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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:sulindac
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Accession:CHEBI:9352 term browser browse the term
Definition:A monocarboxylic acid that is 1-benzylidene-1H-indene which is substituted at positions 2, 3, and 5 by methyl, carboxymethyl, and fluorine respectively, and in which the phenyl group of the benzylidene moiety is substituted at the para position by a methylsulfinyl group. It is a prodrug for the corresponding sulfide, a non-steroidal anti-inflammatory drug, used particularly in the treatment of acute and chronic inflammatory conditions.
Synonyms:exact_synonym: {(1Z)-5-fluoro-2-methyl-1-[4-(methylsulfinyl)benzylidene]-1H-inden-3-yl}acetic acid
 related_synonym: (Z)-5-Fluoro-2-methyl-1-((p-(methylsulfinyl)phenyl)methylene)-1H-indene-3-acetic acid;   Clinoril;   Formula=C20H17FO3S;   InChI=1S/C20H17FO3S/c1-12-17(9-13-3-6-15(7-4-13)25(2)24)16-8-5-14(21)10-19(16)18(12)11-20(22)23/h3-10H,11H2,1-2H3,(H,22,23)/b17-9-;   InChIKey=MLKXDPUZXIRXEP-MFOYZWKCSA-N;   SMILES=CC1=C(CC(O)=O)c2cc(F)ccc2C\\1=C/c1ccc(cc1)S(C)=O;   Sulindacum;   cis-5-Fluoro-2-methyl-1-((4-(methylsulfinyl)phenyl)methylene)-1H-indene-3-acetic acid;   cis-5-Fluoro-2-methyl-1-((p-methylsulfinyl)benzylidene)indene-3-acetic acid;   sulindaco
 xref: Beilstein:2951842;   CAS:38194-50-2;   DrugBank:DB00605;   Drug_Central:2534;   HMDB:HMDB0014743;   KEGG:C01531;   KEGG:D00120
 xref_mesh: MESH:D013467
 xref: PDBeChem:SUZ;   PMID:11569947;   PMID:11927004;   PMID:12406542;   PMID:15020200;   PMID:15123337;   PMID:19884509;   PMID:23689354;   PMID:23804703;   Patent:DE2039426;   Patent:US3654349;   Reaxys:2951842;   Wikipedia:Sulindac


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sulindac term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc1 ATP binding cassette subfamily C member 1 increases expression
multiple interactions
ISO Sulindac results in increased expression of ABCC1 protein
Acetylcysteine inhibits the reaction [Sulindac results in increased expression of ABCC1 protein]
CTD PMID:11820781 NCBI chr10:549,537...672,235
Ensembl chr10:549,883...672,196
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 multiple interactions
increases expression
ISO Acetylcysteine inhibits the reaction [Sulindac results in increased expression of ABCC3 protein] CTD PMID:11820781 NCBI chr10:82,047,308...82,116,928
Ensembl chr10:82,047,863...82,117,109
JBrowse link
G Abcd3 ATP binding cassette subfamily D member 3 increases expression EXP Sulindac results in increased expression of ABCD3 mRNA CTD PMID:24136188 NCBI chr 2:225,335,708...225,389,120
Ensembl chr 2:225,335,718...225,389,120
JBrowse link
G Abhd16a abhydrolase domain containing 16A, phospholipase increases expression EXP Sulindac results in increased expression of ABHD16A mRNA CTD PMID:24136188 NCBI chr20:5,080,070...5,094,935
Ensembl chr20:5,080,070...5,094,935
JBrowse link
G Abi1 abl-interactor 1 decreases expression EXP Sulindac results in decreased expression of ABI1 mRNA CTD PMID:24136188 NCBI chr17:89,951,662...90,033,334
Ensembl chr17:89,951,752...90,033,328
JBrowse link
G Acad9 acyl-CoA dehydrogenase family, member 9 multiple interactions EXP [Sulindac co-treated with lipopolysaccharide, E coli O55-B5] affects the expression of ACAD9 mRNA CTD PMID:20371263 NCBI chr 2:122,782,051...122,806,166
Ensembl chr 2:122,782,060...122,805,768
JBrowse link
G Acp2 acid phosphatase 2, lysosomal increases expression ISO Sulindac results in increased expression of ACP2 mRNA CTD PMID:11906190 NCBI chr 3:80,020,346...80,030,365
Ensembl chr 3:80,021,440...80,030,363
JBrowse link
G Acsl1 acyl-CoA synthetase long-chain family member 1 multiple interactions EXP [Sulindac co-treated with lipopolysaccharide, E coli O55-B5] affects the expression of ACSL1 mRNA CTD PMID:20371263 NCBI chr16:48,937,456...49,003,898
Ensembl chr16:48,937,456...49,003,246
JBrowse link
G Actr10 actin related protein 10 decreases expression EXP Sulindac results in decreased expression of ACTR10 mRNA CTD PMID:24136188 NCBI chr 6:93,385,457...93,411,605
Ensembl chr 6:93,385,457...93,411,576
JBrowse link
G Acy1 aminoacylase 1 increases expression EXP Sulindac results in increased expression of ACY1 mRNA CTD PMID:24136188 NCBI chr 8:115,134,792...115,140,171
Ensembl chr 8:115,134,765...115,140,080
JBrowse link
G Add1 adducin 1 increases expression EXP Sulindac results in increased expression of ADD1 mRNA CTD PMID:24136188 NCBI chr14:81,367,466...81,426,610
Ensembl chr14:81,367,468...81,426,496
JBrowse link
G Adhfe1 alcohol dehydrogenase, iron containing, 1 multiple interactions EXP [Sulindac co-treated with lipopolysaccharide, E coli O55-B5] affects the expression of ADHFE1 mRNA CTD PMID:20371263 NCBI chr 5:9,403,194...9,429,783
Ensembl chr 5:9,403,196...9,429,859
JBrowse link
G Adipor2 adiponectin receptor 2 multiple interactions EXP [Sulindac co-treated with lipopolysaccharide, E coli O55-B5] affects the expression of ADIPOR2 mRNA CTD PMID:20371263 NCBI chr 4:151,412,135...151,480,108
Ensembl chr 4:151,414,684...151,428,894
JBrowse link
G Adss adenylosuccinate synthase increases expression EXP Sulindac results in increased expression of ADSS mRNA CTD PMID:24136188 NCBI chr13:95,913,426...95,943,761
Ensembl chr13:95,913,426...95,943,761
JBrowse link
G Ahr aryl hydrocarbon receptor increases localization
multiple interactions
ISO
EXP
Sulindac results in increased localization of AHR protein
Sulindac binds to and results in increased activity of AHR protein
CTD PMID:16531450, PMID:17985343 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Aif1l allograft inflammatory factor 1-like decreases expression ISO Sulindac results in decreased expression of AIF1L mRNA CTD PMID:11906190 NCBI chr 3:9,237,944...9,262,628
Ensembl chr 3:9,237,944...9,262,628
JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 affects localization ISO Sulindac affects the localization of AIFM1 protein CTD PMID:15946692, PMID:17136320 NCBI chr  X:135,304,063...135,343,062
Ensembl chr  X:135,304,066...135,343,087
JBrowse link
G Aifm2 apoptosis inducing factor, mitochondria associated 2 increases expression ISO Sulindac results in increased expression of AIFM2 mRNA CTD PMID:11906190 NCBI chr20:31,329,047...31,353,548
Ensembl chr20:31,339,787...31,352,906
JBrowse link
G Akap1 A-kinase anchoring protein 1 increases expression EXP Sulindac results in increased expression of AKAP1 mRNA CTD PMID:24136188 NCBI chr10:76,151,013...76,183,987
Ensembl chr10:76,151,038...76,166,276
JBrowse link
G Akap9 A-kinase anchoring protein 9 decreases expression EXP Sulindac results in decreased expression of AKAP9 mRNA CTD PMID:24136188 NCBI chr 4:27,195,346...27,331,582
Ensembl chr 4:27,195,346...27,331,582
JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B multiple interactions ISO Sulindac analog binds to and results in decreased activity of AKR1B1 protein; Sulindac binds to and results in decreased activity of AKR1B1 protein CTD PMID:25532697 NCBI chr 4:61,706,866...61,720,959
Ensembl chr 4:61,706,864...61,720,956
JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 multiple interactions ISO Sulindac analog binds to and results in decreased activity of AKR1B10 protein; Sulindac binds to and results in decreased activity of AKR1B10 protein CTD PMID:25532697 NCBI chr 4:61,813,265...61,830,371
Ensembl chr 4:61,771,970...61,828,657
JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 decreases activity ISO Sulindac results in decreased activity of AKR1C2 protein CTD PMID:19010312 NCBI chr17:69,388,337...69,435,160
Ensembl chr17:69,388,335...69,404,341
JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 decreases activity ISO Sulindac results in decreased activity of AKR1C3 protein CTD PMID:19010312 NCBI chr17:69,761,126...69,778,021
Ensembl chr17:69,761,118...69,778,021
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions
decreases phosphorylation
ISO
EXP
[AKT1 protein affects the reaction [Sulindac analog results in decreased expression of HIF1A protein]] which affects the susceptibility to Oxygen; AKT1 protein affects the reaction [Sulindac analog results in decreased expression of HIF1A protein]
[Sulindac co-treated with lipopolysaccharide, E coli O55-B5] affects the expression of AKT1 mRNA
Sulindac analog results in decreased phosphorylation of AKT1 protein
CTD PMID:18924134, PMID:20371263 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Akt1s1 AKT1 substrate 1 decreases expression EXP Sulindac results in decreased expression of AKT1S1 mRNA CTD PMID:24136188 NCBI chr 1:100,845,443...100,851,961
Ensembl chr 1:100,845,563...100,851,960
JBrowse link
G Akt2 AKT serine/threonine kinase 2 decreases expression
increases expression
ISO
EXP
Sulindac results in decreased expression of AKT2 mRNA
Sulindac results in increased expression of AKT2 mRNA
CTD PMID:11906190, PMID:24136188 NCBI chr 1:84,400,939...84,451,223
Ensembl chr 1:84,411,726...84,450,162
JBrowse link
G Alb albumin multiple interactions EXP [Sulindac co-treated with REN2] results in increased expression of ALB protein CTD PMID:12586211 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 multiple interactions EXP [Sulindac co-treated with lipopolysaccharide, E coli O55-B5] affects the expression of ALDH1A1 mRNA CTD PMID:20371263 NCBI chr 1:238,222,689...238,264,381
Ensembl chr 1:238,222,521...238,264,330
JBrowse link
G Aldh1l1 aldehyde dehydrogenase 1 family, member L1 multiple interactions EXP [Sulindac co-treated with lipopolysaccharide, E coli O55-B5] affects the expression of ALDH1L1 mRNA CTD PMID:20371263 NCBI chr 4:123,516,553...123,564,067
Ensembl chr 4:123,516,788...123,557,501
JBrowse link
G Aldh3a2 aldehyde dehydrogenase 3 family, member A2 decreases expression EXP Sulindac results in decreased expression of ALDH3A2 mRNA CTD PMID:24136188 NCBI chr10:47,525,486...47,546,535
Ensembl chr10:47,525,493...47,546,345
JBrowse link
G Aldh6a1 aldehyde dehydrogenase 6 family, member A1 multiple interactions EXP [Sulindac co-treated with lipopolysaccharide, E coli O55-B5] affects the expression of ALDH6A1 mRNA CTD PMID:20371263 NCBI chr 6:108,146,552...108,167,185
Ensembl chr 6:108,146,582...108,167,185
JBrowse link
G Alg14 ALG14, UDP-N-acetylglucosaminyltransferase subunit increases expression EXP Sulindac results in increased expression of ALG14 mRNA CTD PMID:24136188 NCBI chr 2:224,851,352...224,931,461
Ensembl chr 2:224,851,383...224,931,459
JBrowse link
G Alox15 arachidonate 15-lipoxygenase increases expression
multiple interactions
increases activity
ISO Sulindac results in increased expression of ALOX15 protein
[Sulindac results in increased expression of ALOX15 protein] which results in increased chemical synthesis of 13-hydroxy-9,11-octadecadienoic acid
Sulindac results in increased activity of ALOX15 protein
CTD PMID:10904086, PMID:11406566 NCBI chr10:56,953,692...56,962,145
Ensembl chr10:56,953,691...56,962,161
JBrowse link
G Alpl alkaline phosphatase, biomineralization associated multiple interactions ISO Sulindac promotes the reaction [cobaltous chloride results in decreased expression of ALPL protein]; Sulindac promotes the reaction [Deferoxamine results in decreased expression of ALPL protein] CTD PMID:21882223 NCBI chr 5:156,086,496...156,141,513
Ensembl chr 5:156,086,497...156,141,537
JBrowse link
G Amd1 adenosylmethionine decarboxylase 1 multiple interactions ISO [Sulindac co-treated with Putrescine] results in decreased activity of AMD1 protein CTD PMID:17474863 NCBI chr20:45,384,000...45,399,694
Ensembl chr20:45,384,000...45,399,694
JBrowse link
G Amt aminomethyltransferase increases expression EXP Sulindac results in increased expression of AMT mRNA CTD PMID:24136188 NCBI chr 8:117,068,388...117,078,633
Ensembl chr 8:117,068,582...117,077,913
JBrowse link
G Amz2 archaelysin family metallopeptidase 2 decreases expression EXP Sulindac results in decreased expression of AMZ2 mRNA CTD PMID:24136188 NCBI chr10:97,710,905...97,721,442
Ensembl chr10:97,710,905...97,721,440
JBrowse link
G Ankrd11 ankyrin repeat domain 11 increases expression ISO Sulindac results in increased expression of ANKRD11 mRNA CTD PMID:11906190 NCBI chr19:55,703,831...55,862,446
Ensembl chr19:55,703,824...55,737,500
JBrowse link
G Ankrd24 ankyrin repeat domain 24 increases expression EXP Sulindac results in increased expression of ANKRD24 mRNA CTD PMID:24136188 NCBI chr 7:10,917,359...10,937,522
Ensembl chr 7:10,917,367...10,936,415
JBrowse link
G Ankrd28 ankyrin repeat domain 28 decreases expression EXP Sulindac results in decreased expression of ANKRD28 mRNA CTD PMID:24136188 NCBI chr16:7,816,876...7,879,023
Ensembl chr16:7,818,667...7,928,518
JBrowse link
G Ap1ar adaptor-related protein complex 1 associated regulatory protein increases expression EXP Sulindac results in increased expression of AP1AR mRNA CTD PMID:24136188 NCBI chr 2:232,146,418...232,178,813
Ensembl chr 2:232,147,690...232,178,671
JBrowse link
G Ap3d1 adaptor related protein complex 3 subunit delta 1 increases expression EXP Sulindac results in increased expression of AP3D1 mRNA CTD PMID:24136188 NCBI chr 7:11,838,639...11,873,992
Ensembl chr 7:11,838,639...11,873,984
JBrowse link
G Apc APC regulator of WNT signaling pathway multiple interactions
increases expression
EXP Sulindac inhibits the reaction [Azoxymethane results in decreased expression of APC mRNA]
Sulindac results in increased expression of APC protein
CTD PMID:11076880, PMID:12458338 NCBI chr18:27,011,710...27,106,323
Ensembl chr18:27,047,382...27,105,531
JBrowse link
G App amyloid beta precursor protein multiple interactions ISO Sulindac inhibits the reaction [CDKN1A protein results in increased expression of APP mRNA] CTD PMID:15190207 NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858
JBrowse link
G Aqp1 aquaporin 1 decreases expression EXP Sulindac results in decreased expression of AQP1 mRNA CTD PMID:24136188 NCBI chr 4:85,551,503...85,563,683
Ensembl chr 4:85,551,502...85,569,360
JBrowse link
G Arglu1 arginine and glutamate rich 1 increases expression ISO Sulindac results in increased expression of ARGLU1 mRNA CTD PMID:11906190 NCBI chr16:86,600,877...86,625,084
Ensembl chr16:86,600,877...86,625,083
JBrowse link
G Arid1b AT-rich interaction domain 1B decreases expression EXP Sulindac results in decreased expression of ARID1B mRNA CTD PMID:24136188 NCBI chr 1:45,923,119...46,232,301
Ensembl chr 1:45,923,222...46,234,874
JBrowse link
G Arl1 ADP-ribosylation factor like GTPase 1 increases expression EXP Sulindac results in increased expression of ARL1 mRNA CTD PMID:24136188 NCBI chr 7:29,282,411...29,293,455
Ensembl chr 7:29,282,305...29,293,399
JBrowse link
G Arrdc3 arrestin domain containing 3 increases expression ISO Sulindac results in increased expression of ARRDC3 mRNA CTD PMID:11906190 NCBI chr 2:8,732,907...8,745,445
Ensembl chr 2:8,732,932...8,743,069
JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) increases expression ISO Sulindac results in increased expression of ASNS mRNA CTD PMID:11906190 NCBI chr 4:33,742,876...33,761,106
Ensembl chr 4:33,743,364...33,761,163
JBrowse link
G Asnsd1 asparagine synthetase domain containing 1 increases expression EXP Sulindac results in increased expression of ASNSD1 mRNA CTD PMID:24136188 NCBI chr 9:52,988,042...53,009,054
Ensembl chr 9:53,004,499...53,009,054
JBrowse link
G Ate1 arginyltransferase 1 decreases expression EXP Sulindac results in decreased expression of ATE1 mRNA CTD PMID:24136188 NCBI chr 1:200,810,741...200,885,593
NCBI chr 1:200,958,564...201,082,100
Ensembl chr 1:200,810,771...201,082,727
JBrowse link
G Atf3 activating transcription factor 3 increases expression ISO Sulindac results in increased expression of ATF3 mRNA CTD PMID:11906190 NCBI chr13:109,817,892...109,849,632
Ensembl chr13:109,817,728...109,849,632
JBrowse link
G Atf4 activating transcription factor 4 increases expression ISO Sulindac results in increased expression of ATF4 mRNA CTD PMID:11906190 NCBI chr 7:121,480,723...121,482,781
Ensembl chr 7:121,480,723...121,482,772
JBrowse link
G Atg3 autophagy related 3 increases expression EXP Sulindac results in increased expression of ATG3 mRNA CTD PMID:24136188 NCBI chr11:60,585,192...60,613,706
Ensembl chr11:60,585,171...60,613,718
JBrowse link
G Atp2a1 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 decreases expression ISO Sulindac results in decreased expression of ATP2A1 mRNA CTD PMID:11906190 NCBI chr 1:197,855,912...197,875,038 JBrowse link
G Atp6v1a ATPase H+ transporting V1 subunit A increases expression EXP Sulindac results in increased expression of ATP6V1A mRNA CTD PMID:24136188 NCBI chr11:61,531,386...61,584,634
Ensembl chr11:61,531,416...61,584,634
JBrowse link
G Atp6v1e1 ATPase H+ transporting V1 subunit E1 increases expression EXP Sulindac results in increased expression of ATP6V1E1 mRNA CTD PMID:24136188 NCBI chr 4:153,351,434...153,373,558
Ensembl chr 4:153,351,421...153,373,649
JBrowse link
G Auh AU RNA binding methylglutaconyl-CoA hydratase multiple interactions EXP [Sulindac co-treated with lipopolysaccharide, E coli O55-B5] affects the expression of AUH mRNA CTD PMID:20371263 NCBI chr17:12,310,178...12,405,224
Ensembl chr17:12,310,214...12,405,205
JBrowse link
G Aurka aurora kinase A decreases expression ISO Sulindac results in decreased expression of AURKA mRNA CTD PMID:11906190 NCBI chr 3:170,364,177...170,380,278
Ensembl chr 3:170,364,181...170,378,210
JBrowse link
G Aurkaip1 aurora kinase A interacting protein 1 decreases expression EXP Sulindac results in decreased expression of AURKAIP1 mRNA CTD PMID:24136188 NCBI chr 5:173,274,433...173,276,170
Ensembl chr 5:173,256,637...173,276,169
JBrowse link
G B4galt1 beta-1,4-galactosyltransferase 1 decreases expression EXP Sulindac results in decreased expression of B4GALT1 mRNA CTD PMID:24136188 NCBI chr 5:57,121,768...57,168,610
Ensembl chr 5:57,121,769...57,168,610
JBrowse link
G Bad BCL2-associated agonist of cell death multiple interactions
decreases expression
ISO Sulindac inhibits the reaction [EGF protein results in increased phosphorylation of BAD protein]
Sulindac results in decreased expression of BAD protein
CTD PMID:12566304 NCBI chr 1:222,198,516...222,207,459
Ensembl chr 1:222,198,534...222,207,453
JBrowse link
G Bak1 BCL2-antagonist/killer 1 multiple interactions
affects localization
ISO SB 203580 inhibits the reaction [Sulindac affects the localization of BAK1 protein] CTD PMID:17136320 NCBI chr20:5,609,620...5,618,899
Ensembl chr20:5,609,625...5,618,260
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions
increases expression
affects localization
increases response to substance
ISO SB 203580 inhibits the reaction [Sulindac affects the localization of BAX protein]
Sulindac results in increased expression of BAX protein
BAX protein results in increased susceptibility to Sulindac
CTD PMID:11062132, PMID:17136320 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bbc3 Bcl-2 binding component 3 increases expression ISO Sulindac results in increased expression of BBC3 mRNA CTD PMID:11906190 NCBI chr 1:78,261,491...78,267,802 JBrowse link
G Bcap29 B-cell receptor-associated protein 29 increases expression ISO Sulindac results in increased expression of BCAP29 mRNA CTD PMID:11906190 NCBI chr 6:50,883,758...50,923,743
Ensembl chr 6:50,883,787...50,923,510
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression
multiple interactions
ISO
EXP
Sulindac results in decreased expression of BCL2 protein
[Olive Oil co-treated with Sulindac] results in decreased expression of BCL2 protein
[Sulindac results in increased abundance of Reactive Oxygen Species] which results in increased cleavage of BCL2 protein
CTD PMID:10223192, PMID:15309441, PMID:15793875, PMID:17136320 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bcl2l1 Bcl2-like 1 multiple interactions
decreases expression
ISO [Sulindac co-treated with arsenic trioxide] results in increased phosphorylation of BCL2L1 protein; Acetylcysteine inhibits the reaction [[Sulindac co-treated with arsenic trioxide] results in increased phosphorylation of BCL2L1 protein]; MAPK8 affects the reaction [[Sulindac co-treated with arsenic trioxide] results in increased phosphorylation of BCL2L1 protein]; pyrazolanthrone inhibits the reaction [[Sulindac co-treated with arsenic trioxide] results in increased phosphorylation of BCL2L1 protein]
Sulindac results in decreased expression of BCL2L1 protein
CTD PMID:11062132, PMID:18281123 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
JBrowse link
G Birc2 baculoviral IAP repeat-containing 2 multiple interactions ISO [Sulindac results in increased abundance of Reactive Oxygen Species] which results in decreased expression of BIRC2 protein CTD PMID:17136320 NCBI chr 8:6,014,014...6,036,668
Ensembl chr 8:6,013,207...6,034,142
JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 multiple interactions ISO [Sulindac results in increased abundance of Reactive Oxygen Species] which results in decreased expression of BIRC3 protein CTD PMID:17136320 NCBI chr 8:6,048,590...6,076,828
Ensembl chr 8:6,048,969...6,076,598
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 multiple interactions
decreases expression
ISO [Sulindac co-treated with Arsenic Trioxide] results in decreased expression of BIRC5 protein; [Sulindac co-treated with Vorinostat] results in decreased expression of BIRC5 mRNA; [Sulindac co-treated with Vorinostat] results in decreased expression of BIRC5 protein; [Sulindac results in increased abundance of Reactive Oxygen Species] which results in decreased expression of BIRC5 protein; BIRC5 protein inhibits the reaction [Sulindac results in decreased expression of STAT3 protein modified form]; BIRC5 protein inhibits the reaction [Sulindac results in decreased expression of STAT3 protein]
Sulindac results in decreased expression of BIRC5 mRNA; Sulindac results in decreased expression of BIRC5 protein
CTD PMID:11906190, PMID:14610217, PMID:17136320, PMID:17401459, PMID:18156316, PMID:18281123 NCBI chr10:106,856,097...106,864,419
Ensembl chr10:106,856,097...106,864,413
JBrowse link
G Blmh bleomycin hydrolase increases expression EXP Sulindac results in increased expression of BLMH mRNA CTD PMID:24136188 NCBI chr10:63,197,367...63,240,447
Ensembl chr10:63,197,364...63,240,332
JBrowse link
G Bnip3l BCL2 interacting protein 3 like increases expression EXP Sulindac results in increased expression of BNIP3L mRNA CTD PMID:24136188 NCBI chr15:43,643,897...43,667,123
Ensembl chr15:43,643,897...43,667,029
JBrowse link
G Borcs7 BLOC-1 related complex subunit 7 increases expression EXP Sulindac results in increased expression of BORCS7 mRNA CTD PMID:24136188 NCBI chr 1:266,451,021...266,464,903
Ensembl chr 1:266,451,021...266,464,903
JBrowse link
G Brca1 BRCA1, DNA repair associated decreases expression ISO Sulindac results in decreased expression of BRCA1 mRNA CTD PMID:16273229 NCBI chr10:89,394,821...89,455,093
Ensembl chr10:89,394,803...89,454,681
JBrowse link
G Brd4 bromodomain containing 4 decreases expression ISO Sulindac results in decreased expression of BRD4 mRNA CTD PMID:11906190 NCBI chr 7:14,222,101...14,303,055
Ensembl chr 7:14,222,101...14,303,055
JBrowse link
G Btbd1 BTB domain containing 1 increases expression EXP Sulindac results in increased expression of BTBD1 mRNA CTD PMID:24136188 NCBI chr 1:143,609,729...143,647,124
Ensembl chr 1:143,609,731...143,647,124
JBrowse link
G Bzw1 basic leucine zipper and W2 domains 1 increases expression EXP Sulindac results in increased expression of BZW1 mRNA CTD PMID:24136188 NCBI chr 9:65,279,675...65,293,471
Ensembl chr 9:65,279,675...65,291,651
JBrowse link
G Bzw2 basic leucine zipper and W2 domains 2 decreases expression ISO Sulindac results in decreased expression of BZW2 mRNA CTD PMID:11093808 NCBI chr 6:55,586,754...55,647,650
Ensembl chr 6:55,586,346...55,647,665
JBrowse link
G C1galt1c1 C1GALT1-specific chaperone 1 decreases expression EXP Sulindac results in decreased expression of C1GALT1C1 mRNA CTD PMID:24136188 NCBI chr  X:124,921,686...124,926,171
Ensembl chr  X:124,921,728...124,926,171
JBrowse link
G C4b complement C4B (Chido blood group) decreases expression EXP Sulindac results in decreased expression of C4B mRNA CTD PMID:24136188 NCBI chr20:4,302,344...4,316,752
Ensembl chr20:4,302,344...4,316,715
JBrowse link
G Ca9 carbonic anhydrase 9 decreases expression ISO Sulindac analog results in decreased expression of CA9 mRNA CTD PMID:18924134 NCBI chr 5:59,008,277...59,015,535
Ensembl chr 5:59,008,933...59,015,528
JBrowse link
G Calm3 calmodulin 3 decreases expression
increases expression
ISO
EXP
Sulindac results in decreased expression of CALM3 mRNA
Sulindac results in increased expression of CALM3 mRNA
CTD PMID:11906190, PMID:24136188 NCBI chr 1:78,844,520...78,851,628
Ensembl chr 1:78,843,080...78,851,719
JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity
increases expression
ISO
EXP
[Sulindac co-treated with arsenic trioxide] results in increased activity of CASP3 protein; Acetylcysteine inhibits the reaction [[Sulindac co-treated with arsenic trioxide] results in increased activity of CASP3 protein]; pyrazolanthrone inhibits the reaction [[Sulindac co-treated with arsenic trioxide] results in increased activity of CASP3 protein]
epigallocatechin gallate promotes the reaction [Sulindac inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of CASP3 protein]]; kaempferol promotes the reaction [Sulindac inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of CASP3 protein]]; Sulindac inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of CASP3 protein]
Sulindac results in increased activity of CASP3 protein
[Sulindac results in increased expression of IL24 protein] which results in increased expression of CASP3 protein
CTD PMID:12017300, PMID:15713900, PMID:15946692, PMID:18281123, PMID:29999212 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp8 caspase 8 multiple interactions ISO [Sulindac co-treated with TNFSF10 protein] results in increased activity of CASP8 protein CTD PMID:21171083 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Casp9 caspase 9 multiple interactions
increases expression
increases activity
ISO [Sulindac co-treated with arsenic trioxide] results in increased activity of CASP9 protein
[Sulindac results in increased expression of IL24 protein] which results in increased expression of CASP9 protein
Sulindac results in increased activity of CASP9 protein
CTD PMID:15713900, PMID:18281123 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cast calpastatin decreases expression EXP Sulindac results in decreased expression of CAST mRNA CTD PMID:24136188 NCBI chr 2:1,452,111...1,561,669
Ensembl chr 2:1,452,116...1,561,464
JBrowse link
G Cavin3 caveolae associated protein 3 increases expression ISO Sulindac results in increased expression of CAVIN3 mRNA CTD PMID:11906190 NCBI chr 1:170,317,099...170,318,688
Ensembl chr 1:170,317,113...170,318,935
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 multiple interactions ISO Sulindac inhibits the reaction [IL1B protein results in increased expression of CCL5 mRNA]; Sulindac inhibits the reaction [TNF protein results in increased expression of CCL5 mRNA] CTD PMID:16159934 NCBI chr10:70,739,764...70,744,303
Ensembl chr10:70,739,800...70,744,315
JBrowse link
G Ccna2 cyclin A2 decreases expression ISO Sulindac results in decreased expression of CCNA2 protein CTD PMID:16488075 NCBI chr 2:123,274,727...123,282,266
Ensembl chr 2:123,275,881...123,282,214
JBrowse link
G Ccnb1 cyclin B1 decreases expression ISO Sulindac results in decreased expression of CCNB1 mRNA CTD PMID:11906190 NCBI chr 2:30,782,133...30,791,106
Ensembl chr 2:30,783,915...30,791,221
JBrowse link
G Ccnd1 cyclin D1 multiple interactions
decreases expression
ISO CTNNB1 protein affects the reaction [Sulindac results in decreased expression of CCND1 protein]; Sulindac inhibits the reaction [TNF protein results in increased expression of CCND1 protein]
[Sulindac co-treated with Plant Extracts] results in decreased expression of CCND1 protein
CTD PMID:11504793, PMID:11593435, PMID:12351151, PMID:12584176, PMID:15020200, PMID:15489888, PMID:17292881, PMID:18291362 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Ccne1 cyclin E1 decreases expression ISO Sulindac results in decreased expression of CCNE1 protein CTD PMID:16488075 NCBI chr 1:94,485,830...94,495,112
Ensembl chr 1:94,485,832...94,494,980
JBrowse link
G Ccnj cyclin J decreases expression ISO Sulindac results in decreased expression of CCNJ mRNA CTD PMID:11906190 NCBI chr 1:259,926,537...259,944,275
Ensembl chr 1:260,093,641...260,111,254
Ensembl chr 1:260,093,641...260,111,254
JBrowse link
G Ccnq cyclin Q decreases expression EXP Sulindac results in decreased expression of CCNQ mRNA CTD PMID:24136188 NCBI chr10:66,019,519...66,020,682
Ensembl chr10:66,019,520...66,020,682
JBrowse link
G Cct4 chaperonin containing TCP1 subunit 4 decreases expression EXP Sulindac results in decreased expression of CCT4 mRNA CTD PMID:24136188 NCBI chr14:107,767,392...107,780,270
Ensembl chr14:107,767,392...107,780,270
JBrowse link
G Ccz1b CCZ1 homolog B, vacuolar protein trafficking and biogenesis associated increases expression EXP Sulindac results in increased expression of CCZ1B mRNA CTD PMID:24136188 NCBI chr12:12,638,849...12,662,371
Ensembl chr12:12,638,864...12,662,371
JBrowse link
G Cdc37l1 cell division cycle 37-like 1 decreases expression EXP Sulindac results in decreased expression of CDC37L1 mRNA CTD PMID:24136188 NCBI chr 1:247,110,147...247,139,113
Ensembl chr 1:247,107,397...247,138,155
JBrowse link
G Cdc42ep1 CDC42 effector protein 1 increases expression ISO Sulindac results in increased expression of CDC42EP1 mRNA CTD PMID:11906190 NCBI chr 7:120,063,256...120,071,154
Ensembl chr 7:120,067,379...120,071,440
JBrowse link
G Cdk1 cyclin-dependent kinase 1 decreases expression ISO Sulindac results in decreased expression of CDK1 mRNA CTD PMID:16273229 NCBI chr20:20,576,341...20,591,510
Ensembl chr20:20,576,377...20,591,549
JBrowse link
G Cdk2 cyclin dependent kinase 2 multiple interactions
decreases activity
ISO Sulindac promotes the reaction [CDKN1A protein results in decreased activity of CDK2 protein]
Sulindac results in decreased activity of CDK2 protein
CTD PMID:14566837 NCBI chr 7:3,124,953...3,132,533
Ensembl chr 7:3,124,954...3,132,457
JBrowse link
G Cdk4 cyclin-dependent kinase 4 multiple interactions
decreases expression
ISO
EXP
CTNNB1 protein affects the reaction [Sulindac results in decreased expression of CDK4 protein]
[Sulindac co-treated with lipopolysaccharide, E coli O55-B5] affects the expression of CDK4 mRNA
CTD PMID:17292881, PMID:18291362, PMID:20371263 NCBI chr 7:70,345,971...70,352,689
Ensembl chr 7:70,349,863...70,352,418
JBrowse link
G Cdk6 cyclin-dependent kinase 6 decreases expression ISO Sulindac results in decreased expression of CDK6 protein CTD PMID:16488075 NCBI chr 4:27,781,728...27,969,653
Ensembl chr 4:27,785,647...27,966,398
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions
increases expression
increases response to substance
increases activity
decreases activity
ISO
EXP
[Sulindac co-treated with epigallocatechin gallate] results in increased expression of CDKN1A mRNA; CDKN1A protein promotes the reaction [Sulindac results in increased expression of and results in increased phosphorylation of MAPK8 protein]; CSK protein affects the reaction [Sulindac results in increased expression of CDKN1A protein]; Sulindac inhibits the reaction [CDKN1A protein results in increased expression of APP mRNA]; Sulindac inhibits the reaction [CDKN1A protein results in increased expression of CTSB mRNA]; Sulindac inhibits the reaction [CDKN1A protein results in increased expression of GBA mRNA]; Sulindac inhibits the reaction [CDKN1A protein results in increased expression of GRN mRNA]; Sulindac inhibits the reaction [CDKN1A protein results in increased expression of IL32 mRNA]; Sulindac inhibits the reaction [CDKN1A protein results in increased expression of ITGB3 mRNA]; Sulindac inhibits the reaction [CDKN1A protein results in increased expression of LGALS3 mRNA]; Sulindac inhibits the reaction [CDKN1A protein results in increased expression of LGALS3BP mRNA]; Sulindac inhibits the reaction [CDKN1A protein results in increased expression of SAA1 mRNA]; Sulindac inhibits the reaction [CDKN1A protein results in increased expression of SHC1 mRNA]; Sulindac inhibits the reaction [CDKN1A protein results in increased expression of SOD2 mRNA]; Sulindac inhibits the reaction [CDKN1A protein results in increased expression of TGM2 mRNA]; Sulindac promotes the reaction [CDKN1A protein results in decreased activity of CDK2 protein]
Sulindac results in increased expression of CDKN1A mRNA; Sulindac results in increased expression of CDKN1A protein
[Azoxymethane co-treated with Sulindac] results in increased expression of CDKN1A protein
CDKN1A protein results in increased susceptibility to Sulindac
Sulindac results in increased activity of CDKN1A protein
Sulindac results in decreased activity of CDKN1A protein
CTD PMID:11507085, PMID:12628509, PMID:14566837, PMID:15190207, PMID:15688007, PMID:16230399, PMID:17292881, PMID:18291362, PMID:18644992 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B multiple interactions EXP Sulindac inhibits the reaction [Azoxymethane results in decreased expression of CDKN1B protein] CTD PMID:12189186 NCBI chr 4:168,689,043...168,694,159
Ensembl chr 4:168,689,163...168,693,964
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A multiple interactions EXP Sulindac inhibits the reaction [Azoxymethane results in decreased expression of CDKN2A mRNA] CTD PMID:12189186 NCBI chr 5:107,823,323...107,832,405
Ensembl chr 5:107,823,330...107,841,175
JBrowse link
G Cfl2 cofilin 2 decreases expression EXP Sulindac results in decreased expression of CFL2 mRNA CTD PMID:24136188 NCBI chr 6:75,759,140...75,763,185
Ensembl chr 6:75,759,140...75,763,185
JBrowse link
G Chchd3 coiled-coil-helix-coiled-coil-helix domain containing 3 decreases expression EXP Sulindac results in decreased expression of CHCHD3 mRNA CTD PMID:24136188 NCBI chr 4:60,080,536...60,358,592
Ensembl chr 4:60,080,538...60,358,562
JBrowse link
G Chchd5 coiled-coil-helix-coiled-coil-helix domain containing 5 increases expression EXP Sulindac results in increased expression of CHCHD5 mRNA CTD PMID:24136188 NCBI chr 3:121,659,962...121,664,286
Ensembl chr 3:121,660,110...121,664,496
JBrowse link
G Chd8 chromodomain helicase DNA binding protein 8 decreases expression EXP Sulindac results in decreased expression of CHD8 mRNA CTD PMID:24136188 NCBI chr15:28,612,932...28,672,574
Ensembl chr15:28,612,932...28,672,569
JBrowse link
G Chmp2a charged multivesicular body protein 2A decreases expression EXP Sulindac results in decreased expression of CHMP2A mRNA CTD PMID:24136188 NCBI chr 1:65,540,808...65,543,708
Ensembl chr 1:65,541,322...65,543,707
JBrowse link
G Chrac1 chromatin accessibility complex subunit 1 increases expression EXP Sulindac results in increased expression of CHRAC1 mRNA CTD PMID:24136188 NCBI chr 7:114,323,542...114,326,930
Ensembl chr 7:114,323,542...114,326,930
JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex multiple interactions ISO Sulindac inhibits the reaction [TNF protein results in increased activity of CHUK protein] CTD PMID:15489888 NCBI chr 1:263,848,829...263,884,354
Ensembl chr 1:263,848,884...263,885,169
JBrowse link
G Clpp caseinolytic mitochondrial matrix peptidase proteolytic subunit increases expression EXP Sulindac results in increased expression of CLPP mRNA CTD PMID:24136188 NCBI chr 9:10,048,715...10,056,068
Ensembl chr 9:10,048,886...10,054,359
JBrowse link
G Clu clusterin affects expression ISO Sulindac affects the expression of CLU protein CTD PMID:12388792 NCBI chr15:42,626,612...42,665,858
Ensembl chr15:42,640,146...42,665,857
JBrowse link
G Cmtm6 CKLF-like MARVEL transmembrane domain containing 6 increases expression EXP Sulindac results in increased expression of CMTM6 mRNA CTD PMID:24136188 NCBI chr 8:122,789,208...122,807,560
Ensembl chr 8:122,789,453...122,807,560
JBrowse link
G Cngb1 cyclic nucleotide gated channel subunit beta 1 decreases expression EXP Sulindac results in decreased expression of CNGB1 mRNA CTD PMID:24136188 NCBI chr19:10,142,440...10,206,618
Ensembl chr19:10,142,496...10,206,681
JBrowse link
G Cnnm4 cyclin and CBS domain divalent metal cation transport mediator 4 increases expression ISO Sulindac results in increased expression of CNNM4 mRNA CTD PMID:11906190 NCBI chr 9:43,049,587...43,088,690
Ensembl chr 9:43,049,587...43,088,702
JBrowse link
G Cnot6 CCR4-NOT transcription complex, subunit 6 decreases expression EXP Sulindac results in decreased expression of CNOT6 mRNA CTD PMID:24136188 NCBI chr10:35,144,291...35,195,126
Ensembl chr10:35,146,337...35,187,416
JBrowse link
G Col1a2 collagen type I alpha 2 chain increases expression ISO Sulindac results in increased expression of COL1A2 mRNA CTD PMID:18499699 NCBI chr 4:31,534,225...31,569,152
Ensembl chr 4:31,534,225...31,569,151
JBrowse link
G Col5a2 collagen type V alpha 2 chain increases expression ISO Sulindac results in increased expression of COL5A2 mRNA CTD PMID:18499699 NCBI chr 9:52,091,088...52,238,735
Ensembl chr 9:52,092,511...52,238,564
JBrowse link
G Col6a2 collagen type VI alpha 2 chain increases expression ISO Sulindac results in increased expression of COL6A2 mRNA CTD PMID:18499699 NCBI chr20:12,773,472...12,801,179
Ensembl chr20:12,773,427...12,801,180
JBrowse link
G Col6a3 collagen type VI alpha 3 chain increases expression ISO Sulindac results in increased expression of COL6A3 mRNA CTD PMID:18499699 NCBI chr 9:97,926,784...98,004,643
Ensembl chr 9:97,926,787...98,004,546
JBrowse link
G Commd3 COMM domain containing 3 increases expression EXP Sulindac results in increased expression of COMMD3 mRNA CTD PMID:24136188 NCBI chr17:85,356,042...85,359,835
Ensembl chr17:85,356,042...85,359,833
JBrowse link
G Commd5 COMM domain containing 5 increases expression EXP Sulindac results in increased expression of COMMD5 mRNA CTD PMID:24136188 NCBI chr 7:117,963,213...117,965,010
Ensembl chr 7:118,502,676...118,504,097
Ensembl chr 7:118,502,676...118,504,097
JBrowse link
G Cops7a COP9 signalosome subunit 7A increases expression EXP Sulindac results in increased expression of COPS7A mRNA CTD PMID:24136188 NCBI chr 4:157,479,549...157,486,944
Ensembl chr 4:157,479,549...157,486,914
JBrowse link
G Cox15 cytochrome c oxidase assembly homolog COX15 increases expression EXP Sulindac results in increased expression of COX15 mRNA CTD PMID:24136188 NCBI chr 1:263,494,850...263,511,510
Ensembl chr 1:263,494,852...263,511,505
JBrowse link
G Cpne1 copine 1 decreases expression ISO Sulindac results in decreased expression of CPNE1 mRNA CTD PMID:11906190 NCBI chr 3:151,617,733...151,625,448
NCBI chr 3:152,150,143...152,192,936
Ensembl chr 3:151,616,037...151,625,644
Ensembl chr 3:151,616,037...151,625,644
JBrowse link
G Cpsf3 cleavage and polyadenylation specific factor 3 increases expression EXP Sulindac results in increased expression of CPSF3 mRNA CTD PMID:24136188 NCBI chr 6:43,363,792...43,391,712
Ensembl chr 6:43,363,792...43,391,712
JBrowse link
G Creb3l3 cAMP responsive element binding protein 3-like 3 increases expression EXP Sulindac results in increased expression of CREB3L3 mRNA CTD PMID:24136188 NCBI chr 7:11,490,852...11,499,287
Ensembl chr 7:11,490,852...11,499,282
JBrowse link
G Crebzf CREB/ATF bZIP transcription factor increases expression EXP Sulindac results in increased expression of CREBZF mRNA CTD PMID:24136188 NCBI chr 1:156,290,215...156,296,891
Ensembl chr 1:156,294,519...156,296,161
JBrowse link
G Cry2 cryptochrome circadian regulator 2 decreases expression EXP Sulindac results in decreased expression of CRY2 mRNA CTD PMID:24136188 NCBI chr 3:81,314,151...81,344,143
Ensembl chr 3:81,314,149...81,344,110
JBrowse link
G Csf1 colony stimulating factor 1 decreases expression EXP Sulindac results in decreased expression of CSF1 mRNA CTD PMID:24136188 NCBI chr 2:210,522,370...210,550,546
Ensembl chr 2:210,522,375...210,550,560
JBrowse link
G Csk C-terminal Src kinase multiple interactions ISO
EXP
CSK protein affects the reaction [Sulindac results in increased expression of CDKN1A protein]
[[Azoxymethane co-treated with Sulindac] results in increased expression of CSK protein] which results in increased phosphorylation of and results in decreased activity of SRC protein; [Azoxymethane co-treated with Sulindac] results in increased expression of CSK protein
CTD PMID:18644992 NCBI chr 8:62,405,714...62,424,707
Ensembl chr 8:62,405,715...62,424,303
JBrowse link
G Csnk2a1 casein kinase 2 alpha 1 decreases expression
increases expression
ISO
EXP
Sulindac results in decreased expression of CSNK2A1 mRNA
Sulindac results in increased expression of CSNK2A1 mRNA
CTD PMID:11906190, PMID:24136188 NCBI chr 3:147,713,808...147,760,375
Ensembl chr 3:147,713,821...147,757,862
JBrowse link
G Csnk2a2 casein kinase 2 alpha 2 increases expression ISO Sulindac results in increased expression of CSNK2A2 mRNA CTD PMID:11906190 NCBI chr19:9,972,537...10,012,043
Ensembl chr19:9,972,537...10,012,043
JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions
decreases expression
ISO
EXP
CTNNB1 protein affects the reaction [Sulindac results in decreased expression of CCND1 protein]; CTNNB1 protein affects the reaction [Sulindac results in decreased expression of CDK4 protein]; CTNNB1 protein affects the reaction [Sulindac results in decreased expression of MYC protein]; Sulindac results in decreased activity of [LEF1 protein binds to CTNNB1 protein]
epigallocatechin gallate promotes the reaction [Sulindac inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of CTNNB1 protein]]; kaempferol promotes the reaction [Sulindac inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of CTNNB1 protein]]; Sulindac inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of CTNNB1 protein]
Sulindac results in decreased expression of CTNNB1 protein
[Sulindac co-treated with Plant Extracts] results in decreased expression of CTNNB1 protein
CTD PMID:10223192, PMID:11751639, PMID:12351151, PMID:18291362, PMID:29999212 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372
JBrowse link
G Ctsb cathepsin B multiple interactions ISO Sulindac inhibits the reaction [CDKN1A protein results in increased expression of CTSB mRNA] CTD PMID:15190207 NCBI chr15:46,316,741...46,337,613
Ensembl chr15:46,316,741...46,337,612
JBrowse link
G Cxcl9 C-X-C motif chemokine ligand 9 multiple interactions ISO Sulindac inhibits the reaction [IFNG protein results in increased expression of CXCL9 mRNA] CTD PMID:17010317 NCBI chr14:17,228,832...17,233,743
Ensembl chr14:17,228,856...17,234,712
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression
increases activity
ISO
EXP
Sulindac results in increased expression of CYP1A1 mRNA
Sulindac results in increased activity of CYP1A1 protein
CTD PMID:16531450, PMID:17985343 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression
decreases expression
ISO
EXP
Sulindac results in increased expression of CYP1A2 mRNA
Sulindac results in decreased expression of CYP1A2 mRNA
CTD PMID:16531450, PMID:17985343, PMID:24136188 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 increases expression
increases activity
ISO
EXP
Sulindac results in increased expression of CYP1B1 mRNA
Sulindac results in increased activity of CYP1B1 protein
CTD PMID:16531450, PMID:17985343 NCBI chr 6:2,308,179...2,316,739
Ensembl chr 6:2,307,808...2,316,722
JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 multiple interactions EXP [Sulindac co-treated with lipopolysaccharide, E coli O55-B5] affects the expression of CYP2D4 mRNA CTD PMID:20371263 NCBI chr 7:123,599,264...123,608,436
Ensembl chr 7:123,599,266...123,608,436
JBrowse link
G Cyp2j4 cytochrome P450, family 2, subfamily j, polypeptide 4 multiple interactions EXP [Sulindac co-treated with lipopolysaccharide, E coli O55-B5] affects the expression of CYP2J4 mRNA CTD PMID:20371263 NCBI chr 5:119,546,458...119,564,843
Ensembl chr 5:119,546,461...119,564,846
JBrowse link
G Cyp4b1 cytochrome P450, family 4, subfamily b, polypeptide 1 multiple interactions EXP [Sulindac co-treated with lipopolysaccharide, E coli O55-B5] affects the expression of CYP4B1 mRNA CTD PMID:20371263 NCBI chr 5:134,508,728...134,526,103
Ensembl chr 5:134,508,730...134,526,089
JBrowse link
G Cyp8b1 cytochrome P450 family 8 subfamily B member 1 multiple interactions EXP [Sulindac co-treated with lipopolysaccharide, E coli O55-B5] affects the expression of CYP8B1 mRNA CTD PMID:20371263 NCBI chr 8:130,548,418...130,550,388
Ensembl chr 8:130,548,418...130,550,388
JBrowse link
G Dcn decorin decreases expression ISO Sulindac results in decreased expression of DCN mRNA CTD PMID:11507085 NCBI chr 7:38,742,250...38,782,282
Ensembl chr 7:38,742,051...38,782,323
JBrowse link
G Dctn5 dynactin subunit 5 decreases expression EXP Sulindac results in decreased expression of DCTN5 mRNA CTD PMID:24136188 NCBI chr 1:192,088,709...192,105,421
Ensembl chr 1:192,088,672...192,105,429
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions
increases expression
ISO [Sulindac co-treated with epigallocatechin gallate] results in increased expression of DDIT3 mRNA
Sulindac results in increased expression of DDIT3 mRNA
CTD PMID:12628509, PMID:24136188 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
JBrowse link
G Ddx1 DEAD-box helicase 1 decreases expression EXP Sulindac results in decreased expression of DDX1 mRNA CTD PMID:24136188 NCBI chr 6:38,422,892...38,453,762
Ensembl chr 6:38,422,888...38,453,797
JBrowse link
G Degs1 delta(4)-desaturase, sphingolipid 1 increases expression EXP Sulindac results in increased expression of DEGS1 mRNA CTD PMID:24136188 NCBI chr13:100,665,265...100,672,731
Ensembl chr13:100,666,075...100,672,731
JBrowse link
G Dffb DNA fragmentation factor subunit beta affects localization ISO Sulindac affects the localization of DFFB protein CTD PMID:15946692 NCBI chr 5:171,250,559...171,261,875
Ensembl chr 5:171,249,633...171,262,119
JBrowse link
G Dhrs11 dehydrogenase/reductase 11 decreases activity ISO Sulindac results in decreased activity of DHRS11 protein CTD PMID:30926317 NCBI chr10:72,144,042...72,153,496
Ensembl chr10:72,144,042...72,153,375
JBrowse link
G Dhx36 DEAH-box helicase 36 increases expression EXP Sulindac results in increased expression of DHX36 mRNA CTD PMID:24136188 NCBI chr 2:152,785,844...152,824,549
Ensembl chr 2:152,785,844...152,824,547
JBrowse link
G Dip2c disco-interacting protein 2 homolog C increases expression EXP Sulindac results in increased expression of DIP2C mRNA CTD PMID:24136188 NCBI chr17:63,426,688...63,810,183
Ensembl chr17:63,635,086...63,808,464
JBrowse link
G Dlg1 discs large MAGUK scaffold protein 1 increases expression EXP Sulindac results in increased expression of DLG1 mRNA CTD PMID:24136188 NCBI chr11:72,164,566...72,378,895
Ensembl chr11:72,163,749...72,378,895
JBrowse link
G Dnajc10 DnaJ heat shock protein family (Hsp40) member C10 increases expression EXP Sulindac results in increased expression of DNAJC10 mRNA CTD PMID:24136188 NCBI chr 3:67,538,289...67,578,308
Ensembl chr 3:67,538,289...67,578,306
JBrowse link
G Dnajc15 DnaJ heat shock protein family (Hsp40) member C15 increases expression EXP Sulindac results in increased expression of DNAJC15 mRNA CTD PMID:24136188 NCBI chr15:59,990,131...60,056,710
Ensembl chr15:59,990,131...60,056,710
JBrowse link
G Dpys dihydropyrimidinase increases expression ISO Sulindac results in increased expression of DPYS mRNA CTD PMID:11906190 NCBI chr 7:78,769,918...78,847,941
Ensembl chr 7:78,769,807...78,847,974
JBrowse link
G Dynll1 dynein light chain LC8-type 1 decreases expression EXP Sulindac results in decreased expression of DYNLL1 mRNA CTD PMID:24136188 NCBI chr12:47,074,200...47,076,573
Ensembl chr12:47,074,200...47,076,572
JBrowse link
G E2f1 E2F transcription factor 1 decreases expression ISO Sulindac results in decreased expression of E2F1 protein CTD PMID:16488075 NCBI chr 3:150,062,895...150,073,721
Ensembl chr 3:150,047,826...150,073,721
JBrowse link
G Eci2 enoyl-CoA delta isomerase 2 multiple interactions EXP [Sulindac co-treated with lipopolysaccharide, E coli O55-B5] affects the expression of ECI2 mRNA CTD PMID:20371263 NCBI chr17:30,556,926...30,573,324
Ensembl chr17:30,556,884...30,639,040
JBrowse link
G Egf epidermal growth factor multiple interactions ISO Sulindac inhibits the reaction [EGF protein results in increased phosphorylation of BAD protein]; Sulindac inhibits the reaction [EGF protein results in increased phosphorylation of MAPK1 protein]; Sulindac inhibits the reaction [EGF protein results in increased phosphorylation of MAPK3 protein] CTD PMID:12566304 NCBI chr 2:68,820,616...68,895,537 JBrowse link
G Ehmt2 euchromatic histone lysine methyltransferase 2 decreases expression ISO Sulindac results in decreased expression of EHMT2 mRNA CTD PMID:11906190 NCBI chr20:4,576,033...4,592,980
Ensembl chr20:4,576,057...4,592,980
JBrowse link
G Eif5b eukaryotic translation initiation factor 5B increases expression EXP Sulindac results in increased expression of EIF5B mRNA CTD PMID:24136188 NCBI chr 9:44,658,724...44,713,518
Ensembl chr 9:44,681,494...44,713,199
JBrowse link
G Elapor2 endosome-lysosome associated apoptosis and autophagy regulator family member 2 increases expression ISO Sulindac results in increased expression of ELAPOR2 mRNA CTD PMID:11906190 NCBI chr 4:21,563,848...21,757,668
Ensembl chr 4:21,584,369...21,668,570
JBrowse link
G Eloc elongin C increases expression EXP Sulindac results in increased expression of ELOC mRNA CTD PMID:24136188 NCBI chr 5:2,042,991...2,059,357
Ensembl chr 5:2,042,991...2,059,351
JBrowse link
G Endog endonuclease G affects localization ISO Sulindac affects the localization of ENDOG protein CTD PMID:15946692 NCBI chr 3:8,741,833...8,744,414
Ensembl chr 3:8,741,766...8,744,592
JBrowse link
G Ercc5 ERCC excision repair 5, endonuclease decreases expression ISO Sulindac results in decreased expression of ERCC5 mRNA CTD PMID:11906190 NCBI chr 9:50,928,847...50,970,962
Ensembl chr 9:50,925,619...50,970,955
JBrowse link
G Errfi1 ERBB receptor feedback inhibitor 1 decreases expression EXP Sulindac results in decreased expression of ERRFI1 mRNA CTD PMID:24136188 NCBI chr 5:167,951,564...167,966,011
Ensembl chr 5:167,952,728...167,966,009
JBrowse link
G Ess2 ess-2 splicing factor homolog increases expression ISO Sulindac results in increased expression of ESS2 mRNA CTD PMID:11906190 NCBI chr11:87,224,371...87,234,329
Ensembl chr11:87,224,421...87,233,326
JBrowse link
G Etfdh electron transfer flavoprotein dehydrogenase decreases expression EXP Sulindac results in decreased expression of ETFDH mRNA CTD PMID:24136188 NCBI chr 2:178,367,547...178,389,641
Ensembl chr 2:178,367,549...178,389,608
JBrowse link
G Ets1 ETS proto-oncogene 1, transcription factor increases expression ISO Sulindac results in increased expression of ETS1 mRNA CTD PMID:11906190 NCBI chr 8:33,756,634...33,879,625
Ensembl chr 8:33,816,386...33,879,625
JBrowse link
G Exoc3 exocyst complex component 3 decreases expression EXP Sulindac results in decreased expression of EXOC3 mRNA CTD PMID:24136188 NCBI chr 1:31,700,953...31,731,726
Ensembl chr 1:31,700,953...31,731,815
JBrowse link
G Exoc7 exocyst complex component 7 increases expression EXP Sulindac results in increased expression of EXOC7 mRNA CTD PMID:24136188 NCBI chr10:105,242,152...105,259,795
Ensembl chr10:105,242,152...105,259,795
JBrowse link
G Exosc5 exosome component 5 decreases expression EXP Sulindac results in decreased expression of EXOSC5 mRNA CTD PMID:24136188 NCBI chr 1:82,452,104...82,461,607
Ensembl chr 1:82,452,469...82,461,606
JBrowse link
G Exosc7 exosome component 7 decreases expression EXP Sulindac results in decreased expression of EXOSC7 mRNA CTD PMID:24136188 NCBI chr 8:132,204,628...132,229,968
Ensembl chr 8:132,204,604...132,229,969
JBrowse link
G Fam219b family with sequence similarity 219, member B decreases expression EXP Sulindac results in decreased expression of FAM219B mRNA CTD PMID:24136188 NCBI chr 8:62,316,075...62,322,883
Ensembl chr 8:62,317,265...62,322,883
JBrowse link
G Fam241b family with sequence similarity 241 member B increases expression EXP Sulindac results in increased expression of FAM241B mRNA CTD PMID:24136188 NCBI chr20:31,734,297...31,736,115
Ensembl chr20:31,734,183...31,736,212
JBrowse link
G Fbxl4 F-box and leucine-rich repeat protein 4 increases expression EXP Sulindac results in increased expression of FBXL4 mRNA CTD PMID:24136188 NCBI chr 5:36,555,061...36,628,920
Ensembl chr 5:36,555,109...36,629,689
JBrowse link
G Fbxo42 F-box protein 42 increases expression ISO Sulindac results in increased expression of FBXO42 mRNA CTD PMID:11906190 NCBI chr 5:159,670,662...159,729,070
Ensembl chr 5:159,670,662...159,729,064
JBrowse link
G Fbxo6 F-box protein 6 decreases expression EXP Sulindac results in decreased expression of FBXO6 mRNA CTD PMID:24136188 NCBI chr 5:164,956,285...164,962,075
Ensembl chr 5:164,956,280...164,959,851
JBrowse link
G Fhl2 four and a half LIM domains 2 increases expression ISO Sulindac results in increased expression of FHL2 mRNA CTD PMID:11906190 NCBI chr 9:49,920,611...49,994,906
Ensembl chr 9:49,920,854...49,950,093
JBrowse link
G Fkbp1a FKBP prolyl isomerase 1A decreases expression EXP Sulindac results in decreased expression of FKBP1A mRNA CTD PMID:24136188 NCBI chr 3:147,042,944...147,062,725
Ensembl chr 3:147,042,944...147,062,724
JBrowse link
G Fli1 Fli-1 proto-oncogene, ETS transcription factor decreases expression EXP Sulindac results in decreased expression of FLI1 mRNA CTD PMID:24136188 NCBI chr 8:33,541,932...33,661,111
Ensembl chr 8:33,543,258...33,661,049
JBrowse link
G Flnb filamin B increases expression EXP Sulindac results in increased expression of FLNB mRNA CTD PMID:24136188 NCBI chr15:18,750,152...18,883,019
Ensembl chr15:18,750,118...18,883,005
JBrowse link
G Fmo3 flavin containing dimethylaniline monoxygenase 3 affects metabolic processing
increases metabolic processing
multiple interactions
ISO FMO3 gene polymorphism affects the metabolism of Sulindac
FMO3 protein results in increased metabolism of Sulindac
FMO3 gene polymorphism results in decreased metabolism of and results in increased susceptibility to Sulindac
CTD PMID:15623613, PMID:17050781 NCBI chr13:80,837,418...80,856,214
Ensembl chr13:80,837,420...80,862,963
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit decreases expression ISO Sulindac results in decreased expression of FOS protein CTD PMID:15020200 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Fth1 ferritin heavy chain 1 increases expression ISO Sulindac results in increased expression of FTH1 mRNA CTD PMID:11093808 NCBI chr 1:226,030,940...226,033,228
Ensembl chr 1:226,030,938...226,033,228
JBrowse link
G Ftl1 ferritin light chain 1 decreases expression EXP Sulindac results in decreased expression of FTL1 mRNA CTD PMID:24136188 NCBI chr 1:101,448,190...101,450,034
Ensembl chr 1:101,448,346...101,449,829
JBrowse link
G Fxn frataxin increases expression EXP Sulindac results in increased expression of FXN mRNA CTD PMID:24136188 NCBI chr 1:242,123,975...242,152,834
Ensembl chr 1:242,123,975...242,152,834
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression ISO Sulindac results in increased expression of GADD45A mRNA CTD PMID:11906190 NCBI chr 4:97,782,512...97,784,814
Ensembl chr 4:97,782,512...97,784,842
JBrowse link
G Gal galanin and GMAP prepropeptide affects expression ISO Sulindac affects the expression of GAL protein CTD PMID:12388792 NCBI chr 1:218,653,059...218,657,922
Ensembl chr 1:218,652,917...218,657,925
JBrowse link
G Galk1 galactokinase 1 increases expression EXP Sulindac results in increased expression of GALK1 mRNA CTD PMID:24136188 NCBI chr10:104,560,322...104,564,499
Ensembl chr10:104,560,303...104,564,480
JBrowse link
G Gap43 growth associated protein 43 affects expression ISO Sulindac affects the expression of GAP43 protein CTD PMID:12388792 NCBI chr11:58,624,198...58,717,916
Ensembl chr11:58,624,198...58,717,914
JBrowse link
G Gatad1 GATA zinc finger domain containing 1 increases expression EXP Sulindac results in increased expression of GATAD1 mRNA CTD PMID:24136188 NCBI chr 4:27,647,005...27,658,533
Ensembl chr 4:27,647,335...27,657,167
JBrowse link
G Gatad2a GATA zinc finger domain containing 2A increases expression EXP Sulindac results in increased expression of GATAD2A mRNA CTD PMID:24136188 NCBI chr16:21,177,793...21,267,768
Ensembl chr16:21,178,138...21,268,504
JBrowse link
G Gatd3a glutamine amidotransferase like class 1 domain containing 3A decreases expression ISO Sulindac results in decreased expression of GATD3A mRNA CTD PMID:11906190 NCBI chr20:11,244,353...11,252,450
Ensembl chr20:11,244,353...11,252,449
JBrowse link
G Gba glucosylceramidase beta multiple interactions ISO Sulindac inhibits the reaction [CDKN1A protein results in increased expression of GBA mRNA] CTD PMID:15190207 NCBI chr 2:188,511,781...188,522,602
Ensembl chr 2:188,516,582...188,522,601
JBrowse link
G Gcdh glutaryl-CoA dehydrogenase multiple interactions EXP [Sulindac co-treated with lipopolysaccharide, E coli O55-B5] affects the expression of GCDH mRNA CTD PMID:20371263 NCBI chr19:26,000,497...26,006,970
Ensembl chr19:26,000,497...26,006,970
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit multiple interactions
increases expression
affects expression
ISO Acetylcysteine inhibits the reaction [Sulindac results in increased expression of GCLC protein]
Sulindac affects the expression of GCLC mRNA
CTD PMID:11820781, PMID:15946948 NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468
JBrowse link
G Gcnt1 glucosaminyl (N-acetyl) transferase 1 increases expression ISO Sulindac results in increased expression of GCNT1 mRNA CTD PMID:11093808 NCBI chr 1:236,547,729...236,585,037
Ensembl chr 1:236,580,034...236,585,035
JBrowse link
G Gdf15 growth differentiation factor 15 increases expression ISO Sulindac results in increased expression of GDF15 mRNA; Sulindac results in increased expression of GDF15 protein CTD PMID:11906190, PMID:11984525, PMID:15180942 NCBI chr16:20,555,395...20,557,978
Ensembl chr16:20,555,395...20,557,978
JBrowse link
G Ghitm growth hormone inducible transmembrane protein increases expression EXP Sulindac results in increased expression of GHITM mRNA CTD PMID:24136188 NCBI chr16:14,370,269...14,382,647
Ensembl chr16:14,371,531...14,382,641
JBrowse link
G Ghr growth hormone receptor multiple interactions EXP [Sulindac co-treated with lipopolysaccharide, E coli O55-B5] affects the expression of GHR mRNA CTD PMID:20371263 NCBI chr 2:53,149,225...53,413,954
Ensembl chr 2:53,150,370...53,413,638
JBrowse link
G Glo1 glyoxalase 1 decreases activity ISO Sulindac results in decreased activity of GLO1 protein CTD PMID:17243824 NCBI chr20:9,273,589...9,291,608
Ensembl chr20:9,273,594...9,291,610
JBrowse link
G Gnas GNAS complex locus increases expression EXP Sulindac results in increased expression of GNAS mRNA CTD PMID:24136188 NCBI chr 3:172,374,957...172,434,988
Ensembl chr 3:172,374,957...172,428,483
Ensembl chr 3:172,374,957...172,428,483
JBrowse link
G Gnl3l G protein nucleolar 3 like decreases expression EXP Sulindac results in decreased expression of GNL3L mRNA CTD PMID:24136188 NCBI chr  X:20,037,558...20,070,505
Ensembl chr  X:20,034,882...20,070,578
JBrowse link
G Gnmt glycine N-methyltransferase decreases expression EXP Sulindac results in decreased expression of GNMT mRNA CTD PMID:24136188 NCBI chr 9:16,565,274...16,568,626
Ensembl chr 9:16,565,225...16,568,627
JBrowse link
G Gpx3 glutathione peroxidase 3 multiple interactions EXP [Sulindac co-treated with lipopolysaccharide, E coli O55-B5] affects the expression of GPX3 mRNA CTD PMID:20371263 NCBI chr10:40,247,436...40,255,423
Ensembl chr10:40,247,436...40,255,422
JBrowse link
G Grb10 growth factor receptor bound protein 10 increases expression ISO Sulindac results in increased expression of GRB10 mRNA CTD PMID:11906190 NCBI chr14:92,021,851...92,122,249
Ensembl chr14:92,021,851...92,117,923
JBrowse link
G Grb2 growth factor receptor bound protein 2 increases expression EXP Sulindac results in increased expression of GRB2 mRNA CTD PMID:24136188 NCBI chr10:104,193,953...104,263,071
Ensembl chr10:104,193,955...104,263,071
JBrowse link
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 affects expression EXP Sulindac affects the expression of GRIN1 protein CTD PMID:15123337 NCBI chr 3:2,507,745...2,534,664
Ensembl chr 3:2,506,896...2,534,663
JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B affects expression EXP Sulindac affects the expression of GRIN2B protein CTD PMID:15123337 NCBI chr 4:169,541,620...170,000,216
Ensembl chr 4:169,560,387...169,999,873
JBrowse link
G Grk6 G protein-coupled receptor kinase 6 decreases expression EXP Sulindac results in decreased expression of GRK6 mRNA CTD PMID:24136188 NCBI chr17:9,705,917...9,721,921
Ensembl chr17:9,703,453...9,721,574
JBrowse link
G Grn granulin precursor multiple interactions ISO Sulindac inhibits the reaction [CDKN1A protein results in increased expression of GRN mRNA] CTD PMID:15190207 NCBI chr10:90,377,103...90,383,207
Ensembl chr10:90,376,933...90,383,205
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta decreases phosphorylation ISO Sulindac results in decreased phosphorylation of GSK3B protein CTD PMID:11593435 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268
JBrowse link
G Gstm2 glutathione S-transferase mu 2 multiple interactions EXP [Sulindac co-treated with lipopolysaccharide, E coli O55-B5] affects the expression of GSTM2 mRNA CTD PMID:20371263 NCBI chr 2:210,778,041...210,782,807
Ensembl chr 2:210,720,704...210,782,856
JBrowse link
G Gstt1 glutathione S-transferase theta 1 increases expression EXP Sulindac results in increased expression of GSTT1 protein CTD PMID:9729437 NCBI chr20:13,799,102...13,816,527
Ensembl chr20:13,799,102...13,816,526
JBrowse link
G Gtf2b general transcription factor IIB increases expression
decreases expression
ISO
EXP
Sulindac results in increased expression of GTF2B mRNA
Sulindac results in decreased expression of GTF2B mRNA
CTD PMID:11906190, PMID:24136188 NCBI chr 2:248,709,433...248,727,741
Ensembl chr 2:248,715,281...248,727,741
JBrowse link
G H2ax H2A.X variant histone multiple interactions ISO [Arsenic Trioxide co-treated with Sulindac] results in increased phosphorylation of H2AX protein CTD PMID:18636201 NCBI chr 8:48,665,652...48,666,981
Ensembl chr 8:48,665,652...48,666,981
JBrowse link
G H2az1 H2A.Z variant histone 1 increases expression EXP Sulindac results in increased expression of H2AZ1 mRNA CTD PMID:24136188 NCBI chr 2:243,105,224...243,107,333
Ensembl chr 2:243,105,674...243,106,956
JBrowse link
G Hadhb hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta decreases expression EXP Sulindac results in decreased expression of HADHB mRNA CTD PMID:24136188 NCBI chr 6:27,555,408...27,589,539
Ensembl chr 6:27,555,412...27,582,995
JBrowse link
G Helz2 helicase with zinc finger 2 decreases expression EXP Sulindac results in decreased expression of HELZ2 mRNA CTD PMID:24136188 NCBI chr 3:176,730,024...176,744,382
Ensembl chr 3:176,731,769...176,744,377
JBrowse link
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 increases expression ISO Sulindac results in increased expression of HERPUD1 mRNA CTD PMID:11093808 NCBI chr19:11,046,905...11,057,440
Ensembl chr19:11,046,909...11,057,254
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha multiple interactions
decreases expression
ISO [AKT1 protein affects the reaction [Sulindac analog results in decreased expression of HIF1A protein]] which affects the susceptibility to Oxygen; AKT1 protein affects the reaction [Sulindac analog results in decreased expression of HIF1A protein]
Sulindac analog results in decreased expression of HIF1A mRNA; Sulindac analog results in decreased expression of HIF1A protein
CTD PMID:18924134 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Higd1a HIG1 hypoxia inducible domain family, member 1A increases expression EXP Sulindac results in increased expression of HIGD1A mRNA CTD PMID:24136188 NCBI chr 8:130,482,492...130,491,888
Ensembl chr 8:130,482,493...130,491,998
JBrowse link
G Hlcs holocarboxylase synthetase decreases expression ISO Sulindac results in decreased expression of HLCS mRNA CTD PMID:11906190 NCBI chr11:34,357,372...34,537,798
Ensembl chr11:34,352,287...34,526,931
JBrowse link
G Hmgb3 high mobility group box 3 increases expression EXP Sulindac results in increased expression of HMGB3 mRNA CTD PMID:24136188 NCBI chr17:36,690,190...36,694,329
Ensembl chr17:36,690,249...36,694,325
Ensembl chr14:36,690,249...36,694,325
JBrowse link
G Hmmr hyaluronan-mediated motility receptor decreases expression ISO Sulindac results in decreased expression of HMMR mRNA CTD PMID:11906190 NCBI chr10:25,861,490...25,890,639
Ensembl chr10:25,861,490...25,890,639
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
decreases expression
ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Sulindac promotes the reaction [arsenic trioxide results in increased expression of HMOX1 protein]]; pyrazolanthrone inhibits the reaction [Sulindac promotes the reaction [arsenic trioxide results in increased expression of HMOX1 protein]]; SB 203580 inhibits the reaction [Sulindac promotes the reaction [arsenic trioxide results in increased expression of HMOX1 protein]]; Sulindac promotes the reaction [arsenic trioxide results in increased expression of HMOX1 protein]
Sulindac results in decreased expression of HMOX1 protein
CTD PMID:18636201 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hnf4a hepatocyte nuclear factor 4, alpha multiple interactions EXP [Sulindac co-treated with lipopolysaccharide, E coli O55-B5] affects the expression of HNF4A mRNA CTD PMID:20371263 NCBI chr 3:159,902,441...159,965,003
Ensembl chr 3:159,902,441...159,965,003
JBrowse link
G Hsd17b4 hydroxysteroid (17-beta) dehydrogenase 4 multiple interactions EXP [Sulindac co-treated with lipopolysaccharide, E coli O55-B5] affects the expression of HSD17B4 mRNA CTD PMID:20371263 NCBI chr18:44,810,462...44,897,677
Ensembl chr18:44,810,388...44,897,640
JBrowse link
G Hsf1 heat shock transcription factor 1 increases activity ISO Sulindac results in increased activity of HSF1 protein CTD PMID:10328874 NCBI chr 7:117,538,523...117,565,478
Ensembl chr 7:117,538,523...117,565,478
JBrowse link
G Hspa9 heat shock protein family A (Hsp70) member 9 increases expression EXP Sulindac results in increased expression of HSPA9 mRNA CTD PMID:24136188 NCBI chr18:27,731,072...27,749,235
Ensembl chr18:27,731,072...27,749,235
JBrowse link
G Icam1 intercellular adhesion molecule 1 decreases expression ISO Sulindac results in decreased expression of ICAM1 protein CTD PMID:18059344 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Ifi27 interferon, alpha-inducible protein 27 decreases expression EXP Sulindac results in decreased expression of IFI27 mRNA CTD PMID:24136188 NCBI chr 6:127,327,959...127,334,430
Ensembl chr 6:127,327,959...127,334,428
JBrowse link
G Ifitm3 interferon induced transmembrane protein 3 decreases expression EXP Sulindac results in decreased expression of IFITM3 mRNA CTD PMID:24136188 NCBI chr 1:213,810,712...213,811,821
Ensembl chr 1:213,810,696...213,811,901
JBrowse link
G Ifnar1 interferon alpha and beta receptor subunit 1 decreases expression EXP Sulindac results in decreased expression of IFNAR1 mRNA CTD PMID:24136188 NCBI chr11:31,640,407...31,666,839
Ensembl chr11:31,640,407...31,664,061
JBrowse link
G Ifng interferon gamma multiple interactions ISO Sulindac inhibits the reaction [IFNG protein results in increased expression of CXCL9 mRNA] CTD PMID:17010317 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Iftap intraflagellar transport associated protein increases expression EXP Sulindac results in increased expression of IFTAP mRNA CTD PMID:24136188 NCBI chr 3:91,086,186...91,195,981
Ensembl chr 3:91,086,186...91,195,981
JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta decreases activity ISO Sulindac results in decreased activity of IKBKB protein CTD PMID:19526344 NCBI chr16:74,177,233...74,230,809
Ensembl chr16:74,177,215...74,230,815
JBrowse link
G Il11ra1 interleukin 11 receptor subunit alpha 1 increases expression EXP Sulindac results in increased expression of IL11RA1 mRNA CTD PMID:24136188 NCBI chr 5:58,149,150...58,159,072
Ensembl chr 5:58,151,985...58,159,072
JBrowse link
G Il1a interleukin 1 alpha multiple interactions EXP [Sulindac co-treated with lipopolysaccharide, E coli O55-B5] affects the expression of IL1A mRNA CTD PMID:20371263 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il1b interleukin 1 beta multiple interactions
increases expression
decreases expression
ISO
EXP
[Sulindac co-treated with epigallocatechin gallate] results in decreased expression of IL1B mRNA; Sulindac inhibits the reaction [IL1B protein results in increased abundance of Hyaluronic Acid]; Sulindac inhibits the reaction [IL1B protein results in increased expression of CCL5 mRNA]
Sulindac results in increased expression of IL1B
Sulindac results in decreased expression of IL1B protein
Sulindac results in decreased expression of IL1B mRNA
CTD PMID:10328874, PMID:11318944, PMID:12628509, PMID:15123337, PMID:16159934, PMID:24136188 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il24 interleukin 24 multiple interactions
increases expression
ISO Sulindac promotes the reaction [IL24 protein results in increased phosphorylation of MAPK8 protein]
[Sulindac results in increased expression of IL24 protein] which results in increased expression of CASP3 protein; [Sulindac results in increased expression of IL24 protein] which results in increased expression of CASP9 protein; Sulindac results in increased expression of IL24 protein
CTD PMID:15713900 NCBI chr13:47,618,451...47,623,849
Ensembl chr13:47,618,452...47,623,849
JBrowse link
G Il6 interleukin 6 multiple interactions
increases expression
EXP [Sulindac co-treated with lipopolysaccharide, E coli O55-B5] affects the expression of IL6 mRNA
Sulindac results in increased expression of IL6
CTD PMID:20371263, PMID:24136188 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Ilk integrin-linked kinase decreases activity ISO Sulindac results in decreased activity of ILK protein CTD PMID:11593435 NCBI chr 1:170,578,941...170,585,192
Ensembl chr 1:170,578,889...170,585,189
JBrowse link
G Inpp5e inositol polyphosphate-5-phosphatase E increases expression ISO Sulindac results in increased expression of INPP5E mRNA CTD PMID:11906190 NCBI chr 3:3,843,307...3,856,154
Ensembl chr 3:3,843,307...3,855,981
JBrowse link
G Ipmk inositol polyphosphate multikinase decreases expression EXP Sulindac results in decreased expression of IPMK mRNA CTD PMID:24136188 NCBI chr20:18,457,309...18,489,884
Ensembl chr20:18,457,310...18,489,833
JBrowse link
G Irak2 interleukin-1 receptor-associated kinase 2 multiple interactions EXP [Sulindac co-treated with lipopolysaccharide, E coli O55-B5] affects the expression of IRAK2 mRNA CTD PMID:20371263 NCBI chr 4:145,594,575...145,651,066
Ensembl chr 4:145,594,575...145,651,053
JBrowse link
G Irf7 interferon regulatory factor 7 decreases expression EXP Sulindac results in decreased expression of IRF7 mRNA CTD PMID:24136188 NCBI chr 1:214,249,388...214,252,909
Ensembl chr 1:214,248,837...214,252,456
JBrowse link
G Isca1 iron-sulfur cluster assembly 1 decreases expression EXP Sulindac results in decreased expression of ISCA1 mRNA CTD PMID:24136188 NCBI chr17:5,281,727...5,294,386
Ensembl chr17:5,281,727...5,294,384
JBrowse link
G Itga2 integrin subunit alpha 2 increases expression ISO Sulindac results in increased expression of ITGA2 mRNA CTD PMID:11906190 NCBI chr 2:46,996,904...47,097,011
Ensembl chr 2:47,000,323...47,096,961
JBrowse link
G Itgb3 integrin subunit beta 3 multiple interactions ISO Sulindac inhibits the reaction [CDKN1A protein results in increased expression of ITGB3 mRNA] CTD PMID:15190207 NCBI chr10:92,667,869...92,783,413
Ensembl chr10:92,667,869...92,783,410
JBrowse link
G Itgb4 integrin subunit beta 4 multiple interactions ISO [Sulindac co-treated with epigallocatechin gallate] results in decreased expression of ITGB4 mRNA CTD PMID:12628509 NCBI chr10:104,524,000...104,560,180
Ensembl chr10:104,523,996...104,561,078
JBrowse link
G Jkamp JNK1/MAPK8-associated membrane protein decreases expression EXP Sulindac results in decreased expression of JKAMP mRNA CTD PMID:24136188 NCBI chr 6:94,835,845...94,849,784
Ensembl chr 6:94,835,845...94,849,784
JBrowse link
G Josd1 Josephin domain containing 1 decreases expression EXP Sulindac results in decreased expression of JOSD1 mRNA CTD PMID:24136188 NCBI chr 7:120,905,343...120,919,261
Ensembl chr 7:120,905,337...120,919,261
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit decreases expression
multiple interactions
ISO Sulindac results in decreased expression of JUN protein
[Sulindac co-treated with Plant Extracts] results in decreased expression of JUN protein
CTD PMID:12351151, PMID:12584176 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Jund JunD proto-oncogene, AP-1 transcription factor subunit increases expression ISO Sulindac results in increased expression of JUND mRNA CTD PMID:11906190 NCBI chr16:20,485,028...20,486,707
Ensembl chr16:20,485,029...20,486,707
JBrowse link
G Kcnh3 potassium voltage-gated channel subfamily H member 3 decreases expression EXP Sulindac results in decreased expression of KCNH3 mRNA CTD PMID:24136188 NCBI chr 7:140,788,987...140,910,426
Ensembl chr 7:140,788,987...140,910,422
JBrowse link
G Kctd5 potassium channel tetramerization domain containing 5 increases expression EXP Sulindac results in increased expression of KCTD5 mRNA CTD PMID:24136188 NCBI chr10:13,420,152...13,446,323
Ensembl chr10:13,420,154...13,446,135
JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 decreases expression EXP Sulindac results in decreased expression of KEAP1 mRNA CTD PMID:24136188 NCBI chr 8:22,250,518...22,259,868
Ensembl chr 8:22,250,518...22,259,779
JBrowse link
G Khsrp KH-type splicing regulatory protein increases expression EXP Sulindac results in increased expression of KHSRP mRNA CTD PMID:24136188 NCBI chr 9:10,013,795...10,023,670
Ensembl chr 9:10,013,854...10,022,924
JBrowse link
G Kif14 kinesin family member 14 increases expression ISO Sulindac results in increased expression of KIF14 mRNA CTD PMID:11906190 NCBI chr13:53,350,073...53,421,992
Ensembl chr13:53,351,717...53,420,111
JBrowse link
G Klf5 Kruppel-like factor 5 increases expression ISO Sulindac results in increased expression of KLF5 mRNA CTD PMID:11906190 NCBI chr15:83,703,796...83,722,921
Ensembl chr15:83,703,791...83,722,921
JBrowse link
G Kras KRAS proto-oncogene, GTPase affects response to substance ISO KRAS protein affects the susceptibility to Sulindac CTD PMID:11751493 NCBI chr 4:179,482,562...179,515,483
Ensembl chr 4:179,486,105...179,515,558
JBrowse link
G Lad1 ladinin 1 increases expression ISO Sulindac results in increased expression of LAD1 mRNA CTD PMID:11507085 NCBI chr13:52,645,257...52,659,619
Ensembl chr13:52,645,257...52,659,619
JBrowse link
G Lamtor4 late endosomal/lysosomal adaptor, MAPK and MTOR activator 4 decreases expression EXP Sulindac results in decreased expression of LAMTOR4 mRNA CTD PMID:24136188 NCBI chr12:19,573,909...19,577,625
Ensembl chr12:19,573,909...19,577,624
JBrowse link
G Larp1b La ribonucleoprotein 1B decreases expression EXP Sulindac results in decreased expression of LARP1B mRNA CTD PMID:24136188 NCBI chr 2:127,845,034...127,876,793
Ensembl chr 2:127,845,034...127,876,793
JBrowse link
G Larp4 La ribonucleoprotein 4 increases expression ISO Sulindac results in increased expression of LARP4 mRNA CTD PMID:11906190 NCBI chr 7:141,630,229...141,676,242 JBrowse link
G Lbp lipopolysaccharide binding protein multiple interactions EXP [Sulindac co-treated with lipopolysaccharide, E coli O55-B5] affects the expression of LBP mRNA CTD PMID:20371263 NCBI chr 3:154,786,232...154,812,910
Ensembl chr 3:154,786,215...154,813,464
JBrowse link
G Ldb1 LIM domain binding 1 increases expression ISO Sulindac results in increased expression of LDB1 mRNA CTD PMID:11906190 NCBI chr 1:265,772,729...265,798,442
Ensembl chr 1:265,785,409...265,798,167
JBrowse link
G Lef1 lymphoid enhancer binding factor 1 multiple interactions ISO Sulindac results in decreased activity of [LEF1 protein binds to CTNNB1 protein] CTD PMID:11751639 NCBI chr 2:236,232,115...236,345,061
Ensembl chr 2:236,233,239...236,345,056
JBrowse link
G Lfng LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase increases expression ISO Sulindac results in increased expression of LFNG mRNA CTD PMID:11906190 NCBI chr12:16,117,767...16,126,211
Ensembl chr12:16,118,634...16,126,953
JBrowse link
G Lgals3 galectin 3 multiple interactions ISO Sulindac inhibits the reaction [CDKN1A protein results in increased expression of LGALS3 mRNA] CTD PMID:15190207 NCBI chr15:24,153,602...24,165,537
Ensembl chr15:24,141,651...24,165,537
JBrowse link
G Lgals3bp galectin 3 binding protein multiple interactions ISO Sulindac inhibits the reaction [CDKN1A protein results in increased expression of LGALS3BP mRNA] CTD PMID:15190207 NCBI chr10:107,415,334...107,424,672
Ensembl chr10:107,415,326...107,424,710
JBrowse link
G Lipe lipase E, hormone sensitive type decreases expression EXP Sulindac results in decreased expression of LIPE mRNA CTD PMID:24136188 NCBI chr 1:82,248,031...82,266,727
Ensembl chr 1:82,248,046...82,266,727
JBrowse link
G Litaf lipopolysaccharide-induced TNF factor increases expression EXP Sulindac results in increased expression of LITAF mRNA CTD PMID:24136188 NCBI chr10:4,753,546...4,763,272
Ensembl chr10:4,719,713...4,763,510
JBrowse link
G Lmf2 lipase maturation factor 2 decreases expression EXP Sulindac results in decreased expression of LMF2 mRNA CTD PMID:24136188 NCBI chr 7:130,322,018...130,326,470
Ensembl chr 7:130,322,020...130,326,470
JBrowse link
G LOC100912290 histone H4-like increases expression ISO Sulindac results in increased expression of H4C15 mRNA CTD PMID:11906190 NCBI chr 4:170,092,457...170,117,607 JBrowse link
G Lonp1 lon peptidase 1, mitochondrial decreases expression EXP Sulindac results in decreased expression of LONP1 mRNA CTD PMID:24136188 NCBI chr 9:10,428,853...10,441,180
Ensembl chr 9:10,428,853...10,441,177
JBrowse link
G Lox lysyl oxidase decreases expression ISO Sulindac analog results in decreased expression of LOX mRNA CTD PMID:18924134 NCBI chr18:47,500,320...47,577,819
Ensembl chr18:47,500,330...47,577,819
JBrowse link
G Lrpprc leucine-rich pentatricopeptide repeat containing decreases expression EXP Sulindac results in decreased expression of LRPPRC mRNA CTD PMID:24136188 NCBI chr 6:7,984,043...8,066,874
Ensembl chr 6:7,984,019...8,066,868
JBrowse link
G Lsm10 LSM10, U7 small nuclear RNA associated increases expression EXP Sulindac results in increased expression of LSM10 mRNA CTD PMID:24136188 NCBI chr 5:144,106,339...144,108,703
Ensembl chr 5:144,106,802...144,108,708
JBrowse link
G Lsm12 LSM12 homolog increases expression EXP Sulindac results in increased expression of LSM12 mRNA CTD PMID:24136188 NCBI chr10:90,105,562...90,127,600
Ensembl chr10:90,105,562...90,127,600
JBrowse link
G Lsm6 LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated increases expression EXP Sulindac results in increased expression of LSM6 mRNA CTD PMID:24136188 NCBI chr19:32,770,640...32,785,215
Ensembl chr19:32,770,655...32,785,215
JBrowse link
G Macroh2a1 macroH2A.1 histone decreases expression EXP Sulindac results in decreased expression of MACROH2A1 mRNA CTD PMID:24136188 NCBI chr17:9,282,109...9,344,698
Ensembl chr17:9,282,675...9,344,678
JBrowse link
G Maoa monoamine oxidase A decreases expression EXP Sulindac results in decreased expression of MAOA mRNA CTD PMID:24136188 NCBI chr  X:6,554,698...6,620,722
Ensembl chr  X:6,554,698...6,620,722
JBrowse link
G Maob monoamine oxidase B multiple interactions EXP [Sulindac co-treated with lipopolysaccharide, E coli O55-B5] affects the expression of MAOB mRNA CTD PMID:20371263 NCBI chr  X:6,430,694...6,533,520
Ensembl chr  X:6,430,594...6,533,534
JBrowse link
G Map3k8 mitogen-activated protein kinase kinase kinase 8 multiple interactions EXP [Sulindac co-treated with lipopolysaccharide, E coli O55-B5] affects the expression of MAP3K8 mRNA CTD PMID:20371263 NCBI chr17:56,109,403...56,129,925
Ensembl chr17:56,109,549...56,129,919
JBrowse link
G Map4k3 mitogen-activated protein kinase kinase kinase kinase 3 increases expression ISO Sulindac results in increased expression of MAP4K3 mRNA CTD PMID:11906190 NCBI chr 6:3,276,732...3,444,519
Ensembl chr 6:3,276,738...3,444,519
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases phosphorylation
ISO
EXP
[Sulindac co-treated with Arsenic Trioxide] results in increased phosphorylation of MAPK1 protein; Arsenic Trioxide promotes the reaction [Sulindac results in increased phosphorylation of MAPK1 protein]; Sulindac inhibits the reaction [EGF protein results in increased phosphorylation of MAPK1 protein]; Sulindac promotes the reaction [Arsenic Trioxide results in increased phosphorylation of MAPK1 protein]
[Sulindac co-treated with lipopolysaccharide, E coli O55-B5] affects the expression of MAPK1 mRNA
CTD PMID:12566304, PMID:18281123, PMID:18636201, PMID:20371263 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases phosphorylation
ISO [Sulindac co-treated with Arsenic Trioxide] results in increased phosphorylation of MAPK3 protein; Arsenic Trioxide promotes the reaction [Sulindac results in increased phosphorylation of MAPK3 protein]; Sulindac inhibits the reaction [EGF protein results in increased phosphorylation of MAPK3 protein]; Sulindac promotes the reaction [Arsenic Trioxide results in increased phosphorylation of MAPK3 protein] CTD PMID:12566304, PMID:18281123, PMID:18636201 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions
increases phosphorylation
increases expression
ISO CDKN1A protein promotes the reaction [Sulindac results in increased expression of and results in increased phosphorylation of MAPK8 protein]; MAPK8 affects the reaction [[Sulindac co-treated with Arsenic Trioxide] results in increased phosphorylation of BCL2L1 protein]; Sulindac promotes the reaction [IL24 protein results in increased phosphorylation of MAPK8 protein]; Sulindac results in increased expression of and results in increased phosphorylation of MAPK8 protein; Sulindac results in increased phosphorylation of and results in increased activity of MAPK8 protein
Sulindac results in increased phosphorylation of MAPK8 protein
Sulindac results in increased expression of MAPK8 mRNA
CTD PMID:15713900, PMID:17292881, PMID:18281123 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
JBrowse link
G Mark3 microtubule affinity regulating kinase 3 decreases expression EXP Sulindac results in decreased expression of MARK3 mRNA CTD PMID:24136188 NCBI chr 6:136,040,957...136,129,780
Ensembl chr 6:136,041,777...136,129,661
JBrowse link
G Mbd2 methyl-CpG binding domain protein 2 decreases expression EXP Sulindac results in decreased expression of MBD2 mRNA CTD PMID:24136188 NCBI chr18:65,814,026...65,885,115
Ensembl chr18:65,814,026...65,885,114
JBrowse link
G Mbd3 methyl-CpG binding domain protein 3 decreases expression EXP Sulindac results in decreased expression of MBD3 mRNA CTD PMID:24136188 NCBI chr 7:12,179,046...12,186,251
Ensembl chr 7:12,179,203...12,186,656
JBrowse link
G Me1 malic enzyme 1 multiple interactions EXP [Sulindac co-treated with lipopolysaccharide, E coli O55-B5] affects the expression of ME1 mRNA CTD PMID:20371263 NCBI chr 8:94,256,830...94,368,834
Ensembl chr 8:94,256,839...94,368,834
JBrowse link
G Med10 mediator complex subunit 10 increases expression EXP Sulindac results in increased expression of MED10 mRNA CTD PMID:24136188 NCBI chr 1:36,107,249...36,118,887
Ensembl chr 1:36,107,232...36,112,993
JBrowse link
G Med15 mediator complex subunit 15 increases expression ISO Sulindac results in increased expression of MED15 mRNA CTD PMID:11906190 NCBI chr11:87,553,868...87,628,631
Ensembl chr11:87,553,868...87,628,502
JBrowse link
G Mesd mesoderm development LRP chaperone decreases expression EXP Sulindac results in decreased expression of MESD mRNA CTD PMID:24136188 NCBI chr 1:146,030,211...146,043,097
Ensembl chr 1:146,037,426...146,043,097
JBrowse link
G Mettl23 methyltransferase like 23 increases expression EXP Sulindac results in increased expression of METTL23 mRNA CTD PMID:24136188 NCBI chr10:105,787,935...105,793,307
Ensembl chr10:105,787,935...105,792,598
JBrowse link
G Mfap3 microfibril associated protein 3 decreases expression EXP Sulindac results in decreased expression of MFAP3 mRNA CTD PMID:24136188 NCBI chr10:42,933,077...42,945,591
Ensembl chr10:42,933,077...42,945,564
JBrowse link
G Mff mitochondrial fission factor decreases expression EXP Sulindac results in decreased expression of MFF mRNA CTD PMID:24136188 NCBI chr 9:88,490,280...88,518,517
Ensembl chr 9:88,493,593...88,517,827
JBrowse link
G Mgst2 microsomal glutathione S-transferase 2 multiple interactions EXP [Sulindac co-treated with lipopolysaccharide, E coli O55-B5] affects the expression of MGST2 mRNA CTD PMID:20371263 NCBI chr 2:140,708,396...140,727,381
Ensembl chr 2:140,708,397...140,727,281
JBrowse link
G Mgst3 microsomal glutathione S-transferase 3 multiple interactions EXP [Sulindac co-treated with lipopolysaccharide, E coli O55-B5] affects the expression of MGST3 mRNA CTD PMID:20371263 NCBI chr13:85,601,499...85,622,392
Ensembl chr13:85,601,499...85,622,314
JBrowse link
G Miip migration and invasion inhibitory protein increases expression ISO Sulindac results in increased expression of MIIP mRNA CTD PMID:11906190 NCBI chr 5:164,672,464...164,679,503
Ensembl chr 5:164,672,471...164,679,654
JBrowse link
G Mllt6 MLLT6, PHD finger containing decreases expression EXP Sulindac results in decreased expression of MLLT6 mRNA CTD PMID:24136188 NCBI chr10:85,607,988...85,628,171
Ensembl chr10:85,608,544...85,625,854
JBrowse link
G Mmp14 matrix metallopeptidase 14 decreases expression EXP Sulindac results in decreased expression of MMP14 mRNA CTD PMID:24136188 NCBI chr15:33,074,441...33,083,666
Ensembl chr15:33,074,441...33,083,655
JBrowse link
G Mmp7 matrix metallopeptidase 7 decreases expression ISO Sulindac results in decreased expression of MMP7 mRNA; Sulindac results in decreased expression of MMP7 protein CTD PMID:18499699 NCBI chr 8:5,893,253...5,900,965
Ensembl chr 8:5,893,249...5,901,049
JBrowse link
G Mogs mannosyl-oligosaccharide glucosidase decreases expression EXP Sulindac results in decreased expression of MOGS mRNA CTD PMID:24136188 NCBI chr 4:113,948,328...113,951,731
Ensembl chr 4:113,948,514...113,951,847
JBrowse link
G Mrpl1 mitochondrial ribosomal protein L1 decreases expression EXP Sulindac results in decreased expression of MRPL1 mRNA CTD PMID:24136188 NCBI chr14:14,951,507...15,008,136
Ensembl chr14:14,951,495...15,008,150
JBrowse link
G mrpl11 mitochondrial ribosomal protein L11 decreases expression EXP Sulindac results in decreased expression of MRPL11 mRNA CTD PMID:24136188 NCBI chr 1:220,243,469...220,246,340
Ensembl chr 1:220,243,473...220,246,346
JBrowse link
G Mrpl13 mitochondrial ribosomal protein L13 increases expression EXP Sulindac results in increased expression of MRPL13 mRNA CTD PMID:24136188 NCBI chr 7:95,288,400...95,309,997
Ensembl chr 7:95,288,376...95,310,005
JBrowse link
G Mrpl17 mitochondrial ribosomal protein L17 decreases expression EXP Sulindac results in decreased expression of MRPL17 mRNA CTD PMID:24136188 NCBI chr 1:170,652,293...170,653,982
Ensembl chr 1:170,652,294...170,653,920
JBrowse link
G Mrpl20 mitochondrial ribosomal protein L20 decreases expression EXP Sulindac results in decreased expression of MRPL20 mRNA CTD PMID:24136188 NCBI chr 5:173,248,245...173,252,775
Ensembl chr 5:173,248,245...173,252,775
JBrowse link
G Mrpl22 mitochondrial ribosomal protein L22 increases expression EXP Sulindac results in increased expression of MRPL22 mRNA CTD PMID:24136188 NCBI chr10:43,601,786...43,612,119
Ensembl chr10:43,601,689...43,612,121
JBrowse link
G Mrpl23 mitochondrial ribosomal protein L23 decreases expression EXP Sulindac results in decreased expression of MRPL23 mRNA CTD PMID:24136188 NCBI chr 1:215,701,544...215,709,313
Ensembl chr 1:215,701,544...215,709,313
JBrowse link
G Mrpl32 mitochondrial ribosomal protein L32 increases expression EXP Sulindac results in increased expression of MRPL32 mRNA CTD PMID:24136188 NCBI chr17:53,102,534...53,105,400
Ensembl chr17:53,102,534...53,105,400
JBrowse link
G Mrpl37 mitochondrial ribosomal protein L37 decreases expression EXP Sulindac results in decreased expression of MRPL37 mRNA CTD PMID:24136188 NCBI chr 5:126,656,330...126,666,830
Ensembl chr 5:126,650,502...126,666,833
JBrowse link
G Mrpl53 mitochondrial ribosomal protein L53 increases expression EXP Sulindac results in increased expression of MRPL53 mRNA CTD PMID:24136188 NCBI chr 4:113,942,037...113,942,927
Ensembl chr 4:113,942,041...113,942,674
JBrowse link
G Mrpl54 mitochondrial ribosomal protein L54 increases expression EXP Sulindac results in increased expression of MRPL54 mRNA CTD PMID:24136188 NCBI chr 7:11,321,057...11,323,577
Ensembl chr 7:11,321,057...11,323,577
JBrowse link
G Mrpl58 mitochondrial ribosomal protein L58 decreases expression EXP Sulindac results in decreased expression of MRPL58 mRNA CTD PMID:24136188 NCBI chr10:103,956,019...103,962,515
Ensembl chr10:103,956,019...103,962,515
JBrowse link
G Mrps14 mitochondrial ribosomal protein S14 decreases expression EXP Sulindac results in decreased expression of MRPS14 mRNA CTD PMID:24136188 NCBI chr13:77,940,454...77,946,201
Ensembl chr13:77,940,454...77,946,201
JBrowse link
G Mrps24 mitochondrial ribosomal protein S24 decreases expression EXP Sulindac results in decreased expression of MRPS24 mRNA CTD PMID:24136188 NCBI chr14:85,947,763...85,951,891
Ensembl chr14:85,947,765...85,951,899
JBrowse link
G Mrps31 mitochondrial ribosomal protein S31 decreases expression EXP Sulindac results in decreased expression of MRPS31 mRNA CTD PMID:24136188 NCBI chr16:74,467,874...74,504,834
Ensembl chr16:74,467,851...74,496,731
JBrowse link
G Mrps33 mitochondrial ribosomal protein S33 increases expression EXP Sulindac results in increased expression of MRPS33 mRNA CTD PMID:24136188 NCBI chr 4:67,606,971...67,616,056
Ensembl chr 4:67,607,273...67,610,710
JBrowse link
G Mrps7 mitochondrial ribosomal protein S7 decreases expression EXP Sulindac results in decreased expression of MRPS7 mRNA CTD PMID:24136188 NCBI chr10:104,155,805...104,158,840
Ensembl chr10:104,155,805...104,158,839
JBrowse link
G Mrps9 mitochondrial ribosomal protein S9 increases expression EXP Sulindac results in increased expression of MRPS9 mRNA CTD PMID:24136188 NCBI chr 9:49,647,257...49,704,828
Ensembl chr 9:49,647,257...49,704,828
JBrowse link
G Mthfd2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase increases expression ISO Sulindac results in increased expression of MTHFD2 mRNA CTD PMID:11906190 NCBI chr 4:115,004,433...115,015,965
Ensembl chr 4:115,004,448...115,015,965
JBrowse link
G Mtpn myotrophin increases expression EXP Sulindac results in increased expression of MTPN mRNA CTD PMID:24136188 NCBI chr 4:63,012,009...63,039,422
Ensembl chr 4:63,012,011...63,039,422
JBrowse link
G Mug1 murinoglobulin 1 decreases expression EXP Sulindac results in decreased expression of MUG1 mRNA CTD PMID:24136188 NCBI chr 4:154,676,382...154,729,288
Ensembl chr 4:154,391,647...154,729,310
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor multiple interactions
decreases expression
increases expression
ISO
EXP
CTNNB1 protein affects the reaction [Sulindac results in decreased expression of MYC protein]
Sulindac inhibits the reaction [Azoxymethane results in increased expression of MYC mRNA]; Sulindac inhibits the reaction [Azoxymethane results in increased expression of MYC protein]
Sulindac results in increased expression of MYC mRNA
CTD PMID:12189186, PMID:12414619, PMID:17292881, PMID:18291362 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
JBrowse link
G Mzf1 myeloid zinc finger 1 decreases expression EXP Sulindac results in decreased expression of MZF1 mRNA CTD PMID:24136188 NCBI chr 1:65,520,827...65,533,233
Ensembl chr 1:65,522,118...65,533,212
JBrowse link
G Naa35 N(alpha)-acetyltransferase 35, NatC auxiliary subunit decreases expression EXP Sulindac results in decreased expression of NAA35 mRNA CTD PMID:24136188 NCBI chr17:5,411,479...5,463,898
Ensembl chr17:5,411,506...5,463,898
JBrowse link
G Nampt nicotinamide phosphoribosyltransferase decreases expression EXP Sulindac results in decreased expression of NAMPT mRNA CTD PMID:24136188 NCBI chr 6:52,122,085...52,156,473
Ensembl chr 6:52,122,085...52,156,472
JBrowse link
G Nap1l1 nucleosome assembly protein 1-like 1 decreases expression ISO Sulindac results in decreased expression of NAP1L1 mRNA CTD PMID:11507085 NCBI chr 7:54,213,305...54,237,880
Ensembl chr 7:54,213,319...54,236,625
JBrowse link
G Nat1 N-acetyltransferase 1 decreases expression ISO Sulindac results in decreased expression of NAT1 mRNA CTD PMID:11828994 NCBI chr16:23,970,742...23,991,573
Ensembl chr16:23,970,743...23,991,573
JBrowse link
G Ndrg1 N-myc downstream regulated 1 increases expression
decreases expression
ISO
EXP
Sulindac results in increased expression of NDRG1 mRNA
Sulindac results in decreased expression of NDRG1 mRNA
CTD PMID:16273229, PMID:24136188 NCBI chr 7:107,734,326...107,775,701
Ensembl chr 7:107,734,323...107,775,714
JBrowse link
G Ndst2 N-deacetylase and N-sulfotransferase 2 decreases expression ISO Sulindac results in decreased expression of NDST2 mRNA CTD PMID:11906190 NCBI chr15:3,995,797...4,006,491
Ensembl chr15:3,996,048...4,006,491
JBrowse link
G Ndufa5 NADH:ubiquinone oxidoreductase subunit A5 increases expression EXP Sulindac results in increased expression of NDUFA5 mRNA CTD PMID:24136188 NCBI chr 4:51,590,413...51,598,771
Ensembl chr 4:51,590,413...51,598,771
JBrowse link
G Ndufv3 NADH:ubiquinone oxidoreductase subunit V3 increases expression EXP Sulindac results in increased expression of NDUFV3 mRNA CTD PMID:24136188 NCBI chr20:10,265,826...10,275,298
Ensembl chr20:10,265,806...10,275,304
JBrowse link
G Nek7 NIMA-related kinase 7 decreases expression EXP Sulindac results in decreased expression of NEK7 mRNA CTD PMID:24136188 NCBI chr13:55,485,759...55,617,534
Ensembl chr13:55,488,531...55,561,750
JBrowse link
G Neu1 neuraminidase 1 increases expression ISO Sulindac results in increased expression of NEU1 mRNA CTD PMID:11906190 NCBI chr20:4,610,995...4,615,258
Ensembl chr20:4,610,995...4,615,247
JBrowse link
G Nfe2l1 nuclear factor, erythroid 2-like 1 increases expression ISO
EXP
Sulindac results in increased expression of NFE2L1 mRNA CTD PMID:11906190, PMID:24136188 NCBI chr10:84,686,762...84,699,313
Ensembl chr10:84,682,460...84,698,886
JBrowse link
G Nfib nuclear factor I/B multiple interactions EXP [Sulindac co-treated with lipopolysaccharide, E coli O55-B5] affects the expression of NFIB mRNA CTD PMID:20371263 NCBI chr 5:100,436,343...100,647,962
Ensembl chr 5:100,439,082...100,647,727
JBrowse link
G Nfil3 nuclear factor, interleukin 3 regulated increases expression ISO Sulindac results in increased expression of NFIL3 mRNA CTD PMID:11906190 NCBI chr17:12,261,102...12,276,316
Ensembl chr17:12,261,102...12,276,315
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions
decreases activity
ISO Acetylcysteine inhibits the reaction [Sulindac analog results in decreased activity of NFKB1 protein]; Sulindac inhibits the reaction [TNF protein results in increased activity of [NFKB1 protein binds to RELA protein]]; Sulindac inhibits the reaction [TNF protein results in increased activity of NFKB1 protein] CTD PMID:15489888, PMID:18922898 NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions
decreases phosphorylation
ISO
EXP
[[Sulindac co-treated with arsenic trioxide] results in decreased phosphorylation of and results in decreased degradation of NFKBIA protein] which affects the localization of RELA protein; [Sulindac co-treated with arsenic trioxide] results in decreased phosphorylation of and results in decreased degradation of NFKBIA protein; Sulindac inhibits the reaction [TNF protein results in increased degradation of NFKBIA protein]; Sulindac results in increased degradation of and results in decreased expression of NFKBIA protein
[Sulindac co-treated with lipopolysaccharide, E coli O55-B5] affects the expression of NFKBIA mRNA
Sulindac results in decreased phosphorylation of NFKBIA protein
CTD PMID:11591705, PMID:15489888, PMID:18059344, PMID:18575716, PMID:20371263 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Nfu1 NFU1 iron-sulfur cluster scaffold decreases expression EXP Sulindac results in decreased expression of NFU1 mRNA CTD PMID:24136188 NCBI chr 4:118,814,284...118,834,955
Ensembl chr 4:118,814,284...118,834,955
JBrowse link
G Npc1 NPC intracellular cholesterol transporter 1 increases expression ISO Sulindac results in increased expression of NPC1 mRNA CTD PMID:11906190 NCBI chr18:3,616,878...3,662,656
Ensembl chr18:3,616,878...3,662,683
JBrowse link
G Nphp1 nephrocystin 1 increases expression EXP Sulindac results in increased expression of NPHP1 mRNA CTD PMID:24136188 NCBI chr 3:120,316,048...120,370,089
Ensembl chr 3:120,316,047...120,373,500
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases activity
increases expression
ISO Sulindac results in increased activity of NQO1 protein
Sulindac results in increased expression of NQO1 mRNA
CTD PMID:11093808, PMID:17985343 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Nsmf NMDA receptor synaptonuclear signaling and neuronal migration factor decreases expression EXP Sulindac results in decreased expression of NSMF mRNA CTD PMID:24136188 NCBI chr 3:2,262,173...2,270,996
Ensembl chr 3:2,262,253...2,270,995
JBrowse link
G Nudt16l1 nudix hydrolase 16 like 1 increases expression EXP Sulindac results in increased expression of NUDT16L1 mRNA CTD PMID:24136188 NCBI chr10:10,829,866...10,831,782
Ensembl chr10:10,829,867...10,831,782
JBrowse link
G Numb NUMB, endocytic adaptor protein increases expression EXP Sulindac results in increased expression of NUMB mRNA CTD PMID:24136188 NCBI chr 6:107,279,917...107,325,345
Ensembl chr 6:107,279,920...107,325,345
JBrowse link
G Nup37 nucleoporin 37 increases expression EXP Sulindac results in increased expression of NUP37 mRNA CTD PMID:24136188 NCBI chr 7:28,715,299...28,750,978
Ensembl chr 7:28,701,690...28,743,326
JBrowse link
G Nupr2 nuclear protein 2, transcriptional regulator increases expression EXP Sulindac results in increased expression of NUPR2 mRNA CTD PMID:24136188 NCBI chr12:30,300,936...30,304,041
Ensembl chr12:30,303,725...30,304,036
JBrowse link
G Orc4 origin recognition complex, subunit 4 decreases expression ISO Sulindac results in decreased expression of ORC4 mRNA CTD PMID:11906190 NCBI chr 3:33,034,913...33,075,833
Ensembl chr 3:33,037,034...33,075,685
JBrowse link
G Osbpl9 oxysterol binding protein-like 9 decreases expression EXP Sulindac results in decreased expression of OSBPL9 mRNA CTD PMID:24136188 NCBI chr 5:128,694,407...128,839,435
Ensembl chr 5:128,694,803...128,839,433
JBrowse link
G Ostf1 osteoclast stimulating factor 1 increases expression ISO Sulindac results in increased expression of OSTF1 mRNA CTD PMID:11906190 NCBI chr 1:234,749,568...234,796,739
Ensembl chr 1:234,749,568...234,796,739
JBrowse link
G Ostm1 osteoclastogenesis associated transmembrane protein 1 increases expression EXP Sulindac results in increased expression of OSTM1 mRNA CTD PMID:24136188 NCBI chr20:47,394,979...47,430,304
Ensembl chr20:47,395,014...47,430,284
JBrowse link
G Otud1 OTU deubiquitinase 1 increases expression ISO Sulindac results in increased expression of OTUD1 mRNA CTD PMID:11906190 NCBI chr17:86,406,643...86,410,670
Ensembl chr17:86,408,151...86,409,518
JBrowse link
G Pacsin3 protein kinase C and casein kinase substrate in neurons 3 increases expression EXP Sulindac results in increased expression of PACSIN3 mRNA CTD PMID:24136188 NCBI chr 3:80,072,425...80,081,058
Ensembl chr 3:80,072,489...80,081,047
JBrowse link
G Pak6 p21 (RAC1) activated kinase 6 decreases expression EXP Sulindac results in decreased expression of PAK6 mRNA CTD PMID:24136188 NCBI chr 3:110,442,175...110,486,317
Ensembl chr 3:110,442,637...110,487,526
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions
increases activity
ISO [Sulindac co-treated with arsenic trioxide] results in increased cleavage of PARP1 protein; Acetylcysteine inhibits the reaction [[Sulindac co-treated with arsenic trioxide] results in increased cleavage of PARP1 protein]; pyrazolanthrone inhibits the reaction [[Sulindac co-treated with arsenic trioxide] results in increased cleavage of PARP1 protein]; Sulindac promotes the reaction [Deferoxamine results in increased cleavage of PARP1 protein]
Sulindac results in increased activity of PARP1 protein
CTD PMID:15713900, PMID:18281123, PMID:21882223 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Parp14 poly (ADP-ribose) polymerase family, member 14 decreases expression EXP Sulindac results in decreased expression of PARP14 mRNA CTD PMID:24136188 NCBI chr11:68,105,442...68,137,509
Ensembl chr11:68,105,369...68,137,535
JBrowse link
G Pbrm1 polybromo 1 decreases expression EXP Sulindac results in decreased expression of PBRM1 mRNA CTD PMID:24136188 NCBI chr16:7,103,714...7,202,899
Ensembl chr16:7,103,998...7,200,362
JBrowse link
G Pcbp1 poly(rC) binding protein 1 increases expression EXP Sulindac results in increased expression of PCBP1 mRNA CTD PMID:24136188 NCBI chr 4:118,327,185...118,329,223
Ensembl chr 4:118,327,533...118,328,602
JBrowse link
G Pcdh17 protocadherin 17 decreases expression ISO Sulindac results in decreased expression of PCDH17 mRNA CTD PMID:11906190 NCBI chr15:67,555,835...67,647,990
Ensembl chr15:67,555,835...67,645,088
JBrowse link
G Pck2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) increases expression ISO Sulindac results in increased expression of PCK2 mRNA CTD PMID:11906190 NCBI chr15:34,216,735...34,224,357
Ensembl chr15:34,216,833...34,224,193
JBrowse link
G Pcna proliferating cell nuclear antigen decreases expression
multiple interactions
ISO
EXP
Sulindac results in decreased expression of PCNA protein
epigallocatechin gallate promotes the reaction [Sulindac inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of PCNA protein]]; kaempferol promotes the reaction [Sulindac inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of PCNA protein]]; Sulindac inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of PCNA protein]
CTD PMID:15020200, PMID:29999212 NCBI chr 3:124,880,698...124,884,570
Ensembl chr 3:124,880,698...124,884,570
JBrowse link
G Pdgfa platelet derived growth factor subunit A multiple interactions EXP [Sulindac co-treated with lipopolysaccharide, E coli O55-B5] affects the expression of PDGFA mRNA CTD PMID:20371263 NCBI chr12:17,734,141...17,756,186
Ensembl chr12:17,734,133...17,755,285
JBrowse link
G Pdlim7 PDZ and LIM domain 7 increases expression ISO Sulindac results in increased expression of PDLIM7 mRNA CTD PMID:11906190 NCBI chr17:9,653,510...9,668,715
Ensembl chr17:9,653,561...9,668,712
JBrowse link
G Per1 period circadian regulator 1 decreases expression EXP Sulindac results in decreased expression of PER1 mRNA CTD PMID:24136188 NCBI chr10:55,681,761...55,696,557
Ensembl chr10:55,687,050...55,695,994
JBrowse link
G Pex2 peroxisomal biogenesis factor 2 increases expression EXP Sulindac results in increased expression of PEX2 mRNA CTD PMID:24136188 NCBI chr 2:98,251,756...98,269,185
Ensembl chr 2:98,252,925...98,269,184
JBrowse link
G Pfdn6 prefoldin subunit 6 increases expression EXP Sulindac results in increased expression of PFDN6 mRNA CTD PMID:24136188 NCBI chr20:5,455,974...5,457,448
Ensembl chr20:5,455,974...5,457,444
JBrowse link
G Pgap2 post-GPI attachment to proteins 2 decreases expression EXP Sulindac results in decreased expression of PGAP2 mRNA CTD PMID:24136188 NCBI chr 1:167,309,021...167,335,550
Ensembl chr 1:167,309,051...167,334,741
JBrowse link
G Pi4k2b phosphatidylinositol 4-kinase type 2 beta increases expression EXP Sulindac results in increased expression of PI4K2B mRNA CTD PMID:24136188 NCBI chr14:60,567,968...60,594,821
Ensembl chr14:60,567,967...60,594,844
JBrowse link
G Pi4ka phosphatidylinositol 4-kinase alpha increases expression EXP Sulindac results in increased expression of PI4KA mRNA CTD PMID:24136188 NCBI chr11:87,858,323...87,975,549
Ensembl chr11:87,858,453...87,973,422
JBrowse link
G Pigc phosphatidylinositol glycan anchor biosynthesis, class C increases expression EXP Sulindac results in increased expression of PIGC mRNA CTD PMID:24136188 NCBI chr13:79,886,832...79,889,305
Ensembl chr13:79,886,832...79,889,304
JBrowse link
G Pigy phosphatidylinositol glycan anchor biosynthesis, class Y increases expression EXP Sulindac results in increased expression of PIGY mRNA CTD PMID:24136188 NCBI chr 8:23,167,974...23,170,215
Ensembl chr 8:23,167,974...23,170,209
JBrowse link
G Pisd phosphatidylserine decarboxylase decreases expression EXP Sulindac results in decreased expression of PISD mRNA CTD PMID:24136188 NCBI chr14:83,298,630...83,347,697
Ensembl chr14:83,298,674...83,346,738
JBrowse link
G Pithd1 PITH domain containing 1 increases expression EXP Sulindac results in increased expression of PITHD1 mRNA CTD PMID:24136188 NCBI chr 5:154,322,562...154,333,080
Ensembl chr 5:154,322,551...154,332,940
JBrowse link
G Pkd1 polycystin 1, transient receptor potential channel interacting increases expression ISO Sulindac results in increased expression of PKD1 mRNA CTD PMID:11906190 NCBI chr10:13,914,057...13,962,008
Ensembl chr10:13,915,214...13,962,008
JBrowse link
G Pla2g4a phospholipase A2 group IVA multiple interactions
decreases expression
ISO Sulindac inhibits the reaction [PLA2G4A gene mutant form results in decreased expression of SOD1 protein]
Sulindac results in decreased expression of PLA2G4A mRNA
CTD PMID:10706128, PMID:15816863 NCBI chr13:67,062,252...67,206,688
Ensembl chr13:66,988,937...67,206,693
JBrowse link
G Plat plasminogen activator, tissue type multiple interactions ISO [Sulindac co-treated with epigallocatechin gallate] results in decreased expression of PLAT mRNA CTD PMID:12628509 NCBI chr16:74,098,263...74,122,897
Ensembl chr16:74,098,260...74,122,889
JBrowse link
G Plcg1 phospholipase C, gamma 1 multiple interactions EXP [Sulindac co-treated with lipopolysaccharide, E coli O55-B5] affects the expression of PLCG1 mRNA CTD PMID:20371263 NCBI chr 3:156,727,642...156,758,307
Ensembl chr 3:156,727,642...156,758,307
JBrowse link
G Plec plectin increases expression EXP Sulindac results in increased expression of PLEC mRNA CTD PMID:24136188 NCBI chr 7:117,230,319...117,291,859
Ensembl chr 7:117,230,319...117,289,961
JBrowse link
G Plekhb2 pleckstrin homology domain containing B2 decreases expression EXP Sulindac results in decreased expression of PLEKHB2 mRNA CTD PMID:24136188 NCBI chr 9:41,348,447...41,381,096
Ensembl chr 9:41,348,449...41,381,101
JBrowse link
G Plekhf1 pleckstrin homology and FYVE domain containing 1 increases expression ISO Sulindac results in increased expression of PLEKHF1 mRNA CTD PMID:11906190 NCBI chr 1:94,609,041...94,616,565
Ensembl chr 1:94,609,377...94,610,854
JBrowse link
G Plxna3 plexin A3 increases expression ISO Sulindac results in increased expression of PLXNA3 mRNA CTD PMID:11906190 NCBI chr  X:156,363,400...156,379,433
Ensembl chr  X:156,363,405...156,379,189
JBrowse link
G Pml PML nuclear body scaffold increases expression ISO Sulindac results in increased expression of PML mRNA CTD PMID:16273229 NCBI chr 8:63,002,515...63,034,310
Ensembl chr 8:63,004,870...63,034,226
JBrowse link
G Pole4 DNA polymerase epsilon 4, accessory subunit decreases expression EXP Sulindac results in decreased expression of POLE4 mRNA CTD PMID:24136188 NCBI chr 4:113,491,644...113,497,455
Ensembl chr 4:113,491,644...113,497,455
JBrowse link
G Polr2c RNA polymerase II subunit C decreases expression EXP Sulindac results in decreased expression of POLR2C mRNA CTD PMID:24136188 NCBI chr19:10,575,060...10,581,842
Ensembl chr19:10,575,060...10,581,842
JBrowse link
G Pomp proteasome maturation protein decreases expression EXP Sulindac results in decreased expression of POMP mRNA CTD PMID:24136188 NCBI chr12:8,746,948...8,759,433
Ensembl chr12:8,746,855...8,759,599
JBrowse link
G Pon3 paraoxonase 3 decreases expression EXP Sulindac results in decreased expression of PON3 mRNA CTD PMID:24136188 NCBI chr 4:30,311,981...30,338,679
Ensembl chr 4:30,311,982...30,338,679
JBrowse link
G Ppard peroxisome proliferator-activated receptor delta increases expression
affects response to substance
ISO Sulindac results in increased expression of PPARD protein
PPARD protein affects the susceptibility to Sulindac
CTD PMID:10866668, PMID:21400612 NCBI chr20:7,818,289...7,883,482
Ensembl chr20:7,818,289...7,885,333
JBrowse link
G Ppp2cb protein phosphatase 2 catalytic subunit beta increases expression EXP Sulindac results in increased expression of PPP2CB mRNA CTD PMID:24136188 NCBI chr16:62,273,276...62,294,767
Ensembl chr16:62,273,276...62,294,769
JBrowse link
G Ppp6r1 protein phosphatase 6, regulatory subunit 1 decreases expression EXP Sulindac results in decreased expression of PPP6R1 mRNA CTD PMID:24136188 NCBI chr 1:72,756,819...72,784,492
Ensembl chr 1:72,756,809...72,784,482
JBrowse link
G Ppt1 palmitoyl-protein thioesterase 1 decreases expression EXP Sulindac results in decreased expression of PPT1 mRNA CTD PMID:24136188 NCBI chr 5:140,538,260...140,558,163
Ensembl chr 5:140,538,260...140,558,162
JBrowse link
G Prdm15 PR/SET domain 15 increases expression EXP Sulindac results in increased expression of PRDM15 mRNA CTD PMID:24136188 NCBI chr11:38,294,040...38,354,648
Ensembl chr11:38,293,875...38,351,184
JBrowse link
G Prdx1 peroxiredoxin 1 increases expression EXP Sulindac results in increased expression of PRDX1 mRNA CTD PMID:24136188 NCBI chr 5:135,536,413...135,551,986
Ensembl chr 5:135,536,413...135,551,990
JBrowse link
G Prkaa2 protein kinase AMP-activated catalytic subunit alpha 2 multiple interactions EXP [Sulindac co-treated with lipopolysaccharide, E coli O55-B5] affects the expression of PRKAA2 mRNA CTD PMID:20371263 NCBI chr 5:124,568,845...124,642,569
Ensembl chr 5:124,574,079...124,642,569
JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha multiple interactions EXP [Sulindac co-treated with lipopolysaccharide, E coli O55-B5] affects the expression of PRKACA mRNA CTD PMID:20371263 NCBI chr19:25,095,089...25,118,869
Ensembl chr19:25,095,089...25,118,860
JBrowse link
G Prkacb protein kinase cAMP-activated catalytic subunit beta multiple interactions EXP [Sulindac co-treated with lipopolysaccharide, E coli O55-B5] affects the expression of PRKACB mRNA CTD PMID:20371263 NCBI chr 2:252,602,197...252,691,886
Ensembl chr 2:252,605,307...252,691,886
JBrowse link
G Prkci protein kinase C, iota increases expression EXP Sulindac results in increased expression of PRKCI mRNA CTD PMID:24136188 NCBI chr 2:115,941,998...116,002,550
Ensembl chr 2:115,941,993...116,002,561
JBrowse link
G Prodh1 proline dehydrogenase 1 decreases expression EXP Sulindac results in decreased expression of PRODH mRNA CTD PMID:24136188 NCBI chr11:87,058,478...87,075,785
Ensembl chr11:87,058,616...87,075,785
JBrowse link
G Prorp protein only RNase P catalytic subunit increases expression EXP Sulindac results in increased expression of PRORP mRNA CTD PMID:24136188 NCBI chr 6:76,079,880...76,171,298
Ensembl chr 6:76,079,880...76,171,296
JBrowse link
G Psma5 proteasome 20S subunit alpha 5 decreases expression EXP Sulindac results in decreased expression of PSMA5 mRNA CTD PMID:24136188 NCBI chr 2:211,050,344...211,073,706
Ensembl chr 2:211,050,360...211,073,714
JBrowse link
G Psmb5 proteasome 20S subunit beta 5 increases expression EXP Sulindac results in increased expression of PSMB5 mRNA CTD PMID:24136188 NCBI chr15:33,259,039...33,263,634
Ensembl chr15:33,259,043...33,263,659
JBrowse link
G Psmc2 proteasome 26S subunit, ATPase 2 increases expression EXP Sulindac results in increased expression of PSMC2 mRNA CTD PMID:24136188 NCBI chr 4:9,867,132...9,881,383
Ensembl chr 4:9,867,101...9,881,484
JBrowse link
G Psmc5 proteasome 26S subunit, ATPase 5 decreases expression EXP Sulindac results in decreased expression of PSMC5 mRNA CTD PMID:24136188 NCBI chr10:94,445,877...94,451,811
Ensembl chr10:94,445,877...94,451,811
JBrowse link
G Psmc6 proteasome 26S subunit, ATPase 6 increases expression EXP Sulindac results in increased expression of PSMC6 mRNA CTD PMID:24136188 NCBI chr15:19,667,453...19,688,916
Ensembl chr15:19,667,453...19,688,914
JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 decreases expression
increases expression
EXP Sulindac results in decreased expression of PTGS1 mRNA alternative form
Sulindac results in increased expression of PTGS1 mRNA
CTD PMID:11375891, PMID:12586211 NCBI chr 3:15,560,685...15,582,339
Ensembl chr 3:15,560,712...15,582,344
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
increases expression
decreases expression
decreases activity
ISO
EXP
[Sulindac co-treated with Deferoxamine] results in increased expression of PTGS2 protein; Sulindac inhibits the reaction [Mitomycin results in increased expression of PTGS2 protein]; Sulindac inhibits the reaction [TNF protein results in increased expression of PTGS2 protein]; Sulindac promotes the reaction [cobaltous chloride results in increased expression of PTGS2 protein]
Sulindac results in increased expression of PTGS2 mRNA
Sulindac results in decreased expression of PTGS2 mRNA
Sulindac results in decreased activity of PTGS2 protein
[Olive Oil co-treated with Sulindac] results in decreased expression of PTGS2 protein; epigallocatechin gallate promotes the reaction [Sulindac inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of PTGS2 protein]]; Sulindac inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of PTGS2 protein]
Sulindac results in decreased expression of PTGS2 protein
CTD PMID:10706128, PMID:11375891, PMID:11504793, PMID:11910360, PMID:12586211, PMID:15309441, PMID:15489888, PMID:15793875, PMID:21882223, PMID:29999212 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Ptp4a2 protein tyrosine phosphatase 4A2 increases expression EXP Sulindac results in increased expression of PTP4A2 mRNA CTD PMID:24136188 NCBI chr 5:148,035,501...148,060,752
Ensembl chr 5:148,051,126...148,060,339
JBrowse link
G Ptprn protein tyrosine phosphatase, receptor type, N decreases expression EXP Sulindac results in decreased expression of PTPRN mRNA CTD PMID:24136188 NCBI chr 9:82,446,626...82,462,314
Ensembl chr 9:82,446,633...82,461,903
JBrowse link
G Pus10 pseudouridine synthase 10 increases expression EXP Sulindac results in increased expression of PUS10 mRNA CTD PMID:24136188 NCBI chr14:108,411,941...108,479,696
Ensembl chr14:108,412,152...108,479,781
JBrowse link
G Qtrt1 queuine tRNA-ribosyltransferase catalytic subunit 1 decreases expression EXP Sulindac results in decreased expression of QTRT1 mRNA CTD PMID:24136188 NCBI chr 8:22,447,057...22,454,328
Ensembl chr 8:22,446,661...22,454,439
JBrowse link
G Rab28 RAB28, member RAS oncogene family increases expression EXP Sulindac results in increased expression of RAB28 mRNA CTD PMID:24136188 NCBI chr14:73,888,968...73,963,209
Ensembl chr14:73,889,213...73,963,202
JBrowse link
G Rab2b RAB2B, member RAS oncogene family increases expression EXP Sulindac results in increased expression of RAB2B mRNA CTD PMID:24136188 NCBI chr15:28,675,504...28,696,192
Ensembl chr15:28,677,055...28,696,122
JBrowse link
G Rac2 Rac family small GTPase 2 decreases expression EXP Sulindac results in decreased expression of RAC2 mRNA CTD PMID:24136188 NCBI chr 7:119,769,708...119,797,111
Ensembl chr 7:119,783,849...119,797,098
JBrowse link
G Ramac RNA guanine-7 methyltransferase activating subunit decreases expression EXP Sulindac results in decreased expression of RAMAC mRNA CTD PMID:24136188 NCBI chr 1:143,583,675...143,589,563
Ensembl chr 1:143,583,675...143,589,556
JBrowse link
G Rasa1 RAS p21 protein activator 1 decreases expression EXP Sulindac results in decreased expression of RASA1 mRNA CTD PMID:24136188 NCBI chr 2:13,617,021...13,696,531
Ensembl chr 2:13,616,822...13,696,426
JBrowse link
G Rassf6 Ras association domain family member 6 increases expression EXP Sulindac results in increased expression of RASSF6 mRNA CTD PMID:24136188 NCBI chr14:18,983,852...19,023,921
Ensembl chr14:18,983,853...19,025,971
JBrowse link
G Rb1 RB transcriptional corepressor 1 decreases expression ISO Sulindac results in decreased expression of RB1 protein CTD PMID:16488075 NCBI chr15:55,081,582...55,209,060
Ensembl chr15:55,083,140...55,209,342
JBrowse link
G Rbbp7 RB binding protein 7, chromatin remodeling factor increases expression EXP Sulindac results in increased expression of RBBP7 mRNA CTD PMID:24136188 NCBI chr  X:33,648,682...33,665,821
Ensembl chr  X:33,648,682...33,665,821
JBrowse link
G Rbm42 RNA binding motif protein 42 decreases expression EXP Sulindac results in decreased expression of RBM42 mRNA CTD PMID:24136188 NCBI chr 1:89,099,296...89,109,248
Ensembl chr 1:89,099,277...89,109,230
JBrowse link
G Rbm45 RNA binding motif protein 45 increases expression EXP Sulindac results in increased expression of RBM45 mRNA CTD PMID:24136188 NCBI chr 3:63,220,660...63,235,638
Ensembl chr 3:63,220,647...63,235,648
JBrowse link
G Rbm47 RNA binding motif protein 47 decreases expression EXP Sulindac results in decreased expression of RBM47 mRNA CTD PMID:24136188 NCBI chr14:43,701,944...43,839,803
Ensembl chr14:43,810,119...43,837,662
JBrowse link
G Rbx1 ring-box 1 increases expression EXP Sulindac results in increased expression of RBX1 mRNA CTD PMID:24136188 NCBI chr 7:122,700,849...122,710,907
Ensembl chr 7:122,700,854...122,709,935
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit affects localization
increases activity
increases expression
multiple interactions
ISO Sulindac affects the localization of RELA protein
Sulindac results in increased activity of RELA protein
Sulindac results in increased expression of RELA mRNA
[[Sulindac co-treated with Arsenic Trioxide] results in decreased phosphorylation of and results in decreased degradation of NFKBIA protein] which affects the localization of RELA protein; Sulindac inhibits the reaction [Lipopolysaccharides results in increased expression of RELA protein]; Sulindac inhibits the reaction [TNF protein results in increased activity of [NFKB1 protein binds to RELA protein]]; Sulindac inhibits the reaction [TNF protein results in increased activity of RELA protein]
CTD PMID:10328874, PMID:15489888, PMID:16159934, PMID:16273229, PMID:18059344, PMID:18575716 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Ren renin multiple interactions
decreases activity
ISO Sulindac inhibits the reaction [Furosemide results in increased expression of REN protein]
Sulindac results in decreased activity of REN protein
CTD PMID:2203262, PMID:3884224, PMID:4028619 NCBI chr13:50,502,724...50,513,953
Ensembl chr13:50,502,724...50,514,151
JBrowse link
G Ret ret proto-oncogene affects expression ISO Sulindac affects the expression of RET protein CTD PMID:12388792 NCBI chr 4:150,202,170...150,249,196
Ensembl chr 4:150,202,058...150,244,372
JBrowse link
G RGD1306063 similar to HT021 decreases expression EXP Sulindac results in decreased expression of RGD1306063 mRNA CTD PMID:24136188 NCBI chr15:12,869,217...12,889,144
Ensembl chr15:12,872,408...12,889,108
JBrowse link
G RGD1308147 similar to expressed sequence AW209491 decreases expression EXP Sulindac results in decreased expression of RGD1308147 mRNA CTD PMID:24136188 NCBI chr17:53,080,629...53,087,335
Ensembl chr17:53,080,638...53,087,274
JBrowse link
G RGD1311745 similar to RIKEN cDNA 1110059G10 increases expression EXP Sulindac results in increased expression of RGD1311745 mRNA CTD PMID:24136188 NCBI chr 8:132,029,618...132,032,971
Ensembl chr 8:132,029,621...132,036,472
JBrowse link
G RGD1560065 similar to RIKEN cDNA 2410004B18 increases expression ISO Sulindac results in increased expression of C1ORF52 mRNA CTD PMID:11906190 NCBI chr 2:251,817,862...251,824,784
Ensembl chr 2:251,817,694...251,824,784
JBrowse link
G RGD1562987 similar to cDNA sequence BC031181 decreases expression EXP Sulindac results in decreased expression of RGD1562987 mRNA CTD PMID:24136188 NCBI chr18:70,974,885...70,983,362
Ensembl chr18:70,974,885...70,983,360
JBrowse link
G RGD1565784 RGD1565784 increases expression EXP Sulindac results in increased expression of RGD1565784 mRNA CTD PMID:24136188 NCBI chr10:14,543,196...14,544,498
Ensembl chr10:14,543,200...14,545,000
JBrowse link
G Rgp1 RGP1 homolog, RAB6A GEF complex partner 1 increases expression EXP Sulindac results in increased expression of RGP1 mRNA CTD PMID:24136188 NCBI chr 5:59,080,290...59,088,777
Ensembl chr 5:59,080,765...59,088,523
JBrowse link
G Rmdn3 regulator of microtubule dynamics 3 decreases expression EXP Sulindac results in decreased expression of RMDN3 mRNA CTD PMID:24136188 NCBI chr 3:110,943,843...110,964,449
Ensembl chr 3:110,943,826...110,964,452
JBrowse link
G Rnase1 ribonuclease A family member 1, pancreatic decreases expression ISO Sulindac results in decreased expression of RNASE1 mRNA CTD PMID:11906190
G Rnf220 ring finger protein 220 increases expression EXP Sulindac results in increased expression of RNF220 mRNA CTD PMID:24136188 NCBI chr 5:136,129,457...136,351,752
Ensembl chr 5:136,129,425...136,166,786
JBrowse link
G Rnf26 ring finger protein 26 decreases expression ISO Sulindac results in decreased expression of RNF26 mRNA CTD PMID:11906190 NCBI chr 8:48,447,113...48,449,311
Ensembl chr 8:48,447,113...48,449,311
JBrowse link
G Rnpepl1 arginyl aminopeptidase like 1 decreases expression EXP Sulindac results in decreased expression of RNPEPL1 mRNA CTD PMID:24136188 NCBI chr 9:100,080,144...100,089,834
Ensembl chr 9:100,080,144...100,089,834
JBrowse link
G Rpia ribose 5-phosphate isomerase A decreases expression EXP Sulindac results in decreased expression of RPIA mRNA CTD PMID:24136188 NCBI chr 4:98,568,028...98,593,664
Ensembl chr 4:98,568,028...98,593,664
JBrowse link
G Rragc Ras-related GTP binding C decreases expression EXP Sulindac results in decreased expression of RRAGC mRNA CTD PMID:24136188 NCBI chr 5:141,572,536...141,590,784
Ensembl chr 5:141,572,536...141,590,781
JBrowse link
G Rxra retinoid X receptor alpha multiple interactions EXP [Sulindac co-treated with lipopolysaccharide, E coli O55-B5] affects the expression of RXRA mRNA CTD PMID:20371263 NCBI chr 3:6,272,560...6,295,354
Ensembl chr 3:6,211,789...6,295,908
JBrowse link
G Sae1 SUMO1 activating enzyme subunit 1 decreases expression EXP Sulindac results in decreased expression of SAE1 mRNA CTD PMID:24136188 NCBI chr 1:78,277,524...78,333,281
Ensembl chr 1:78,277,515...78,333,321
JBrowse link
G Sap30l SAP30-like decreases expression EXP Sulindac results in decreased expression of SAP30L mRNA CTD PMID:24136188 NCBI chr10:43,224,151...43,231,864
Ensembl chr10:43,224,269...43,231,611
JBrowse link
G Sat1 spermidine/spermine N1-acetyl transferase 1 increases expression ISO Sulindac results in increased expression of SAT1 mRNA CTD PMID:14506281, PMID:16262603 NCBI chr  X:43,626,480...43,629,767
Ensembl chr  X:43,625,169...43,629,765
JBrowse link
G Sat2 spermidine/spermine N1-acetyltransferase family member 2 increases activity
increases expression
ISO Sulindac results in increased activity of SAT2 protein
Sulindac results in increased expression of SAT2 mRNA
CTD PMID:17474863 NCBI chr10:56,227,703...56,229,796
Ensembl chr10:56,227,692...56,229,850
JBrowse link
G Scamp1 secretory carrier membrane protein 1 increases expression EXP Sulindac results in increased expression of SCAMP1 mRNA CTD PMID:24136188 NCBI chr 2:23,858,021...23,941,128
Ensembl chr 2:23,857,995...23,941,084
JBrowse link
G Sco1 synthesis of cytochrome C oxidase 1 increases expression EXP Sulindac results in increased expression of SCO1 mRNA CTD PMID:24136188 NCBI chr10:53,595,854...53,608,437
Ensembl chr10:53,595,854...53,608,435
JBrowse link
G Sdhaf3 succinate dehydrogenase complex assembly factor 3 increases expression EXP Sulindac results in increased expression of SDHAF3 mRNA CTD PMID:24136188 NCBI chr 4:32,541,706...32,558,798
Ensembl chr 4:32,495,321...32,558,798
JBrowse link
G Sec62 SEC62 homolog, preprotein translocation factor decreases expression EXP Sulindac results in decreased expression of SEC62 mRNA CTD PMID:24136188 NCBI chr 2:116,188,736...116,225,510
Ensembl chr 2:116,189,862...116,219,750
JBrowse link
G Sec63 SEC63 homolog, protein translocation regulator decreases expression EXP Sulindac results in decreased expression of SEC63 mRNA CTD PMID:24136188 NCBI chr20:47,494,270...47,563,222
Ensembl chr20:47,494,270...47,563,222
JBrowse link
G Septin10 septin 10 decreases expression EXP Sulindac results in decreased expression of SEPTIN10 mRNA CTD PMID:24136188 NCBI chr20:28,722,479...28,814,841
Ensembl chr20:28,722,580...28,814,636
JBrowse link
G Serpinb1a serpin family B member 1A increases expression ISO Sulindac results in increased expression of SERPINB1 mRNA CTD PMID:11507085 NCBI chr17:32,903,089...32,911,498
Ensembl chr17:32,904,119...32,911,495
JBrowse link
G Set SET nuclear proto-oncogene decreases expression EXP Sulindac results in decreased expression of SET mRNA CTD PMID:24136188 NCBI chr19:58,420,635...58,422,153
Ensembl chr19:58,419,961...58,421,504
JBrowse link
G Sft2d2 SFT2 domain containing 2 increases expression EXP Sulindac results in increased expression of SFT2D2 mRNA CTD PMID:24136188 NCBI chr13:83,438,635...83,457,899
Ensembl chr13:83,438,493...83,457,888
JBrowse link
G Shc1 SHC adaptor protein 1 multiple interactions ISO Sulindac inhibits the reaction [CDKN1A protein results in increased expression of SHC1 mRNA] CTD PMID:15190207 NCBI chr 2:188,745,503...188,757,066
Ensembl chr 2:188,745,503...188,757,066
JBrowse link
G Shmt2 serine hydroxymethyltransferase 2 increases expression EXP Sulindac results in increased expression of SHMT2 mRNA CTD PMID:24136188 NCBI chr 7:70,824,718...70,829,822
Ensembl chr 7:70,824,715...70,829,815
JBrowse link
G Sirt1 sirtuin 1 increases expression ISO Sulindac results in increased expression of SIRT1 mRNA CTD PMID:11906190 NCBI chr20:26,831,971...26,851,587
Ensembl chr20:26,833,357...26,852,199
JBrowse link
G Slc16a6 solute carrier family 16, member 6 increases expression ISO Sulindac results in increased expression of SLC16A6 mRNA CTD PMID:11906190 NCBI chr10:97,733,701...97,758,723
Ensembl chr10:97,735,548...97,756,521
JBrowse link
G Slc18b1 solute carrier family 18 member B1 increases expression EXP Sulindac results in increased expression of SLC18B1 mRNA CTD PMID:24136188 NCBI chr 1:22,705,980...22,748,571
Ensembl chr 1:22,705,916...22,748,422
JBrowse link
G Slc22a1 solute carrier family 22 member 1 decreases activity ISO Sulindac results in decreased activity of SLC22A1 protein CTD PMID:12388633 NCBI chr 1:48,273,639...48,300,645
Ensembl chr 1:48,273,611...48,300,655
JBrowse link
G Slc22a2 solute carrier family 22 member 2 decreases activity ISO Sulindac results in decreased activity of SLC22A2 protein CTD PMID:12388633 NCBI chr 1:48,318,025...48,360,219
Ensembl chr 1:48,317,995...48,360,261
JBrowse link
G Slc22a25 solute carrier family 22, member 25 decreases activity ISO Sulindac results in decreased activity of SLC22A9 protein CTD PMID:12388633 NCBI chr 1:224,596,886...224,698,512
Ensembl chr 1:224,596,887...224,698,514
JBrowse link
G Slc22a6 solute carrier family 22 member 6 decreases activity ISO Sulindac results in decreased activity of SLC22A6 protein CTD PMID:12388633 NCBI chr 1:224,824,809...224,833,284
Ensembl chr 1:224,824,799...224,833,259
JBrowse link
G Slc22a7 solute carrier family 22 member 7 decreases activity ISO Sulindac results in decreased activity of SLC22A7 protein CTD PMID:12388633 NCBI chr 9:16,925,321...16,931,119
Ensembl chr 9:16,924,520...16,931,766
JBrowse link
G Slc27a4 solute carrier family 27 member 4 decreases expression EXP Sulindac results in decreased expression of SLC27A4 mRNA CTD PMID:24136188 NCBI chr 3:8,363,937...8,376,858
Ensembl chr 3:8,363,937...8,376,858
JBrowse link
G Slc30a1 solute carrier family 30 member 1 increases expression ISO Sulindac results in increased expression of SLC30A1 mRNA CTD PMID:11906190 NCBI chr13:110,677,810...110,681,683
Ensembl chr13:110,677,810...110,681,683
JBrowse link
G Slc30a5 solute carrier family 30 member 5 decreases expression EXP Sulindac results in decreased expression of SLC30A5 mRNA CTD PMID:24136188 NCBI chr 2:30,815,683...30,845,796
Ensembl chr 2:30,815,703...30,846,149
JBrowse link
G Slc38a2 solute carrier family 38, member 2 increases expression ISO Sulindac results in increased expression of SLC38A2 mRNA CTD PMID:11906190 NCBI chr 7:138,088,654...138,100,869
Ensembl chr 7:138,088,649...138,100,841
JBrowse link
G Slc3a2 solute carrier family 3 member 2 increases expression ISO Sulindac results in increased expression of SLC3A2 mRNA CTD PMID:11906190 NCBI chr 1:224,906,566...224,921,029
Ensembl chr 1:224,906,554...224,921,092
JBrowse link
G Slc4a1ap solute carrier family 4 member 1 adaptor protein decreases expression EXP Sulindac results in decreased expression of SLC4A1AP mRNA CTD PMID:24136188 NCBI chr 6:26,214,083...26,241,337
Ensembl chr 6:26,214,335...26,241,337
JBrowse link
G Slc7a1 solute carrier family 7 member 1 increases expression ISO Sulindac results in increased expression of SLC7A1 mRNA CTD PMID:11906190 NCBI chr12:8,032,775...8,108,972
Ensembl chr12:8,032,809...8,108,972
JBrowse link
G Slco1a4 solute carrier organic anion transporter family, member 1a4 multiple interactions EXP [Sulindac co-treated with lipopolysaccharide, E coli O55-B5] affects the expression of SLCO1A2 mRNA CTD PMID:20371263 NCBI chr 4:175,969,549...176,026,227
Ensembl chr 4:175,969,549...176,026,163
JBrowse link
G Slfn3 schlafen family member 3 decreases expression EXP Sulindac results in decreased expression of SLFN3 mRNA CTD PMID:24136188 NCBI chr10:70,438,012...70,477,259 JBrowse link
G Smc1a structural maintenance of chromosomes 1A decreases expression EXP Sulindac results in decreased expression of SMC1A mRNA CTD PMID:24136188 NCBI chr  X:21,710,976...21,755,708
Ensembl chr  X:21,711,019...21,755,525
JBrowse link
G Smu1 SMU1, DNA replication regulator and spliceosomal factor decreases expression EXP Sulindac results in decreased expression of SMU1 mRNA CTD PMID:24136188 NCBI chr 5:57,042,301...57,061,379
Ensembl chr 5:57,042,705...57,061,365
JBrowse link
G Snrnp27 small nuclear ribonucleoprotein U4/U6.U5 subunit 27 increases expression EXP Sulindac results in increased expression of SNRNP27 mRNA CTD PMID:24136188 NCBI chr 4:118,478,075...118,487,633
Ensembl chr 4:118,478,075...118,534,280
JBrowse link
G Snx21 sorting nexin family member 21 increases expression ISO Sulindac results in increased expression of SNX21 mRNA CTD PMID:11906190 NCBI chr 3:161,252,634...161,261,880
Ensembl chr 3:161,252,723...161,264,818
JBrowse link
G Snx25 sorting nexin 25 increases expression ISO Sulindac results in increased expression of SNX25 mRNA CTD PMID:11906190 NCBI chr16:49,328,958...49,432,415
Ensembl chr16:49,350,884...49,432,118
JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions ISO Sulindac inhibits the reaction [PLA2G4A gene mutant form results in decreased expression of SOD1 protein] CTD PMID:15816863 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions ISO Sulindac inhibits the reaction [CDKN1A protein results in increased expression of SOD2 mRNA] CTD PMID:15190207 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Spred3 sprouty-related, EVH1 domain containing 3 decreases expression EXP Sulindac results in decreased expression of SPRED3 mRNA CTD PMID:24136188 NCBI chr 1:88,101,213...88,112,719
Ensembl chr 1:88,103,719...88,112,683
JBrowse link
G Sqstm1 sequestosome 1 increases expression ISO Sulindac results in increased expression of SQSTM1 mRNA CTD PMID:11906190 NCBI chr10:35,704,728...35,716,316
Ensembl chr10:35,704,730...35,716,294
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase multiple interactions EXP
ISO
[[Azoxymethane co-treated with Sulindac] results in increased expression of CSK protein] which results in increased phosphorylation of and results in decreased activity of SRC protein
Sulindac results in increased phosphorylation of and results in decreased activity of SRC protein
CTD PMID:18644992 NCBI chr 3:153,547,807...153,595,643
Ensembl chr 3:153,580,861...153,595,642
JBrowse link
G Srxn1 sulfiredoxin 1 increases expression ISO Sulindac results in increased expression of SRXN1 protein CTD PMID:27358234 NCBI chr 3:147,608,850...147,614,410
Ensembl chr 3:147,609,095...147,632,801
JBrowse link
G Ss18 SS18 subunit of BAF chromatin remodeling complex decreases expression EXP Sulindac results in decreased expression of SS18 mRNA CTD PMID:24136188 NCBI chr18:6,020,267...6,083,055
Ensembl chr18:6,020,267...6,083,033
JBrowse link
G Ssu72 SSU72 homolog, RNA polymerase II CTD phosphatase decreases expression EXP Sulindac results in decreased expression of SSU72 mRNA CTD PMID:24136188 NCBI chr 5:173,152,964...173,182,720
Ensembl chr 5:173,152,964...173,182,719
JBrowse link
G Stac3 SH3 and cysteine rich domain 3 decreases expression EXP Sulindac results in decreased expression of STAC3 mRNA CTD PMID:24136188 NCBI chr 7:70,807,427...70,815,271
Ensembl chr 7:70,807,867...70,815,270
JBrowse link
G Stard3 StAR-related lipid transfer domain containing 3 increases expression EXP Sulindac results in increased expression of STARD3 mRNA CTD PMID:24136188 NCBI chr10:86,313,430...86,335,868
Ensembl chr10:86,313,383...86,335,923
JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions
decreases expression
decreases phosphorylation
ISO BIRC5 protein inhibits the reaction [Sulindac results in decreased expression of STAT3 protein modified form]; BIRC5 protein inhibits the reaction [Sulindac results in decreased expression of STAT3 protein]
Sulindac results in decreased expression of STAT3 protein; Sulindac results in decreased expression of STAT3 protein modified form
Sulindac results in decreased phosphorylation of STAT3 protein
CTD PMID:11861373, PMID:17401459 NCBI chr10:88,790,401...88,842,263
Ensembl chr10:88,790,408...88,842,233
JBrowse link
G Stc2 stanniocalcin 2 increases expression ISO Sulindac results in increased expression of STC2 mRNA CTD PMID:11906190 NCBI chr10:16,542,909...16,552,675
Ensembl chr10:16,542,882...16,553,295
JBrowse link
G Stoml2 stomatin like 2 increases expression EXP Sulindac results in increased expression of STOML2 mRNA CTD PMID:24136188 NCBI chr 5:58,472,561...58,476,158
Ensembl chr 5:58,472,550...58,476,251
JBrowse link
G Strbp spermatid perinuclear RNA binding protein increases expression EXP Sulindac results in increased expression of STRBP mRNA CTD PMID:24136188 NCBI chr 3:21,817,680...21,956,988
Ensembl chr 3:21,828,298...21,904,270
JBrowse link
G Stx7 syntaxin 7 decreases expression EXP Sulindac results in decreased expression of STX7 mRNA CTD PMID:24136188 NCBI chr 1:22,241,655...22,281,850
Ensembl chr 1:22,241,661...22,281,788
JBrowse link
G Stxbp2 syntaxin binding protein 2 increases expression ISO Sulindac results in increased expression of STXBP2 mRNA CTD PMID:11906190 NCBI chr12:2,180,101...2,191,863
Ensembl chr12:2,180,150...2,191,175
JBrowse link
G Suclg1 succinate-CoA ligase GDP/ADP-forming subunit alpha increases expression EXP Sulindac results in increased expression of SUCLG1 mRNA CTD PMID:24136188 NCBI chr 4:101,181,315...101,210,692
Ensembl chr 4:101,180,404...101,210,746
JBrowse link
G Sult1b1 sulfotransferase family 1B member 1 multiple interactions EXP [Sulindac co-treated with lipopolysaccharide, E coli O55-B5] affects the expression of SULT1B1 mRNA CTD PMID:20371263 NCBI chr14:22,142,412...22,155,246
Ensembl chr14:22,142,364...22,155,231
JBrowse link
G Sult1e1 sulfotransferase family 1E member 1 multiple interactions
decreases activity
EXP
ISO
[Sulindac co-treated with lipopolysaccharide, E coli O55-B5] affects the expression of SULT1E1 mRNA
Sulindac results in decreased activity of SULT1E1 protein
CTD PMID:17073578, PMID:20371263 NCBI chr14:22,070,861...22,089,264
Ensembl chr14:22,072,024...22,089,248
JBrowse link
G Sumo3 small ubiquitin-like modifier 3 decreases expression ISO Sulindac results in decreased expression of SUMO3 mRNA CTD PMID:11906190 NCBI chr20:11,726,488...11,737,050
Ensembl chr20:11,726,497...11,737,050
JBrowse link
G Sun2 Sad1 and UNC84 domain containing 2 decreases expression ISO Sulindac results in decreased expression of SUN2 mRNA CTD PMID:11906190 NCBI chr 7:120,950,391...120,967,583
Ensembl chr 7:120,951,560...120,967,490
JBrowse link
G Supt7l SPT7 like, STAGA complex subunit gamma decreases expression EXP Sulindac results in decreased expression of SUPT7L mRNA CTD PMID:24136188 NCBI chr 6:26,241,672...26,251,810
Ensembl chr 6:26,241,672...26,251,809
JBrowse link
G Syp synaptophysin decreases expression EXP Sulindac results in decreased expression of SYP mRNA CTD PMID:24136188 NCBI chr  X:15,694,699...15,709,244
Ensembl chr  X:15,695,566...15,707,436
JBrowse link
G Syt15 synaptotagmin 15 decreases expression EXP Sulindac results in decreased expression of SYT15 mRNA CTD PMID:24136188 NCBI chr16:10,554,136...10,564,934
Ensembl chr16:10,554,136...10,564,927
JBrowse link
G Tbc1d10b TBC1 domain family, member 10b increases expression ISO Sulindac results in increased expression of TBC1D10B mRNA CTD PMID:11906190 NCBI chr 1:198,641,018...198,652,674
Ensembl chr 1:198,641,018...198,652,674
JBrowse link
G Tbk1 TANK-binding kinase 1 increases expression ISO Sulindac results in increased expression of TBK1 mRNA CTD PMID:11093808 NCBI chr 7:63,655,247...63,687,978
Ensembl chr 7:63,655,247...63,687,978
JBrowse link
G Tbx3 T-box transcription factor 3 increases expression ISO Sulindac results in increased expression of TBX3 mRNA CTD PMID:11906190 NCBI chr12:42,479,518...42,494,588
Ensembl chr12:42,480,560...42,492,526
JBrowse link
G Tceanc2 transcription elongation factor A N-terminal and central domain containing 2 increases expression EXP Sulindac results in increased expression of TCEANC2 mRNA CTD PMID:24136188 NCBI chr 5:126,746,165...126,782,726
Ensembl chr 5:126,746,172...126,782,726
JBrowse link
G Tcf4 transcription factor 4 decreases activity
multiple interactions
ISO Sulindac results in decreased activity of TCF4 protein
TCF4 protein promotes the reaction [Sulindac results in increased susceptibility to TNFSF10 protein]
CTD PMID:11593435, PMID:21171083 NCBI chr18:65,285,320...65,507,983
Ensembl chr18:65,155,685...65,507,977
JBrowse link
G Tdo2 tryptophan 2,3-dioxygenase decreases activity
multiple interactions
EXP Sulindac results in decreased activity of TDO2 protein
[Sulindac results in decreased activity of TDO2 protein] which results in decreased abundance of Dopamine; [Sulindac results in decreased activity of TDO2 protein] which results in increased abundance of Serotonin
CTD PMID:16952380 NCBI chr 2:180,897,059...180,914,919
Ensembl chr 2:180,897,011...180,914,940
JBrowse link
G Tek TEK receptor tyrosine kinase multiple interactions ISO Sulindac analog results in decreased phosphorylation of and results in decreased activity of TEK protein CTD PMID:16215210 NCBI chr 5:113,725,717...113,852,799
Ensembl chr 5:113,725,717...113,852,799
JBrowse link
G Tfdp1 transcription factor Dp-1 decreases expression EXP Sulindac results in decreased expression of TFDP1 mRNA CTD PMID:24136188 NCBI chr16:81,088,642...81,127,244
Ensembl chr16:81,089,292...81,127,257
JBrowse link
G Tgfb1 transforming growth factor, beta 1 increases expression ISO Sulindac results in increased expression of TGFB1 protein CTD PMID:11496082 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Tgm2 transglutaminase 2 multiple interactions ISO Sulindac inhibits the reaction [CDKN1A protein results in increased expression of TGM2 mRNA] CTD PMID:15190207 NCBI chr 3:154,597,165...154,627,257
Ensembl chr 3:154,597,168...154,627,257
JBrowse link
G Thap7 THAP domain containing 7 increases expression EXP Sulindac results in increased expression of THAP7 mRNA CTD PMID:24136188 NCBI chr11:87,399,430...87,403,381
Ensembl chr11:87,399,483...87,403,367
JBrowse link
G Thrsp thyroid hormone responsive decreases expression EXP Sulindac results in decreased expression of THRSP mRNA CTD PMID:24136188 NCBI chr 1:162,381,251...162,385,575
Ensembl chr 1:162,381,253...162,385,575
JBrowse link
G Timm10 translocase of inner mitochondrial membrane 10 increases expression EXP Sulindac results in increased expression of TIMM10 mRNA CTD PMID:24136188 NCBI chr 3:72,226,563...72,230,087
Ensembl chr 3:72,226,613...72,230,084
JBrowse link
G Timmdc1 translocase of inner mitochondrial membrane domain containing 1 increases expression EXP Sulindac results in increased expression of TIMMDC1 mRNA CTD PMID:24136188 NCBI chr11:64,790,801...64,815,484
Ensembl chr11:64,790,801...64,815,477
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 affects expression ISO Sulindac affects the expression of TIMP1 protein CTD PMID:12388792 NCBI chr  X:1,364,771...1,369,451
Ensembl chr  X:1,364,786...1,369,384
JBrowse link
G Timp3 TIMP metallopeptidase inhibitor 3 multiple interactions ISO [Sulindac co-treated with epigallocatechin gallate] results in decreased expression of TIMP3 mRNA CTD PMID:12628509 NCBI chr 7:23,543,125...23,594,170
Ensembl chr 7:23,544,215...23,594,133
JBrowse link
G Tjp2 tight junction protein 2 increases expression EXP Sulindac results in increased expression of TJP2 mRNA CTD PMID:24136188 NCBI chr 1:241,945,816...242,084,044
Ensembl chr 1:241,945,841...242,083,484
JBrowse link
G Tlr2 toll-like receptor 2 multiple interactions EXP [Sulindac co-treated with lipopolysaccharide, E coli O55-B5] affects the expression of TLR2 mRNA CTD PMID:20371263 NCBI chr 2:182,840,171...182,846,061
Ensembl chr 2:182,840,727...182,846,061
JBrowse link
G Tm2d1 TM2 domain containing 1 increases expression EXP Sulindac results in increased expression of TM2D1 mRNA CTD PMID:24136188 NCBI chr 5:116,992,405...117,038,882
Ensembl chr 5:116,996,652...117,038,882
JBrowse link
G Tm7sf3 transmembrane 7 superfamily member 3 decreases expression ISO Sulindac results in decreased expression of TM7SF3 mRNA CTD PMID:11093808 NCBI chr 4:180,913,703...180,951,564
Ensembl chr 4:180,913,706...180,951,564
JBrowse link
G Tmed9 transmembrane p24 trafficking protein 9 decreases expression ISO Sulindac results in decreased expression of TMED9 mRNA CTD PMID:11906190 NCBI chr17:9,560,735...9,565,249
Ensembl chr17:9,560,761...9,565,249
JBrowse link
G Tmem127 transmembrane protein 127 increases expression ISO Sulindac results in increased expression of TMEM127 mRNA CTD PMID:11906190 NCBI chr 3:119,677,575...119,690,371
Ensembl chr 3:119,677,575...119,690,366
JBrowse link
G Tmem141 transmembrane protein 141 increases expression EXP Sulindac results in increased expression of TMEM141 mRNA CTD PMID:24136188 NCBI chr 3:2,843,635...2,845,593
Ensembl chr 3:2,843,635...2,845,593
JBrowse link
G Tmem209 transmembrane protein 209 decreases expression EXP Sulindac results in decreased expression of TMEM209 mRNA CTD PMID:24136188 NCBI chr 4:57,796,337...57,823,283
Ensembl chr 4:57,796,338...57,823,295
JBrowse link
G Tmem39a transmembrane protein 39a increases expression ISO Sulindac results in increased expression of TMEM39A mRNA CTD PMID:11906190 NCBI chr11:64,723,181...64,752,514
Ensembl chr11:64,723,186...64,752,544
JBrowse link
G Tmem60 transmembrane protein 60 increases expression EXP Sulindac results in increased expression of TMEM60 mRNA CTD PMID:24136188 NCBI chr 4:10,818,024...10,822,879
Ensembl chr 4:10,818,024...10,822,879
JBrowse link
G Tmx1 thioredoxin-related transmembrane protein 1 increases expression EXP Sulindac results in increased expression of TMX1 mRNA CTD PMID:24136188 NCBI chr 6:92,864,123...92,875,141
Ensembl chr 6:92,864,123...92,874,204
JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression
ISO
EXP
Sulindac inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; Sulindac inhibits the reaction [TNF protein results in increased activity of [NFKB1 protein binds to RELA protein]]; Sulindac inhibits the reaction [TNF protein results in increased activity of CHUK protein]; Sulindac inhibits the reaction [TNF protein results in increased activity of NFKB1 protein]; Sulindac inhibits the reaction [TNF protein results in increased activity of RELA protein]; Sulindac inhibits the reaction [TNF protein results in increased degradation of NFKBIA protein]; Sulindac inhibits the reaction [TNF protein results in increased expression of CCL5 mRNA]; Sulindac inhibits the reaction [TNF protein results in increased expression of CCND1 protein]; Sulindac inhibits the reaction [TNF protein results in increased expression of PTGS2 protein]
Sulindac results in increased expression of TNF
[Sulindac co-treated with Lipopolysaccharides] results in increased secretion of TNF protein; Sulindac inhibits the reaction [Okadaic Acid results in increased expression of TNF protein]
CTD PMID:10328874, PMID:10757128, PMID:15489888, PMID:16159934, PMID:17328244, PMID:24136188 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfsf10 TNF superfamily member 10 increases response to substance
multiple interactions
ISO Sulindac results in increased susceptibility to TNFSF10 protein
[Sulindac co-treated with TNFSF10 protein] results in increased activity of CASP8 protein; TCF4 protein promotes the reaction [Sulindac results in increased susceptibility to TNFSF10 protein]
CTD PMID:21171083 NCBI chr 2:113,008,008...113,026,899
Ensembl chr 2:113,007,549...113,026,899
JBrowse link
G Tns3 tensin 3 decreases expression ISO Sulindac results in decreased expression of TNS3 mRNA CTD PMID:11906190 NCBI chr14:88,673,922...88,907,874
Ensembl chr14:88,673,881...88,886,198
JBrowse link
G Tor1a torsin family 1, member A decreases expression EXP Sulindac results in decreased expression of TOR1A mRNA CTD PMID:24136188 NCBI chr 3:9,800,322...9,807,318
Ensembl chr 3:9,800,322...9,807,328
JBrowse link
G Tp53 tumor protein p53 multiple interactions
decreases expression
increases expression
affects localization
ISO [Sulindac results in increased abundance of Reactive Oxygen Species] which results in increased activity of TP53 protein; SB 203580 inhibits the reaction [Sulindac affects the localization of TP53 protein]
Sulindac results in decreased expression of TRP53 protein
Sulindac results in increased expression of TP53 protein
CTD PMID:15020200, PMID:15713900, PMID:17136320 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Tpra1 transmembrane protein adipocyte associated 1 increases expression ISO Sulindac results in increased expression of TPRA1 mRNA CTD PMID:11906190 NCBI chr 4:120,843,374...120,854,534
Ensembl chr 4:120,843,453...120,854,529
JBrowse link
G Trim2 tripartite motif-containing 2 increases expression ISO Sulindac results in increased expression of TRIM2 mRNA CTD PMID:11906190 NCBI chr 2:183,145,096...183,223,819
Ensembl chr 2:183,145,089...183,213,228
JBrowse link
G Trit1 tRNA isopentenyltransferase 1 decreases expression ISO Sulindac results in decreased expression of TRIT1 mRNA CTD PMID:11906190 NCBI chr 5:140,711,943...140,756,893
Ensembl chr 5:140,712,583...140,756,085
JBrowse link
G Trub2 TruB pseudouridine synthase family member 2 increases expression EXP Sulindac results in increased expression of TRUB2 mRNA CTD PMID:24136188 NCBI chr 3:8,338,479...8,348,746
Ensembl chr 3:8,338,484...8,348,746
JBrowse link
G Tsnax translin-associated factor X decreases expression ISO Sulindac results in decreased expression of TSNAX mRNA CTD PMID:11906190 NCBI chr19:57,771,539...57,785,567
Ensembl chr19:57,771,398...57,785,543
JBrowse link
G Tusc2 tumor suppressor 2, mitochondrial calcium regulator increases expression EXP Sulindac results in increased expression of TUSC2 mRNA CTD PMID:24136188 NCBI chr 8:116,318,963...116,322,181
Ensembl chr 8:116,318,963...116,322,181
JBrowse link
G Txn1 thioredoxin 1 increases response to substance ISO TXN1 results in increased susceptibility to Sulindac analog CTD PMID:18922898 NCBI chr 5:75,049,735...75,057,731
Ensembl chr 5:75,049,747...75,057,752
JBrowse link
G Txnl1 thioredoxin-like 1 increases expression EXP Sulindac results in increased expression of TXNL1 mRNA CTD PMID:24136188 NCBI chr18:59,056,454...59,086,278
Ensembl chr18:59,059,375...59,086,256
JBrowse link
G Tyw1 tRNA-yW synthesizing protein 1 homolog increases expression EXP Sulindac results in increased expression of TYW1 mRNA CTD PMID:24136188 NCBI chr12:29,824,990...29,919,240
Ensembl chr12:29,824,981...29,919,320
JBrowse link
G Ube2e3 ubiquitin-conjugating enzyme E2E 3 decreases expression EXP Sulindac results in decreased expression of UBE2E3 mRNA CTD PMID:24136188 NCBI chr 3:65,815,076...65,876,256
Ensembl chr 3:65,815,080...65,871,363
JBrowse link
G Ube3a ubiquitin protein ligase E3A increases expression EXP Sulindac results in increased expression of UBE3A mRNA CTD PMID:24136188 NCBI chr 1:116,586,901...116,678,161
Ensembl chr 1:116,587,815...116,679,973
JBrowse link
G Ubl5 ubiquitin-like 5 decreases expression EXP Sulindac results in decreased expression of UBL5 mRNA CTD PMID:24136188 NCBI chr 8:21,663,257...21,665,049
Ensembl chr 8:21,663,325...21,665,038
JBrowse link
G Ubqln2 ubiquilin 2 increases expression EXP Sulindac results in increased expression of UBQLN2 mRNA CTD PMID:24136188 NCBI chr  X:18,723,313...18,726,732
Ensembl chr  X:18,723,341...18,726,732
JBrowse link
G Ufd1 ubiquitin recognition factor in ER associated degradation 1 decreases expression EXP Sulindac results in decreased expression of UFD1 mRNA CTD PMID:24136188 NCBI chr11:86,304,836...86,328,478
Ensembl chr11:86,304,815...86,328,469
JBrowse link
G Ufl1 Ufm1-specific ligase 1 increases expression EXP Sulindac results in increased expression of UFL1 mRNA CTD PMID:24136188 NCBI chr 5:39,616,479...39,650,894
Ensembl chr 5:39,615,956...39,650,895
JBrowse link
G Uggt2 UDP-glucose glycoprotein glucosyltransferase 2 increases expression ISO Sulindac results in increased expression of UGGT2 mRNA CTD PMID:11906190 NCBI chr15:104,235,678...104,405,308 JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 increases activity
increases glucuronidation
increases expression
ISO Sulindac results in increased activity of UGT1A1 protein
UGT1A1 protein results in increased glucuronidation of Sulindac
Sulindac results in increased expression of UGT1A1 mRNA
CTD PMID:15843492, PMID:17985343 NCBI chr 9:95,295,701...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2 increases glucuronidation ISO UGT1A3 protein results in increased glucuronidation of Sulindac CTD PMID:15843492 NCBI chr 9:95,285,592...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Ugt1a5 UDP glucuronosyltransferase family 1 member A5 increases glucuronidation ISO UGT1A4 protein results in increased glucuronidation of Sulindac CTD PMID:15843492 NCBI chr 9:95,256,628...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Ugt1a8 UDP glucuronosyltransferase family 1 member A8 increases glucuronidation ISO UGT1A8 protein results in increased glucuronidation of Sulindac CTD PMID:15843492 NCBI chr 9:95,221,474...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Ugt2b7 UDP glucuronosyltransferase family 2 member B7 increases glucuronidation ISO UGT2B7 protein results in increased glucuronidation of Sulindac CTD PMID:15843492 NCBI chr14:22,597,103...22,619,968 JBrowse link
G Ung uracil-DNA glycosylase decreases expression ISO Sulindac results in decreased expression of UNG mRNA CTD PMID:11906190 NCBI chr12:48,246,593...48,255,547
Ensembl chr12:48,246,569...48,254,822
JBrowse link
G Uqcc2 ubiquinol-cytochrome c reductase complex assembly factor 2 decreases expression EXP Sulindac results in decreased expression of UQCC2 mRNA CTD PMID:24136188 NCBI chr20:5,712,200...5,723,902
Ensembl chr20:5,712,203...5,723,902
JBrowse link
G Vapb VAMP associated protein B and C increases expression EXP Sulindac results in increased expression of VAPB mRNA CTD PMID:24136188 NCBI chr 3:171,832,558...171,871,042
Ensembl chr 3:171,832,500...171,868,647
JBrowse link
G Vash1 vasohibin 1 decreases expression EXP Sulindac results in decreased expression of VASH1 mRNA CTD PMID:24136188 NCBI chr 6:110,624,377...110,640,942
Ensembl chr 6:110,624,856...110,637,382
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions EXP [Sulindac co-treated with lipopolysaccharide, E coli O55-B5] affects the expression of VCAM1 mRNA CTD PMID:20371263 NCBI chr 2:219,071,193...219,090,931
Ensembl chr 2:219,071,193...219,097,619
JBrowse link
G Vcp valosin-containing protein decreases expression EXP Sulindac results in decreased expression of VCP mRNA CTD PMID:24136188 NCBI chr 5:58,426,548...58,445,953
Ensembl chr 5:58,426,549...58,445,953
JBrowse link
G Vps26b VPS26 retromer complex component B decreases expression EXP Sulindac results in decreased expression of VPS26B mRNA CTD PMID:24136188 NCBI chr 8:28,054,407...28,075,514
Ensembl chr 8:28,054,407...28,075,514
JBrowse link
G Vps26c VPS26 endosomal protein sorting factor C increases expression EXP Sulindac results in increased expression of VPS26C mRNA CTD PMID:24136188 NCBI chr11:34,764,053...34,792,446
Ensembl chr11:34,764,721...34,791,993
JBrowse link
G Vps29 VPS29 retromer complex component increases expression EXP Sulindac results in increased expression of VPS29 mRNA CTD PMID:24136188 NCBI chr12:39,690,069...39,699,114
Ensembl chr12:39,690,069...39,699,113
JBrowse link
G Vps35 VPS35 retromer complex component decreases expression EXP Sulindac results in decreased expression of VPS35 mRNA CTD PMID:24136188 NCBI chr19:27,464,937...27,500,636
Ensembl chr19:27,464,937...27,500,636
JBrowse link
G Vps53 VPS53 subunit of GARP complex increases expression EXP Sulindac results in increased expression of VPS53 mRNA CTD PMID:24136188 NCBI chr10:64,218,596...64,341,064
Ensembl chr10:64,222,276...64,341,109
JBrowse link
G Wdr3 WD repeat domain 3 increases expression ISO Sulindac results in increased expression of WDR3 mRNA CTD PMID:11906190 NCBI chr 2:202,447,749...202,470,398
Ensembl chr 2:202,447,745...202,470,399
JBrowse link
G Wdr61 WD repeat domain 61 decreases expression EXP Sulindac results in decreased expression of WDR61 mRNA CTD PMID:24136188 NCBI chr 8:59,296,339...59,313,663
Ensembl chr 8:59,296,346...59,313,574
JBrowse link
G Wdr83os WD repeat domain 83 opposite strand increases expression EXP Sulindac results in increased expression of WDR83OS mRNA CTD PMID:24136188 NCBI chr19:26,194,336...26,195,837
Ensembl chr19:26,194,465...26,195,837
JBrowse link
G Wwp1 WW domain containing E3 ubiquitin protein ligase 1 decreases expression EXP Sulindac results in decreased expression of WWP1 mRNA CTD PMID:24136188 NCBI chr 5:33,608,489...33,696,487
Ensembl chr 5:33,609,136...33,664,435
JBrowse link
G Xbp1 X-box binding protein 1 increases expression ISO Sulindac results in increased expression of XBP1 mRNA CTD PMID:11906190 NCBI chr14:85,753,736...85,758,820
Ensembl chr14:85,753,760...85,758,145
JBrowse link
G Xiap X-linked inhibitor of apoptosis multiple interactions ISO [Sulindac results in increased abundance of Reactive Oxygen Species] which results in decreased expression of XIAP protein CTD PMID:17136320 NCBI chr  X:128,409,425...128,455,786
Ensembl chr  X:128,409,472...128,453,000
JBrowse link
G Xpo1 exportin 1 multiple interactions EXP [Sulindac co-treated with lipopolysaccharide, E coli O55-B5] affects the expression of XPO1 mRNA CTD PMID:20371263 NCBI chr14:108,007,421...108,049,088
Ensembl chr14:108,007,724...108,049,660
JBrowse link
G Xpr1 xenotropic and polytropic retrovirus receptor 1 increases expression EXP Sulindac results in increased expression of XPR1 mRNA CTD PMID:24136188 NCBI chr13:72,918,552...73,056,785
Ensembl chr13:72,918,490...73,056,875
JBrowse link
G Xrcc5 X-ray repair cross complementing 5 decreases expression EXP Sulindac results in decreased expression of XRCC5 mRNA CTD PMID:24136188 NCBI chr 9:79,659,275...79,748,050
Ensembl chr 9:79,659,251...79,748,078
JBrowse link
G Yme1l1 YME1-like 1 ATPase decreases expression EXP Sulindac results in decreased expression of YME1L1 mRNA CTD PMID:24136188 NCBI chr17:89,701,899...89,741,919
Ensembl chr17:89,704,102...89,741,321
JBrowse link
G Ythdf3 YTH N(6)-methyladenosine RNA binding protein 3 increases expression EXP Sulindac results in increased expression of YTHDF3 mRNA CTD PMID:24136188 NCBI chr 2:100,677,388...100,711,365
Ensembl chr 2:100,677,411...100,710,417
JBrowse link
G Ywhab tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta increases expression EXP Sulindac results in increased expression of YWHAB mRNA CTD PMID:24136188 NCBI chr 3:160,391,108...160,399,931
Ensembl chr 3:160,391,106...160,399,931
JBrowse link
G Ywhae tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon increases expression EXP Sulindac results in increased expression of YWHAE mRNA CTD PMID:24136188 NCBI chr10:63,884,338...63,921,709
Ensembl chr10:63,884,338...63,921,709
JBrowse link
G Zc3h13 zinc finger CCCH type containing 13 increases expression EXP Sulindac results in increased expression of ZC3H13 mRNA CTD PMID:24136188 NCBI chr15:57,340,522...57,405,287
Ensembl chr15:57,340,579...57,405,287
JBrowse link
G Zfp106 zinc finger protein 106 decreases expression EXP Sulindac results in decreased expression of ZFP106 mRNA CTD PMID:24136188 NCBI chr 3:112,279,782...112,330,288
Ensembl chr 3:112,283,112...112,320,762
JBrowse link
G Zfp148 zinc finger protein 148 decreases expression EXP Sulindac results in decreased expression of ZFP148 mRNA CTD PMID:24136188 NCBI chr11:70,509,909...70,618,422
Ensembl chr11:70,514,750...70,618,347
JBrowse link
G Zfp281 zinc finger protein 281 increases expression EXP Sulindac results in increased expression of ZFP281 mRNA CTD PMID:24136188 NCBI chr13:53,531,080...53,534,399
Ensembl chr13:53,506,925...53,534,353
JBrowse link
G Zfp354a zinc finger protein 354A increases expression ISO Sulindac results in increased expression of ZNF354A mRNA CTD PMID:11906190 NCBI chr10:36,586,495...36,600,172
Ensembl chr10:36,589,181...36,600,469
JBrowse link
G Zfp423 zinc finger protein 423 decreases expression EXP Sulindac results in decreased expression of ZFP423 mRNA CTD PMID:24136188 NCBI chr19:20,147,201...20,405,999
Ensembl chr19:20,147,037...20,406,003
JBrowse link
G Znhit1 zinc finger, HIT-type containing 1 increases expression EXP Sulindac results in increased expression of ZNHIT1 mRNA CTD PMID:24136188 NCBI chr12:22,726,643...22,732,917
Ensembl chr12:22,726,643...22,732,943
JBrowse link
G Znhit3 zinc finger, HIT-type containing 3 increases expression EXP Sulindac results in increased expression of ZNHIT3 mRNA CTD PMID:24136188 NCBI chr10:72,227,710...72,235,932
Ensembl chr10:72,228,222...72,235,888
JBrowse link
sulindac sulfide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcg2 ATP binding cassette subfamily G member 2 increases expression ISO sulindac sulfide results in increased expression of ABCG2 mRNA CTD PMID:16184548 NCBI chr 4:88,765,441...88,890,268
Ensembl chr 4:88,832,178...88,890,621
JBrowse link
G Actn1 actinin, alpha 1 decreases expression ISO sulindac sulfide results in decreased expression of ACTN1 mRNA CTD PMID:16184548 NCBI chr 6:103,376,557...103,470,497
Ensembl chr 6:103,375,799...103,470,555
JBrowse link
G Adam9 ADAM metallopeptidase domain 9 decreases expression ISO sulindac sulfide results in decreased expression of ADAM9 mRNA CTD PMID:16184548 NCBI chr16:71,810,377...71,887,926
Ensembl chr16:71,810,377...71,887,926
JBrowse link
G Adm adrenomedullin increases expression ISO sulindac sulfide results in increased expression of ADM mRNA CTD PMID:16184548 NCBI chr 1:175,443,189...175,447,260
Ensembl chr 1:175,445,088...175,447,259
JBrowse link
G Adra2c adrenoceptor alpha 2C decreases expression ISO sulindac sulfide results in decreased expression of ADRA2C mRNA CTD PMID:12734198 NCBI chr14:80,730,307...80,732,010
Ensembl chr14:80,730,307...80,732,010
JBrowse link
G Ahr aryl hydrocarbon receptor increases localization ISO sulindac sulfide results in increased localization of AHR protein CTD PMID:17985343 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Akap12 A-kinase anchoring protein 12 increases expression ISO sulindac sulfide results in increased expression of AKAP12 mRNA CTD PMID:12734198 NCBI chr 1:40,816,130...40,906,582
Ensembl chr 1:40,816,107...40,906,581
JBrowse link
G Aldoc aldolase, fructose-bisphosphate C decreases expression ISO sulindac sulfide results in decreased expression of ALDOC mRNA CTD PMID:16184548 NCBI chr10:65,586,504...65,590,093
Ensembl chr10:65,586,504...65,590,126
JBrowse link
G Alox15 arachidonate 15-lipoxygenase increases expression ISO sulindac sulfide results in increased expression of ALOX15 protein CTD PMID:16166323 NCBI chr10:56,953,692...56,962,145
Ensembl chr10:56,953,691...56,962,161
JBrowse link
G Anxa5 annexin A5 increases expression ISO sulindac sulfide results in increased expression of ANXA5 protein CTD PMID:18678619 NCBI chr 2:123,162,477...123,194,730
Ensembl chr 2:123,162,461...123,193,130
JBrowse link
G Apoa1 apolipoprotein A1 multiple interactions ISO sulindac sulfide inhibits the reaction [Phosphatidylinositols results in increased expression of APOA1 protein] CTD PMID:19013290 NCBI chr 8:50,525,091...50,526,875
Ensembl chr 8:50,525,091...50,526,875
JBrowse link
G App amyloid beta precursor protein multiple interactions
affects cleavage
ISO
EXP
[sulindac sulfide results in decreased activity of PSEN1 protein] which affects the cleavage of APP protein; PSEN1 protein affects the reaction [sulindac sulfide affects the cleavage of APP protein]; PSEN1 protein mutant form promotes the reaction [sulindac sulfide affects the cleavage of APP protein]; sulindac sulfide affects the cleavage of and affects the localization of APP protein; sulindac sulfide affects the reaction [PSEN1 protein affects the cleavage of APP protein]
sulindac sulfide inhibits the reaction [APP protein results in increased uptake of Calcium]
CTD PMID:11700559, PMID:12637581, PMID:12777371, PMID:12805356, PMID:14690522, PMID:15274632, PMID:17573346, PMID:17962197, PMID:18359496, PMID:18426795, PMID:18648507 NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858
JBrowse link
G Ar androgen receptor multiple interactions ISO AR protein affects the reaction [sulindac sulfide results in decreased expression of KLK3 protein]; sulindac sulfide results in decreased expression of and results in decreased activity of AR protein CTD PMID:14581372 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Areg amphiregulin increases expression ISO sulindac sulfide results in increased expression of AREG mRNA CTD PMID:16184548 NCBI chr14:18,521,921...18,531,179
Ensembl chr14:18,521,930...18,531,179
JBrowse link
G Arl6ip1 ADP-ribosylation factor like GTPase 6 interacting protein 1 decreases expression ISO sulindac sulfide results in decreased expression of ARL6IP1 mRNA CTD PMID:12734198 NCBI chr 1:187,770,160...187,779,675
Ensembl chr 1:187,770,160...187,779,675
JBrowse link
G Arpc1b actin related protein 2/3 complex, subunit 1B decreases expression ISO sulindac sulfide results in decreased expression of ARPC1B mRNA CTD PMID:12734198 NCBI chr12:11,252,300...11,265,849
Ensembl chr12:11,252,296...11,265,865
JBrowse link
G Asah1 N-acylsphingosine amidohydrolase 1 decreases expression ISO sulindac sulfide results in decreased expression of ASAH1 mRNA CTD PMID:16184548 NCBI chr16:53,998,604...54,030,006
Ensembl chr16:53,998,560...54,040,836
JBrowse link
G Atf3 activating transcription factor 3 multiple interactions
increases expression
ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [sulindac sulfide results in increased expression of ATF3 mRNA]; [sulindac sulfide results in increased phosphorylation of MAPK1 protein] which results in increased expression of ATF3 protein; [sulindac sulfide results in increased phosphorylation of MAPK3 protein] which results in increased expression of ATF3 protein; EGR1 protein promotes the reaction [sulindac sulfide results in increased expression of ATF3 mRNA]; MAP2K1 protein promotes the reaction [sulindac sulfide results in increased expression of ATF3 mRNA]
sulindac sulfide results in increased expression of ATF3 mRNA; sulindac sulfide results in increased expression of ATF3 protein
CTD PMID:12734198, PMID:15897233, PMID:16079301, PMID:16184548, PMID:21554132, PMID:24440808 NCBI chr13:109,817,892...109,849,632
Ensembl chr13:109,817,728...109,849,632
JBrowse link
G Atp6v0a1 ATPase H+ transporting V0 subunit a1 increases expression ISO sulindac sulfide results in increased expression of ATP6V0A1 mRNA CTD PMID:16184548 NCBI chr10:88,914,264...88,967,736
Ensembl chr10:88,914,276...88,967,748
JBrowse link
G Aurka aurora kinase A decreases expression ISO sulindac sulfide results in decreased expression of AURKA mRNA CTD PMID:12734198 NCBI chr 3:170,364,177...170,380,278
Ensembl chr 3:170,364,181...170,378,210
JBrowse link
G Bad BCL2-associated agonist of cell death decreases expression
increases localization
multiple interactions
ISO sulindac sulfide results in decreased expression of BAD protein
sulindac sulfide results in increased localization of BAD protein
[sulindac sulfide results in decreased expression of YWHAE protein] which results in increased localization of BAD protein; sulindac sulfide promotes the reaction [BAD protein binds to YWHAE protein]
CTD PMID:17409426, PMID:18678619 NCBI chr 1:222,198,516...222,207,459
Ensembl chr 1:222,198,534...222,207,453
JBrowse link
G Bak1 BCL2-antagonist/killer 1 increases response to substance EXP BAK1 results in increased susceptibility to sulindac sulfide CTD PMID:18349538 NCBI chr20:5,609,620...5,618,899
Ensembl chr20:5,609,625...5,618,260
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions
increases expression
decreases expression
affects response to substance
ISO BAX protein affects the reaction [TNFSF10 protein promotes the reaction [sulindac sulfide results in increased cleavage of and results in increased activity of CASP3 protein]]; BAX protein affects the reaction [TNFSF10 protein promotes the reaction [sulindac sulfide results in increased cleavage of and results in increased activity of CASP8 protein]]; BAX protein affects the reaction [TNFSF10 protein promotes the reaction [sulindac sulfide results in increased cleavage of and results in increased activity of CASP9 protein]]
sulindac sulfide results in increased expression of BAX mRNA
sulindac sulfide results in decreased expression of BAX protein
BAX protein affects the susceptibility to sulindac sulfide
CTD PMID:12203115, PMID:16886631 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcam basal cell adhesion molecule (Lutheran blood group) decreases expression ISO sulindac sulfide results in decreased expression of BCAM mRNA CTD PMID:12734198 NCBI chr 1:80,674,463...80,689,122
Ensembl chr 1:80,674,444...80,689,171
JBrowse link
G Bcar1 BCAR1 scaffold protein, Cas family member decreases phosphorylation ISO sulindac sulfide results in decreased phosphorylation of BCAR1 protein CTD PMID:10741720 NCBI chr19:43,932,543...43,967,452
Ensembl chr19:43,932,554...43,955,783
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO sulindac sulfide results in decreased expression of BCL2 protein CTD PMID:18678619 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bcl2l1 Bcl2-like 1 decreases expression ISO sulindac sulfide results in decreased expression of BCL2L1 protein CTD PMID:11912124 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
JBrowse link
G Bid BH3 interacting domain death agonist decreases expression
increases cleavage
ISO sulindac sulfide results in decreased expression of BID protein
sulindac sulfide results in increased cleavage of BID protein
CTD PMID:12203115, PMID:16886631 NCBI chr 4:153,439,812...153,465,247
Ensembl chr 4:153,442,218...153,465,203
JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 increases expression ISO sulindac sulfide results in increased expression of BIRC3 mRNA CTD PMID:16184548 NCBI chr 8:6,048,590...6,076,828
Ensembl chr 8:6,048,969...6,076,598
JBrowse link
G Bub1b BUB1 mitotic checkpoint serine/threonine kinase B decreases expression ISO sulindac sulfide results in decreased expression of BUB1B mRNA CTD PMID:16184548 NCBI chr 3:110,367,949...110,420,471
Ensembl chr 3:110,367,939...110,420,458
JBrowse link
G Cacng3 calcium voltage-gated channel auxiliary subunit gamma 3 increases expression ISO sulindac sulfide results in increased expression of CACNG3 mRNA CTD PMID:16184548 NCBI chr 1:192,613,766...192,708,371
Ensembl chr 1:192,613,372...192,709,078
JBrowse link
G Casp3 caspase 3 increases activity
increases expression
multiple interactions
ISO sulindac sulfide results in increased activity of CASP3 protein
sulindac sulfide results in increased expression of CASP3 mRNA
[sulindac sulfide co-treated with TNF protein] results in increased activity of CASP3 protein; BAX protein affects the reaction [TNFSF10 protein promotes the reaction [sulindac sulfide results in increased cleavage of and results in increased activity of CASP3 protein]]; MAP2K1 protein inhibits the reaction [sulindac sulfide results in increased cleavage of and results in increased activity of CASP3 protein]; PTGS2 protein inhibits the reaction [sulindac sulfide results in increased activity of CASP3 protein]; sulindac sulfide results in increased cleavage of and results in increased activity of CASP3 protein; tempol inhibits the reaction [[sulindac sulfide co-treated with TNF protein] results in increased activity of CASP3 protein]; TNFSF10 protein promotes the reaction [sulindac sulfide results in increased cleavage of and results in increased activity of CASP3 protein]
CTD PMID:11051267, PMID:12203115, PMID:12414664, PMID:14555707, PMID:15548677, PMID:16886631, PMID:20371263 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp7 caspase 7 multiple interactions ISO [sulindac sulfide co-treated with TNF protein] results in increased activity of CASP7 protein; tempol inhibits the reaction [[sulindac sulfide co-treated with TNF protein] results in increased activity of CASP7 protein] CTD PMID:20371263 NCBI chr 1:277,190,557...277,242,779
Ensembl chr 1:277,190,964...277,242,774
JBrowse link
G Casp8 caspase 8 multiple interactions
increases activity
ISO BAX protein affects the reaction [TNFSF10 protein promotes the reaction [sulindac sulfide results in increased cleavage of and results in increased activity of CASP8 protein]]; PTGS2 protein inhibits the reaction [sulindac sulfide results in increased activity of CASP8 protein]; sulindac sulfide results in increased cleavage of and results in increased activity of CASP8 protein; TNFSF10 protein promotes the reaction [sulindac sulfide results in increased cleavage of and results in increased activity of CASP8 protein] CTD PMID:11559570, PMID:12203115, PMID:12414664, PMID:16886631 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Casp9 caspase 9 multiple interactions
increases activity
ISO BAX protein affects the reaction [TNFSF10 protein promotes the reaction [sulindac sulfide results in increased cleavage of and results in increased activity of CASP9 protein]]; PTGS2 protein inhibits the reaction [sulindac sulfide results in increased activity of CASP9 protein]; sulindac sulfide results in increased cleavage of and results in increased activity of CASP9 protein; TNFSF10 protein promotes the reaction [sulindac sulfide results in increased cleavage of and results in increased activity of CASP9 protein] CTD PMID:12203115, PMID:12414664 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Ccar1 cell division cycle and apoptosis regulator 1 increases expression ISO sulindac sulfide results in increased expression of CCAR1 mRNA CTD PMID:12734198 NCBI chr20:32,373,443...32,416,044
Ensembl chr20:32,373,443...32,416,044
JBrowse link
G Ccn2 cellular communication network factor 2 decreases expression
increases expression
ISO sulindac sulfide results in decreased expression of CCN2 mRNA
sulindac sulfide results in increased expression of CCN2 mRNA
CTD PMID:12734198, PMID:16184548 NCBI chr 1:21,851,657...21,854,773
Ensembl chr 1:21,851,660...21,854,773
JBrowse link
G Ccnd1 cyclin D1 multiple interactions
decreases expression
ISO sulindac sulfide inhibits the reaction [CTNNB1 protein results in increased expression of CCND1 protein]
sulindac sulfide results in decreased expression of CCND1 mRNA; sulindac sulfide results in decreased expression of CCND1 protein
CTD PMID:14710233, PMID:15188006, PMID:15767558 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Cd4 Cd4 molecule increases expression ISO sulindac sulfide results in increased expression of CD4 mRNA CTD PMID:12734198 NCBI chr 4:157,381,862...157,408,357
Ensembl chr 4:157,383,052...157,408,176
JBrowse link
G Cd46 CD46 molecule decreases expression ISO sulindac sulfide results in decreased expression of CD46 mRNA CTD PMID:16184548 NCBI chr13:113,786,525...113,818,741
Ensembl chr13:113,787,349...113,817,995
JBrowse link
G Cdh1 cadherin 1 multiple interactions ISO sulindac sulfide results in increased expression of and results in increased activity of CDH1 protein CTD PMID:12391285 NCBI chr19:38,768,467...38,838,395
Ensembl chr19:38,768,467...38,838,395
JBrowse link
G Cdh17 cadherin 17 decreases expression ISO sulindac sulfide results in decreased expression of CDH17 mRNA CTD PMID:16184548 NCBI chr 5:25,354,187...25,443,675
Ensembl chr 5:25,391,115...25,443,718
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions
affects activity
increases expression
ISO PPARD protein inhibits the reaction [sulindac sulfide results in increased expression of CDKN1A mRNA]; PPARG protein promotes the reaction [sulindac sulfide results in increased expression of CDKN1A mRNA]
sulindac sulfide affects the activity of CDKN1A protein
sulindac sulfide results in increased expression of CDKN1A mRNA; sulindac sulfide results in increased expression of CDKN1A protein
CTD PMID:15694660, PMID:15767558, PMID:16091736, PMID:16184548 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta increases expression ISO sulindac sulfide results in increased expression of CEBPB mRNA; sulindac sulfide results in increased expression of CEBPB protein CTD PMID:12734198, PMID:16184548 NCBI chr 3:164,424,502...164,425,933
Ensembl chr 3:164,424,515...164,425,910
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator decreases expression ISO sulindac sulfide results in decreased expression of CFLAR protein CTD PMID:11912124 NCBI chr 9:65,534,608...65,586,395
Ensembl chr 9:65,534,704...65,587,251
JBrowse link
G Clp1 cleavage factor polyribonucleotide kinase subunit 1 decreases expression ISO sulindac sulfide results in decreased expression of CLP1 mRNA CTD PMID:12734198 NCBI chr 3:72,125,269...72,137,122
Ensembl chr 3:72,125,273...72,128,973
JBrowse link
G Cryab crystallin, alpha B increases expression ISO sulindac sulfide results in increased expression of CRYAB mRNA CTD PMID:16184548 NCBI chr 8:55,178,543...55,182,546
Ensembl chr 8:55,178,289...55,182,545
JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions
decreases expression
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [sulindac sulfide results in decreased expression of CTNNB1 protein]; sulindac sulfide affects the localization of and results in decreased expression of CTNNB1 protein; sulindac sulfide inhibits the reaction [CTNNB1 protein results in increased expression of CCND1 protein]; sulindac sulfide inhibits the reaction [CTNNB1 protein results in increased expression of MET protein]; sulindac sulfide results in decreased expression of and results in decreased localization of CTNNB1 protein CTD PMID:14555707, PMID:14710233, PMID:15188006 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372
JBrowse link
G Ctsc cathepsin C decreases expression ISO sulindac sulfide results in decreased expression of CTSC mRNA CTD PMID:16184548 NCBI chr 1:151,918,514...151,949,979
Ensembl chr 1:151,918,571...151,949,983
JBrowse link
G Cyb5b cytochrome b5 type B decreases expression ISO sulindac sulfide results in decreased expression of CYB5B mRNA CTD PMID:12734198 NCBI chr19:39,357,814...39,391,680
Ensembl chr19:39,357,791...39,393,189
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression ISO sulindac sulfide results in increased expression of CYP1A1 mRNA CTD PMID:12734198, PMID:16184548, PMID:17985343 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression ISO sulindac sulfide results in increased expression of CYP1A2 mRNA CTD PMID:17985343 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 increases expression ISO sulindac sulfide results in increased expression of CYP1B1 mRNA CTD PMID:12734198, PMID:17985343 NCBI chr 6:2,308,179...2,316,739
Ensembl chr 6:2,307,808...2,316,722
JBrowse link
G Dcbld2 discoidin, CUB and LCCL domain containing 2 increases expression ISO sulindac sulfide results in increased expression of DCBLD2 mRNA CTD PMID:12734198 NCBI chr11:44,237,814...44,292,884
Ensembl chr11:44,241,111...44,292,884
JBrowse link
G Ddx11 DEAD/H-box helicase 11 decreases expression ISO sulindac sulfide results in decreased expression of DDX11 mRNA CTD PMID:16184548 NCBI chr 9:114,113,642...114,133,908
Ensembl chr 9:114,111,580...114,132,492
JBrowse link
G Dhcr24 24-dehydrocholesterol reductase decreases expression ISO sulindac sulfide results in decreased expression of DHCR24 mRNA CTD PMID:16184548 NCBI chr 5:126,164,708...126,188,926
Ensembl chr 5:126,164,674...126,191,206
JBrowse link
G Dhcr7 7-dehydrocholesterol reductase decreases expression ISO sulindac sulfide results in decreased expression of DHCR7 mRNA CTD PMID:16184548 NCBI chr 1:217,018,916...217,034,890
Ensembl chr 1:217,018,916...217,034,904
JBrowse link
G Dynll1 dynein light chain LC8-type 1 decreases expression ISO sulindac sulfide results in decreased expression of DYNLL1 mRNA CTD PMID:12734198 NCBI chr12:47,074,200...47,076,573
Ensembl chr12:47,074,200...47,076,572
JBrowse link
G Egfr epidermal growth factor receptor multiple interactions
decreases expression
increases ubiquitination
increases phosphorylation
decreases phosphorylation
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [sulindac sulfide results in decreased expression of EGFR protein]; Chloroquine inhibits the reaction [sulindac sulfide results in decreased expression of EGFR protein]
sulindac sulfide results in increased ubiquitination of EGFR protein
sulindac sulfide results in increased phosphorylation of EGFR protein
sulindac sulfide results in decreased phosphorylation of EGFR protein
CTD PMID:20332299 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796
JBrowse link
G Egr1 early growth response 1 multiple interactions
increases expression
ISO EGR1 protein affects the reaction [sulindac sulfide results in increased expression of THBS1 mRNA]; EGR1 protein promotes the reaction [sulindac sulfide results in increased expression of ATF3 mRNA]; EGR1 protein promotes the reaction [sulindac sulfide results in increased expression of GDF15 mRNA]; ELK1 protein promotes the reaction [sulindac sulfide results in increased expression of EGR1 mRNA]; MAPK1 protein promotes the reaction [sulindac sulfide results in increased expression of EGR1 mRNA]; MAPK3 protein promotes the reaction [sulindac sulfide results in increased expression of EGR1 mRNA]; U 0126 inhibits the reaction [sulindac sulfide results in increased expression of EGR1 mRNA]
sulindac sulfide results in increased expression of EGR1 mRNA; sulindac sulfide results in increased expression of EGR1 protein
CTD PMID:15509713, PMID:16079301, PMID:16227405, PMID:17599376 NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429
JBrowse link
G Elk1 ETS transcription factor ELK1 multiple interactions ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [sulindac sulfide results in increased phosphorylation of and results in increased activity of ELK1 protein]; ELK1 protein promotes the reaction [sulindac sulfide results in increased expression of EGR1 mRNA]; MAPK1 protein promotes the reaction [sulindac sulfide results in increased phosphorylation of and results in increased activity of ELK1 protein]; MAPK3 protein promotes the reaction [sulindac sulfide results in increased phosphorylation of and results in increased activity of ELK1 protein]; sulindac sulfide results in increased phosphorylation of and affects the activity of ELK1 protein; U 0126 inhibits the reaction [sulindac sulfide results in increased phosphorylation of and results in increased activity of ELK1 protein] CTD PMID:17599376 NCBI chr  X:1,287,875...1,304,822
Ensembl chr  X:1,297,099...1,304,822
JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 multiple interactions
decreases expression
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [sulindac sulfide results in decreased expression of ERBB2 protein] CTD PMID:20332299 NCBI chr10:86,367,596...86,391,728
Ensembl chr10:86,367,596...86,391,728
JBrowse link
G Erbb3 erb-b2 receptor tyrosine kinase 3 multiple interactions
decreases expression
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [sulindac sulfide results in decreased expression of ERBB3 protein] CTD PMID:20332299 NCBI chr 7:2,989,202...3,010,610
Ensembl chr 7:2,989,340...3,010,350
JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 affects cleavage ISO sulindac sulfide affects the cleavage of ERBB4 protein CTD PMID:12777371 NCBI chr 9:75,021,790...76,178,936
Ensembl chr 9:75,021,790...75,528,644
JBrowse link
G Esd esterase D increases expression ISO sulindac sulfide results in increased expression of ESD mRNA CTD PMID:12734198 NCBI chr15:56,756,848...56,776,348
Ensembl chr15:56,756,661...56,776,348
JBrowse link
G Esr1 estrogen receptor 1 decreases expression ISO sulindac sulfide results in decreased expression of ESR1 mRNA; sulindac sulfide results in decreased expression of ESR1 protein CTD PMID:16740773 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Etfb electron transfer flavoprotein subunit beta decreases expression ISO sulindac sulfide results in decreased expression of ETFB mRNA CTD PMID:16184548 NCBI chr 1:98,472,776...98,486,940
Ensembl chr 1:98,472,745...98,486,976
JBrowse link
G Etnppl ethanolamine-phosphate phospho-lyase increases expression ISO sulindac sulfide results in increased expression of ETNPPL mRNA CTD PMID:12734198 NCBI chr 2:235,738,377...235,760,351
Ensembl chr 2:235,738,416...235,760,352
JBrowse link
G Fabp1 fatty acid binding protein 1 multiple interactions
increases expression
ISO 2-chloro-5-nitrobenzanilide inhibits the reaction [sulindac sulfide analog results in increased expression of FABP1 protein]; PPARG protein affects the reaction [sulindac sulfide analog results in increased expression of FABP1 protein] CTD PMID:17602619, PMID:18665581 NCBI chr 4:99,063,181...99,066,957
Ensembl chr 4:99,063,181...99,066,954
JBrowse link
G Fabp4 fatty acid binding protein 4 multiple interactions
increases expression
ISO 2-chloro-5-nitrobenzanilide inhibits the reaction [sulindac sulfide analog results in increased expression of FABP4 protein]; PPARG protein affects the reaction [sulindac sulfide analog results in increased expression of FABP4 protein] CTD PMID:17602619, PMID:18665581 NCBI chr 2:93,792,666...93,797,267
Ensembl chr 2:93,792,601...93,797,305
JBrowse link
G Fcgrt Fc fragment of IgG receptor and transporter decreases expression ISO sulindac sulfide results in decreased expression of FCGRT mRNA CTD PMID:16184548 NCBI chr 1:101,086,872...101,096,159
Ensembl chr 1:101,086,877...101,095,594
JBrowse link
G Fdps farnesyl diphosphate synthase decreases expression ISO sulindac sulfide results in decreased expression of FDPS mRNA CTD PMID:16184548 NCBI chr 2:188,403,595...188,413,219
Ensembl chr 2:188,392,858...188,413,219
JBrowse link
G Fgfr4 fibroblast growth factor receptor 4 decreases expression ISO sulindac sulfide results in decreased expression of FGFR4 mRNA CTD PMID:16184548 NCBI chr17:9,990,072...10,004,339
Ensembl chr17:9,990,078...10,004,321
JBrowse link
G Fmo3 flavin containing dimethylaniline monoxygenase 3 affects metabolic processing
increases metabolic processing
ISO FMO3 gene polymorphism affects the metabolism of sulindac sulfide
FMO3 protein results in increased metabolism of sulindac sulfide
CTD PMID:17142560, PMID:17559352 NCBI chr13:80,837,418...80,856,214
Ensembl chr13:80,837,420...80,862,963
JBrowse link
G Foxm1 forkhead box M1 decreases expression ISO sulindac sulfide results in decreased expression of FOXM1 mRNA CTD PMID:16184548 NCBI chr 4:161,685,236...161,697,633
Ensembl chr 4:161,685,258...161,696,305
JBrowse link
G Gal3st4 galactose-3-O-sulfotransferase 4 decreases expression ISO sulindac sulfide results in decreased expression of GAL3ST4 mRNA CTD PMID:16184548 NCBI chr12:19,583,110...19,592,444
Ensembl chr12:19,583,110...19,592,000
JBrowse link
G Gars glycyl-tRNA synthetase increases expression ISO sulindac sulfide results in increased expression of GARS1 mRNA CTD PMID:12734198 NCBI chr 4:85,235,122...85,276,085
Ensembl chr 4:85,235,172...85,276,044
JBrowse link
G Gdf15 growth differentiation factor 15 multiple interactions
increases expression
ISO EGR1 protein promotes the reaction [sulindac sulfide results in increased expression of GDF15 mRNA]
sulindac sulfide results in increased expression of GDF15 mRNA; sulindac sulfide results in increased expression of GDF15 protein
CTD PMID:11895857, PMID:11925476, PMID:12734198, PMID:15180942, PMID:15509713, PMID:15555568, PMID:15767558, PMID:18076062 NCBI chr16:20,555,395...20,557,978
Ensembl chr16:20,555,395...20,557,978
JBrowse link
G Gk glycerol kinase increases expression ISO sulindac sulfide results in increased expression of GK mRNA CTD PMID:16184548 NCBI chr  X:54,227,291...54,303,897
Ensembl chr  X:54,227,397...54,303,864
JBrowse link
G Glcci1 glucocorticoid induced 1 increases expression ISO sulindac sulfide results in increased expression of GLCCI1 mRNA CTD PMID:16184548 NCBI chr 4:34,282,625...34,612,709
Ensembl chr 4:34,282,625...34,614,438
JBrowse link
G Grn granulin precursor decreases expression ISO sulindac sulfide results in decreased expression of GRN mRNA CTD PMID:16184548 NCBI chr10:90,377,103...90,383,207
Ensembl chr10:90,376,933...90,383,205
JBrowse link
G Gstp1 glutathione S-transferase pi 1 multiple interactions ISO sulindac sulfide binds to and results in decreased activity of GSTP1 protein CTD PMID:15300575 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
JBrowse link
G Hdac1 histone deacetylase 1 decreases expression ISO sulindac sulfide results in decreased expression of HDAC1 mRNA CTD PMID:16184548 NCBI chr 5:147,716,664...147,743,723
Ensembl chr 5:147,716,664...147,743,723
JBrowse link
G Hgf hepatocyte growth factor decreases expression ISO sulindac sulfide results in decreased expression of HGF mRNA CTD PMID:10807402 NCBI chr 4:15,435,460...15,505,377
Ensembl chr 4:15,433,295...15,505,362
JBrowse link
G Hm13 histocompatibility minor 13 affects binding
multiple interactions
ISO sulindac sulfide binds to HM13 protein
sulindac sulfide inhibits the reaction [L 685458 binds to HM13 protein]
CTD PMID:17932033 NCBI chr 3:148,150,695...148,189,623
Ensembl chr 3:148,150,698...148,189,623
JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 decreases expression ISO sulindac sulfide results in decreased expression of HSD3B1 mRNA CTD PMID:16184548
G Hspa1b heat shock protein family A (Hsp70) member 1B increases expression ISO sulindac sulfide results in increased expression of HSPA1B mRNA CTD PMID:16184548 NCBI chr20:4,877,638...4,880,112
Ensembl chr20:2,699,712...2,701,815
JBrowse link
G Icam2 intercellular adhesion molecule 2 increases expression ISO sulindac sulfide results in increased expression of ICAM2 mRNA CTD PMID:16184548 NCBI chr10:94,569,889...94,581,218
Ensembl chr10:94,569,890...94,576,512
JBrowse link
G Id1 inhibitor of DNA binding 1, HLH protein decreases expression ISO sulindac sulfide results in decreased expression of ID1 mRNA; sulindac sulfide results in decreased expression of ID1 protein CTD PMID:16184548, PMID:21554132 NCBI chr 3:148,214,623...148,216,715
Ensembl chr 3:148,215,540...148,216,718
JBrowse link
G Ifitm3 interferon induced transmembrane protein 3 decreases expression ISO sulindac sulfide results in decreased expression of IFITM3 mRNA CTD PMID:16184548 NCBI chr 1:213,810,712...213,811,821
Ensembl chr 1:213,810,696...213,811,901
JBrowse link
G Ifrd1 interferon-related developmental regulator 1 increases expression ISO sulindac sulfide results in increased expression of IFRD1 mRNA CTD PMID:12734198 NCBI chr 6:60,132,025...60,151,354
Ensembl chr 6:60,132,024...60,151,420
JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta decreases activity ISO sulindac sulfide results in decreased activity of IKBKB protein CTD PMID:11912124 NCBI chr16:74,177,233...74,230,809
Ensembl chr16:74,177,215...74,230,815
JBrowse link
G Il13ra1 interleukin 13 receptor subunit alpha 1 decreases expression ISO sulindac sulfide results in decreased expression of IL13RA1 mRNA CTD PMID:16184548 NCBI chr  X:122,724,081...122,783,801
Ensembl chr  X:122,724,129...122,781,479
JBrowse link
G Il1r1 interleukin 1 receptor type 1 increases expression ISO sulindac sulfide results in increased expression of IL1R1 mRNA CTD PMID:16184548 NCBI chr 9:46,962,291...47,038,139
Ensembl chr 9:46,962,288...47,036,670