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ONTOLOGY REPORT - ANNOTATIONS


Term:bambuterol
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Accession:CHEBI:553827 term browser browse the term
Definition:A carbamate ester that is terbutaline in which both of the phenolic hydroxy groups have been protected as the corresponding N,N-dimethylcarbamates. A long acting beta-adrenoceptor agonist used in the treatment of asthma, it is a prodrug for terbutaline.
Synonyms:exact_synonym: 5-[2-(tert-butylamino)-1-hydroxyethyl]benzene-1,3-diyl bis(dimethylcarbamate)
 related_synonym: (+-)-5-(2-(tert-butylamino)-1-hydroxyethyl)-m-phenylene bis(dimethylcarbamate);   Formula=C18H29N3O5;   InChI=1S/C18H29N3O5/c1-18(2,3)19-11-15(22)12-8-13(25-16(23)20(4)5)10-14(9-12)26-17(24)21(6)7/h8-10,15,19,22H,11H2,1-7H3;   InChIKey=ANZXOIAKUNOVQU-UHFFFAOYSA-N;   SMILES=CN(C)C(=O)Oc1cc(OC(=O)N(C)C)cc(c1)C(O)CNC(C)(C)C;   bambuterolum;   terbutaline bis(dimethylcarbamate);   terbutaline bisdimethylcarbamate
 xref: Beilstein:8158052 "Beilstein";   CAS:81732-65-2 "ChemIDplus";   CAS:81732-65-2 "KEGG DRUG";   DrugBank:DB01408;   Drug_Central:285 "DrugCentral";   KEGG:D07377;   LINCS:LSM-4346
 xref_mesh: MESH:C047766
 xref: PMID:18582854 "Europe PMC";   Patent:EP43807;   Patent:US4419364;   Reaxys:8158052 "Reaxys"


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bambuterol term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ache acetylcholinesterase JBrowse link 12 22,472,358 22,477,052 RGD:6480464
G Bche butyrylcholinesterase JBrowse link 2 171,104,476 171,196,186 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19679
    role 19623
      application 19246
        anti-asthmatic agent 9174
          anti-asthmatic drug 8545
            bambuterol 2
              (R)-bambuterol 0
              (S)-bambuterol 0
              bambuterol hydrochloride + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19679
    subatomic particle 19675
      composite particle 19675
        hadron 19675
          baryon 19675
            nucleon 19675
              atomic nucleus 19675
                atom 19675
                  main group element atom 19555
                    main group molecular entity 19555
                      s-block molecular entity 19336
                        hydrogen molecular entity 19325
                          hydrides 18249
                            inorganic hydride 17113
                              pnictogen hydride 17071
                                nitrogen hydride 16891
                                  azane 16568
                                    ammonia 16565
                                      organic amino compound 16564
                                        amino alcohol 862
                                          ethanolamines 754
                                            phenylethanolamines 575
                                              terbutaline 52
                                                bambuterol 2
                                                  (R)-bambuterol 0
                                                  (S)-bambuterol 0
                                                  bambuterol hydrochloride + 0
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