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ONTOLOGY REPORT - ANNOTATIONS


Term:gemcitabine
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Accession:CHEBI:175901 term browser browse the term
Definition:A 2'-deoxycytidine having geminal fluoro substituents in the 2'-position. An inhibitor of ribonucleotide reductase, gemcitabine is used in the treatment of various carcinomas, particularly non-small cell lung cancer, pancreatic cancer, bladder cancer and breast cancer.
Synonyms:related_synonym: 2',2'-Difluorodeoxycytidine;   2'-Deoxy-2',2'-difluorocytidine;   4-amino-1-((2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)-tetrahydrofuran-2-yl)pyrimidin-2(1H)-one;   Formula=C9H11F2N3O4;   InChI=1S/C9H11F2N3O4/c10-9(11)6(16)4(3-15)18-7(9)14-2-1-5(12)13-8(14)17/h1-2,4,6-7,15-16H,3H2,(H2,12,13,17)/t4-,6-,7-/m1/s1;   InChIKey=SDUQYLNIPVEERB-QPPQHZFASA-N;   SMILES=Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)C2(F)F)c(=O)n1;   gemcitabina;   gemcitabinum
 alt_id: CHEBI:42752;   CHEBI:5295
 xref: Beilstein:5382060;   CAS:95058-81-4;   DrugBank:DB00441;   Drug_Central:1283;   KEGG:C07650;   KEGG:D02368;   LINCS:LSM-5333
 xref_mesh: MESH:C056507
 xref: PDBeChem:GEO;   PMID:11034044;   PMID:11061612;   PMID:11088063;   PMID:11122828;   PMID:11132538;   PMID:11142482;   PMID:11221019;   PMID:11356111;   PMID:11374818;   PMID:11489002;   PMID:11504793;   PMID:11510027;   PMID:11585734;   PMID:11595724;   PMID:11807603;   PMID:11859947;   PMID:11901308;   PMID:12057041;   PMID:12057046;   PMID:12057157;   PMID:12115355;   PMID:12142097;   PMID:12520460;   PMID:12571808;   PMID:12722678;   PMID:12722691;   PMID:12743987;   PMID:12761494;   PMID:12798170;   PMID:12917815;   PMID:12954073;   PMID:14606642;   PMID:14653877;   PMID:14720338;   PMID:15131028;   PMID:15160243;   PMID:15221904;   PMID:15282439;   PMID:15297392;   PMID:15542781;   PMID:15637766;   PMID:15744590;   PMID:16001951;   PMID:16041610;   PMID:16080557;   PMID:16143373;   PMID:16149285;   PMID:16317298;   PMID:16500746;   PMID:16555971;   PMID:16584929;   PMID:16807461;   PMID:16807463;   PMID:16894289;   PMID:16905983;   PMID:17101674;   PMID:17296311;   PMID:17296587;   PMID:17347561;   PMID:17429628;   PMID:17460420;   PMID:17602464;   PMID:17639396;   PMID:17887663;   PMID:17939651;   PMID:17941128;   PMID:17987263;   PMID:18035967;   PMID:18050344;   PMID:18086345;   PMID:18166944;   PMID:18186604;   PMID:18257544;   PMID:18348652;   PMID:18773046;   PMID:18789834;   PMID:18819792;   PMID:18981552;   PMID:19034448;   PMID:19177022;   PMID:19399788;   PMID:19839926;   PMID:19879060;   PMID:22763439;   PMID:28594276;   PMID:28608357;   PMID:28912244;   Patent:EP1939198;   Patent:EP2108368;   Patent:EP2275135;   Patent:GB2136425;   Patent:US2009124797;   Patent:US2010111852;   Patent:US4808614;   Reaxys:5382060;   Wikipedia:Gemcitabine


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gemcitabine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G A2m alpha-2-macroglobulin JBrowse link 4 154,309,426 154,359,138 RGD:6480464
G Acp3 acid phosphatase 3 JBrowse link 8 112,838,574 112,884,062 RGD:6480464
G Adam17 ADAM metallopeptidase domain 17 JBrowse link 6 43,400,525 43,448,280 RGD:6480464
G Adipoq adiponectin, C1Q and collagen domain containing JBrowse link 11 81,330,845 81,344,488 RGD:6480464
G Afp alpha-fetoprotein JBrowse link 14 19,141,755 19,159,919 RGD:6480464
G Agpat2 1-acylglycerol-3-phosphate O-acyltransferase 2 JBrowse link 3 4,044,741 4,055,384 RGD:6480464
G Akt1 AKT serine/threonine kinase 1 JBrowse link 6 137,218,398 137,239,970 RGD:6480464
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 JBrowse link 1 238,222,689 238,264,381 RGD:6480464
G Aldh1a3 aldehyde dehydrogenase 1 family, member A3 JBrowse link 1 127,302,920 127,337,828 RGD:6480464
G Aldh6a1 aldehyde dehydrogenase 6 family, member A1 JBrowse link 6 108,146,552 108,167,185 RGD:6480464
G Anapc1 anaphase promoting complex subunit 1 JBrowse link 3 121,147,484 121,226,125 RGD:6480464
G Ank3 ankyrin 3 JBrowse link 20 19,948,767 20,480,628 RGD:6480464
G Ankrd1 ankyrin repeat domain 1 JBrowse link 1 254,726,985 254,745,673 RGD:6480464
G Antxr1 ANTXR cell adhesion molecule 1 JBrowse link 4 118,946,267 119,131,202 RGD:6480464
G Apcs amyloid P component, serum JBrowse link 13 91,426,621 91,427,417 RGD:6480464
G Apoh apolipoprotein H JBrowse link 10 96,640,013 96,653,939 RGD:6480464
G Ar androgen receptor JBrowse link X 67,656,253 67,828,998 RGD:6480464
G Areg amphiregulin JBrowse link 14 18,521,921 18,531,179 RGD:6480464
G Arf1 ADP-ribosylation factor 1 JBrowse link 10 45,562,700 45,579,214 RGD:6480464
G Arnt aryl hydrocarbon receptor nuclear translocator JBrowse link 2 196,594,178 196,651,486 RGD:6480464
G Atf3 activating transcription factor 3 JBrowse link 13 109,817,892 109,849,632 RGD:6480464
G Axin2 axin 2 JBrowse link 10 97,212,483 97,238,824 RGD:6480464
G Axl Axl receptor tyrosine kinase JBrowse link 1 82,550,892 82,580,761 RGD:6480464
G Bax BCL2 associated X, apoptosis regulator JBrowse link 1 101,451,801 101,457,207 RGD:6480464
G Bcl2 BCL2, apoptosis regulator JBrowse link 13 26,605,426 26,769,374 RGD:6480464
G Bcl2l1 Bcl2-like 1 JBrowse link 3 148,259,594 148,314,191 RGD:6480464
G Bcl2l11 BCL2 like 11 JBrowse link 3 120,726,906 120,764,192 RGD:6480464
G Bcl6 BCL6, transcription repressor JBrowse link 11 80,255,790 80,279,075 RGD:6480464
G Bdnf brain-derived neurotrophic factor JBrowse link 3 100,768,637 100,819,216 RGD:6480464
G Bid BH3 interacting domain death agonist JBrowse link 4 153,439,812 153,465,247 RGD:6480464
G Birc2 baculoviral IAP repeat-containing 2 JBrowse link 8 6,014,014 6,036,668 RGD:6480464
G Birc3 baculoviral IAP repeat-containing 3 JBrowse link 8 6,048,590 6,076,828 RGD:6480464
G Birc5 baculoviral IAP repeat-containing 5 JBrowse link 10 106,856,097 106,864,419 RGD:6480464
G Bnip3l BCL2 interacting protein 3 like JBrowse link 15 43,643,897 43,667,123 RGD:6480464
G Braf B-Raf proto-oncogene, serine/threonine kinase JBrowse link 4 67,389,331 67,520,549 RGD:6480464
G Brca1 BRCA1, DNA repair associated JBrowse link 10 89,394,821 89,455,093 RGD:6480464
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:6480464
G Casp6 caspase 6 JBrowse link 2 235,341,326 235,353,715 RGD:6480464
G Casp8 caspase 8 JBrowse link 9 65,614,142 65,662,624 RGD:6480464
G Casp9 caspase 9 JBrowse link 5 160,356,211 160,373,774 RGD:6480464
G Ccl2 C-C motif chemokine ligand 2 JBrowse link 10 69,412,065 69,413,863 RGD:6480464
G Ccl20 C-C motif chemokine ligand 20 JBrowse link 9 88,918,359 88,921,017 RGD:6480464
G Ccl3 C-C motif chemokine ligand 3 JBrowse link 10 70,869,516 70,871,066 RGD:6480464
G Ccnb1 cyclin B1 JBrowse link 2 30,782,133 30,791,106 RGD:6480464
G Ccnd1 cyclin D1 JBrowse link 1 218,090,750 218,100,447 RGD:6480464
G Ccng2 cyclin G2 JBrowse link 14 16,267,572 16,276,068 RGD:6480464
G Cd40 CD40 molecule JBrowse link 3 161,519,789 161,534,943 RGD:6480464
G Cd40lg CD40 ligand JBrowse link X 159,703,703 159,714,886 RGD:6480464
G Cda cytidine deaminase JBrowse link 5 156,703,579 156,734,541 RGD:6480464
G Cdc25c cell division cycle 25C JBrowse link 18 27,528,768 27,550,316 RGD:6480464
G Cdh1 cadherin 1 JBrowse link 19 38,768,467 38,838,395 RGD:6480464
G Cdkn1a cyclin-dependent kinase inhibitor 1A JBrowse link 20 6,348,422 6,358,864 RGD:6480464
G Cdkn1b cyclin-dependent kinase inhibitor 1B JBrowse link 4 168,689,043 168,694,159 RGD:6480464
G Cebpb CCAAT/enhancer binding protein beta JBrowse link 3 164,424,502 164,425,933 RGD:6480464
G Chrdl2 chordin-like 2 JBrowse link 1 165,008,997 165,036,431 RGD:6480464
G Ckb creatine kinase B JBrowse link 6 136,142,956 136,145,838 RGD:6480464
G Clic4 chloride intracellular channel 4 JBrowse link 5 153,568,937 153,625,669 RGD:6480464
G Clu clusterin JBrowse link 15 42,626,612 42,665,858 RGD:6480464
G Cnr1 cannabinoid receptor 1 JBrowse link 5 49,307,584 49,333,064 RGD:6480464
G Cnr2 cannabinoid receptor 2 JBrowse link 5 154,242,010 154,268,126 RGD:6480464
G Csf2 colony stimulating factor 2 JBrowse link 10 39,602,089 39,604,070 RGD:6480464
G Csf3 colony stimulating factor 3 JBrowse link 10 86,616,785 86,619,160 RGD:6480464
G Csrp2 cysteine and glycine-rich protein 2 JBrowse link 7 53,630,675 53,649,309 RGD:6480464
G Cthrc1 collagen triple helix repeat containing 1 JBrowse link 7 77,966,722 77,977,004 RGD:6480464
G Ctnnb1 catenin beta 1 JBrowse link 8 129,601,511 129,628,378 RGD:6480464
G Cxcl1 C-X-C motif chemokine ligand 1 JBrowse link 14 18,743,678 18,745,457 RGD:6480464
G Cxcl11 C-X-C motif chemokine ligand 11 JBrowse link 14 17,195,395 17,198,170 RGD:6480464
G Cxcl2 C-X-C motif chemokine ligand 2 JBrowse link 14 18,731,346 18,733,391 RGD:6480464
G Cxcl3 C-X-C motif chemokine ligand 3 JBrowse link 14 18,820,168 18,839,659 RGD:6480464
G Cxcr4 C-X-C motif chemokine receptor 4 JBrowse link 13 45,314,952 45,318,856 RGD:6480464
G Cyp24a1 cytochrome P450, family 24, subfamily a, polypeptide 1 JBrowse link 3 168,097,484 168,111,920 RGD:6480464
G Ddit4 DNA-damage-inducible transcript 4 JBrowse link 20 29,509,283 29,511,382 RGD:6480464
G Dhx9 DExH-box helicase 9 JBrowse link 13 70,885,503 70,922,278 RGD:6480464
G Dlg2 discs large MAGUK scaffold protein 2 JBrowse link 1 154,916,274 157,274,077 RGD:6480464
G Dnmt1 DNA methyltransferase 1 JBrowse link 8 21,922,515 21,968,495 RGD:6480464
G Dnmt3b DNA methyltransferase 3 beta JBrowse link 3 149,131,541 149,170,061 RGD:6480464
G Dpyd dihydropyrimidine dehydrogenase JBrowse link 2 221,823,692 222,694,627 RGD:6480464
G Dync1h1 dynein cytoplasmic 1 heavy chain 1 JBrowse link 6 134,958,854 135,085,769 RGD:6480464
G Edn1 endothelin 1 JBrowse link 17 22,136,814 22,143,745 RGD:6480464
G Edn2 endothelin 2 JBrowse link 5 139,098,472 139,106,396 RGD:6480464
G Egf epidermal growth factor JBrowse link 2 68,820,616 68,895,537 RGD:6480464
G Egfr epidermal growth factor receptor JBrowse link 14 99,919,485 100,104,136 RGD:6480464
G Egr1 early growth response 1 JBrowse link 18 27,657,903 27,660,101 RGD:6480464
G Esr1 estrogen receptor 1 JBrowse link 1 41,192,029 41,594,799 RGD:6480464
G Etv1 ETS variant transcription factor 1 JBrowse link 6 58,467,215 58,558,640 RGD:6480464
G Evi2b ecotropic viral integration site 2B JBrowse link 10 66,856,980 66,858,598 RGD:6480464
G F7 coagulation factor VII JBrowse link 16 81,824,610 81,834,923 RGD:6480464
G Fas Fas cell surface death receptor JBrowse link 1 252,589,785 252,624,790 RGD:6480464
G Fbxo25 F-box protein 25 JBrowse link 16 80,770,788 80,806,661 RGD:6480464
G Fgf2 fibroblast growth factor 2 JBrowse link 2 124,081,072 124,134,133 RGD:6480464
G Fgg fibrinogen gamma chain JBrowse link 2 181,987,080 181,994,523 RGD:6480464
G Fosl2 FOS like 2, AP-1 transcription factor subunit JBrowse link 6 25,598,936 25,616,995 RGD:6480464
G Fxyd3 FXYD domain-containing ion transport regulator 3 JBrowse link 1 89,502,561 89,510,146 RGD:6480464
G Gal3st1 galactose-3-O-sulfotransferase 1 JBrowse link 14 84,231,473 84,247,371 RGD:6480464
G Gas1 growth arrest-specific 1 JBrowse link 17 4,846,116 4,849,350 RGD:6480464
G Gask1b golgi associated kinase 1B JBrowse link 2 178,678,946 178,751,459 RGD:6480464
G Gdf15 growth differentiation factor 15 JBrowse link 16 20,555,395 20,557,978 RGD:6480464
G Gipc1 GIPC PDZ domain containing family, member 1 JBrowse link 19 24,786,604 24,798,231 RGD:6480464
G Gli2 GLI family zinc finger 2 JBrowse link 13 34,829,021 35,049,172 RGD:6480464
G Glrx glutaredoxin JBrowse link 2 2,606,032 2,615,944 RGD:6480464
G Gpc3 glypican 3 JBrowse link X 139,579,268 139,947,093 RGD:6480464
G Gsk3b glycogen synthase kinase 3 beta JBrowse link 11 65,060,884 65,208,842 RGD:6480464
G Gtf2a1 general transcription factor 2A subunit 1 JBrowse link 6 115,321,110 115,352,659 RGD:6480464
G Hdac9 histone deacetylase 9 JBrowse link 6 53,487,367 54,358,694 RGD:6480464
G Hif1a hypoxia inducible factor 1 subunit alpha JBrowse link 6 96,810,868 96,856,303 RGD:6480464
G Hist2h4 histone cluster 2, H4 JBrowse link 2 198,411,955 198,412,350 RGD:6480464
G Hoxb2 homeobox B2 JBrowse link 10 84,200,859 84,203,065 RGD:6480464
G Hspa1l heat shock protein family A (Hsp70) member 1 like JBrowse link 20 4,879,998 4,965,191 RGD:6480464
G Hspa5 heat shock protein family A (Hsp70) member 5 JBrowse link 3 13,838,304 13,842,763 RGD:6480464
G Icam1 intercellular adhesion molecule 1 JBrowse link 8 22,035,287 22,047,049 RGD:6480464
G Ifng interferon gamma JBrowse link 7 61,337,383 61,341,419 RGD:6480464
G Igf1r insulin-like growth factor 1 receptor JBrowse link 1 128,924,921 129,213,816 RGD:6480464
G Igfbp3 insulin-like growth factor binding protein 3 JBrowse link 14 87,457,647 87,465,374 RGD:6480464
G Il10 interleukin 10 JBrowse link 13 47,738,933 47,743,392 RGD:6480464
G Il13 interleukin 13 JBrowse link 10 38,982,909 38,985,466 RGD:6480464
G Il15 interleukin 15 JBrowse link 19 23,542,606 23,624,366 RGD:6480464
G Il16 interleukin 16 JBrowse link 1 145,781,923 145,881,538 RGD:6480464
G Il1a interleukin 1 alpha JBrowse link 3 121,824,712 121,836,122 RGD:6480464
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:6480464
G Il4 interleukin 4 JBrowse link 10 38,963,979 38,969,531 RGD:6480464
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:6480464
G Ilk integrin-linked kinase JBrowse link 1 170,578,941 170,585,192 RGD:6480464
G Ins2 insulin 2 JBrowse link 1 215,856,967 215,858,034 RGD:6480464
G Insig1 insulin induced gene 1 JBrowse link 4 342,302 350,515 RGD:6480464
G Iqgap1 IQ motif containing GTPase activating protein 1 JBrowse link 1 142,525,041 142,615,673 RGD:6480464
G Irak2 interleukin-1 receptor-associated kinase 2 JBrowse link 4 145,594,575 145,651,066 RGD:6480464
G Irf3 interferon regulatory factor 3 JBrowse link 1 100,992,244 100,997,202 RGD:6480464
G Itgav integrin subunit alpha V JBrowse link 3 71,113,269 71,205,958 RGD:6480464
G Itgb6 integrin subunit beta 6 JBrowse link 3 46,652,624 46,775,362 RGD:6480464
G Itsn2 intersectin 2 JBrowse link 6 30,098,378 30,208,694 RGD:6480464
G Jam3 junctional adhesion molecule 3 JBrowse link 8 28,147,110 28,208,466 RGD:6480464
G Jun Jun proto-oncogene, AP-1 transcription factor subunit JBrowse link 5 114,011,184 114,014,277 RGD:6480464
G Kctd12 potassium channel tetramerization domain containing 12 JBrowse link 15 87,384,632 87,390,627 RGD:6480464
G Kitlg KIT ligand JBrowse link 7 42,269,784 42,351,054 RGD:6480464
G Klf8 Kruppel-like factor 8 JBrowse link X 18,836,902 19,032,012 RGD:6480464
G Krt8 keratin 8 JBrowse link 7 143,596,511 143,603,745 RGD:6480464
G Larp4b La ribonucleoprotein 4B JBrowse link 17 63,236,007 63,317,298 RGD:6480464
G Lep leptin JBrowse link 4 56,337,695 56,351,818 RGD:6480464
G Lifr LIF receptor subunit alpha JBrowse link 2 56,424,910 56,489,346 RGD:6480464
G LOC100360841 ribosomal protein L37-like JBrowse link 9 69,790,829 69,791,199 RGD:6480464
G Lpar6 lysophosphatidic acid receptor 6 JBrowse link 15 55,126,953 55,128,762 RGD:6480464
G Lrrc28 leucine rich repeat containing 28 JBrowse link 1 128,486,164 128,604,190 RGD:6480464
G Lta lymphotoxin alpha JBrowse link 20 4,851,889 4,854,677 RGD:6480464
G Lyz2 lysozyme 2 JBrowse link 7 60,335,968 60,341,264 RGD:6480464
G Maf MAF bZIP transcription factor JBrowse link 19 48,179,826 48,200,995 RGD:6480464
G Magea10 MAGE family member A10 JBrowse link X 152,365,785 152,371,961 RGD:6480464
G Magi1 membrane associated guanylate kinase, WW and PDZ domain containing 1 JBrowse link 4 125,684,816 126,300,013 RGD:6480464
G Map2k3 mitogen activated protein kinase kinase 3 JBrowse link 10 45,089,455 45,110,802 RGD:6480464
G Map2k6 mitogen-activated protein kinase kinase 6 JBrowse link 10 98,707,160 98,823,054 RGD:6480464
G Mapk1 mitogen activated protein kinase 1 JBrowse link 11 88,203,863 88,273,301 RGD:6480464
G Mapk3 mitogen activated protein kinase 3 JBrowse link 1 198,192,773 198,198,975 RGD:6480464
G Marcks myristoylated alanine rich protein kinase C substrate JBrowse link 20 42,966,140 42,971,838 RGD:6480464
G Mars1 methionyl-tRNA synthetase 1 JBrowse link 7 70,585,011 70,602,425 RGD:6480464
G Mdm2 MDM2 proto-oncogene JBrowse link 7 60,719,060 60,743,618 RGD:6480464
G Mgmt O-6-methylguanine-DNA methyltransferase JBrowse link 1 209,237,255 209,464,189 RGD:6480464
G Mir24-2 microRNA 24-2 JBrowse link 19 25,318,863 25,318,970 RGD:6480464
G Mki67 marker of proliferation Ki-67 JBrowse link 1 207,993,895 208,020,454 RGD:6480464
G Mmp3 matrix metallopeptidase 3 JBrowse link 8 5,676,608 5,698,579 RGD:6480464
G Mmp9 matrix metallopeptidase 9 JBrowse link 3 161,413,410 161,421,473 RGD:6480464
G Mpo myeloperoxidase JBrowse link 10 75,087,892 75,098,260 RGD:6480464
G Msln mesothelin JBrowse link 10 15,119,700 15,129,129 RGD:6480464
G Mt-co3 mitochondrially encoded cytochrome c oxidase III JBrowse link MT 8,599 9,382 RGD:6480464
G Mxi1 MAX interactor 1, dimerization protein JBrowse link 1 274,030,748 274,090,071 RGD:6480464
G Myb MYB proto-oncogene, transcription factor JBrowse link 1 16,658,178 16,690,135 RGD:6480464
G Myc MYC proto-oncogene, bHLH transcription factor JBrowse link 7 102,586,313 102,591,240 RGD:6480464
G Nanog Nanog homeobox JBrowse link 4 155,531,906 155,539,268 RGD:6480464
G Ncbp1 nuclear cap binding protein subunit 1 JBrowse link 5 61,734,118 61,767,098 RGD:6480464
G Nedd9 neural precursor cell expressed, developmentally down-regulated 9 JBrowse link 17 22,984,792 23,179,701 RGD:6480464
G Neu1 neuraminidase 1 JBrowse link 20 4,610,995 4,615,258 RGD:6480464
G Nfe2l2 nuclear factor, erythroid 2-like 2 JBrowse link 3 62,497,568 62,525,146 RGD:6480464
G Nfkb2 nuclear factor kappa B subunit 2 JBrowse link 1 266,050,634 266,059,277 RGD:6480464
G Nfkbia NFKB inhibitor alpha JBrowse link 6 76,267,227 76,270,457 RGD:6480464
G Nfkbie NFKB inhibitor epsilon JBrowse link 9 17,828,405 17,835,240 RGD:6480464
G Nnmt nicotinamide N-methyltransferase JBrowse link 8 52,918,437 52,938,172 RGD:6480464
G Notch1 notch receptor 1 JBrowse link 3 3,905,562 3,951,015 RGD:6480464
G Npepps aminopeptidase puromycin sensitive JBrowse link 10 85,140,368 85,222,861 RGD:6480464
G Npm1 nucleophosmin 1 JBrowse link 10 18,080,949 18,091,062 RGD:6480464
G Nr4a3 nuclear receptor subfamily 4, group A, member 3 JBrowse link 5 63,781,801 63,822,890 RGD:6480464
G Nrg1 neuregulin 1 JBrowse link 16 62,969,573 64,065,063 RGD:6480464
G Nrp1 neuropilin 1 JBrowse link 19 61,332,351 61,486,166 RGD:6480464
G Nupr1 nuclear protein 1, transcriptional regulator JBrowse link 1 194,767,484 194,769,519 RGD:6480464
G Olr325 olfactory receptor 325 JBrowse link 1 228,545,913 228,546,857 RGD:6480464
G Osm oncostatin M JBrowse link 14 84,457,487 84,469,426 RGD:6480464
G Pappa1 pappalysin 1 JBrowse link 5 80,919,932 81,153,904 RGD:6480464
G Paqr8 progestin and adipoQ receptor family member 8 JBrowse link 9 27,005,270 27,054,591 RGD:6480464
G Parp1 poly (ADP-ribose) polymerase 1 JBrowse link 13 98,857,255 98,889,444 RGD:6480464
G Parp2 poly (ADP-ribose) polymerase 2 JBrowse link 15 27,739,416 27,749,650 RGD:6480464
G Pcsk9 proprotein convertase subtilisin/kexin type 9 JBrowse link 5 126,031,368 126,053,726 RGD:6480464
G Pdpk1 3-phosphoinositide dependent protein kinase-1 JBrowse link 10 13,446,373 13,525,248 RGD:6480464
G Pdzk1ip1 PDZK1 interacting protein 1 JBrowse link 5 133,895,849 133,900,720 RGD:6480464
G Pecam1 platelet and endothelial cell adhesion molecule 1 JBrowse link 10 94,850,971 94,913,202 RGD:6480464
G Pgr progesterone receptor JBrowse link 8 7,128,656 7,187,796 RGD:6480464
G Pja2 praja ring finger ubiquitin ligase 2 JBrowse link 9 111,998,204 112,048,847 RGD:6480464
G Plau plasminogen activator, urokinase JBrowse link 15 3,644,296 3,650,765 RGD:6480464
G Plk1 polo-like kinase 1 JBrowse link 1 192,115,990 192,125,969 RGD:6480464
G Ppara peroxisome proliferator activated receptor alpha JBrowse link 7 126,618,872 126,687,282 RGD:6480464
G Ppard peroxisome proliferator-activated receptor delta JBrowse link 20 7,818,289 7,883,482 RGD:6480464
G Pparg peroxisome proliferator-activated receptor gamma JBrowse link 4 147,274,055 147,399,383 RGD:6480464
G Ppfia4 PTPRF interacting protein alpha 4 JBrowse link 13 51,134,831 51,183,321 RGD:6480464
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A JBrowse link 1 101,511,899 101,515,043 RGD:6480464
G Psat1 phosphoserine aminotransferase 1 JBrowse link 1 233,124,089 233,145,941 RGD:6480464
G Ptch1 patched 1 JBrowse link 17 1,032,242 1,085,885 RGD:6480464
G Pten phosphatase and tensin homolog JBrowse link 1 251,421,814 251,487,634 RGD:6480464
G Ptgs1 prostaglandin-endoperoxide synthase 1 JBrowse link 3 15,560,685 15,582,339 RGD:6480464
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:6480464
G Ptk2 protein tyrosine kinase 2 JBrowse link 7 114,436,419 114,611,317 RGD:6480464
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 JBrowse link 12 40,895,515 40,955,999 RGD:6480464
G Rab8a RAB8A, member RAS oncogene family JBrowse link 16 19,355,047 19,376,776 RGD:6480464
G Rbm17 RNA binding motif protein 17 JBrowse link 17 70,586,345 70,603,289 RGD:6480464
G Reg3b regenerating family member 3 beta JBrowse link 4 109,467,272 109,470,510 RGD:6480464
G Rel REL proto-oncogene, NF-kB subunit JBrowse link 14 108,490,794 108,517,582 RGD:6480464
G Rela RELA proto-oncogene, NF-kB subunit JBrowse link 1 220,992,770 221,003,249 RGD:6480464
G Rgs2 regulator of G-protein signaling 2 JBrowse link 13 60,846,458 60,849,061 RGD:6480464
G Rnf149 ring finger protein 149 JBrowse link 9 46,285,546 46,309,692 RGD:6480464
G Rragd Ras-related GTP binding D JBrowse link 5 48,224,994 48,260,691 RGD:6480464
G Rrm1 ribonucleotide reductase catalytic subunit M1 JBrowse link 1 167,538,387 167,562,688 RGD:6480464
G Rrm2 ribonucleotide reductase regulatory subunit M2 JBrowse link 6 43,884,627 43,890,818 RGD:6480464
G Rsl24d1 ribosomal L24 domain containing 1 JBrowse link 8 79,792,587 79,801,592 RGD:6480464
G Sat1 spermidine/spermine N1-acetyl transferase 1 JBrowse link X 43,626,480 43,629,767 RGD:6480464
G Scd stearoyl-CoA desaturase JBrowse link 1 264,159,966 264,173,061 RGD:6480464
G Sfn stratifin JBrowse link 5 151,823,422 151,824,937 RGD:6480464
G Shh sonic hedgehog signaling molecule JBrowse link 4 718,538 727,691 RGD:6480464
G Slc25a29 solute carrier family 25 member 29 JBrowse link 6 132,736,964 132,747,912 RGD:6480464
G Slc28a1 solute carrier family 28 member 1 JBrowse link 1 142,948,942 142,992,410 RGD:6480464
G Slc29a1 solute carrier family 29 member 1 JBrowse link 9 17,784,468 17,799,008 RGD:6480464
G Slc29a3 solute carrier family 29 member 3 JBrowse link 20 30,289,527 30,327,343 RGD:6480464
G Slc2a3 solute carrier family 2 member 3 JBrowse link 4 155,549,991 155,626,018 RGD:6480464
G Slc43a3 solute carrier family 43, member 3 JBrowse link 3 72,328,912 72,351,039 RGD:6480464
G Slitrk2 SLIT and NTRK-like family, member 2 JBrowse link X 151,099,388 151,111,816 RGD:6480464
G Smg1 SMG1, nonsense mediated mRNA decay associated PI3K related kinase JBrowse link 1 187,781,577 187,882,833 RGD:6480464
G Smo smoothened, frizzled class receptor JBrowse link 4 57,019,941 57,041,779 RGD:6480464
G Sox2 SRY-box transcription factor 2 JBrowse link 2 121,165,137 121,167,545 RGD:6480464
G Spp1 secreted phosphoprotein 1 JBrowse link 14 6,673,686 6,679,965 RGD:6480464
G Src SRC proto-oncogene, non-receptor tyrosine kinase JBrowse link 3 153,547,807 153,595,643 RGD:6480464
G Stat3 signal transducer and activator of transcription 3 JBrowse link 10 88,790,401 88,842,263 RGD:6480464
G Syncrip synaptotagmin binding, cytoplasmic RNA interacting protein JBrowse link 8 96,100,692 96,266,342 RGD:6480464
G Szrd1 SUZ RNA binding domain containing 1 JBrowse link 5 159,638,259 159,662,790 RGD:6480464
G Tceal9 transcription elongation factor A like 9 JBrowse link X 106,791,333 106,794,667 RGD:6480464
G Tcof1 treacle ribosome biogenesis factor 1 JBrowse link 18 56,081,863 56,115,719 RGD:6480464
G Tert telomerase reverse transcriptase JBrowse link 1 32,250,876 32,275,330 RGD:6480464
G Tfap2a transcription factor AP-2 alpha JBrowse link 17 24,653,342 24,670,457 RGD:6480464
G Tgfb1 transforming growth factor, beta 1 JBrowse link 1 82,480,875 82,497,196 RGD:6480464
G Tgfb2 transforming growth factor, beta 2 JBrowse link 13 105,039,639 105,142,010 RGD:6480464
G Thpo thrombopoietin JBrowse link 11 82,845,676 82,853,439 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6480464
G Tnfaip3 TNF alpha induced protein 3 JBrowse link 1 14,401,103 14,416,369 RGD:6480464
G Tnfrsf11b TNF receptor superfamily member 11B JBrowse link 7 93,798,580 93,826,586 RGD:6480464
G Tnfsf10 TNF superfamily member 10 JBrowse link 2 113,008,008 113,026,899 RGD:6480464
G Tnfsf8 TNF superfamily member 8 JBrowse link 5 79,664,779 79,691,547 RGD:6480464
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:6480464
G Tp53bp1 tumor protein p53 binding protein 1 JBrowse link 3 113,160,030 113,259,701 RGD:6480464
G Tp53inp1 tumor protein p53 inducible nuclear protein 1 JBrowse link 5 24,402,895 24,419,651 RGD:6480464
G Traf1 TNF receptor-associated factor 1 JBrowse link 3 14,003,340 14,022,955 RGD:6480464
G Tube1 tubulin, epsilon 1 JBrowse link 20 44,220,823 44,238,830 RGD:6480464
G Tymp thymidine phosphorylase JBrowse link 7 130,342,481 130,347,845 RGD:6480464
G Tyrp1 tyrosinase-related protein 1 JBrowse link 5 98,387,291 98,406,083 RGD:6480464
G Ube2c ubiquitin-conjugating enzyme E2C JBrowse link 3 161,236,971 161,239,371 RGD:6480464
G Uggt2 UDP-glucose glycoprotein glucosyltransferase 2 JBrowse link 15 104,235,678 104,405,308 RGD:6480464
G Uhrf1 ubiquitin-like with PHD and ring finger domains 1 JBrowse link 9 10,738,211 10,758,403 RGD:6480464
G Vcam1 vascular cell adhesion molecule 1 JBrowse link 2 219,071,193 219,090,931 RGD:6480464
G Vegfa vascular endothelial growth factor A JBrowse link 9 17,340,341 17,355,681 RGD:6480464
G Vgf VGF nerve growth factor inducible JBrowse link 12 22,677,302 22,680,630 RGD:6480464
G Vldlr very low density lipoprotein receptor JBrowse link 1 245,236,819 245,273,688 RGD:6480464
G Vmp1 vacuole membrane protein 1 JBrowse link 10 73,901,988 74,001,900 RGD:6480464
G Vwf von Willebrand factor JBrowse link 4 158,085,059 158,219,525 RGD:6480464
G Wnt5a Wnt family member 5A JBrowse link 16 4,469,451 4,490,271 RGD:6480464
G Xbp1 X-box binding protein 1 JBrowse link 14 85,753,736 85,758,820 RGD:6480464
G Xiap X-linked inhibitor of apoptosis JBrowse link X 128,409,425 128,455,786 RGD:6480464
G Yap1 Yes1 associated transcriptional regulator JBrowse link 8 6,133,014 6,204,240 RGD:6480464
G Zfp110 zinc finger protein 110 JBrowse link 1 65,741,769 65,757,709 RGD:6480464
G Zfp449 zinc finger protein 449 JBrowse link X 73,390,885 73,413,939 RGD:6480464
G Zfp521 zinc finger protein 521 JBrowse link 18 5,022,042 5,315,242 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19758
    role 19705
      biological role 19704
        xenobiotic 18349
          gemcitabine 267
            gemcitabine hydrochloride 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19758
    subatomic particle 19756
      composite particle 19756
        hadron 19756
          baryon 19756
            nucleon 19756
              atomic nucleus 19756
                atom 19756
                  main group element atom 19641
                    p-block element atom 19641
                      carbon group element atom 19532
                        carbon atom 19521
                          organic molecular entity 19521
                            heteroorganic entity 19099
                              organochalcogen compound 18800
                                organooxygen compound 18713
                                  carbohydrates and carbohydrate derivatives 12122
                                    carbohydrate 12122
                                      carbohydrate derivative 11746
                                        glycosyl compound 10800
                                          N-glycosyl compound 5323
                                            nucleoside 5184
                                              deoxyribonucleoside 2706
                                                2'-deoxyribonucleoside 2188
                                                  pyrimidine 2'-deoxyribonucleoside 332
                                                    gemcitabine 267
                                                      gemcitabine hydrochloride 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.