The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
A carbobicyclic compound that is bicyclo[3.1.1]hept-2-ene which is substituted by a hydroxymethyl group at position 2, a 2,6-dimethoxy-4-(2-methyloctan-2-yl)phenyl group at position 4, and two methyl groups at position 6 (the 1S,4S,5S stereoisomer). A highly selective and effective cannabinoid type-2 agonist and the enantiomer of HU-433.
ATG5 protein affects the reaction [HU 308 inhibits the reaction [[Dextran Sulfate co-treated with Lipopolysaccharides] results in increased cleavage of CASP1 protein]]; ATG5 protein affects the reaction [HU 308 inhibits the reaction [[Dextran Sulfate co-treated with Lipopolysaccharides] results in increased secretion of IL1B protein]]
[HU 308 co-treated with Dextran Sulfate] affects the expression of BECN1 protein; HU 308 inhibits the reaction [Glucose results in decreased expression of BECN1 protein]; HU 308 inhibits the reaction [Streptozocin results in decreased expression of BECN1 protein]; HU 308 promotes the reaction [[Dextran Sulfate co-treated with Lipopolysaccharides] results in increased expression of BECN1 protein]
3-methyladenine affects the reaction [[HU 308 co-treated with Dextran Sulfate] affects the cleavage of CASP1 protein]; [HU 308 co-treated with Dextran Sulfate] affects the cleavage of CASP1 protein; ATG5 protein affects the reaction [HU 308 inhibits the reaction [[Dextran Sulfate co-treated with Lipopolysaccharides] results in increased cleavage of CASP1 protein]]; dorsomorphin inhibits the reaction [HU 308 inhibits the reaction [[Dextran Sulfate co-treated with Lipopolysaccharides] results in increased cleavage of CASP1 protein]]; HU 308 inhibits the reaction [[Dextran Sulfate co-treated with Lipopolysaccharides] results in increased cleavage of CASP1 protein]
HU 308 inhibits the reaction [IL1B protein results in increased expression of CCL2 mRNA]; HU 308 inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA]
HU 308 promotes the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of CNR2 mRNA]; HU 308 promotes the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of CNR2 protein] [HU 308 co-treated with lipopolysaccharide, E. coli O26-B6] results in increased expression of CNR2 mRNA; HU 308 binds to and results in increased activity of CNR2 protein
HU 308 promotes the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of IL10 protein] HU 308 promotes the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of IL10 mRNA]
HU 308 inhibits the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of IL1B mRNA] 3-methyladenine affects the reaction [[HU 308 co-treated with Dextran Sulfate] affects the expression of IL1B protein]; [HU 308 co-treated with Dextran Sulfate] affects the expression of IL1B protein; ATG5 protein affects the reaction [HU 308 inhibits the reaction [[Dextran Sulfate co-treated with Lipopolysaccharides] results in increased secretion of IL1B protein]]; dorsomorphin inhibits the reaction [HU 308 inhibits the reaction [[Dextran Sulfate co-treated with Lipopolysaccharides] results in increased expression of IL1B protein]]; HU 308 inhibits the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of IL1B protein]; HU 308 inhibits the reaction [[Dextran Sulfate co-treated with Lipopolysaccharides] results in increased expression of and results in increased secretion of IL1B protein]; HU 308 inhibits the reaction [[Dextran Sulfate co-treated with Lipopolysaccharides] results in increased secretion of IL1B protein] HU 308 inhibits the reaction [IL1B protein results in increased expression of CCL2 mRNA]; HU 308 inhibits the reaction [IL1B protein results in increased expression of IL6 mRNA]; HU 308 inhibits the reaction [IL1B protein results in increased expression of MMP1 mRNA]; HU 308 inhibits the reaction [IL1B protein results in increased expression of MMP3 mRNA]
HU 308 inhibits the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of IL6 mRNA] HU 308 inhibits the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of IL6 protein] HU 308 inhibits the reaction [IL1B protein results in increased expression of IL6 mRNA]
HU 308 inhibits the reaction [IL1B protein results in increased expression of MMP1 mRNA]; HU 308 inhibits the reaction [TNF protein results in increased expression of MMP1 mRNA]
HU 308 inhibits the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in increased phosphorylation of MTOR protein] HU 308 inhibits the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in increased phosphorylation of MTOR protein]; HU 308 inhibits the reaction [Glucose results in increased phosphorylation of MTOR protein]
[HU 308 co-treated with Dextran Sulfate] affects the expression of SQSTM1 protein; HU 308 inhibits the reaction [Glucose results in increased expression of SQSTM1 protein]; HU 308 inhibits the reaction [Streptozocin results in increased expression of SQSTM1 protein]; HU 308 promotes the reaction [[Dextran Sulfate co-treated with Lipopolysaccharides] results in decreased expression of SQSTM1 protein]
HU 308 promotes the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of TGFB1 mRNA] HU 308 promotes the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of TGFB1 protein]
HU 308 inhibits the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of TNF mRNA] HU 308 inhibits the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of TNF protein] HU 308 inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA]; HU 308 inhibits the reaction [TNF protein results in increased expression of CSF2 mRNA]; HU 308 inhibits the reaction [TNF protein results in increased expression of MMP1 mRNA]