Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) RatMine GViewer (Genome Viewer) Overgo Probe Designer ACP Haplotyper Genome Scanner
Aging & Age-Related Disease Cancer Cardiovascular Disease COVID-19 Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models PhenoMiner (Quantitative Phenotypes) Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes GERRC (Gene Editing Rat Resource Center) Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Poster Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:sodium nitrite
go back to main search page
Accession:CHEBI:78870 term browser browse the term
Definition:An inorganic sodium salt having nitrite as the counterion. Used as a food preservative and antidote to cyanide poisoning.
Synonyms:related_synonym: Formula=NNaO2;   InChI=1S/HNO2.Na/c2-1-3;/h(H,2,3);/q;+1/p-1;   InChIKey=LPXPTNMVRIOKMN-UHFFFAOYSA-M;   NaNO2;   Natrium nitrit;   Nitrite de sodium;   Nitrito sodico;   SMILES=[Na+].[O-]N=O
 xref: CAS:7632-00-0;   KEGG:D05865
 xref_mesh: MESH:D012977
 xref: PMID:24200576;   PMID:24266433;   PMID:24333935;   PMID:24363302;   PMID:24535441;   PMID:24639423;   PMID:24658348;   PMID:24834717;   PMID:24861891;   PMID:24878382;   PMID:24898570;   PMID:24929713;   Reaxys:906771;   Wikipedia:Sodium_nitrite

show annotations for term's descendants           Sort by:
 
sodium nitrite term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase multiple interactions
decreases activity		 ISO [Hypochlorous Acid co-treated with Sodium Nitrite] results in decreased activity of ACHE protein
Sodium Nitrite results in decreased activity of ACHE protein		 CTD PMID:12414318 PMID:26231821 NCBI chr12:22,472,358...22,477,052
Ensembl chr12:22,472,358...22,478,753 		JBrowse link
G Acp1 acid phosphatase 1 increases activity ISO Sodium Nitrite results in increased activity of ACP1 protein CTD PMID:26231821 NCBI chr 6:49,836,064...49,851,714
Ensembl chr 6:49,836,075...49,851,714 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 increases expression
multiple interactions		 EXP Sodium Nitrite results in increased expression of AKT1 protein
Carnosine inhibits the reaction [Sodium Nitrite results in increased expression of AKT1 protein]		 CTD PMID:28266762 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258 		JBrowse link
G Ampd3 adenosine monophosphate deaminase 3 increases activity ISO Sodium Nitrite results in increased activity of AMPD3 protein CTD PMID:26231821 NCBI chr 1:175,585,301...175,630,479
Ensembl chr 1:175,586,097...175,630,467 		JBrowse link
G App amyloid beta precursor protein multiple interactions ISO [Hydrogen Peroxide co-treated with Sodium Nitrite] promotes the reaction [APP protein modified form binds to Heme] CTD PMID:25211009 NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression
multiple interactions		 EXP Sodium Nitrite results in increased expression of BAX mRNA; Sodium Nitrite results in increased expression of BAX protein
Carnosine inhibits the reaction [Sodium Nitrite results in increased expression of BAX mRNA]; Carnosine inhibits the reaction [Sodium Nitrite results in increased expression of BAX protein]; Quercetin inhibits the reaction [Sodium Nitrite results in increased expression of BAX protein]		 CTD PMID:28000380 PMID:28266762 PMID:28833918 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207 		JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression
multiple interactions		 EXP Sodium Nitrite results in decreased expression of BCL2 mRNA; Sodium Nitrite results in decreased expression of BCL2 protein
Carnosine inhibits the reaction [Sodium Nitrite results in decreased expression of BCL2 protein]; Quercetin inhibits the reaction [Sodium Nitrite results in decreased expression of BCL2 protein]		 CTD PMID:28000380 PMID:28266762 PMID:28833918 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374 		JBrowse link
G Casp3 caspase 3 increases activity
multiple interactions		 EXP Sodium Nitrite results in increased activity of CASP3 protein
Carnosine inhibits the reaction [Sodium Nitrite results in increased activity of CASP3 protein]		 CTD PMID:28833918 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204 		JBrowse link
G Cat catalase decreases activity
increases activity		 ISO Sodium Nitrite results in decreased activity of CAT protein
Sodium Nitrite results in increased activity of CAT protein		 CTD PMID:26231821 PMID:31476334 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058 		JBrowse link
G Ccnb1 cyclin B1 increases expression ISO Sodium Nitrite results in increased expression of CCNB1 protein CTD PMID:20025956 NCBI chr 2:30,782,133...30,791,106
Ensembl chr 2:30,783,915...30,791,221 		JBrowse link
G Chek1 checkpoint kinase 1 increases expression ISO Sodium Nitrite results in increased expression of CHEK1 protein CTD PMID:20025956 NCBI chr 8:39,181,162...39,201,588
Ensembl chr 8:39,181,163...39,243,882 		JBrowse link
G Crp C-reactive protein multiple interactions
increases expression		 EXP Carnosine inhibits the reaction [Sodium Nitrite results in increased expression of CRP protein] CTD PMID:28266762 PMID:28833918 NCBI chr13:91,080,448...91,081,358
Ensembl chr13:91,054,974...91,093,713 		JBrowse link
G G6pd glucose-6-phosphate dehydrogenase decreases activity ISO Sodium Nitrite results in decreased activity of G6PD protein CTD PMID:26231821 NCBI chr  X:156,274,800...156,293,935
Ensembl chr  X:156,274,800...156,293,926 		JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions
increases activity		 EXP Carnosine inhibits the reaction [Sodium Nitrite results in increased activity of GPT protein] CTD PMID:28833918 NCBI chr 7:117,759,083...117,761,932
Ensembl chr 7:117,759,083...117,761,931 		JBrowse link
G Gsr glutathione-disulfide reductase decreases activity ISO Sodium Nitrite results in decreased activity of GSR protein CTD PMID:26231821 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361 		JBrowse link
G Hells helicase, lymphoid specific increases expression ISO Sodium Nitrite results in increased expression of HELLS protein CTD PMID:20025956 NCBI chr 1:257,901,856...257,953,889
Ensembl chr 1:257,766,691...257,949,183
Ensembl chr 1:257,766,691...257,949,183 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha increases expression
multiple interactions		 EXP Sodium Nitrite results in increased expression of HIF1A protein
Carnosine inhibits the reaction [Sodium Nitrite results in increased expression of HIF1A protein]; Quercetin inhibits the reaction [Sodium Nitrite results in increased expression of HIF1A protein]		 CTD PMID:28000380 PMID:28266762 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052 		JBrowse link
G Il1b interleukin 1 beta increases expression
increases secretion		 ISO Sodium Nitrite results in increased expression of IL1B mRNA
Sodium Nitrite results in increased secretion of IL1B protein		 CTD PMID:16581224 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726 		JBrowse link
G Il1rl1 interleukin 1 receptor-like 1 increases expression ISO Sodium Nitrite results in increased expression of IL1RL1 protein CTD PMID:20025956 NCBI chr 9:47,133,483...47,184,316
Ensembl chr 9:47,134,034...47,182,170 		JBrowse link
G Il6 interleukin 6 increases secretion
increases expression
multiple interactions		 ISO
EXP		 Sodium Nitrite results in increased secretion of IL6 protein
Sodium Nitrite results in increased expression of IL6 protein
Carnosine inhibits the reaction [Sodium Nitrite results in increased expression of IL6 protein]		 CTD PMID:16581224 PMID:28266762 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807 		JBrowse link
G Ldhb lactate dehydrogenase B increases activity ISO Sodium Nitrite results in increased activity of LDHB protein CTD PMID:26231821 NCBI chr 4:176,701,980...176,719,999
Ensembl chr 4:176,701,983...176,720,012 		JBrowse link
G Mcm3 minichromosome maintenance complex component 3 increases expression ISO Sodium Nitrite results in increased expression of MCM3 protein CTD PMID:20025956 NCBI chr 9:26,914,057...26,932,201
Ensembl chr 9:26,914,057...26,932,201 		JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions
decreases expression		 EXP Carnosine inhibits the reaction [Sodium Nitrite results in decreased expression of NFKBIA mRNA] CTD PMID:28833918 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457 		JBrowse link
G Rad51ap1 RAD51 associated protein 1 increases expression ISO Sodium Nitrite results in increased expression of RAD51AP1 protein CTD PMID:20025956 NCBI chr 4:159,469,803...159,482,869
Ensembl chr 4:159,469,804...159,482,869 		JBrowse link
G Smad2 SMAD family member 2 increases expression
multiple interactions		 EXP Sodium Nitrite results in increased expression of SMAD2 protein
Carnosine inhibits the reaction [Sodium Nitrite results in increased expression of SMAD2 protein]; Quercetin inhibits the reaction [Sodium Nitrite results in increased expression of SMAD2 protein]		 CTD PMID:28000380 PMID:28266762 NCBI chr18:72,550,107...72,612,078
Ensembl chr18:72,550,219...72,612,078 		JBrowse link
G Stmn1 stathmin 1 increases expression ISO Sodium Nitrite results in increased expression of STMN1 protein CTD PMID:20025956 NCBI chr 5:152,680,412...152,686,807
Ensembl chr 5:152,680,407...152,686,806 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 increases expression
multiple interactions		 EXP Sodium Nitrite results in increased expression of TGFB1 protein
Carnosine inhibits the reaction [Sodium Nitrite results in increased expression of TGFB1 protein]		 CTD PMID:28266762 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199 		JBrowse link
G Tnf tumor necrosis factor increases expression
multiple interactions
increases secretion		 ISO
EXP		 Sodium Nitrite results in increased expression of TNF mRNA
Carnosine inhibits the reaction [Sodium Nitrite results in increased expression of TNF protein]
Sodium Nitrite results in increased secretion of TNF protein		 CTD PMID:16581224 PMID:28266762 PMID:28833918 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000 		JBrowse link
G Vegfa vascular endothelial growth factor A increases expression
multiple interactions		 EXP Sodium Nitrite results in increased expression of VEGFA protein
Carnosine inhibits the reaction [Sodium Nitrite results in increased expression of VEGFA protein]		 CTD PMID:28266762 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19883
    role 19833
      biological role 19833
        poison 18150
          sodium nitrite 29
Path 2
Term Annotations click to browse term
  CHEBI ontology 19883
    subatomic particle 19881
      composite particle 19881
        hadron 19881
          baryon 19881
            nucleon 19881
              atomic nucleus 19881
                atom 19881
                  main group element atom 19771
                    p-block element atom 19771
                      chalcogen 19464
                        oxygen atom 19425
                          oxygen molecular entity 19425
                            hydroxides 19147
                              oxoacid 18286
                                pnictogen oxoacid 10306
                                  nitrogen oxoacid 274
                                    nitrous acid 58
                                      nitrites 58
                                        nitrite salt 29
                                          sodium nitrite 29
paths to the root