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ONTOLOGY REPORT - ANNOTATIONS


Term:ketanserin
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Accession:CHEBI:6123 term browser browse the term
Definition:A member of the class of quinazolines that is quinazoline-2,4(1H,3H)-dione which is substituted at position 3 by a 2-[4-(p-fluorobenzoyl)piperidin-1-yl]ethyl group.
Synonyms:exact_synonym: 3-{2-[4-(4-fluorobenzoyl)piperidin-1-yl]ethyl}quinazoline-2,4(1H,3H)-dione
 related_synonym: 3-[2-[4-(4-fluorobenzoyl)-1-piperidyl]ethyl]-1H-quinazoline-2,4-dione;   Formula=C22H22FN3O3;   InChI=1S/C22H22FN3O3/c23-17-7-5-15(6-8-17)20(27)16-9-11-25(12-10-16)13-14-26-21(28)18-3-1-2-4-19(18)24-22(26)29/h1-8,16H,9-14H2,(H,24,29);   InChIKey=FPCCSQOGAWCVBH-UHFFFAOYSA-N;   SMILES=Fc1ccc(cc1)C(=O)C1CCN(CC1)CCn1c(=O)[nH]c2ccccc2c1=O;   ketanserina;   ketanserine;   ketanserinum
 xref: Beilstein:4913068;   CAS:74050-98-9;   Drug_Central:1524;   KEGG:C07464;   KEGG:D02363;   LINCS:LSM-3092
 xref_mesh: MESH:D007650
 xref: PMID:11110040;   PMID:18574455;   PMID:18950618;   PMID:19058975;   PMID:20825390;   PMID:22091605;   PMID:2678304;   PMID:8583787;   Patent:EP13612;   Patent:US4335127;   Reaxys:4913068;   Wikipedia:Ketanserin


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ketanserin term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adra1a adrenoceptor alpha 1A JBrowse link 15 43,296,997 43,398,314 RGD:6480464
G Adra1b adrenoceptor alpha 1B JBrowse link 10 29,392,762 29,450,644 RGD:6480464
G Adra1d adrenoceptor alpha 1D JBrowse link 3 124,129,558 124,145,566 RGD:6480464
G Akt1 AKT serine/threonine kinase 1 JBrowse link 6 137,218,398 137,239,970 RGD:6480464
G Bdnf brain-derived neurotrophic factor JBrowse link 3 100,768,637 100,819,216 RGD:6480464
G Ctnnb1 catenin beta 1 JBrowse link 8 129,601,511 129,628,378 RGD:6480464
G Ddc dopa decarboxylase JBrowse link 14 91,905,919 91,996,816 RGD:6480464
G Htr2a 5-hydroxytryptamine receptor 2A JBrowse link 15 56,666,152 56,732,469 RGD:6480464
G Htr7 5-hydroxytryptamine receptor 7 JBrowse link 1 254,547,964 254,671,811 RGD:6480464
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:6480464
G Irs1 insulin receptor substrate 1 JBrowse link 9 88,033,668 88,086,488 RGD:6480464
G Mapk1 mitogen activated protein kinase 1 JBrowse link 11 88,203,863 88,273,301 RGD:6480464
G Mapk3 mitogen activated protein kinase 3 JBrowse link 1 198,192,773 198,198,975 RGD:6480464
G Nfe2l2 nuclear factor, erythroid 2-like 2 JBrowse link 3 62,497,568 62,525,146 RGD:6480464
G Ppp1r1b protein phosphatase 1, regulatory (inhibitor) subunit 1B JBrowse link 10 86,303,727 86,312,770 RGD:6480464
G Slc6a4 solute carrier family 6 member 4 JBrowse link 10 63,153,656 63,188,377 RGD:6480464
G Ywhab tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta JBrowse link 3 160,391,108 160,399,931 RGD:6480464

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Term Annotations click to browse term
  CHEBI ontology 19758
    role 19705
      application 19359
        pharmaceutical 19228
          drug 19228
            cardiovascular drug 7592
              ketanserin 17
Path 2
Term Annotations click to browse term
  CHEBI ontology 19758
    subatomic particle 19756
      composite particle 19756
        hadron 19756
          baryon 19756
            nucleon 19756
              atomic nucleus 19756
                atom 19756
                  main group element atom 19641
                    p-block element atom 19641
                      carbon group element atom 19532
                        carbon atom 19521
                          organic molecular entity 19521
                            organic group 18428
                              organic divalent group 18419
                                organodiyl group 18419
                                  carbonyl group 18309
                                    carbonyl compound 18309
                                      ketone 15948
                                        aromatic ketone 11839
                                          ketanserin 17
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