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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:perindopril
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Accession:CHEBI:8024 term browser browse the term
Definition:An alpha-amino acid ester that is the ethyl ester of N-{(2S)-1-[(2S,3aS,7aS)-2-carboxyoctahydro-1H-indol-1-yl]-1-oxopropan-2-yl}-L-norvaline
Synonyms:exact_synonym: ethyl N-{(2S)-1-[(2S,3aS,7aS)-2-carboxyoctahydro-1H-indol-1-yl]-1-oxopropan-2-yl}-L-norvalinate
 related_synonym: (2S,3aS,7aS)-1-[(2S)-2-{[(2S)-1-ethoxy-1-oxopentan-2-yl]amino}propanoyl]octahydro-1H-indole-2-carboxylic acid;   Formula=C19H32N2O5;   InChI=1S/C19H32N2O5/c1-4-8-14(19(25)26-5-2)20-12(3)17(22)21-15-10-7-6-9-13(15)11-16(21)18(23)24/h12-16,20H,4-11H2,1-3H3,(H,23,24)/t12-,13-,14-,15-,16-/m0/s1;   InChIKey=IPVQLZZIHOAWMC-QXKUPLGCSA-N;   SMILES=[H][C@@]12CCCC[C@]1([H])N([C@@H](C2)C(O)=O)C(=O)[C@H](C)N[C@@H](CCC)C(=O)OCC;   perindoprilum
 xref: CAS:82834-16-0;   DrugBank:DB00790;   Drug_Central:2108;   HMDB:HMDB0014928;   KEGG:C07706;   KEGG:D03753;   LINCS:LSM-4080
 xref_mesh: MESH:D020913
 xref: PMID:24291100;   PMID:24324048;   PMID:24357222;   PMID:24511479;   PMID:24515310;   PMID:24554346;   PMID:24590580;   PMID:24602481;   PMID:24664905;   Reaxys:4300272;   Wikipedia:Perindopril
 cyclic_relationship: is_conjugate_acid_of CHEBI:78000

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perindopril term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme affects response to substance ISO ACE gene polymorphism affects the susceptibility to Perindopril CTD PMID:11007831 NCBI chr10:94,170,766...94,213,831
Ensembl chr10:94,170,766...94,187,822 		JBrowse link
G Ace2 angiotensin I converting enzyme 2 multiple interactions EXP Perindopril promotes the reaction [Carbon Tetrachloride results in increased expression of ACE2 mRNA]; Perindopril promotes the reaction [Carbon Tetrachloride results in increased expression of ACE2 protein] CTD PMID:19793108 NCBI chr  X:32,050,734...32,095,860
Ensembl chr  X:32,049,931...32,096,016 		JBrowse link
G Acta2 actin alpha 2, smooth muscle decreases expression
multiple interactions		 EXP Perindopril results in decreased expression of ACTA2 protein
[Imatinib Mesylate co-treated with Perindopril] inhibits the reaction [Carbon Tetrachloride affects the expression of ACTA2 mRNA]; Perindopril inhibits the reaction [Carbon Tetrachloride affects the expression of ACTA2 mRNA]		 CTD PMID:12076858 PMID:16596278 NCBI chr 1:252,537,614...252,550,394
Ensembl chr 1:252,537,615...252,550,394 		JBrowse link
G Afp alpha-fetoprotein multiple interactions ISO Perindopril inhibits the reaction [Diethylnitrosamine results in increased expression of AFP protein] CTD PMID:29859236 NCBI chr14:19,141,755...19,159,919
Ensembl chr14:19,141,755...19,159,923 		JBrowse link
G Agt angiotensinogen decreases expression
increases expression
multiple interactions		 ISO
EXP		 Perindopril results in decreased expression of AGT protein alternative form
Perindopril results in increased expression of AGT protein alternative form
[Perindopril co-treated with racecadotril] results in increased expression of AGT protein alternative form		 CTD PMID:2549899 PMID:2605800 PMID:9808682 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433 		JBrowse link
G Agtr1a angiotensin II receptor, type 1a affects response to substance
multiple interactions		 ISO
EXP		 AGTR1 gene SNP affects the susceptibility to Perindopril
[Perindopril co-treated with AM6545] inhibits the reaction [Streptozocin results in increased expression of AGTR1A protein]; Perindopril inhibits the reaction [Streptozocin results in increased expression of AGTR1A mRNA]; Perindopril inhibits the reaction [Streptozocin results in increased expression of AGTR1A protein]
Perindopril inhibits the reaction [Carbon Tetrachloride results in increased expression of AGTR1A mRNA]; Perindopril inhibits the reaction [Carbon Tetrachloride results in increased expression of AGTR1A protein]		 CTD PMID:8952600 PMID:12930639 PMID:16097048 PMID:30184259 NCBI chr17:35,907,102...35,958,136
Ensembl chr17:35,907,108...35,958,077 		JBrowse link
G Alb albumin multiple interactions EXP
ISO		 Perindopril inhibits the reaction [Carbon Tetrachloride results in decreased expression of ALB protein]
Perindopril inhibits the reaction [Streptozocin results in increased expression of ALB protein]		 CTD PMID:16872305 PMID:30184259 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863 		JBrowse link
G Arg1 arginase 1 multiple interactions ISO Perindopril inhibits the reaction [AM6545 inhibits the reaction [Streptozocin results in decreased expression of ARG1 mRNA]] CTD PMID:30184259 NCBI chr 1:21,525,421...21,537,872
Ensembl chr 1:21,525,421...21,537,863 		JBrowse link
G Bcl2l1 Bcl2-like 1 multiple interactions EXP Perindopril inhibits the reaction [Isoproterenol results in increased expression of BCL2L1 mRNA alternative form] CTD PMID:16116328 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810 		JBrowse link
G Bdkrb1 bradykinin receptor B1 affects expression EXP Perindopril affects the expression of BDKRB1 protein CTD PMID:18806609 NCBI chr 6:129,437,423...129,441,553
Ensembl chr 6:129,438,158...129,440,574 		JBrowse link
G Bdkrb2 bradykinin receptor B2 affects expression EXP Perindopril affects the expression of BDKRB2 protein CTD PMID:18806609 NCBI chr 6:129,399,468...129,429,676
Ensembl chr 6:129,399,468...129,429,676 		JBrowse link
G Cat catalase increases activity EXP Perindopril results in increased activity of CAT protein CTD PMID:26878793 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 decreases expression
multiple interactions		 ISO Perindopril results in decreased expression of CCL2 protein
[AM6545 co-treated with Perindopril] inhibits the reaction [Streptozocin results in increased expression of CCL2 mRNA]; [AM6545 co-treated with Perindopril] inhibits the reaction [Streptozocin results in increased expression of CCL2 protein]		 CTD PMID:19840533 PMID:30184259 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870 		JBrowse link
G Ccl3 C-C motif chemokine ligand 3 multiple interactions ISO AM6545 promotes the reaction [Perindopril inhibits the reaction [Streptozocin results in increased expression of CCL3 mRNA]]; Perindopril inhibits the reaction [Streptozocin results in increased expression of CCL3 mRNA]; Perindopril promotes the reaction [AM6545 inhibits the reaction [Streptozocin results in increased expression of CCL3 mRNA]] CTD PMID:30184259 NCBI chr10:70,869,516...70,871,066
Ensembl chr10:70,869,513...70,871,066 		JBrowse link
G Ccnd1 cyclin D1 multiple interactions ISO Perindopril inhibits the reaction [Diethylnitrosamine results in increased expression of CCND1 mRNA] CTD PMID:29859236 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325 		JBrowse link
G Ccr2 C-C motif chemokine receptor 2 multiple interactions ISO [AM6545 co-treated with Perindopril] inhibits the reaction [Streptozocin results in increased expression of CCR2 mRNA]; Perindopril inhibits the reaction [Streptozocin results in increased expression of CCR2 mRNA] CTD PMID:30184259
G Cd163 CD163 molecule multiple interactions ISO AM6545 promotes the reaction [Perindopril inhibits the reaction [Streptozocin results in decreased expression of CD163 mRNA]]; Perindopril inhibits the reaction [Streptozocin results in decreased expression of CD163 mRNA]; Perindopril promotes the reaction [AM6545 inhibits the reaction [Streptozocin results in decreased expression of CD163 mRNA]] CTD PMID:30184259 NCBI chr 4:156,752,063...156,785,467
Ensembl chr 4:156,752,082...156,785,467 		JBrowse link
G Cd68 Cd68 molecule multiple interactions ISO AM6545 promotes the reaction [Perindopril inhibits the reaction [Streptozocin results in increased expression of CD68 mRNA]]; Perindopril inhibits the reaction [Streptozocin results in increased expression of CD68 mRNA]; Perindopril promotes the reaction [AM6545 inhibits the reaction [Streptozocin results in increased expression of CD68 mRNA]] CTD PMID:30184259 NCBI chr10:56,268,726...56,270,605
Ensembl chr10:56,268,720...56,270,640 		JBrowse link
G Col1a2 collagen type I alpha 2 chain multiple interactions EXP [Imatinib Mesylate co-treated with Perindopril] inhibits the reaction [Carbon Tetrachloride affects the expression of COL1A2 mRNA]; Perindopril inhibits the reaction [Carbon Tetrachloride affects the expression of COL1A2 mRNA] CTD PMID:16596278 NCBI chr 4:31,534,225...31,569,152
Ensembl chr 4:31,534,225...31,569,151 		JBrowse link
G Col3a1 collagen type III alpha 1 chain decreases expression EXP Perindopril results in decreased expression of COL3A1 mRNA CTD PMID:12076858 PMID:14871039 NCBI chr 9:52,023,295...52,059,221
Ensembl chr 9:52,023,295...52,059,217 		JBrowse link
G Fn1 fibronectin 1 multiple interactions ISO [AM6545 co-treated with Perindopril] inhibits the reaction [Streptozocin results in increased expression of FN1 mRNA]; Perindopril inhibits the reaction [Streptozocin results in increased expression of FN1 mRNA]; Perindopril inhibits the reaction [Streptozocin results in increased expression of FN1 protein] CTD PMID:30184259 NCBI chr 9:78,900,111...78,969,018
Ensembl chr 9:78,900,103...78,969,078 		JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions ISO Perindopril inhibits the reaction [Diethylnitrosamine results in increased activity of GPT protein] CTD PMID:29859236 NCBI chr 7:117,759,083...117,761,932
Ensembl chr 7:117,759,083...117,761,931 		JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO AM6545 promotes the reaction [Perindopril inhibits the reaction [Streptozocin results in increased expression of ICAM1 mRNA]]; AM6545 promotes the reaction [Perindopril inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]]; Perindopril inhibits the reaction [Streptozocin results in increased expression of ICAM1 mRNA]; Perindopril inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]; Perindopril promotes the reaction [AM6545 inhibits the reaction [Streptozocin results in increased expression of ICAM1 mRNA]]; Perindopril promotes the reaction [AM6545 inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]] CTD PMID:30184259 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059 		JBrowse link
G Il10 interleukin 10 increases expression ISO Perindopril results in increased expression of IL10 protein CTD PMID:19840533 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392 		JBrowse link
G Il1b interleukin 1 beta decreases expression ISO Perindopril results in decreased expression of IL1B protein CTD PMID:19840533 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726 		JBrowse link
G Il6 interleukin 6 decreases expression ISO Perindopril results in decreased expression of IL6 protein CTD PMID:19840533 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807 		JBrowse link
G Kng2 kininogen 2 decreases expression
increases expression
multiple interactions		 ISO
EXP		 Perindopril results in decreased expression of KNG1 protein modified form
Perindopril results in increased expression of KNG1 protein alternative form
Perindopril promotes the reaction [racecadotril affects the metabolism of KNG1 protein alternative form]		 CTD PMID:9808682 PMID:11855668 NCBI chr11:81,509,185...81,516,759 JBrowse link
G Lep leptin decreases expression EXP Perindopril results in decreased expression of LEP protein CTD PMID:18083506 NCBI chr 4:56,337,695...56,351,818
Ensembl chr 4:56,337,695...56,351,818 		JBrowse link
G Mas1 MAS1 proto-oncogene, G protein-coupled receptor multiple interactions EXP Perindopril promotes the reaction [Carbon Tetrachloride results in increased expression of MAS1 mRNA] CTD PMID:19793108 NCBI chr 1:48,076,761...48,108,218
Ensembl chr 1:48,077,033...48,108,216 		JBrowse link
G Mfn2 mitofusin 2 increases expression EXP Perindopril results in increased expression of MFN2 mRNA; Perindopril results in increased expression of MFN2 protein CTD PMID:25464244 NCBI chr 5:164,684,244...164,715,414
Ensembl chr 5:164,684,509...164,714,145 		JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions EXP
ISO		 Perindopril inhibits the reaction [Carbon Tetrachloride results in increased activity of MMP2 protein]
Perindopril inhibits the reaction [Diethylnitrosamine results in increased expression of MMP2 protein]		 CTD PMID:12930639 PMID:14761280 PMID:16097048 PMID:29859236 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611 		JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions EXP Perindopril inhibits the reaction [Carbon Tetrachloride results in increased activity of MMP9 protein] CTD PMID:16097048 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520 		JBrowse link
G Mrc1 mannose receptor, C type 1 multiple interactions ISO AM6545 promotes the reaction [Perindopril inhibits the reaction [Streptozocin results in decreased expression of MRC1 mRNA]]; Perindopril inhibits the reaction [Streptozocin results in decreased expression of MRC1 mRNA]; Perindopril promotes the reaction [AM6545 inhibits the reaction [Streptozocin results in decreased expression of MRC1 mRNA]] CTD PMID:30184259 NCBI chr17:81,352,700...81,433,743
Ensembl chr17:81,352,700...81,433,743 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO Perindopril inhibits the reaction [Diethylnitrosamine results in decreased expression of NFKB1 protein] CTD PMID:29859236 NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO AM6545 promotes the reaction [Perindopril inhibits the reaction [Streptozocin results in increased expression of NOS2 mRNA]]; Perindopril inhibits the reaction [Streptozocin results in increased expression of NOS2 mRNA]; Perindopril promotes the reaction [AM6545 inhibits the reaction [Streptozocin results in increased expression of NOS2 mRNA]] CTD PMID:30184259 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190 		JBrowse link
G Nphs1 NPHS1 adhesion molecule, nephrin multiple interactions ISO AM6545 promotes the reaction [Perindopril inhibits the reaction [Streptozocin results in decreased expression of NPHS1 mRNA]]; AM6545 promotes the reaction [Perindopril inhibits the reaction [Streptozocin results in decreased expression of NPHS1 protein]]; Perindopril inhibits the reaction [Streptozocin results in decreased expression of NPHS1 mRNA]; Perindopril inhibits the reaction [Streptozocin results in decreased expression of NPHS1 protein]; Perindopril promotes the reaction [AM6545 inhibits the reaction [Streptozocin results in decreased expression of NPHS1 mRNA]]; Perindopril promotes the reaction [AM6545 inhibits the reaction [Streptozocin results in decreased expression of NPHS1 protein]] CTD PMID:30184259 NCBI chr 1:88,922,346...88,950,560
Ensembl chr 1:88,922,433...88,950,559 		JBrowse link
G Nphs2 NPHS2 stomatin family member, podocin multiple interactions ISO AM6545 promotes the reaction [Perindopril inhibits the reaction [Streptozocin results in decreased expression of NPHS2 mRNA]]; AM6545 promotes the reaction [Perindopril inhibits the reaction [Streptozocin results in decreased expression of NPHS2 protein]]; Perindopril inhibits the reaction [Streptozocin results in decreased expression of NPHS2 mRNA]; Perindopril inhibits the reaction [Streptozocin results in decreased expression of NPHS2 protein]; Perindopril promotes the reaction [AM6545 inhibits the reaction [Streptozocin results in decreased expression of NPHS2 mRNA]]; Perindopril promotes the reaction [AM6545 inhibits the reaction [Streptozocin results in decreased expression of NPHS2 protein]] CTD PMID:30184259 NCBI chr13:73,929,136...73,941,522
Ensembl chr13:73,929,136...73,941,522 		JBrowse link
G Pdgfb platelet derived growth factor subunit B multiple interactions EXP Perindopril inhibits the reaction [Carbon Tetrachloride results in increased expression of [PDGFB protein binds to PDGFB protein]]; Perindopril inhibits the reaction [Carbon Tetrachloride results in increased expression of PDGFB protein] CTD PMID:12930639 PMID:14761280 PMID:16097048 NCBI chr 7:121,215,458...121,233,092
Ensembl chr 7:121,214,628...121,232,741 		JBrowse link
G Ppp3ca protein phosphatase 3 catalytic subunit alpha decreases expression EXP Perindopril results in decreased expression of PPP3CA protein CTD PMID:18344631 NCBI chr 2:241,909,332...242,186,861
Ensembl chr 2:241,909,832...242,184,854 		JBrowse link
G Ppp3r1 protein phosphatase 3, regulatory subunit B, alpha decreases expression EXP Perindopril results in decreased expression of PPP3R1 mRNA CTD PMID:18344631 NCBI chr14:100,311,224...100,360,879
Ensembl chr14:100,311,173...100,360,879 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO Perindopril inhibits the reaction [Diethylnitrosamine results in increased phosphorylation of RELA protein] CTD PMID:29859236 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249 		JBrowse link
G Ren renin increases expression
increases activity		 EXP
ISO		 Perindopril results in increased expression of REN protein
Perindopril results in increased activity of REN protein		 CTD PMID:2549899 PMID:2605800 PMID:9383173 NCBI chr13:50,502,724...50,513,953
Ensembl chr13:50,502,724...50,514,151 		JBrowse link
G Ryr2 ryanodine receptor 2 multiple interactions
increases expression		 EXP carvedilol promotes the reaction [Perindopril results in increased expression of RYR2 protein]; Perindopril promotes the reaction [carvedilol results in increased expression of RYR2 protein] CTD PMID:19620082 NCBI chr17:65,533,998...65,955,606
Ensembl chr17:65,535,403...65,955,606 		JBrowse link
G Sfrp4 secreted frizzled-related protein 4 affects binding ISO Perindopril binds to SFRP4 protein CTD PMID:25019556 NCBI chr17:47,383,983...47,394,065
Ensembl chr17:47,297,489...47,394,328 		JBrowse link
G Slc15a1 solute carrier family 15 member 1 multiple interactions ISO Perindopril inhibits the reaction [SLC15A1 protein results in increased uptake of glycylsarcosine] CTD PMID:18713951 NCBI chr15:106,800,081...106,844,668
Ensembl chr15:106,800,081...106,844,426 		JBrowse link
G Slc15a2 solute carrier family 15 member 2 multiple interactions EXP Perindopril inhibits the reaction [SLC15A2 protein results in increased uptake of glycylsarcosine] CTD PMID:18713951 NCBI chr11:66,932,664...66,961,708
Ensembl chr11:66,932,614...66,961,713 		JBrowse link
G Smad3 SMAD family member 3 multiple interactions
decreases expression		 EXP Perindopril inhibits the reaction [Carbon Tetrachloride results in increased expression of SMAD3 protein]
Perindopril results in decreased expression of SMAD3 protein		 CTD PMID:15619341 PMID:16872305 NCBI chr 8:68,569,530...68,678,349
Ensembl chr 8:68,569,530...68,678,349 		JBrowse link
G Smad7 SMAD family member 7 increases expression
multiple interactions		 EXP Perindopril results in increased expression of SMAD7 protein
Perindopril inhibits the reaction [Carbon Tetrachloride results in decreased expression of SMAD7 protein]		 CTD PMID:15619341 PMID:16872305 NCBI chr18:71,395,830...71,424,164
Ensembl chr18:71,395,830...71,424,157 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions
decreases expression		 EXP
ISO		 Perindopril inhibits the reaction [Carbon Tetrachloride affects the expression of TGFB1 mRNA]; Perindopril inhibits the reaction [Carbon Tetrachloride results in increased expression of TGFB1 mRNA]; Perindopril inhibits the reaction [Carbon Tetrachloride results in increased expression of TGFB1 protein]
Perindopril inhibits the reaction [Diethylnitrosamine results in increased expression of TGFB1 protein]
Perindopril results in decreased expression of TGFB1 mRNA; Perindopril results in decreased expression of TGFB1 protein		 CTD PMID:12930639 PMID:14761280 PMID:14871039 PMID:15619341 PMID:16097048 PMID:16596278 PMID:16872305 PMID:29859236 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199 		JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 decreases expression
multiple interactions		 EXP Perindopril results in decreased expression of TGFBR2 mRNA
Perindopril inhibits the reaction [Carbon Tetrachloride results in increased expression of TGFBR2 mRNA]		 CTD PMID:15619341 PMID:16872305 NCBI chr 8:124,310,288...124,399,345
Ensembl chr 8:124,312,754...124,399,494 		JBrowse link
G Tnf tumor necrosis factor decreases expression
multiple interactions
increases expression		 ISO
EXP		 Perindopril results in decreased expression of TNF protein
AM6545 promotes the reaction [Perindopril inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]]; AM6545 promotes the reaction [Perindopril inhibits the reaction [Streptozocin results in increased expression of TNF protein]]; Perindopril inhibits the reaction [Diethylnitrosamine results in increased expression of TNF protein]; Perindopril inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]; Perindopril inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Perindopril promotes the reaction [AM6545 inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]]; Perindopril promotes the reaction [AM6545 inhibits the reaction [Streptozocin results in increased expression of TNF protein]]
Perindopril results in increased expression of TNF protein		 CTD PMID:19840533 PMID:26878793 PMID:29859236 PMID:30184259 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000 		JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions ISO Perindopril inhibits the reaction [Diethylnitrosamine results in increased expression of VEGFA protein] CTD PMID:29859236 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681 		JBrowse link
G Vwf von Willebrand factor decreases expression ISO Perindopril results in decreased expression of VWF protein CTD PMID:12224817 NCBI chr 4:158,085,059...158,219,525
Ensembl chr 4:158,088,505...158,219,523 		JBrowse link
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  CHEBI ontology 19853
    role 19804
      biological role 19804
        antimicrobial agent 17392
          disinfectant 12271
            ethanol 8150
              ethyl ester 3226
                perindopril 53
Path 2
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  CHEBI ontology 19853
    subatomic particle 19851
      composite particle 19851
        hadron 19851
          baryon 19851
            nucleon 19851
              atomic nucleus 19851
                atom 19851
                  main group element atom 19744
                    p-block element atom 19744
                      carbon group element atom 19650
                        carbon atom 19639
                          organic molecular entity 19639
                            organic group 18550
                              organic divalent group 18541
                                organodiyl group 18541
                                  carbonyl group 18447
                                    carbonyl compound 18447
                                      carboxylic acid 18125
                                        amino acid 14110
                                          alpha-amino acid 11593
                                            alpha-amino acid ester 229
                                              perindopril 53
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