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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:vincamine
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Accession:CHEBI:9985 term browser browse the term
Definition:An alkaloid ester that has formula C21H26N2O3.
Synonyms:exact_synonym: methyl 14beta-hydroxy-14,15-dihydro-3alpha,16alpha-eburnamenine-14alpha-carboxylate
 related_synonym: Formula=C21H26N2O3;   InChI=1S/C21H26N2O3/c1-3-20-10-6-11-22-12-9-15-14-7-4-5-8-16(14)23(17(15)18(20)22)21(25,13-20)19(24)26-2/h4-5,7-8,18,25H,3,6,9-13H2,1-2H3/t18-,20+,21+/m1/s1;   InChIKey=RXPRRQLKFXBCSJ-GIVPXCGWSA-N;   Methyl vincaminate;   Pervincamine;   SMILES=[H][C@]12N3CCC[C@@]1(CC)C[C@](O)(C(=O)OC)n1c2c(CC3)c2ccccc12;   Vincamidol
 xref: Beilstein:52767;   CAS:1617-90-9;   Drug_Central:3643;   KEGG:C09251;   KEGG:D08677;   KNApSAcK:C00001782;   LINCS:LSM-2907
 xref_mesh: MESH:D014749



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vincamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO Vincamine results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008
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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19918
    role 19894
      biological role 19892
        biochemical role 19588
          metabolite 19574
            vincamine 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19918
    subatomic particle 19916
      composite particle 19916
        hadron 19916
          baryon 19916
            nucleon 19916
              atomic nucleus 19916
                atom 19916
                  main group element atom 19866
                    p-block element atom 19866
                      carbon group element atom 19811
                        carbon atom 19806
                          organic molecular entity 19806
                            organic group 18995
                              cyclic organic group 1945
                                organic heterobicyclic ring 1945
                                  indole skeleton 1945
                                    indole alkaloid 1945
                                      terpenoid indole alkaloid 1501
                                        monoterpenoid indole alkaloid 1483
                                          vinca alkaloid 1344
                                            vincamine 1
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