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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:vincamine
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Accession:CHEBI:9985 term browser browse the term
Definition:An alkaloid ester that has formula C21H26N2O3.
Synonyms:exact_synonym: methyl 14beta-hydroxy-14,15-dihydro-3alpha,16alpha-eburnamenine-14alpha-carboxylate
 related_synonym: Formula=C21H26N2O3;   InChI=1S/C21H26N2O3/c1-3-20-10-6-11-22-12-9-15-14-7-4-5-8-16(14)23(17(15)18(20)22)21(25,13-20)19(24)26-2/h4-5,7-8,18,25H,3,6,9-13H2,1-2H3/t18-,20+,21+/m1/s1;   InChIKey=RXPRRQLKFXBCSJ-GIVPXCGWSA-N;   Methyl vincaminate;   Pervincamine;   SMILES=[H][C@]12N3CCC[C@@]1(CC)C[C@](O)(C(=O)OC)n1c2c(CC3)c2ccccc12;   Vincamidol
 xref: Beilstein:52767;   CAS:1617-90-9;   Drug_Central:3643;   KEGG:C09251;   KEGG:D08677;   KNApSAcK:C00001782;   LINCS:LSM-2907
 xref_mesh: MESH:D014749


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vincamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO Vincamine results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:7,355,066...7,387,282
Ensembl chr 4:7,355,574...7,387,253
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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19787
    role 19734
      biological role 19734
        biochemical role 19282
          metabolite 19263
            vincamine 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19787
    subatomic particle 19784
      composite particle 19784
        hadron 19784
          baryon 19784
            nucleon 19784
              atomic nucleus 19784
                atom 19784
                  main group element atom 19672
                    p-block element atom 19672
                      carbon group element atom 19574
                        carbon atom 19563
                          organic molecular entity 19563
                            organic group 18495
                              cyclic organic group 1830
                                organic heterobicyclic ring 1830
                                  indole skeleton 1830
                                    indole alkaloid 1830
                                      terpenoid indole alkaloid 1463
                                        monoterpenoid indole alkaloid 1454
                                          vinca alkaloid 1314
                                            vincamine 1
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