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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:morin
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Accession:CHEBI:75092 term browser browse the term
Definition:A pentahydroxyflavone that is 7-hydroxyflavonol bearing three additional hydroxy substituents at positions 2' 4' and 5.
Synonyms:exact_synonym: 2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chromen-4-one
 related_synonym: 2',4',3,5,7-Pentahydroxyflavone;   2',4',5,7-Tetrahydroxyflavan-3-ol;   2',4',5,7-Tetrahydroxyflavonol;   2-(2,4-Dihydroxyphenyl)-3,5,7-trihydroxy-4H-1-benzopyran-4-one;   C.I.Natural Yellow 8;   Formula=C15H10O7;   InChI=1S/C15H10O7/c16-6-1-2-8(9(18)3-6)15-14(21)13(20)12-10(19)4-7(17)5-11(12)22-15/h1-5,16-19,21H;   InChIKey=YXOLAZRVSSWPPT-UHFFFAOYSA-N;   SMILES=Oc1ccc(c(O)c1)-c1oc2cc(O)cc(O)c2c(=O)c1O
 alt_id: CHEBI:6998
 xref: CAS:480-16-0;   HMDB:HMDB0030796;   KEGG:C10105;   KNApSAcK:C00004624;   LINCS:LSM-36988;   LIPID_MAPS_instance:LMPK12112517
 xref_mesh: MESH:C008548
 xref: PMID:15516722;   PMID:16806951;   PMID:18629640;   PMID:19539802;   PMID:19774509;   PMID:22740350;   PMID:23030699;   PMID:23254912;   PMID:23279849;   PMID:23352912;   PMID:23384060;   PMID:23432089;   PMID:23590821;   PMID:23757948;   PMID:23952478;   Reaxys:327474;   Wikipedia:Morin_(flavonol)



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morin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 decreases activity
multiple interactions
ISO morin results in decreased activity of ABCB11 protein
morin inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid]
CTD PMID:24014644 NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A increases activity
multiple interactions
ISO morin results in increased activity of ABCB1 protein
morin promotes the reaction [Quercetin results in increased activity of ABCB1 protein]
CTD PMID:34217736 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 decreases activity ISO morin results in decreased activity of ABCC1 protein CTD PMID:15670588 NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
JBrowse link
G Ache acetylcholinesterase multiple interactions EXP morin inhibits the reaction [Ifosfamide results in increased activity of ACHE protein] CTD PMID:31722249 NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651
JBrowse link
G Acta2 actin alpha 2, smooth muscle multiple interactions EXP morin inhibits the reaction [Dimethylnitrosamine results in increased expression of ACTA2 mRNA]; morin inhibits the reaction [Dimethylnitrosamine results in increased expression of ACTA2 protein] CTD PMID:18629640 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing multiple interactions EXP morin analog inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of ADIPOQ protein] CTD PMID:24854284 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions ISO AHR gene mutant form inhibits the reaction [morin results in increased expression of CYP1A1 mRNA]; AHR gene mutant form inhibits the reaction [morin results in increased expression of UGT1A1 mRNA] CTD PMID:29584932 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 multiple interactions EXP morin inhibits the reaction [Excitatory Amino Acid Agonists affects the localization of AIFM1 protein] CTD PMID:19201465 NCBI chr  X:127,650,223...127,689,356
Ensembl chr  X:127,650,226...127,689,256
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions
increases expression
EXP
ISO
morin inhibits the reaction [Acetaminophen results in decreased phosphorylation of AKT1 protein]; morin inhibits the reaction [Excitatory Amino Acid Agonists results in decreased phosphorylation of AKT1 protein]; morin inhibits the reaction [Streptozocin results in increased expression of AKT1 mRNA]
morin results in increased expression of AKT1 mRNA
CTD PMID:19201465 PMID:26767949 PMID:28689916 PMID:35414346 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 increases expression ISO morin results in increased expression of APAF1 mRNA CTD PMID:28689916 NCBI chr 7:25,494,143...25,579,540
Ensembl chr 7:25,494,609...25,579,540
JBrowse link
G App amyloid beta precursor protein multiple interactions ISO morin affects the reaction [APP protein binds to APP protein] CTD PMID:18537544 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
JBrowse link
G Aqp2 aquaporin 2 multiple interactions EXP morin inhibits the reaction [Doxorubicin affects the expression of AQP2 protein] CTD PMID:31100273 NCBI chr 7:130,711,433...130,716,468
Ensembl chr 7:130,711,413...130,716,468
JBrowse link
G Ar androgen receptor decreases expression ISO morin results in decreased expression of AR mRNA CTD PMID:24726691 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions
increases expression
EXP
ISO
morin inhibits the reaction [Acetaminophen results in increased expression of BAX protein]; morin inhibits the reaction [Diethylnitrosamine results in decreased expression of BAX protein]; morin inhibits the reaction [Doxorubicin affects the expression of BAX protein]; morin inhibits the reaction [Excitatory Amino Acid Agonists results in increased expression of BAX protein]; morin inhibits the reaction [Streptozocin results in increased expression of BAX mRNA]; morin inhibits the reaction [titanium dioxide results in increased expression of BAX mRNA]
morin results in increased expression of BAX mRNA
CTD PMID:19201465 PMID:19931519 PMID:26767949 PMID:28689916 PMID:28844848 More... NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bche butyrylcholinesterase multiple interactions EXP morin inhibits the reaction [Ifosfamide results in increased activity of BCHE protein] CTD PMID:31722249 NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
decreases expression
EXP
ISO
morin inhibits the reaction [Acetaminophen results in decreased expression of BCL2 protein]; morin inhibits the reaction [Diethylnitrosamine results in increased expression of BCL2 protein]; morin inhibits the reaction [Doxorubicin results in decreased expression of BCL2 protein]; morin inhibits the reaction [Ifosfamide results in decreased expression of BCL2 mRNA]; morin inhibits the reaction [Streptozocin results in increased expression of BCL2 mRNA]; morin inhibits the reaction [titanium dioxide results in decreased expression of BCL2 mRNA]
morin results in decreased expression of BCL2 mRNA
CTD PMID:19931519 PMID:26767949 PMID:28689916 PMID:28844848 PMID:31100273 More... NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Bcl2l1 Bcl2-like 1 decreases expression
multiple interactions
ISO
EXP
morin results in decreased expression of BCL2L1 mRNA
morin inhibits the reaction [Streptozocin results in increased expression of BCL2L1 mRNA]
CTD PMID:28689916 PMID:35414346 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Bdnf brain-derived neurotrophic factor multiple interactions EXP morin inhibits the reaction [Ifosfamide results in increased expression of BDNF mRNA]; morin inhibits the reaction [Streptozocin results in increased expression of BDNF mRNA] CTD PMID:31722249 PMID:35414346 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
JBrowse link
G Birc2 baculoviral IAP repeat-containing 2 decreases expression ISO morin results in decreased expression of BIRC2 mRNA CTD PMID:28689916 NCBI chr 8:4,968,856...4,989,325
Ensembl chr 8:4,968,842...4,988,732
JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 decreases expression ISO morin results in decreased expression of BIRC3 mRNA CTD PMID:28689916 NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 decreases expression ISO morin results in decreased expression of BIRC5 mRNA CTD PMID:28689916 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity
EXP
ISO
morin inhibits the reaction [Acetaminophen results in increased activity of CASP3 protein]; morin inhibits the reaction [Acetaminophen results in increased cleavage of CASP3 protein]; morin inhibits the reaction [Diethylnitrosamine results in decreased expression of CASP3 protein]; morin inhibits the reaction [Ifosfamide results in increased activity of CASP3 protein]; morin inhibits the reaction [Streptozocin results in increased expression of CASP3 mRNA]; morin inhibits the reaction [titanium dioxide results in increased expression of CASP3 mRNA]
morin results in increased activity of CASP3 protein
CTD PMID:19931519 PMID:24726691 PMID:26767949 PMID:28844848 PMID:31722249 More... NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp7 caspase 7 increases activity ISO morin results in increased activity of CASP7 protein CTD PMID:24726691 NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729
JBrowse link
G Casp9 caspase 9 multiple interactions EXP morin inhibits the reaction [Acetaminophen results in increased activity of CASP9 protein]; morin inhibits the reaction [Diethylnitrosamine results in decreased expression of CASP9 protein] CTD PMID:19931519 PMID:26767949 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cat catalase multiple interactions EXP Indomethacin promotes the reaction [morin inhibits the reaction [Freund's Adjuvant results in decreased activity of CAT protein]]; morin analog inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased activity of CAT protein]; morin inhibits the reaction [Acetaminophen results in decreased activity of CAT protein]; morin inhibits the reaction [Doxorubicin results in decreased activity of CAT protein]; morin inhibits the reaction [Excitatory Amino Acid Agonists results in decreased activity of CAT protein]; morin inhibits the reaction [Freund's Adjuvant results in decreased activity of CAT protein]; morin inhibits the reaction [Ifosfamide results in decreased activity of CAT protein]; morin inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; morin promotes the reaction [Indomethacin inhibits the reaction [Freund's Adjuvant results in decreased activity of CAT protein]] CTD PMID:19201465 PMID:24854284 PMID:25698669 PMID:26767949 PMID:31100273 More... NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions EXP [morin co-treated with Indomethacin] inhibits the reaction [Freund's Adjuvant results in increased expression of CCL2 mRNA]; Indomethacin promotes the reaction [morin inhibits the reaction [Freund's Adjuvant results in increased expression of CCL2 protein]]; morin inhibits the reaction [Freund's Adjuvant results in increased expression of CCL2 mRNA]; morin inhibits the reaction [Freund's Adjuvant results in increased expression of CCL2 protein]; morin promotes the reaction [Indomethacin inhibits the reaction [Freund's Adjuvant results in increased expression of CCL2 protein]] CTD PMID:25698669 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccnb1 cyclin B1 decreases expression ISO morin results in decreased expression of CCNB1 mRNA CTD PMID:28689916 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
JBrowse link
G Cdc25c cell division cycle 25C decreases expression ISO morin results in decreased expression of CDC25C mRNA CTD PMID:28689916 NCBI chr18:26,335,156...26,356,199
Ensembl chr18:26,335,834...26,356,185
JBrowse link
G Cdk1 cyclin-dependent kinase 1 decreases expression ISO morin results in decreased expression of CDK1 mRNA CTD PMID:28689916 NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO morin results in increased expression of CDKN1A mRNA CTD PMID:28689916 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Chek2 checkpoint kinase 2 decreases expression ISO morin results in decreased expression of CHEK2 mRNA CTD PMID:28689916 NCBI chr12:45,788,823...45,821,382
Ensembl chr12:45,788,827...45,821,286
JBrowse link
G Col2a1 collagen type II alpha 1 chain multiple interactions ISO 2-chloro-5-nitrobenzanilide inhibits the reaction [morin inhibits the reaction [COL2A1 protein results in increased expression of FASN mRNA]]; morin inhibits the reaction [COL2A1 protein results in increased expression of FASN mRNA] CTD PMID:36121554 NCBI chr 7:129,098,489...129,127,560
Ensembl chr 7:129,098,786...129,127,546
JBrowse link
G Cp ceruloplasmin multiple interactions EXP [Indomethacin co-treated with morin] inhibits the reaction [Freund's Adjuvant results in increased expression of CP protein]; morin inhibits the reaction [Freund's Adjuvant results in increased expression of CP protein] CTD PMID:25698669 NCBI chr 2:102,439,433...102,498,075
Ensembl chr 2:102,439,624...102,498,075
JBrowse link
G Ctsd cathepsin D multiple interactions EXP [morin co-treated with Indomethacin] inhibits the reaction [Freund's Adjuvant results in increased activity of CTSD protein]; morin inhibits the reaction [Freund's Adjuvant results in increased activity of CTSD protein] CTD PMID:25698669 NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488
JBrowse link
G Cycs cytochrome c, somatic multiple interactions EXP morin inhibits the reaction [Diethylnitrosamine results in decreased expression of CYCS protein]; morin inhibits the reaction [Streptozocin results in increased expression of CYCS mRNA] CTD PMID:19931519 PMID:35414346 NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
Ensembl chr18:79,651,378...79,654,054
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
increases expression
ISO morin affects the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]
AHR gene mutant form inhibits the reaction [morin results in increased expression of CYP1A1 mRNA]
morin results in increased expression of CYP1A1 mRNA; morin results in increased expression of CYP1A1 protein
CTD PMID:20930378 PMID:29584932 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Diablo diablo, IAP-binding mitochondrial protein increases expression ISO morin results in increased expression of DIABLO mRNA CTD PMID:28689916 NCBI chr12:33,055,784...33,070,401
Ensembl chr12:33,055,263...33,070,387
JBrowse link
G Dio1 iodothyronine deiodinase 1 decreases activity ISO morin results in decreased activity of DIO1 protein CTD PMID:30561685 NCBI chr 5:122,074,285...122,090,983
Ensembl chr 5:122,074,279...122,090,970
JBrowse link
G Dio3 iodothyronine deiodinase 3 decreases activity ISO morin results in decreased activity of DIO3 protein CTD PMID:30561685 NCBI chr 6:129,285,747...129,287,608
Ensembl chr 6:129,285,749...129,286,660
JBrowse link
G Eif2a eukaryotic translation initiation factor 2A multiple interactions EXP [morin co-treated with 1,2-Dimethylhydrazine] results in increased phosphorylation of EIF2A protein CTD PMID:32028820 NCBI chr 2:142,761,303...142,794,767
Ensembl chr 2:142,761,416...142,795,068
JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 multiple interactions
increases phosphorylation
EXP [1,2-Dimethylhydrazine co-treated with morin] results in increased expression of EIF2AK3 protein
morin results in increased phosphorylation of EIF2AK3 protein
CTD PMID:32028820 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911
JBrowse link
G Fadd Fas associated via death domain increases expression ISO morin results in increased expression of FADD mRNA CTD PMID:28689916 NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653
JBrowse link
G Fas Fas cell surface death receptor multiple interactions EXP morin inhibits the reaction [titanium dioxide results in increased expression of FAS mRNA] CTD PMID:28844848 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Faslg Fas ligand increases expression ISO morin results in increased expression of FASLG mRNA CTD PMID:28689916 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215
JBrowse link
G Fasn fatty acid synthase multiple interactions ISO 2-chloro-5-nitrobenzanilide inhibits the reaction [morin inhibits the reaction [COL2A1 protein results in increased expression of FASN mRNA]]; morin inhibits the reaction [COL2A1 protein results in increased expression of FASN mRNA] CTD PMID:36121554 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP morin inhibits the reaction [Ifosfamide results in increased expression of FOS protein] CTD PMID:31722249 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Fshb follicle stimulating hormone subunit beta multiple interactions EXP morin inhibits the reaction [titanium dioxide results in increased expression of FSHB protein] CTD PMID:28844848 NCBI chr 3:93,548,560...93,552,370
Ensembl chr 3:93,548,560...93,552,370
JBrowse link
G Gfap glial fibrillary acidic protein multiple interactions EXP morin inhibits the reaction [Ifosfamide results in increased expression of GFAP protein] CTD PMID:31722249 NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions EXP morin analog inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased activity of GPT protein]; morin inhibits the reaction [Doxorubicin results in increased activity of GPT protein] CTD PMID:24854284 PMID:31100273 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
JBrowse link
G Gpx2 glutathione peroxidase 2 multiple interactions EXP [1,2-Dimethylhydrazine co-treated with morin] results in increased expression of GPX2 mRNA CTD PMID:32028820 NCBI chr 6:95,493,589...95,496,877
Ensembl chr 6:95,493,589...95,496,877
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions EXP morin inhibits the reaction [Acetaminophen results in decreased phosphorylation of GSK3B protein]; morin inhibits the reaction [Diethylnitrosamine results in increased expression of GSK3B protein modified form] CTD PMID:19931519 PMID:26767949 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions EXP morin inhibits the reaction [Streptozocin results in decreased activity of GSR protein] CTD PMID:35414346 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions EXP [1,2-Dimethylhydrazine co-treated with morin] results in increased expression of HMOX1 mRNA; morin inhibits the reaction [Acetaminophen results in decreased expression of HMOX1 protein] CTD PMID:26767949 PMID:32028820 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Ifng interferon gamma multiple interactions ISO morin inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased abundance of Nitric Oxide] CTD PMID:22698256 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Il17a interleukin 17A multiple interactions EXP [morin co-treated with Indomethacin] inhibits the reaction [Freund's Adjuvant results in increased expression of IL17A mRNA]; morin inhibits the reaction [Freund's Adjuvant results in increased expression of IL17A mRNA] CTD PMID:25698669 NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO
EXP
morin inhibits the reaction [[Lipopolysaccharides co-treated with Thioglycolates] results in increased expression of IL1B mRNA]; morin inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]
[morin co-treated with Indomethacin] inhibits the reaction [Freund's Adjuvant results in increased expression of IL1B mRNA]; Indomethacin promotes the reaction [morin inhibits the reaction [Freund's Adjuvant results in increased expression of IL1B protein]]; morin inhibits the reaction [Doxorubicin results in increased expression of IL1B protein]; morin inhibits the reaction [Freund's Adjuvant results in increased expression of IL1B mRNA]; morin inhibits the reaction [Freund's Adjuvant results in increased expression of IL1B protein]; morin promotes the reaction [Indomethacin inhibits the reaction [Freund's Adjuvant results in increased expression of IL1B protein]]
CTD PMID:22698256 PMID:25698669 PMID:31100273 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il6 interleukin 6 multiple interactions ISO
EXP
morin inhibits the reaction [[Lipopolysaccharides co-treated with Thioglycolates] results in increased expression of IL6 mRNA]; morin inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]
[morin co-treated with Indomethacin] inhibits the reaction [Freund's Adjuvant results in increased expression of IL6 mRNA]; morin inhibits the reaction [Freund's Adjuvant results in increased expression of IL6 mRNA]
CTD PMID:22698256 PMID:25698669 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Ins1 insulin 1 multiple interactions EXP morin analog inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of INS1 protein]; morin inhibits the reaction [Streptozocin results in decreased expression of INS1 protein] CTD PMID:24854284 PMID:35414346 NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536
JBrowse link
G Iyd iodotyrosine deiodinase multiple interactions ISO morin inhibits the reaction [IYD protein results in increased metabolism of Monoiodotyrosine] CTD PMID:33352258 NCBI chr 1:40,003,999...40,019,323
Ensembl chr 1:40,004,041...40,019,319
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP [morin co-treated with Indomethacin] inhibits the reaction [Freund's Adjuvant results in increased expression of JUN mRNA]; morin inhibits the reaction [Freund's Adjuvant results in increased expression of JUN mRNA] CTD PMID:25698669 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase multiple interactions EXP morin inhibits the reaction [titanium dioxide results in decreased expression of KIT mRNA] CTD PMID:28844848 NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652
JBrowse link
G Krt1 keratin 1 multiple interactions ISO morin inhibits the reaction [Calcium results in increased expression of KRT1 mRNA] CTD PMID:12069687 NCBI chr 7:132,976,618...132,981,844
Ensembl chr 7:132,976,620...132,981,844
JBrowse link
G Lep leptin multiple interactions EXP morin analog inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of LEP protein] CTD PMID:24854284 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
JBrowse link
G Lhb luteinizing hormone subunit beta multiple interactions EXP morin inhibits the reaction [titanium dioxide results in increased expression of LHB protein] CTD PMID:28844848 NCBI chr 1:95,898,269...95,901,973
Ensembl chr 1:95,900,984...95,901,972
Ensembl chr 1:95,900,984...95,901,972
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions EXP morin inhibits the reaction [Excitatory Amino Acid Agonists results in increased phosphorylation of MAPK1 protein] CTD PMID:19201465 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions EXP morin inhibits the reaction [Excitatory Amino Acid Agonists results in increased phosphorylation of MAPK3 protein] CTD PMID:19201465 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions EXP morin inhibits the reaction [Ifosfamide results in increased activity of MAPK8 protein] CTD PMID:31722249 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Mgst1 microsomal glutathione S-transferase 1 multiple interactions EXP [1,2-Dimethylhydrazine co-treated with morin] results in increased expression of MGST1 mRNA CTD PMID:32028820 NCBI chr 4:171,029,666...171,044,893
Ensembl chr 4:171,029,630...171,044,892
JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions EXP morin inhibits the reaction [Diethylnitrosamine results in increased expression of MMP2 protein] CTD PMID:19539802 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions
decreases expression
EXP
ISO
morin inhibits the reaction [Diethylnitrosamine results in increased expression of MMP9 protein]
morin results in decreased expression of MMP9 mRNA
CTD PMID:16304905 PMID:19539802 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Mtor mechanistic target of rapamycin kinase increases expression ISO morin results in increased expression of MTOR mRNA CTD PMID:28689916 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions EXP [1,2-Dimethylhydrazine co-treated with morin] affects the localization of NFE2L2 protein; morin inhibits the reaction [Acetaminophen results in decreased expression of and affects the localization of NFE2L2 protein]; morin inhibits the reaction [Acetaminophen results in increased ubiquitination of and results in decreased expression of NFE2L2 protein]; morin inhibits the reaction [Ifosfamide results in decreased expression of NFE2L2 protein] CTD PMID:26767949 PMID:31722249 PMID:32028820 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nos1 nitric oxide synthase 1 multiple interactions EXP morin inhibits the reaction [Ifosfamide results in increased activity of NOS1 protein] CTD PMID:31722249 NCBI chr12:38,615,111...38,795,492
Ensembl chr12:38,626,714...38,710,945
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO
EXP
morin inhibits the reaction [[Lipopolysaccharides co-treated with Thioglycolates] results in increased expression of NOS2 mRNA]
[morin co-treated with Indomethacin] inhibits the reaction [Freund's Adjuvant results in increased expression of NOS2 mRNA]; morin inhibits the reaction [Freund's Adjuvant results in increased expression of NOS2 mRNA]
CTD PMID:22698256 PMID:25698669 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions EXP morin inhibits the reaction [Acetaminophen results in decreased activity of NQO1 protein]; morin inhibits the reaction [Acetaminophen results in decreased expression of NQO1 protein]
Morin enhances the reaction [Carbon tetrachloride increases expression of Nqo1 mRNA in liver]
CTD
RGD
PMID:26767949 PMID:29307993 RGD:25823195 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 multiple interactions EXP morin inhibits the reaction [Streptozocin results in increased expression of NTRK2 mRNA] CTD PMID:35414346 NCBI chr17:5,558,992...5,870,299
Ensembl chr17:5,559,043...5,869,136
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases expression ISO morin results in increased expression of PARP1 mRNA CTD PMID:28689916 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Pdk1 pyruvate dehydrogenase kinase 1 multiple interactions EXP morin inhibits the reaction [Diethylnitrosamine results in increased expression of PDK1 protein modified form] CTD PMID:19931519 NCBI chr 3:56,705,824...56,733,040
Ensembl chr 3:56,705,871...56,733,038
JBrowse link
G Phlpp2 PH domain and leucine rich repeat protein phosphatase 2 multiple interactions EXP morin inhibits the reaction [Acetaminophen results in increased expression of PHLPP2 protein] CTD PMID:26767949 NCBI chr19:37,835,125...37,901,804
Ensembl chr19:37,835,125...37,905,513
JBrowse link
G Pik3cb phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta increases expression ISO morin results in increased expression of PIK3CB mRNA CTD PMID:28689916 NCBI chr 8:99,594,600...99,699,772
Ensembl chr 8:99,594,644...99,699,663
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma affects localization
multiple interactions
affects binding
ISO morin affects the localization of PPARG protein
2-chloro-5-nitrobenzanilide inhibits the reaction [morin promotes the reaction [PPARG protein binds to SP1 protein]]; morin promotes the reaction [PPARG protein binds to SP1 protein]
morin binds to PPARG protein
CTD PMID:36121554 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Prkab1 protein kinase AMP-activated non-catalytic subunit beta 1 decreases expression ISO morin results in decreased expression of PRKAB1 mRNA CTD PMID:28689916 NCBI chr12:40,588,140...40,598,673
Ensembl chr12:40,588,211...40,598,661
JBrowse link
G Prkce protein kinase C, epsilon decreases expression ISO morin results in decreased expression of PRKCE mRNA CTD PMID:28689916 NCBI chr 6:7,965,048...8,451,966
Ensembl chr 6:7,965,048...8,451,719
JBrowse link
G Pten phosphatase and tensin homolog multiple interactions EXP morin inhibits the reaction [Diethylnitrosamine results in decreased expression of PTEN protein modified form] CTD PMID:19931519 NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP [morin co-treated with Indomethacin] inhibits the reaction [Freund's Adjuvant results in increased expression of PTGS2 mRNA]; Indomethacin promotes the reaction [morin inhibits the reaction [Freund's Adjuvant results in increased expression of PTGS2 protein]]; morin inhibits the reaction [Diethylnitrosamine results in increased expression of PTGS2 mRNA]; morin inhibits the reaction [Diethylnitrosamine results in increased expression of PTGS2 protein]; morin inhibits the reaction [Freund's Adjuvant results in increased expression of PTGS2 mRNA]; morin inhibits the reaction [Freund's Adjuvant results in increased expression of PTGS2 protein]; morin promotes the reaction [Indomethacin inhibits the reaction [Freund's Adjuvant results in increased expression of PTGS2 protein]] CTD PMID:19539802 PMID:25698669 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Ptpn1 protein tyrosine phosphatase, non-receptor type 1 decreases activity ISO morin results in decreased activity of PTPN1 protein CTD PMID:29175190 NCBI chr 3:156,638,811...156,687,503
Ensembl chr 3:156,638,769...156,687,504
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions EXP [morin co-treated with Indomethacin] inhibits the reaction [Freund's Adjuvant results in increased expression of RELA mRNA]; Indomethacin promotes the reaction [morin inhibits the reaction [Freund's Adjuvant results in increased expression of RELA protein]]; morin inhibits the reaction [Diethylnitrosamine results in increased expression of RELA mRNA]; morin inhibits the reaction [Diethylnitrosamine results in increased expression of RELA protein]; morin inhibits the reaction [Diethylnitrosamine results in increased localization of RELA protein]; morin inhibits the reaction [Excitatory Amino Acid Agonists affects the localization of and results in increased activity of RELA protein]; morin inhibits the reaction [Freund's Adjuvant results in increased expression of RELA mRNA]; morin inhibits the reaction [Freund's Adjuvant results in increased expression of RELA protein]; morin promotes the reaction [Indomethacin inhibits the reaction [Freund's Adjuvant results in increased expression of RELA protein]] CTD PMID:19201465 PMID:19539802 PMID:25698669 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 increases expression ISO morin results in increased expression of RPS6KB1 mRNA CTD PMID:28689916 NCBI chr10:71,323,777...71,367,908
Ensembl chr10:71,323,777...71,367,908
JBrowse link
G Slc16a1 solute carrier family 16 member 1 multiple interactions ISO
EXP
morin inhibits the reaction [SLC16A1 protein results in increased uptake of Benzoic Acid]
[morin results in decreased activity of SLC16A1 protein] which results in decreased uptake of Sodium Oxybate
CTD PMID:17108059 PMID:17976262 NCBI chr 2:192,123,755...192,144,617
Ensembl chr 2:192,124,289...192,144,611
JBrowse link
G Sp1 Sp1 transcription factor multiple interactions ISO 2-chloro-5-nitrobenzanilide inhibits the reaction [morin promotes the reaction [PPARG protein binds to SP1 protein]]; morin promotes the reaction [PPARG protein binds to SP1 protein] CTD PMID:36121554 NCBI chr 7:133,541,302...133,571,961
Ensembl chr 7:133,541,491...133,571,961
JBrowse link
G Spmip11 sperm microtubule inner protein 11 multiple interactions EXP morin inhibits the reaction [Doxorubicin affects the expression of NPHS1 protein] CTD PMID:31100273 NCBI chr 7:129,720,950...129,742,485
Ensembl chr 7:129,720,950...129,742,485
JBrowse link
G Star steroidogenic acute regulatory protein multiple interactions EXP morin inhibits the reaction [titanium dioxide results in decreased expression of STAR mRNA] CTD PMID:28844848 NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions EXP morin inhibits the reaction [Dimethylnitrosamine results in increased expression of TGFB1 mRNA]; morin inhibits the reaction [Dimethylnitrosamine results in increased expression of TGFB1 protein] CTD PMID:18629640 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO
EXP
morin inhibits the reaction [[Lipopolysaccharides co-treated with Thioglycolates] results in increased expression of TNF mRNA]; morin inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; morin inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]
[Indomethacin co-treated with morin] inhibits the reaction [Freund's Adjuvant results in increased expression of TNF mRNA]; Indomethacin promotes the reaction [morin inhibits the reaction [Freund's Adjuvant results in increased expression of TNF protein]]; morin analog inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TNF protein]; morin inhibits the reaction [Doxorubicin results in increased expression of TNF protein]; morin inhibits the reaction [Freund's Adjuvant results in increased expression of TNF mRNA]; morin inhibits the reaction [Freund's Adjuvant results in increased expression of TNF protein]; morin inhibits the reaction [Ifosfamide results in increased expression of TNF protein]; morin inhibits the reaction [titanium dioxide results in increased expression of TNF protein]; morin promotes the reaction [Indomethacin inhibits the reaction [Freund's Adjuvant results in increased expression of TNF protein]]
CTD PMID:22698256 PMID:24854284 PMID:25698669 PMID:28844848 PMID:31100273 More... NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfrsf25 TNF receptor superfamily member 25 increases expression ISO morin results in increased expression of TNFRSF25 mRNA CTD PMID:28689916 NCBI chr 5:162,621,669...162,626,341
Ensembl chr 5:162,622,075...162,626,341
JBrowse link
G Tnfsf11 TNF superfamily member 11 multiple interactions EXP [morin co-treated with Indomethacin] inhibits the reaction [Freund's Adjuvant results in increased expression of TNFSF11 mRNA]; morin inhibits the reaction [Freund's Adjuvant results in increased expression of TNFSF11 mRNA] CTD PMID:25698669 NCBI chr15:53,673,850...53,705,325
Ensembl chr15:53,673,877...53,705,445
JBrowse link
G Tp53 tumor protein p53 increases expression
multiple interactions
ISO
EXP
morin results in increased expression of TP53 mRNA
morin inhibits the reaction [Ifosfamide results in increased expression of TP53 protein]
CTD PMID:28689916 PMID:31722249 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Txnrd1 thioredoxin reductase 1 multiple interactions EXP [1,2-Dimethylhydrazine co-treated with morin] results in increased expression of TXNRD1 mRNA CTD PMID:32028820 NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 increases glucuronidation
multiple interactions
decreases activity
ISO UGT1A1 protein results in increased glucuronidation of morin
AHR gene mutant form inhibits the reaction [morin results in increased expression of UGT1A1 mRNA]
morin results in decreased activity of UGT1A1 protein
CTD PMID:14557274 PMID:29584932 PMID:35063619 NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465
JBrowse link
G Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2 decreases activity ISO morin results in decreased activity of UGT1A3 protein CTD PMID:35063619 NCBI chr 9:88,791,216...88,808,465
Ensembl chr 9:88,713,184...88,808,465
JBrowse link
G Ugt1a3 UDP glycosyltransferase 1 family, polypeptide A3 multiple interactions EXP [1,2-Dimethylhydrazine co-treated with morin] results in increased expression of UGT1A5 mRNA CTD PMID:32028820 NCBI chr 9:88,780,328...88,808,465
Ensembl chr 9:88,713,184...88,808,465
JBrowse link
G Ugt1a6 UDP glucuronosyltransferase family 1 member A6 decreases activity ISO morin results in decreased activity of UGT1A6 protein CTD PMID:35063619 NCBI chr 9:88,747,213...88,808,465
Ensembl chr 9:88,713,184...88,808,465
JBrowse link
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 increases glucuronidation
decreases activity
ISO UGT1A9 protein results in increased glucuronidation of morin
morin results in decreased activity of UGT1A9 protein
CTD PMID:14557274 PMID:35063619 NCBI chr 9:88,696,981...88,808,465
Ensembl chr 9:88,713,184...88,808,465
JBrowse link
G Ugt2b7 UDP glucuronosyltransferase family 2 member B7 decreases activity ISO morin results in decreased activity of UGT2B7 protein CTD PMID:35063619 NCBI chr14:20,896,682...20,919,604
Ensembl chr14:20,896,682...20,919,604
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions EXP Indomethacin promotes the reaction [morin inhibits the reaction [Freund's Adjuvant results in increased expression of VEGFA protein]]; morin inhibits the reaction [Freund's Adjuvant results in increased expression of VEGFA protein]; morin promotes the reaction [Indomethacin inhibits the reaction [Freund's Adjuvant results in increased expression of VEGFA protein]] CTD PMID:25698669 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
G Wee1 WEE1 G2 checkpoint kinase increases expression ISO morin results in increased expression of WEE1 mRNA CTD PMID:28689916 NCBI chr 1:164,173,681...164,197,688
Ensembl chr 1:164,174,779...164,197,688
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19918
    role 19894
      chemical role 19512
        antioxidant 16062
          morin 106
Path 2
Term Annotations click to browse term
  CHEBI ontology 19918
    subatomic particle 19916
      composite particle 19916
        hadron 19916
          baryon 19916
            nucleon 19916
              atomic nucleus 19916
                atom 19916
                  main group element atom 19866
                    p-block element atom 19866
                      carbon group element atom 19811
                        carbon atom 19806
                          organic molecular entity 19806
                            organic molecule 19758
                              organic cyclic compound 19565
                                organic heterocyclic compound 18906
                                  oxacycle 17850
                                    benzopyran 11796
                                      1-benzopyran 11539
                                        flavonoid 6906
                                          anthoxanthin 4541
                                            flavones 4541
                                              hydroxyflavone 4519
                                                flavonols 4410
                                                  7-hydroxyflavonol 4387
                                                    morin 106
paths to the root