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ONTOLOGY REPORT - ANNOTATIONS


Term:alprenolol
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Accession:CHEBI:51211 term browser browse the term
Definition:A secondary alcohol that is propan-2-ol substituted by a 2-allylphenoxy group at position 1 and an isopropylamino group at position 3. It is a beta-adrenergic antagonist used as a antihypertensive, anti-arrhythmia and a sympatholytic agent.
Synonyms:exact_synonym: 1-[2-(propen-2-ylphenoxy)]-3-(isopropylamino)propan-2-ol
 related_synonym: 1-(2-Allylphenoxy)-3-isopropylamino-2-propanol;   1-(o-Allylphenoxy)-3-(isopropylamino)-2-propanol;   Alfeprol;   Formula=C15H23NO2;   InChI=1S/C15H23NO2/c1-4-7-13-8-5-6-9-15(13)18-11-14(17)10-16-12(2)3/h4-6,8-9,12,14,16-17H,1,7,10-11H2,2-3H3;   InChIKey=PAZJSJFMUHDSTF-UHFFFAOYSA-N;   SMILES=CC(C)NCC(O)COc1ccccc1CC=C;   alprenololum
 xref: Beilstein:1913441 "Beilstein";   CAS:13655-52-2 "ChemIDplus";   DrugBank:DB00866;   Drug_Central:137 "DrugCentral";   HMDB:HMDB0015004;   KEGG:D07156;   LINCS:LSM-1238
 xref_mesh: MESH:D000526
 xref: PMID:19203609 "Europe PMC";   PMID:19882938 "Europe PMC";   PMID:21958537 "Europe PMC";   PMID:22841109 "Europe PMC";   Patent:NL6605692;   Patent:NL6612958;   Reaxys:1913441 "Reaxys";   Wikipedia:Alprenolol


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alprenolol term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adrb1 adrenoceptor beta 1 JBrowse link 1 277,537,585 277,538,985 RGD:6480464
G Adrb2 adrenoceptor beta 2 JBrowse link 18 57,513,792 57,515,834 RGD:6480464
G Adrb3 adrenoceptor beta 3 JBrowse link 16 69,003,541 69,006,632 RGD:6480464
G Arrb1 arrestin, beta 1 JBrowse link 1 164,502,099 164,573,947 RGD:6480464
G Arrb2 arrestin, beta 2 JBrowse link 10 57,040,252 57,048,045 RGD:6480464
G Egfr epidermal growth factor receptor JBrowse link 14 99,919,485 100,104,136 RGD:6480464
G Gnas GNAS complex locus JBrowse link 3 172,374,957 172,434,988 RGD:6480464
G Grk2 G protein-coupled receptor kinase 2 JBrowse link 1 219,536,220 219,544,329 RGD:6480464
G Hbegf heparin-binding EGF-like growth factor JBrowse link 18 29,330,302 29,340,185 RGD:6480464
G Htr2a 5-hydroxytryptamine receptor 2A JBrowse link 15 56,666,152 56,732,469 RGD:6480464
G Mapk1 mitogen activated protein kinase 1 JBrowse link 11 88,203,863 88,273,301 RGD:6480464
G Mapk3 mitogen activated protein kinase 3 JBrowse link 1 198,192,773 198,198,975 RGD:6480464
G Mir125a microRNA 125a JBrowse link 1 59,704,827 59,704,911 RGD:6480464
G Mir125b1 microRNA 125b-1 JBrowse link 8 45,798,260 45,798,346 RGD:6480464
G Mir150 microRNA 150 JBrowse link 1 101,115,974 101,116,058 RGD:6480464
G Nppa natriuretic peptide A JBrowse link 5 164,808,407 164,809,716 RGD:6480464
G Odc1 ornithine decarboxylase 1 JBrowse link 6 42,852,529 42,859,142 RGD:6480464
G Ren renin JBrowse link 13 50,502,724 50,513,953 RGD:6480464
G Slc22a2 solute carrier family 22 member 2 JBrowse link 1 48,318,025 48,360,219 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19669
    role 19613
      application 19235
        pharmaceutical 19097
          drug 19097
            cardiovascular drug 7550
              antihypertensive agent 1637
                alprenolol 19
                  alprenolol hydrochloride 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19669
    subatomic particle 19665
      composite particle 19665
        hadron 19665
          baryon 19665
            nucleon 19665
              atomic nucleus 19665
                atom 19665
                  main group element atom 19545
                    main group molecular entity 19545
                      s-block molecular entity 19329
                        hydrogen molecular entity 19319
                          hydrides 18242
                            inorganic hydride 17104
                              pnictogen hydride 17062
                                nitrogen hydride 16885
                                  azane 16564
                                    ammonia 16561
                                      organic amino compound 16560
                                        secondary amino compound 6358
                                          alprenolol 19
                                            alprenolol hydrochloride 0
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