|
G
|
Abcb11
|
ATP binding cassette subfamily B member 11
|
multiple interactions decreases activity
|
ISO
|
Reserpine inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid] Reserpine results in decreased activity of ABCB11 protein
|
CTD |
PMID:20829430 PMID:23956101 PMID:24014644 |
|
NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730
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G
|
Abcb1a
|
ATP binding cassette subfamily B member 1A
|
multiple interactions decreases activity increases expression
|
ISO
|
Cycloheximide promotes the reaction [Reserpine results in increased expression of ABCB1 mRNA]; Reserpine inhibits the reaction [ABCB1 protein affects the export of calcein AM]; Reserpine inhibits the reaction [ABCB1 protein results in increased secretion of fluorexon]; Reserpine inhibits the reaction [ABCB1 protein results in increased secretion of Vinblastine] Reserpine results in decreased activity of ABCB1 protein Reserpine results in increased expression of ABCB1 mRNA; Reserpine results in increased expression of ABCB1 protein Reserpine inhibits the reaction [ABCB1A protein results in increased secretion of fluorexon]
|
CTD |
PMID:7476894 PMID:8632764 PMID:10617675 PMID:12235267 PMID:19528478 |
|
NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:25,158,362...25,442,709
|
|
G
|
Abcg2
|
ATP binding cassette subfamily G member 2
|
multiple interactions
|
ISO
|
Reserpine inhibits the reaction [ABCG2 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]; Reserpine inhibits the reaction [ABCG2 protein results in increased transport of Irinotecan]
|
CTD |
PMID:12869632 |
|
NCBI chr 4:89,006,056...89,132,915
Ensembl chr 4:87,745,319...87,802,409
|
|
G
|
Ache
|
acetylcholinesterase
|
multiple interactions affects activity
|
EXP
|
[Plant Extracts results in increased abundance of Dronabinol] inhibits the reaction [Reserpine affects the activity of ACHE protein]
|
CTD |
PMID:28212939 |
|
NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651
|
|
G
|
Adra1d
|
adrenoceptor alpha 1D
|
increases response to substance increases expression
|
EXP
|
ADRA1D protein results in increased susceptibility to Reserpine Reserpine results in increased expression of ADRA1D mRNA
|
CTD |
PMID:15159276 PMID:17676312 |
|
NCBI chr 3:118,793,356...118,809,354
Ensembl chr 3:118,793,346...118,809,354
|
|
G
|
Adra2a
|
adrenoceptor alpha 2A
|
increases expression
|
EXP
|
Reserpine results in increased expression of ADRA2A mRNA
|
CTD |
PMID:11264240 |
|
NCBI chr 1:253,061,480...253,064,280
Ensembl chr 1:253,060,218...253,064,365
|
|
G
|
Adrb1
|
adrenoceptor beta 1
|
increases expression increases stability
|
EXP
|
Reserpine results in increased expression of ADRB1 mRNA; Reserpine results in increased expression of ADRB1 protein Reserpine results in increased stability of ADRB1 mRNA
|
CTD |
PMID:1336118 |
|
NCBI chr 1:255,771,962...255,774,973
Ensembl chr 1:255,771,597...255,807,259
|
|
G
|
Adrb2
|
adrenoceptor beta 2
|
increases expression
|
EXP
|
Reserpine results in increased expression of ADRB2 mRNA
|
CTD |
PMID:1664493 |
|
NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512
|
|
G
|
Agtr2
|
angiotensin II receptor, type 2
|
increases expression
|
EXP
|
Reserpine results in increased expression of AGTR2 mRNA; Reserpine results in increased expression of AGTR2 protein
|
CTD |
PMID:20964730 |
|
NCBI chr X:112,119,876...112,124,060
Ensembl chr X:112,120,228...112,124,057
|
|
G
|
Akr1b10
|
aldo-keto reductase family 1 member B10
|
increases expression
|
ISO
|
Reserpine results in increased expression of AKR1B10 mRNA
|
CTD |
PMID:26198647 |
|
NCBI chr 4:63,038,459...63,060,336
Ensembl chr 4:63,040,169...63,053,852
|
|
G
|
Akt1
|
AKT serine/threonine kinase 1
|
decreases phosphorylation multiple interactions
|
ISO
|
Reserpine results in decreased phosphorylation of AKT1 protein arsenic trioxide promotes the reaction [Reserpine results in decreased phosphorylation of AKT1 protein]
|
CTD |
PMID:26114099 |
|
NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:131,713,720...131,733,921
|
|
G
|
Amd1
|
adenosylmethionine decarboxylase 1
|
multiple interactions
|
ISO
|
Reserpine inhibits the reaction [Folic Acid results in increased activity of AMD1 protein]
|
CTD |
PMID:17371283 |
|
NCBI chr20:43,695,783...43,711,476
Ensembl chr20:43,697,237...43,711,476
|
|
G
|
Ar
|
androgen receptor
|
multiple interactions
|
ISO
|
Reserpine inhibits the reaction [Stanozolol binds to and results in increased activity of AR protein]
|
CTD |
PMID:29162470 |
|
NCBI chr X:67,135,317...67,304,476
Ensembl chr X:63,104,771...63,273,925
|
|
G
|
Arc
|
activity-regulated cytoskeleton-associated protein
|
multiple interactions
|
EXP
|
Reserpine inhibits the reaction [Cocaine results in increased expression of ARC mRNA]
|
CTD |
PMID:7722525 |
|
NCBI chr 7:106,555,968...106,559,697
Ensembl chr 7:106,555,785...106,559,378
|
|
G
|
Bax
|
BCL2 associated X, apoptosis regulator
|
multiple interactions increases expression
|
EXP
|
IAPP protein inhibits the reaction [Reserpine results in increased expression of BAX protein]
|
CTD |
PMID:19463876 |
|
NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:95,938,808...95,945,368
|
|
G
|
Bcl2
|
BCL2, apoptosis regulator
|
multiple interactions decreases expression
|
EXP
|
IAPP protein inhibits the reaction [Reserpine results in decreased expression of BCL2 protein]
|
CTD |
PMID:19463876 |
|
NCBI chr13:23,204,464...23,366,900
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
|
|
G
|
Bdnf
|
brain-derived neurotrophic factor
|
decreases expression multiple interactions
|
ISO EXP
|
Reserpine results in decreased expression of BDNF protein arsenic trioxide promotes the reaction [Reserpine results in decreased expression of BDNF protein] cerebrolysin inhibits the reaction [Reserpine results in decreased expression of BDNF protein]; Fluoxetine inhibits the reaction [Reserpine results in decreased expression of BDNF protein]
|
CTD |
PMID:26114099 PMID:33279466 |
|
NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
|
|
G
|
Birc5
|
baculoviral IAP repeat-containing 5
|
affects binding
|
ISO
|
Reserpine binds to BIRC5 promoter
|
CTD |
PMID:17968851 |
|
NCBI chr10:103,567,369...103,580,069
Ensembl chr10:103,073,408...103,081,380
|
|
G
|
C3
|
complement C3
|
affects expression
|
EXP
|
Reserpine affects the expression of C3 mRNA
|
CTD |
PMID:18363858 |
|
NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429
|
|
G
|
Casp3
|
caspase 3
|
multiple interactions increases activity
|
EXP
|
IAPP protein inhibits the reaction [Reserpine results in increased activity of CASP3 protein]
|
CTD |
PMID:19463876 |
|
NCBI chr16:52,395,539...52,413,794
Ensembl chr16:45,662,910...45,684,648
|
|
G
|
Casp8
|
caspase 8
|
multiple interactions increases activity
|
EXP
|
IAPP protein inhibits the reaction [Reserpine results in increased activity of CASP8 protein]
|
CTD |
PMID:19463876 |
|
NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:60,264,075...60,312,542
|
|
G
|
Cat
|
catalase
|
multiple interactions increases expression decreases expression
|
EXP
|
Plant Extracts inhibits the reaction [Reserpine results in decreased expression of CAT protein]; Quercetin inhibits the reaction [Reserpine results in decreased expression of CAT protein] Reserpine results in increased expression of CAT protein
|
CTD |
PMID:14685008 PMID:16444668 PMID:19109989 PMID:19761039 PMID:20628966 |
|
NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:89,842,399...89,874,478
|
|
G
|
Ccnd1
|
cyclin D1
|
decreases expression
|
ISO
|
Reserpine results in decreased expression of CCND1 mRNA; Reserpine results in decreased expression of CCND1 protein
|
CTD |
PMID:19607803 |
|
NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:200,089,002...200,098,602
|
|
G
|
Cdkn1b
|
cyclin-dependent kinase inhibitor 1B
|
multiple interactions
|
EXP
|
[troglitazone co-treated with [Hydrochlorothiazide co-treated with Hydralazine co-treated with Reserpine]] results in decreased expression of CDKN1B protein
|
CTD |
PMID:11318962 |
|
NCBI chr 4:169,491,273...169,496,500
Ensembl chr 4:167,760,181...167,764,982
|
|
G
|
Cdkn2a
|
cyclin-dependent kinase inhibitor 2A
|
multiple interactions
|
EXP
|
[Hydrochlorothiazide co-treated with Hydralazine co-treated with Reserpine] inhibits the reaction [Desoxycorticosterone Acetate affects the localization of CDKN2A protein]; [Hydrochlorothiazide co-treated with Hydralazine co-treated with Reserpine] inhibits the reaction [Desoxycorticosterone Acetate results in increased expression of CDKN2A mRNA]
|
CTD |
PMID:18504326 |
|
NCBI chr 5:109,100,763...109,114,448
Ensembl chr 5:103,984,949...104,003,149
|
|
G
|
Chga
|
chromogranin A
|
multiple interactions increases activity increases expression
|
ISO EXP
|
CHGA protein alternative form inhibits the reaction [Reserpine results in increased activity of CHGA promoter]; Chlorisondamine inhibits the reaction [Reserpine results in increased activity of CHGA promoter] Reserpine results in increased expression of CHGA mRNA
|
CTD |
PMID:1907749 PMID:8189248 PMID:12799369 |
|
NCBI chr 6:121,696,051...121,707,399
Ensembl chr 6:121,696,051...121,707,398
|
|
G
|
Chgb
|
chromogranin B
|
increases expression
|
EXP
|
Reserpine results in increased expression of CHGB mRNA; Reserpine results in increased expression of CHGB protein
|
CTD |
PMID:1907749 PMID:8189248 PMID:8361347 |
|
NCBI chr 3:120,043,824...120,057,169
Ensembl chr 3:120,043,738...120,057,166
|
|
G
|
Chrm1
|
cholinergic receptor, muscarinic 1
|
increases expression decreases expression
|
EXP
|
Reserpine results in increased expression of CHRM1 mRNA Reserpine results in decreased expression of CHRM1 protein
|
CTD |
PMID:1506860 |
|
NCBI chr 1:205,567,226...205,583,001
Ensembl chr 1:205,567,220...205,582,356
|
|
G
|
Cnr1
|
cannabinoid receptor 1
|
decreases expression
|
EXP
|
Reserpine results in decreased expression of CNR1 mRNA
|
CTD |
PMID:11358453 |
|
NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099
|
|
G
|
Cpe
|
carboxypeptidase E
|
increases expression
|
EXP
|
Reserpine results in increased expression of CPE mRNA
|
CTD |
PMID:8189248 |
|
NCBI chr16:25,030,276...25,142,231
Ensembl chr16:25,030,276...25,142,233
|
|
G
|
Crem
|
cAMP responsive element modulator
|
multiple interactions increases expression
|
EXP
|
Reserpine promotes the reaction [CREM protein binds to TH promoter] Reserpine results in increased expression of CREM mRNA alternative form; Reserpine results in increased expression of CREM protein; Reserpine results in increased expression of CREM protein alternative form
|
CTD |
PMID:8810303 PMID:11438978 |
|
NCBI chr17:54,238,889...54,305,989
Ensembl chr17:54,239,030...54,305,989
|
|
G
|
Crh
|
corticotropin releasing hormone
|
increases expression
|
EXP
|
Reserpine results in increased expression of CRH mRNA; Reserpine results in increased expression of CRH protein
|
CTD |
PMID:1850078 |
|
NCBI chr 2:102,143,055...102,144,919
Ensembl chr 2:102,143,055...102,144,919
|
|
G
|
Cyp1a1
|
cytochrome P450, family 1, subfamily a, polypeptide 1
|
multiple interactions
|
ISO
|
Reserpine inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]; Reserpine promotes the reaction [Benzo(a)pyrene results in increased expression of and results in increased activity of CYP1A1 protein]; Reserpine promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 mRNA]
|
CTD |
PMID:15627480 PMID:18493746 |
|
NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
|
|
G
|
Cyp1a2
|
cytochrome P450, family 1, subfamily a, polypeptide 2
|
multiple interactions
|
EXP
|
[Reserpine results in decreased abundance of Catecholamines] promotes the reaction [Benzo(a)pyrene results in increased expression of and results in increased activity of CYP1A2 protein]; [Reserpine results in decreased abundance of Catecholamines] promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA]; Reserpine promotes the reaction [Benzo(a)pyrene results in increased expression of and results in increased activity of CYP1A2 protein]; Reserpine promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA]
|
CTD |
PMID:16510159 |
|
NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
|
|
G
|
Cyp2b3
|
cytochrome P450, family 2, subfamily b, polypeptide 3
|
multiple interactions
|
ISO
|
[Reserpine results in increased activity of NR1I3 protein alternative form] which results in increased expression of CYP2B6 mRNA
|
CTD |
PMID:17041008 |
|
NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
|
|
G
|
Cyp3a2
|
cytochrome P450, family 3, subfamily a, polypeptide 2
|
increases expression multiple interactions
|
ISO
|
Reserpine results in increased expression of CYP3A4 mRNA; Reserpine results in increased expression of CYP3A4 protein [Reserpine results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA; Reserpine inhibits the reaction [Calcitriol results in increased expression of CYP3A4 protein]
|
CTD |
PMID:8632764 PMID:16837568 PMID:17041008 PMID:29782822 |
|
NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
|
|
G
|
Cyp3a9
|
cytochrome P450, family 3, subfamily a, polypeptide 9
|
increases expression
|
ISO
|
Reserpine results in increased expression of CYP3A5 protein
|
CTD |
PMID:8632764 |
|
NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422
|
|
G
|
Cyss
|
cystatin S
|
multiple interactions
|
EXP
|
Reserpine inhibits the reaction [Isoproterenol results in increased expression of CYSS mRNA]
|
CTD |
PMID:9447264 |
|
NCBI chr 3:137,432,049...137,436,654
Ensembl chr 3:137,432,049...137,436,610
|
|
G
|
Dbh
|
dopamine beta-hydroxylase
|
decreases activity increases activity increases stability increases expression
|
EXP
|
Reserpine results in decreased activity of DBH protein Reserpine results in increased activity of DBH protein Reserpine results in increased stability of DBH protein Reserpine results in increased expression of DBH mRNA
|
CTD |
PMID:1359376 PMID:2325165 PMID:7984052 PMID:8189248 |
|
NCBI chr 3:10,488,260...10,505,245
Ensembl chr 3:10,488,260...10,505,248
|
|
G
|
Ddc
|
dopa decarboxylase
|
increases expression
|
EXP
|
Reserpine results in increased expression of DDC mRNA
|
CTD |
PMID:1359376 |
|
NCBI chr14:86,378,685...86,469,189
Ensembl chr14:86,378,685...86,469,208
|
|
G
|
Drd1
|
dopamine receptor D1
|
increases expression
|
EXP
|
Reserpine results in increased expression of DRD1 mRNA
|
CTD |
PMID:8419537 |
|
NCBI chr17:10,540,440...10,544,971
Ensembl chr17:10,540,558...10,545,002
|
|
G
|
Drd2
|
dopamine receptor D2
|
multiple interactions increases expression
|
ISO EXP
|
DRD2 protein affects the susceptibility to [8-(3-chlorostyryl)caffeine co-treated with Reserpine] Reserpine results in increased expression of DRD2 mRNA; Reserpine results in increased expression of DRD2 mRNA alternative form
|
CTD |
PMID:1331675 PMID:8419537 PMID:11172060 |
|
NCBI chr 8:49,708,927...49,772,876
Ensembl chr 8:49,708,927...49,772,875
|
|
G
|
Egr1
|
early growth response 1
|
multiple interactions increases expression
|
EXP
|
[Reserpine co-treated with Levodopa] results in increased expression of EGR1 mRNA; eticlopride inhibits the reaction [[Reserpine co-treated with Levodopa] results in increased expression of EGR1 mRNA]; Quinpirole inhibits the reaction [Reserpine results in increased expression of EGR1 mRNA]; Reserpine promotes the reaction [Dextroamphetamine results in increased expression of EGR1 mRNA]; SCH 23390 inhibits the reaction [[Reserpine co-treated with Levodopa] results in increased expression of EGR1 mRNA]; SCH 23390 inhibits the reaction [Reserpine promotes the reaction [Dextroamphetamine results in increased expression of EGR1 mRNA]] Reserpine results in increased expression of EGR1 mRNA; Reserpine results in increased expression of EGR1 protein
|
CTD |
PMID:1347779 PMID:8063705 PMID:9729266 PMID:9890435 |
|
NCBI chr18:26,737,078...26,740,877
Ensembl chr18:26,462,981...26,466,766
|
|
G
|
Erbb2
|
erb-b2 receptor tyrosine kinase 2
|
increases response to substance
|
EXP
|
ERBB2 protein results in increased susceptibility to Reserpine
|
CTD |
PMID:8093862 |
|
NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078
|
|
G
|
Fabp7
|
fatty acid binding protein 7
|
affects expression
|
EXP
|
Reserpine affects the expression of FABP7 mRNA
|
CTD |
PMID:18363858 |
|
NCBI chr20:37,123,193...37,126,725
Ensembl chr20:37,123,193...37,126,880
|
|
G
|
Fos
|
Fos proto-oncogene, AP-1 transcription factor subunit
|
multiple interactions increases phosphorylation increases expression
|
EXP
|
2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine promotes the reaction [Reserpine results in increased expression of FOS protein]; 3,7-dimethyl-1-propargylxanthine inhibits the reaction [Reserpine results in increased expression of FOS protein]; 8-(3-chlorostyryl)caffeine promotes the reaction [Quinpirole inhibits the reaction [Reserpine results in increased expression of FOS protein]]; Quinpirole inhibits the reaction [Reserpine results in increased expression of FOS protein]; Quinpirole promotes the reaction [Reserpine results in increased expression of FOS protein]; Reserpine inhibits the reaction [[2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine co-treated with Quinpirole] results in increased expression of FOS protein]; Reserpine inhibits the reaction [Cocaine results in increased expression of FOS protein]; Reserpine promotes the reaction [2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine results in increased expression of FOS protein]; Reserpine promotes the reaction [Amphetamine results in increased expression of FOS protein]; Reserpine promotes the reaction [Quinpirole results in increased expression of FOS protein]; Theophylline inhibits the reaction [Reserpine results in increased expression of FOS protein] Reserpine results in increased phosphorylation of FOS protein Reserpine results in increased expression of FOS mRNA; Reserpine results in increased expression of FOS protein
|
CTD |
PMID:1359376 PMID:1686849 PMID:2118661 PMID:7845612 PMID:7914358 PMID:8100600 PMID:8102797 PMID:8577368 PMID:8864302 PMID:9210518 More...
|
|
NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
|
|
G
|
Gad1
|
glutamate decarboxylase 1
|
increases expression multiple interactions
|
EXP
|
Reserpine results in increased expression of GAD1 mRNA Clenbuterol inhibits the reaction [Reserpine results in increased expression of GAD1 mRNA]
|
CTD |
PMID:8774452 |
|
NCBI chr 3:55,369,704...55,410,335
Ensembl chr 3:55,369,704...55,410,333
|
|
G
|
Gal
|
galanin and GMAP prepropeptide
|
decreases expression multiple interactions increases expression
|
EXP
|
Reserpine results in decreased expression of GAL mRNA Desipramine inhibits the reaction [Reserpine results in increased expression of GAL mRNA]
|
CTD |
PMID:1279347 PMID:1698642 PMID:1705056 PMID:1717808 PMID:9512271 PMID:19598284 More...
|
|
NCBI chr 1:200,650,439...200,655,302
Ensembl chr 1:200,650,439...200,654,959
|
|
G
|
Gast
|
gastrin
|
multiple interactions
|
EXP
|
Reserpine inhibits the reaction [Levodopa results in decreased cleavage of GAST protein]
|
CTD |
PMID:10332097 |
|
NCBI chr10:85,264,832...85,269,393
Ensembl chr10:85,264,832...85,267,496
|
|
G
|
Gch1
|
GTP cyclohydrolase 1
|
increases expression
|
EXP
|
Reserpine results in increased expression of GCH1 mRNA; Reserpine results in increased expression of GCH1 mRNA alternative form
|
CTD |
PMID:8103077 |
|
NCBI chr15:20,404,267...20,437,727
Ensembl chr15:20,402,527...20,437,698
|
|
G
|
Gcnt3
|
glucosaminyl (N-acetyl) transferase 3, mucin type
|
increases expression
|
ISO
|
Reserpine results in increased expression of GCNT3 mRNA
|
CTD |
PMID:26198647 |
|
NCBI chr 8:70,689,173...70,696,476
Ensembl chr 8:70,686,844...70,699,562
|
|
G
|
Gnai1
|
G protein subunit alpha i1
|
increases expression
|
EXP
|
Reserpine results in increased expression of GNAI1 protein
|
CTD |
PMID:11264240 |
|
NCBI chr 4:16,814,000...16,898,119
Ensembl chr 4:16,814,001...16,896,417
|
|
G
|
Gnai2
|
G protein subunit alpha i2
|
increases expression
|
EXP
|
Reserpine results in increased expression of GNAI2 mRNA; Reserpine results in increased expression of GNAI2 protein
|
CTD |
PMID:8419537 PMID:11264240 |
|
NCBI chr 8:108,288,401...108,309,009
Ensembl chr 8:108,288,401...108,308,979
|
|
G
|
Gnai3
|
G protein subunit alpha i3
|
increases expression
|
EXP
|
Reserpine results in increased expression of GNAI3 protein
|
CTD |
PMID:11264240 |
|
NCBI chr 2:195,742,765...195,780,720
Ensembl chr 2:195,742,642...195,780,742
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|
G
|
Gnao1
|
G protein subunit alpha o1
|
increases expression
|
EXP
|
Reserpine results in increased expression of GNAO1 mRNA; Reserpine results in increased expression of GNAO1 protein
|
CTD |
PMID:8419537 PMID:11264240 |
|
NCBI chr19:11,034,874...11,192,531
Ensembl chr19:11,035,956...11,192,493
|
|
G
|
Gnas
|
GNAS complex locus
|
increases expression decreases expression
|
EXP
|
Reserpine results in increased expression of GNAS mRNA; Reserpine results in increased expression of GNAS protein Reserpine results in decreased expression of GNAS protein alternative form
|
CTD |
PMID:1336118 PMID:8419537 PMID:11264240 |
|
NCBI chr 3:163,071,003...163,136,350
Ensembl chr 3:163,071,417...163,127,262 Ensembl chr 3:163,071,417...163,127,262
|
|
G
|
Grm5
|
glutamate metabotropic receptor 5
|
decreases expression increases expression
|
EXP
|
Reserpine results in decreased expression of GRM5 mRNA Reserpine results in increased expression of GRM5 protein
|
CTD |
PMID:16890937 |
|
NCBI chr 1:141,310,069...141,884,980
Ensembl chr 1:141,312,368...141,882,274
|
|
G
|
Hgf
|
hepatocyte growth factor
|
increases expression
|
EXP
|
Reserpine results in increased expression of HGF protein
|
CTD |
PMID:16081063 |
|
NCBI chr 4:18,673,736...18,745,582
Ensembl chr 4:18,677,101...18,745,409
|
|
G
|
Hspg2
|
heparan sulfate proteoglycan 2
|
multiple interactions
|
ISO
|
HSPG2 gene results in increased susceptibility to [Haloperidol co-treated with Reserpine]
|
CTD |
PMID:20072119 |
|
NCBI chr 5:149,677,437...149,778,594
Ensembl chr 5:149,677,476...149,778,594
|
|
G
|
Htr1a
|
5-hydroxytryptamine receptor 1A
|
decreases expression
|
ISO
|
Reserpine results in decreased expression of HTR1A protein
|
CTD |
PMID:26114099 |
|
NCBI chr 2:36,693,462...36,698,026
Ensembl chr 2:36,694,174...36,695,442
|
|
G
|
Iapp
|
islet amyloid polypeptide
|
multiple interactions
|
EXP
|
IAPP protein inhibits the reaction [Reserpine results in decreased expression of BCL2 protein]; IAPP protein inhibits the reaction [Reserpine results in increased activity of CASP3 protein]; IAPP protein inhibits the reaction [Reserpine results in increased activity of CASP8 protein]; IAPP protein inhibits the reaction [Reserpine results in increased expression of BAX protein]; IAPP protein inhibits the reaction [Reserpine results in increased expression of TNFSF10 protein]
|
CTD |
PMID:19463876 |
|
NCBI chr 4:175,237,107...175,244,373
Ensembl chr 4:175,237,115...175,242,920
|
|
G
|
Il10
|
interleukin 10
|
decreases expression multiple interactions
|
ISO
|
Reserpine results in decreased expression of IL10 mRNA; Reserpine results in decreased expression of IL10 protein SCH 23390 inhibits the reaction [Reserpine results in decreased expression of IL10 mRNA]; SCH 23390 inhibits the reaction [Reserpine results in decreased expression of IL10 protein]
|
CTD |
PMID:16985181 |
|
NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
|
|
G
|
Il18
|
interleukin 18
|
increases expression
|
EXP
|
Reserpine results in increased expression of IL18 mRNA
|
CTD |
PMID:8999896 |
|
NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
|
|
G
|
Jun
|
Jun proto-oncogene, AP-1 transcription factor subunit
|
increases expression
|
EXP
|
Reserpine results in increased expression of JUN mRNA
|
CTD |
PMID:1359376 |
|
NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:109,893,145...109,897,656
|
|
G
|
Junb
|
JunB proto-oncogene, AP-1 transcription factor subunit
|
multiple interactions
|
EXP
|
Reserpine promotes the reaction [Dextroamphetamine results in increased expression of JUNB mRNA]; SCH 23390 inhibits the reaction [Reserpine promotes the reaction [Dextroamphetamine results in increased expression of JUNB mRNA]]
|
CTD |
PMID:1347779 |
|
NCBI chr19:40,081,126...40,082,910
Ensembl chr19:23,176,294...23,178,035
|
|
G
|
Kcna3
|
potassium voltage-gated channel subfamily A member 3
|
decreases activity multiple interactions
|
ISO
|
Reserpine results in decreased activity of KCNA3 protein [Reserpine results in decreased activity of KCNA3 protein] which results in decreased import of Thallium
|
CTD |
PMID:21362439 |
|
NCBI chr 2:194,632,106...194,634,059
Ensembl chr 2:194,632,196...194,650,138
|
|
G
|
Kcna5
|
potassium voltage-gated channel subfamily A member 5
|
increases expression
|
EXP
|
Reserpine results in increased expression of KCNA5 mRNA
|
CTD |
PMID:12606256 |
|
NCBI chr 4:159,354,689...159,358,173
Ensembl chr 4:159,350,097...159,357,697
|
|
G
|
Kcnd2
|
potassium voltage-gated channel subfamily D member 2
|
decreases expression
|
EXP
|
Reserpine results in decreased expression of KCND2 mRNA
|
CTD |
PMID:12606256 |
|
NCBI chr 4:49,775,812...50,277,746
Ensembl chr 4:49,776,246...50,277,728
|
|
G
|
Kcnd3
|
potassium voltage-gated channel subfamily D member 3
|
decreases expression
|
EXP
|
Reserpine results in decreased expression of KCND3 mRNA
|
CTD |
PMID:12606256 |
|
NCBI chr 2:192,937,950...193,155,345
Ensembl chr 2:192,937,950...193,155,345
|
|
G
|
Kcnh2
|
potassium voltage-gated channel subfamily H member 2
|
decreases activity multiple interactions
|
ISO
|
Reserpine results in decreased activity of KCNH2 protein [Reserpine results in decreased activity of KCNH2 protein] which results in decreased import of Thallium
|
CTD |
PMID:21362439 PMID:28551711 |
|
NCBI chr 4:11,719,357...11,751,424
Ensembl chr 4:10,826,928...10,859,008
|
|
G
|
Lep
|
leptin
|
increases expression
|
ISO
|
Reserpine results in increased expression of LEP mRNA
|
CTD |
PMID:10050748 |
|
NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
|
|
G
|
Myc
|
MYC proto-oncogene, bHLH transcription factor
|
increases response to substance decreases expression
|
ISO
|
MYC protein results in increased susceptibility to Reserpine Reserpine results in decreased expression of MYC protein
|
CTD |
PMID:8093862 PMID:19607803 |
|
NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:93,593,705...93,598,630
|
|
G
|
Ncf1
|
neutrophil cytosolic factor 1
|
increases expression
|
EXP
|
Reserpine results in increased expression of NCF1 mRNA; Reserpine results in increased expression of NCF1 protein
|
CTD |
PMID:20964730 |
|
NCBI chr12:22,485,382...22,494,647
Ensembl chr12:22,485,451...22,494,646
|
|
G
|
Nfe2l2
|
NFE2 like bZIP transcription factor 2
|
decreases activity
|
ISO
|
Reserpine results in decreased activity of NFE2L2 protein
|
CTD |
PMID:30203046 |
|
NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
|
|
G
|
Ngf
|
nerve growth factor
|
increases expression
|
EXP
|
Reserpine results in increased expression of NGF mRNA; Reserpine results in increased expression of NGF protein
|
CTD |
PMID:1996081 PMID:8593794 |
|
NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452
|
|
G
|
Nos1
|
nitric oxide synthase 1
|
increases expression
|
EXP
|
Reserpine results in increased expression of NOS1 mRNA; Reserpine results in increased expression of NOS1 protein
|
CTD |
PMID:7533141 |
|
NCBI chr12:38,615,111...38,795,492
Ensembl chr12:38,626,714...38,710,945
|
|
G
|
Npy
|
neuropeptide Y
|
multiple interactions decreases expression increases expression
|
EXP
|
Chlorisondamine inhibits the reaction [Reserpine results in increased expression of NPY mRNA]; Chlorisondamine promotes the reaction [Reserpine results in increased expression of NPY mRNA]; Dexamethasone inhibits the reaction [Reserpine results in increased expression of NPY mRNA] Reserpine results in decreased expression of NPY mRNA; Reserpine results in decreased expression of NPY protein Reserpine results in increased expression of NPY mRNA; Reserpine results in increased expression of NPY protein
|
CTD |
PMID:1671012 PMID:1676830 PMID:1687976 PMID:1698642 PMID:1713314 PMID:1714554 PMID:1878751 PMID:1907749 PMID:2233698 PMID:2897091 PMID:2903502 PMID:3215285 PMID:3805164 PMID:7644023 PMID:7911764 PMID:8189248 PMID:20504635 More...
|
|
NCBI chr 4:78,881,294...78,888,495
Ensembl chr 4:78,881,264...78,888,495
|
|
G
|
Nr1i2
|
nuclear receptor subfamily 1, group I, member 2
|
multiple interactions
|
ISO
|
[Reserpine results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA
|
CTD |
PMID:17041008 |
|
NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
|
|
G
|
Nr1i3
|
nuclear receptor subfamily 1, group I, member 3
|
multiple interactions decreases activity
|
ISO
|
[Reserpine results in increased activity of NR1I3 protein alternative form] which results in increased expression of CYP2B6 mRNA Reserpine results in decreased activity of NR1I3 protein
|
CTD |
PMID:17041008 PMID:30203046 |
|
NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906
|
|
G
|
Nr3c1
|
nuclear receptor subfamily 3, group C, member 1
|
increases expression
|
EXP
|
Reserpine results in increased expression of NR3C1 mRNA
|
CTD |
PMID:7984052 |
|
NCBI chr18:31,522,783...31,644,508
Ensembl chr18:31,271,681...31,393,375
|
|
G
|
Ntrk2
|
neurotrophic receptor tyrosine kinase 2
|
multiple interactions decreases expression
|
ISO
|
arsenic trioxide promotes the reaction [Reserpine results in decreased expression of NTRK2 protein]
|
CTD |
PMID:26114099 |
|
NCBI chr17:5,558,992...5,870,299
Ensembl chr17:5,559,043...5,869,136
|
|
G
|
Nts
|
neurotensin
|
increases expression
|
EXP
|
Reserpine results in increased expression of NTS mRNA
|
CTD |
PMID:1850078 |
|
NCBI chr 7:37,564,944...37,574,350
Ensembl chr 7:37,564,533...37,574,423
|
|
G
|
Odc1
|
ornithine decarboxylase 1
|
decreases expression multiple interactions
|
EXP ISO
|
Reserpine results in decreased expression of ODC1 protein Reserpine inhibits the reaction [CB 3717 results in increased activity of ODC1 protein]; Reserpine inhibits the reaction [CB 3717 results in increased expression of ODC1 mRNA]; Reserpine inhibits the reaction [Testosterone results in increased activity of ODC1 protein]; Reserpine inhibits the reaction [Testosterone results in increased expression of ODC1 mRNA]
|
CTD |
PMID:6519379 PMID:9194572 PMID:10354516 PMID:17371283 |
|
NCBI chr 6:40,329,831...40,336,444
Ensembl chr 6:40,329,964...40,336,440
|
|
G
|
Pam
|
peptidylglycine alpha-amidating monooxygenase
|
increases expression
|
EXP
|
Reserpine results in increased expression of PAM mRNA
|
CTD |
PMID:8189248 |
|
NCBI chr 9:97,998,581...98,271,966
Ensembl chr 9:98,122,916...98,271,965
|
|
G
|
Pcna
|
proliferating cell nuclear antigen
|
multiple interactions
|
EXP
|
[troglitazone co-treated with [Hydrochlorothiazide co-treated with Hydralazine co-treated with Reserpine]] results in decreased expression of PCNA protein
|
CTD |
PMID:11318962 |
|
NCBI chr 3:139,951,948...139,955,820
Ensembl chr 3:119,498,810...119,502,995
|
|
G
|
Pcsk2
|
proprotein convertase subtilisin/kexin type 2
|
increases expression
|
EXP
|
Reserpine results in increased expression of PCSK2 mRNA
|
CTD |
PMID:8189248 |
|
NCBI chr 3:130,880,422...131,183,127
Ensembl chr 3:130,880,422...131,183,127
|
|
G
|
Penk
|
proenkephalin
|
multiple interactions decreases expression increases expression
|
EXP
|
Apomorphine inhibits the reaction [Reserpine results in increased expression of PENK mRNA] Reserpine results in decreased expression of PENK mRNA Reserpine results in increased expression of PENK mRNA; Reserpine results in increased expression of PENK protein
|
CTD |
PMID:1331675 PMID:1850078 PMID:3188958 PMID:3838946 PMID:4078631 PMID:7494455 PMID:17719177 More...
|
|
NCBI chr 5:17,183,799...17,189,160
Ensembl chr 5:17,183,806...17,189,129
|
|
G
|
Pnmt
|
phenylethanolamine-N-methyltransferase
|
multiple interactions decreases expression increases expression
|
EXP
|
Chlorisondamine inhibits the reaction [Reserpine results in decreased expression of PNMT mRNA]; Dexamethasone inhibits the reaction [Reserpine results in decreased expression of PNMT mRNA]; POMC protein alternative form inhibits the reaction [Reserpine results in decreased expression of PNMT mRNA]; Reserpine results in increased expression of and results in increased activity of PNMT protein Reserpine results in increased expression of PNMT mRNA
|
CTD |
PMID:1359376 PMID:1687976 PMID:1714554 PMID:2903502 PMID:8063705 PMID:8479280 PMID:20504635 More...
|
|
NCBI chr10:83,383,019...83,386,557
Ensembl chr10:83,384,923...83,386,556
|
|
G
|
Pomc
|
proopiomelanocortin
|
increases expression multiple interactions
|
EXP
|
Reserpine results in increased expression of POMC mRNA; Reserpine results in increased expression of POMC protein alternative form POMC protein alternative form inhibits the reaction [Reserpine results in decreased expression of PNMT mRNA]
|
CTD |
PMID:8479280 PMID:20504635 |
|
NCBI chr 6:26,939,844...26,945,666
Ensembl chr 6:26,939,837...26,945,664
|
|
G
|
Prkaca
|
protein kinase cAMP-activated catalytic subunit alpha
|
decreases expression
|
ISO
|
Reserpine results in decreased expression of PRKACA protein
|
CTD |
PMID:26114099 |
|
NCBI chr19:24,155,081...24,178,430
Ensembl chr19:24,155,090...24,178,430
|
|
G
|
Prl
|
prolactin
|
increases expression
|
EXP
|
Reserpine results in increased expression of PRL protein
|
CTD |
PMID:11071396 |
|
NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062
|
|
G
|
Prss1
|
serine protease 1
|
decreases expression increases expression
|
EXP
|
Reserpine results in decreased expression of PRSS1 protein Reserpine results in increased expression of PRSS1 protein
|
CTD |
PMID:8625754 |
|
NCBI chr 4:70,364,589...70,367,792
Ensembl chr 4:70,364,586...70,367,792
|
|
G
|
Ptgs2
|
prostaglandin-endoperoxide synthase 2
|
increases expression
|
EXP
|
Reserpine results in increased expression of PTGS2 protein
|
CTD |
PMID:16081063 |
|
NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
|
|
G
|
Pts
|
6-pyruvoyl-tetrahydropterin synthase
|
increases expression
|
EXP
|
Reserpine results in increased expression of PTS mRNA
|
CTD |
PMID:7545485 |
|
NCBI chr 8:50,870,838...50,877,869
Ensembl chr 8:50,870,841...50,877,869
|
|
G
|
Rasd2
|
RASD family, member 2
|
decreases expression
|
EXP
|
Reserpine results in decreased expression of RASD2 mRNA
|
CTD |
PMID:16352400 |
|
NCBI chr19:13,594,291...13,605,016
Ensembl chr19:13,594,291...13,605,016
|
|
G
|
Rgs10
|
regulator of G-protein signaling 10
|
decreases expression
|
EXP
|
Reserpine results in decreased expression of RGS10 mRNA
|
CTD |
PMID:14505795 |
|
NCBI chr 1:192,376,772...192,422,640
Ensembl chr 1:182,946,336...182,987,697
|
|
G
|
Rgs2
|
regulator of G-protein signaling 2
|
decreases expression
|
EXP
|
Reserpine results in decreased expression of RGS2 mRNA
|
CTD |
PMID:14505795 |
|
NCBI chr13:55,799,749...55,802,354
Ensembl chr13:55,798,829...55,802,385
|
|
G
|
Rgs4
|
regulator of G-protein signaling 4
|
decreases expression
|
EXP
|
Reserpine results in decreased expression of RGS4 mRNA
|
CTD |
PMID:14505795 |
|
NCBI chr13:81,936,775...81,943,103
Ensembl chr13:81,936,775...81,943,068
|
|
G
|
Rgs5
|
regulator of G-protein signaling 5
|
decreases expression
|
EXP
|
Reserpine results in decreased expression of RGS5 mRNA
|
CTD |
PMID:14505795 |
|
NCBI chr13:81,848,254...81,885,053
Ensembl chr13:81,836,304...81,885,518
|
|
G
|
Rgs8
|
regulator of G-protein signaling 8
|
decreases expression
|
EXP
|
Reserpine results in decreased expression of RGS8 mRNA
|
CTD |
PMID:14505795 |
|
NCBI chr13:65,804,703...65,848,955
Ensembl chr13:65,804,797...65,846,807
|
|
G
|
Rgs9
|
regulator of G-protein signaling 9
|
affects response to substance decreases expression
|
ISO EXP
|
RGS9 affects the susceptibility to Reserpine Reserpine results in decreased expression of RGS9 mRNA
|
CTD |
PMID:14505795 PMID:15728856 |
|
NCBI chr10:94,195,265...94,270,892
Ensembl chr10:94,197,054...94,270,892
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|
G
|
Scg2
|
secretogranin II
|
increases expression
|
EXP
|
Reserpine results in increased expression of SCG2 mRNA
|
CTD |
PMID:1907749 PMID:8189248 PMID:8361347 |
|
NCBI chr 9:80,803,074...80,808,646
Ensembl chr 9:80,803,075...80,821,097
|
|
G
|
Serpine1
|
serpin family E member 1
|
multiple interactions
|
EXP
|
[troglitazone co-treated with [Hydrochlorothiazide co-treated with Hydralazine co-treated with Reserpine]] results in decreased expression of SERPINE1 mRNA; [troglitazone co-treated with [Hydrochlorothiazide co-treated with Hydralazine co-treated with Reserpine]] results in decreased expression of SERPINE1 protein
|
CTD |
PMID:11318962 |
|
NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
|
|
G
|
Siah1
|
siah E3 ubiquitin protein ligase 1
|
increases expression
|
ISO
|
Reserpine results in increased expression of SIAH1 mRNA
|
CTD |
PMID:19607803 |
|
NCBI chr19:36,552,165...36,575,773
Ensembl chr19:20,378,439...20,403,808
|
|
G
|
Slc18a1
|
solute carrier family 18 member A1
|
decreases activity multiple interactions
|
ISO
|
Reserpine results in decreased activity of SLC18A1 protein Reserpine inhibits the reaction [SLC18A1 protein results in increased uptake of Serotonin]
|
CTD |
PMID:8245983 PMID:21712771 |
|
NCBI chr16:20,653,268...20,687,051
Ensembl chr16:20,653,508...20,687,051
|
|
G
|
Slc18a2
|
solute carrier family 18 member A2
|
affects binding decreases response to substance decreases activity multiple interactions affects response to substance increases expression
|
ISO EXP
|
Reserpine binds to SLC18A2 protein SLC18A2 gene SNP results in decreased susceptibility to Reserpine Reserpine results in decreased activity of SLC18A2 protein Reserpine inhibits the reaction [SLC18A2 protein results in increased uptake of Serotonin]; Serotonin inhibits the reaction [SLC18A2 protein binds to Reserpine] SLC18A2 affects the susceptibility to Reserpine Reserpine results in increased expression of SLC18A2 mRNA Reserpine inhibits the reaction [SLC18A2 protein results in increased uptake of Dopamine]
|
CTD |
PMID:1438304 PMID:7912402 PMID:8189248 PMID:9038139 PMID:15475732 PMID:17664021 PMID:18287335 PMID:29908239 PMID:33378168 More...
|
|
NCBI chr 1:258,413,748...258,449,143
Ensembl chr 1:258,413,959...258,448,325
|
|
G
|
Slc6a2
|
solute carrier family 6 member 2
|
decreases expression
|
EXP
|
Reserpine results in decreased expression of SLC6A2 mRNA
|
CTD |
PMID:7478180 PMID:7616203 |
|
NCBI chr19:14,010,292...14,055,317
Ensembl chr19:14,010,386...14,050,357
|
|
G
|
Slc6a3
|
solute carrier family 6 member 3
|
decreases activity affects response to substance
|
ISO
|
Reserpine results in decreased activity of SLC6A3 protein SLC6A3 gene mutant form affects the susceptibility to Reserpine
|
CTD |
PMID:17664021 PMID:19615345 |
|
NCBI chr 1:29,709,443...29,750,413
Ensembl chr 1:29,709,443...29,750,413
|
|
G
|
Slc6a4
|
solute carrier family 6 member 4
|
decreases expression
|
EXP
|
Reserpine results in decreased expression of SLC6A4 mRNA
|
CTD |
PMID:10027743 |
|
NCBI chr10:61,824,208...61,858,924
Ensembl chr10:61,826,123...61,858,384
|
|
G
|
Snca
|
synuclein alpha
|
affects response to substance multiple interactions increases expression
|
ISO EXP
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SNCA protein mutant form affects the susceptibility to Reserpine [Levodopa co-treated with Carbidopa] inhibits the reaction [Reserpine results in increased expression of SNCA protein]; Dextromethorphan promotes the reaction [zolmitriptan inhibits the reaction [Reserpine results in increased expression of SNCA protein]]; Glutamic Acid inhibits the reaction [zolmitriptan inhibits the reaction [Reserpine results in increased expression of SNCA protein]]; zolmitriptan inhibits the reaction [Reserpine results in increased expression of SNCA protein]
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CTD |
PMID:18622040 PMID:38229316 |
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NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262
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G
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Sqstm1
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sequestosome 1
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increases expression
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ISO
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Reserpine results in increased expression of SQSTM1 mRNA
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CTD |
PMID:26198647 |
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NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673
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G
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Syt7
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synaptotagmin 7
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multiple interactions
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EXP
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[Reserpine co-treated with Apomorphine] results in increased expression of SYT7 mRNA
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CTD |
PMID:17719177 |
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NCBI chr 1:207,031,359...207,093,787
Ensembl chr 1:207,031,592...207,089,026
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G
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Tac1
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tachykinin, precursor 1
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multiple interactions increases expression
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EXP
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[2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine co-treated with Reserpine co-treated with Quinpirole] results in increased expression of TAC1 mRNA; [2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine co-treated with Reserpine] results in increased expression of TAC1 mRNA; Apomorphine promotes the reaction [Reserpine results in increased expression of TAC1 mRNA]
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CTD |
PMID:9751140 PMID:17719177 |
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NCBI chr 4:35,679,183...35,687,180
Ensembl chr 4:35,679,704...35,687,178
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G
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Tff1
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trefoil factor 1
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increases expression
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ISO
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Reserpine results in increased expression of TFF1 mRNA
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CTD |
PMID:35307500 |
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NCBI chr20:9,237,095...9,240,956
Ensembl chr20:9,235,736...9,239,597
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G
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Th
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tyrosine hydroxylase
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increases expression multiple interactions increases stability affects activity decreases expression increases activity
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ISO EXP
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Reserpine results in increased expression of TH mRNA Bicuculline promotes the reaction [Reserpine affects the activity of TH protein]; Bicuculline promotes the reaction [Reserpine results in increased expression of TH mRNA]; Chlorisondamine inhibits the reaction [Reserpine results in increased expression of TH mRNA]; Chlorisondamine promotes the reaction [Reserpine results in increased expression of TH mRNA]; Desipramine inhibits the reaction [Reserpine results in increased expression of TH mRNA]; Reserpine promotes the reaction [CREM protein binds to TH promoter]; Reserpine results in increased expression of and results in increased activity of TH protein Reserpine results in increased stability of TH mRNA Reserpine results in decreased expression of TH mRNA Reserpine results in increased expression of TH mRNA; Reserpine results in increased expression of TH protein Reserpine results in increased activity of TH protein
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CTD |
PMID:1350653 PMID:1359376 PMID:1676830 PMID:1687822 PMID:1687976 PMID:1698642 PMID:1705056 PMID:1714554 PMID:1717808 PMID:1970845 PMID:1976760 PMID:1978789 PMID:1981253 PMID:2568627 PMID:2862954 PMID:2863328 PMID:2872048 PMID:2881815 PMID:2882513 PMID:2883324 PMID:2903502 PMID:7478180 PMID:7532593 PMID:7545485 PMID:7616203 PMID:7911764 PMID:8369965 PMID:8666980 PMID:9210518 PMID:9691425 PMID:11161478 PMID:11438978 PMID:20504635 More...
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NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767
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G
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Tnf
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tumor necrosis factor
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increases expression multiple interactions
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EXP
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Reserpine results in increased expression of TNF protein cerebrolysin inhibits the reaction [Reserpine results in increased expression of TNF protein]; Fluoxetine inhibits the reaction [Reserpine results in increased expression of TNF protein]
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CTD |
PMID:33279466 |
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NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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G
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Tnfsf10
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TNF superfamily member 10
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multiple interactions increases expression
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EXP
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IAPP protein inhibits the reaction [Reserpine results in increased expression of TNFSF10 protein]
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CTD |
PMID:19463876 |
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NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135
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G
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Tph1
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tryptophan hydroxylase 1
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increases activity decreases activity
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EXP
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Reserpine results in increased activity of TPH1 protein Reserpine results in decreased activity of TPH1 protein
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CTD |
PMID:8369965 |
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NCBI chr 1:97,157,375...97,178,415
Ensembl chr 1:97,157,409...97,178,344
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G
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Vgf
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VGF nerve growth factor inducible
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increases expression
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EXP
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Reserpine results in increased expression of VGF mRNA
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CTD |
PMID:8189248 |
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NCBI chr12:19,637,313...19,645,123
Ensembl chr12:19,637,320...19,640,341
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G
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Vip
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vasoactive intestinal peptide
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increases expression
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EXP
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Reserpine results in increased expression of VIP mRNA
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CTD |
PMID:1850078 |
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NCBI chr 1:42,064,878...42,073,219
Ensembl chr 1:42,065,120...42,073,216
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