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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:morin
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Accession:CHEBI:75092 term browser browse the term
Definition:A pentahydroxyflavone that is 7-hydroxyflavonol bearing three additional hydroxy substituents at positions 2' 4' and 5.
Synonyms:exact_synonym: 2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chromen-4-one
 related_synonym: 2',4',3,5,7-Pentahydroxyflavone;   2',4',5,7-Tetrahydroxyflavan-3-ol;   2',4',5,7-Tetrahydroxyflavonol;   2-(2,4-Dihydroxyphenyl)-3,5,7-trihydroxy-4H-1-benzopyran-4-one;   C.I.Natural Yellow 8;   Formula=C15H10O7;   InChI=1S/C15H10O7/c16-6-1-2-8(9(18)3-6)15-14(21)13(20)12-10(19)4-7(17)5-11(12)22-15/h1-5,16-19,21H;   InChIKey=YXOLAZRVSSWPPT-UHFFFAOYSA-N;   SMILES=Oc1ccc(c(O)c1)-c1oc2cc(O)cc(O)c2c(=O)c1O
 alt_id: CHEBI:6998
 xref: CAS:480-16-0;   HMDB:HMDB0030796;   KEGG:C10105;   KNApSAcK:C00004624;   LINCS:LSM-36988;   LIPID_MAPS_instance:LMPK12112517
 xref_mesh: MESH:C008548
 xref: PMID:15516722;   PMID:16806951;   PMID:18629640;   PMID:19539802;   PMID:19774509;   PMID:22740350;   PMID:23030699;   PMID:23254912;   PMID:23279849;   PMID:23352912;   PMID:23384060;   PMID:23432089;   PMID:23590821;   PMID:23757948;   PMID:23952478;   Reaxys:327474;   Wikipedia:Morin_(flavonol)


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morin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 decreases activity
multiple interactions		 ISO morin results in decreased activity of ABCB11 protein
morin inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid]		 CTD PMID:24014644 NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730 		JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 decreases activity ISO morin results in decreased activity of ABCC1 protein CTD PMID:15670588 NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114 		JBrowse link
G Ache acetylcholinesterase multiple interactions EXP morin inhibits the reaction [Ifosfamide results in increased activity of ACHE protein] CTD PMID:31722249 NCBI chr12:19,407,359...19,413,713
Ensembl chr12:19,407,360...19,413,651 		JBrowse link
G Acta2 actin alpha 2, smooth muscle multiple interactions EXP morin inhibits the reaction [Dimethylnitrosamine results in increased expression of ACTA2 mRNA]; morin inhibits the reaction [Dimethylnitrosamine results in increased expression of ACTA2 protein] CTD PMID:18629640 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554 		JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing multiple interactions EXP morin analog inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of ADIPOQ protein] CTD PMID:24854284 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564 		JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions ISO AHR gene mutant form inhibits the reaction [morin results in increased expression of CYP1A1 mRNA]; AHR gene mutant form inhibits the reaction [morin results in increased expression of UGT1A1 mRNA] CTD PMID:29584932 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 multiple interactions EXP morin inhibits the reaction [Excitatory Amino Acid Agonists affects the localization of AIFM1 protein] CTD PMID:19201465 NCBI chr  X:127,650,223...127,689,356
Ensembl chr  X:127,650,226...127,689,256 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions
increases expression		 EXP
ISO		 morin inhibits the reaction [Acetaminophen results in decreased phosphorylation of AKT1 protein]; morin inhibits the reaction [Excitatory Amino Acid Agonists results in decreased phosphorylation of AKT1 protein]
morin results in increased expression of AKT1 mRNA		 CTD PMID:19201465 PMID:26767949 PMID:28689916 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 increases expression ISO morin results in increased expression of APAF1 mRNA CTD PMID:28689916 NCBI chr 7:25,494,143...25,579,540
Ensembl chr 7:25,494,609...25,579,540 		JBrowse link
G App amyloid beta precursor protein multiple interactions ISO morin affects the reaction [APP protein binds to APP protein] CTD PMID:18537544 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561 		JBrowse link
G Aqp2 aquaporin 2 multiple interactions EXP morin inhibits the reaction [Doxorubicin affects the expression of AQP2 protein] CTD PMID:31100273 NCBI chr 7:130,711,433...130,716,468
Ensembl chr 7:130,711,413...130,716,468 		JBrowse link
G Ar androgen receptor decreases expression ISO morin results in decreased expression of AR mRNA CTD PMID:24726691 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions
increases expression		 EXP
ISO		 morin inhibits the reaction [Acetaminophen results in increased expression of BAX protein]; morin inhibits the reaction [Diethylnitrosamine results in decreased expression of BAX protein]; morin inhibits the reaction [Doxorubicin affects the expression of BAX protein]; morin inhibits the reaction [Excitatory Amino Acid Agonists results in increased expression of BAX protein]; morin inhibits the reaction [titanium dioxide results in increased expression of BAX mRNA]
morin results in increased expression of BAX mRNA		 CTD PMID:19201465 PMID:19931519 PMID:26767949 PMID:28689916 PMID:28844848 More... NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bche butyrylcholinesterase multiple interactions EXP morin inhibits the reaction [Ifosfamide results in increased activity of BCHE protein] CTD PMID:31722249 NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
decreases expression		 EXP
ISO		 morin inhibits the reaction [Acetaminophen results in decreased expression of BCL2 protein]; morin inhibits the reaction [Diethylnitrosamine results in increased expression of BCL2 protein]; morin inhibits the reaction [Doxorubicin results in decreased expression of BCL2 protein]; morin inhibits the reaction [Ifosfamide results in decreased expression of BCL2 mRNA]; morin inhibits the reaction [titanium dioxide results in decreased expression of BCL2 mRNA]
morin results in decreased expression of BCL2 mRNA		 CTD PMID:19931519 PMID:26767949 PMID:28689916 PMID:28844848 PMID:31100273 More... NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bcl2l1 Bcl2-like 1 decreases expression ISO morin results in decreased expression of BCL2L1 mRNA CTD PMID:28689916 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479 		JBrowse link
G Bdnf brain-derived neurotrophic factor multiple interactions EXP morin inhibits the reaction [Ifosfamide results in increased expression of BDNF mRNA] CTD PMID:31722249 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615 		JBrowse link
G Birc2 baculoviral IAP repeat-containing 2 decreases expression ISO morin results in decreased expression of BIRC2 mRNA CTD PMID:28689916 NCBI chr 8:4,968,856...4,989,325
Ensembl chr 8:4,968,842...4,988,732 		JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 decreases expression ISO morin results in decreased expression of BIRC3 mRNA CTD PMID:28689916 NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 decreases expression ISO morin results in decreased expression of BIRC5 mRNA CTD PMID:28689916 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380 		JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity		 EXP
ISO		 morin inhibits the reaction [Acetaminophen results in increased activity of CASP3 protein]; morin inhibits the reaction [Acetaminophen results in increased cleavage of CASP3 protein]; morin inhibits the reaction [Diethylnitrosamine results in decreased expression of CASP3 protein]; morin inhibits the reaction [Ifosfamide results in increased activity of CASP3 protein]; morin inhibits the reaction [titanium dioxide results in increased expression of CASP3 mRNA]
morin results in increased activity of CASP3 protein		 CTD PMID:19931519 PMID:24726691 PMID:26767949 PMID:28844848 PMID:31722249 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp7 caspase 7 increases activity ISO morin results in increased activity of CASP7 protein CTD PMID:24726691 NCBI chr 1:255,437,195...255,476,737
Ensembl chr 1:255,437,172...255,476,729 		JBrowse link
G Casp9 caspase 9 multiple interactions EXP morin inhibits the reaction [Acetaminophen results in increased activity of CASP9 protein]; morin inhibits the reaction [Diethylnitrosamine results in decreased expression of CASP9 protein] CTD PMID:19931519 PMID:26767949 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Cat catalase multiple interactions EXP Indomethacin promotes the reaction [morin inhibits the reaction [Freund's Adjuvant results in decreased activity of CAT protein]]; morin analog inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased activity of CAT protein]; morin inhibits the reaction [Acetaminophen results in decreased activity of CAT protein]; morin inhibits the reaction [Doxorubicin results in decreased activity of CAT protein]; morin inhibits the reaction [Excitatory Amino Acid Agonists results in decreased activity of CAT protein]; morin inhibits the reaction [Freund's Adjuvant results in decreased activity of CAT protein]; morin inhibits the reaction [Ifosfamide results in decreased activity of CAT protein]; morin promotes the reaction [Indomethacin inhibits the reaction [Freund's Adjuvant results in decreased activity of CAT protein]] CTD PMID:19201465 PMID:24854284 PMID:25698669 PMID:26767949 PMID:31100273 More... NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions EXP [morin co-treated with Indomethacin] inhibits the reaction [Freund's Adjuvant results in increased expression of CCL2 mRNA]; Indomethacin promotes the reaction [morin inhibits the reaction [Freund's Adjuvant results in increased expression of CCL2 protein]]; morin inhibits the reaction [Freund's Adjuvant results in increased expression of CCL2 mRNA]; morin inhibits the reaction [Freund's Adjuvant results in increased expression of CCL2 protein]; morin promotes the reaction [Indomethacin inhibits the reaction [Freund's Adjuvant results in increased expression of CCL2 protein]] CTD PMID:25698669 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Ccnb1 cyclin B1 decreases expression ISO morin results in decreased expression of CCNB1 mRNA CTD PMID:28689916 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172 		JBrowse link
G Cdc25c cell division cycle 25C decreases expression ISO morin results in decreased expression of CDC25C mRNA CTD PMID:28689916 NCBI chr18:26,335,156...26,356,199
Ensembl chr18:26,335,834...26,356,185 		JBrowse link
G Cdk1 cyclin-dependent kinase 1 decreases expression ISO morin results in decreased expression of CDK1 mRNA CTD PMID:28689916 NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO morin results in increased expression of CDKN1A mRNA CTD PMID:28689916 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Chek2 checkpoint kinase 2 decreases expression ISO morin results in decreased expression of CHEK2 mRNA CTD PMID:28689916 NCBI chr12:45,788,823...45,821,382
Ensembl chr12:45,788,827...45,821,286 		JBrowse link
G Cp ceruloplasmin multiple interactions EXP [Indomethacin co-treated with morin] inhibits the reaction [Freund's Adjuvant results in increased expression of CP protein]; morin inhibits the reaction [Freund's Adjuvant results in increased expression of CP protein] CTD PMID:25698669 NCBI chr 2:102,439,433...102,498,075
Ensembl chr 2:102,439,624...102,498,075 		JBrowse link
G Ctsd cathepsin D multiple interactions EXP [morin co-treated with Indomethacin] inhibits the reaction [Freund's Adjuvant results in increased activity of CTSD protein]; morin inhibits the reaction [Freund's Adjuvant results in increased activity of CTSD protein] CTD PMID:25698669 NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488 		JBrowse link
G Cycs cytochrome c, somatic multiple interactions EXP morin inhibits the reaction [Diethylnitrosamine results in decreased expression of CYCS protein] CTD PMID:19931519 NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
increases expression		 ISO morin affects the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]
morin results in increased expression of CYP1A1 mRNA; morin results in increased expression of CYP1A1 protein
AHR gene mutant form inhibits the reaction [morin results in increased expression of CYP1A1 mRNA]		 CTD PMID:20930378 PMID:29584932 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Diablo diablo, IAP-binding mitochondrial protein increases expression ISO morin results in increased expression of DIABLO mRNA CTD PMID:28689916 NCBI chr12:33,055,784...33,070,400
Ensembl chr12:33,055,263...33,070,387 		JBrowse link
G Dio1 iodothyronine deiodinase 1 decreases activity ISO morin results in decreased activity of DIO1 protein CTD PMID:30561685 NCBI chr 5:122,074,285...122,090,983
Ensembl chr 5:122,074,279...122,090,970 		JBrowse link
G Dio3 iodothyronine deiodinase 3 decreases activity ISO morin results in decreased activity of DIO3 protein CTD PMID:30561685 NCBI chr 6:129,285,747...129,287,608
Ensembl chr 6:129,285,749...129,286,660 		JBrowse link
G Fadd Fas associated via death domain increases expression ISO morin results in increased expression of FADD mRNA CTD PMID:28689916 NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653 		JBrowse link
G Fas Fas cell surface death receptor multiple interactions EXP morin inhibits the reaction [titanium dioxide results in increased expression of FAS mRNA] CTD PMID:28844848 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Faslg Fas ligand increases expression ISO morin results in increased expression of FASLG mRNA CTD PMID:28689916 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP morin inhibits the reaction [Ifosfamide results in increased expression of FOS protein] CTD PMID:31722249 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Fshb follicle stimulating hormone subunit beta multiple interactions EXP morin inhibits the reaction [titanium dioxide results in increased expression of FSHB protein] CTD PMID:28844848 NCBI chr 3:93,548,560...93,552,370
Ensembl chr 3:93,548,560...93,552,370 		JBrowse link
G Gfap glial fibrillary acidic protein multiple interactions EXP morin inhibits the reaction [Ifosfamide results in increased expression of GFAP protein] CTD PMID:31722249 NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589 		JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions EXP morin analog inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased activity of GPT protein]; morin inhibits the reaction [Doxorubicin results in increased activity of GPT protein] CTD PMID:24854284 PMID:31100273 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions EXP morin inhibits the reaction [Acetaminophen results in decreased phosphorylation of GSK3B protein]; morin inhibits the reaction [Diethylnitrosamine results in increased expression of GSK3B protein modified form] CTD PMID:19931519 PMID:26767949 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646 		JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions EXP morin inhibits the reaction [Acetaminophen results in decreased expression of HMOX1 protein] CTD PMID:26767949 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Ifng interferon gamma multiple interactions ISO morin inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased abundance of Nitric Oxide] CTD PMID:22698256 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Il17a interleukin 17A multiple interactions EXP [morin co-treated with Indomethacin] inhibits the reaction [Freund's Adjuvant results in increased expression of IL17A mRNA]; morin inhibits the reaction [Freund's Adjuvant results in increased expression of IL17A mRNA] CTD PMID:25698669 NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889 		JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO
EXP		 morin inhibits the reaction [[Lipopolysaccharides co-treated with Thioglycolates] results in increased expression of IL1B mRNA]; morin inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]
[morin co-treated with Indomethacin] inhibits the reaction [Freund's Adjuvant results in increased expression of IL1B mRNA]; Indomethacin promotes the reaction [morin inhibits the reaction [Freund's Adjuvant results in increased expression of IL1B protein]]; morin inhibits the reaction [Doxorubicin results in increased expression of IL1B protein]; morin inhibits the reaction [Freund's Adjuvant results in increased expression of IL1B mRNA]; morin inhibits the reaction [Freund's Adjuvant results in increased expression of IL1B protein]; morin promotes the reaction [Indomethacin inhibits the reaction [Freund's Adjuvant results in increased expression of IL1B protein]]		 CTD PMID:22698256 PMID:25698669 PMID:31100273 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il6 interleukin 6 multiple interactions ISO
EXP		 morin inhibits the reaction [[Lipopolysaccharides co-treated with Thioglycolates] results in increased expression of IL6 mRNA]; morin inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]
[morin co-treated with Indomethacin] inhibits the reaction [Freund's Adjuvant results in increased expression of IL6 mRNA]; morin inhibits the reaction [Freund's Adjuvant results in increased expression of IL6 mRNA]		 CTD PMID:22698256 PMID:25698669 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Iyd iodotyrosine deiodinase multiple interactions ISO morin inhibits the reaction [IYD protein results in increased metabolism of Monoiodotyrosine] CTD PMID:33352258 NCBI chr 1:40,003,999...40,019,323
Ensembl chr 1:40,004,041...40,019,319 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP [morin co-treated with Indomethacin] inhibits the reaction [Freund's Adjuvant results in increased expression of JUN mRNA]; morin inhibits the reaction [Freund's Adjuvant results in increased expression of JUN mRNA] CTD PMID:25698669 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656 		JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase multiple interactions EXP morin inhibits the reaction [titanium dioxide results in decreased expression of KIT mRNA] CTD PMID:28844848 NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652 		JBrowse link
G Krt1 keratin 1 multiple interactions ISO morin inhibits the reaction [Calcium results in increased expression of KRT1 mRNA] CTD PMID:12069687 NCBI chr 7:132,976,618...132,981,844
Ensembl chr 7:132,976,620...132,981,844 		JBrowse link
G Lep leptin multiple interactions EXP morin analog inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of LEP protein] CTD PMID:24854284 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262 		JBrowse link
G Lhb luteinizing hormone subunit beta multiple interactions EXP morin inhibits the reaction [titanium dioxide results in increased expression of LHB protein] CTD PMID:28844848 NCBI chr 1:95,898,269...95,901,973
Ensembl chr 1:95,900,984...95,901,972
Ensembl chr 1:95,900,984...95,901,972 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions EXP morin inhibits the reaction [Excitatory Amino Acid Agonists results in increased phosphorylation of MAPK1 protein] CTD PMID:19201465 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions EXP morin inhibits the reaction [Excitatory Amino Acid Agonists results in increased phosphorylation of MAPK3 protein] CTD PMID:19201465 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions EXP morin inhibits the reaction [Ifosfamide results in increased activity of MAPK8 protein] CTD PMID:31722249 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981 		JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions EXP morin inhibits the reaction [Diethylnitrosamine results in increased expression of MMP2 protein] CTD PMID:19539802 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870 		JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions
decreases expression		 EXP
ISO		 morin inhibits the reaction [Diethylnitrosamine results in increased expression of MMP9 protein]
morin results in decreased expression of MMP9 mRNA		 CTD PMID:16304905 PMID:19539802 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
G Mtor mechanistic target of rapamycin kinase increases expression ISO morin results in increased expression of MTOR mRNA CTD PMID:28689916 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions EXP morin inhibits the reaction [Acetaminophen results in decreased expression of and affects the localization of NFE2L2 protein]; morin inhibits the reaction [Acetaminophen results in increased ubiquitination of and results in decreased expression of NFE2L2 protein]; morin inhibits the reaction [Ifosfamide results in decreased expression of NFE2L2 protein] CTD PMID:26767949 PMID:31722249 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Nos1 nitric oxide synthase 1 multiple interactions EXP morin inhibits the reaction [Ifosfamide results in increased activity of NOS1 protein] CTD PMID:31722249 NCBI chr12:38,615,111...38,795,492
Ensembl chr12:38,626,714...38,710,945 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO
EXP		 morin inhibits the reaction [[Lipopolysaccharides co-treated with Thioglycolates] results in increased expression of NOS2 mRNA]
[morin co-treated with Indomethacin] inhibits the reaction [Freund's Adjuvant results in increased expression of NOS2 mRNA]; morin inhibits the reaction [Freund's Adjuvant results in increased expression of NOS2 mRNA]		 CTD PMID:22698256 PMID:25698669 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions EXP morin inhibits the reaction [Acetaminophen results in decreased activity of NQO1 protein]; morin inhibits the reaction [Acetaminophen results in decreased expression of NQO1 protein]
Morin enhances the reaction [Carbon tetrachloride increases expression of Nqo1 mRNA in liver] 		CTD
RGD		 PMID:26767949 PMID:29307993 RGD:25823195 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases expression ISO morin results in increased expression of PARP1 mRNA CTD PMID:28689916 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Pdk1 pyruvate dehydrogenase kinase 1 multiple interactions EXP morin inhibits the reaction [Diethylnitrosamine results in increased expression of PDK1 protein modified form] CTD PMID:19931519 NCBI chr 3:56,705,824...56,733,040
Ensembl chr 3:56,705,871...56,733,038 		JBrowse link
G Phlpp2 PH domain and leucine rich repeat protein phosphatase 2 multiple interactions EXP morin inhibits the reaction [Acetaminophen results in increased expression of PHLPP2 protein] CTD PMID:26767949 NCBI chr19:37,835,125...37,901,804
Ensembl chr19:37,835,125...37,905,513 		JBrowse link
G Pik3cb phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta increases expression ISO morin results in increased expression of PIK3CB mRNA CTD PMID:28689916 NCBI chr 8:99,594,600...99,699,772
Ensembl chr 8:99,594,644...99,699,663 		JBrowse link
G Prkab1 protein kinase AMP-activated non-catalytic subunit beta 1 decreases expression ISO morin results in decreased expression of PRKAB1 mRNA CTD PMID:28689916 NCBI chr12:40,588,140...40,598,673
Ensembl chr12:40,588,211...40,598,661 		JBrowse link
G Prkce protein kinase C, epsilon decreases expression ISO morin results in decreased expression of PRKCE mRNA CTD PMID:28689916 NCBI chr 6:7,965,048...8,451,966
Ensembl chr 6:7,965,048...8,451,719 		JBrowse link
G Pten phosphatase and tensin homolog multiple interactions EXP morin inhibits the reaction [Diethylnitrosamine results in decreased expression of PTEN protein modified form] CTD PMID:19931519 NCBI chr 1:230,631,303...230,696,754
Ensembl chr 1:230,630,338...230,696,838 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP [morin co-treated with Indomethacin] inhibits the reaction [Freund's Adjuvant results in increased expression of PTGS2 mRNA]; Indomethacin promotes the reaction [morin inhibits the reaction [Freund's Adjuvant results in increased expression of PTGS2 protein]]; morin inhibits the reaction [Diethylnitrosamine results in increased expression of PTGS2 mRNA]; morin inhibits the reaction [Diethylnitrosamine results in increased expression of PTGS2 protein]; morin inhibits the reaction [Freund's Adjuvant results in increased expression of PTGS2 mRNA]; morin inhibits the reaction [Freund's Adjuvant results in increased expression of PTGS2 protein]; morin promotes the reaction [Indomethacin inhibits the reaction [Freund's Adjuvant results in increased expression of PTGS2 protein]] CTD PMID:19539802 PMID:25698669 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Ptpn1 protein tyrosine phosphatase, non-receptor type 1 decreases activity ISO morin results in decreased activity of PTPN1 protein CTD PMID:29175190 NCBI chr 3:156,638,811...156,687,503
Ensembl chr 3:156,638,769...156,687,504 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions EXP [morin co-treated with Indomethacin] inhibits the reaction [Freund's Adjuvant results in increased expression of RELA mRNA]; Indomethacin promotes the reaction [morin inhibits the reaction [Freund's Adjuvant results in increased expression of RELA protein]]; morin inhibits the reaction [Diethylnitrosamine results in increased expression of RELA mRNA]; morin inhibits the reaction [Diethylnitrosamine results in increased expression of RELA protein]; morin inhibits the reaction [Diethylnitrosamine results in increased localization of RELA protein]; morin inhibits the reaction [Excitatory Amino Acid Agonists affects the localization of and results in increased activity of RELA protein]; morin inhibits the reaction [Freund's Adjuvant results in increased expression of RELA mRNA]; morin inhibits the reaction [Freund's Adjuvant results in increased expression of RELA protein]; morin promotes the reaction [Indomethacin inhibits the reaction [Freund's Adjuvant results in increased expression of RELA protein]] CTD PMID:19201465 PMID:19539802 PMID:25698669 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 increases expression ISO morin results in increased expression of RPS6KB1 mRNA CTD PMID:28689916 NCBI chr10:71,323,777...71,367,908
Ensembl chr10:71,323,777...71,367,908 		JBrowse link
G Slc16a1 solute carrier family 16 member 1 multiple interactions ISO
EXP		 morin inhibits the reaction [SLC16A1 protein results in increased uptake of Benzoic Acid]
[morin results in decreased activity of SLC16A1 protein] which results in decreased uptake of Sodium Oxybate		 CTD PMID:17108059 PMID:17976262 NCBI chr 2:192,123,755...192,144,617
Ensembl chr 2:192,124,289...192,144,611 		JBrowse link
G Star steroidogenic acute regulatory protein multiple interactions EXP morin inhibits the reaction [titanium dioxide results in decreased expression of STAR mRNA] CTD PMID:28844848 NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions EXP morin inhibits the reaction [Dimethylnitrosamine results in increased expression of TGFB1 mRNA]; morin inhibits the reaction [Dimethylnitrosamine results in increased expression of TGFB1 protein] CTD PMID:18629640 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO
EXP		 morin inhibits the reaction [[Lipopolysaccharides co-treated with Thioglycolates] results in increased expression of TNF mRNA]; morin inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; morin inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]
[Indomethacin co-treated with morin] inhibits the reaction [Freund's Adjuvant results in increased expression of TNF mRNA]; Indomethacin promotes the reaction [morin inhibits the reaction [Freund's Adjuvant results in increased expression of TNF protein]]; morin analog inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TNF protein]; morin inhibits the reaction [Doxorubicin results in increased expression of TNF protein]; morin inhibits the reaction [Freund's Adjuvant results in increased expression of TNF mRNA]; morin inhibits the reaction [Freund's Adjuvant results in increased expression of TNF protein]; morin inhibits the reaction [Ifosfamide results in increased expression of TNF protein]; morin inhibits the reaction [titanium dioxide results in increased expression of TNF protein]; morin promotes the reaction [Indomethacin inhibits the reaction [Freund's Adjuvant results in increased expression of TNF protein]]		 CTD PMID:22698256 PMID:24854284 PMID:25698669 PMID:28844848 PMID:31100273 More... NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfrsf25 TNF receptor superfamily member 25 increases expression ISO morin results in increased expression of TNFRSF25 mRNA CTD PMID:28689916 NCBI chr 5:162,621,669...162,626,341
Ensembl chr 5:162,622,075...162,626,341 		JBrowse link
G Tnfsf11 TNF superfamily member 11 multiple interactions EXP [morin co-treated with Indomethacin] inhibits the reaction [Freund's Adjuvant results in increased expression of TNFSF11 mRNA]; morin inhibits the reaction [Freund's Adjuvant results in increased expression of TNFSF11 mRNA] CTD PMID:25698669 NCBI chr15:53,674,990...53,705,171
Ensembl chr15:53,673,877...53,705,445 		JBrowse link
G Tp53 tumor protein p53 increases expression
multiple interactions		 ISO
EXP		 morin results in increased expression of TP53 mRNA
morin inhibits the reaction [Ifosfamide results in increased expression of TP53 protein]		 CTD PMID:28689916 PMID:31722249 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 increases glucuronidation
multiple interactions		 ISO UGT1A1 protein results in increased glucuronidation of morin
AHR gene mutant form inhibits the reaction [morin results in increased expression of UGT1A1 mRNA]		 CTD PMID:14557274 PMID:29584932 NCBI chr 9:88,801,344...88,808,465 JBrowse link
G Ugt1a8 UDP glucuronosyltransferase family 1 member A8 increases glucuronidation ISO UGT1A8 protein results in increased glucuronidation of morin CTD PMID:14557274 NCBI chr 9:88,727,094...88,808,465 JBrowse link
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 increases glucuronidation ISO UGT1A9 protein results in increased glucuronidation of morin CTD PMID:14557274 NCBI chr 9:88,696,981...88,808,465 JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions EXP Indomethacin promotes the reaction [morin inhibits the reaction [Freund's Adjuvant results in increased expression of VEGFA protein]]; morin inhibits the reaction [Freund's Adjuvant results in increased expression of VEGFA protein]; morin promotes the reaction [Indomethacin inhibits the reaction [Freund's Adjuvant results in increased expression of VEGFA protein]] CTD PMID:25698669 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
G Wee1 WEE1 G2 checkpoint kinase increases expression ISO morin results in increased expression of WEE1 mRNA CTD PMID:28689916 NCBI chr 1:164,173,681...164,197,688
Ensembl chr 1:164,174,779...164,197,688 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19795
    role 19746
      chemical role 19316
        antioxidant 14437
          morin 89
Path 2
Term Annotations click to browse term
  CHEBI ontology 19795
    subatomic particle 19794
      composite particle 19794
        hadron 19794
          baryon 19794
            nucleon 19794
              atomic nucleus 19794
                atom 19794
                  main group element atom 19693
                    p-block element atom 19693
                      carbon group element atom 19614
                        carbon atom 19604
                          organic molecular entity 19604
                            organic molecule 19545
                              organic cyclic compound 19339
                                organic heterocyclic compound 18579
                                  oxacycle 17602
                                    benzopyran 11160
                                      1-benzopyran 10901
                                        flavonoid 6520
                                          flavones 4207
                                            hydroxyflavone 4195
                                              flavonols 4105
                                                7-hydroxyflavonol 4083
                                                  morin 89
paths to the root