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ONTOLOGY REPORT - ANNOTATIONS


Term:ajmalicine
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Accession:CHEBI:2524 term browser browse the term
Definition:A monoterpenoid indole alkaloid with formula C21H24N2O3, isolated from several Rauvolfia and Catharanthus species. It is a selective alpha1-adrenoceptor antagonist used for the treatment of high blood pressure.
Synonyms:exact_synonym: methyl (19alpha)-19-methyl-16,17-didehydro-18-oxayohimban-16-carboxylate
 related_synonym: (19alpha)-16,17-didehydro-19-methyl-oxayohimban-16-carboxylic acid methyl ester;   Circolene;   Cristanyl;   Duxil;   Formula=C21H24N2O3;   InChI=1S/C21H24N2O3/c1-12-16-10-23-8-7-14-13-5-3-4-6-18(13)22-20(14)19(23)9-15(16)17(11-26-12)21(24)25-2/h3-6,11-12,15-16,19,22H,7-10H2,1-2H3/t12-,15-,16+,19-/m0/s1;   InChIKey=GRTOGORTSDXSFK-XJTZBENFSA-N;   Lamuran;   Raubasine;   SMILES=C=1C=CC=2NC=3[C@]4(N(CCC3C2C1)C[C@]5([C@@](C(=CO[C@H]5C)C(OC)=O)(C4)[H])[H])[H];   Sarpan;   ajmalicin;   delta-yohimbine;   methyl (4S,4aR,13bS,14aS)-4-methyl-4a,5,7,8,13,13b,14,14a-octahydro-4H-indolo[2,3-a]pyrano[3,4-g]quinolizine-1-carboxylate
 xref: CAS:483-04-5 "ChemIDplus";   CAS:483-04-5 "KEGG COMPOUND";   CAS:483-04-5 "NIST Chemistry WebBook";   KEGG:C09024;   KEGG:D08470;   KNApSAcK:C00001678;   LINCS:LSM-15373
 xref_mesh: MESH:C005709
 xref: PMID:15930738 "Europe PMC";   PMID:19151732 "Europe PMC";   PMID:22331368 "Europe PMC";   PMID:22332772 "Europe PMC";   PMID:24237015 "Europe PMC";   PMID:26983347 "Europe PMC";   PMID:27584856 "Europe PMC";   PMID:4387608 "Europe PMC";   PMID:6091834 "Europe PMC";   PMID:6128043 "Europe PMC";   Reaxys:97268 "Reaxys";   Wikipedia:Ajmalicine
 cyclic_relationship: is_conjugate_base_of CHEBI:142527


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ajmalicine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 JBrowse link 7 123,599,264 123,608,436 RGD:6480464

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Term Annotations click to browse term
  CHEBI ontology 19662
    role 19606
      application 19232
        fuel 10305
          methanol 2948
            methyl ester 2939
              ajmalicine 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19662
    subatomic particle 19658
      composite particle 19658
        hadron 19658
          baryon 19658
            nucleon 19658
              atomic nucleus 19658
                atom 19658
                  main group element atom 19539
                    p-block element atom 19539
                      chalcogen 19228
                        oxygen atom 19182
                          oxygen molecular entity 19182
                            hydroxides 18964
                              organic hydroxy compound 18510
                                alcohol 14920
                                  aliphatic alcohol 11057
                                    alkyl alcohol 11010
                                      methanol 2948
                                        methyl ester 2939
                                          ajmalicine 1
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