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ONTOLOGY REPORT - ANNOTATIONS


Term:flucytosine
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Accession:CHEBI:5100 term browser browse the term
Definition:An organofluorine compound that is cytosine that is substituted at position 5 by a fluorine. A prodrug for the antifungal 5-fluorouracil, it is used for the treatment of systemic fungal infections.
Synonyms:exact_synonym: 4-amino-5-fluoropyrimidin-2(1H)-one
 related_synonym: 5-FC;   5-Fluorocystosine;   5-Fluorocytosine;   Ancobon (TN);   Ancotil;   Formula=C4H4FN3O;   InChI=1S/C4H4FN3O/c5-2-1-7-4(9)8-3(2)6/h1H,(H3,6,7,8,9);   InChIKey=XRECTZIEBJDKEO-UHFFFAOYSA-N;   SMILES=Nc1nc(=O)[nH]cc1F;   flucytosina;   flucytosinum
 xref: CAS:2022-85-7 "ChemIDplus";   CAS:2022-85-7 "KEGG DRUG";   DrugBank:DB01099;   Drug_Central:1188 "DrugCentral";   HMDB:HMDB0015231;   KEGG:D00323;   LINCS:LSM-5878
 xref_mesh: MESH:D005437
 xref: PDBeChem:1LD;   PMID:11519290 "Europe PMC";   PMID:14871609 "Europe PMC";   PMID:18731030 "Europe PMC";   PMID:23576540 "Europe PMC";   PMID:25649231 "Europe PMC";   PMID:26201447 "Europe PMC";   PMID:28166217 "Europe PMC";   Patent:US2802005;   Patent:US2945038;   Patent:US3040026;   Wikipedia:Flucytosine


show annotations for term's descendants       view all columns           Sort by:
 
flucytosine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bcl2 BCL2, apoptosis regulator JBrowse link 13 26,605,426 26,769,374 RGD:6480464
G Mdm2 MDM2 proto-oncogene JBrowse link 7 60,719,060 60,743,618 RGD:6480464
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19614
    role 19557
      application 19155
        pro-agent 8775
          prodrug 8572
            flucytosine 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 19614
    subatomic particle 19610
      composite particle 19610
        hadron 19610
          baryon 19610
            nucleon 19610
              atomic nucleus 19610
                atom 19610
                  main group element atom 19489
                    main group molecular entity 19489
                      s-block molecular entity 19262
                        hydrogen molecular entity 19253
                          hydrides 18169
                            inorganic hydride 17110
                              pnictogen hydride 17068
                                nitrogen hydride 16891
                                  azane 16565
                                    ammonia 16562
                                      organic amino compound 16561
                                        aromatic amine 13561
                                          aminopyrimidine 1027
                                            cytosine 926
                                              flucytosine 3
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