrowse link 1 47,914,757 47,921,587 RGD:6480464
G Sox9 SRY-box transcription factor 9 JBrowse link 10 101,288,528 101,294,030 RGD:6480464
G Sparc secreted protein acidic and cysteine rich JBrowse link 10 40,742,390 40,764,232 RGD:6480464
G Spen spen family transcriptional repressor JBrowse link 5 160,015,573 160,070,915 RGD:6480464
G Sqle squalene epoxidase JBrowse link 7 99,609,929 99,624,803 RGD:6480464
G St3gal1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 JBrowse link 7 107,895,045 107,963,158 RGD:6480464
G Stc1 stanniocalcin 1 JBrowse link 15 50,891,137 50,901,791 RGD:6480464
G Stxbp6 syntaxin binding protein 6 JBrowse link 6 65,086,483 65,319,527 RGD:6480464
G Synpo2 synaptopodin 2 JBrowse link 2 227,255,243 227,411,924 RGD:6480464
G Tagln transgelin JBrowse link 8 50,222,895 50,228,369 RGD:6480464
G Tbx3 T-box transcription factor 3 JBrowse link 12 42,479,518 42,494,588 RGD:6480464
G Tcim transcriptional and immune response regulator JBrowse link 16 72,401,526 72,403,180 RGD:6480464
G Tdrp testis development related protein JBrowse link 16 80,729,342 80,755,397 RGD:6480464
G Tert telomerase reverse transcriptase JBrowse link 1 32,250,876 32,275,330 RGD:6480464
G Tfap2c transcription factor AP-2 gamma JBrowse link 3 170,550,314 170,558,197 RGD:6480464
G Tfdp1 transcription factor Dp-1 JBrowse link 16 81,088,642 81,127,244 RGD:6480464
G Tfpi2 tissue factor pathway inhibitor 2 JBrowse link 4 28,947,951 28,953,261 RGD:6480464
G Thbd thrombomodulin JBrowse link 3 142,748,673 142,752,325 RGD:6480464
G Tmem158 transmembrane protein 158 JBrowse link 8 132,344,710 132,345,708 RGD:6480464
G Tmem19 transmembrane protein 19 JBrowse link 7 58,316,583 58,343,761 RGD:6480464
G Tmprss15 transmembrane serine protease 15 JBrowse link 11 17,561,591 17,684,903 RGD:6480464
G Tnc tenascin C JBrowse link 5 79,789,686 79,874,555 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6480464
G Tnfaip3 TNF alpha induced protein 3 JBrowse link 1 14,401,103 14,416,369 RGD:6480464
G Tnfrsf19 TNF receptor superfamily member 19 JBrowse link 15 41,249,820 41,316,203 RGD:6480464
G Tnfsf10 TNF superfamily member 10 JBrowse link 2 113,008,008 113,026,899 RGD:6480464
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:6480464
G Tpd52l1 TPD52 like 1 JBrowse link 1 28,454,949 28,578,736 RGD:6480464
G Trim50 tripartite motif-containing 50 JBrowse link 12 24,348,426 24,365,467 RGD:6480464
G Tsc1 TSC complex subunit 1 JBrowse link 3 7,219,955 7,269,063 RGD:6480464
G Tufm Tu translation elongation factor, mitochondrial JBrowse link 1 197,903,582 197,907,189 RGD:6480464
G Tulp3 TUB like protein 3 JBrowse link 4 161,636,084 161,677,807 RGD:6480464
G Vamp4 vesicle-associated membrane protein 4 JBrowse link 13 80,460,699 80,483,597 RGD:6480464
G Vat1l vesicle amine transport 1-like JBrowse link 19 46,525,895 46,693,838 RGD:6480464
G Vegfa vascular endothelial growth factor A JBrowse link 9 17,340,341 17,355,681 RGD:6480464
G Vldlr very low density lipoprotein receptor JBrowse link 1 245,236,819 245,273,688 RGD:6480464
G Wasf2 WASP family member 2 JBrowse link 5 151,319,382 151,385,051 RGD:6480464
G Wee1 WEE1 G2 checkpoint kinase JBrowse link 1 174,765,228 174,790,882 RGD:6480464
G Wfdc1 WAP four-disulfide core domain 1 JBrowse link 19 52,313,771 52,332,721 RGD:6480464
G Wnt5a Wnt family member 5A JBrowse link 16 4,469,451 4,490,271 RGD:6480464
G Xaf1 XIAP associated factor 1 JBrowse link 10 58,860,647 58,872,782 RGD:6480464
G Xiap X-linked inhibitor of apoptosis JBrowse link X 128,409,425 128,455,786 RGD:6480464
G Zbtb7a zinc finger and BTB domain containing 7a JBrowse link 7 11,429,266 11,446,119 RGD:6480464
G Zc3h13 zinc finger CCCH type containing 13 JBrowse link 15 57,340,522 57,405,287 RGD:6480464
G Zfp112 zinc finger protein 112 JBrowse link 1 80,944,118 80,959,072 RGD:6480464
G Zfp655 zinc finger protein 655 JBrowse link 12 11,122,779 11,146,182 RGD:6480464
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19669
    role 19613
      application 19235
        pro-agent 8765
          prodrug 8562
            temozolomide 210
Path 2
Term Annotations click to browse term
  CHEBI ontology 19669
    subatomic particle 19665
      composite particle 19665
        hadron 19665
          baryon 19665
            nucleon 19665
              atomic nucleus 19665
                atom 19665
                  main group element atom 19545
                    p-block element atom 19545
                      carbon group element atom 19428
                        carbon atom 19420
                          organic molecular entity 19420
                            organic group 18343
                              organic divalent group 18334
                                organodiyl group 18334
                                  carbonyl group 18222
                                    carbonyl compound 18222
                                      carboxylic acid 17923
                                        carboacyl group 16943
                                          univalent carboacyl group 16943
                                            carbamoyl group 16622
                                              carboxamide 16622
                                                monocarboxylic acid amide 13180
                                                  temozolomide 210
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.