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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:aminopyrimidine
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Accession:CHEBI:38338 term browser browse the term
Definition:A member of the class of pyrimidines that is pyrimidine substituted by at least one amino group and its derivatives.
Synonyms:related_synonym: aminopyrimidines


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2'-deoxycytidine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 multiple interactions ISO Deoxycytidine inhibits the reaction [[9-deaza-9-(3-thienylmethyl)guanine co-treated with Deoxyguanosine] results in increased activity of CASP3 protein] CTD PMID:9297556, PMID:9403342 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Dck deoxycytidine kinase affects binding ISO Deoxycytidine binds to DCK protein CTD PMID:17530837 NCBI chr14:20,935,442...20,952,939
Ensembl chr14:20,935,369...20,953,095
JBrowse link
G Slc28a1 solute carrier family 28 member 1 increases transport ISO SLC28A1 protein results in increased transport of Deoxycytidine CTD PMID:10772724 NCBI chr 1:142,948,942...142,992,410
Ensembl chr 1:142,950,540...142,992,615
JBrowse link
2,6-diamino-5-formamido-4-hydroxypyrimidine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Neil1 nei-like DNA glycosylase 1 affects metabolic processing ISO NEIL1 protein affects the metabolism of 2,6-diamino-4-hydroxy-5-formamidopyrimidine CTD PMID:17389588, PMID:20067321 NCBI chr 8:61,817,258...61,824,023
Ensembl chr 8:61,817,258...61,823,102
JBrowse link
G Ogg1 8-oxoguanine DNA glycosylase affects metabolic processing ISO OGG1 protein affects the metabolism of 2,6-diamino-4-hydroxy-5-formamidopyrimidine CTD PMID:20067321 NCBI chr 4:145,282,828...145,289,367
Ensembl chr 4:145,282,797...145,289,326
JBrowse link
3'-CMP term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdipt CDP-diacylglycerol--inositol 3-phosphatidyltransferase multiple interactions ISO [delta-hexachlorocyclohexane results in decreased activity of CDIPT protein] which results in decreased abundance of Cytidine Monophosphate; [Inositol promotes the reaction [CDIPT protein results in increased metabolism of Cytidine Diphosphate Diglycerides]] which results in increased abundance of Cytidine Monophosphate CTD PMID:2579070 NCBI chr 1:198,409,186...198,413,497
Ensembl chr 1:198,409,360...198,413,497
JBrowse link
3,N(4)-ethenocytosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mbd4 methyl-CpG binding domain 4 DNA glycosylase affects glycosylation ISO MBD4 protein affects the glycosylation of 3,N(4)-ethenocytosine CTD PMID:11056019 NCBI chr 4:147,744,673...147,756,462
Ensembl chr 4:147,746,186...147,756,294
JBrowse link
G Tdg thymine-DNA glycosylase increases metabolic processing ISO TDG protein results in increased metabolism of 3,N(4)-ethenocytosine CTD PMID:10626224 NCBI chr 7:27,194,000...27,213,676
Ensembl chr 7:27,193,998...27,214,236
JBrowse link
4,6-diamino-5-formamidopyrimidine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Neil1 nei-like DNA glycosylase 1 affects metabolic processing ISO NEIL1 protein affects the metabolism of 4,6-diamino-5-N-formamidopyrimidine CTD PMID:17389588 NCBI chr 8:61,817,258...61,824,023
Ensembl chr 8:61,817,258...61,823,102
JBrowse link
5-(hydroxymethyl)cytosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atm ATM serine/threonine kinase decreases methylation ISO 5-hydroxymethylcytosine results in decreased methylation of ATM gene CTD PMID:30990028 NCBI chr 8:58,015,938...58,119,973
Ensembl chr 8:58,015,940...58,120,045
JBrowse link
G Cmahp cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene multiple interactions ISO [bisphenol A results in decreased methylation of CMAH intron] which results in decreased abundance of 5-hydroxymethylcytosine CTD PMID:30044229 NCBI chr17:42,567,472...42,640,221
Ensembl chr17:42,583,945...42,640,221
JBrowse link
G Dnmt1 DNA methyltransferase 1 multiple interactions ISO DNMT1 protein promotes the reaction [bis(4-hydroxyphenyl)sulfone results in decreased abundance of 5-hydroxymethylcytosine]; DNMT1 protein promotes the reaction [bisphenol A results in decreased abundance of 5-hydroxymethylcytosine] CTD PMID:32105160 NCBI chr 8:21,922,515...21,968,495
Ensembl chr 8:21,922,515...21,968,495
JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha multiple interactions ISO DNMT3A protein promotes the reaction [bis(4-hydroxyphenyl)sulfone results in decreased abundance of 5-hydroxymethylcytosine]; DNMT3A protein promotes the reaction [bisphenol A results in decreased abundance of 5-hydroxymethylcytosine] CTD PMID:32105160 NCBI chr 6:28,205,375...28,346,052
Ensembl chr 6:28,235,695...28,340,577
JBrowse link
G Esr1 estrogen receptor 1 decreases abundance
multiple interactions
ISO ESR1 protein results in decreased abundance of 5-hydroxymethylcytosine
ESR1 protein promotes the reaction [bis(4-hydroxyphenyl)sulfone results in decreased abundance of 5-hydroxymethylcytosine]; ESR1 protein promotes the reaction [bisphenol A results in decreased abundance of 5-hydroxymethylcytosine]
CTD PMID:32105160 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Ftl1 ferritin light chain 1 multiple interactions ISO [Chloranil results in increased abundance of 5-hydroxymethylcytosine] which results in increased expression of FTL mRNA CTD PMID:24214992 NCBI chr 1:101,448,190...101,450,034
Ensembl chr 1:101,448,346...101,449,829
JBrowse link
G Gnas GNAS complex locus multiple interactions ISO [bisphenol A results in increased methylation of GNAS intron] which results in increased abundance of 5-hydroxymethylcytosine CTD PMID:30044229 NCBI chr 3:172,374,957...172,434,988
Ensembl chr 3:172,374,957...172,428,483
Ensembl chr 3:172,374,957...172,428,483
JBrowse link
G Grb10 growth factor receptor bound protein 10 multiple interactions ISO [bisphenol A results in increased methylation of GRB10 intron] which results in increased abundance of 5-hydroxymethylcytosine CTD PMID:30044229 NCBI chr14:92,021,851...92,122,249
Ensembl chr14:92,021,851...92,117,923
JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 decreases abundance ISO IDH2 protein mutant form results in decreased abundance of 5-hydroxymethylcytosine CTD PMID:27469509 NCBI chr 1:141,874,354...141,893,674
Ensembl chr 1:141,866,283...141,893,705
JBrowse link
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 multiple interactions ISO [bisphenol A results in decreased methylation of KCNQ1 intron] which results in decreased abundance of 5-hydroxymethylcytosine CTD PMID:30044229 NCBI chr 1:216,293,087...216,630,339
Ensembl chr 1:216,293,087...216,630,339
JBrowse link
G Klf14 Kruppel-like factor 14 multiple interactions ISO [bisphenol A results in decreased methylation of KLF14 exon] which results in decreased abundance of 5-hydroxymethylcytosine CTD PMID:30044229 NCBI chr 4:58,247,876...58,250,798
Ensembl chr 4:58,247,876...58,250,798
JBrowse link
G Pde10a phosphodiesterase 10A multiple interactions ISO [bisphenol A results in increased methylation of PDE10A intron] which results in increased abundance of 5-hydroxymethylcytosine CTD PMID:30044229 NCBI chr 1:52,360,296...52,544,448
Ensembl chr 1:52,360,296...52,544,450
JBrowse link
G Pde4d phosphodiesterase 4D multiple interactions ISO [bisphenol A results in increased methylation of PDE4D exon] which results in increased abundance of 5-hydroxymethylcytosine CTD PMID:30044229 NCBI chr 2:40,219,999...41,468,551
Ensembl chr 2:40,554,146...41,464,264
JBrowse link
G Plagl1 PLAG1 like zinc finger 1 multiple interactions ISO [bisphenol A results in increased methylation of PLAGL1 exon] which results in increased abundance of 5-hydroxymethylcytosine CTD PMID:30044229 NCBI chr 1:7,219,587...7,270,169
Ensembl chr 1:7,252,349...7,259,035
JBrowse link
G Ppp1r9a protein phosphatase 1, regulatory subunit 9A multiple interactions ISO [bisphenol A results in decreased methylation of PPP1R9A intron] which results in decreased abundance of 5-hydroxymethylcytosine CTD PMID:30044229 NCBI chr 4:29,976,485...30,247,371
Ensembl chr 4:29,978,739...30,241,911
JBrowse link
G Tet1 tet methylcytosine dioxygenase 1 multiple interactions ISO TET1 protein affects the reaction [2,3,5,6-tetrachlorohydroquinone results in increased chemical synthesis of 5-hydroxymethylcytosine]; TET1 protein affects the reaction [Chloranil results in increased chemical synthesis of 5-hydroxymethylcytosine] CTD PMID:24214992 NCBI chr20:27,359,122...27,438,039
Ensembl chr20:27,366,213...27,437,427
JBrowse link
G Tet2 tet methylcytosine dioxygenase 2 multiple interactions
increases abundance
ISO TET2 protein affects the reaction [2,3,5,6-tetrachlorohydroquinone results in increased chemical synthesis of 5-hydroxymethylcytosine]; TET2 protein affects the reaction [Chloranil results in increased chemical synthesis of 5-hydroxymethylcytosine]
TET2 protein results in increased abundance of 5-hydroxymethylcytosine
bis(4-hydroxyphenyl)sulfone promotes the reaction [TET2 protein results in increased abundance of 5-hydroxymethylcytosine]; bisphenol A promotes the reaction [TET2 protein results in increased abundance of 5-hydroxymethylcytosine]; TET2 protein inhibits the reaction [bis(4-hydroxyphenyl)sulfone results in decreased abundance of 5-hydroxymethylcytosine]; TET2 protein inhibits the reaction [bisphenol A results in decreased abundance of 5-hydroxymethylcytosine]
CTD PMID:24214992, PMID:32105160 NCBI chr 2:238,719,389...238,802,975
Ensembl chr 2:238,720,835...238,803,024
JBrowse link
G Ubc ubiquitin C multiple interactions ISO [Chloranil results in increased abundance of 5-hydroxymethylcytosine] which results in increased expression of UBC mRNA CTD PMID:24214992 NCBI chr12:36,638,457...36,642,734
Ensembl chr12:36,638,457...36,642,734
JBrowse link
5-fluorocytidine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cda cytidine deaminase increases metabolic processing ISO CDA protein results in increased metabolism of 5-fluorocytidine CTD PMID:21804305 NCBI chr 5:156,703,579...156,734,541
Ensembl chr 5:156,703,579...156,734,541
JBrowse link
5-methylcytosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tet1 tet methylcytosine dioxygenase 1 multiple interactions ISO TET1 protein affects the reaction [2,3,5,6-tetrachlorohydroquinone results in increased oxidation of 5-Methylcytosine]; TET1 protein affects the reaction [Chloranil results in increased oxidation of 5-Methylcytosine] CTD PMID:24214992 NCBI chr20:27,359,122...27,438,039
Ensembl chr20:27,366,213...27,437,427
JBrowse link
G Tet2 tet methylcytosine dioxygenase 2 multiple interactions ISO TET2 protein affects the reaction [2,3,5,6-tetrachlorohydroquinone results in increased oxidation of 5-Methylcytosine]; TET2 protein affects the reaction [Chloranil results in increased oxidation of 5-Methylcytosine] CTD PMID:24214992 NCBI chr 2:238,719,389...238,802,975
Ensembl chr 2:238,720,835...238,803,024
JBrowse link
G Wrap53 WD repeat containing, antisense to TP53 multiple interactions ISO [Pesticides results in increased methylation of WRAP53 gene] which results in increased abundance of 5-Methylcytosine CTD PMID:31243981 NCBI chr10:56,169,024...56,185,800
Ensembl chr10:56,169,025...56,185,857
JBrowse link
6-(cyclohexylmethoxy)-5-nitrosopyrimidine-2,4-diamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atr ATR serine/threonine kinase multiple interactions
decreases activity
ISO 4-cyclohexylmethoxy-5-nitrosopyrimidine-2,6-diamine inhibits the reaction [[trovafloxacin co-treated with TNF protein] results in increased phosphorylation of ATR protein]; 4-cyclohexylmethoxy-5-nitrosopyrimidine-2,6-diamine inhibits the reaction [trovafloxacin results in increased phosphorylation of ATR protein]; [4-cyclohexylmethoxy-5-nitrosopyrimidine-2,6-diamine results in decreased activity of ATR] which results in increased susceptibility to Cisplatin; [4-cyclohexylmethoxy-5-nitrosopyrimidine-2,6-diamine results in decreased activity of ATR] which results in increased susceptibility to Hydroxyurea; [4-cyclohexylmethoxy-5-nitrosopyrimidine-2,6-diamine results in decreased activity of ATR] which results in increased susceptibility to Temozolomide CTD PMID:21730979, PMID:25748550 NCBI chr 8:103,673,578...103,770,886
Ensembl chr 8:103,673,411...103,770,947
JBrowse link
G Casp7 caspase 7 multiple interactions ISO 4-cyclohexylmethoxy-5-nitrosopyrimidine-2,6-diamine promotes the reaction [1-(3-((2-(dimethylamino)ethyl)carbamoyl)phenyl)-3-(4-(bis(2-chloroethyl)amino)phenyl)urea results in increased cleavage of CASP7 protein] CTD PMID:26208482 NCBI chr 1:277,190,557...277,242,779
Ensembl chr 1:277,190,964...277,242,774
JBrowse link
G Casp8 caspase 8 multiple interactions ISO 4-cyclohexylmethoxy-5-nitrosopyrimidine-2,6-diamine promotes the reaction [1-(3-((2-(dimethylamino)ethyl)carbamoyl)phenyl)-3-(4-(bis(2-chloroethyl)amino)phenyl)urea results in increased cleavage of CASP8 protein] CTD PMID:26208482 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Casp9 caspase 9 multiple interactions ISO 4-cyclohexylmethoxy-5-nitrosopyrimidine-2,6-diamine promotes the reaction [1-(3-((2-(dimethylamino)ethyl)carbamoyl)phenyl)-3-(4-(bis(2-chloroethyl)amino)phenyl)urea results in increased cleavage of CASP9 protein] CTD PMID:26208482 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Chek1 checkpoint kinase 1 multiple interactions ISO 4-cyclohexylmethoxy-5-nitrosopyrimidine-2,6-diamine inhibits the reaction [1-(3-((2-(dimethylamino)ethyl)carbamoyl)phenyl)-3-(4-(bis(2-chloroethyl)amino)phenyl)urea results in increased phosphorylation of CHEK1 protein] CTD PMID:26208482 NCBI chr 8:39,181,162...39,201,588
Ensembl chr 8:39,181,163...39,243,882
JBrowse link
G Chek2 checkpoint kinase 2 multiple interactions ISO 4-cyclohexylmethoxy-5-nitrosopyrimidine-2,6-diamine inhibits the reaction [1-(3-((2-(dimethylamino)ethyl)carbamoyl)phenyl)-3-(4-(bis(2-chloroethyl)amino)phenyl)urea results in increased phosphorylation of CHEK2 protein] CTD PMID:26208482 NCBI chr12:51,845,574...51,878,098
Ensembl chr12:51,845,796...51,877,624
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions ISO [4-cyclohexylmethoxy-5-nitrosopyrimidine-2,6-diamine co-treated with 1-(3-((2-(dimethylamino)ethyl)carbamoyl)phenyl)-3-(4-(bis(2-chloroethyl)amino)phenyl)urea] results in increased cleavage of PARP1 protein CTD PMID:26208482 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO 4-cyclohexylmethoxy-5-nitrosopyrimidine-2,6-diamine inhibits the reaction [trovafloxacin promotes the reaction [Lipopolysaccharides results in increased expression of TNF protein]]; 4-cyclohexylmethoxy-5-nitrosopyrimidine-2,6-diamine inhibits the reaction [trovafloxacin results in increased expression of and results in increased stability of TNF mRNA]; 4-cyclohexylmethoxy-5-nitrosopyrimidine-2,6-diamine inhibits the reaction [trovafloxacin results in increased expression of TNF protein]
4-cyclohexylmethoxy-5-nitrosopyrimidine-2,6-diamine inhibits the reaction [[trovafloxacin co-treated with TNF protein] results in increased phosphorylation of ATR protein]
CTD PMID:24817034, PMID:25748550 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
annomontine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor increases expression ISO annomontine results in increased expression of AHR mRNA CTD PMID:20449727 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Ahrr aryl-hydrocarbon receptor repressor increases expression ISO annomontine results in increased expression of AHRR mRNA CTD PMID:20449727 NCBI chr 1:31,603,297...31,698,329
Ensembl chr 1:31,603,297...31,698,329
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression ISO annomontine results in increased expression of CYP1A1 mRNA CTD PMID:20449727 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
benfotiamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gclm glutamate cysteine ligase, modifier subunit multiple interactions
increases expression
ISO NFE2L2 protein affects the reaction [benphothiamine metabolite results in increased expression of GCLM mRNA]; NFE2L2 protein affects the reaction [benphothiamine results in increased expression of GCLM mRNA]
benphothiamine metabolite results in increased expression of GCLM mRNA; benphothiamine results in increased expression of GCLM mRNA
CTD PMID:29860433 NCBI chr 2:225,827,504...225,847,876
Ensembl chr 2:225,827,504...225,847,874
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions
increases expression
ISO NFE2L2 protein affects the reaction [benphothiamine results in increased expression of GSR mRNA] CTD PMID:29860433 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions
ISO benphothiamine metabolite results in increased expression of HMOX1 mRNA; benphothiamine results in increased expression of HMOX1 mRNA
benphothiamine inhibits the reaction [MAPT protein results in increased expression of HMOX1 mRNA]; NFE2L2 protein affects the reaction [benphothiamine metabolite results in increased expression of HMOX1 mRNA]; NFE2L2 protein affects the reaction [benphothiamine results in increased expression of HMOX1 mRNA]
CTD PMID:29860433 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO [benphothiamine co-treated with MAPT protein] results in decreased expression of IL1B protein CTD PMID:29860433 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Mapt microtubule-associated protein tau decreases phosphorylation
multiple interactions
ISO benphothiamine results in decreased phosphorylation of MAPT protein
[benphothiamine co-treated with MAPT protein] results in decreased expression of IL1B protein; [benphothiamine co-treated with MAPT protein] results in decreased expression of NOS2 protein; [benphothiamine co-treated with MAPT protein] results in decreased expression of PTGS2 protein; [benphothiamine co-treated with MAPT protein] results in decreased expression of RELA protein; [benphothiamine co-treated with MAPT protein] results in decreased expression of TNF protein; [benphothiamine co-treated with MAPT protein] results in increased expression of NQO1 mRNA; [benphothiamine co-treated with MAPT protein] results in increased expression of TXN mRNA; benphothiamine inhibits the reaction [MAPT protein results in decreased activity of TKT protein]; benphothiamine inhibits the reaction [MAPT protein results in decreased expression of NOS2 mRNA]; benphothiamine inhibits the reaction [MAPT protein results in decreased expression of PPARGC1A protein]; benphothiamine inhibits the reaction [MAPT protein results in decreased expression of SOD1 protein]; benphothiamine inhibits the reaction [MAPT protein results in increased expression of HMOX1 mRNA]
CTD PMID:29860433 NCBI chr10:92,289,002...92,386,517
Ensembl chr10:92,288,910...92,386,517
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 multiple interactions ISO NFE2L2 protein affects the reaction [benphothiamine metabolite results in increased expression of GCLM mRNA]; NFE2L2 protein affects the reaction [benphothiamine metabolite results in increased expression of HMOX1 mRNA]; NFE2L2 protein affects the reaction [benphothiamine metabolite results in increased expression of NQO1 mRNA]; NFE2L2 protein affects the reaction [benphothiamine results in increased expression of GCLM mRNA]; NFE2L2 protein affects the reaction [benphothiamine results in increased expression of GSR mRNA]; NFE2L2 protein affects the reaction [benphothiamine results in increased expression of HMOX1 mRNA]; NFE2L2 protein affects the reaction [benphothiamine results in increased expression of NQO1 mRNA] CTD PMID:29860433 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO [benphothiamine co-treated with MAPT protein] results in decreased expression of NOS2 protein; benphothiamine inhibits the reaction [MAPT protein results in decreased expression of NOS2 mRNA] CTD PMID:29860433 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression
multiple interactions
ISO benphothiamine metabolite results in increased expression of NQO1 mRNA; benphothiamine results in increased expression of NQO1 mRNA
[benphothiamine co-treated with MAPT protein] results in increased expression of NQO1 mRNA; NFE2L2 protein affects the reaction [benphothiamine metabolite results in increased expression of NQO1 mRNA]; NFE2L2 protein affects the reaction [benphothiamine results in increased expression of NQO1 mRNA]
CTD PMID:29860433 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha multiple interactions ISO benphothiamine inhibits the reaction [MAPT protein results in decreased expression of PPARGC1A protein] CTD PMID:29860433 NCBI chr14:63,095,291...63,190,688
Ensembl chr14:63,095,720...63,187,009
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO [benphothiamine co-treated with MAPT protein] results in decreased expression of PTGS2 protein CTD PMID:29860433 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO [benphothiamine co-treated with MAPT protein] results in decreased expression of RELA protein CTD PMID:29860433 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions ISO benphothiamine inhibits the reaction [MAPT protein results in decreased expression of SOD1 protein] CTD PMID:29860433 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
JBrowse link
G Tkt transketolase multiple interactions EXP
ISO
[benphothiamine co-treated with Streptozocin] results in increased activity of TKT protein
benphothiamine inhibits the reaction [MAPT protein results in decreased activity of TKT protein]
CTD PMID:12592403, PMID:29860433 NCBI chr16:6,609,670...6,634,608
Ensembl chr16:6,609,668...6,634,595
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO [benphothiamine co-treated with MAPT protein] results in decreased expression of TNF protein CTD PMID:29860433 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Txn1 thioredoxin 1 multiple interactions ISO [benphothiamine co-treated with MAPT protein] results in increased expression of TXN mRNA CTD PMID:29860433 NCBI chr 5:75,049,735...75,057,731
Ensembl chr 5:75,049,747...75,057,752
JBrowse link
bupirimate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity ISO bupirimate results in increased activity of NR1I2 protein CTD PMID:16565514, PMID:21924250 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 increases activity ISO bupirimate results in increased activity of NR1I3 protein CTD PMID:21924250 NCBI chr13:89,585,072...89,591,278
Ensembl chr13:89,586,283...89,591,277
JBrowse link
capecitabine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb7 ATP binding cassette subfamily B member 7 decreases response to substance ISO ABCB7 protein results in decreased susceptibility to Capecitabine CTD PMID:16734730 NCBI chr  X:75,150,511...75,291,950
Ensembl chr  X:75,150,608...75,291,938
JBrowse link
G Acaa1a acetyl-CoA acyltransferase 1A increases response to substance ISO ACAA1 protein results in increased susceptibility to Capecitabine CTD PMID:16734730 NCBI chr 8:128,027,880...128,036,471
Ensembl chr 8:128,027,958...128,036,236
JBrowse link
G Agpat2 1-acylglycerol-3-phosphate O-acyltransferase 2 increases response to substance ISO AGPAT2 protein results in increased susceptibility to Capecitabine CTD PMID:16734730 NCBI chr 3:4,044,741...4,055,384
Ensembl chr 3:4,044,542...4,055,806
JBrowse link
G Agr2 anterior gradient 2, protein disulphide isomerase family member increases response to substance ISO AGR2 protein results in increased susceptibility to Capecitabine CTD PMID:16734730 NCBI chr 6:55,465,782...55,487,087
Ensembl chr 6:55,465,782...55,487,714
JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B decreases response to substance ISO AKR1B1 protein results in decreased susceptibility to Capecitabine CTD PMID:16734730 NCBI chr 4:61,706,866...61,720,959
Ensembl chr 4:61,706,864...61,720,956
JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 increases response to substance ISO AKR1C3 protein results in increased susceptibility to Capecitabine CTD PMID:16734730 NCBI chr17:69,761,126...69,778,021
Ensembl chr17:69,761,118...69,778,021
JBrowse link
G Arl4d ADP-ribosylation factor like GTPase 4D decreases response to substance ISO ARL4D protein results in decreased susceptibility to Capecitabine CTD PMID:16734730 NCBI chr10:89,577,556...89,580,368
Ensembl chr10:89,578,212...89,580,368
JBrowse link
G Axl Axl receptor tyrosine kinase decreases response to substance ISO AXL protein results in decreased susceptibility to Capecitabine CTD PMID:16734730 NCBI chr 1:82,550,892...82,580,761
Ensembl chr 1:82,549,420...82,580,761
JBrowse link
G Canx calnexin multiple interactions ISO CANX results in decreased susceptibility to [Fluorouracil co-treated with Capecitabine] CTD PMID:18678097 NCBI chr10:35,800,942...35,833,939
Ensembl chr10:35,800,942...35,833,861
JBrowse link
G Ccn1 cellular communication network factor 1 decreases response to substance ISO CCN1 protein results in decreased susceptibility to Capecitabine CTD PMID:16734730 NCBI chr 2:251,529,354...251,532,312
Ensembl chr 2:251,529,354...251,532,312
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A decreases expression ISO Capecitabine results in decreased expression of CDKN2A protein CTD PMID:17904787 NCBI chr 5:107,823,323...107,832,405
Ensembl chr 5:107,823,330...107,841,175
JBrowse link
G Ces1d carboxylesterase 1D multiple interactions ISO CES1 protein results in increased hydrolysis of and results in increased activity of Capecitabine CTD PMID:15687373 NCBI chr19:15,195,514...15,239,827
Ensembl chr19:15,033,108...15,239,821
JBrowse link
G Ces2h carboxylesterase 2H multiple interactions
increases response to substance
ISO CES2 protein results in increased hydrolysis of and results in increased activity of Capecitabine
CES2 gene polymorphism results in increased susceptibility to Capecitabine
CTD PMID:15687373, PMID:18473752 NCBI chr19:37,052,555...37,067,176
Ensembl chr19:37,052,556...37,067,156
JBrowse link
G Cib1 calcium and integrin binding 1 increases response to substance ISO CIB1 protein results in increased susceptibility to Capecitabine CTD PMID:16734730 NCBI chr 1:142,014,962...142,020,461
Ensembl chr 1:142,014,958...142,020,525
JBrowse link
G Cldn3 claudin 3 increases response to substance ISO CLDN3 protein results in increased susceptibility to Capecitabine CTD PMID:16734730 NCBI chr12:21,831,341...21,832,813
Ensembl chr12:21,831,342...21,832,813
JBrowse link
G Dpyd dihydropyrimidine dehydrogenase increases expression
decreases response to substance
affects response to substance
ISO Capecitabine results in increased expression of DPYD mRNA
DPYD protein results in decreased susceptibility to Capecitabine
DPYD protein affects the susceptibility to Capecitabine
CTD PMID:16734730, PMID:17611699, PMID:18846242 NCBI chr 2:221,823,692...222,694,627
Ensembl chr 2:221,823,687...222,694,627
JBrowse link
G Dse dermatan sulfate epimerase decreases response to substance ISO DSE protein results in decreased susceptibility to Capecitabine CTD PMID:16734730 NCBI chr20:27,703,738...27,784,982
Ensembl chr20:27,703,732...27,782,586
JBrowse link
G Eps8 epidermal growth factor receptor pathway substrate 8 increases response to substance ISO EPS8 protein results in increased susceptibility to Capecitabine CTD PMID:16734730 NCBI chr 4:171,475,155...171,645,620
Ensembl chr 4:171,475,567...171,591,882
JBrowse link
G Erbb3 erb-b2 receptor tyrosine kinase 3 increases response to substance ISO ERBB3 protein results in increased susceptibility to Capecitabine CTD PMID:16734730 NCBI chr 7:2,989,202...3,010,610
Ensembl chr 7:2,989,340...3,010,350
JBrowse link
G Fhl1 four and a half LIM domains 1 decreases response to substance ISO FHL1 protein results in decreased susceptibility to Capecitabine CTD PMID:16734730 NCBI chr  X:159,112,516...159,172,528
Ensembl chr  X:159,112,880...159,172,524
JBrowse link
G Flii FLII, actin remodeling protein decreases response to substance ISO FLII protein results in decreased susceptibility to Capecitabine CTD PMID:16734730 NCBI chr10:46,955,460...46,969,468
Ensembl chr10:46,955,487...46,969,406
JBrowse link
G Fuca1 alpha-L-fucosidase 1 increases response to substance ISO FUCA1 protein results in increased susceptibility to Capecitabine CTD PMID:16734730 NCBI chr 5:154,269,296...154,286,545
Ensembl chr 5:154,269,118...154,286,544
JBrowse link
G Hdgfl3 HDGF like 3 decreases response to substance ISO HDGFL3 protein results in decreased susceptibility to Capecitabine CTD PMID:16734730 NCBI chr 1:143,702,864...143,752,060
Ensembl chr 1:143,702,853...143,751,789
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha decreases response to substance ISO HIF1A protein results in decreased susceptibility to Capecitabine CTD PMID:16734730 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Hras HRas proto-oncogene, GTPase decreases response to substance ISO HRAS protein results in decreased susceptibility to Capecitabine CTD PMID:16734730 NCBI chr 1:214,178,404...214,181,841
Ensembl chr 1:214,178,407...214,181,686
JBrowse link
G Il17rb interleukin 17 receptor B increases response to substance ISO IL17RB protein results in increased susceptibility to Capecitabine CTD PMID:16734730 NCBI chr16:6,064,287...6,077,978
Ensembl chr16:6,064,288...6,077,978
JBrowse link
G Il1r2 interleukin 1 receptor type 2 increases response to substance ISO IL1R2 protein results in increased susceptibility to Capecitabine CTD PMID:16734730 NCBI chr 9:46,840,646...46,881,241
Ensembl chr 9:46,840,992...46,881,264
JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO JUNB results in decreased susceptibility to [Fluorouracil co-treated with Capecitabine] CTD PMID:18678097 NCBI chr19:26,092,972...26,094,756
Ensembl chr19:26,092,974...26,094,756
JBrowse link
G Lgals4 galectin 4 increases response to substance ISO LGALS4 protein results in increased susceptibility to Capecitabine CTD PMID:16734730 NCBI chr 1:87,019,598...87,027,720
Ensembl chr 1:87,019,975...87,027,691
JBrowse link
G Mdm4 MDM4 regulator of p53 multiple interactions ISO MDM4 results in decreased susceptibility to [Fluorouracil co-treated with Capecitabine] CTD PMID:18678097 NCBI chr13:49,786,776...49,828,780
Ensembl chr13:49,792,794...49,828,720
JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions ISO MMP2 results in decreased susceptibility to [Fluorouracil co-treated with Capecitabine] CTD PMID:18678097 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
JBrowse link
G Mre11 MRE11 homolog, double strand break repair nuclease decreases response to substance ISO MRE11 protein results in decreased susceptibility to Capecitabine CTD PMID:16734730 NCBI chr 8:13,304,355...13,350,329
Ensembl chr 8:13,305,152...13,352,489
JBrowse link
G Myb MYB proto-oncogene, transcription factor increases response to substance ISO MYB protein results in increased susceptibility to Capecitabine CTD PMID:16734730 NCBI chr 1:16,658,178...16,690,135
Ensembl chr 1:16,659,442...16,687,817
JBrowse link
G Myrf myelin regulatory factor increases response to substance ISO MYRF protein results in increased susceptibility to Capecitabine CTD PMID:16734730 NCBI chr 1:226,260,558...226,292,650
Ensembl chr 1:226,260,558...226,292,480
JBrowse link
G Pkd2 polycystin 2, transient receptor potential cation channel decreases response to substance ISO PKD2 protein results in decreased susceptibility to Capecitabine CTD PMID:16734730 NCBI chr14:6,602,004...6,645,257
Ensembl chr14:6,602,004...6,645,257
JBrowse link
G Pkp2 plakophilin 2 increases response to substance ISO PKP2 protein results in increased susceptibility to Capecitabine CTD PMID:16734730 NCBI chr11:88,912,163...88,972,213 JBrowse link
G Plce1 phospholipase C, epsilon 1 increases response to substance ISO PLCE1 protein results in increased susceptibility to Capecitabine CTD PMID:16734730 NCBI chr 1:257,156,023...257,465,440
Ensembl chr 1:257,157,264...257,466,064
JBrowse link
G Ppa1 inorganic pyrophosphatase 1 increases response to substance ISO PPA1 protein results in increased susceptibility to Capecitabine CTD PMID:16734730 NCBI chr20:31,265,519...31,292,451
Ensembl chr20:31,265,483...31,310,674
JBrowse link
G Prkacb protein kinase cAMP-activated catalytic subunit beta decreases response to substance ISO PRKACB protein results in decreased susceptibility to Capecitabine CTD PMID:16734730 NCBI chr 2:252,602,197...252,691,886
Ensembl chr 2:252,605,307...252,691,886
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 decreases expression ISO Capecitabine results in decreased expression of PTGS2 protein CTD PMID:17904787 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Ptpn13 protein tyrosine phosphatase, non-receptor type 13 decreases response to substance ISO PTPN13 protein results in decreased susceptibility to Capecitabine CTD PMID:16734730 NCBI chr14:7,688,551...7,863,664
Ensembl chr14:7,688,551...7,863,664
JBrowse link
G Pygb glycogen phosphorylase B increases response to substance ISO PYGB protein results in increased susceptibility to Capecitabine CTD PMID:16734730 NCBI chr 3:146,581,063...146,629,504
Ensembl chr 3:146,582,752...146,634,535
JBrowse link
G Rab40b Rab40b, member RAS oncogene family increases response to substance ISO RAB40B protein results in increased susceptibility to Capecitabine CTD PMID:16734730 NCBI chr10:110,557,798...110,585,424
Ensembl chr10:110,557,729...110,585,376
JBrowse link
G Rb1 RB transcriptional corepressor 1 multiple interactions ISO RB1 results in decreased susceptibility to [Fluorouracil co-treated with Capecitabine] CTD PMID:18678097 NCBI chr15:55,081,582...55,209,060
Ensembl chr15:55,083,140...55,209,342
JBrowse link
G Rbbp4 RB binding protein 4, chromatin remodeling factor multiple interactions ISO RBBP4 results in decreased susceptibility to [Fluorouracil co-treated with Capecitabine] CTD PMID:18678097 NCBI chr 5:147,499,880...147,535,240
Ensembl chr 5:147,499,882...147,535,240
JBrowse link
G Rpa1 replication protein A1 decreases response to substance ISO RPA1 protein results in decreased susceptibility to Capecitabine CTD PMID:16734730 NCBI chr10:62,140,419...62,191,518
Ensembl chr10:62,140,419...62,191,512
JBrowse link
G Rras2 RAS related 2 decreases response to substance ISO RRAS2 protein results in decreased susceptibility to Capecitabine CTD PMID:16734730 NCBI chr 1:178,940,515...179,010,257
Ensembl chr 1:178,940,516...179,010,257
JBrowse link
G Slco2b1 solute carrier organic anion transporter family, member 2b1 multiple interactions ISO Capecitabine inhibits the reaction [SLCO2B1 protein results in increased uptake of Cascade Blue] CTD PMID:30863990 NCBI chr 1:164,623,313...164,671,612
Ensembl chr 1:164,623,599...164,671,577
JBrowse link
G Stip1 stress-induced phosphoprotein 1 decreases response to substance ISO STIP1 protein results in decreased susceptibility to Capecitabine CTD PMID:16734730 NCBI chr 1:222,274,133...222,293,139
Ensembl chr 1:222,274,133...222,293,148
JBrowse link
G Tcf7l2 transcription factor 7 like 2 multiple interactions ISO TCF7L2 results in decreased susceptibility to [Fluorouracil co-treated with Capecitabine] CTD PMID:18678097 NCBI chr 1:276,686,911...276,730,517
Ensembl chr 1:276,659,542...276,730,514
Ensembl chr 1:276,659,542...276,730,514
JBrowse link
G Tead1 TEA domain transcription factor 1 decreases response to substance ISO TEAD1 protein results in decreased susceptibility to Capecitabine CTD PMID:16734730 NCBI chr 1:177,495,500...177,714,795
Ensembl chr 1:177,495,782...177,707,061
JBrowse link
G Tff1 trefoil factor 1 increases response to substance ISO TFF1 protein results in increased susceptibility to Capecitabine CTD PMID:16734730 NCBI chr20:9,892,124...9,895,984
Ensembl chr20:9,892,124...9,895,984
JBrowse link
G Trim15 tripartite motif containing 15 increases response to substance ISO TRIM15 protein results in increased susceptibility to Capecitabine CTD PMID:16734730 NCBI chr20:2,194,293...2,203,636
Ensembl chr20:2,194,709...2,201,668
JBrowse link
G Tyms thymidylate synthetase affects expression
decreases response to substance
multiple interactions
ISO Capecitabine affects the expression of TYMS mRNA
TYMS protein results in decreased susceptibility to Capecitabine
[TYMS enhancer polymorphism co-treated with VEGFA gene SNP] affects the susceptibility to [Capecitabine co-treated with oxaliplatin]
CTD PMID:16438929, PMID:16734730, PMID:21048041 NCBI chr 9:121,918,875...121,931,564
Ensembl chr 9:121,918,947...121,931,564
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions ISO [TYMS enhancer polymorphism co-treated with VEGFA gene SNP] affects the susceptibility to [Capecitabine co-treated with oxaliplatin] CTD PMID:21048041 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
G Zfp706 zinc finger protein 706 increases response to substance ISO ZNF706 protein results in increased susceptibility to Capecitabine CTD PMID:16734730 NCBI chr 7:75,803,310...75,809,853
Ensembl chr 7:75,801,735...75,809,836
JBrowse link
CDP-choline term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 decreases expression ISO Cytidine Diphosphate Choline results in decreased expression of CASP3 protein CTD PMID:12443983 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Icam1 intercellular adhesion molecule 1 decreases expression EXP Cytidine Diphosphate Choline results in decreased expression of ICAM1 mRNA CTD PMID:16193989 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Nceh1 neutral cholesterol ester hydrolase 1 multiple interactions ISO NCEH1 protein inhibits the reaction [[Chlorpyrifos metabolite co-treated with Cytidine Diphosphate Choline] results in increased abundance of Platelet Activating Factor] CTD PMID:18164358 NCBI chr 2:112,868,834...112,932,622
Ensembl chr 2:112,868,707...112,934,953
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 decreases expression ISO Cytidine Diphosphate Choline results in decreased expression of PARP1 protein modified form CTD PMID:12443983 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Sirt1 sirtuin 1 increases expression
multiple interactions
EXP Cytidine Diphosphate Choline results in increased expression of SIRT1 protein
Cytidine Diphosphate Choline results in increased expression of and results in increased activity of SIRT1 protein
CTD PMID:23600725 NCBI chr20:26,831,971...26,851,587
Ensembl chr20:26,833,357...26,852,199
JBrowse link
ceritinib term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alk ALK receptor tyrosine kinase affects response to substance ISO ALK protein affects the susceptibility to ceritinib CTD PMID:29458018 NCBI chr 6:22,696,415...23,203,791
Ensembl chr 6:22,696,397...23,203,775
JBrowse link
G Gpt glutamic--pyruvic transaminase increases secretion ISO ceritinib results in increased secretion of GPT protein CTD PMID:29655783 NCBI chr 7:117,759,083...117,761,932
Ensembl chr 7:117,759,083...117,761,931
JBrowse link
CHIR 99021 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acadvl acyl-CoA dehydrogenase, very long chain decreases expression ISO Chir 99021 results in decreased expression of ACADVL mRNA CTD PMID:29883716 NCBI chr10:56,619,321...56,624,468
Ensembl chr10:56,619,303...56,624,526
JBrowse link
G Acan aggrecan decreases expression ISO Chir 99021 results in decreased expression of ACAN mRNA CTD PMID:32220932 NCBI chr 1:140,762,758...140,824,441
Ensembl chr 1:140,762,758...140,824,441
JBrowse link
G Afp alpha-fetoprotein increases expression ISO Chir 99021 results in increased expression of AFP mRNA CTD PMID:31711903 NCBI chr14:19,141,755...19,159,919
Ensembl chr14:19,141,755...19,159,923
JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions ISO Chir 99021 binds to and results in increased activity of AHR protein; Chir 99021 inhibits the reaction [AHR protein results in decreased expression of VIM protein] CTD PMID:26259606, PMID:27752740 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Aldh1a2 aldehyde dehydrogenase 1 family, member A2 multiple interactions ISO [Chir 99021 co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with Tretinoin] results in increased expression of ALDH1A2 mRNA; [Chir 99021 co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ALDH1A2 mRNA CTD PMID:31711903 NCBI chr 8:77,640,234...77,719,488
Ensembl chr 8:77,640,222...77,719,489
JBrowse link
G Apoa1 apolipoprotein A1 increases expression
multiple interactions
ISO Chir 99021 results in increased expression of APOA1 mRNA
4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [Chir 99021 results in increased expression of APOA1 mRNA]; [4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with Tretinoin] inhibits the reaction [Chir 99021 results in increased expression of APOA1 mRNA]
CTD PMID:31711903 NCBI chr 8:50,525,091...50,526,875
Ensembl chr 8:50,525,091...50,526,875
JBrowse link
G Bglap bone gamma-carboxyglutamate protein increases expression ISO Chir 99021 results in increased expression of BGLAP mRNA CTD PMID:32220932 NCBI chr 2:187,741,770...187,748,445
Ensembl chr 2:187,741,770...187,742,747
JBrowse link
G Cdx1 caudal type homeo box 1 increases expression
multiple interactions
ISO Chir 99021 results in increased expression of CDX1 mRNA
4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide promotes the reaction [Chir 99021 results in increased expression of CDX1 mRNA]; Tretinoin inhibits the reaction [4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide promotes the reaction [Chir 99021 results in increased expression of CDX1 mRNA]]
CTD PMID:31711903 NCBI chr18:56,337,485...56,355,477
Ensembl chr18:56,338,336...56,355,490
JBrowse link
G Ctnnb1 catenin beta 1 increases expression
affects localization
multiple interactions
ISO Chir 99021 results in increased expression of CTNNB1 protein
Chir 99021 affects the localization of CTNNB1 protein
Chir 99021 inhibits the reaction [pristimerin results in decreased expression of CTNNB1 protein]
CTD PMID:26259606, PMID:31715269, PMID:32220932 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression ISO Chir 99021 results in increased expression of CYP1A2 mRNA CTD PMID:26259606 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions
increases expression
ISO Chir 99021 results in increased expression of and results in increased activity of CYP2E1 protein
Chir 99021 results in increased expression of CYP2E1 mRNA
CTD PMID:26259606 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Eif2b5 eukaryotic translation initiation factor 2B subunit epsilon multiple interactions ISO Chir 99021 promotes the reaction [GSK3B protein affects the phosphorylation of EIF2B5 protein] CTD PMID:29883716 NCBI chr11:84,080,273...84,090,259
Ensembl chr11:84,080,273...84,090,259
JBrowse link
G Esrra estrogen related receptor, alpha increases expression ISO Chir 99021 results in increased expression of ESRRA mRNA CTD PMID:29883716 NCBI chr 1:222,168,729...222,178,842
Ensembl chr 1:222,168,730...222,178,725
JBrowse link
G Eya1 EYA transcriptional coactivator and phosphatase 1 multiple interactions ISO [Chir 99021 co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of EYA1 mRNA; Tretinoin inhibits the reaction [[Chir 99021 co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of EYA1 mRNA] CTD PMID:31711903 NCBI chr 5:4,275,728...4,495,525
Ensembl chr 5:4,373,626...4,513,142
JBrowse link
G Fbxo32 F-box protein 32 decreases expression
multiple interactions
ISO Chir 99021 results in decreased expression of FBXO32 mRNA
Chir 99021 inhibits the reaction [Dexamethasone results in increased expression of FBXO32 mRNA]
CTD PMID:21832246 NCBI chr 7:98,065,664...98,098,071
Ensembl chr 7:98,063,735...98,098,268
JBrowse link
G Fgf8 fibroblast growth factor 8 multiple interactions
increases expression
ISO 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide promotes the reaction [Chir 99021 results in increased expression of FGF8 mRNA] CTD PMID:31711903 NCBI chr 1:265,492,949...265,498,965
Ensembl chr 1:265,493,124...265,498,831
JBrowse link
G Foxa1 forkhead box A1 increases expression
multiple interactions
ISO Chir 99021 results in increased expression of FOXA1 mRNA
4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [Chir 99021 results in increased expression of FOXA1 mRNA]; [4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with Tretinoin] inhibits the reaction [Chir 99021 results in increased expression of FOXA1 mRNA]
CTD PMID:31711903 NCBI chr 6:78,516,579...78,549,669
Ensembl chr 6:78,545,804...78,549,669
JBrowse link
G Foxc2 forkhead box C2 multiple interactions ISO [Chir 99021 co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of FOXC2 mRNA; Tretinoin inhibits the reaction [[Chir 99021 co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of FOXC2 mRNA] CTD PMID:31711903 NCBI chr19:53,044,379...53,047,081
Ensembl chr19:53,044,379...53,047,081
JBrowse link
G Gata6 GATA binding protein 6 multiple interactions
increases expression
ISO 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [Chir 99021 results in increased expression of GATA6 mRNA]; [4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with Tretinoin] inhibits the reaction [Chir 99021 results in increased expression of GATA6 mRNA] CTD PMID:31711903 NCBI chr18:2,415,821...2,447,087
Ensembl chr18:2,416,552...2,446,338
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta affects phosphorylation
multiple interactions
decreases activity
ISO Chir 99021 affects the phosphorylation of GSK3B protein
Chir 99021 inhibits the reaction [1-Methyl-4-phenylpyridinium promotes the reaction [GSK3B protein binds to TFEB protein]]; Chir 99021 promotes the reaction [GSK3B protein affects the expression of PPARGC1A protein]; Chir 99021 promotes the reaction [GSK3B protein affects the phosphorylation of EIF2B5 protein]
Chir 99021 results in decreased activity of GSK3B protein
CTD PMID:27752740, PMID:29883716, PMID:30165626 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268
JBrowse link
G Hes5 hes family bHLH transcription factor 5 multiple interactions ISO [2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide co-treated with SU 5402 co-treated with Chir 99021] results in decreased expression of HES5 mRNA CTD PMID:20865013 NCBI chr 5:172,364,421...172,365,188
Ensembl chr 5:172,364,421...172,365,188
JBrowse link
G Hes7 hes family bHLH transcription factor 7 increases expression
multiple interactions
ISO Chir 99021 results in increased expression of HES7 mRNA
4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide promotes the reaction [Chir 99021 results in increased expression of HES7 mRNA]; Tretinoin inhibits the reaction [4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide promotes the reaction [Chir 99021 results in increased expression of HES7 mRNA]]
CTD PMID:31711903 NCBI chr10:55,704,485...55,710,523
Ensembl chr10:55,707,164...55,709,687
JBrowse link
G Hoxb1 homeo box B1 multiple interactions ISO [Chir 99021 co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of HOXB1 mRNA CTD PMID:31711903 NCBI chr10:84,214,358...84,215,812
Ensembl chr10:84,214,358...84,215,687
JBrowse link
G Hoxb3 homeo box B3 multiple interactions ISO [Chir 99021 co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of HOXB3 mRNA CTD PMID:31711903 NCBI chr10:84,170,629...84,196,823
Ensembl chr10:84,182,118...84,195,796
JBrowse link
G Hoxb5 homeo box B5 multiple interactions ISO 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide affects the reaction [Chir 99021 results in increased expression of HOXB5 mRNA]; Tretinoin affects the reaction [4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide affects the reaction [Chir 99021 results in increased expression of HOXB5 mRNA]] CTD PMID:31711903 NCBI chr10:84,152,152...84,154,360
Ensembl chr10:84,152,152...84,154,360
JBrowse link
G Hoxb7 homeo box B7 increases expression
multiple interactions
ISO Chir 99021 results in increased expression of HOXB7 mRNA
4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide promotes the reaction [Chir 99021 results in increased expression of HOXB7 mRNA]
CTD PMID:31711903 NCBI chr10:84,135,224...84,138,642
Ensembl chr10:84,135,116...84,138,637
JBrowse link
G Hoxb9 homeo box B9 multiple interactions ISO [Chir 99021 co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of HOXB9 mRNA CTD PMID:31711903 NCBI chr10:84,119,772...84,124,963
Ensembl chr10:84,119,884...84,123,390
JBrowse link
G Ihh Indian hedgehog signaling molecule multiple interactions
increases expression
ISO 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [Chir 99021 results in increased expression of IHH mRNA]; [4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with Tretinoin] inhibits the reaction [Chir 99021 results in increased expression of IHH mRNA] CTD PMID:31711903 NCBI chr 9:82,208,223...82,214,440
Ensembl chr 9:82,208,223...82,214,440
JBrowse link
G Lamp1 lysosomal-associated membrane protein 1 multiple interactions ISO Chir 99021 inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of LAMP1 protein] CTD PMID:30165626 NCBI chr16:81,689,576...81,714,341
Ensembl chr16:81,689,335...81,714,419
JBrowse link
G Lgr5 leucine rich repeat containing G protein coupled receptor 5 increases expression ISO Chir 99021 results in increased expression of LGR5 mRNA CTD PMID:26259606 NCBI chr 7:58,447,097...58,587,787
Ensembl chr 7:58,448,277...58,587,787
JBrowse link
G Map1lc3a microtubule-associated protein 1 light chain 3 alpha multiple interactions ISO Chir 99021 inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of MAP1LC3A protein] CTD PMID:30165626 NCBI chr 3:150,801,289...150,802,935
Ensembl chr 3:150,801,289...150,802,935
JBrowse link
G Meox1 mesenchyme homeobox 1 multiple interactions ISO [Chir 99021 co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of MEOX1 mRNA; Tretinoin inhibits the reaction [[Chir 99021 co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of MEOX1 mRNA] CTD PMID:31711903 NCBI chr10:89,797,011...89,817,009
Ensembl chr10:89,797,038...89,816,491
JBrowse link
G Mesp2 mesoderm posterior bHLH transcription factor 2 multiple interactions ISO [Chir 99021 co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of MESP2 mRNA; Tretinoin inhibits the reaction [[Chir 99021 co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of MESP2 mRNA] CTD PMID:31711903 NCBI chr 1:141,550,633...141,553,239
Ensembl chr 1:141,550,633...141,553,230
JBrowse link
G Mpp1 membrane palmitoylated protein 1 multiple interactions
increases expression
ISO 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [Chir 99021 results in increased expression of MPP1 mRNA]; [4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with Tretinoin] inhibits the reaction [Chir 99021 results in increased expression of MPP1 mRNA] CTD PMID:31711903 NCBI chr 1:148,450,213...148,458,945 JBrowse link
G Msgn1 mesogenin 1 increases expression
multiple interactions
ISO Chir 99021 results in increased expression of MSGN1 mRNA
4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide promotes the reaction [Chir 99021 results in increased expression of MSGN1 mRNA]; Tretinoin inhibits the reaction [4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide promotes the reaction [Chir 99021 results in increased expression of MSGN1 mRNA]]
CTD PMID:31711903 NCBI chr 6:36,876,165...36,876,805
Ensembl chr 6:36,876,165...36,876,805
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor increases expression ISO Chir 99021 results in increased expression of MYC protein CTD PMID:25897075 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
JBrowse link
G Nanog Nanog homeobox decreases expression ISO Chir 99021 results in decreased expression of NANOG mRNA CTD PMID:31711903 NCBI chr 4:155,531,906...155,539,268
Ensembl chr 4:155,531,906...155,539,268
JBrowse link
G Nes nestin multiple interactions ISO [2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide co-treated with SU 5402 co-treated with Chir 99021] results in decreased expression of NES mRNA CTD PMID:20865013 NCBI chr 2:187,343,109...187,352,972
Ensembl chr 2:187,344,056...187,352,969
JBrowse link
G Neurog2 neurogenin 2 multiple interactions ISO [Chir 99021 co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with Tretinoin] results in increased expression of NEUROG2 mRNA CTD PMID:31711903 NCBI chr 2:231,962,517...231,963,441
Ensembl chr 2:231,962,517...231,963,308
JBrowse link
G Nodal nodal growth differentiation factor multiple interactions
increases expression
ISO 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [Chir 99021 results in increased expression of NODAL mRNA]; [4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with Tretinoin] inhibits the reaction [Chir 99021 results in increased expression of NODAL mRNA] CTD PMID:31711903 NCBI chr20:31,035,729...31,044,096
Ensembl chr20:31,035,729...31,044,096
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO Chir 99021 binds to and results in increased activity of NR1I2 protein CTD PMID:26259606 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
JBrowse link
G Nrf1 nuclear respiratory factor 1 decreases expression ISO Chir 99021 results in decreased expression of NRF1 mRNA CTD PMID:29883716 NCBI chr 4:57,335,732...57,445,317
Ensembl chr 4:57,378,069...57,445,341
JBrowse link
G Olig3 oligodendrocyte transcription factor 3 multiple interactions ISO [Chir 99021 co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with Tretinoin] results in increased expression of OLIG3 mRNA CTD PMID:31711903 NCBI chr 1:14,797,766...14,799,835
Ensembl chr 1:14,797,766...14,799,835
JBrowse link
G Pax3 paired box 3 multiple interactions ISO [Chir 99021 co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with Tretinoin] results in increased expression of PAX3 mRNA; [Chir 99021 co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PAX3 mRNA CTD PMID:31711903 NCBI chr 9:84,004,004...84,101,226
Ensembl chr 9:84,005,183...84,101,172
JBrowse link
G Pax6 paired box 6 multiple interactions
increases expression
ISO [4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with Tretinoin] promotes the reaction [Chir 99021 results in increased expression of PAX6 mRNA] CTD PMID:31711903 NCBI chr 3:95,700,241...95,728,682
Ensembl chr 3:95,707,386...95,728,624
JBrowse link
G Perm1 PPARGC1 and ESRR induced regulator, muscle 1 increases expression ISO Chir 99021 results in increased expression of PERM1 mRNA CTD PMID:29883716 NCBI chr 5:173,640,780...173,646,073
Ensembl chr 5:173,640,780...173,646,073
JBrowse link
G Pou5f1 POU class 5 homeobox 1 decreases expression ISO Chir 99021 results in decreased expression of POU5F1 mRNA CTD PMID:31711903 NCBI chr20:3,747,231...3,751,994
Ensembl chr20:3,747,221...3,751,994
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha decreases expression ISO Chir 99021 results in decreased expression of PPARA mRNA CTD PMID:29883716 NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752
JBrowse link
G Ppard peroxisome proliferator-activated receptor delta decreases expression ISO Chir 99021 results in decreased expression of PPARD mRNA CTD PMID:29883716 NCBI chr20:7,818,289...7,883,482
Ensembl chr20:7,818,289...7,885,333
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha multiple interactions
increases expression
ISO Chir 99021 promotes the reaction [GSK3B protein affects the expression of PPARGC1A protein]
Chir 99021 results in increased expression of PPARGC1A mRNA; Chir 99021 results in increased expression of PPARGC1A protein
CTD PMID:29883716 NCBI chr14:63,095,291...63,190,688
Ensembl chr14:63,095,720...63,187,009
JBrowse link
G Rictor RPTOR independent companion of MTOR, complex 2 increases expression ISO Chir 99021 results in increased expression of RICTOR protein CTD PMID:25897075 NCBI chr 2:56,013,898...56,105,818
Ensembl chr 2:56,052,643...56,101,803
JBrowse link
G Runx2 RUNX family transcription factor 2 increases expression ISO Chir 99021 results in increased expression of RUNX2 mRNA CTD PMID:32220932 NCBI chr 9:18,564,743...18,773,092
Ensembl chr 9:18,564,927...18,773,092
JBrowse link
G Sox17 SRY-box transcription factor 17 multiple interactions
increases expression
ISO 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [Chir 99021 results in increased expression of SOX17 mRNA]; [4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with Tretinoin] inhibits the reaction [Chir 99021 results in increased expression of SOX17 mRNA] CTD PMID:31711903 NCBI chr 5:14,890,318...14,895,907
Ensembl chr 5:14,890,408...14,895,907
JBrowse link
G Sox2 SRY-box transcription factor 2 decreases expression
multiple interactions
ISO Chir 99021 results in decreased expression of SOX2 mRNA
[4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with Tretinoin] inhibits the reaction [Chir 99021 results in decreased expression of SOX2 mRNA]
CTD PMID:31711903 NCBI chr 2:121,165,137...121,167,545
Ensembl chr 2:121,165,137...121,167,545
JBrowse link
G Sox9 SRY-box transcription factor 9 decreases expression ISO Chir 99021 results in decreased expression of SOX9 mRNA CTD PMID:32220932 NCBI chr10:101,288,528...101,294,030
Ensembl chr10:101,288,489...101,293,379
JBrowse link
G Sp7 Sp7 transcription factor increases expression
affects localization
ISO Chir 99021 results in increased expression of SP7 mRNA
Chir 99021 affects the localization of SP7 protein
CTD PMID:32220932 NCBI chr 7:143,957,316...143,967,488
Ensembl chr 7:143,958,858...143,967,484
JBrowse link
G Sqstm1 sequestosome 1 multiple interactions ISO Chir 99021 inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of SQSTM1 protein] CTD PMID:30165626 NCBI chr10:35,704,728...35,716,316
Ensembl chr10:35,704,730...35,716,294
JBrowse link
G Syp synaptophysin multiple interactions ISO [2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide co-treated with SU 5402 co-treated with Chir 99021] results in decreased expression of SYP mRNA CTD PMID:20865013 NCBI chr  X:15,694,699...15,709,244
Ensembl chr  X:15,695,566...15,707,436
JBrowse link
G Tbx1 T-box transcription factor 1 multiple interactions
increases expression
ISO 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide promotes the reaction [Chir 99021 results in increased expression of BRACHYURY mRNA]; [Chir 99021 co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with Tretinoin] results in increased expression of BRACHYURY mRNA CTD PMID:31711903 NCBI chr11:86,552,022...86,561,647
Ensembl chr11:86,552,022...86,560,969
JBrowse link
G Tbx6 T-box transcription factor 6 increases expression
multiple interactions
ISO Chir 99021 results in increased expression of TBX6 mRNA
4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide promotes the reaction [Chir 99021 results in increased expression of TBX6 mRNA]; Tretinoin inhibits the reaction [4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide promotes the reaction [Chir 99021 results in increased expression of TBX6 mRNA]]
CTD PMID:31711903 NCBI chr 1:198,214,797...198,218,706
Ensembl chr 1:198,214,797...198,218,706
JBrowse link
G Tcf15 transcription factor 15 multiple interactions ISO [Chir 99021 co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with Tretinoin] results in increased expression of TCF15 mRNA; [Chir 99021 co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TCF15 mRNA CTD PMID:31711903 NCBI chr 3:147,643,250...147,649,511
Ensembl chr 3:147,643,250...147,649,504
JBrowse link
G Tfeb transcription factor EB multiple interactions ISO Chir 99021 affects the reaction [1-Methyl-4-phenylpyridinium affects the localization of TFEB protein]; Chir 99021 inhibits the reaction [1-Methyl-4-phenylpyridinium promotes the reaction [GSK3B protein binds to TFEB protein]]; Chir 99021 inhibits the reaction [1-Methyl-4-phenylpyridinium promotes the reaction [YWHAQ protein binds to TFEB protein]] CTD PMID:30165626 NCBI chr 9:15,208,141...15,264,101
Ensembl chr 9:15,207,822...15,214,596
JBrowse link
G Tubb3 tubulin, beta 3 class III multiple interactions ISO [2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide co-treated with SU 5402 co-treated with Chir 99021] results in decreased expression of TUBB3 mRNA CTD PMID:20865013 NCBI chr19:56,220,759...56,229,813
Ensembl chr19:56,220,755...56,229,813
JBrowse link
G Uncx UNC homeobox multiple interactions ISO [Chir 99021 co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of UNCX mRNA; Tretinoin inhibits the reaction [[Chir 99021 co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of UNCX mRNA] CTD PMID:31711903 NCBI chr12:17,182,158...17,186,679
Ensembl chr12:17,182,163...17,186,679
JBrowse link
G Vim vimentin multiple interactions ISO Chir 99021 inhibits the reaction [AHR protein results in decreased expression of VIM protein] CTD PMID:27752740 NCBI chr17:80,882,715...80,891,200
Ensembl chr17:80,882,666...80,891,212
JBrowse link
G Wnt3a Wnt family member 3A increases expression
multiple interactions
ISO Chir 99021 results in increased expression of WNT3A mRNA
4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide promotes the reaction [Chir 99021 results in increased expression of WNT3A mRNA]; [Chir 99021 co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with Tretinoin] results in increased expression of WNT3A mRNA
CTD PMID:31711903 NCBI chr10:45,598,898...45,643,151
Ensembl chr10:45,598,912...45,638,035
JBrowse link
G Wnt5a Wnt family member 5A increases expression
multiple interactions
ISO Chir 99021 results in increased expression of WNT5A mRNA
[Chir 99021 co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with Tretinoin] results in increased expression of WNT5A mRNA; [Chir 99021 co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of WNT5A mRNA
CTD PMID:31711903 NCBI chr16:4,469,451...4,490,271
Ensembl chr16:4,469,468...4,489,860
JBrowse link
G Ywhaq tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta multiple interactions ISO Chir 99021 inhibits the reaction [1-Methyl-4-phenylpyridinium promotes the reaction [YWHAQ protein binds to TFEB protein]] CTD PMID:30165626 NCBI chr 6:43,463,294...43,493,816
Ensembl chr 6:43,463,294...43,493,816
JBrowse link
CMP-N-acetyl-beta-neuraminic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cmas cytidine monophosphate N-acetylneuraminic acid synthetase affects abundance ISO CMAS protein affects the abundance of Cytidine Monophosphate N-Acetylneuraminic Acid CTD PMID:27380425 NCBI chr 4:176,994,129...177,012,445
Ensembl chr 4:176,994,129...177,012,444
JBrowse link
co-trimoxazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ins2 insulin 2 increases secretion ISO Trimethoprim, Sulfamethoxazole Drug Combination results in increased secretion of INS protein modified form CTD PMID:14714756 NCBI chr 1:215,856,967...215,858,034
Ensembl chr 1:215,856,971...215,858,034
JBrowse link
CTP term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor multiple interactions EXP Cytidine Triphosphate affects the folding of [Tetrachlorodibenzodioxin binds to AHR protein] CTD PMID:1848756 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G App amyloid beta precursor protein increases secretion ISO Cytidine Triphosphate results in increased secretion of APP protein modified form CTD PMID:22906069 NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858
JBrowse link
cyprodinil term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor multiple interactions
increases activity
decreases expression
affects localization
ISO
EXP
cyprodinil binds to and results in increased activity of AHR protein
cyprodinil results in increased activity of AHR protein
cyprodinil results in decreased expression of AHR protein
AHR protein affects the reaction [cyprodinil results in increased expression of CYP1A1 protein]
cyprodinil affects the localization of AHR protein
CTD PMID:23228475, PMID:23436777, PMID:28728110 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Aif1 allograft inflammatory factor 1 multiple interactions ISO [cyprodinil co-treated with mepanipyrim co-treated with pyrimethanil] promotes the reaction [[APP gene mutant form results in increased expression of APP protein modified form] which results in increased expression of AIF1 protein]
[cyprodinil co-treated with mepanipyrim co-treated with pyrimethanil] results in increased expression of AIF1 protein
CTD PMID:31939705 NCBI chr20:5,161,350...5,167,176
Ensembl chr20:5,161,333...5,166,448
JBrowse link
G App amyloid beta precursor protein affects binding
multiple interactions
ISO cyprodinil binds to APP protein modified form
[APP gene mutant form results in increased expression of APP protein modified form] which results in increased susceptibility to cyprodinil; [cyprodinil co-treated with mepanipyrim co-treated with pyrimethanil] promotes the reaction [[APP gene mutant form results in increased expression of APP protein modified form] which results in increased expression of AIF1 protein]; [cyprodinil co-treated with mepanipyrim co-treated with pyrimethanil] promotes the reaction [[APP gene mutant form results in increased expression of APP protein modified form] which results in increased expression of GFAP protein]; [cyprodinil co-treated with mepanipyrim co-treated with pyrimethanil] promotes the reaction [[APP gene mutant form results in increased expression of APP protein modified form] which results in increased expression of IL1B protein]; [cyprodinil co-treated with mepanipyrim co-treated with pyrimethanil] promotes the reaction [[APP gene mutant form results in increased expression of APP protein modified form] which results in increased expression of IL6 protein]; APP protein modified form results in increased susceptibility to [cyprodinil co-treated with mepanipyrim co-treated with pyrimethanil]
CTD PMID:31939705 NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858
JBrowse link
G Ar androgen receptor affects binding
increases activity
multiple interactions
increases expression
ISO cyprodinil binds to AR protein
cyprodinil results in increased activity of AR protein
cyprodinil inhibits the reaction [Dihydrotestosterone results in increased activity of AR protein]; cyprodinil inhibits the reaction [Dihydrotestosterone results in increased expression of AR mRNA]
cyprodinil results in increased expression of AR mRNA
CTD PMID:21310686, PMID:23436777, PMID:28728110, PMID:28803809 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Arnt aryl hydrocarbon receptor nuclear translocator multiple interactions ISO ARNT protein affects the reaction [cyprodinil results in increased expression of CYP1A1 protein] CTD PMID:23228475 NCBI chr 2:196,594,178...196,651,486
Ensembl chr 2:196,594,303...196,651,179
JBrowse link
G Bace1 beta-secretase 1 multiple interactions ISO [cyprodinil co-treated with mepanipyrim co-treated with pyrimethanil] results in increased expression of BACE1 protein CTD PMID:31939705 NCBI chr 8:50,140,092...50,162,388
Ensembl chr 8:50,139,997...50,162,361
JBrowse link
G Casp3 caspase 3 increases expression
multiple interactions
ISO cyprodinil results in increased expression of CASP3 mRNA
[pyrimethanil co-treated with cyprodinil co-treated with fludioxonil] results in increased expression of CASP3 mRNA
CTD PMID:22880100 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Ccnd1 cyclin D1 multiple interactions
increases expression
ISO fulvestrant inhibits the reaction [cyprodinil results in increased expression of CCND1 protein] CTD PMID:26344002 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Ccne1 cyclin E1 increases expression
multiple interactions
ISO cyprodinil results in increased expression of CCNE1 protein
fulvestrant inhibits the reaction [cyprodinil results in increased expression of CCNE1 protein]
CTD PMID:26344002 NCBI chr 1:94,485,830...94,495,112
Ensembl chr 1:94,485,832...94,494,980
JBrowse link
G Ctsd cathepsin D increases expression
multiple interactions
ISO cyprodinil results in increased expression of CTSD protein
fulvestrant inhibits the reaction [cyprodinil results in increased expression of CTSD protein]
CTD PMID:26344002 NCBI chr 1:215,541,570...215,553,446
Ensembl chr 1:215,541,542...215,553,451
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
increases expression
ISO 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [cyprodinil results in increased expression of CYP1A1 protein]; Dexamethasone inhibits the reaction [cyprodinil results in increased expression of CYP1A1 protein]
cyprodinil results in increased expression of CYP1A1 mRNA; cyprodinil results in increased expression of CYP1A1 protein
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [cyprodinil results in increased expression of CYP1A1 mRNA]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [cyprodinil results in increased expression of CYP1A1 protein]; AHR protein affects the reaction [cyprodinil results in increased expression of CYP1A1 protein]; ARNT protein affects the reaction [cyprodinil results in increased expression of CYP1A1 protein]
CTD PMID:23228475 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Esr1 estrogen receptor 1 affects binding ISO cyprodinil binds to ESR1 protein CTD PMID:27999363 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Gfap glial fibrillary acidic protein multiple interactions ISO [cyprodinil co-treated with mepanipyrim co-treated with pyrimethanil] promotes the reaction [[APP gene mutant form results in increased expression of APP protein modified form] which results in increased expression of GFAP protein]
[cyprodinil co-treated with mepanipyrim co-treated with pyrimethanil] results in increased expression of GFAP protein
CTD PMID:31939705 NCBI chr10:90,990,762...90,999,435
Ensembl chr10:90,990,762...90,999,506
JBrowse link
G Gpx1 glutathione peroxidase 1 affects expression
multiple interactions
ISO cyprodinil affects the expression of GPX1 mRNA
[pyrimethanil co-treated with cyprodinil co-treated with fludioxonil] results in increased expression of GPX1 mRNA
CTD PMID:22880100 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522
JBrowse link
G H2ax H2A.X variant histone increases phosphorylation
multiple interactions
ISO cyprodinil results in increased phosphorylation of H2AX protein
[fludioxonil co-treated with cyprodinil co-treated with procymidone co-treated with iprodione co-treated with cyhalothrin] results in increased phosphorylation of H2AX protein
CTD PMID:22389207 NCBI chr 8:48,665,652...48,666,981
Ensembl chr 8:48,665,652...48,666,981
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO [cyprodinil co-treated with mepanipyrim co-treated with pyrimethanil] promotes the reaction [[APP gene mutant form results in increased expression of APP protein modified form] which results in increased expression of IL1B protein] CTD PMID:31939705 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il6 interleukin 6 multiple interactions ISO [cyprodinil co-treated with mepanipyrim co-treated with pyrimethanil] promotes the reaction [[APP gene mutant form results in increased expression of APP protein modified form] which results in increased expression of IL6 protein] CTD PMID:31939705 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation ISO cyprodinil results in increased phosphorylation of MAPK1 protein CTD PMID:23228475 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation ISO cyprodinil results in increased phosphorylation of MAPK3 protein CTD PMID:23228475 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions
increases activity
ISO [procymidone co-treated with iprodione co-treated with cyprodinil co-treated with fludioxonil co-treated with cyhalothrin] results in increased activity of NR1I2 protein
cyprodinil results in increased activity of NR1I2 protein
CTD PMID:25028461, PMID:28728110 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
JBrowse link
G Pcna proliferating cell nuclear antigen increases expression ISO cyprodinil results in increased expression of PCNA protein CTD PMID:26344002 NCBI chr 3:124,880,698...124,884,570
Ensembl chr 3:124,880,698...124,884,570
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO [cyprodinil binds to and results in decreased activity of PTGS2 protein] which results in decreased chemical synthesis of and results in decreased secretion of Prostaglandin D2 CTD PMID:26359731 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
cytarabine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A affects response to substance
increases expression
ISO ABCB1 protein affects the susceptibility to Cytarabine
Cytarabine results in increased expression of ABCB1
CTD PMID:11573427, PMID:17852453 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 affects response to substance ISO ABCC1 protein affects the susceptibility to Cytarabine CTD PMID:17852453 NCBI chr10:549,537...672,235
Ensembl chr10:549,883...672,196
JBrowse link
G Acap1 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1 increases expression ISO Cytarabine results in increased expression of ACAP1 mRNA CTD PMID:19194470 NCBI chr10:56,492,300...56,506,446
Ensembl chr10:56,492,300...56,506,446
JBrowse link
G Acta1 actin, alpha 1, skeletal muscle increases expression ISO Cytarabine results in increased expression of ACTA1 mRNA CTD PMID:21198554 NCBI chr19:56,674,072...56,677,084
Ensembl chr19:56,674,074...56,677,084
JBrowse link
G Actc1 actin, alpha, cardiac muscle 1 decreases expression ISO Cytarabine results in decreased expression of ACTC1 mRNA CTD PMID:21198554 NCBI chr 3:105,507,403...105,512,939
Ensembl chr 3:105,507,403...105,512,939
JBrowse link
G Adam19 ADAM metallopeptidase domain 19 decreases expression ISO Cytarabine results in decreased expression of ADAM19 mRNA CTD PMID:21198554 NCBI chr10:31,146,107...31,240,582
Ensembl chr10:31,146,107...31,240,582
JBrowse link
G Adamts1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 decreases expression ISO Cytarabine results in decreased expression of ADAMTS1 mRNA CTD PMID:21198554 NCBI chr11:25,342,119...25,350,938
Ensembl chr11:25,342,126...25,350,974
JBrowse link
G Adamts9 ADAM metallopeptidase with thrombospondin type 1 motif, 9 decreases expression ISO Cytarabine results in decreased expression of ADAMTS9 mRNA CTD PMID:21198554 NCBI chr 4:124,660,254...124,860,997
Ensembl chr 4:124,660,262...124,858,250
JBrowse link
G Adgrb3 adhesion G protein-coupled receptor B3 increases expression ISO Cytarabine results in increased expression of ADGRB3 mRNA CTD PMID:21198554 NCBI chr 9:31,280,623...32,022,535
Ensembl chr 9:31,281,316...32,019,205
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing multiple interactions ISO [2,2-bis(4-glycidyloxyphenyl)propane co-treated with Cytarabine] results in decreased expression of ADIPOQ mRNA CTD PMID:23264188 NCBI chr11:81,330,845...81,344,488
Ensembl chr11:81,330,293...81,344,488
JBrowse link
G Afap1l2 actin filament associated protein 1-like 2 decreases expression ISO Cytarabine results in decreased expression of AFAP1L2 mRNA CTD PMID:21198554 NCBI chr 1:277,730,760...277,827,299
Ensembl chr 1:277,730,760...277,827,269
JBrowse link
G Ahi1 Abelson helper integration site 1 increases expression ISO Cytarabine results in increased expression of AHI1 protein alternative form CTD PMID:19379585 NCBI chr 1:16,478,127...16,601,769
Ensembl chr 1:16,478,127...16,601,769
JBrowse link
G Ahnak AHNAK nucleoprotein decreases expression ISO Cytarabine results in decreased expression of AHNAK mRNA CTD PMID:21198554 NCBI chr 1:225,184,883...225,429,638
Ensembl chr 1:225,184,939...225,215,015
JBrowse link
G Aif1l allograft inflammatory factor 1-like increases expression ISO Cytarabine results in increased expression of AIF1L mRNA CTD PMID:21198554 NCBI chr 3:9,237,944...9,262,628
Ensembl chr 3:9,237,944...9,262,628
JBrowse link
G Akr1b7 aldo-keto reductase family 1, member B7 decreases expression ISO Cytarabine results in decreased expression of AKR1B15 mRNA CTD PMID:21198554 NCBI chr 4:61,850,256...61,879,733
Ensembl chr 4:61,850,348...61,862,526
JBrowse link
G Alpk2 alpha-kinase 2 decreases expression ISO Cytarabine results in decreased expression of ALPK2 mRNA CTD PMID:21198554 NCBI chr18:60,960,009...61,072,116
Ensembl chr18:60,960,662...61,057,365
JBrowse link
G Angptl2 angiopoietin-like 2 decreases expression ISO Cytarabine results in decreased expression of ANGPTL2 mRNA CTD PMID:21198554 NCBI chr 3:12,262,822...12,292,665
Ensembl chr 3:12,262,822...12,292,663
JBrowse link
G Anks1a ankyrin repeat and sterile alpha motif domain containing 1A decreases expression ISO Cytarabine results in decreased expression of ANKS1A mRNA CTD PMID:21198554 NCBI chr20:7,484,550...7,636,498
Ensembl chr20:7,484,550...7,636,497
JBrowse link
G Ano8 anoctamin 8 increases expression ISO Cytarabine results in increased expression of ANO8 mRNA CTD PMID:21198554 NCBI chr16:19,884,661...19,894,608
Ensembl chr16:19,886,051...19,894,591
JBrowse link
G Anxa2 annexin A2 decreases expression
increases expression
ISO Cytarabine results in decreased expression of ANXA2 mRNA
Cytarabine results in increased expression of ANXA2 mRNA
CTD PMID:12165291, PMID:21198554 NCBI chr 8:75,687,134...75,723,589
Ensembl chr 8:75,687,100...75,723,594
JBrowse link
G Anxa6 annexin A6 decreases expression ISO Cytarabine results in decreased expression of ANXA6 mRNA CTD PMID:21198554 NCBI chr10:40,320,581...40,375,605
Ensembl chr10:40,320,581...40,375,605
JBrowse link
G Anxa8 annexin A8 decreases expression ISO Cytarabine results in decreased expression of ANXA8 mRNA CTD PMID:21198554 NCBI chr16:10,417,174...10,432,388
Ensembl chr16:10,417,185...10,432,393
JBrowse link
G Aplnr apelin receptor decreases expression ISO Cytarabine results in decreased expression of APLNR mRNA CTD PMID:21198554 NCBI chr 3:72,540,538...72,544,183
Ensembl chr 3:72,540,538...72,544,182
JBrowse link
G Aqp1 aquaporin 1 decreases expression ISO Cytarabine results in decreased expression of AQP1 mRNA CTD PMID:21198554 NCBI chr 4:85,551,503...85,563,683
Ensembl chr 4:85,551,502...85,569,360
JBrowse link
G Arg2 arginase 2 decreases expression ISO Cytarabine results in decreased expression of ARG2 mRNA CTD PMID:21198554 NCBI chr 6:102,311,097...102,338,406
Ensembl chr 6:102,311,116...102,338,520
JBrowse link
G Arhgap44 Rho GTPase activating protein 44 decreases expression ISO Cytarabine results in decreased expression of ARHGAP44 mRNA CTD PMID:21198554 NCBI chr10:51,501,547...51,669,546
Ensembl chr10:51,502,894...51,669,297
JBrowse link
G Arhgdib Rho GDP dissociation inhibitor beta decreases expression ISO Cytarabine results in decreased expression of ARHGDIB mRNA CTD PMID:21198554 NCBI chr 4:170,913,920...170,932,789
Ensembl chr 4:170,913,923...170,932,618
JBrowse link
G Arhgef3 Rho guanine nucleotide exchange factor 3 decreases expression ISO Cytarabine results in decreased expression of ARHGEF3 mRNA CTD PMID:21198554 NCBI chr16:2,743,714...3,026,768
Ensembl chr16:2,743,823...3,026,760
JBrowse link
G Arl6ip5 ADP-ribosylation factor like GTPase 6 interacting protein 5 increases expression ISO Cytarabine results in increased expression of ARL6IP5 protein CTD PMID:16430862 NCBI chr 4:129,574,363...129,598,240
Ensembl chr 4:129,574,264...129,598,915
JBrowse link
G Art4 ADP-ribosyltransferase 4 decreases expression ISO Cytarabine results in decreased expression of ART4 mRNA CTD PMID:21198554 NCBI chr 4:170,830,851...170,841,187
Ensembl chr 4:170,830,851...170,841,187
JBrowse link
G Art5 ADP-ribosyltransferase 5 decreases expression ISO Cytarabine results in decreased expression of ART5 mRNA CTD PMID:21198554 NCBI chr 1:167,192,809...167,202,767
Ensembl chr 1:167,192,810...167,202,767
JBrowse link
G Atf3 activating transcription factor 3 decreases expression ISO Cytarabine results in decreased expression of ATF3 mRNA CTD PMID:21198554 NCBI chr13:109,817,892...109,849,632
Ensembl chr13:109,817,728...109,849,632
JBrowse link
G Atl1 atlastin GTPase 1 increases expression ISO Cytarabine results in increased expression of ATL1 mRNA CTD PMID:21198554 NCBI chr 6:92,229,764...92,370,428
Ensembl chr 6:92,229,686...92,370,421
JBrowse link
G Atn1 atrophin 1 increases expression ISO Cytarabine results in increased expression of ATN1 mRNA CTD PMID:21198554 NCBI chr 4:157,267,394...157,281,199
Ensembl chr 4:157,267,901...157,274,755
Ensembl chr 9:157,267,901...157,274,755
JBrowse link
G Atp10d ATPase phospholipid transporting 10D (putative) increases expression ISO Cytarabine results in increased expression of ATP10D mRNA CTD PMID:19194470 NCBI chr14:38,475,956...38,575,937
Ensembl chr14:38,477,330...38,575,785
JBrowse link
G Atp1b1 ATPase Na+/K+ transporting subunit beta 1 decreases expression ISO Cytarabine results in decreased expression of ATP1B1 mRNA CTD PMID:21198554 NCBI chr13:82,737,161...82,757,681
Ensembl chr13:82,737,159...82,758,004
JBrowse link
G Atp7b ATPase copper transporting beta decreases expression ISO Cytarabine results in decreased expression of ATP7B mRNA CTD PMID:21198554 NCBI chr16:74,865,516...74,944,935
Ensembl chr16:74,865,516...74,945,286
JBrowse link
G Atp8b4 ATPase phospholipid transporting 8B4 (putative) decreases expression ISO Cytarabine results in decreased expression of ATP8B4 mRNA CTD PMID:21198554 NCBI chr 3:118,591,560...118,968,210
Ensembl chr 3:118,591,880...118,959,850
JBrowse link
G Axl Axl receptor tyrosine kinase decreases expression ISO Cytarabine results in decreased expression of AXL mRNA CTD PMID:21198554 NCBI chr 1:82,550,892...82,580,761
Ensembl chr 1:82,549,420...82,580,761
JBrowse link
G B2m beta-2 microglobulin increases expression ISO Cytarabine results in increased expression of B2M protein CTD PMID:11096300 NCBI chr 3:114,087,287...114,093,311
Ensembl chr 3:114,087,287...114,093,309
JBrowse link
G B4galt7 beta-1,4-galactosyltransferase 7 decreases expression ISO Cytarabine results in decreased expression of B4GALT7 mRNA CTD PMID:21198554 NCBI chr17:9,549,605...9,558,672
Ensembl chr17:9,550,028...9,558,634
JBrowse link
G Bag3 BAG cochaperone 3 decreases expression ISO Cytarabine results in decreased expression of BAG3 mRNA CTD PMID:21198554 NCBI chr 1:199,941,258...199,965,191
Ensembl chr 1:199,941,161...199,965,191
JBrowse link
G Baiap2l1 BAR/IMD domain containing adaptor protein 2 like 1 decreases expression ISO Cytarabine results in decreased expression of BAIAP2L1 mRNA CTD PMID:21198554 NCBI chr12:12,226,967...12,321,172
Ensembl chr12:12,227,010...12,321,172
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression EXP
ISO
Cytarabine results in increased expression of BAX mRNA
[Cytarabine results in increased expression of TP53 protein] which results in increased expression of BAX protein; Cytarabine results in increased expression of BAX protein
CTD PMID:10200513, PMID:15203180, PMID:16129037, PMID:17490525 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bbc3 Bcl-2 binding component 3 affects response to substance ISO BBC3 protein affects the susceptibility to Cytarabine CTD PMID:20477944 NCBI chr 1:78,261,491...78,267,802 JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
increases degradation
decreases expression
ISO [Doxorubicin co-treated with Dexamethasone co-treated with Vincristine co-treated with Cytarabine co-treated with Mercaptopurine co-treated with Methotrexate co-treated with Cyclophosphamide co-treated with Enzymes and Coenzymes] results in increased expression of BCL2 protein; BCL2 protein inhibits the reaction [Cytarabine results in increased cleavage of and results in increased activity of CASP3 protein]; BCL2 protein inhibits the reaction [Cytarabine results in increased degradation of PARP1 protein]; edelfosine promotes the reaction [Cytarabine results in decreased expression of BCL2 protein]
Cytarabine results in increased degradation of BCL2 protein
Cytarabine results in decreased expression of BCL2 mRNA; Cytarabine results in decreased expression of BCL2 protein
CTD PMID:1450413, PMID:8840993, PMID:9295281, PMID:12853972, PMID:16129037, PMID:17490525, PMID:21182165 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bcl2l1 Bcl2-like 1 multiple interactions ISO BCL2L1 protein inhibits the reaction [Cytarabine results in increased cleavage of and results in increased activity of CASP3 protein]; BCL2L1 protein inhibits the reaction [Cytarabine results in increased degradation of PARP1 protein] CTD PMID:8840993 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
JBrowse link
G Bhlhe22 basic helix-loop-helix family, member e22 increases expression ISO Cytarabine results in increased expression of BHLHE22 mRNA CTD PMID:21198554 NCBI chr 2:102,685,513...102,688,624
Ensembl chr 2:102,685,513...102,688,624
JBrowse link
G Bid BH3 interacting domain death agonist multiple interactions ISO [Cytarabine co-treated with TNFSF10 protein] results in increased expression of BID protein CTD PMID:12780785 NCBI chr 4:153,439,812...153,465,247
Ensembl chr 4:153,442,218...153,465,203
JBrowse link
G Bin2 bridging integrator 2 increases expression ISO Cytarabine results in increased expression of BIN2 mRNA CTD PMID:19194470 NCBI chr 7:142,273,832...142,304,731
Ensembl chr 7:142,273,833...142,300,382
JBrowse link
G Bmp4 bone morphogenetic protein 4 decreases expression ISO Cytarabine results in decreased expression of BMP4 mRNA CTD PMID:21198554 NCBI chr15:20,776,060...20,791,013
Ensembl chr15:20,776,054...20,822,740
JBrowse link
G Bmp5 bone morphogenetic protein 5 decreases expression ISO Cytarabine results in decreased expression of BMP5 mRNA CTD PMID:21198554 NCBI chr 8:82,669,466...82,950,273
Ensembl chr 8:82,878,941...82,950,273
JBrowse link
G Bnc1 basonuclin 1 decreases expression ISO Cytarabine results in decreased expression of BNC1 mRNA CTD PMID:21198554 NCBI chr 1:143,793,280...143,818,748
NCBI chr 1:143,869,440...143,878,077
Ensembl chr 1:143,793,064...143,818,706
JBrowse link
G Bnc2 basonuclin 2 decreases expression ISO Cytarabine results in decreased expression of BNC2 mRNA CTD PMID:21198554 NCBI chr 5:102,407,508...102,807,389
Ensembl chr 5:102,415,847...102,786,331
JBrowse link
G Bora bora, aurora kinase A activator decreases expression ISO Cytarabine results in decreased expression of BORA mRNA CTD PMID:17374387 NCBI chr15:83,442,217...83,463,737
Ensembl chr15:83,442,144...83,463,717
JBrowse link
G Bpnt2 3'(2'), 5'-bisphosphate nucleotidase 2 decreases expression ISO Cytarabine results in decreased expression of BPNT2 mRNA CTD PMID:21198554 NCBI chr17:90,191,119...90,218,013
Ensembl chr17:90,188,043...90,218,013
Ensembl chr 5:90,188,043...90,218,013
JBrowse link
G Brca2 BRCA2, DNA repair associated increases expression ISO Cytarabine results in increased expression of BRCA2 mRNA CTD PMID:19194470 NCBI chr12:503,660...544,754
Ensembl chr12:504,007...544,748
JBrowse link
G Bscl2 BSCL2 lipid droplet biogenesis associated, seipin increases expression ISO Cytarabine results in increased expression of BSCL2 mRNA CTD PMID:22003191 NCBI chr 1:225,035,956...225,046,137
Ensembl chr 1:225,037,737...225,046,040
JBrowse link
G Bst2 bone marrow stromal cell antigen 2 decreases expression ISO Cytarabine results in decreased expression of BST2 mRNA CTD PMID:21198554 NCBI chr16:19,938,781...19,942,353
Ensembl chr16:19,938,784...19,942,353
JBrowse link
G Btg2 BTG anti-proliferation factor 2 increases expression ISO Cytarabine results in increased expression of BTG2 mRNA CTD PMID:21382384 NCBI chr13:50,913,185...50,916,944
Ensembl chr13:50,913,180...50,916,982
JBrowse link
G C2cd2 C2 calcium-dependent domain containing 2 decreases expression ISO Cytarabine results in decreased expression of C2CD2 mRNA CTD PMID:21198554 NCBI chr11:38,354,746...38,420,133
Ensembl chr11:38,357,424...38,420,119
JBrowse link
G C3ar1 complement C3a receptor 1 increases expression ISO Cytarabine results in increased expression of C3AR1 mRNA CTD PMID:19194470 NCBI chr 4:155,681,767...155,691,240
Ensembl chr 4:155,684,029...155,690,869
JBrowse link
G Ca12 carbonic anhydrase 12 decreases expression ISO Cytarabine results in decreased expression of CA12 mRNA CTD PMID:21198554 NCBI chr 8:72,405,770...72,461,425
Ensembl chr 8:72,405,748...72,460,240
JBrowse link
G Cab39l calcium binding protein 39-like decreases expression ISO Cytarabine results in decreased expression of CAB39L mRNA CTD PMID:21198554 NCBI chr15:39,745,124...39,849,022
Ensembl chr15:39,759,257...39,870,208
JBrowse link
G Calb1 calbindin 1 decreases expression EXP Cytarabine results in decreased expression of CALB1 protein CTD PMID:22212197 NCBI chr 5:29,538,380...29,562,774
Ensembl chr 5:29,538,380...29,562,773
JBrowse link
G Calb2 calbindin 2 decreases expression ISO Cytarabine results in decreased expression of CALB2 mRNA CTD PMID:21198554 NCBI chr19:41,482,743...41,509,617
Ensembl chr19:41,482,728...41,509,658
JBrowse link
G Calcr calcitonin receptor increases response to substance ISO CALCR results in increased susceptibility to Cytarabine CTD PMID:21755009 NCBI chr 4:28,627,439...28,702,559
Ensembl chr 4:28,627,442...28,702,559
JBrowse link
G Camk2n1 calcium/calmodulin-dependent protein kinase II inhibitor 1 increases expression ISO Cytarabine results in increased expression of CAMK2N1 mRNA CTD PMID:21198554 NCBI chr 5:156,876,706...156,878,486
Ensembl chr 5:156,876,706...156,878,486
JBrowse link
G Capn1 calpain 1 decreases expression ISO Cytarabine results in decreased expression of CAPN1 mRNA CTD PMID:21198554 NCBI chr 1:221,346,081...221,370,965
Ensembl chr 1:221,346,066...221,370,322
JBrowse link
G Carmil1 capping protein regulator and myosin 1 linker 1 decreases expression ISO Cytarabine results in decreased expression of CARMIL1 mRNA CTD PMID:21198554 NCBI chr17:43,050,282...43,339,403
Ensembl chr17:43,050,789...43,339,403
JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity
increases expression
ISO
EXP
[Cytarabine co-treated with TNFSF10 protein] results in increased activity of CASP3 protein; BCL2 protein inhibits the reaction [Cytarabine results in increased cleavage of and results in increased activity of CASP3 protein]; BCL2L1 protein inhibits the reaction [Cytarabine results in increased cleavage of and results in increased activity of CASP3 protein]; Cytarabine results in increased cleavage of and results in increased activity of CASP3 protein
Cytarabine results in increased activity of CASP3 protein
Cytarabine results in increased expression of CASP3 protein
CTD PMID:8840993, PMID:12780785, PMID:12781215, PMID:14766721, PMID:22212197, PMID:25003661 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp8 caspase 8 multiple interactions ISO [Cytarabine co-treated with TNFSF10 protein] results in increased activity of CASP8 protein; Cytarabine promotes the reaction [TNFSF10 protein results in increased activity of CASP8 protein]; Cytarabine results in increased expression of and results in increased cleavage of CASP8 protein CTD PMID:12780785, PMID:18549619, PMID:22010212 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Cavin1 caveolae associated protein 1 decreases expression ISO Cytarabine results in decreased expression of CAVIN1 mRNA CTD PMID:21198554 NCBI chr10:88,862,513...88,874,495
Ensembl chr10:88,860,733...88,874,528
JBrowse link
G Cavin3 caveolae associated protein 3 decreases expression ISO Cytarabine results in decreased expression of CAVIN3 mRNA CTD PMID:21198554 NCBI chr 1:170,317,099...170,318,688
Ensembl chr 1:170,317,113...170,318,935
JBrowse link
G Ccdc102a coiled-coil domain containing 102A decreases expression ISO Cytarabine results in decreased expression of CCDC102A mRNA CTD PMID:21198554 NCBI chr19:10,518,822...10,535,162
Ensembl chr19:10,519,493...10,535,162
JBrowse link
G Ccdc112 coiled-coil domain containing 112 increases expression ISO Cytarabine results in increased expression of CCDC112 mRNA CTD PMID:21198554 NCBI chr18:40,220,855...40,254,845
Ensembl chr18:40,220,855...40,254,845
JBrowse link
G Ccdc15 coiled-coil domain containing 15 increases expression ISO Cytarabine results in increased expression of CCDC15 mRNA CTD PMID:21198554 NCBI chr 8:39,759,077...39,830,235
Ensembl chr 8:39,762,035...39,830,306
JBrowse link
G Cckbr cholecystokinin B receptor decreases expression ISO Cytarabine results in decreased expression of CCKBR mRNA CTD PMID:21198554 NCBI chr 1:170,262,218...170,272,298
Ensembl chr 1:170,262,156...170,272,298
JBrowse link
G Ccnd3 cyclin D3 decreases expression ISO Cytarabine results in decreased expression of CCND3 mRNA CTD PMID:21198554 NCBI chr 9:15,404,816...15,410,905
Ensembl chr 9:15,404,822...15,410,943
JBrowse link
G Ccne2 cyclin E2 increases expression ISO Cytarabine results in increased expression of CCNE2 mRNA CTD PMID:21198554 NCBI chr 5:24,434,077...24,446,406
Ensembl chr 5:24,434,872...24,446,406
JBrowse link
G Ccng1 cyclin G1 increases expression EXP Cytarabine results in increased expression of CCNG1 mRNA CTD PMID:14766721, PMID:15203180 NCBI chr10:25,903,925...25,910,298
Ensembl chr10:25,903,911...25,910,325
JBrowse link
G Cd44 CD44 molecule (Indian blood group) decreases expression ISO Cytarabine results in decreased expression of CD44 mRNA CTD PMID:21198554 NCBI chr 3:92,695,083...92,783,820
Ensembl chr 3:92,696,313...92,783,658
JBrowse link
G Cd8a CD8a molecule increases expression ISO Cytarabine results in increased expression of CD8A mRNA CTD PMID:19194470 NCBI chr 4:99,217,640...99,243,352
Ensembl chr 4:99,239,115...99,243,351
JBrowse link
G Cdc42ep5 CDC42 effector protein 5 decreases expression ISO Cytarabine results in decreased expression of CDC42EP5 mRNA CTD PMID:21198554 NCBI chr 1:73,717,207...73,719,600
Ensembl chr 1:73,719,005...73,719,529
JBrowse link
G Cdca8 cell division cycle associated 8 decreases expression ISO Cytarabine results in decreased expression of CDCA8 mRNA CTD PMID:17374387 NCBI chr 5:142,911,310...142,933,536
Ensembl chr 5:142,911,305...142,933,526
JBrowse link
G Cdh11 cadherin 11 decreases expression ISO Cytarabine results in decreased expression of CDH11 mRNA CTD PMID:21198554 NCBI chr19:2,391,181...2,551,245
Ensembl chr19:2,393,059...2,551,245
JBrowse link
G Cdh3 cadherin 3 decreases expression ISO Cytarabine results in decreased expression of CDH3 mRNA CTD PMID:21198554 NCBI chr19:38,668,957...38,719,801
Ensembl chr19:38,669,230...38,719,677
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions
increases expression
ISO
EXP
[fludarabine co-treated with Cytarabine co-treated with Docetaxel] results in increased expression of CDKN1A protein; Caffeine inhibits the reaction [Cytarabine results in increased expression of CDKN1A protein]
Cytarabine results in increased expression of CDKN1A mRNA; Cytarabine results in increased expression of CDKN1A protein
CTD PMID:9703875, PMID:14766721, PMID:15203180, PMID:17977830 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cdkn1c cyclin-dependent kinase inhibitor 1C decreases expression ISO Cytarabine results in decreased expression of CDKN1C mRNA CTD PMID:21198554 NCBI chr 1:216,661,067...216,663,791
Ensembl chr 1:216,661,080...216,663,721
JBrowse link
G Cebpd CCAAT/enhancer binding protein delta decreases expression ISO Cytarabine results in decreased expression of CEBPD mRNA CTD PMID:21198554 NCBI chr11:89,008,008...89,009,146
Ensembl chr11:89,008,008...89,009,146
JBrowse link
G Celf3 CUGBP, Elav-like family member 3 increases expression ISO Cytarabine results in increased expression of CELF3 mRNA CTD PMID:21198554 NCBI chr 2:195,716,373...195,732,872
Ensembl chr 2:195,719,543...195,730,274
JBrowse link
G Cemip cell migration inducing hyaluronidase decreases expression ISO Cytarabine results in decreased expression of CEMIP mRNA CTD PMID:21198554 NCBI chr 1:146,069,774...146,226,320
Ensembl chr 1:146,069,771...146,226,462
JBrowse link
G Chat choline O-acetyltransferase increases activity EXP Cytarabine results in increased activity of CHAT protein CTD PMID:2900045 NCBI chr16:8,576,858...8,686,131
Ensembl chr16:8,577,840...8,686,131
JBrowse link
G Chn1 chimerin 1 decreases expression ISO Cytarabine results in decreased expression of CHN1 mRNA CTD PMID:21198554 NCBI chr 3:60,512,360...60,668,413
Ensembl chr 3:60,513,077...60,611,924
JBrowse link
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 decreases expression ISO Cytarabine results in decreased expression of CITED2 mRNA CTD PMID:21198554 NCBI chr 1:12,823,363...12,825,806
Ensembl chr 1:12,823,363...12,825,786
JBrowse link
G Ckb creatine kinase B increases expression ISO Cytarabine results in increased expression of CKB mRNA CTD PMID:21198554 NCBI chr 6:136,142,956...136,145,838
Ensembl chr 6:136,142,956...136,145,837
JBrowse link
G Cks2 CDC28 protein kinase regulatory subunit 2 decreases expression ISO Cytarabine results in decreased expression of CKS2 mRNA CTD PMID:17374387 NCBI chr17:13,587,664...13,593,423
Ensembl chr17:13,587,665...13,593,423
JBrowse link
G Cldn15 claudin 15 decreases expression ISO Cytarabine results in decreased expression of CLDN15 mRNA CTD PMID:21198554 NCBI chr12:22,738,198...22,750,392
Ensembl chr12:22,738,195...22,748,860
JBrowse link
G Clec1b C-type lectin domain family 1, member B decreases expression ISO Cytarabine results in decreased expression of CLEC1B mRNA CTD PMID:21198554 NCBI chr 4:163,161,941...163,170,470
Ensembl chr 4:163,162,211...163,170,466
JBrowse link
G Cnih2 cornichon family AMPA receptor auxiliary protein 2 increases expression ISO Cytarabine results in increased expression of CNIH2 mRNA CTD PMID:21198554 NCBI chr 1:220,474,485...220,480,723
Ensembl chr 1:220,474,493...220,480,132
JBrowse link
G Cnr1 cannabinoid receptor 1 increases expression ISO Cytarabine results in increased expression of CNR1 mRNA CTD PMID:21198554 NCBI chr 5:49,307,584...49,333,064
Ensembl chr 5:49,311,030...49,333,056
JBrowse link
G Cntfr ciliary neurotrophic factor receptor increases expression ISO Cytarabine results in increased expression of CNTFR mRNA CTD PMID:21198554 NCBI chr 5:58,041,114...58,078,687
Ensembl chr 5:58,041,146...58,078,545
JBrowse link
G Cntrl centriolin increases expression ISO Cytarabine results in increased expression of CNTRL mRNA CTD PMID:21198554 NCBI chr 3:14,299,441...14,371,681
Ensembl chr 3:14,299,479...14,371,681
JBrowse link
G Cobll1 cordon-bleu WH2 repeat protein-like 1 decreases expression ISO Cytarabine results in decreased expression of COBLL1 mRNA CTD PMID:21198554 NCBI chr 3:51,137,104...51,298,956
Ensembl chr 3:51,137,076...51,297,852
JBrowse link
G Col13a1 collagen type XIII alpha 1 chain decreases expression ISO Cytarabine results in decreased expression of COL13A1 mRNA CTD PMID:21198554 NCBI chr20:31,456,502...31,598,360
Ensembl chr20:31,456,852...31,598,118
JBrowse link
G Col18a1 collagen type XVIII alpha 1 chain decreases expression ISO Cytarabine results in decreased expression of COL18A1 mRNA CTD PMID:21198554 NCBI chr20:12,225,202...12,332,858
Ensembl chr20:12,225,202...12,332,858
JBrowse link
G Col1a1 collagen type I alpha 1 chain decreases expression ISO Cytarabine results in decreased expression of COL1A1 mRNA CTD PMID:21198554 NCBI chr10:82,745,801...82,762,790
Ensembl chr10:82,745,801...82,762,789
JBrowse link
G Col1a2 collagen type I alpha 2 chain decreases expression ISO Cytarabine results in decreased expression of COL1A2 mRNA CTD PMID:21198554 NCBI chr 4:31,534,225...31,569,152
Ensembl chr 4:31,534,225...31,569,151
JBrowse link
G Col3a1 collagen type III alpha 1 chain decreases expression ISO Cytarabine results in decreased expression of COL3A1 mRNA CTD PMID:21198554 NCBI chr 9:52,023,295...52,059,221
Ensembl chr 9:52,023,295...52,059,217
JBrowse link
G Col5a1 collagen type V alpha 1 chain decreases expression ISO Cytarabine results in decreased expression of COL5A1 mRNA CTD PMID:21198554 NCBI chr 3:6,430,180...6,581,010
Ensembl chr 3:6,430,201...6,578,882
JBrowse link
G Col5a2 collagen type V alpha 2 chain decreases expression ISO Cytarabine results in decreased expression of COL5A2 mRNA CTD PMID:21198554 NCBI chr 9:52,091,088...52,238,735
Ensembl chr 9:52,092,511...52,238,564
JBrowse link
G Col6a2 collagen type VI alpha 2 chain decreases expression ISO Cytarabine results in decreased expression of COL6A2 mRNA CTD PMID:21198554 NCBI chr20:12,773,472...12,801,179
Ensembl chr20:12,773,427...12,801,180
JBrowse link
G Col6a3 collagen type VI alpha 3 chain decreases expression ISO Cytarabine results in decreased expression of COL6A3 mRNA CTD PMID:21198554 NCBI chr 9:97,926,784...98,004,643
Ensembl chr 9:97,926,787...98,004,546
JBrowse link
G Col9a1 collagen type IX alpha 1 chain increases expression ISO Cytarabine results in increased expression of COL9A1 mRNA CTD PMID:21198554 NCBI chr 9:30,419,001...30,502,307
Ensembl chr 9:30,419,001...30,502,298
JBrowse link
G Colec12 collectin sub-family member 12 decreases expression ISO Cytarabine results in decreased expression of COLEC12 mRNA CTD PMID:21198554 NCBI chr18:867,048...1,054,047
Ensembl chr18:867,048...1,052,606
JBrowse link
G Cpz carboxypeptidase Z decreases expression ISO Cytarabine results in decreased expression of CPZ mRNA CTD PMID:21198554 NCBI chr14:80,402,946...80,426,203
Ensembl chr14:80,403,001...80,426,245
JBrowse link
G Crabp1 cellular retinoic acid binding protein 1 increases expression ISO Cytarabine results in increased expression of CRABP1 mRNA CTD PMID:21198554 NCBI chr 8:59,344,097...59,352,135
Ensembl chr 8:59,344,083...59,352,132
JBrowse link
G Crispld2 cysteine-rich secretory protein LCCL domain containing 2 decreases expression ISO Cytarabine results in decreased expression of CRISPLD2 mRNA CTD PMID:21198554 NCBI chr19:52,647,038...52,705,118
Ensembl chr19:52,647,070...52,705,131
JBrowse link
G Crtap cartilage associated protein decreases expression ISO Cytarabine results in decreased expression of CRTAP mRNA CTD PMID:21198554 NCBI chr 8:122,382,613...122,402,209 JBrowse link
G Cryab crystallin, alpha B decreases expression ISO Cytarabine results in decreased expression of CRYAB mRNA CTD PMID:21198554 NCBI chr 8:55,178,543...55,182,546
Ensembl chr 8:55,178,289...55,182,545
JBrowse link
G Csnk1d casein kinase 1, delta decreases expression ISO Cytarabine results in decreased expression of CSNK1D mRNA CTD PMID:21198554 NCBI chr10:110,147,786...110,182,413
Ensembl chr10:110,148,600...110,182,408
JBrowse link
G Csrnp1 cysteine and serine rich nuclear protein 1 decreases expression ISO Cytarabine results in decreased expression of AXUD1 mRNA CTD PMID:21198554 NCBI chr 8:128,659,883...128,673,339
Ensembl chr 8:128,659,868...128,672,284
JBrowse link
G Ctsh cathepsin H decreases expression ISO Cytarabine results in decreased expression of CTSH mRNA CTD PMID:21198554 NCBI chr 8:97,439,155...97,458,293
Ensembl chr 8:97,439,161...97,458,287
JBrowse link
G Ctsl cathepsin L decreases expression ISO Cytarabine results in decreased expression of CTSL mRNA CTD PMID:21198554 NCBI chr17:1,873,105...1,879,266
Ensembl chr17:1,872,848...1,879,279
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 increases expression ISO Cytarabine results in increased expression of CXCR4 mRNA CTD PMID:19194470, PMID:21198554 NCBI chr13:45,314,952...45,318,856
Ensembl chr13:45,314,933...45,318,878
JBrowse link
G Cyb5a cytochrome b5 type A decreases expression ISO Cytarabine results in decreased expression of CYB5A mRNA CTD PMID:21198554 NCBI chr18:81,694,818...81,726,821
Ensembl chr18:81,694,808...81,726,821
JBrowse link
G Cyb5d1 cytochrome b5 domain containing 1 decreases expression ISO Cytarabine results in decreased expression of CYB5D1 mRNA CTD PMID:21198554 NCBI chr10:55,993,206...55,997,429
Ensembl chr10:55,995,823...55,997,299
JBrowse link
G Cyb5r2 cytochrome b5 reductase 2 decreases expression ISO Cytarabine results in decreased expression of CYB5R2 mRNA CTD PMID:21198554 NCBI chr 1:171,971,424...171,981,586
Ensembl chr 1:171,971,701...171,979,933
JBrowse link
G Cyba cytochrome b-245 alpha chain decreases expression ISO Cytarabine results in decreased expression of CYBA mRNA CTD PMID:21198554 NCBI chr19:55,249,634...55,257,824
Ensembl chr19:55,249,616...55,257,876
JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 decreases expression ISO Cytarabine results in decreased expression of CYP27A1 mRNA CTD PMID:21198554 NCBI chr 9:81,968,285...81,998,213
Ensembl chr 9:81,968,332...81,998,169
JBrowse link
G Cyp4x1 cytochrome P450, family 4, subfamily x, polypeptide 1 decreases expression ISO Cytarabine results in decreased expression of CYP4X1 mRNA CTD PMID:21198554 NCBI chr 5:133,929,532...133,959,447
Ensembl chr 5:133,929,532...133,959,447
JBrowse link
G Cyth1 cytohesin 1 increases expression ISO Cytarabine results in increased expression of CYTH1 mRNA CTD PMID:19194470 NCBI chr10:107,197,983...107,281,285
Ensembl chr10:107,197,989...107,281,235
JBrowse link
G Dalrd3 DALR anticodon binding domain containing 3 decreases expression ISO Cytarabine results in decreased expression of DALRD3 mRNA CTD PMID:19194470 NCBI chr 8:117,355,943...117,358,819
Ensembl chr 8:117,355,943...117,358,818
JBrowse link
G Dbn1 drebrin 1 decreases expression ISO Cytarabine results in decreased expression of DBN1 mRNA CTD PMID:19194470 NCBI chr17:9,679,511...9,693,878
Ensembl chr17:9,679,628...9,693,820
JBrowse link
G Dck deoxycytidine kinase affects binding
decreases response to substance
ISO Cytarabine binds to DCK protein
DCK gene polymorphism results in decreased susceptibility to Cytarabine
CTD PMID:1318170, PMID:18381442 NCBI chr14:20,935,442...20,952,939
Ensembl chr14:20,935,369...20,953,095
JBrowse link
G Dcn decorin decreases expression ISO Cytarabine results in decreased expression of DCN mRNA CTD PMID:21198554 NCBI chr 7:38,742,250...38,782,282
Ensembl chr 7:38,742,051...38,782,323
JBrowse link
G Ddr2 discoidin domain receptor tyrosine kinase 2 decreases expression ISO Cytarabine results in decreased expression of DDR2 mRNA CTD PMID:21198554 NCBI chr13:88,311,639...88,436,561
Ensembl chr13:88,317,145...88,436,789
JBrowse link
G Dennd1a DENN domain containing 1A increases expression ISO Cytarabine results in increased expression of DENND1A mRNA CTD PMID:19194470 NCBI chr 3:22,061,120...22,501,502
Ensembl chr 3:22,058,400...22,500,765
JBrowse link
G Deptor DEP domain containing MTOR-interacting protein decreases expression ISO Cytarabine results in decreased expression of DEPTOR mRNA CTD PMID:21198554 NCBI chr 7:94,795,161...95,000,750
Ensembl chr 7:94,795,214...94,995,809
JBrowse link
G Dhcr24 24-dehydrocholesterol reductase decreases expression ISO Cytarabine results in decreased expression of DHCR24 mRNA CTD PMID:21198554 NCBI chr 5:126,164,708...126,188,926
Ensembl chr 5:126,164,674...126,191,206
JBrowse link
G Dhfr dihydrofolate reductase increases expression ISO Cytarabine results in increased expression of DHFR mRNA CTD PMID:19194470 NCBI chr 2:21,931,887...21,958,927
Ensembl chr 2:21,931,493...21,962,453
JBrowse link
G Disp3 dispatched RND transporter family member 3 increases expression ISO Cytarabine results in increased expression of DISP3 mRNA CTD PMID:21198554 NCBI chr 5:165,051,522...165,099,826
Ensembl chr 5:165,052,871...165,083,487
JBrowse link
G Dnah2 dynein, axonemal, heavy chain 2 decreases expression ISO Cytarabine results in decreased expression of DNAH2 mRNA CTD PMID:21198554 NCBI chr10:56,029,022...56,154,602
Ensembl chr10:56,029,029...56,154,548
JBrowse link
G Dok4 docking protein 4 decreases expression ISO Cytarabine results in decreased expression of DOK4 mRNA CTD PMID:21198554 NCBI chr19:10,563,423...10,574,094
Ensembl chr19:10,563,423...10,574,093
JBrowse link
G Dsc2 desmocollin 2 decreases expression ISO Cytarabine results in decreased expression of DSC2 mRNA CTD PMID:21198554 NCBI chr18:11,826,705...11,858,801
Ensembl chr18:11,826,706...11,858,754
JBrowse link
G Dsc3 desmocollin 3 decreases expression ISO Cytarabine results in decreased expression of DSC3 mRNA CTD PMID:21198554 NCBI chr18:11,753,047...11,789,846
Ensembl chr18:11,753,047...11,789,708
JBrowse link
G Dusp4 dual specificity phosphatase 4 decreases expression ISO Cytarabine results in decreased expression of DUSP4 mRNA CTD PMID:19194470 NCBI chr16:61,080,767...61,090,973
Ensembl chr16:61,078,175...61,091,169
JBrowse link
G Edn1 endothelin 1 multiple interactions ISO EDN1 mutant form inhibits the reaction [VEGFC protein results in decreased susceptibility to Cytarabine]
EDN1 mutant form affects the reaction [VEGFC protein results in decreased susceptibility to Cytarabine]
CTD PMID:24184161 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
JBrowse link
G Eef2 eukaryotic translation elongation factor 2 decreases expression ISO Cytarabine results in decreased expression of EEF2 mRNA CTD PMID:21198554 NCBI chr 7:11,401,501...11,406,771
Ensembl chr 7:11,401,501...11,406,771
JBrowse link
G Efemp2 EGF containing fibulin extracellular matrix protein 2 decreases expression ISO Cytarabine results in decreased expression of EFEMP2 mRNA CTD PMID:21198554 NCBI chr 1:220,853,695...220,861,420
Ensembl chr 1:220,854,403...220,861,420
JBrowse link
G Efhd1 EF-hand domain family, member D1 decreases expression ISO Cytarabine results in decreased expression of EFHD1 mRNA CTD PMID:21198554 NCBI chr 9:94,362,249...94,408,884
Ensembl chr 9:94,362,299...94,408,885
JBrowse link
G Efna1 ephrin A1 decreases expression ISO Cytarabine results in decreased expression of EFNA1 mRNA CTD PMID:21198554 NCBI chr 2:188,588,808...188,596,156
Ensembl chr 2:188,588,796...188,596,222
JBrowse link
G Egfl6 EGF-like-domain, multiple 6 decreases expression ISO Cytarabine results in decreased expression of EGFL6 mRNA CTD PMID:21198554 NCBI chr  X:29,430,789...29,488,737
Ensembl chr  X:29,430,831...29,488,739
JBrowse link
G Egflam EGF-like, fibronectin type III and laminin G domains decreases expression ISO Cytarabine results in decreased expression of EGFLAM mRNA CTD PMID:21198554 NCBI chr 2:56,503,002...56,681,334
Ensembl chr 2:56,502,807...56,679,955
JBrowse link
G Eif4h eukaryotic translation initiation factor 4H decreases expression ISO Cytarabine results in decreased expression of EIF4H mRNA CTD PMID:21198554 NCBI chr12:25,093,119...25,109,805
Ensembl chr12:25,093,149...25,109,799
JBrowse link
G Eno3 enolase 3 decreases expression ISO Cytarabine results in decreased expression of ENO3 mRNA CTD PMID:21198554 NCBI chr10:57,278,271...57,283,661
Ensembl chr10:57,278,307...57,283,653
JBrowse link
G Entpd1 ectonucleoside triphosphate diphosphohydrolase 1 increases expression ISO Cytarabine results in increased expression of ENTPD1 mRNA CTD PMID:19194470 NCBI chr 1:259,692,020...259,818,922
Ensembl chr 1:259,739,955...259,819,494
JBrowse link
G Exog exo/endonuclease G decreases expression ISO Cytarabine results in decreased expression of EXOG mRNA CTD PMID:21198554 NCBI chr 8:128,133,398...128,153,110
Ensembl chr 8:128,133,431...128,153,110
JBrowse link
G Ext2 exostosin glycosyltransferase 2 decreases expression ISO Cytarabine results in decreased expression of EXT2 mRNA CTD PMID:21198554 NCBI chr 3:82,602,784...82,734,557
Ensembl chr 3:82,602,785...82,734,533
JBrowse link
G Ezr ezrin decreases expression ISO Cytarabine results in decreased expression of EZR mRNA CTD PMID:21198554 NCBI chr 1:47,287,872...47,331,412
Ensembl chr 1:47,287,874...47,331,412
JBrowse link
G F2 coagulation factor II affects expression ISO Cytarabine affects the expression of F2 protein CTD PMID:12542493 NCBI chr 3:80,529,468...80,542,993
Ensembl chr 3:80,529,428...80,543,031
JBrowse link
G Fabp7 fatty acid binding protein 7 increases expression ISO Cytarabine results in increased expression of FABP7 mRNA CTD PMID:21198554 NCBI chr20:40,769,624...40,773,156
Ensembl chr20:40,769,586...40,773,349
JBrowse link
G Fam111a family with sequence similarity 111, member A increases expression ISO Cytarabine results in increased expression of FAM111A mRNA CTD PMID:19194470 NCBI chr 1:229,003,778...229,019,532
Ensembl chr 1:229,003,961...229,019,527
JBrowse link
G Fas Fas cell surface death receptor increases expression EXP Cytarabine results in increased expression of FAS mRNA CTD PMID:14766721, PMID:15203180 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Fbln1 fibulin 1 decreases expression ISO Cytarabine results in decreased expression of FBLN1 mRNA CTD PMID:21198554 NCBI chr 7:126,096,793...126,176,468
Ensembl chr 7:126,096,793...126,176,468
JBrowse link
G Fbxo2 F-box protein 2 decreases expression ISO Cytarabine results in decreased expression of FBXO2 mRNA CTD PMID:21198554 NCBI chr 5:164,972,483...164,977,912
Ensembl chr 5:164,972,480...164,977,916
JBrowse link
G Fcgr2a Fc fragment of IgG receptor IIa increases expression ISO Cytarabine results in increased expression of FCGR2A mRNA CTD PMID:19194470 NCBI chr13:91,146,878...91,163,691
Ensembl chr13:91,168,973...91,198,036
Ensembl chr13:91,168,973...91,198,036
JBrowse link
G Flnc filamin C decreases expression ISO Cytarabine results in decreased expression of FLNC mRNA CTD PMID:21198554 NCBI chr 4:56,710,934...56,738,779
Ensembl chr 4:56,711,049...56,738,791
JBrowse link
G Flrt2 fibronectin leucine rich transmembrane protein 2 decreases expression ISO Cytarabine results in decreased expression of FLRT2 mRNA CTD PMID:21198554 NCBI chr 6:119,518,459...119,613,534
Ensembl chr 6:119,519,714...119,609,296
JBrowse link
G Fmo1 flavin containing dimethylaniline monoxygenase 1 decreases expression ISO Cytarabine results in decreased expression of FMO1 mRNA CTD PMID:21198554 NCBI chr13:80,712,885...80,745,095
Ensembl chr13:80,712,882...80,745,347
JBrowse link
G Fmo4 flavin containing dimethylaniline monoxygenase 4 decreases expression ISO Cytarabine results in decreased expression of FMO4 mRNA CTD PMID:21198554 NCBI chr13:80,685,385...80,703,575
Ensembl chr13:80,685,325...80,703,615
JBrowse link
G Frzb frizzled-related protein decreases expression ISO Cytarabine results in decreased expression of FRZB mRNA CTD PMID:21198554 NCBI chr 3:67,635,604...67,668,772
Ensembl chr 3:67,635,607...67,668,772
JBrowse link
G Fsip1 fibrous sheath interacting protein 1 increases expression ISO Cytarabine results in increased expression of FSIP1 mRNA CTD PMID:21198554 NCBI chr 3:109,877,943...110,021,186
Ensembl chr 3:109,969,152...110,021,149
JBrowse link
G Fyb2 FYN binding protein 2 decreases expression ISO Cytarabine results in decreased expression of FYB2 mRNA CTD PMID:21198554 NCBI chr 5:124,442,386...124,561,766 JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase increases expression ISO Cytarabine results in increased expression of FYN mRNA CTD PMID:21198554 NCBI chr20:44,436,354...44,630,316
Ensembl chr20:44,436,403...44,630,317
JBrowse link
G Gabarapl1 GABA type A receptor associated protein like 1 decreases expression ISO Cytarabine results in decreased expression of GABARAPL1 mRNA CTD PMID:21198554 NCBI chr 4:163,293,724...163,302,866
Ensembl chr 4:163,293,724...163,302,858
JBrowse link
G Gabrp gamma-aminobutyric acid type A receptor subunit pi increases expression ISO Cytarabine results in increased expression of GABRP mRNA CTD PMID:21198554 NCBI chr10:18,484,257...18,510,604
Ensembl chr10:18,485,514...18,506,337
JBrowse link
G Galnt10 polypeptide N-acetylgalactosaminyltransferase 10 decreases expression ISO Cytarabine results in decreased expression of GALNT10 mRNA CTD PMID:21198554 NCBI chr10:43,067,316...43,208,992
Ensembl chr10:43,067,299...43,210,427
JBrowse link
G Gap43 growth associated protein 43 increases expression ISO Cytarabine results in increased expression of GAP43 mRNA CTD PMID:21198554 NCBI chr11:58,624,198...58,717,916
Ensembl chr11:58,624,198...58,717,914
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase decreases activity
affects localization
increases response to substance
ISO Cytarabine results in decreased activity of GAPDH protein
Cytarabine affects the localization of GAPDH protein
GAPDH protein results in increased susceptibility to Cytarabine
CTD PMID:19628630 NCBI chr 4:157,676,336...157,680,322
Ensembl chr 4:157,676,595...157,679,962
JBrowse link
G Gata5 GATA binding protein 5 decreases expression ISO Cytarabine results in decreased expression of GATA5 mRNA CTD PMID:21198554 NCBI chr 3:175,701,278...175,709,465
Ensembl chr 3:175,701,280...175,709,465
JBrowse link
G Gbp4 guanylate binding protein 4 decreases expression ISO Cytarabine results in decreased expression of GBP4 mRNA CTD PMID:21198554 NCBI chr 2:248,249,232...248,263,104
Ensembl chr 2:248,249,468...248,263,168
JBrowse link
G Gca grancalcin decreases expression ISO Cytarabine results in decreased expression of GCA mRNA CTD PMID:21198554 NCBI chr 3:48,625,965...48,661,317
Ensembl chr 3:48,626,038...48,661,317
JBrowse link
G Gcnt2 glucosaminyl (N-acetyl) transferase 2 (I blood group) decreases expression ISO Cytarabine results in decreased expression of GCNT2 mRNA CTD PMID:21198554 NCBI chr17:21,634,546...21,677,477
Ensembl chr17:21,634,551...21,739,408
JBrowse link
G Ghr growth hormone receptor decreases expression ISO Cytarabine results in decreased expression of GHR mRNA CTD PMID:21198554 NCBI chr 2:53,149,225...53,413,954
Ensembl chr 2:53,150,370...53,413,638
JBrowse link
G Gls glutaminase decreases expression ISO Cytarabine results in decreased expression of GLS mRNA CTD PMID:21198554 NCBI chr 9:54,212,622...54,284,879
Ensembl chr 9:54,212,767...54,284,872
JBrowse link
G Gnb3 G protein subunit beta 3 decreases expression ISO Cytarabine results in decreased expression of GNB3 mRNA CTD PMID:21198554 NCBI chr 4:157,352,558...157,359,237
Ensembl chr 4:157,352,372...157,358,262
JBrowse link
G Gper1 G protein-coupled estrogen receptor 1 decreases expression ISO Cytarabine results in decreased expression of GPER1 mRNA CTD PMID:21198554 NCBI chr12:17,309,122...17,315,267
Ensembl chr12:17,309,834...17,311,112
JBrowse link
G Gpm6a glycoprotein m6a increases expression ISO Cytarabine results in increased expression of GPM6A mRNA CTD PMID:21198554 NCBI chr16:39,367,697...39,719,292
Ensembl chr16:39,367,692...39,719,187
JBrowse link
G Gpr19 G protein-coupled receptor 19 increases expression ISO Cytarabine results in increased expression of GPR19 mRNA CTD PMID:21198554 NCBI chr 4:168,639,930...168,668,345
Ensembl chr 4:168,639,940...168,656,673
JBrowse link
G Gpr83 G protein-coupled receptor 83 decreases expression ISO Cytarabine results in decreased expression of GPR83 mRNA CTD PMID:21198554 NCBI chr 8:13,365,583...13,376,071
Ensembl chr 8:13,365,583...13,376,070
JBrowse link
G Gprc5c G protein-coupled receptor, class C, group 5, member C decreases expression ISO Cytarabine results in decreased expression of GPRC5C mRNA CTD PMID:21198554 NCBI chr10:103,395,222...103,417,360
Ensembl chr10:103,395,511...103,417,358
JBrowse link
G Gria2 glutamate ionotropic receptor AMPA type subunit 2 increases expression ISO Cytarabine results in increased expression of GRIA2 mRNA CTD PMID:21198554 NCBI chr 2:179,584,302...179,704,629
Ensembl chr 2:179,584,308...179,704,629
JBrowse link
G Grk5 G protein-coupled receptor kinase 5 increases expression ISO Cytarabine results in increased expression of GRK5 mRNA CTD PMID:19194470 NCBI chr 1:282,265,371...282,467,842
Ensembl chr 1:282,265,370...282,462,605
JBrowse link
G Grpr gastrin releasing peptide receptor decreases expression ISO Cytarabine results in decreased expression of GRPR mRNA CTD PMID:21198554 NCBI chr  X:32,746,259...32,786,266
Ensembl chr  X:32,745,873...32,786,359
JBrowse link
G Gstcd glutathione S-transferase, C-terminal domain containing increases expression ISO Cytarabine results in increased expression of GSTCD mRNA CTD PMID:19194470 NCBI chr 2:238,109,758...238,253,326
Ensembl chr 2:238,109,490...238,253,287
JBrowse link
G Gstm1 glutathione S-transferase mu 1 affects response to substance ISO GSTM1 gene polymorphism affects the susceptibility to Cytarabine CTD PMID:15713801 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306
JBrowse link
G Gtpbp1 GTP binding protein 1 increases expression ISO Cytarabine results in increased expression of GTPBP1 mRNA CTD PMID:19194470 NCBI chr 7:120,923,274...120,947,723
Ensembl chr 7:120,923,274...120,947,723
JBrowse link
G Gucy1a1 guanylate cyclase 1 soluble subunit alpha 1 decreases expression ISO Cytarabine results in decreased expression of GUCY1A1 mRNA CTD PMID:21198554 NCBI chr 2:181,045,694...181,103,321
Ensembl chr 2:181,045,703...181,102,918
JBrowse link
G H1f2 H1.2 linker histone, cluster member decreases expression ISO Cytarabine results in decreased expression of H1-2 mRNA CTD PMID:21198554 NCBI chr17:43,638,938...43,640,445
Ensembl chr17:43,639,749...43,640,387
JBrowse link
G H2aj H2A.J histone decreases expression ISO Cytarabine results in decreased expression of H2AJ mRNA CTD PMID:21198554 NCBI chr 4:170,766,900...170,767,384
Ensembl chr 4:170,766,900...170,767,382
JBrowse link
G H2ax H2A.X variant histone increases phosphorylation ISO Cytarabine results in increased phosphorylation of H2AX protein CTD PMID:19628630 NCBI chr 8:48,665,652...48,666,981
Ensembl chr 8:48,665,652...48,666,981
JBrowse link
G Hand1 heart and neural crest derivatives expressed 1 decreases expression ISO Cytarabine results in decreased expression of HAND1 mRNA CTD PMID:21198554 NCBI chr10:43,250,729...43,253,296
Ensembl chr10:43,250,745...43,253,296
JBrowse link
G Hand2 heart and neural crest derivatives expressed 2 decreases expression ISO Cytarabine results in decreased expression of HAND2 mRNA CTD PMID:21198554 NCBI chr16:36,371,489...36,373,551
Ensembl chr16:36,371,489...36,373,546
JBrowse link
G Hapln1 hyaluronan and proteoglycan link protein 1 decreases expression ISO Cytarabine results in decreased expression of HAPLN1 mRNA CTD PMID:21198554 NCBI chr 2:18,354,542...18,419,077
Ensembl chr 2:18,354,542...18,419,071
JBrowse link
G Has2 hyaluronan synthase 2 decreases expression ISO Cytarabine results in decreased expression of HAS2 mRNA CTD PMID:21198554 NCBI chr 7:96,438,046...96,464,049
Ensembl chr 7:96,438,046...96,464,049
JBrowse link
G Hcfc1r1 host cell factor C1 regulator 1 decreases expression ISO Cytarabine results in decreased expression of HCFC1R1 mRNA CTD PMID:21198554 NCBI chr10:12,994,229...12,995,674
Ensembl chr10:12,994,683...12,995,457
JBrowse link
G Hes5 hes family bHLH transcription factor 5 increases expression ISO Cytarabine results in increased expression of HES5 mRNA CTD PMID:21198554 NCBI chr 5:172,364,421...172,365,188
Ensembl chr 5:172,364,421...172,365,188
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha increases expression ISO Cytarabine results in increased expression of HIF1A mRNA CTD PMID:23264188 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Hmgb1 high mobility group box 1 decreases response to substance
increases secretion
ISO HMGB1 protein results in decreased susceptibility to Cytarabine
Cytarabine results in increased secretion of HMGB1 protein
CTD PMID:27807322 NCBI chr12:7,082,529...7,090,246
Ensembl chr16:37,500,017...37,502,237
JBrowse link
G Hmgcs2 3-hydroxy-3-methylglutaryl-CoA synthase 2 decreases expression ISO Cytarabine results in decreased expression of HMGCS2 mRNA CTD PMID:21198554 NCBI chr 2:200,452,623...200,480,785
Ensembl chr 2:200,452,624...200,479,423
JBrowse link
G Hnrnpa3 heterogeneous nuclear ribonucleoprotein A3 decreases expression ISO Cytarabine results in decreased expression of HNRNPA3 mRNA CTD PMID:21198554 NCBI chr 3:62,481,222...62,491,356
Ensembl chr 3:62,481,323...62,487,227
JBrowse link
G Hoxa2 homeobox A2 increases expression ISO Cytarabine results in increased expression of HOXA2 mRNA CTD PMID:21198554 NCBI chr 4:82,130,441...82,134,846
Ensembl chr 4:82,131,329...82,133,605
JBrowse link
G Hoxa5 homeo box A5 increases expression ISO Cytarabine results in increased expression of HOXA5 mRNA CTD PMID:21198554
G Hoxb4 homeo box B4 decreases expression ISO Cytarabine results in decreased expression of HOXB4 mRNA CTD PMID:21198554 NCBI chr10:84,167,331...84,169,913
Ensembl chr10:84,167,331...84,169,907
JBrowse link
G Hoxb6 homeo box B6 decreases expression ISO Cytarabine results in decreased expression of HOXB6 mRNA CTD PMID:21198554 NCBI chr10:84,147,331...84,150,238
Ensembl chr10:84,147,836...84,149,600
JBrowse link
G Hoxb8 homeo box B8 decreases expression ISO Cytarabine results in decreased expression of HOXB8 mRNA CTD PMID:21198554 NCBI chr10:84,131,484...84,133,874
Ensembl chr10:84,131,495...84,133,246
JBrowse link
G Hoxc6 homeo box C6 decreases expression ISO Cytarabine results in decreased expression of HOXC6 mRNA CTD PMID:21198554 NCBI chr 7:144,612,230...144,626,036
Ensembl chr 7:144,623,555...144,625,516
JBrowse link
G Hoxc8 homeobox C8 decreases expression ISO Cytarabine results in decreased expression of HOXC8 mRNA CTD PMID:21198554 NCBI chr 7:144,605,072...144,607,639
Ensembl chr 7:144,605,058...144,608,538
JBrowse link
G Hs3st1 heparan sulfate-glucosamine 3-sulfotransferase 1 decreases expression ISO Cytarabine results in decreased expression of HS3ST1 mRNA CTD PMID:21198554 NCBI chr14:75,880,410...75,881,346
Ensembl chr14:75,852,060...75,882,693
JBrowse link
G Htra1 HtrA serine peptidase 1 decreases expression ISO Cytarabine results in decreased expression of HTRA1 mRNA CTD PMID:21198554 NCBI chr 1:201,499,067...201,548,508
Ensembl chr 1:201,499,028...201,548,513
JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 decreases expression ISO Cytarabine results in decreased expression of IGFBP3 mRNA CTD PMID:21198554 NCBI chr14:87,457,647...87,465,374
Ensembl chr14:87,457,647...87,465,374
JBrowse link
G Igfbp5 insulin-like growth factor binding protein 5 decreases expression ISO Cytarabine results in decreased expression of IGFBP5 mRNA CTD PMID:21198554 NCBI chr 9:80,154,230...80,166,813
Ensembl chr 9:80,150,211...80,167,033
JBrowse link
G Il6 interleukin 6 increases expression ISO Cytarabine results in increased expression of IL6 protein CTD PMID:11745875 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Ina internexin neuronal intermediate filament protein, alpha increases expression ISO Cytarabine results in increased expression of INA mRNA CTD PMID:21198554 NCBI chr 1:266,782,835...266,794,389
Ensembl chr 1:266,781,617...266,794,431
JBrowse link
G Irx5 iroquois homeobox 5 increases expression ISO Cytarabine results in increased expression of IRX5 mRNA CTD PMID:21198554 NCBI chr19:16,415,813...16,421,088
Ensembl chr19:16,415,636...16,421,191
JBrowse link
G Itgb5 integrin subunit beta 5 decreases expression ISO Cytarabine results in decreased expression of ITGB5 mRNA CTD PMID:21198554 NCBI chr11:70,056,500...70,172,164
Ensembl chr11:70,056,500...70,172,372
JBrowse link
G Itm2c integral membrane protein 2C decreases expression ISO Cytarabine results in decreased expression of ITM2C mRNA CTD PMID:21198554 NCBI chr 9:92,916,469...92,930,306
Ensembl chr 9:92,916,469...92,930,279
JBrowse link
G Jam2 junctional adhesion molecule 2 increases expression ISO Cytarabine results in increased expression of JAM2 mRNA CTD PMID:21198554 NCBI chr11:24,235,310...24,285,279
Ensembl chr11:24,266,345...24,285,275
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases expression ISO Cytarabine results in increased expression of JUN; Cytarabine results in increased expression of JUN mRNA CTD PMID:1450413, PMID:7949469 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Kank4 KN motif and ankyrin repeat domains 4 decreases expression ISO Cytarabine results in decreased expression of KANK4 mRNA CTD PMID:21198554 NCBI chr 5:117,376,425...117,440,643
Ensembl chr 5:117,376,423...117,440,254
JBrowse link
G Kcnn2 potassium calcium-activated channel subfamily N member 2 decreases expression ISO Cytarabine results in decreased expression of KCNN2 mRNA CTD PMID:21198554 NCBI chr18:39,331,894...39,479,574
Ensembl chr18:39,335,377...39,479,257
JBrowse link
G Kctd12 potassium channel tetramerization domain containing 12 decreases expression ISO Cytarabine results in decreased expression of KCTD12 mRNA CTD PMID:21198554 NCBI chr15:87,384,632...87,390,627 JBrowse link
G Kdelr3 KDEL endoplasmic reticulum protein retention receptor 3 decreases expression ISO Cytarabine results in decreased expression of KDELR3 mRNA CTD PMID:21198554 NCBI chr 7:120,749,680...120,760,163
Ensembl chr 7:120,749,752...120,760,160
JBrowse link
G Kif15 kinesin family member 15 increases expression ISO Cytarabine results in increased expression of KIF15 mRNA CTD PMID:21198554 NCBI chr 8:132,033,117...132,103,528
Ensembl chr 8:132,032,944...132,103,927
JBrowse link
G Klhl41 kelch-like family member 41 decreases expression ISO Cytarabine results in decreased expression of KLHL41 mRNA CTD PMID:21198554 NCBI chr 3:55,910,177...55,923,303
Ensembl chr 3:55,910,177...55,923,303
JBrowse link
G Klk6 kallikrein related-peptidase 6 decreases expression ISO Cytarabine results in decreased expression of KLK6 mRNA CTD PMID:21198554 NCBI chr 1:99,762,195...99,769,486
Ensembl chr 1:99,762,253...99,769,488
JBrowse link
G Kmo kynurenine 3-monooxygenase increases response to substance ISO KMO results in increased susceptibility to Cytarabine CTD PMID:21755009 NCBI chr13:93,684,324...93,715,378
Ensembl chr13:93,684,437...93,716,227
JBrowse link
G Kmt2a lysine methyltransferase 2A increases response to substance ISO KMT2A gene mutant form results in increased susceptibility to Cytarabine CTD PMID:14712291 NCBI chr 8:49,110,407...49,185,872
Ensembl chr 8:49,114,990...49,158,971
JBrowse link
G Kpna2 karyopherin subunit alpha 2 decreases expression ISO Cytarabine results in decreased expression of KPNA2 mRNA CTD PMID:17374387 NCBI chr10:95,200,029...95,212,111
Ensembl chr10:95,200,030...95,212,111
JBrowse link
G Krt19 keratin 19 decreases expression ISO Cytarabine results in decreased expression of KRT19 mRNA CTD PMID:21198554 NCBI chr10:88,055,843...88,060,560
Ensembl chr10:88,055,841...88,060,561
JBrowse link
G Krt24 keratin 24 decreases expression ISO Cytarabine results in decreased expression of KRT24 mRNA CTD PMID:21198554 NCBI chr10:87,190,184...87,195,075
Ensembl chr10:87,189,934...87,195,075
JBrowse link
G Krt8 keratin 8 decreases expression ISO Cytarabine results in decreased expression of KRT8 mRNA CTD PMID:21198554 NCBI chr 7:143,596,511...143,603,745
Ensembl chr 7:143,596,511...143,603,803
JBrowse link
G Kynu kynureninase decreases expression ISO Cytarabine results in decreased expression of KYNU mRNA CTD PMID:21198554 NCBI chr 3:28,416,926...28,566,939
Ensembl chr 3:28,416,954...28,566,928
JBrowse link
G Lbh LBH regulator of WNT signaling pathway decreases expression ISO Cytarabine results in decreased expression of LBH mRNA CTD PMID:21198554 NCBI chr 6:24,154,207...24,184,217
Ensembl chr 6:24,160,226...24,181,866
JBrowse link
G Lepr leptin receptor decreases expression ISO Cytarabine results in decreased expression of LEPR mRNA CTD PMID:21198554 NCBI chr 5:120,503,475...120,682,281
Ensembl chr 5:120,564,645...120,682,221
JBrowse link
G Lhfpl6 LHFPL tetraspan subfamily member 6 increases expression ISO Cytarabine results in increased expression of LHFPL6 mRNA CTD PMID:21198554 NCBI chr 2:142,262,236...142,461,980
Ensembl chr 2:142,262,236...142,461,980
JBrowse link
G Limch1 LIM and calponin homology domains 1 increases expression ISO Cytarabine results in increased expression of LIMCH1 mRNA CTD PMID:21198554 NCBI chr14:42,760,363...43,072,976
Ensembl chr14:42,762,587...43,072,843
JBrowse link
G Lmcd1 LIM and cysteine-rich domains 1 decreases expression ISO Cytarabine results in decreased expression of LMCD1 mRNA CTD PMID:21198554 NCBI chr 4:144,192,989...144,252,554
Ensembl chr 4:144,192,989...144,252,551
JBrowse link
G Lox lysyl oxidase decreases expression ISO Cytarabine results in decreased expression of LOX mRNA CTD PMID:21198554 NCBI chr18:47,500,320...47,577,819
Ensembl chr18:47,500,330...47,577,819
JBrowse link
G Loxl4 lysyl oxidase-like 4 decreases expression ISO Cytarabine results in decreased expression of LOXL4 mRNA CTD PMID:21198554 NCBI chr 1:261,833,365...261,853,599
Ensembl chr 1:261,835,992...261,853,495
JBrowse link
G Lrba LPS responsive beige-like anchor protein decreases expression ISO Cytarabine results in decreased expression of LRBA mRNA CTD PMID:21198554 NCBI chr 2:185,590,983...186,110,491
Ensembl chr 2:185,524,774...186,110,495
JBrowse link
G Lrfn5 leucine rich repeat and fibronectin type III domain containing 5 decreases expression ISO Cytarabine results in decreased expression of LRFN5 mRNA CTD PMID:21198554 NCBI chr 6:83,082,593...83,438,601
Ensembl chr 6:83,083,740...83,438,601
JBrowse link
G Lrig1 leucine-rich repeats and immunoglobulin-like domains 1 increases expression ISO Cytarabine results in increased expression of LRIG1 mRNA CTD PMID:21198554 NCBI chr 4:126,615,998...126,717,434
Ensembl chr 4:126,617,244...126,644,895
JBrowse link
G Lrrc32 leucine rich repeat containing 32 decreases expression ISO Cytarabine results in decreased expression of LRRC32 mRNA CTD PMID:21198554 NCBI chr 1:163,443,972...163,457,426
Ensembl chr 1:163,445,527...163,457,424
JBrowse link
G Lrrc41 leucine rich repeat containing 41 decreases expression ISO Cytarabine results in decreased expression of LRRC41 mRNA CTD PMID:21198554 NCBI chr 5:134,927,609...134,948,530
Ensembl chr 5:134,927,609...134,948,529
JBrowse link
G Lrrn2 leucine rich repeat neuronal 2 decreases expression ISO Cytarabine results in decreased expression of LRRN2 mRNA CTD PMID:21198554 NCBI chr13:49,660,356...49,730,275
Ensembl chr13:49,660,356...49,730,275
JBrowse link
G Lrrn3 leucine rich repeat neuronal 3 increases expression ISO Cytarabine results in increased expression of LRRN3 mRNA CTD PMID:21198554 NCBI chr 6:61,374,328...61,405,195
Ensembl chr 6:61,374,328...61,405,195
JBrowse link
G Lrrn4 leucine rich repeat neuronal 4 decreases expression ISO Cytarabine results in decreased expression of LRRN4 mRNA CTD PMID:21198554 NCBI chr 3:125,521,879...125,547,685
Ensembl chr 3:125,523,781...125,533,600
JBrowse link
G Lum lumican decreases expression ISO Cytarabine results in decreased expression of LUM mRNA CTD PMID:21198554 NCBI chr 7:38,820,058...38,826,862
Ensembl chr 7:38,819,771...38,826,862
JBrowse link
G Ly6h lymphocyte antigen 6 family member H decreases expression ISO Cytarabine results in decreased expression of LY6H mRNA CTD PMID:21198554 NCBI chr 7:116,605,556...116,608,072
Ensembl chr 7:116,605,558...116,607,674
JBrowse link
G Ly75 lymphocyte antigen 75 increases expression ISO Cytarabine results in increased expression of LY75 mRNA CTD PMID:19194470 NCBI chr 3:46,369,749...46,457,182
Ensembl chr 3:46,365,165...46,457,201
JBrowse link
G Lyl1 LYL1, basic helix-loop-helix family member decreases response to substance ISO LYL1 protein results in decreased susceptibility to Cytarabine CTD PMID:16094422 NCBI chr19:25,815,207...25,818,074
Ensembl chr19:25,815,207...25,818,074
JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase decreases expression ISO Cytarabine results in decreased expression of LYN mRNA CTD PMID:21198554 NCBI chr 5:16,526,058...16,642,648
Ensembl chr 5:16,526,058...16,642,648
JBrowse link
G Lyz2 lysozyme 2 increases expression ISO Cytarabine results in increased expression of LYZ mRNA CTD PMID:19194470 NCBI chr 7:60,335,968...60,341,264
Ensembl chr 7:60,335,969...60,341,264
JBrowse link
G Mab21l2 mab-21 like 2 decreases expression ISO Cytarabine results in decreased expression of MAB21L2 mRNA CTD PMID:21198554 NCBI chr 2:185,849,749...185,852,833
Ensembl chr 2:185,850,232...185,852,759
JBrowse link
G Magi1 membrane associated guanylate kinase, WW and PDZ domain containing 1 increases expression ISO Cytarabine results in increased expression of MAGI1 mRNA CTD PMID:21198554 NCBI chr 4:125,684,816...126,300,013
Ensembl chr 4:125,687,307...125,958,112
JBrowse link
G Map2 microtubule-associated protein 2 decreases expression
increases expression
ISO Cytarabine results in decreased expression of MAP2 protein
Cytarabine results in increased expression of MAP2 mRNA
CTD PMID:21198554 NCBI chr 9:73,204,753...73,462,965
Ensembl chr 9:73,319,710...73,462,972
JBrowse link
G Marchf3 membrane associated ring-CH-type finger 3 decreases expression ISO Cytarabine results in decreased expression of MARCHF3 mRNA CTD PMID:21198554 NCBI chr18:51,844,980...51,998,017
Ensembl chr18:51,844,976...52,017,734
JBrowse link
G Matn2 matrilin 2 decreases expression ISO Cytarabine results in decreased expression of MATN2 mRNA CTD PMID:21198554 NCBI chr 7:72,985,832...73,210,093
Ensembl chr 7:72,985,495...73,207,695
JBrowse link
G Mbtd1 mbt domain containing 1 increases expression ISO Cytarabine results in increased expression of MBTD1 mRNA CTD PMID:21198554 NCBI chr10:81,588,233...81,645,532
Ensembl chr10:81,592,114...81,642,663
JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member decreases expression ISO Cytarabine results in decreased expression of MCL1 protein CTD PMID:16818278 NCBI chr 2:197,786,212...197,788,992 JBrowse link
G Mcoln3 mucolipin 3 decreases expression ISO Cytarabine results in decreased expression of MCOLN3 mRNA CTD PMID:21198554 NCBI chr 2:251,930,532...252,007,722
Ensembl chr 2:251,983,339...252,007,560
JBrowse link
G Mdk midkine decreases expression ISO Cytarabine results in decreased expression of MDK mRNA CTD PMID:21198554 NCBI chr 3:80,841,003...80,843,895
Ensembl chr 3:80,841,005...80,842,916
JBrowse link
G Med9 mediator complex subunit 9 decreases expression ISO Cytarabine results in decreased expression of MED9 mRNA CTD PMID:19194470 NCBI chr10:46,314,639...46,329,374
Ensembl chr10:46,314,375...46,329,373
JBrowse link
G Megf10 multiple EGF-like domains 10 increases expression ISO Cytarabine results in increased expression of MEGF10 mRNA CTD PMID:21198554 NCBI chr18:52,215,652...52,366,212
Ensembl chr18:52,215,682...52,366,238
JBrowse link
G Meis1 Meis homeobox 1 increases expression ISO Cytarabine results in increased expression of MEIS1 mRNA CTD PMID:21198554 NCBI chr14:103,182,178...103,321,809
Ensembl chr14:103,181,281...103,321,270
JBrowse link
G Mertk MER proto-oncogene, tyrosine kinase decreases expression ISO Cytarabine results in decreased expression of MERTK mRNA CTD PMID:21198554 NCBI chr 3:121,235,230...121,340,932
Ensembl chr 3:121,235,119...121,342,444
JBrowse link
G Mfap4 microfibril associated protein 4 decreases expression ISO Cytarabine results in decreased expression of MFAP4 mRNA CTD PMID:21198554 NCBI chr10:47,765,463...47,768,484
Ensembl chr10:47,765,432...47,768,483
JBrowse link
G Mgarp mitochondria-localized glutamic acid-rich protein decreases expression ISO Cytarabine results in decreased expression of MGARP mRNA CTD PMID:21198554 NCBI chr 2:140,444,963...140,453,719
Ensembl chr 2:140,444,965...140,453,107
JBrowse link
G Mgp matrix Gla protein decreases expression ISO Cytarabine results in decreased expression of MGP mRNA CTD PMID:21198554 NCBI chr 4:170,856,783...170,860,105
Ensembl chr 4:170,856,751...170,860,225
JBrowse link
G Mindy4 MINDY lysine 48 deubiquitinase 4 decreases expression ISO Cytarabine results in decreased expression of MINDY4 mRNA CTD PMID:21198554 NCBI chr 4:85,427,741...85,536,264
Ensembl chr 4:85,427,555...85,532,238
JBrowse link
G Mmp23 matrix metallopeptidase 23 decreases expression ISO Cytarabine results in decreased expression of MMP23B mRNA CTD PMID:21198554 NCBI chr 5:173,078,811...173,082,834
Ensembl chr 5:173,078,590...173,081,839
JBrowse link
G Mpp6 membrane palmitoylated protein 6 decreases expression ISO Cytarabine results in decreased expression of MPP6 mRNA CTD PMID:21198554 NCBI chr 4:79,846,506...79,928,977
Ensembl chr 4:79,846,521...79,926,703
JBrowse link
G Mpzl1 myelin protein zero-like 1 decreases expression ISO Cytarabine results in decreased expression of MPZL1 mRNA CTD PMID:21198554 NCBI chr13:83,805,244...83,842,074
Ensembl chr13:83,805,244...83,842,051
JBrowse link
G Msx1 msh homeobox 1 decreases expression ISO Cytarabine results in decreased expression of MSX1 mRNA CTD PMID:21198554 NCBI chr14:77,712,262...77,716,061
Ensembl chr14:77,712,240...77,716,059
JBrowse link
G Mt1 metallothionein 1 decreases expression ISO Cytarabine results in decreased expression of MT1A mRNA CTD PMID:21198554 NCBI chr19:11,301,991...11,303,007
Ensembl chr17:78,793,336...78,793,724
JBrowse link
G Mt2A metallothionein 2A decreases expression ISO Cytarabine results in decreased expression of MT2A mRNA CTD PMID:21198554 NCBI chr19:11,307,966...11,308,740
Ensembl chr19:11,307,967...11,308,740
JBrowse link
G Mthfr methylenetetrahydrofolate reductase affects response to substance ISO MTHFR protein affects the susceptibility to Cytarabine CTD PMID:18202788 NCBI chr 5:164,844,642...164,864,360
Ensembl chr 5:164,845,925...164,860,910
JBrowse link
G Mtus1 microtubule associated scaffold protein 1 increases expression ISO Cytarabine results in increased expression of MTUS1 mRNA CTD PMID:21198554 NCBI chr16:54,240,892...54,386,131
Ensembl chr16:54,291,251...54,386,129
JBrowse link
G Mvb12a multivesicular body subunit 12A decreases expression ISO Cytarabine results in decreased expression of MVB12A mRNA CTD PMID:21198554 NCBI chr16:19,973,611...19,978,479
Ensembl chr16:19,973,636...19,978,478
JBrowse link
G Mxd3 Max dimerization protein 3 increases expression ISO Cytarabine results in increased expression of MXD3 mRNA CTD PMID:21198554 NCBI chr17:9,830,326...9,834,052
Ensembl chr17:9,830,332...9,839,452
JBrowse link
G Mxra7 matrix remodeling associated 7 decreases expression ISO Cytarabine results in decreased expression of MXRA7 mRNA CTD PMID:21198554 NCBI chr10:105,743,669...105,772,038
Ensembl chr10:105,745,276...105,771,972
JBrowse link
G Myadm myeloid-associated differentiation marker decreases expression ISO Cytarabine results in decreased expression of MYADM mRNA CTD PMID:21198554 NCBI chr 1:64,438,465...64,448,332
Ensembl chr 1:64,438,472...64,446,818
JBrowse link
G Mydgf myeloid-derived growth factor decreases expression ISO Cytarabine results in decreased expression of MYDGF mRNA CTD PMID:21198554 NCBI chr 9:10,885,521...10,892,744
Ensembl chr 9:10,885,560...10,892,405
JBrowse link
G Myl4 myosin, light chain 4 decreases expression ISO Cytarabine results in decreased expression of MYL4 mRNA CTD PMID:21198554 NCBI chr10:92,628,356...92,638,100
Ensembl chr10:92,628,356...92,638,100
JBrowse link
G Myl7 myosin light chain 7 decreases expression ISO Cytarabine results in decreased expression of MYL7 mRNA CTD PMID:21198554 NCBI chr14:86,144,770...86,147,075
Ensembl chr14:86,143,862...86,147,553
JBrowse link
G Mylip myosin regulatory light chain interacting protein decreases expression ISO Cytarabine results in decreased expression of MYLIP mRNA CTD PMID:21198554 NCBI chr17:19,682,040...19,703,681
Ensembl chr17:19,682,040...19,703,681
JBrowse link
G Myof myoferlin decreases expression ISO Cytarabine results in decreased expression of MYOF mRNA CTD PMID:21198554 NCBI chr 1:256,585,410...256,734,727
Ensembl chr 1:256,585,410...256,734,730
JBrowse link
G Nav2 neuron navigator 2 decreases expression ISO Cytarabine results in decreased expression of NAV2 mRNA CTD PMID:21198554 NCBI chr 1:104,575,765...104,941,554
Ensembl chr 1:104,576,589...104,941,552
JBrowse link
G Ncald neurocalcin delta increases expression ISO Cytarabine results in increased expression of NCALD mRNA CTD PMID:21198554 NCBI chr 7:76,199,305...76,632,847
Ensembl chr 7:76,199,306...76,488,216
JBrowse link
G Ndc80 NDC80 kinetochore complex component increases expression ISO Cytarabine results in increased expression of NDC80 mRNA CTD PMID:19194470 NCBI chr 9:119,837,857...119,871,435
Ensembl chr 9:119,839,016...119,871,382
JBrowse link
G Ndrg1 N-myc downstream regulated 1 decreases expression ISO Cytarabine results in decreased expression of NDRG1 mRNA CTD PMID:21198554 NCBI chr 7:107,734,326...107,775,701
Ensembl chr 7:107,734,323...107,775,714
JBrowse link
G Ndrg2 NDRG family member 2 decreases expression ISO Cytarabine results in decreased expression of NDRG2 mRNA CTD PMID:21198554 NCBI chr15:28,305,820...28,314,459
Ensembl chr15:28,305,821...28,314,459
JBrowse link
G Nell2 neural EGFL like 2 increases expression ISO Cytarabine results in increased expression of NELL2 mRNA CTD PMID:21198554 NCBI chr 7:136,526,497...136,853,820
Ensembl chr 7:136,526,496...136,853,957
JBrowse link
G Nes nestin increases expression
decreases expression
ISO Cytarabine results in increased expression of NES mRNA
Cytarabine results in decreased expression of NES protein
CTD PMID:21198554 NCBI chr 2:187,343,109...187,352,972
Ensembl chr 2:187,344,056...187,352,969
JBrowse link
G Nfib nuclear factor I/B increases expression ISO Cytarabine results in increased expression of NFIB mRNA CTD PMID:21198554 NCBI chr 5:100,436,343...100,647,962
Ensembl chr 5:100,439,082...100,647,727
JBrowse link
G Niban2 niban apoptosis regulator 2 decreases expression ISO Cytarabine results in decreased expression of NIBAN2 mRNA CTD PMID:21198554 NCBI chr 3:11,921,715...11,971,327
Ensembl chr 3:11,921,715...11,971,327
JBrowse link
G Nmu neuromedin U increases expression ISO Cytarabine results in increased expression of NMU mRNA CTD PMID:21198554 NCBI chr14:34,353,683...34,381,968
Ensembl chr14:34,354,503...34,381,828
JBrowse link
G Nova1 NOVA alternative splicing regulator 1 increases expression ISO Cytarabine results in increased expression of NOVA1 mRNA CTD PMID:21198554 NCBI chr 6:66,960,126...67,085,836
Ensembl chr 6:66,963,510...67,085,390
JBrowse link
G Nox4 NADPH oxidase 4 decreases expression ISO Cytarabine results in decreased expression of NOX4 mRNA CTD PMID:21198554 NCBI chr 1:150,796,359...150,976,186
Ensembl chr 1:150,797,084...150,976,194
JBrowse link
G Nppb natriuretic peptide B increases expression ISO Cytarabine results in increased expression of NPPB mRNA; Cytarabine results in increased expression of NPPB protein CTD PMID:16151589, PMID:21198554 NCBI chr 5:164,796,176...164,797,538
Ensembl chr 5:164,796,185...164,797,531
JBrowse link
G Npy neuropeptide Y decreases expression ISO Cytarabine results in decreased expression of NPY mRNA CTD PMID:21198554 NCBI chr 4:79,557,856...79,565,059
Ensembl chr 4:79,557,854...79,565,097
JBrowse link
G Nrip3 nuclear receptor interacting protein 3 decreases expression ISO Cytarabine results in decreased expression of NRIP3 mRNA CTD PMID:21198554 NCBI chr 1:174,385,424...174,411,141
Ensembl chr 1:174,385,424...174,411,141
JBrowse link
G Nrp1 neuropilin 1 multiple interactions ISO [2,2-bis(4-glycidyloxyphenyl)propane co-treated with Cytarabine] results in decreased expression of NRP1 mRNA CTD PMID:23264188 NCBI chr19:61,332,351...61,486,166
Ensembl chr19:61,332,351...61,485,858
JBrowse link
G Ntm neurotrimin decreases expression ISO Cytarabine results in decreased expression of NTM mRNA CTD PMID:21198554 NCBI chr 8:30,039,332...31,041,755
Ensembl chr 8:30,039,408...30,222,036
JBrowse link
G Ntng1 netrin G1 increases expression ISO Cytarabine results in increased expression of NTNG1 mRNA CTD PMID:21198554 NCBI chr 2:212,695,464...213,073,046
Ensembl chr 2:212,696,624...212,852,870
JBrowse link
G Odam odontogenic, ameloblast associated decreases expression ISO Cytarabine results in decreased expression of ODAM mRNA CTD PMID:21198554 NCBI chr14:21,842,990...21,852,216
Ensembl chr14:21,842,990...21,852,216
JBrowse link
G Olfml3 olfactomedin-like 3 decreases expression ISO Cytarabine results in decreased expression of OLFML3 mRNA CTD PMID:21198554 NCBI chr 2:206,219,419...206,222,248
Ensembl chr 2:206,219,419...206,222,248
JBrowse link
G Olr1 oxidized low density lipoprotein receptor 1 decreases expression ISO Cytarabine results in decreased expression of OLR1 mRNA CTD PMID:21198554 NCBI chr 4:163,239,853...163,261,937
Ensembl chr 4:163,239,849...163,261,958
JBrowse link
G Osbpl10 oxysterol binding protein-like 10 decreases expression ISO Cytarabine results in decreased expression of OSBPL10 mRNA CTD PMID:21198554 NCBI chr 8:123,029,722...123,303,553
Ensembl chr 8:123,126,667...123,293,562
JBrowse link
G Osr1 odd-skipped related transcription factor 1 decreases expression ISO Cytarabine results in decreased expression of OSR1 mRNA CTD PMID:21198554 NCBI chr 6:35,314,431...35,321,458
Ensembl chr 6:35,314,444...35,321,667
JBrowse link
G P4ha2 prolyl 4-hydroxylase subunit alpha 2 decreases expression ISO Cytarabine results in decreased expression of P4HA2 mRNA CTD PMID:21198554 NCBI chr10:39,435,227...39,464,134
Ensembl chr10:39,435,227...39,464,188
JBrowse link
G Pamr1 peptidase domain containing associated with muscle regeneration 1 decreases expression ISO Cytarabine results in decreased expression of PAMR1 mRNA CTD PMID:21198554 NCBI chr 3:92,403,533...92,502,094
Ensembl chr 3:92,403,582...92,502,089
JBrowse link
G Pard6a par-6 family cell polarity regulator alpha decreases expression ISO Cytarabine results in decreased expression of PARD6A mRNA CTD PMID:19194470 NCBI chr19:37,668,133...37,670,450
Ensembl chr19:37,668,133...37,672,729
JBrowse link
G Parm1 prostate androgen-regulated mucin-like protein 1 decreases expression ISO Cytarabine results in decreased expression of PARM1 mRNA CTD PMID:21198554 NCBI chr14:17,972,914...18,076,870
Ensembl chr14:17,969,219...18,076,907
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions
increases degradation
ISO [Cytarabine co-treated with TNFSF10 protein] results in increased cleavage of PARP1 protein; BCL2 protein inhibits the reaction [Cytarabine results in increased degradation of PARP1 protein]; BCL2L1 protein inhibits the reaction [Cytarabine results in increased degradation of PARP1 protein] CTD PMID:8840993, PMID:12780785 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Pax6 paired box 6 increases expression
decreases expression
ISO Cytarabine results in increased expression of PAX6 mRNA
Cytarabine results in decreased expression of PAX6 protein
CTD PMID:21198554 NCBI chr 3:95,700,241...95,728,682
Ensembl chr 3:95,707,386...95,728,624
JBrowse link
G Pcdh20 protocadherin 20 decreases expression ISO Cytarabine results in decreased expression of PCDH20 mRNA CTD PMID:21198554 NCBI chr15:71,772,777...71,779,033
Ensembl chr15:71,772,777...71,779,033
JBrowse link
G Pcdh7 protocadherin 7 decreases expression ISO Cytarabine results in decreased expression of PCDH7 mRNA CTD PMID:21198554 NCBI chr14:54,649,054...55,081,632
Ensembl chr14:55,072,200...55,081,551
JBrowse link
G Pced1b PC-esterase domain containing 1B decreases expression ISO Cytarabine results in decreased expression of PCED1B mRNA CTD PMID:21198554 NCBI chr 7:138,707,426...138,846,127
Ensembl chr 7:138,707,426...138,846,123
JBrowse link
G Pcsk5 proprotein convertase subtilisin/kexin type 5 decreases expression ISO Cytarabine results in decreased expression of PCSK5 mRNA CTD PMID:21198554 NCBI chr 1:236,031,988...236,313,858
Ensembl chr 1:236,031,988...236,313,858
JBrowse link
G Pde1a phosphodiesterase 1A increases expression ISO Cytarabine results in increased expression of PDE1A mRNA CTD PMID:21198554 NCBI chr 3:66,803,247...67,263,658
Ensembl chr 3:66,803,247...66,885,094
JBrowse link
G Pde1b phosphodiesterase 1B increases expression ISO Cytarabine results in increased expression of PDE1B mRNA CTD PMID:21198554 NCBI chr 7:145,117,951...145,147,711
Ensembl chr 7:145,117,951...145,145,376
JBrowse link
G Pde4b phosphodiesterase 4B increases expression ISO Cytarabine results in increased expression of PDE4B mRNA CTD PMID:21198554 NCBI chr 5:121,759,236...122,136,814
Ensembl chr 5:121,952,977...122,136,814
JBrowse link
G Pde6d phosphodiesterase 6D decreases expression ISO Cytarabine results in decreased expression of PDE6D mRNA CTD PMID:19194470 NCBI chr 9:93,562,099...93,607,061
Ensembl chr 9:93,562,095...93,607,087
JBrowse link
G Pdgfrb platelet derived growth factor receptor beta decreases expression ISO Cytarabine results in decreased expression of PDGFRB mRNA CTD PMID:21198554 NCBI chr18:56,364,586...56,406,381
Ensembl chr18:56,364,620...56,406,381
JBrowse link
G Pdlim3 PDZ and LIM domain 3 increases expression ISO Cytarabine results in increased expression of PDLIM3 mRNA CTD PMID:21198554 NCBI chr16:49,543,140...49,574,362
Ensembl chr16:49,543,142...49,574,390
JBrowse link
G Pdlim4 PDZ and LIM domain 4 multiple interactions ISO Cytarabine inhibits the reaction [decitabine results in increased expression of PDLIM4 mRNA] CTD PMID:17634552 NCBI chr10:39,390,578...39,405,322
Ensembl chr10:39,390,581...39,405,311
JBrowse link
G Pdpn podoplanin decreases expression ISO Cytarabine results in decreased expression of PDPN mRNA CTD PMID:21198554 NCBI chr 5:161,947,137...161,981,441
Ensembl chr 5:161,947,137...161,981,441
JBrowse link
G Peli1 pellino E3 ubiquitin protein ligase 1 increases expression ISO Cytarabine results in increased expression of PELI1 mRNA CTD PMID:21198554 NCBI chr14:106,008,086...106,062,566
Ensembl chr14:106,008,086...106,061,641
JBrowse link
G Pfkp phosphofructokinase, platelet decreases expression ISO Cytarabine results in decreased expression of PFKP mRNA CTD PMID:21198554 NCBI chr17:68,510,765...68,574,387
Ensembl chr17:68,511,064...68,559,471
JBrowse link
G Pgm5 phosphoglucomutase 5 decreases expression ISO Cytarabine results in decreased expression of PGM5 mRNA CTD PMID:21198554 NCBI chr 1:242,582,591...242,765,837
Ensembl chr 1:242,582,642...242,765,807
JBrowse link
G Phactr2 phosphatase and actin regulator 2 decreases expression ISO Cytarabine results in decreased expression of PHACTR2 mRNA CTD PMID:21198554 NCBI chr 1:7,352,050...7,633,991
Ensembl chr 1:7,355,154...7,480,825
JBrowse link
G Phyhipl phytanoyl-CoA 2-hydroxylase interacting protein-like increases expression ISO Cytarabine results in increased expression of PHYHIPL mRNA CTD PMID:21198554 NCBI chr20:19,318,090...19,359,063
Ensembl chr20:19,318,250...19,358,719
JBrowse link
G Pigh phosphatidylinositol glycan anchor biosynthesis, class H decreases expression ISO Cytarabine results in decreased expression of PIGH mRNA CTD PMID:21198554 NCBI chr 6:102,258,621...102,272,826
Ensembl chr 6:102,263,337...102,272,777
JBrowse link
G Pitx1 paired-like homeodomain 1 decreases expression ISO Cytarabine results in decreased expression of PITX1 mRNA CTD PMID:21198554 NCBI chr17:8,873,184...8,884,428
Ensembl chr17:8,878,270...8,884,423
JBrowse link
G Pitx2 paired-like homeodomain 2 decreases expression ISO Cytarabine results in decreased expression of PITX2 mRNA CTD PMID:21198554 NCBI chr 2:233,602,732...233,621,059
Ensembl chr 2:233,602,732...233,621,129
JBrowse link
G Pkia cAMP-dependent protein kinase inhibitor alpha decreases expression ISO Cytarabine results in decreased expression of PKIA mRNA CTD PMID:21198554 NCBI chr 2:96,593,185...96,668,222
Ensembl chr 2:96,595,088...96,668,222
JBrowse link
G Pkp2 plakophilin 2 decreases expression ISO Cytarabine results in decreased expression of PKP2 mRNA CTD PMID:21198554 NCBI chr11:88,912,163...88,972,213 JBrowse link
G Plac9 placenta associated 9 decreases expression ISO Cytarabine results in decreased expression of PLAC9 mRNA CTD PMID:21198554 NCBI chr16:3,851,107...3,866,008
Ensembl chr16:3,851,270...3,866,008
JBrowse link
G Plat plasminogen activator, tissue type decreases expression ISO Cytarabine results in decreased expression of PLAT mRNA CTD PMID:21198554 NCBI chr16:74,098,263...74,122,897
Ensembl chr16:74,098,260...74,122,889
JBrowse link
G Plcb2 phospholipase C, beta 2 affects localization
multiple interactions
ISO Cytarabine affects the localization of PLCB2 protein
edelfosine inhibits the reaction [Cytarabine affects the localization of PLCB2 protein]
CTD PMID:9295281 NCBI chr 3:110,497,760...110,517,563
Ensembl chr 3:110,498,114...110,517,163
JBrowse link
G Plch1 phospholipase C, eta 1 increases expression ISO Cytarabine results in increased expression of PLCH1 mRNA CTD PMID:21198554 NCBI chr 2:154,256,382...154,468,166
Ensembl chr 2:154,256,380...154,418,920
JBrowse link
G Pld3 phospholipase D family, member 3 decreases expression ISO Cytarabine results in decreased expression of PLD3 mRNA CTD PMID:21198554 NCBI chr 1:84,339,269...84,361,686
Ensembl chr 1:84,339,261...84,353,725
JBrowse link
G Plekhg3 pleckstrin homology and RhoGEF domain containing G3 decreases expression ISO Cytarabine results in decreased expression of PLEKHG3 mRNA CTD PMID:21198554 NCBI chr 6:99,612,993...99,655,753
Ensembl chr 6:99,625,306...99,655,362
JBrowse link
G Plg plasminogen affects localization ISO Cytarabine affects the localization of PLG protein CTD PMID:12165291 NCBI chr 1:48,521,828...48,563,895
Ensembl chr 1:48,521,772...48,563,776
JBrowse link
G Plin3 perilipin 3 decreases expression ISO Cytarabine results in decreased expression of PLIN3 mRNA CTD PMID:21198554 NCBI chr 9:10,769,739...10,781,659
Ensembl chr 9:10,773,901...10,781,109
JBrowse link
G Pllp plasmolipin decreases expression ISO Cytarabine results in decreased expression of PLLP mRNA CTD PMID:21198554 NCBI chr19:10,731,855...10,752,641
Ensembl chr19:10,731,855...10,752,641
JBrowse link
G Plod1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 decreases expression ISO Cytarabine results in decreased expression of PLOD1 mRNA CTD PMID:21198554 NCBI chr 5:164,720,629...164,747,071
Ensembl chr 5:164,720,587...164,747,083
JBrowse link
G Plp1 proteolipid protein 1 increases expression ISO Cytarabine results in increased expression of PLP1 mRNA CTD PMID:21198554 NCBI chr  X:107,494,326...107,511,355
Ensembl chr  X:107,496,072...107,511,348
JBrowse link
G Pltp phospholipid transfer protein decreases expression ISO Cytarabine results in decreased expression of PLTP mRNA CTD PMID:21198554 NCBI chr 3:161,304,469...161,322,289
Ensembl chr 3:161,304,469...161,322,289
JBrowse link
G Pmel premelanosome protein increases expression ISO Cytarabine results in increased expression of PMEL mRNA CTD PMID:21198554 NCBI chr 7:3,133,347...3,143,827
Ensembl chr 7:3,133,506...3,143,911
JBrowse link
G Pmp22 peripheral myelin protein 22 decreases expression ISO Cytarabine results in decreased expression of PMP22 mRNA CTD PMID:21198554 NCBI chr10:49,538,588...49,568,583
Ensembl chr10:49,538,588...49,568,583
JBrowse link
G Podxl podocalyxin-like decreases expression ISO Cytarabine results in decreased expression of PODXL mRNA CTD PMID:21198554 NCBI chr 4:58,829,049...58,893,353
Ensembl chr 4:58,829,060...58,893,170
JBrowse link
G Podxl2 podocalyxin-like 2 increases expression ISO Cytarabine results in increased expression of PODXL2 mRNA CTD PMID:21198554 NCBI chr 4:120,785,494...120,817,335
Ensembl chr 4:120,785,495...120,817,377
JBrowse link
G Postn periostin decreases expression ISO Cytarabine results in decreased expression of POSTN mRNA CTD PMID:21198554 NCBI chr 2:143,656,820...143,688,087
Ensembl chr 2:143,656,793...143,688,087
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions
increases expression
ISO 2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [Cytarabine results in increased expression of PPARG mRNA] CTD PMID:23264188 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Ppic peptidylprolyl isomerase C decreases expression ISO Cytarabine results in decreased expression of PPIC mRNA CTD PMID:21198554 NCBI chr18:48,372,039...48,384,645
Ensembl chr18:48,372,041...48,384,645
JBrowse link
G Ppm1m protein phosphatase, Mg2+/Mn2+ dependent, 1M decreases expression ISO Cytarabine results in decreased expression of PPM1M mRNA CTD PMID:21198554 NCBI chr 8:114,887,894...114,893,773
Ensembl chr 8:114,888,746...114,892,910
JBrowse link
G Ppt2 palmitoyl-protein thioesterase 2 decreases expression ISO Cytarabine results in decreased expression of PPT2 mRNA CTD PMID:21198554 NCBI chr20:4,381,455...4,401,638
Ensembl chr20:4,381,455...4,401,610
JBrowse link
G Prc1 protein regulator of cytokinesis 1 decreases expression ISO Cytarabine results in decreased expression of PRC1 mRNA CTD PMID:17374387 NCBI chr 1:142,087,181...142,108,746
Ensembl chr 1:142,087,208...142,108,746
JBrowse link
G Prdm8 PR/SET domain 8 increases expression ISO Cytarabine results in increased expression of PRDM8 mRNA CTD PMID:21198554 NCBI chr14:13,052,776...13,073,583
Ensembl chr14:13,054,771...13,058,172
JBrowse link
G Prickle1 prickle planar cell polarity protein 1 decreases expression ISO Cytarabine results in decreased expression of PRICKLE1 mRNA CTD PMID:21198554 NCBI chr 7:134,702,964...134,799,437
Ensembl chr 7:134,702,964...134,722,215
JBrowse link
G Prkcz protein kinase C, zeta decreases response to substance ISO PRKCZ protein results in decreased susceptibility to Cytarabine CTD PMID:21863889 NCBI chr 5:172,658,071...172,769,492
Ensembl chr 5:172,658,748...172,769,421
JBrowse link
G Prl prolactin increases expression ISO Cytarabine results in increased expression of PRL protein CTD PMID:8312290 NCBI chr17:39,814,236...39,824,299
Ensembl chr17:39,814,244...39,824,299
JBrowse link
G Prnp prion protein decreases expression ISO Cytarabine results in decreased expression of PRNP mRNA CTD PMID:21198554 NCBI chr 3:124,515,917...124,531,320
Ensembl chr 3:124,515,978...124,531,316
JBrowse link
G Prph peripherin decreases expression ISO Cytarabine results in decreased expression of PRPH mRNA CTD PMID:21198554 NCBI chr 7:140,742,406...140,746,197
Ensembl chr 7:140,742,418...140,746,197
JBrowse link
G Prrc2c proline-rich coiled-coil 2C decreases expression ISO Cytarabine results in decreased expression of PRRC2C mRNA CTD PMID:19194470 NCBI chr13:80,544,789...80,614,925 JBrowse link
G Prss35 serine protease 35 decreases expression ISO Cytarabine results in decreased expression of PRSS35 mRNA CTD PMID:21198554 NCBI chr 8:94,423,629...94,440,509
Ensembl chr 8:94,423,808...94,440,503
JBrowse link
G Psd3 pleckstrin and Sec7 domain containing 3 increases expression ISO Cytarabine results in increased expression of PSD3 mRNA CTD PMID:21198554 NCBI chr16:23,212,165...23,789,414
Ensembl chr16:23,447,366...23,781,604
JBrowse link
G Psrc1 proline and serine rich coiled-coil 1 decreases expression ISO Cytarabine results in decreased expression of PSRC1 mRNA CTD PMID:17374387 NCBI chr 2:211,176,437...211,181,078
Ensembl chr 2:211,176,556...211,181,123
JBrowse link
G Pstpip2 proline-serine-threonine phosphatase-interacting protein 2 decreases expression ISO Cytarabine results in decreased expression of PSTPIP2 mRNA CTD PMID:19194470 NCBI chr18:74,173,809...74,291,188
Ensembl chr18:74,174,936...74,292,921
JBrowse link
G Pten phosphatase and tensin homolog increases response to substance ISO PTEN protein results in increased susceptibility to Cytarabine CTD PMID:22185283 NCBI chr 1:251,421,814...251,487,634
Ensembl chr 1:251,421,596...251,487,832
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO PTGS2 mutant form affects the reaction [VEGFC protein results in decreased susceptibility to Cytarabine]
PTGS2 mutant form inhibits the reaction [VEGFC protein results in decreased susceptibility to Cytarabine]
CTD PMID:24184161 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Pth1r parathyroid hormone 1 receptor decreases expression ISO Cytarabine results in decreased expression of PTH1R mRNA CTD PMID:21198554 NCBI chr 8:118,984,531...119,012,803
Ensembl chr 8:118,988,053...119,012,671
JBrowse link
G Ptprz1 protein tyrosine phosphatase, receptor type Z1 increases expression ISO Cytarabine results in increased expression of PTPRZ1 mRNA CTD PMID:21198554 NCBI chr 4:49,941,046...50,140,764
Ensembl chr 4:49,941,304...50,140,762
JBrowse link
G Qprt quinolinate phosphoribosyltransferase decreases expression ISO Cytarabine results in decreased expression of QPRT mRNA CTD PMID:21198554 NCBI chr 1:198,544,262...198,559,556
Ensembl chr 1:198,544,262...198,559,568
JBrowse link
G Rab37 RAB37, member RAS oncogene family decreases expression ISO Cytarabine results in decreased expression of RAB37 mRNA CTD PMID:21198554 NCBI chr10:103,643,841...103,711,830
Ensembl chr10:103,703,404...103,710,527
JBrowse link
G Rab5b RAB5B, member RAS oncogene family increases expression ISO Cytarabine results in increased expression of RAB5B mRNA CTD PMID:19194470 NCBI chr 7:3,104,530...3,123,384
Ensembl chr 7:3,104,551...3,123,297
JBrowse link
G Rabggtb Rab geranylgeranyltransferase subunit beta decreases expression ISO Cytarabine results in decreased expression of RABGGTB mRNA CTD PMID:19194470 NCBI chr 2:260,110,309...260,115,574
Ensembl chr 2:260,110,309...260,115,577
JBrowse link
G Rad23a RAD23 homolog A, nucleotide excision repair protein decreases expression ISO Cytarabine results in decreased expression of RAD23A mRNA CTD PMID:19194470 NCBI chr19:25,949,488...25,956,677
Ensembl chr19:25,949,490...25,955,391
JBrowse link
G Rad51 RAD51 recombinase increases expression ISO Cytarabine results in increased expression of RAD51 mRNA CTD PMID:19194470 NCBI chr 3:110,918,240...110,942,920
Ensembl chr 3:110,918,243...110,942,917
JBrowse link
G Ramp1 receptor activity modifying protein 1 decreases expression ISO Cytarabine results in decreased expression of RAMP1 mRNA CTD PMID:21198554 NCBI chr 9:98,313,632...98,364,206
Ensembl chr 9:98,313,632...98,364,205
JBrowse link
G Rassf2 Ras association domain family member 2 increases expression ISO Cytarabine results in increased expression of RASSF2 mRNA CTD PMID:21198554 NCBI chr 3:124,574,088...124,610,267
Ensembl chr 3:124,575,621...124,610,267
JBrowse link
G Rbm34 RNA binding motif protein 34 decreases expression ISO Cytarabine results in decreased expression of RBM34 mRNA CTD PMID:19194470 NCBI chr19:59,874,745...59,894,981
Ensembl chr19:59,874,752...59,894,937
JBrowse link
G Recql5 RecQ like helicase 5 decreases expression ISO Cytarabine results in decreased expression of RECQL5 mRNA CTD PMID:19194470 NCBI chr10:104,443,735...104,482,889
Ensembl chr10:104,443,736...104,482,838
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions
decreases phosphorylation
decreases activity
ISO calyculin A inhibits the reaction [Cytarabine results in decreased activity of RELA protein]
Cytarabine results in decreased phosphorylation of RELA protein
CTD PMID:12853972 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Reln reelin decreases expression ISO Cytarabine results in decreased expression of RELN mRNA CTD PMID:21198554 NCBI chr 4:9,347,533...9,774,257
Ensembl chr 4:9,347,528...9,773,670
JBrowse link
G Rerg RAS-like, estrogen-regulated, growth-inhibitor decreases expression ISO Cytarabine results in decreased expression of RERG mRNA CTD PMID:21198554 NCBI chr 4:171,069,161...171,176,678
Ensembl chr 4:171,069,191...171,176,581
JBrowse link
G Rexo4 REX4 homolog, 3'-5' exonuclease decreases expression ISO Cytarabine results in decreased expression of REXO4 mRNA CTD PMID:21198554 NCBI chr 3:5,500,578...5,510,908
Ensembl chr 3:5,500,589...5,510,908
JBrowse link
G RGD1306556 similar to hypothetical protein A530094D01 decreases expression ISO Cytarabine results in decreased expression of KIAA1671 mRNA CTD PMID:21198554 NCBI chr12:49,418,026...49,561,038
Ensembl chr12:49,419,582...49,561,038
JBrowse link
G Rgl1 ral guanine nucleotide dissociation stimulator,-like 1 decreases expression ISO Cytarabine results in decreased expression of RGL1 mRNA CTD PMID:21198554 NCBI chr13:69,909,122...70,174,590
Ensembl chr13:69,909,096...70,174,565
JBrowse link
G Rgmb repulsive guidance molecule BMP co-receptor b increases expression ISO Cytarabine results in increased expression of RGMB mRNA CTD PMID:21198554 NCBI chr 1:57,794,046...57,819,941
Ensembl chr 1:57,796,709...57,815,038
JBrowse link
G Rgs1 regulator of G-protein signaling 1 decreases expression ISO Cytarabine results in decreased expression of RGS1 mRNA CTD PMID:21198554 NCBI chr13:61,066,196...61,070,772
Ensembl chr13:61,066,153...61,070,599
JBrowse link
G Rgs13 regulator of G-protein signaling 13 decreases expression ISO Cytarabine results in decreased expression of RGS13 mRNA CTD PMID:21198554 NCBI chr13:60,970,172...61,004,260
Ensembl chr13:60,970,247...61,003,744
JBrowse link
G Rgs20 regulator of G-protein signaling 20 increases expression ISO Cytarabine results in increased expression of RGS20 mRNA CTD PMID:21198554 NCBI chr 5:14,367,498...14,494,048
Ensembl chr 5:14,415,606...14,494,756
JBrowse link
G Rgs4 regulator of G-protein signaling 4 decreases expression ISO Cytarabine results in decreased expression of RGS4 mRNA CTD PMID:21198554 NCBI chr13:88,054,817...88,061,108
Ensembl chr13:88,054,817...88,061,108
JBrowse link
G Rhoc ras homolog family member C decreases expression ISO Cytarabine results in decreased expression of RHOC mRNA CTD PMID:21198554 NCBI chr 2:207,271,692...207,278,010
Ensembl chr 2:207,271,853...207,279,314
JBrowse link
G Rhpn2 rhophilin, Rho GTPase binding protein 2 decreases expression ISO Cytarabine results in decreased expression of RHPN2 mRNA CTD PMID:21198554 NCBI chr 1:91,596,344...91,657,395
Ensembl chr 1:91,596,397...91,657,395
JBrowse link
G Rnase2 ribonuclease A family member 2 increases expression ISO Cytarabine results in increased expression of RNASE2 mRNA CTD PMID:19194470 NCBI chr15:28,154,482...28,155,291
Ensembl chr15:28,154,482...28,155,291
JBrowse link
G Robo3 roundabout guidance receptor 3 increases expression ISO Cytarabine results in increased expression of ROBO3 mRNA CTD PMID:21198554 NCBI chr 8:39,892,792...39,923,735
Ensembl chr 8:39,892,792...39,907,478
JBrowse link
G Rpp25 ribonuclease P and MRP subunit p25 decreases expression ISO Cytarabine results in decreased expression of RPP25 mRNA CTD PMID:21198554 NCBI chr 8:62,283,336...62,284,716
Ensembl chr 8:62,283,336...62,284,716
JBrowse link
G Rprml reprimo-like increases expression ISO Cytarabine results in increased expression of RPRML mRNA CTD PMID:21198554 NCBI chr10:91,710,495...91,711,499
Ensembl chr10:91,710,495...91,711,499
JBrowse link
G Rras RAS related decreases expression ISO Cytarabine results in decreased expression of RRAS mRNA CTD PMID:21198554 NCBI chr 1:101,012,822...101,016,720
Ensembl chr 1:101,012,822...101,016,720
JBrowse link
G Rrm2 ribonucleotide reductase regulatory subunit M2 increases expression ISO Cytarabine results in increased expression of RRM2 mRNA CTD PMID:19194470 NCBI chr 6:43,884,627...43,890,818
Ensembl chr 6:43,884,678...43,889,515
JBrowse link
G Rspo2 R-spondin 2 decreases expression ISO Cytarabine results in decreased expression of RSPO2 mRNA CTD PMID:21198554 NCBI chr 7:81,919,911...82,059,659
Ensembl chr 7:81,924,050...82,059,789
JBrowse link
G Rsrp1 arginine and serine rich protein 1 decreases expression ISO Cytarabine results in decreased expression of RSRP1 mRNA CTD PMID:21198554 NCBI chr 5:153,260,930...153,264,669
Ensembl chr 5:153,260,930...153,264,669
JBrowse link
G Rtn1 reticulon 1 increases expression ISO Cytarabine results in increased expression of RTN1 mRNA CTD PMID:21198554 NCBI chr 6:94,951,016...95,177,477
Ensembl chr 6:94,951,020...95,061,174
JBrowse link
G Rwdd1 RWD domain containing 1 increases expression ISO Cytarabine results in increased expression of RWDD1 mRNA CTD PMID:21198554 NCBI chr20:27,534,361...27,552,225
Ensembl chr20:27,535,324...27,552,349
JBrowse link
G S100a10 S100 calcium binding protein A10 decreases expression ISO Cytarabine results in decreased expression of S100A10 mRNA CTD PMID:21198554 NCBI chr 2:193,892,589...193,901,236
Ensembl chr 2:193,892,589...193,901,236
JBrowse link
G S100a4 S100 calcium-binding protein A4 decreases expression ISO Cytarabine results in decreased expression of S100A4 mRNA CTD PMID:21198554 NCBI chr 2:189,997,278...189,999,587
Ensembl chr 2:189,997,129...189,999,604
JBrowse link
G Saraf store-operated calcium entry-associated regulatory factor decreases expression ISO Cytarabine results in decreased expression of SARAF mRNA CTD PMID:21198554 NCBI chr16:61,735,189...61,753,438
Ensembl chr16:61,735,181...61,753,476
JBrowse link
G Sbspon somatomedin B and thrombospondin, type 1 domain containing decreases expression ISO Cytarabine results in decreased expression of SBSPON mRNA CTD PMID:21198554 NCBI chr 5:2,813,004...2,847,697
Ensembl chr 5:2,813,131...2,843,483
JBrowse link
G Scamp5 secretory carrier membrane protein 5 increases expression ISO Cytarabine results in increased expression of SCAMP5 mRNA CTD PMID:21198554 NCBI chr 8:62,221,820...62,266,269
Ensembl chr 8:62,220,892...62,248,017
JBrowse link
G Scyl1 SCY1 like pseudokinase 1 decreases expression ISO Cytarabine results in decreased expression of SCYL1 mRNA CTD PMID:21198554 NCBI chr 1:221,115,992...221,129,668
Ensembl chr 1:221,115,860...221,129,654
JBrowse link
G Sdc4 syndecan 4 decreases expression ISO Cytarabine results in decreased expression of SDC4 mRNA CTD PMID:21198554 NCBI chr 3:160,872,503...160,891,190
Ensembl chr 3:160,872,503...160,891,190
JBrowse link
G Sec14l1 SEC14-like lipid binding 1 decreases expression ISO Cytarabine results in decreased expression of SEC14L1 mRNA CTD PMID:21198554 NCBI chr10:106,065,712...106,112,859
Ensembl chr10:106,065,712...106,112,857
JBrowse link
G Selenom selenoprotein M decreases expression ISO Cytarabine results in decreased expression of SELENOM mRNA CTD PMID:21198554 NCBI chr14:83,752,393...83,754,975
Ensembl chr14:83,752,393...83,754,973
JBrowse link
G Sema5b semaphorin 5B increases expression ISO Cytarabine results in increased expression of SEMA5B mRNA CTD PMID:21198554 NCBI chr11:68,304,844...68,435,109
Ensembl chr11:68,306,659...68,349,238
JBrowse link
G Serpina1 serpin family A member 1 increases expression ISO Cytarabine results in increased expression of SERPINA1 mRNA CTD PMID:19194470 NCBI chr 6:127,610,241...127,632,265
Ensembl chr 6:127,610,243...127,632,265
JBrowse link
G Serpinb6a serpin family B member 6A decreases expression ISO Cytarabine results in decreased expression of SERPINB6 mRNA CTD PMID:21198554 NCBI chr17:32,154,747...32,209,598
Ensembl chr17:32,190,801...32,209,590
JBrowse link
G Serpinb9 serpin family B member 9 decreases expression ISO Cytarabine results in decreased expression of SERPINB9 mRNA CTD PMID:21198554 NCBI chr17:32,648,846...32,673,047
Ensembl chr17:32,650,441...32,661,865
JBrowse link
G Serpinh1 serpin family H member 1 decreases expression ISO Cytarabine results in decreased expression of SERPINH1 mRNA CTD PMID:21198554 NCBI chr 1:164,301,010...164,308,306
Ensembl chr 1:164,301,010...164,308,317
JBrowse link
G Sertad1 SERTA domain containing 1 decreases expression ISO Cytarabine results in decreased expression of SERTAD1 mRNA CTD PMID:21198554 NCBI chr 1:84,293,102...84,296,370
Ensembl chr 1:84,293,102...84,296,367
JBrowse link
G Sfn stratifin decreases response to substance ISO SFN protein results in decreased susceptibility to Cytarabine CTD PMID:25189999 NCBI chr 5:151,823,422...151,824,937
Ensembl chr 5:151,823,887...151,824,633
JBrowse link
G Sfrp1 secreted frizzled-related protein 1 increases expression ISO Cytarabine results in increased expression of SFRP1 mRNA CTD PMID:21198554 NCBI chr16:73,372,007...73,410,777
Ensembl chr16:73,372,007...73,410,777
JBrowse link
G Sfrp2 secreted frizzled-related protein 2 increases expression ISO Cytarabine results in increased expression of SFRP2 mRNA CTD PMID:21198554 NCBI chr 2:182,723,732...182,731,277
Ensembl chr 2:182,723,854...182,731,764
JBrowse link
G Sgip1 SH3GL interacting endocytic adaptor 1 increases expression ISO Cytarabine results in increased expression of SGIP1 mRNA CTD PMID:21198554 NCBI chr 5:122,300,415...122,498,478
Ensembl chr 5:122,390,522...122,491,203
JBrowse link
G Sh3rf2 SH3 domain containing ring finger 2 decreases expression ISO Cytarabine results in decreased expression of SH3RF2 mRNA CTD PMID:21198554 NCBI chr18:36,371,041...36,471,020
Ensembl chr18:36,371,041...36,471,015
JBrowse link
G Sipa1l2 signal-induced proliferation-associated 1 like 2 decreases expression ISO Cytarabine results in decreased expression of SIPA1L2 mRNA CTD PMID:21198554 NCBI chr19:58,236,201...58,399,842
Ensembl chr19:58,236,214...58,399,816
JBrowse link
G Sla src-like adaptor increases expression ISO Cytarabine results in increased expression of SLA mRNA CTD PMID:19194470 NCBI chr 7:107,585,055...107,604,950
Ensembl chr 7:107,584,118...107,634,335
JBrowse link
G Slc16a3 solute carrier family 16 member 3 decreases expression ISO Cytarabine results in decreased expression of SLC16A3 mRNA CTD PMID:21198554 NCBI chr10:110,138,519...110,148,360
Ensembl chr10:110,138,586...110,148,358
JBrowse link
G Slc16a9 solute carrier family 16, member 9 increases expression ISO Cytarabine results in increased expression of SLC16A9 mRNA CTD PMID:21198554 NCBI chr20:19,634,280...19,675,358 JBrowse link
G Slc17a6 solute carrier family 17 member 6 increases expression ISO Cytarabine results in increased expression of SLC17A6 mRNA CTD PMID:21198554 NCBI chr 1:106,980,463...107,038,717
Ensembl chr 1:106,998,623...107,038,704
JBrowse link
G Slc28a1 solute carrier family 28 member 1 multiple interactions ISO
EXP
Cytarabine inhibits the reaction [SLC28A1 protein results in increased transport of Uridine]
Cytarabine inhibits the reaction [SLC28A1 protein results in increased uptake of Uridine]
CTD PMID:8713072, PMID:10772724 NCBI chr 1:142,948,942...142,992,410
Ensembl chr 1:142,950,540...142,992,615
JBrowse link
G Slc29a1 solute carrier family 29 member 1 decreases response to substance ISO SLC29A1 gene polymorphism results in decreased susceptibility to Cytarabine CTD PMID:18381442 NCBI chr 9:17,784,468...17,799,008
Ensembl chr 9:17,784,468...17,799,005
JBrowse link
G Slc2a1 solute carrier family 2 member 1 decreases expression ISO Cytarabine results in decreased expression of SLC2A1 mRNA CTD PMID:21198554 NCBI chr 5:138,154,677...138,182,897
Ensembl chr 5:138,154,673...138,182,897
JBrowse link
G Slc39a2 solute carrier family 39 member 2 decreases expression ISO Cytarabine results in decreased expression of SLC39A2 mRNA CTD PMID:21198554 NCBI chr15:28,295,044...28,297,688
Ensembl chr15:28,295,368...28,297,684
JBrowse link
G Slc40a1 solute carrier family 40 member 1 decreases expression ISO Cytarabine results in decreased expression of SLC40A1 mRNA CTD PMID:21198554 NCBI chr 9:52,819,451...52,830,461
Ensembl chr 9:52,894,365...52,912,293
JBrowse link
G Slc43a3 solute carrier family 43, member 3 increases expression ISO Cytarabine results in increased expression of SLC43A3 mRNA CTD PMID:19194470 NCBI chr 3:72,328,912...72,351,039
Ensembl chr 3:72,329,967...72,351,111
JBrowse link
G Slc47a1 solute carrier family 47 member 1 decreases expression ISO Cytarabine results in decreased expression of SLC47A1 mRNA CTD PMID:21198554 NCBI chr10:47,631,425...47,685,379
Ensembl chr10:47,632,192...47,666,921
JBrowse link
G Slc4a8 solute carrier family 4 member 8 decreases expression ISO Cytarabine results in decreased expression of SLC4A8 mRNA CTD PMID:21198554 NCBI chr 7:142,397,352...142,467,398
Ensembl chr 7:142,397,371...142,464,158
JBrowse link
G Slc5a12 solute carrier family 5 member 12 decreases expression ISO Cytarabine results in decreased expression of SLC5A12 mRNA CTD PMID:21198554 NCBI chr 3:101,791,336...101,833,044
Ensembl chr 3:101,791,337...101,833,044
JBrowse link
G Slc7a2 solute carrier family 7 member 2 decreases expression ISO Cytarabine results in decreased expression of SLC7A2 mRNA CTD PMID:21198554 NCBI chr16:54,459,409...54,513,349
Ensembl chr16:54,460,067...54,513,349