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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:adefovir pivoxil
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Accession:CHEBI:31175 term browser browse the term
Definition:An organic phosphonate that is the dipivoxil ester of adefovir. A prodrug for adefovir, an HIV-1 reverse transcriptase inhibitor, adefovir pivoxil is used to treat chronic hepatitis B viral infection.
Synonyms:exact_synonym: ({[2-(6-amino-9H-purin-9-yl)ethoxy]methyl}phosphoryl)bis(oxymethanediyl) bis(2,2-dimethylpropanoate)
 related_synonym: (((2-(6-Amino-9H-purin-9-yl)ethoxy)methyl)phosphinylidene)bis(oxymethylene) 2,2-dimethylpropanoate;   9-(2-((Bis((pivaloyloxy)methoxy)phosphinyl)methoxy)ethyl)adenine;   Adefovir dipivoxil;   Formula=C20H32N5O8P;   GS 840;   GS-0840;   InChI=1S/C20H32N5O8P/c1-19(2,3)17(26)30-11-32-34(28,33-12-31-18(27)20(4,5)6)13-29-8-7-25-10-24-14-15(21)22-9-23-16(14)25/h9-10H,7-8,11-13H2,1-6H3,(H2,21,22,23);   InChIKey=WOZSCQDILHKSGG-UHFFFAOYSA-N;   SMILES=CC(C)(C)C(=O)OCOP(=O)(COCCN1C=NC2=C1N=CN=C2N)OCOC(=O)C(C)(C)C;   hepsera;   preveon
 xref: CAS:142340-99-6;   DrugBank:DB00718;   Drug_Central:88;   HMDB:HMDB0014856;   KEGG:D01655
 xref_mesh: MESH:C106812
 xref: PMID:10728465;   PMID:12099163;   PMID:25237370;   PMID:25493022;   PMID:25834334;   PMID:26082614;   PMID:26110616;   PMID:26427083;   PMID:26431662;   PMID:26447622;   PMID:26462447;   PMID:26885037;   PMID:26889227;   PMID:26908332;   PMID:27010143;   PMID:27079793;   PMID:27247753;   PMID:27301512;   PMID:27386642;   PMID:27664568;   PMID:27698751;   PMID:27877054;   PMID:27977591;   PMID:28123560;   PMID:30508954;   PMID:31919749;   PMID:32159854;   PMID:32406123;   Reaxys:29413415


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adefovir pivoxil term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor affects activity ISO adefovir dipivoxil affects the activity of AHR protein CTD PMID:25596134 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Ak4 adenylate kinase 4 increases expression ISO adefovir dipivoxil results in increased expression of AK4 mRNA CTD PMID:25596134 NCBI chr 5:116,039,222...116,099,064
Ensembl chr 5:116,039,616...116,098,618 		JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 decreases expression ISO adefovir dipivoxil results in decreased expression of AKR1C2 mRNA CTD PMID:25596134 NCBI chr17:65,759,778...65,808,013
Ensembl chr17:65,759,788...65,775,764 		JBrowse link
G Aldh18a1 aldehyde dehydrogenase 18 family, member A1 decreases expression ISO adefovir dipivoxil results in decreased expression of ALDH18A1 mRNA CTD PMID:25596134 NCBI chr 1:239,375,657...239,407,967
Ensembl chr 1:239,375,669...239,407,890 		JBrowse link
G Aldh1a3 aldehyde dehydrogenase 1 family, member A3 increases expression ISO adefovir dipivoxil results in increased expression of ALDH1A3 mRNA CTD PMID:25596134 NCBI chr 1:119,982,272...120,017,416
Ensembl chr 1:119,982,277...120,017,436 		JBrowse link
G Als2cl ALS2 C-terminal like increases expression ISO adefovir dipivoxil results in increased expression of ALS2CL mRNA CTD PMID:25596134 NCBI chr 8:110,863,753...110,884,434
Ensembl chr 8:110,864,975...110,884,419 		JBrowse link
G Angptl4 angiopoietin-like 4 increases expression ISO adefovir dipivoxil results in increased expression of ANGPTL4 mRNA CTD PMID:25596134 NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519 		JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) decreases expression ISO adefovir dipivoxil results in decreased expression of ASNS mRNA CTD PMID:25596134 NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423 		JBrowse link
G Atad2 ATPase family, AAA domain containing 2 increases expression ISO adefovir dipivoxil results in increased expression of ATAD2 mRNA CTD PMID:25596134 NCBI chr 7:89,634,123...89,676,738
Ensembl chr 7:89,634,123...89,676,738 		JBrowse link
G Atf3 activating transcription factor 3 increases expression ISO adefovir dipivoxil results in increased expression of ATF3 mRNA CTD PMID:25596134 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631 		JBrowse link
G Aurkb aurora kinase B increases expression ISO adefovir dipivoxil results in increased expression of AURKB mRNA CTD PMID:25596134 NCBI chr10:53,744,290...53,750,831
Ensembl chr10:53,745,142...53,750,837 		JBrowse link
G Axl Axl receptor tyrosine kinase increases expression ISO adefovir dipivoxil results in increased expression of AXL mRNA CTD PMID:25596134 NCBI chr 1:81,265,656...81,296,278
Ensembl chr 1:81,265,088...81,296,265 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO adefovir dipivoxil results in increased expression of BAX mRNA CTD PMID:25596134 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcar3 BCAR3 adaptor protein, NSP family member increases expression ISO adefovir dipivoxil results in increased expression of BCAR3 mRNA CTD PMID:25596134 NCBI chr 2:210,525,260...210,638,674
Ensembl chr 2:210,525,260...210,638,798 		JBrowse link
G Bend5 BEN domain containing 5 decreases expression ISO adefovir dipivoxil results in decreased expression of BEND5 mRNA CTD PMID:25596134 NCBI chr 5:126,290,648...126,336,662
Ensembl chr 5:125,254,956...126,534,367 		JBrowse link
G Bmf Bcl2 modifying factor decreases expression ISO adefovir dipivoxil results in decreased expression of BMF mRNA CTD PMID:25596134 NCBI chr 3:105,499,534...105,520,159
Ensembl chr 3:105,499,538...105,520,145 		JBrowse link
G Btg2 BTG anti-proliferation factor 2 increases expression ISO adefovir dipivoxil results in increased expression of BTG2 mRNA CTD PMID:25596134 NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628 		JBrowse link
G Ccne2 cyclin E2 increases expression ISO adefovir dipivoxil results in increased expression of CCNE2 mRNA CTD PMID:25596134 NCBI chr 5:24,285,078...24,298,258
Ensembl chr 5:24,284,922...24,297,632 		JBrowse link
G Cdk6 cyclin-dependent kinase 6 increases expression ISO adefovir dipivoxil results in increased expression of CDK6 mRNA CTD PMID:25596134 NCBI chr 4:30,637,650...30,829,688
Ensembl chr 4:30,646,460...30,829,634 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO adefovir dipivoxil results in increased expression of CDKN1A mRNA CTD PMID:25596134 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Cmbl carboxymethylenebutenolidase homolog increases expression ISO adefovir dipivoxil results in increased expression of CMBL mRNA CTD PMID:25596134 NCBI chr 2:82,569,257...82,591,007
Ensembl chr 2:82,571,888...82,591,009 		JBrowse link
G Coch cochlin increases expression ISO adefovir dipivoxil results in increased expression of COCH mRNA CTD PMID:25596134 NCBI chr 6:69,031,139...69,045,124
Ensembl chr 6:69,031,167...69,045,109 		JBrowse link
G Col4a1 collagen type IV alpha 1 chain decreases expression ISO adefovir dipivoxil results in decreased expression of COL4A1 mRNA CTD PMID:25596134 NCBI chr16:78,183,533...78,294,412
Ensembl chr16:78,183,533...78,294,412 		JBrowse link
G Cth cystathionine gamma-lyase decreases expression ISO adefovir dipivoxil results in decreased expression of CTH mRNA CTD PMID:25596134 NCBI chr 2:246,975,888...247,002,234
Ensembl chr 2:246,975,894...247,002,234 		JBrowse link
G Ctsc cathepsin C decreases expression ISO adefovir dipivoxil results in decreased expression of CTSC mRNA CTD PMID:25596134 NCBI chr 1:142,028,386...142,059,841
Ensembl chr 1:142,028,392...142,060,387 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 increases expression ISO adefovir dipivoxil results in increased expression of CYP1B1 mRNA CTD PMID:25596134 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 decreases activity ISO adefovir dipivoxil results in decreased activity of CYP3A4 protein CTD PMID:17162464 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Ddb2 damage specific DNA binding protein 2 increases expression ISO adefovir dipivoxil results in increased expression of DDB2 mRNA CTD PMID:25596134 NCBI chr 3:77,185,114...77,207,650
Ensembl chr 3:77,185,109...77,207,631 		JBrowse link
G Dgka diacylglycerol kinase, alpha increases expression ISO adefovir dipivoxil results in increased expression of DGKA mRNA CTD PMID:25596134 NCBI chr 7:1,148,734...1,175,324
Ensembl chr 7:1,148,735...1,175,110 		JBrowse link
G Dlgap5 DLG associated protein 5 increases expression ISO adefovir dipivoxil results in increased expression of DLGAP5 mRNA CTD PMID:25596134 NCBI chr15:20,633,964...20,664,569
Ensembl chr15:20,633,966...20,664,518 		JBrowse link
G Dlx1 distal-less homeobox 1 decreases expression ISO adefovir dipivoxil results in decreased expression of DLX1 mRNA CTD PMID:25596134 NCBI chr 3:56,356,190...56,360,780
Ensembl chr 3:56,356,190...56,360,780 		JBrowse link
G Dnai3 dynein axonemal intermediate chain 3 increases expression ISO adefovir dipivoxil results in increased expression of DNAI3 mRNA CTD PMID:25596134 NCBI chr 2:234,947,910...235,006,173
Ensembl chr 2:234,929,677...235,006,173 		JBrowse link
G Dpysl3 dihydropyrimidinase-like 3 increases expression ISO adefovir dipivoxil results in increased expression of DPYSL3 mRNA CTD PMID:25596134 NCBI chr18:35,374,429...35,480,462
Ensembl chr18:35,377,181...35,480,157 		JBrowse link
G Efna1 ephrin A1 decreases expression ISO adefovir dipivoxil results in decreased expression of EFNA1 mRNA CTD PMID:25596134 NCBI chr 2:174,681,676...174,690,306
Ensembl chr 2:174,681,682...174,690,866 		JBrowse link
G Ero1a endoplasmic reticulum oxidoreductase 1 alpha increases expression ISO adefovir dipivoxil results in increased expression of ERO1A mRNA CTD PMID:25596134 NCBI chr15:18,495,037...18,530,440
Ensembl chr15:18,492,945...18,530,478 		JBrowse link
G Fas Fas cell surface death receptor increases expression ISO adefovir dipivoxil results in increased expression of FAS mRNA CTD PMID:25596134 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Fbxo22 F-box protein 22 increases expression ISO adefovir dipivoxil results in increased expression of FBXO22 mRNA CTD PMID:25596134 NCBI chr 8:55,579,906...55,595,981
Ensembl chr 8:55,579,891...55,596,148 		JBrowse link
G Gabarapl1 GABA type A receptor associated protein like 1 decreases expression ISO adefovir dipivoxil results in decreased expression of GABARAPL1 mRNA CTD PMID:25596134 NCBI chr 4:162,980,309...162,989,452
Ensembl chr 4:162,980,249...162,989,450 		JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression ISO adefovir dipivoxil results in increased expression of GADD45A mRNA CTD PMID:25596134 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115 		JBrowse link
G Galnt16 polypeptide N-acetylgalactosaminyltransferase 16 decreases expression ISO adefovir dipivoxil results in decreased expression of GALNT16 mRNA CTD PMID:25596134 NCBI chr 6:100,168,943...100,250,718
Ensembl chr 6:100,170,306...100,250,705 		JBrowse link
G Gcnt3 glucosaminyl (N-acetyl) transferase 3, mucin type increases expression ISO adefovir dipivoxil results in increased expression of GCNT3 mRNA CTD PMID:25596134 NCBI chr 8:70,689,173...70,696,476
Ensembl chr 8:70,686,844...70,699,562 		JBrowse link
G Gdf15 growth differentiation factor 15 increases expression ISO adefovir dipivoxil results in increased expression of GDF15 mRNA CTD PMID:25596134 NCBI chr16:18,805,312...18,807,893
Ensembl chr16:18,805,239...18,808,055 		JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 decreases expression ISO adefovir dipivoxil results in decreased expression of GOT1 mRNA CTD PMID:25596134 NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633 		JBrowse link
G Gpr87 G protein-coupled receptor 87 increases expression ISO adefovir dipivoxil results in increased expression of GPR87 mRNA CTD PMID:25596134 NCBI chr 2:143,439,741...143,440,901
Ensembl chr 2:143,439,735...143,458,190 		JBrowse link
G H1f2 H1.2 linker histone, cluster member increases expression ISO adefovir dipivoxil results in increased expression of H1-2 mRNA CTD PMID:25596134 NCBI chr17:41,391,106...41,392,611 JBrowse link
G Hmox1 heme oxygenase 1 decreases expression ISO adefovir dipivoxil results in decreased expression of HMOX1 mRNA CTD PMID:25596134 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B decreases expression ISO adefovir dipivoxil results in decreased expression of HSPA1B mRNA CTD PMID:25596134 NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240 		JBrowse link
G Ifng interferon gamma multiple interactions ISO adefovir dipivoxil inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased activity of NOS2 protein]; adefovir dipivoxil inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of NOS2 mRNA]; adefovir dipivoxil inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of NOS2 protein] CTD PMID:9354585 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Il19 interleukin 19 increases secretion ISO adefovir dipivoxil results in increased secretion of IL19 protein CTD PMID:24714768 NCBI chr13:42,397,715...42,411,637
Ensembl chr13:42,399,138...42,405,473 		JBrowse link
G Kat6b lysine acetyltransferase 6B decreases expression ISO adefovir dipivoxil results in decreased expression of KAT6B mRNA CTD PMID:25596134 NCBI chr15:2,638,885...2,811,977
Ensembl chr15:2,639,200...2,812,316 		JBrowse link
G Kdm3a lysine demethylase 3A decreases expression ISO adefovir dipivoxil results in decreased expression of KDM3A mRNA CTD PMID:25596134 NCBI chr 4:103,630,907...103,675,073
Ensembl chr 4:103,630,908...103,675,073 		JBrowse link
G Krt15 keratin 15 increases expression ISO adefovir dipivoxil results in increased expression of KRT15 mRNA CTD PMID:25596134 NCBI chr10:85,066,797...85,070,614 JBrowse link
G Lama3 laminin subunit alpha 3 increases expression ISO adefovir dipivoxil results in increased expression of LAMA3 mRNA CTD PMID:25596134 NCBI chr18:3,523,168...3,751,722
Ensembl chr18:3,523,133...3,751,353 		JBrowse link
G Lcn2 lipocalin 2 increases secretion ISO adefovir dipivoxil results in increased secretion of LCN2 protein CTD PMID:24714768 NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095 		JBrowse link
G Map3k8 mitogen-activated protein kinase kinase kinase 8 increases expression ISO adefovir dipivoxil results in increased expression of MAP3K8 mRNA CTD PMID:25596134 NCBI chr17:53,382,908...53,403,216
Ensembl chr17:53,383,131...53,403,216 		JBrowse link
G Mdm2 MDM2 proto-oncogene increases expression ISO adefovir dipivoxil results in increased expression of MDM2 mRNA CTD PMID:25596134 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915 		JBrowse link
G Mxi1 MAX interactor 1, dimerization protein decreases expression ISO adefovir dipivoxil results in decreased expression of MXI1 mRNA CTD PMID:25596134 NCBI chr 1:252,323,915...252,383,682
Ensembl chr 1:252,323,303...252,383,681 		JBrowse link
G Ncapd2 non-SMC condensin I complex, subunit D2 increases expression ISO adefovir dipivoxil results in increased expression of NCAPD2 mRNA CTD PMID:25596134 NCBI chr 4:157,968,814...157,992,314
Ensembl chr 4:157,968,815...157,992,020 		JBrowse link
G Ninj1 ninjurin 1 increases expression ISO adefovir dipivoxil results in increased expression of NINJ1 mRNA CTD PMID:25596134 NCBI chr17:15,452,804...15,461,684
Ensembl chr17:15,452,813...15,461,704 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO adefovir dipivoxil inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased activity of NOS2 protein]; adefovir dipivoxil inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of NOS2 mRNA]; adefovir dipivoxil inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of NOS2 protein] CTD PMID:9354585 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 decreases expression ISO adefovir dipivoxil results in decreased expression of NQO1 mRNA CTD PMID:25596134 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G Nrep neuronal regeneration related protein decreases expression ISO adefovir dipivoxil results in decreased expression of NREP mRNA CTD PMID:25596134 NCBI chr18:25,017,069...25,046,564
Ensembl chr18:25,017,083...25,046,591 		JBrowse link
G Ntpcr nucleoside-triphosphatase, cancer-related increases expression ISO adefovir dipivoxil results in increased expression of NTPCR mRNA CTD PMID:25596134 NCBI chr19:53,701,496...53,715,260
Ensembl chr19:53,695,976...53,715,202 		JBrowse link
G P4ha1 prolyl 4-hydroxylase subunit alpha 1 decreases expression ISO adefovir dipivoxil results in decreased expression of P4HA1 mRNA CTD PMID:25596134 NCBI chr20:27,302,046...27,352,098
Ensembl chr20:27,302,141...27,352,786 		JBrowse link
G Pank1 pantothenate kinase 1 decreases expression ISO adefovir dipivoxil results in decreased expression of PANK1 mRNA CTD PMID:25596134 NCBI chr 1:232,324,718...232,395,445
Ensembl chr 1:232,328,430...232,396,829 		JBrowse link
G Pdia5 protein disulfide isomerase family A, member 5 increases expression ISO adefovir dipivoxil results in increased expression of PDIA5 mRNA CTD PMID:25596134 NCBI chr11:65,272,152...65,359,087
Ensembl chr11:65,272,155...65,359,084 		JBrowse link
G Pdlim1 PDZ and LIM domain 1 increases expression ISO adefovir dipivoxil results in increased expression of PDLIM1 mRNA CTD PMID:25596134 NCBI chr 1:239,042,372...239,091,074
Ensembl chr 1:239,042,385...239,091,076 		JBrowse link
G Pgr progesterone receptor multiple interactions ISO adefovir dipivoxil binds to and results in decreased activity of PGR protein CTD PMID:25752796 NCBI chr 8:6,073,216...6,131,552
Ensembl chr 8:6,072,673...6,131,344 		JBrowse link
G Phlda3 pleckstrin homology-like domain, family A, member 3 increases expression ISO adefovir dipivoxil results in increased expression of PHLDA3 mRNA CTD PMID:25596134 NCBI chr13:47,193,250...47,196,335
Ensembl chr13:47,193,086...47,196,335 		JBrowse link
G Pidd1 p53-induced death domain protein 1 increases expression ISO adefovir dipivoxil results in increased expression of PIDD1 mRNA CTD PMID:25596134 NCBI chr 1:196,536,815...196,542,808
Ensembl chr 1:196,536,834...196,542,699 		JBrowse link
G Pir pirin increases expression ISO adefovir dipivoxil results in increased expression of PIR mRNA CTD PMID:25596134 NCBI chr  X:30,108,536...30,219,269
Ensembl chr  X:30,108,538...30,219,218 		JBrowse link
G Plec plectin increases expression ISO adefovir dipivoxil results in increased expression of PLEC mRNA CTD PMID:25596134 NCBI chr 7:107,887,764...107,949,100
Ensembl chr 7:107,887,764...107,945,467 		JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 increases expression ISO adefovir dipivoxil results in increased expression of PMAIP1 mRNA CTD PMID:25596134 NCBI chr18:59,986,187...59,990,174
Ensembl chr18:59,986,017...59,992,429 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma affects activity ISO adefovir dipivoxil affects the activity of PPARG protein CTD PMID:25596134 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Ppm1d protein phosphatase, Mg2+/Mn2+ dependent, 1D increases expression ISO adefovir dipivoxil results in increased expression of PPM1D mRNA CTD PMID:25596134 NCBI chr10:70,172,603...70,208,607
Ensembl chr10:70,172,603...70,208,607 		JBrowse link
G Prc1 protein regulator of cytokinesis 1 increases expression ISO adefovir dipivoxil results in increased expression of PRC1 mRNA CTD PMID:25596134 NCBI chr 1:134,250,086...134,271,765
Ensembl chr 1:134,250,081...134,271,765 		JBrowse link
G Prdm1 PR/SET domain 1 increases expression ISO adefovir dipivoxil results in increased expression of PRDM1 mRNA CTD PMID:25596134 NCBI chr20:47,959,858...47,981,488
Ensembl chr20:47,959,858...47,981,488 		JBrowse link
G Prkab2 protein kinase AMP-activated non-catalytic subunit beta 2 decreases expression ISO adefovir dipivoxil results in decreased expression of PRKAB2 mRNA CTD PMID:25596134 NCBI chr 2:185,257,218...185,272,846
Ensembl chr 2:185,257,213...185,269,872 		JBrowse link
G Psat1 phosphoserine aminotransferase 1 decreases expression ISO adefovir dipivoxil results in decreased expression of PSAT1 mRNA CTD PMID:25596134 NCBI chr 1:213,196,709...213,218,564
Ensembl chr 1:213,196,709...213,218,682 		JBrowse link
G Rara retinoic acid receptor, alpha decreases expression ISO adefovir dipivoxil results in decreased expression of RARA mRNA CTD PMID:25596134 NCBI chr10:83,883,490...83,928,932
Ensembl chr10:83,893,384...83,928,142 		JBrowse link
G Rps27l ribosomal protein S27-like increases expression ISO adefovir dipivoxil results in increased expression of RPS27L mRNA CTD PMID:25596134 NCBI chr 8:67,562,483...67,567,418
Ensembl chr 8:67,562,483...67,567,418 		JBrowse link
G Rrm2b ribonucleotide reductase regulatory TP53 inducible subunit M2B increases expression ISO adefovir dipivoxil results in increased expression of RRM2B mRNA CTD PMID:25596134 NCBI chr 7:69,077,024...69,108,742
Ensembl chr 7:69,078,291...69,108,633 		JBrowse link
G Serpinb5 serpin family B member 5 increases expression ISO adefovir dipivoxil results in increased expression of SERPINB5 mRNA CTD PMID:25596134 NCBI chr13:22,985,557...23,005,756
Ensembl chr13:22,985,557...23,005,756 		JBrowse link
G Sesn1 sestrin 1 increases expression ISO adefovir dipivoxil results in increased expression of SESN1 mRNA CTD PMID:25596134 NCBI chr20:45,294,876...45,387,698
Ensembl chr20:45,294,871...45,387,697 		JBrowse link
G Sfn stratifin increases expression ISO adefovir dipivoxil results in increased expression of SFN mRNA CTD PMID:25596134 Ensembl chr 5:145,826,201...145,831,314 JBrowse link
G Sh3tc1 SH3 domain and tetratricopeptide repeats 1 decreases expression ISO adefovir dipivoxil results in decreased expression of SH3TC1 mRNA CTD PMID:25596134 NCBI chr14:75,005,691...75,050,001
Ensembl chr14:75,016,875...75,049,995 		JBrowse link
G Slc27a2 solute carrier family 27 member 2 decreases expression ISO adefovir dipivoxil results in decreased expression of SLC27A2 mRNA CTD PMID:25596134 NCBI chr 3:113,804,728...113,842,208
Ensembl chr 3:113,804,728...113,842,208 		JBrowse link
G Slc6a9 solute carrier family 6 member 9 decreases expression ISO adefovir dipivoxil results in decreased expression of SLC6A9 mRNA CTD PMID:25596134 NCBI chr 5:131,374,562...131,408,733
Ensembl chr 5:131,374,542...131,408,728 		JBrowse link
G Slco2b1 solute carrier organic anion transporter family, member 2b1 increases expression ISO adefovir dipivoxil results in increased expression of SLCO2B1 mRNA CTD PMID:25596134 NCBI chr 1:153,959,288...154,007,294
Ensembl chr 1:153,959,293...154,007,353 		JBrowse link
G Smap1 small ArfGAP 1 decreases expression ISO adefovir dipivoxil results in decreased expression of SMAP1 mRNA CTD PMID:25596134 NCBI chr 9:26,250,178...26,342,151
Ensembl chr 9:26,249,978...26,342,170 		JBrowse link
G Sulf2 sulfatase 2 increases expression ISO adefovir dipivoxil results in increased expression of SULF2 mRNA CTD PMID:25596134 NCBI chr 3:154,822,079...154,904,566
Ensembl chr 3:154,822,085...154,904,415 		JBrowse link
G Thra thyroid hormone receptor alpha multiple interactions ISO adefovir dipivoxil binds to and results in decreased activity of THRA protein CTD PMID:25752796 NCBI chr10:83,701,885...83,729,408
Ensembl chr10:83,700,755...83,729,936 		JBrowse link
G Tigar TP53 induced glycolysis regulatory phosphatase increases expression ISO adefovir dipivoxil results in increased expression of TIGAR mRNA CTD PMID:25596134 NCBI chr 4:159,927,138...159,946,094
Ensembl chr 4:159,927,139...159,946,029 		JBrowse link
G Tiparp TCDD-inducible poly(ADP-ribose) polymerase increases expression ISO adefovir dipivoxil results in increased expression of TIPARP mRNA CTD PMID:25596134 NCBI chr 2:149,753,682...149,780,327
Ensembl chr 2:149,753,682...149,780,327 		JBrowse link
G Tnfsf9 TNF superfamily member 9 increases expression ISO adefovir dipivoxil results in increased expression of TNFSF9 mRNA CTD PMID:25596134 NCBI chr 9:1,944,017...1,946,351
Ensembl chr 9:1,944,017...1,946,345 		JBrowse link
G Tp53 tumor protein p53 affects activity ISO adefovir dipivoxil affects the activity of TP53 protein CTD PMID:25596134 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Tp53inp1 tumor protein p53 inducible nuclear protein 1 increases expression ISO adefovir dipivoxil results in increased expression of TP53INP1 mRNA CTD PMID:25596134 NCBI chr 5:24,253,986...24,272,250
Ensembl chr 5:24,260,568...24,267,968 		JBrowse link
G Trafd1 TRAF type zinc finger domain containing 1 decreases expression ISO adefovir dipivoxil results in decreased expression of TRAFD1 mRNA CTD PMID:25596134 NCBI chr12:35,165,606...35,179,525
Ensembl chr12:35,165,606...35,179,525 		JBrowse link
G Triap1 TP53 regulated inhibitor of apoptosis 1 increases expression ISO adefovir dipivoxil results in increased expression of TRIAP1 mRNA CTD PMID:25596134 NCBI chr12:41,267,534...41,270,053
Ensembl chr12:41,267,549...41,270,042 		JBrowse link
G Ube2o ubiquitin-conjugating enzyme E2O decreases expression ISO adefovir dipivoxil results in decreased expression of UBE2O mRNA CTD PMID:25596134 NCBI chr10:101,765,572...101,812,736
Ensembl chr10:101,766,005...101,812,899 		JBrowse link
G Yars1 tyrosyl-tRNA synthetase 1 decreases expression ISO adefovir dipivoxil results in decreased expression of YARS1 mRNA CTD PMID:25596134 NCBI chr 5:141,535,815...141,564,029
Ensembl chr 5:141,535,759...141,563,833 		JBrowse link
G Zmat3 zinc finger, matrin type 3 increases expression ISO adefovir dipivoxil results in increased expression of ZMAT3 mRNA CTD PMID:25596134 NCBI chr 2:115,106,050...115,136,863
Ensembl chr 2:115,106,966...115,136,863 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19800
    role 19751
      application 19498
        pro-agent 10115
          prodrug 9918
            adefovir pivoxil 102
Path 2
Term Annotations click to browse term
  CHEBI ontology 19800
    subatomic particle 19799
      composite particle 19799
        hadron 19799
          baryon 19799
            nucleon 19799
              atomic nucleus 19799
                atom 19799
                  main group element atom 19698
                    p-block element atom 19698
                      carbon group element atom 19619
                        carbon atom 19609
                          organic molecular entity 19609
                            organic molecule 19549
                              organic cyclic compound 19343
                                organic heterocyclic compound 18584
                                  organic heteropolycyclic compound 18043
                                    organic heterobicyclic compound 16859
                                      imidazopyrimidine 5618
                                        purines 5616
                                          aminopurine 4434
                                            6-aminopurines 809
                                              adenine 802
                                                adefovir 111
                                                  adefovir pivoxil 102
paths to the root