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G
|
Aars1
|
alanyl-tRNA synthetase 1
|
decreases expression increases expression
|
ISO
|
4-phenylbutyric acid results in decreased expression of AARS1 mRNA 4-phenylbutyric acid results in increased expression of AARS1 mRNA
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CTD |
PMID:14583596 |
|
NCBI chr19:55,906,694...55,930,499
Ensembl chr19:55,906,702...55,930,497
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G
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Acsl4
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acyl-CoA synthetase long-chain family member 4
|
multiple interactions
|
ISO
|
4-phenylbutyric acid inhibits the reaction [Particulate Matter results in increased expression of ACSL4 protein]
|
CTD |
PMID:36700298 |
|
NCBI chr X:110,739,633...110,803,416
Ensembl chr X:110,739,648...110,803,261
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G
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Acta2
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actin alpha 2, smooth muscle
|
increases expression
|
ISO
|
4-phenylbutyric acid results in increased expression of ACTA2 mRNA
|
CTD |
PMID:30481203 |
|
NCBI chr 1:241,159,723...241,172,503
Ensembl chr 1:241,159,724...241,172,503
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G
|
Adam17
|
ADAM metallopeptidase domain 17
|
multiple interactions
|
ISO
|
4-phenylbutyric acid inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of ADAM17 protein]; 4-phenylbutyric acid inhibits the reaction [SFTPC protein mutant form results in increased expression of ADAM17 protein]
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CTD |
PMID:27638906 |
|
NCBI chr 6:46,601,583...46,663,690
Ensembl chr 6:46,601,583...46,649,344
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G
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Agt
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angiotensinogen
|
multiple interactions
|
EXP
|
4-phenylbutyric acid inhibits the reaction [AGT protein results in increased cleavage of SREBF1 protein]; 4-phenylbutyric acid inhibits the reaction [AGT protein results in increased expression of FN1 protein]; 4-phenylbutyric acid inhibits the reaction [AGT protein results in increased expression of SREBF1 mRNA]; 4-phenylbutyric acid inhibits the reaction [AGT protein results in increased phosphorylation of AKT1 protein]
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CTD |
PMID:25398788 |
|
NCBI chr19:69,426,540...69,447,017
Ensembl chr19:69,421,638...69,446,944
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G
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Ahsa1
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activator of Hsp90 ATPase activity 1
|
increases expression
|
ISO
|
4-phenylbutyric acid results in increased expression of AHSA1 mRNA
|
CTD |
PMID:14583596 |
|
NCBI chr 6:112,644,287...112,652,290
Ensembl chr 6:112,644,479...112,655,595
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G
|
Ajuba
|
ajuba LIM protein
|
decreases expression
|
ISO
|
4-phenylbutyric acid results in decreased expression of AJUBA mRNA
|
CTD |
PMID:14583596 |
|
NCBI chr15:31,989,796...32,000,042
Ensembl chr15:31,989,799...32,000,042
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|
G
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Akr1c1
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aldo-keto reductase family 1, member C1
|
increases expression
|
ISO
|
4-phenylbutyric acid results in increased expression of AKR1C1 mRNA
|
CTD |
PMID:14583596 |
|
NCBI chr17:70,720,397...70,747,285
Ensembl chr17:70,720,398...70,747,247
|
|
G
|
Akt1
|
AKT serine/threonine kinase 1
|
multiple interactions
|
ISO EXP
|
4-phenylbutyric acid inhibits the reaction [Curcumin results in decreased phosphorylation of AKT1 protein]; 4-phenylbutyric acid inhibits the reaction [hydroquinone results in decreased phosphorylation of AKT1 protein]; 4-phenylbutyric acid inhibits the reaction [Lipopolysaccharides results in decreased phosphorylation of AKT1 protein]; 4-phenylbutyric acid inhibits the reaction [Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of AKT1 protein]] 4-phenylbutyric acid inhibits the reaction [AGT protein results in increased phosphorylation of AKT1 protein] 4-phenylbutyric acid inhibits the reaction [titanium dioxide results in decreased phosphorylation of AKT1 protein]
|
CTD |
PMID:25398788 PMID:28245985 PMID:31298478 PMID:32283200 PMID:36640941 PMID:37148176 More...
|
|
NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610
|
|
G
|
Akt2
|
AKT serine/threonine kinase 2
|
multiple interactions
|
ISO
|
4-phenylbutyric acid inhibits the reaction [Curcumin results in decreased phosphorylation of AKT2 protein]
|
CTD |
PMID:36640941 |
|
NCBI chr 1:92,004,705...92,061,420
Ensembl chr 1:92,014,859...92,061,420
|
|
G
|
Akt3
|
AKT serine/threonine kinase 3
|
multiple interactions
|
ISO
|
4-phenylbutyric acid inhibits the reaction [Curcumin results in decreased phosphorylation of AKT3 protein]
|
CTD |
PMID:36640941 |
|
NCBI chr13:91,475,839...91,758,060
Ensembl chr13:91,475,839...91,748,020
|
|
G
|
Alpi
|
alkaline phosphatase, intestinal
|
multiple interactions
|
ISO
|
ALPI protein inhibits the reaction [4-phenylbutyric acid results in increased phosphorylation of NFE2L2 protein]
|
CTD |
PMID:32407927 |
|
NCBI chr 9:95,221,314...95,224,780
Ensembl chr 9:95,221,314...95,224,780
|
|
G
|
Apaf1
|
apoptotic peptidase activating factor 1
|
multiple interactions decreases expression
|
EXP
|
4-phenylbutyric acid inhibits the reaction [alpha-Chlorohydrin results in increased expression of APAF1 protein] 4-phenylbutyric acid results in decreased expression of APAF1 protein
|
CTD |
PMID:33651226 |
|
NCBI chr 7:27,381,392...27,466,772
Ensembl chr 7:27,381,855...27,466,772
|
|
G
|
App
|
amyloid beta precursor protein
|
affects activity
|
EXP
|
4-phenylbutyric acid affects the activity of APP protein
|
CTD |
PMID:16204253 |
|
NCBI chr11:37,506,207...37,724,351
Ensembl chr11:37,506,408...37,722,971
|
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G
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Atf4
|
activating transcription factor 4
|
multiple interactions decreases expression
|
EXP ISO
|
4-phenylbutyric acid inhibits the reaction [6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide results in increased expression of ATF4 mRNA]; 4-phenylbutyric acid inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of ATF4 mRNA]; 4-phenylbutyric acid inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of ATF4 protein]; 4-phenylbutyric acid inhibits the reaction [alpha-Chlorohydrin results in increased expression of ATF4 protein]; 4-phenylbutyric acid inhibits the reaction [Pyrazinamide results in increased expression of ATF4 protein]; 4-phenylbutyric acid inhibits the reaction [SIRT1 protein affects the expression of ATF4 mRNA]; 4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased phosphorylation of ATF4 protein]; 4-phenylbutyric acid inhibits the reaction [tetrachlorobenzoquinone results in increased expression of ATF4 protein]; 4-phenylbutyric acid inhibits the reaction [Thapsigargin results in increased expression of ATF4 protein]; 4-phenylbutyric acid inhibits the reaction [Tunicamycin results in increased expression of ATF4 protein] 4-phenylbutyric acid results in decreased expression of ATF4 protein 4-phenylbutyric acid inhibits the reaction [Acrylamide results in increased expression of ATF4 protein]; 4-phenylbutyric acid inhibits the reaction [alpha-Chlorohydrin results in increased expression of ATF4 protein]; 4-phenylbutyric acid inhibits the reaction [Cantharidin results in increased expression of ATF4 protein]; 4-phenylbutyric acid inhibits the reaction [Cisplatin results in increased expression of ATF4 protein]; 4-phenylbutyric acid inhibits the reaction [Ficusin results in increased expression of ATF4 mRNA]; 4-phenylbutyric acid inhibits the reaction [flavokawain B results in increased expression of ATF4 protein]; 4-phenylbutyric acid inhibits the reaction [Leflunomide results in increased expression of ATF4 protein]; 4-phenylbutyric acid inhibits the reaction [perhexiline maleate results in increased expression of ATF4 protein]; 4-phenylbutyric acid inhibits the reaction [Potassium Dichromate results in increased expression of ATF4 protein]; 4-phenylbutyric acid inhibits the reaction [Pyrazinamide results in increased expression of ATF4 protein]; 4-phenylbutyric acid inhibits the reaction [Rifampin results in increased expression of ATF4 mRNA]; 4-phenylbutyric acid inhibits the reaction [Rifampin results in increased expression of ATF4 protein]; 4-phenylbutyric acid inhibits the reaction [SC-66 compound results in increased expression of ATF4 protein] 4-phenylbutyric acid inhibits the reaction [3-acetyldeoxynivalenol results in increased expression of ATF4 mRNA]; 4-phenylbutyric acid inhibits the reaction [Busulfan results in increased expression of ATF4 protein]; 4-phenylbutyric acid inhibits the reaction [cyanoginosin LR results in increased expression of ATF4 protein]; 4-phenylbutyric acid inhibits the reaction [dibromoacetonitrile results in increased expression of ATF4 protein]; 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of ATF4 mRNA]; 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of ATF4 protein]; 4-phenylbutyric acid inhibits the reaction [Hydrogen Peroxide results in increased expression of ATF4 mRNA]; 4-phenylbutyric acid inhibits the reaction [Hydrogen Peroxide results in increased expression of ATF4 protein]; 4-phenylbutyric acid inhibits the reaction [Palmitic Acid results in increased expression of ATF4 mRNA]; 4-phenylbutyric acid inhibits the reaction [perfluorooctanoic acid results in increased expression of ATF4 mRNA]; 4-phenylbutyric acid inhibits the reaction [perfluorooctanoic acid results in increased expression of ATF4 protein]
|
CTD |
PMID:27470132 PMID:27484784 PMID:27634458 PMID:28063906 PMID:28844859 PMID:28988120 PMID:29653943 PMID:30025493 PMID:30602124 PMID:30980806 PMID:31364909 PMID:32578922 PMID:33309543 PMID:33651226 PMID:34175825 PMID:34533242 PMID:35398186 PMID:35413383 PMID:35533795 PMID:36030031 PMID:36473502 PMID:37741534 PMID:38065397 More...
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|
NCBI chr 7:113,684,681...113,686,739
Ensembl chr 7:113,684,681...113,686,739
|
|
G
|
Atf6
|
activating transcription factor 6
|
multiple interactions decreases expression
|
ISO EXP
|
4-phenylbutyric acid inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of ATF6 protein]; 4-phenylbutyric acid inhibits the reaction [Cadmium Chloride results in increased expression of ATF6 protein]; 4-phenylbutyric acid inhibits the reaction [Ficusin results in increased expression of ATF6 mRNA]; 4-phenylbutyric acid inhibits the reaction [Ficusin results in increased expression of ATF6 protein]; 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of ATF6 mRNA]; 4-phenylbutyric acid inhibits the reaction [hydroquinone results in decreased expression of ATF6 protein]; 4-phenylbutyric acid inhibits the reaction [hydroquinone results in increased expression of ATF6 protein]; 4-phenylbutyric acid inhibits the reaction [Lipopolysaccharides results in increased expression of ATF6 protein]; 4-phenylbutyric acid inhibits the reaction [SFTPC protein mutant form results in increased expression of ATF6 protein]; 4-phenylbutyric acid inhibits the reaction [Sodium Selenite results in increased expression of ATF6 protein]; [4-phenylbutyric acid co-treated with alpha-Chlorohydrin] results in decreased expression of ATF6 protein 4-phenylbutyric acid inhibits the reaction [Dibutyl Phthalate results in increased expression of ATF6 protein]; 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of ATF6 mRNA]; 4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased cleavage of ATF6 protein] 4-phenylbutyric acid inhibits the reaction [3-acetyldeoxynivalenol results in increased expression of ATF6 mRNA]; 4-phenylbutyric acid inhibits the reaction [Arecoline results in increased expression of ATF6 protein]; 4-phenylbutyric acid inhibits the reaction [Bilirubin results in increased expression of ATF6 mRNA]; 4-phenylbutyric acid inhibits the reaction [Cadmium Chloride results in increased expression of ATF6 mRNA]; 4-phenylbutyric acid inhibits the reaction [Cadmium Chloride results in increased expression of ATF6 protein]; 4-phenylbutyric acid inhibits the reaction [Dibutyl Phthalate results in increased expression of ATF6 protein]; 4-phenylbutyric acid inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of ATF6 protein]; 4-phenylbutyric acid inhibits the reaction [titanium dioxide results in increased cleavage of ATF6 protein]; [4-phenylbutyric acid co-treated with Palmitic Acid] results in decreased expression of ATF6 protein 4-phenylbutyric acid results in decreased expression of ATF6 protein
|
CTD |
PMID:20165829 PMID:26804720 PMID:27578021 PMID:27638906 PMID:28245985 PMID:30796460 PMID:30980806 PMID:31298478 PMID:31364909 PMID:33651226 PMID:34520753 PMID:35413383 PMID:36030031 PMID:36646296 PMID:37148176 PMID:37692514 PMID:38242296 PMID:38450909 More...
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|
NCBI chr13:85,460,312...85,639,959
Ensembl chr13:85,462,840...85,640,033
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|
G
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Atf6b
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activating transcription factor 6 beta
|
multiple interactions
|
EXP
|
4-phenylbutyric acid inhibits the reaction [Methamphetamine results in increased expression of ATF6B protein]
|
CTD |
PMID:34214594 |
|
NCBI chr20:4,095,534...4,103,534
Ensembl chr20:4,095,534...4,106,032
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|
G
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Atg12
|
autophagy related 12
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multiple interactions
|
ISO
|
4-phenylbutyric acid inhibits the reaction [cyanoginosin LR results in increased expression of ATG12 mRNA]; 4-phenylbutyric acid inhibits the reaction [cyanoginosin LR results in increased expression of ATG12 protein]
|
CTD |
PMID:34175825 |
|
NCBI chr18:41,638,841...41,649,311
Ensembl chr18:41,635,835...41,649,261
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|
G
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Atg3
|
autophagy related 3
|
multiple interactions
|
ISO
|
4-phenylbutyric acid inhibits the reaction [Cantharidin results in increased expression of ATG3 protein]
|
CTD |
PMID:35398186 |
|
NCBI chr11:69,130,948...69,159,280
Ensembl chr11:69,121,952...69,159,280
|
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G
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Atg4b
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autophagy related 4B, cysteine peptidase
|
decreases expression multiple interactions
|
ISO
|
4-phenylbutyric acid results in decreased expression of ATG4B protein 4-phenylbutyric acid inhibits the reaction [Curcumin results in decreased expression of ATG4B protein]
|
CTD |
PMID:36640941 |
|
NCBI chr 9:101,729,772...101,761,456
Ensembl chr 9:101,726,782...101,761,622
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|
G
|
Atg5
|
autophagy related 5
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multiple interactions
|
ISO EXP
|
4-phenylbutyric acid inhibits the reaction [cyanoginosin LR results in increased expression of ATG5 mRNA]; 4-phenylbutyric acid inhibits the reaction [cyanoginosin LR results in increased expression of ATG5 protein] 4-phenylbutyric acid inhibits the reaction [Lipopolysaccharides results in increased expression of ATG5 mRNA]; 4-phenylbutyric acid inhibits the reaction [Lipopolysaccharides results in increased expression of ATG5 protein]
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CTD |
PMID:34175825 PMID:37654027 |
|
NCBI chr20:49,380,835...49,471,826
Ensembl chr20:49,380,813...49,471,821
|
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G
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Bax
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BCL2 associated X, apoptosis regulator
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decreases expression multiple interactions increases expression
|
ISO EXP
|
4-phenylbutyric acid results in decreased expression of BAX protein 4-phenylbutyric acid inhibits the reaction [alpha-Chlorohydrin results in increased expression of BAX protein]; 4-phenylbutyric acid inhibits the reaction [Methamphetamine results in increased expression of BAX protein]; 4-phenylbutyric acid inhibits the reaction [Oxygen deficiency results in increased expression of BAX protein]; 4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of BAX protein] 4-phenylbutyric acid inhibits the reaction [Ficusin results in increased expression of BAX protein]; 4-phenylbutyric acid inhibits the reaction [hydroquinone results in increased expression of BAX protein]; 4-phenylbutyric acid inhibits the reaction [Silver Compounds results in increased expression of BAX protein]; 4-phenylbutyric acid inhibits the reaction [tris(1,3-dichloro-2-propyl)phosphate results in increased expression of BAX protein]; 4-phenylbutyric acid promotes the reaction [Acetylcysteine inhibits the reaction [tris(1,3-dichloro-2-propyl)phosphate results in increased expression of BAX protein]]; Acetylcysteine promotes the reaction [4-phenylbutyric acid inhibits the reaction [tris(1,3-dichloro-2-propyl)phosphate results in increased expression of BAX protein]] 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [4-phenylbutyric acid inhibits the reaction [4-methyl-2,4-bis(4-hydroxyphenyl)pent-1-ene results in increased expression of BAX protein]]; 4-phenylbutyric acid inhibits the reaction [dibromoacetonitrile results in increased expression of BAX protein] 4-phenylbutyric acid results in increased expression of BAX protein
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CTD |
PMID:25450231 PMID:27816613 PMID:29306025 PMID:30980806 PMID:31364909 PMID:33651226 PMID:33771661 PMID:34214594 PMID:37148176 PMID:38065397 More...
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|
NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429
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G
|
Bbc3
|
Bcl-2 binding component 3
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multiple interactions
|
EXP
|
4-phenylbutyric acid inhibits the reaction [Methamphetamine results in increased expression of BBC3 protein]
|
CTD |
PMID:34214594 |
|
NCBI chr 1:86,141,450...86,150,666
Ensembl chr 1:86,141,603...86,150,666
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G
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Bcl2
|
BCL2, apoptosis regulator
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multiple interactions increases expression
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ISO EXP
|
4-phenylbutyric acid inhibits the reaction [Silver Compounds results in decreased expression of BCL2 protein]; 4-phenylbutyric acid inhibits the reaction [tris(1,3-dichloro-2-propyl)phosphate results in decreased expression of BCL2 protein]; 4-phenylbutyric acid promotes the reaction [Acetylcysteine inhibits the reaction [tris(1,3-dichloro-2-propyl)phosphate results in decreased expression of BCL2 protein]]; Acetylcysteine promotes the reaction [4-phenylbutyric acid inhibits the reaction [tris(1,3-dichloro-2-propyl)phosphate results in decreased expression of BCL2 protein]] 4-phenylbutyric acid inhibits the reaction [alpha-Chlorohydrin results in decreased expression of BCL2 protein]; 4-phenylbutyric acid inhibits the reaction [Methamphetamine results in decreased expression of BCL2 protein] 4-phenylbutyric acid results in increased expression of BCL2 protein 4-phenylbutyric acid inhibits the reaction [dibromoacetonitrile results in decreased expression of BCL2 protein]; [4-phenylbutyric acid co-treated with Ficusin] results in increased expression of BCL2 protein
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CTD |
PMID:27816613 PMID:29306025 PMID:33651226 PMID:34214594 PMID:38065397 PMID:39299507 More...
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NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900
|
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G
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Bcl2l11
|
Bcl2-like 11
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multiple interactions
|
EXP
|
4-phenylbutyric acid inhibits the reaction [Methamphetamine results in increased expression of BCL2L11 protein]
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CTD |
PMID:34214594 |
|
NCBI chr 3:135,820,042...135,857,330
Ensembl chr 3:135,817,562...135,960,695
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G
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Bcl6
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BCL6, transcription repressor
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increases expression
|
ISO
|
4-phenylbutyric acid results in increased expression of BCL6 mRNA
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CTD |
PMID:14583596 |
|
NCBI chr11:90,358,753...90,382,049
Ensembl chr11:90,358,753...90,382,047
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G
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Becn1
|
beclin 1
|
multiple interactions
|
ISO EXP
|
4-phenylbutyric acid inhibits the reaction [Cadmium Chloride results in increased expression of BECN1 protein]; 4-phenylbutyric acid inhibits the reaction [Cantharidin results in increased expression of BECN1 protein]; 4-phenylbutyric acid inhibits the reaction [Ethylmercury Compounds results in increased expression of BECN1 protein]; 4-phenylbutyric acid inhibits the reaction [ochratoxin A results in increased expression of BECN1 protein]; 4-phenylbutyric acid inhibits the reaction [Particulate Matter results in increased expression of BECN1 protein] 4-phenylbutyric acid inhibits the reaction [Lipopolysaccharides results in increased expression of BECN1 mRNA]; 4-phenylbutyric acid inhibits the reaction [Lipopolysaccharides results in increased expression of BECN1 protein] 4-phenylbutyric acid inhibits the reaction [dibromoacetonitrile results in increased expression of BECN1 protein]
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CTD |
PMID:27511942 PMID:33127495 PMID:35398186 PMID:36058351 PMID:36700298 PMID:37654027 PMID:38065397 More...
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|
NCBI chr10:86,731,649...86,747,002
Ensembl chr10:86,731,650...86,747,002
|
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G
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Birc5
|
baculoviral IAP repeat-containing 5
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decreases expression
|
ISO
|
4-phenylbutyric acid results in decreased expression of BIRC5 mRNA
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CTD |
PMID:30481203 |
|
NCBI chr10:103,567,369...103,580,069
Ensembl chr10:103,572,080...103,582,155
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G
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Bnip3
|
BCL2 interacting protein 3
|
multiple interactions
|
ISO
|
4-phenylbutyric acid inhibits the reaction [Cadmium Chloride results in increased expression of BNIP3 protein]
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CTD |
PMID:33127495 |
|
NCBI chr 1:203,137,778...203,154,962
Ensembl chr 1:203,137,778...203,154,962
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G
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Camkk2
|
calcium/calmodulin-dependent protein kinase kinase 2
|
multiple interactions
|
ISO
|
4-phenylbutyric acid inhibits the reaction [alpha-Chlorohydrin results in increased expression of CAMKK2 protein]
|
CTD |
PMID:33651226 |
|
NCBI chr12:39,451,828...39,505,719
Ensembl chr12:39,451,834...39,514,964
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G
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Capn2
|
calpain 2
|
multiple interactions
|
ISO
|
4-phenylbutyric acid inhibits the reaction [honokiol results in increased expression of CAPN2 protein]
|
CTD |
PMID:34973135 |
|
NCBI chr13:96,681,902...96,732,625
Ensembl chr13:96,681,848...96,732,625
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G
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Cars1
|
cysteinyl-tRNA synthetase 1
|
decreases expression increases expression
|
ISO
|
4-phenylbutyric acid results in decreased expression of CARS1 mRNA 4-phenylbutyric acid results in increased expression of CARS1 mRNA
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CTD |
PMID:14583596 |
|
NCBI chr 1:208,183,092...208,225,425
Ensembl chr 1:208,182,788...208,225,407
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G
|
Casp1
|
caspase 1
|
multiple interactions
|
ISO EXP
|
4-phenylbutyric acid inhibits the reaction [Cadmium Chloride results in increased cleavage of CASP1 protein]; 4-phenylbutyric acid inhibits the reaction [Cadmium Chloride results in increased expression of CASP1 mRNA]; 4-phenylbutyric acid inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of CASP1 protein] 4-phenylbutyric acid inhibits the reaction [7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased cleavage of CASP1 protein]; 4-phenylbutyric acid inhibits the reaction [hydroquinone results in increased cleavage of CASP1 protein] 4-phenylbutyric acid inhibits the reaction [Lipopolysaccharides results in increased activity of CASP1 protein]
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CTD |
PMID:30796460 PMID:35297523 PMID:36646296 PMID:37654027 PMID:37692514 |
|
NCBI chr 8:10,746,338...10,882,295
Ensembl chr 8:10,746,333...10,882,275
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G
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Casp12
|
caspase 12
|
multiple interactions
|
ISO EXP
|
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [4-phenylbutyric acid inhibits the reaction [4-methyl-2,4-bis(4-hydroxyphenyl)pent-1-ene results in decreased expression of CASP12 protein]]; 4-phenylbutyric acid inhibits the reaction [Arecoline results in increased cleavage of CASP12 protein]; 4-phenylbutyric acid inhibits the reaction [Arsenic Trioxide results in increased expression of CASP12 protein modified form]; 4-phenylbutyric acid inhibits the reaction [Lipopolysaccharides results in increased expression of CASP12 protein]; 4-phenylbutyric acid inhibits the reaction [Rotenone results in increased activity of CASP12 protein] 4-phenylbutyric acid inhibits the reaction [alpha-Chlorohydrin results in increased expression of and results in increased cleavage of CASP12 protein]; 4-phenylbutyric acid inhibits the reaction [hydroquinone results in increased expression of CASP12 protein]; 4-phenylbutyric acid inhibits the reaction [Lipopolysaccharides results in increased expression of CASP12 protein]; 4-phenylbutyric acid results in increased expression of and results in decreased cleavage of CASP12 protein 4-phenylbutyric acid inhibits the reaction [4-methyl-2,4-bis(4-hydroxyphenyl)pent-1-ene results in increased degradation of CASP12 protein]; 4-phenylbutyric acid inhibits the reaction [alpha-Chlorohydrin results in increased expression of and results in increased cleavage of CASP12 protein]
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CTD |
PMID:17459145 PMID:27638049 PMID:28245985 PMID:33651226 PMID:33771661 PMID:33922211 PMID:36646296 PMID:38450909 More...
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NCBI chr 8:10,927,188...10,954,442
Ensembl chr 8:10,926,994...10,954,442
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G
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Casp3
|
caspase 3
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multiple interactions decreases expression
|
ISO EXP
|
4-phenylbutyric acid inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased cleavage of CASP3 protein]; 4-phenylbutyric acid inhibits the reaction [Cyclosporine results in increased cleavage of CASP3 protein]; 4-phenylbutyric acid inhibits the reaction [Ficusin results in increased activity of CASP3 protein]; 4-phenylbutyric acid inhibits the reaction [Potassium Dichromate results in increased expression of CASP3 protein modified form]; 4-phenylbutyric acid inhibits the reaction [Sertraline results in increased activity of CASP3 protein]; 4-phenylbutyric acid inhibits the reaction [SFTPC protein mutant form results in increased cleavage of CASP3 protein]; 4-phenylbutyric acid inhibits the reaction [Silver Compounds results in increased expression of CASP3 protein modified form]; 4-phenylbutyric acid inhibits the reaction [thymoquinone results in increased cleavage of CASP3 protein]; 4-phenylbutyric acid inhibits the reaction [usnic acid results in increased activity of CASP3 protein] 4-phenylbutyric acid results in decreased expression of CASP3 protein 4-phenylbutyric acid inhibits the reaction [4-methyl-2,4-bis(4-hydroxyphenyl)pent-1-ene results in increased activity of and results in increased cleavage of CASP3 protein]; 4-phenylbutyric acid inhibits the reaction [alpha-Chlorohydrin results in increased cleavage of CASP3 protein]; 4-phenylbutyric acid inhibits the reaction [cobaltous chloride results in increased activity of CASP3 protein]; 4-phenylbutyric acid inhibits the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; 4-phenylbutyric acid inhibits the reaction [Oxygen deficiency results in increased expression of CASP3 protein]; 4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein] 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [4-phenylbutyric acid inhibits the reaction [4-methyl-2,4-bis(4-hydroxyphenyl)pent-1-ene results in increased cleavage of CASP3 protein]]; 4-phenylbutyric acid inhibits the reaction [4-methyl-2,4-bis(4-hydroxyphenyl)pent-1-ene results in increased cleavage of CASP3 protein]; 4-phenylbutyric acid inhibits the reaction [Arecoline results in increased cleavage of CASP3 protein]; 4-phenylbutyric acid inhibits the reaction [Arsenic Trioxide results in increased expression of CASP3 protein modified form]; 4-phenylbutyric acid inhibits the reaction [Bilirubin results in increased cleavage of CASP3 protein]; 4-phenylbutyric acid inhibits the reaction [Ficusin results in increased expression of CASP3 protein]; 4-phenylbutyric acid inhibits the reaction [Mercuric Chloride results in increased expression of CASP3 protein modified form]; 4-phenylbutyric acid inhibits the reaction [Tunicamycin results in increased expression of CASP3 protein modified form]
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CTD |
PMID:21804221 PMID:24865413 PMID:25450231 PMID:25870318 PMID:27578021 PMID:27638049 PMID:27638906 PMID:29306025 PMID:29981725 PMID:30980806 PMID:31364909 PMID:32407927 PMID:32569804 PMID:32879258 PMID:33651226 PMID:33771661 PMID:33922211 PMID:34214594 PMID:35033536 PMID:38450909 PMID:39299507 More...
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NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
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G
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Casp7
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caspase 7
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multiple interactions
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ISO EXP
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4-phenylbutyric acid inhibits the reaction [Sertraline results in increased activity of CASP7 protein]; 4-phenylbutyric acid inhibits the reaction [usnic acid results in increased activity of CASP7 protein] 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [4-phenylbutyric acid inhibits the reaction [4-methyl-2,4-bis(4-hydroxyphenyl)pent-1-ene results in increased cleavage of CASP7 protein]]; 4-phenylbutyric acid inhibits the reaction [4-methyl-2,4-bis(4-hydroxyphenyl)pent-1-ene results in increased cleavage of CASP7 protein]
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CTD |
PMID:24865413 PMID:25870318 PMID:33771661 PMID:33922211 |
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NCBI chr 1:265,442,647...265,481,938
Ensembl chr 1:265,442,676...265,482,512
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G
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Casp8
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caspase 8
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multiple interactions
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ISO
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4-phenylbutyric acid inhibits the reaction [Ficusin results in increased activity of CASP8 protein]
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CTD |
PMID:31364909 |
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NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:67,758,033...67,806,699
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G
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Casp9
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caspase 9
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multiple interactions
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ISO EXP
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4-phenylbutyric acid inhibits the reaction [alpha-Chlorohydrin results in increased cleavage of CASP9 protein]; 4-phenylbutyric acid inhibits the reaction [Potassium Dichromate results in increased expression of CASP9 protein modified form]; 4-phenylbutyric acid inhibits the reaction [Silver Compounds results in increased expression of CASP9 protein modified form] 4-phenylbutyric acid inhibits the reaction [Arecoline results in increased cleavage of CASP9 protein]
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CTD |
PMID:29306025 PMID:32569804 PMID:33651226 PMID:38450909 |
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Ensembl chr 5:159,391,188...159,409,648
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G
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Cat
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catalase
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multiple interactions
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ISO
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4-phenylbutyric acid inhibits the reaction [Ficusin results in decreased activity of CAT protein]
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CTD |
PMID:39299507 |
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NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526
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G
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Ccl2
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C-C motif chemokine ligand 2
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decreases expression multiple interactions
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ISO
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4-phenylbutyric acid results in decreased expression of CCL2 mRNA 4-phenylbutyric acid inhibits the reaction [3-acetyldeoxynivalenol results in increased expression of and results in increased secretion of CCL2 protein]; 4-phenylbutyric acid inhibits the reaction [3-acetyldeoxynivalenol results in increased expression of CCL2 mRNA]
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CTD |
PMID:28698385 PMID:35413383 |
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NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,503,077...67,504,875
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G
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Ccnb1
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cyclin B1
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multiple interactions
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ISO
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4-phenylbutyric acid inhibits the reaction [ochratoxin A results in decreased expression of CCNB1 protein]
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CTD |
PMID:36058351 |
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NCBI chr 2:33,646,252...33,655,225
Ensembl chr 2:33,646,252...33,655,225
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G
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Cd36
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CD36 molecule
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multiple interactions
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ISO
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4-phenylbutyric acid promotes the reaction [[2,3,5-trichloro-6-phenyl-(1,4)benzoquinone co-treated with malondialdehyde-low density lipoprotein, human] results in increased expression of CD36 mRNA]
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CTD |
PMID:32434321 |
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NCBI chr 4:18,209,088...18,302,142
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G
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Cdc25c
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cell division cycle 25C
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multiple interactions
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ISO
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4-phenylbutyric acid inhibits the reaction [ochratoxin A results in decreased expression of CDC25C protein]
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CTD |
PMID:36058351 |
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NCBI chr18:26,608,483...26,630,292
Ensembl chr18:26,609,959...26,630,292
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G
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Cdk1
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cyclin-dependent kinase 1
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multiple interactions
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ISO
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4-phenylbutyric acid inhibits the reaction [ochratoxin A results in decreased expression of CDK1 protein]
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CTD |
PMID:36058351 |
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NCBI chr20:19,265,252...19,280,456
Ensembl chr20:19,265,289...19,280,455
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G
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Cdkn1a
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cyclin-dependent kinase inhibitor 1A
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multiple interactions increases expression
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ISO
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[4-phenylbutyric acid co-treated with decitabine] results in increased expression of CDKN1A mRNA 4-phenylbutyric acid results in increased expression of CDKN1A protein
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CTD |
PMID:17210717 PMID:23770000 |
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NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969
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G
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Cdkn2a
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cyclin-dependent kinase inhibitor 2A
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multiple interactions
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ISO
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[4-phenylbutyric acid co-treated with decitabine] results in increased expression of CDKN2A mRNA
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CTD |
PMID:17210717 |
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NCBI chr 5:109,100,763...109,114,448
Ensembl chr 5:109,100,772...109,119,248
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G
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Cebpb
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CCAAT/enhancer binding protein beta
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multiple interactions
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ISO
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4-phenylbutyric acid inhibits the reaction [honokiol results in decreased activity of CEBPB protein]
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CTD |
PMID:34973135 |
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NCBI chr 3:176,817,005...176,818,436
Ensembl chr 3:176,816,859...176,838,072
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G
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Cftr
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CF transmembrane conductance regulator
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multiple interactions increases activity
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ISO
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4-phenylbutyric acid results in increased activity of and affects the localization of CFTR protein mutant form; 4-phenylbutyric acid results in increased stability of and affects the localization of CFTR protein 4-phenylbutyric acid results in increased activity of CFTR protein mutant form
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CTD |
PMID:14583596 PMID:15191910 PMID:15880796 |
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NCBI chr 4:47,422,084...47,694,646
Ensembl chr 4:47,526,735...47,694,643
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G
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Cidec
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cell death-inducing DFFA-like effector c
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multiple interactions
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ISO
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4-phenylbutyric acid inhibits the reaction [Amiodarone results in increased expression of CIDEC mRNA]
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CTD |
PMID:28962527 |
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NCBI chr 4:148,124,924...148,137,806
Ensembl chr 4:148,124,925...148,137,806
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G
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Cited2
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Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
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decreases expression
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ISO
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4-phenylbutyric acid results in decreased expression of CITED2 mRNA
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CTD |
PMID:14583596 |
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NCBI chr 1:14,132,303...14,134,746
Ensembl chr 1:14,103,457...14,134,782
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G
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Cldn1
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claudin 1
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decreases expression
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ISO
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4-phenylbutyric acid results in decreased expression of CLDN1 mRNA
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CTD |
PMID:14583596 |
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NCBI chr11:87,926,376...87,941,533
Ensembl chr11:87,926,337...87,941,529
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G
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Cldn11
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claudin 11
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multiple interactions
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ISO
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4-phenylbutyric acid inhibits the reaction [Busulfan results in decreased expression of CLDN11 protein]
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CTD |
PMID:35533795 |
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NCBI chr 2:114,136,234...114,149,539
Ensembl chr 2:114,136,234...114,149,539
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G
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Cmss1
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cms1 ribosomal small subunit homolog
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decreases expression
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ISO
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4-phenylbutyric acid results in decreased expression of CMSS1 mRNA
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CTD |
PMID:14583596 |
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NCBI chr11:56,403,620...56,701,751
Ensembl chr11:56,403,499...56,701,755
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G
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Cnih4
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cornichon family member 4
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decreases expression
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ISO
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4-phenylbutyric acid results in decreased expression of CNIH4 mRNA
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CTD |
PMID:14583596 |
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NCBI chr13:95,442,054...95,458,163
Ensembl chr13:95,442,054...95,459,590
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G
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Cnot2
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CCR4-NOT transcription complex, subunit 2
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decreases expression
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ISO
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4-phenylbutyric acid results in decreased expression of CNOT2 mRNA
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CTD |
PMID:14583596 |
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NCBI chr 7:54,016,447...54,117,511
Ensembl chr 7:54,016,447...54,107,960
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G
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Col10a1
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collagen type X alpha 1 chain
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multiple interactions
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EXP
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4-phenylbutyric acid inhibits the reaction [6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide results in decreased expression of COL10A1 protein]
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CTD |
PMID:29653943 |
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NCBI chr20:39,737,536...39,744,518
Ensembl chr20:39,716,822...39,751,440
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G
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Col5a1
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collagen type V alpha 1 chain
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increases expression
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ISO
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4-phenylbutyric acid results in increased expression of COL5A1 mRNA
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CTD |
PMID:14583596 |
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NCBI chr 3:31,606,475...31,755,097
Ensembl chr 3:31,606,486...31,753,020
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G
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Cox4i1
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cytochrome c oxidase subunit 4i1
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multiple interactions
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ISO
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4-phenylbutyric acid inhibits the reaction [Potassium Dichromate results in decreased expression of COX4I1 protein]
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CTD |
PMID:36473502 |
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NCBI chr19:65,630,383...65,636,623
Ensembl chr19:65,630,432...65,636,624
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G
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Csde1
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cold shock domain containing E1
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decreases expression
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ISO
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4-phenylbutyric acid results in decreased expression of CSDE1 mRNA
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CTD |
PMID:14583596 |
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NCBI chr 2:193,234,546...193,271,301
Ensembl chr 2:193,243,526...193,271,301
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G
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Csf1
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colony stimulating factor 1
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multiple interactions
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ISO
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4-phenylbutyric acid inhibits the reaction [3-acetyldeoxynivalenol results in increased expression of CSF1 mRNA]
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CTD |
PMID:35413383 |
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NCBI chr 2:198,065,400...198,084,774
Ensembl chr 2:198,065,405...198,084,468
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G
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Csf2
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colony stimulating factor 2
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multiple interactions
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ISO
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4-phenylbutyric acid inhibits the reaction [3-acetyldeoxynivalenol results in increased expression of and results in increased secretion of CSF2 protein]
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CTD |
PMID:35413383 |
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NCBI chr10:38,887,692...38,889,673
Ensembl chr10:38,887,692...38,890,031
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G
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Csf3
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colony stimulating factor 3
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multiple interactions
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ISO
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4-phenylbutyric acid inhibits the reaction [3-acetyldeoxynivalenol results in increased expression of CSF3 mRNA]
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CTD |
PMID:35413383 |
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NCBI chr10:84,157,485...84,159,860
Ensembl chr10:84,157,211...84,159,860
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G
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Cspg5
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chondroitin sulfate proteoglycan 5
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increases expression
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ISO
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4-phenylbutyric acid results in increased expression of CSPG5 mRNA
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CTD |
PMID:14583596 |
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NCBI chr 8:119,098,932...119,113,191
Ensembl chr 8:119,098,925...119,143,907
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G
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Cst3
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cystatin C
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multiple interactions
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ISO
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4-phenylbutyric acid inhibits the reaction [alpha-Chlorohydrin results in increased expression of and affects the localization of CST3 protein]
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CTD |
PMID:33651226 |
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NCBI chr 3:156,790,061...156,794,116
Ensembl chr 3:156,790,079...156,793,937
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G
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Ctsd
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cathepsin D
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multiple interactions
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ISO
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4-phenylbutyric acid inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased cleavage of CTSD protein]; 4-phenylbutyric acid inhibits the reaction [SFTPC protein mutant form results in increased cleavage of CTSD protein]
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CTD |
PMID:27638906 |
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NCBI chr 1:206,956,945...206,968,821
Ensembl chr 1:206,956,944...206,968,821
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G
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Cycs
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cytochrome c, somatic
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multiple interactions
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ISO
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4-phenylbutyric acid inhibits the reaction [SC-66 compound results in increased expression of CYCS protein]; 4-phenylbutyric acid inhibits the reaction [Silver Compounds results in increased expression of CYCS protein]
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CTD |
PMID:29306025 PMID:37741534 |
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NCBI chr 4:80,982,667...80,984,767
Ensembl chr 4:80,982,668...80,984,816 Ensembl chr18:80,982,668...80,984,816
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G
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Ddit3
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DNA-damage inducible transcript 3
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multiple interactions decreases expression decreases phosphorylation
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ISO EXP
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4-phenylbutyric acid inhibits the reaction [Acrylamide results in increased expression of DDIT3 mRNA]; 4-phenylbutyric acid inhibits the reaction [alpha-Chlorohydrin results in increased phosphorylation of DDIT3 protein]; 4-phenylbutyric acid inhibits the reaction [Amiodarone results in increased expression of DDIT3 mRNA]; 4-phenylbutyric acid inhibits the reaction [Amiodarone results in increased expression of DDIT3 protein]; 4-phenylbutyric acid inhibits the reaction [Cantharidin results in increased expression of DDIT3 protein]; 4-phenylbutyric acid inhibits the reaction [Cisplatin results in increased expression of DDIT3 protein]; 4-phenylbutyric acid inhibits the reaction [Cyclosporine results in increased expression of and affects the localization of DDIT3 protein]; 4-phenylbutyric acid inhibits the reaction [discretamine results in increased expression of DDIT3 protein]; 4-phenylbutyric acid inhibits the reaction [Ficusin results in increased expression of DDIT3 mRNA]; 4-phenylbutyric acid inhibits the reaction [flavokawain B results in increased expression of DDIT3 protein]; 4-phenylbutyric acid inhibits the reaction [fumonisin B1 results in increased expression of DDIT3 protein]; 4-phenylbutyric acid inhibits the reaction [hydroquinone results in increased expression of and affects the localization of DDIT3 protein]; 4-phenylbutyric acid inhibits the reaction [hydroquinone results in increased expression of DDIT3 protein]; 4-phenylbutyric acid inhibits the reaction [Leflunomide results in increased expression of DDIT3 protein]; 4-phenylbutyric acid inhibits the reaction [Lipopolysaccharides results in increased expression of DDIT3 protein]; 4-phenylbutyric acid inhibits the reaction [nefazodone results in increased expression of DDIT3 protein]; 4-phenylbutyric acid inhibits the reaction [perhexiline maleate results in increased expression of DDIT3 protein]; 4-phenylbutyric acid inhibits the reaction [Pyrazinamide results in increased expression of DDIT3 protein]; 4-phenylbutyric acid inhibits the reaction [Rifampin results in increased expression of DDIT3 mRNA]; 4-phenylbutyric acid inhibits the reaction [SC-66 compound results in increased expression of DDIT3 protein]; 4-phenylbutyric acid inhibits the reaction [Sertraline results in increased expression of DDIT3 protein]; 4-phenylbutyric acid inhibits the reaction [thymoquinone results in increased expression of DDIT3 protein]; 4-phenylbutyric acid inhibits the reaction [tris(1,3-dichloro-2-propyl)phosphate results in increased expression of DDIT3 protein]; 4-phenylbutyric acid promotes the reaction [Acetylcysteine inhibits the reaction [tris(1,3-dichloro-2-propyl)phosphate results in increased expression of DDIT3 protein]]; Acetylcysteine promotes the reaction [4-phenylbutyric acid inhibits the reaction [tris(1,3-dichloro-2-propyl)phosphate results in increased expression of DDIT3 protein]] 4-phenylbutyric acid results in decreased expression of DDIT3 protein 4-phenylbutyric acid inhibits the reaction [4-methyl-2,4-bis(4-hydroxyphenyl)pent-1-ene results in increased expression of DDIT3 protein]; 4-phenylbutyric acid inhibits the reaction [6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide results in increased expression of DDIT3 mRNA]; 4-phenylbutyric acid inhibits the reaction [6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide results in increased expression of DDIT3 protein]; 4-phenylbutyric acid inhibits the reaction [[Air Pollutants results in increased abundance of Particulate Matter] which results in increased expression of DDIT3 protein]; 4-phenylbutyric acid inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of DDIT3 mRNA]; 4-phenylbutyric acid inhibits the reaction [Acrylamide promotes the reaction [elaidic acid results in increased expression of DDIT3 protein]]; 4-phenylbutyric acid inhibits the reaction [alpha-Chlorohydrin results in increased phosphorylation of DDIT3 protein]; 4-phenylbutyric acid inhibits the reaction [Chlormequat results in increased expression of DDIT3 protein]; 4-phenylbutyric acid inhibits the reaction [Dibutyl Phthalate results in increased expression of DDIT3 protein]; 4-phenylbutyric acid inhibits the reaction [elaidic acid promotes the reaction [Acrylamide results in increased expression of DDIT3 protein]]; 4-phenylbutyric acid inhibits the reaction [Lipopolysaccharides results in increased expression of DDIT3 protein]; 4-phenylbutyric acid inhibits the reaction [Methamphetamine results in increased expression of DDIT3 protein]; 4-phenylbutyric acid inhibits the reaction [Oxygen deficiency results in increased expression of DDIT3 protein]; 4-phenylbutyric acid inhibits the reaction [Pyrazinamide results in increased expression of DDIT3 protein]; 4-phenylbutyric acid inhibits the reaction [SIRT1 protein affects the expression of DDIT3 mRNA]; 4-phenylbutyric acid inhibits the reaction [SIRT1 protein affects the expression of DDIT3 protein]; 4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of DDIT3 protein]; 4-phenylbutyric acid inhibits the reaction [tetrachlorobenzoquinone results in increased expression of DDIT3 protein]; 4-phenylbutyric acid inhibits the reaction [Thapsigargin results in increased expression of DDIT3 protein]; 4-phenylbutyric acid inhibits the reaction [Tunicamycin results in increased expression of DDIT3 protein] 4-phenylbutyric acid inhibits the reaction [3-acetyldeoxynivalenol results in increased expression of DDIT3 mRNA]; 4-phenylbutyric acid inhibits the reaction [4-methyl-2,4-bis(4-hydroxyphenyl)pent-1-ene results in increased expression of DDIT3 protein]; 4-phenylbutyric acid inhibits the reaction [anandamide results in increased expression of DDIT3 protein]; 4-phenylbutyric acid inhibits the reaction [Arecoline results in increased phosphorylation of DDIT3 protein]; 4-phenylbutyric acid inhibits the reaction [Arsenic Trioxide results in increased expression of DDIT3 protein]; 4-phenylbutyric acid inhibits the reaction [Bilirubin results in increased expression of DDIT3 mRNA]; 4-phenylbutyric acid inhibits the reaction [Busulfan results in increased expression of DDIT3 protein]; 4-phenylbutyric acid inhibits the reaction [Cadmium Chloride results in increased expression of DDIT3 mRNA]; 4-phenylbutyric acid inhibits the reaction [Cadmium Chloride results in increased expression of DDIT3 protein]; 4-phenylbutyric acid inhibits the reaction [dibromoacetonitrile results in increased expression of DDIT3 protein]; 4-phenylbutyric acid inhibits the reaction [Dibutyl Phthalate results in increased expression of DDIT3 protein]; 4-phenylbutyric acid inhibits the reaction [Ficusin results in increased expression of DDIT3 protein]; 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of DDIT3 mRNA]; 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of DDIT3 protein]; 4-phenylbutyric acid inhibits the reaction [Hydrogen Peroxide results in increased expression of DDIT3 mRNA]; 4-phenylbutyric acid inhibits the reaction [Hydrogen Peroxide results in increased expression of DDIT3 protein]; 4-phenylbutyric acid inhibits the reaction [Lipopolysaccharides results in increased expression of DDIT3 protein]; 4-phenylbutyric acid inhibits the reaction [Mercuric Chloride results in increased expression of DDIT3 protein]; 4-phenylbutyric acid inhibits the reaction [perfluorooctanoic acid results in increased expression of DDIT3 mRNA]; 4-phenylbutyric acid inhibits the reaction [perfluorooctanoic acid results in increased expression of DDIT3 protein]; 4-phenylbutyric acid inhibits the reaction [Sunitinib results in increased expression of DDIT3 mRNA]; 4-phenylbutyric acid inhibits the reaction [titanium dioxide results in increased expression of DDIT3 mRNA]; 4-phenylbutyric acid inhibits the reaction [titanium dioxide results in increased expression of DDIT3 protein]; 4-phenylbutyric acid inhibits the reaction [Tunicamycin results in increased expression of DDIT3 mRNA]; 4-phenylbutyric acid inhibits the reaction [Tunicamycin results in increased expression of DDIT3 protein]; 4-phenylbutyric acid promotes the reaction [Palmitic Acid results in increased expression of DDIT3 mRNA] 4-phenylbutyric acid results in decreased phosphorylation of DDIT3 protein
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CTD |
PMID:24053669 PMID:24865413 PMID:25295624 PMID:25450231 PMID:26513129 PMID:26804720 PMID:27470132 PMID:27484784 PMID:27578021 PMID:27613715 PMID:27634458 PMID:27638049 PMID:27816613 PMID:28063906 PMID:28245985 PMID:28698385 PMID:28844859 PMID:28988120 PMID:29653943 PMID:29981725 PMID:30025493 PMID:30602124 PMID:30980806 PMID:31298478 PMID:31364909 PMID:31891755 PMID:32407927 PMID:32578922 PMID:32590070 PMID:32879258 PMID:33309543 PMID:33651226 PMID:33677747 PMID:33771661 PMID:33922211 PMID:34214594 PMID:34533242 PMID:34958886 PMID:35033536 PMID:35398186 PMID:35413383 PMID:35533795 PMID:36030031 PMID:36646296 PMID:37654027 PMID:37741534 PMID:38065397 PMID:38242296 PMID:38450909 PMID:38740238 PMID:39299507 PMID:39442789 PMID:39613054 More...
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NCBI chr 7:65,001,695...65,006,517
Ensembl chr 7:65,005,501...65,006,509
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G
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Ddx55
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DEAD-box helicase 55
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decreases expression
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ISO
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4-phenylbutyric acid results in decreased expression of DDX55 mRNA
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CTD |
PMID:14583596 |
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NCBI chr12:37,695,444...37,711,198
Ensembl chr12:37,695,444...37,711,198
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G
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Derl1
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derlin 1
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multiple interactions
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EXP
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4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of DERL1 protein]
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CTD |
PMID:30980806 |
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NCBI chr 7:91,293,963...91,316,639
Ensembl chr 7:91,258,382...91,316,678
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G
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Dgat1
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diacylglycerol O-acyltransferase 1
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multiple interactions
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ISO
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4-phenylbutyric acid inhibits the reaction [bisphenol A results in increased expression of DGAT1 mRNA]
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CTD |
PMID:36670177 |
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NCBI chr 7:110,104,514...110,119,091
Ensembl chr 7:110,098,906...110,115,016
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G
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Dnajb9
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DnaJ heat shock protein family (Hsp40) member B9
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multiple interactions decreases expression
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ISO
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4-phenylbutyric acid inhibits the reaction [Amiodarone results in increased expression of DNAJB9 mRNA] 4-phenylbutyric acid results in decreased expression of DNAJB9 mRNA
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CTD |
PMID:28698385 PMID:28962527 |
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NCBI chr 6:66,997,842...67,007,371
Ensembl chr 6:66,997,842...67,009,344
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G
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Dnm1l
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dynamin 1-like
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increases phosphorylation multiple interactions
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ISO EXP
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4-phenylbutyric acid results in increased phosphorylation of DNM1L protein 4-phenylbutyric acid inhibits the reaction [alpha-Chlorohydrin results in increased expression of and affects the localization of DNM1L protein]; 4-phenylbutyric acid inhibits the reaction [alpha-Chlorohydrin results in increased phosphorylation of DNM1L protein] 4-phenylbutyric acid inhibits the reaction [alpha-Chlorohydrin results in increased expression of and results in increased phosphorylation of DNM1L protein] 4-phenylbutyric acid inhibits the reaction [Ficusin results in increased expression of DNM1L protein]
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CTD |
PMID:33651226 PMID:39299507 |
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NCBI chr11:98,084,049...98,135,663
Ensembl chr11:98,085,397...98,137,420
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G
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Edem1
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ER degradation enhancing alpha-mannosidase like protein 1
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multiple interactions decreases expression
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ISO
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4-phenylbutyric acid promotes the reaction [LEPR gene mutant form results in increased expression of EDEM1 mRNA] 4-phenylbutyric acid results in decreased expression of EDEM1 mRNA
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CTD |
PMID:23274897 PMID:28698385 |
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NCBI chr 4:143,350,989...143,385,693
Ensembl chr 4:143,353,624...143,388,060
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G
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Eef1e1
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eukaryotic translation elongation factor 1 epsilon 1
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decreases expression
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ISO
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4-phenylbutyric acid results in decreased expression of EEF1E1 mRNA
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CTD |
PMID:14583596 |
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NCBI chr17:26,354,247...26,364,953
Ensembl chr17:26,354,228...26,370,687
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G
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Eftud2
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elongation factor Tu GTP binding domain containing 2
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decreases expression
|
ISO
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4-phenylbutyric acid results in decreased expression of EFTUD2 mRNA
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CTD |
PMID:14583596 |
|
NCBI chr10:88,304,992...88,352,229
Ensembl chr10:88,304,992...88,346,299
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G
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Egfl7
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EGF-like-domain, multiple 7
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increases expression multiple interactions
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ISO
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4-phenylbutyric acid results in increased expression of EGFL7 mRNA alternative form [decitabine co-treated with 4-phenylbutyric acid] results in increased expression of EGFL7 mRNA alternative form
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CTD |
PMID:19116145 |
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NCBI chr 3:29,802,481...29,814,966
Ensembl chr 3:29,802,690...29,814,951
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G
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Ehd3
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EH-domain containing 3
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increases expression
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ISO
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4-phenylbutyric acid results in increased expression of EHD3 mRNA
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CTD |
PMID:14583596 |
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NCBI chr 6:27,392,709...27,417,445
Ensembl chr 6:27,392,709...27,417,445
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G
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Eif2a
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eukaryotic translation initiation factor 2A
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multiple interactions
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ISO EXP
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4-phenylbutyric acid inhibits the reaction [Cadmium Chloride results in increased phosphorylation of EIF2A protein]; 4-phenylbutyric acid inhibits the reaction [cyanoginosin LR results in increased phosphorylation of EIF2A protein] 4-phenylbutyric acid inhibits the reaction [Ficusin results in increased expression of EIF2A mRNA] 4-phenylbutyric acid inhibits the reaction [[INS co-treated with Acrylamide] results in increased phosphorylation of EIF2A protein]
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CTD |
PMID:31364909 PMID:34175825 PMID:38242296 PMID:38604440 |
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NCBI chr 2:144,911,247...144,944,705
Ensembl chr 2:144,911,153...144,945,201
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G
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Eif2ak3
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eukaryotic translation initiation factor 2 alpha kinase 3
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decreases expression multiple interactions
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EXP ISO
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4-phenylbutyric acid results in decreased expression of EIF2AK3 protein modified form 4-phenylbutyric acid inhibits the reaction [6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide results in increased phosphorylation of EIF2AK3 protein]; 4-phenylbutyric acid inhibits the reaction [[INS co-treated with Acrylamide] results in increased phosphorylation of EIF2AK3 protein]; 4-phenylbutyric acid inhibits the reaction [alpha-Chlorohydrin results in increased expression of and results in increased phosphorylation of EIF2AK3 protein]; 4-phenylbutyric acid inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of EIF2AK3 protein]; 4-phenylbutyric acid inhibits the reaction [Pyrazinamide results in increased phosphorylation of EIF2AK3 protein]; 4-phenylbutyric acid inhibits the reaction [SIRT1 protein affects the phosphorylation of EIF2AK3 protein]; 4-phenylbutyric acid inhibits the reaction [tetrachlorobenzoquinone results in increased expression of EIF2AK3 protein modified form] 4-phenylbutyric acid inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased phosphorylation of EIF2AK3 protein]; 4-phenylbutyric acid inhibits the reaction [Cadmium Chloride results in increased expression of EIF2AK3 protein]; 4-phenylbutyric acid inhibits the reaction [Cisplatin results in increased phosphorylation of EIF2AK3 protein]; 4-phenylbutyric acid inhibits the reaction [Ficusin results in increased phosphorylation of EIF2AK3 protein]; 4-phenylbutyric acid inhibits the reaction [hydroquinone results in increased expression of EIF2AK3 protein]; 4-phenylbutyric acid inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of EIF2AK3 protein]; 4-phenylbutyric acid inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of EIF2AK3 protein modified form]; 4-phenylbutyric acid inhibits the reaction [Potassium Dichromate results in increased expression of EIF2AK3 protein modified form]; 4-phenylbutyric acid inhibits the reaction [Pyrazinamide results in increased phosphorylation of EIF2AK3 protein]; 4-phenylbutyric acid inhibits the reaction [Rifampin results in increased expression of EIF2AK3 mRNA]; 4-phenylbutyric acid inhibits the reaction [Rifampin results in increased expression of EIF2AK3 protein]; 4-phenylbutyric acid inhibits the reaction [SC-66 compound results in increased phosphorylation of EIF2AK3 protein]; mono-(2-ethylhexyl)phthalate inhibits the reaction [4-phenylbutyric acid results in decreased expression of EIF2AK3 protein modified form] 4-phenylbutyric acid results in decreased expression of EIF2AK3 protein; 4-phenylbutyric acid results in decreased expression of EIF2AK3 protein modified form 4-phenylbutyric acid inhibits the reaction [Arecoline results in increased phosphorylation of EIF2AK3 protein]; 4-phenylbutyric acid inhibits the reaction [Busulfan results in increased phosphorylation of EIF2AK3 protein]; 4-phenylbutyric acid inhibits the reaction [cyanoginosin LR results in increased phosphorylation of EIF2AK3 protein]; 4-phenylbutyric acid inhibits the reaction [dibromoacetonitrile results in increased phosphorylation of EIF2AK3 protein]; 4-phenylbutyric acid inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased phosphorylation of EIF2AK3 protein]
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CTD |
PMID:27470132 PMID:27484784 PMID:27638906 PMID:28063906 PMID:28245985 PMID:29653943 PMID:30796460 PMID:31364909 PMID:32569804 PMID:33651226 PMID:34175825 PMID:34533242 PMID:35533795 PMID:36005737 PMID:36646296 PMID:37654027 PMID:37692514 PMID:37741534 PMID:38065397 PMID:38450909 PMID:38604440 More...
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NCBI chr 4:104,363,838...104,425,271
Ensembl chr 4:104,363,833...104,425,268
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G
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Eif2s1
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eukaryotic translation initiation factor 2 subunit alpha
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multiple interactions decreases expression
|
ISO EXP
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4-phenylbutyric acid inhibits the reaction [alpha-Chlorohydrin results in increased expression of and results in increased phosphorylation of EIF2S1 protein]; 4-phenylbutyric acid inhibits the reaction [Amiodarone results in increased phosphorylation of EIF2S1 protein]; 4-phenylbutyric acid inhibits the reaction [Atorvastatin results in increased phosphorylation of EIF2S1 protein]; 4-phenylbutyric acid inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased phosphorylation of EIF2S1 protein]; 4-phenylbutyric acid inhibits the reaction [bisphenol A results in increased phosphorylation of EIF2S1 protein]; 4-phenylbutyric acid inhibits the reaction [Cisplatin results in increased phosphorylation of EIF2S1 protein]; 4-phenylbutyric acid inhibits the reaction [Pyrazinamide results in increased phosphorylation of EIF2S1 protein]; 4-phenylbutyric acid inhibits the reaction [SFTPC protein mutant form results in increased phosphorylation of EIF2S1 protein]; 4-phenylbutyric acid inhibits the reaction [Sodium Selenite results in increased phosphorylation of EIF2S1 protein]; 4-phenylbutyric acid results in decreased expression of and results in increased phosphorylation of EIF2S1 protein 4-phenylbutyric acid results in decreased expression of EIF2S1 protein modified form 4-phenylbutyric acid affects the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in decreased phosphorylation of EIF2S1 protein]; 4-phenylbutyric acid inhibits the reaction [6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide results in increased phosphorylation of EIF2S1 protein]; 4-phenylbutyric acid inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of EIF2S1 mRNA]; 4-phenylbutyric acid inhibits the reaction [Methamphetamine results in increased phosphorylation of EIF2S1 protein]; 4-phenylbutyric acid inhibits the reaction [Pyrazinamide results in increased phosphorylation of EIF2S1 protein]; 4-phenylbutyric acid inhibits the reaction [SIRT1 protein affects the phosphorylation of EIF2S1 protein]; 4-phenylbutyric acid inhibits the reaction [tetrachlorobenzoquinone results in increased expression of EIF2S1 protein modified form] 4-phenylbutyric acid inhibits the reaction [3-acetyldeoxynivalenol results in increased expression of EIF2S1 mRNA]; 4-phenylbutyric acid inhibits the reaction [anandamide results in increased phosphorylation of EIF2S1 protein]; 4-phenylbutyric acid inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of EIF2S1 protein]; 4-phenylbutyric acid inhibits the reaction [Busulfan results in increased phosphorylation of EIF2S1 protein]; 4-phenylbutyric acid inhibits the reaction [Dibutyl Phthalate results in increased expression of EIF2S1 protein modified form]; 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased phosphorylation of EIF2S1 protein]
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CTD |
PMID:20876807 PMID:25295624 PMID:26513129 PMID:26804720 PMID:27484784 PMID:27638049 PMID:27638906 PMID:28063906 PMID:28844859 PMID:29653943 PMID:30602124 PMID:33651226 PMID:34214594 PMID:34520753 PMID:34533242 PMID:35413383 PMID:35533795 PMID:36670177 More...
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NCBI chr 6:103,405,880...103,430,549
Ensembl chr 6:103,405,788...103,431,649
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G
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Ern1
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endoplasmic reticulum to nucleus signaling 1
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multiple interactions decreases expression increases expression
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EXP ISO
|
4-phenylbutyric acid inhibits the reaction [[INS co-treated with Acrylamide] results in increased phosphorylation of ERN1 protein]; 4-phenylbutyric acid inhibits the reaction [alpha-Chlorohydrin results in increased expression of and results in increased phosphorylation of ERN1 protein]; 4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of ERN1 protein modified form] 4-phenylbutyric acid inhibits the reaction [alpha-Chlorohydrin results in increased expression of and results in increased phosphorylation of ERN1 protein]; 4-phenylbutyric acid inhibits the reaction [Asbestos, Amosite results in increased expression of ERN1 protein]; 4-phenylbutyric acid inhibits the reaction [Cadmium Chloride results in increased expression of ERN1 protein]; 4-phenylbutyric acid inhibits the reaction [Hydrogen Peroxide results in increased expression of ERN1 protein]; 4-phenylbutyric acid inhibits the reaction [hydroquinone results in increased expression of ERN1 protein]; 4-phenylbutyric acid inhibits the reaction [Thapsigargin results in increased expression of ERN1 protein] 4-phenylbutyric acid results in decreased expression of ERN1 protein 4-phenylbutyric acid results in increased expression of ERN1 protein 4-phenylbutyric acid inhibits the reaction [3-acetyldeoxynivalenol results in increased expression of ERN1 mRNA]; 4-phenylbutyric acid inhibits the reaction [Arecoline results in increased phosphorylation of ERN1 protein]; 4-phenylbutyric acid inhibits the reaction [Cadmium Chloride results in increased phosphorylation of ERN1 protein]; 4-phenylbutyric acid inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased phosphorylation of ERN1 protein]; 4-phenylbutyric acid promotes the reaction [Palmitic Acid results in increased expression of ERN1 mRNA]
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CTD |
PMID:20399799 PMID:23885834 PMID:29444456 PMID:30796460 PMID:33651226 PMID:34520753 PMID:35413383 PMID:36030031 PMID:36646296 PMID:37692514 PMID:38242296 PMID:38450909 PMID:38604440 More...
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NCBI chr10:91,826,663...91,920,976
Ensembl chr10:91,830,428...91,920,791
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G
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Faah
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fatty acid amide hydrolase
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increases expression
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ISO
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4-phenylbutyric acid results in increased expression of FAAH mRNA
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CTD |
PMID:14583596 |
|
NCBI chr 5:134,716,545...134,735,396
Ensembl chr 5:134,716,545...134,735,396
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G
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Farsb
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phenylalanyl-tRNA synthetase subunit beta
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decreases expression
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ISO
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4-phenylbutyric acid results in decreased expression of FARSB mRNA
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CTD |
PMID:14583596 |
|
NCBI chr 9:87,336,321...87,395,546
Ensembl chr 9:87,336,326...87,395,505
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G
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Fasn
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fatty acid synthase
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multiple interactions
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ISO
|
4-phenylbutyric acid inhibits the reaction [Tunicamycin results in increased expression of FASN mRNA] 4-phenylbutyric acid inhibits the reaction [bisphenol A results in increased expression of FASN mRNA]
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CTD |
PMID:32407927 PMID:36670177 |
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NCBI chr10:106,570,415...106,588,581
Ensembl chr10:106,570,413...106,588,583
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G
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Fbln1
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fibulin 1
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increases expression
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ISO
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4-phenylbutyric acid results in increased expression of FBLN1 mRNA
|
CTD |
PMID:14583596 |
|
NCBI chr 7:118,190,347...118,269,965
Ensembl chr 7:118,190,478...118,269,965
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G
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Fbxo32
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F-box protein 32
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multiple interactions
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EXP
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4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of FBXO32 protein]
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CTD |
PMID:30980806 |
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NCBI chr 7:91,620,925...91,654,491
Ensembl chr 7:91,620,925...91,654,491
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G
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Fgf2
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fibroblast growth factor 2
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decreases expression
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ISO
|
4-phenylbutyric acid results in decreased expression of FGF2 mRNA
|
CTD |
PMID:14583596 |
|
NCBI chr 2:122,164,454...122,218,796
Ensembl chr 2:122,164,454...122,224,493
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G
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Fis1
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fission, mitochondrial 1
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multiple interactions
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ISO EXP
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4-phenylbutyric acid inhibits the reaction [alpha-Chlorohydrin results in increased expression of FIS1 protein]
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CTD |
PMID:33651226 |
|
NCBI chr12:25,345,239...25,360,135
Ensembl chr12:25,345,239...25,349,335
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G
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Fkbp11
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FKBP prolyl isomerase 11
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multiple interactions
|
ISO
|
4-phenylbutyric acid promotes the reaction [LEPR gene mutant form results in increased expression of FKBP11 mRNA]
|
CTD |
PMID:23274897 |
|
NCBI chr 7:131,750,828...131,757,784
Ensembl chr 7:131,750,672...131,770,123
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G
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Fn1
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fibronectin 1
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multiple interactions
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EXP
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4-phenylbutyric acid inhibits the reaction [AGT protein results in increased expression of FN1 protein]
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CTD |
PMID:25398788 |
|
NCBI chr 9:80,645,507...80,714,200
Ensembl chr 9:80,645,507...80,714,137
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G
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Foxo1
|
forkhead box O1
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multiple interactions
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ISO
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4-phenylbutyric acid inhibits the reaction [Palmitic Acid results in decreased expression of FOXO1 mRNA]; 4-phenylbutyric acid inhibits the reaction [Palmitic Acid results in decreased expression of FOXO1 protein]
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CTD |
PMID:36030031 |
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NCBI chr 2:138,462,974...138,541,420
Ensembl chr 2:138,462,697...138,541,419
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G
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Foxo3
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forkhead box O3
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multiple interactions
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ISO EXP
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4-phenylbutyric acid inhibits the reaction [Cadmium Chloride results in increased expression of FOXO3 protein] 4-phenylbutyric acid inhibits the reaction [Methamphetamine results in decreased phosphorylation of FOXO3 protein]
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CTD |
PMID:33127495 PMID:34214594 |
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NCBI chr20:47,251,968...47,348,254
Ensembl chr20:47,255,878...47,346,845
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G
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Gas5
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growth arrest specific 5
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decreases expression
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ISO
|
4-phenylbutyric acid results in decreased expression of GAS5 mRNA
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CTD |
PMID:14583596 |
|
NCBI chr13:75,836,963...75,840,284
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G
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Gas6
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growth arrest specific 6
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decreases expression
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ISO
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4-phenylbutyric acid results in decreased expression of GAS6 mRNA
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CTD |
PMID:14583596 |
|
NCBI chr16:82,747,676...82,778,090
Ensembl chr16:82,747,345...82,778,088
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G
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Gja1
|
gap junction protein, alpha 1
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multiple interactions
|
ISO
|
4-phenylbutyric acid inhibits the reaction [Busulfan results in decreased expression of GJA1 protein]
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CTD |
PMID:35533795 |
|
NCBI chr20:36,302,490...36,315,010
Ensembl chr20:36,302,352...36,319,689
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G
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Gpd2
|
glycerol-3-phosphate dehydrogenase 2
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multiple interactions
|
ISO
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4-phenylbutyric acid inhibits the reaction [LEPR gene mutant form results in decreased expression of GPD2 mRNA]
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CTD |
PMID:23274897 |
|
NCBI chr 3:62,209,432...62,346,590
Ensembl chr 3:62,210,814...62,346,593
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G
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Gpt
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glutamic--pyruvic transaminase
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multiple interactions
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ISO EXP
|
4-phenylbutyric acid inhibits the reaction [Rifampin results in increased expression of GPT protein] 4-phenylbutyric acid inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased activity of GPT protein]; 4-phenylbutyric acid inhibits the reaction [Pyrazinamide results in increased expression of GPT protein] 4-phenylbutyric acid inhibits the reaction [Ficusin results in increased expression of GPT protein]; 4-phenylbutyric acid inhibits the reaction [TAK-875 results in increased expression of GPT protein]; 4-phenylbutyric acid inhibits the reaction [triptolide results in increased expression of GPT protein]
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CTD |
PMID:27470132 PMID:28063906 PMID:28844859 PMID:30243991 PMID:36520315 PMID:39299507 More...
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NCBI chr 7:110,295,599...110,300,134
Ensembl chr 7:110,296,206...110,300,160
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G
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Gpx3
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glutathione peroxidase 3
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increases expression
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ISO
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4-phenylbutyric acid results in increased expression of GPX3 mRNA
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CTD |
PMID:14583596 |
|
NCBI chr10:39,529,335...39,537,406
Ensembl chr10:39,529,448...39,537,405
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G
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Gpx4
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glutathione peroxidase 4
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multiple interactions
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ISO
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4-phenylbutyric acid inhibits the reaction [Particulate Matter results in decreased expression of GPX4 protein]
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CTD |
PMID:36700298 |
|
NCBI chr 7:10,300,833...10,303,629
Ensembl chr 7:10,300,832...10,303,629
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G
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Grb10
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growth factor receptor bound protein 10
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increases expression
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ISO
|
4-phenylbutyric acid results in increased expression of GRB10 mRNA
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CTD |
PMID:14583596 |
|
NCBI chr14:90,708,653...90,816,399
Ensembl chr14:90,708,653...90,816,387
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G
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Gsdmd
|
gasdermin D
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multiple interactions
|
ISO
|
4-phenylbutyric acid inhibits the reaction [Cadmium Chloride results in increased expression of GSDMD mRNA] 4-phenylbutyric acid inhibits the reaction [7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased cleavage of GSDMD protein]; 4-phenylbutyric acid inhibits the reaction [hydroquinone results in increased expression of GSDMD protein]
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CTD |
PMID:30796460 PMID:35297523 PMID:36646296 |
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NCBI chr 7:109,423,209...109,427,771
Ensembl chr 7:109,422,910...109,430,722
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G
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Gsta4
|
glutathione S-transferase alpha 4
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increases expression
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ISO
|
4-phenylbutyric acid results in increased expression of GSTA4 mRNA
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CTD |
PMID:14583596 |
|
NCBI chr 8:87,947,247...87,964,490
Ensembl chr 8:87,930,566...87,964,488
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G
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Hdac1
|
histone deacetylase 1
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multiple interactions
|
ISO
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[4-phenylbutyric acid affects the acetylation of HDAC1 protein] which affects the expression of TUBB3 protein
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CTD |
PMID:18497984 |
|
NCBI chr 5:147,138,328...147,165,387
Ensembl chr 5:147,138,156...147,165,387
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G
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Hdac3
|
histone deacetylase 3
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multiple interactions
|
ISO
|
4-phenylbutyric acid inhibits the reaction [honokiol results in decreased expression of HDAC3 protein]
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CTD |
PMID:34973135 |
|
NCBI chr18:30,021,847...30,041,061
Ensembl chr18:30,021,941...30,041,025
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G
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Hgf
|
hepatocyte growth factor
|
increases expression multiple interactions
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EXP
|
4-phenylbutyric acid results in increased expression of HGF mRNA; 4-phenylbutyric acid results in increased expression of HGF protein 4-phenylbutyric acid inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in decreased expression of HGF mRNA]; 4-phenylbutyric acid inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in decreased expression of HGF protein]; 4-phenylbutyric acid inhibits the reaction [Thapsigargin results in decreased expression of HGF mRNA]; 4-phenylbutyric acid inhibits the reaction [Tunicamycin results in decreased expression of HGF mRNA]; 4-phenylbutyric acid inhibits the reaction [Tunicamycin results in decreased expression of HGF protein]
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CTD |
PMID:28844859 |
|
NCBI chr 4:19,628,902...19,700,467
Ensembl chr 4:19,632,267...19,700,851
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G
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Hk2
|
hexokinase 2
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multiple interactions
|
ISO
|
4-phenylbutyric acid inhibits the reaction [Potassium Dichromate results in increased expression of HK2 protein]
|
CTD |
PMID:32569804 PMID:36473502 |
|
NCBI chr 4:116,792,258...116,841,275
Ensembl chr 4:116,792,258...116,841,275
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G
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Hmga1
|
high mobility group AT-hook 1
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decreases expression
|
ISO
|
4-phenylbutyric acid results in decreased expression of HMGA1 mRNA
|
CTD |
PMID:14583596 |
|
NCBI chr20:5,612,902...5,620,596
Ensembl chr20:5,613,471...5,620,593
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G
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Hmga2
|
high mobility group AT-hook 2
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multiple interactions decreases expression
|
ISO
|
4-phenylbutyric acid inhibits the reaction [Potassium Dichromate results in increased expression of HMGA2 protein]; HMGA2 protein inhibits the reaction [4-phenylbutyric acid results in increased expression of MPC1 protein] 4-phenylbutyric acid results in decreased expression of HMGA2 protein
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CTD |
PMID:36473502 PMID:38992767 |
|
NCBI chr 7:57,762,710...57,884,555
Ensembl chr 7:57,765,675...57,880,341
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G
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Hmox1
|
heme oxygenase 1
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multiple interactions
|
ISO
|
4-phenylbutyric acid inhibits the reaction [Isoniazid results in increased expression of HMOX1 mRNA]
|
CTD |
PMID:40015660 |
|
NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818
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G
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Hnrnpa2b1
|
heterogeneous nuclear ribonucleoprotein A2/B1
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decreases expression
|
ISO
|
4-phenylbutyric acid results in decreased expression of HNRNPA2B1 mRNA
|
CTD |
PMID:14583596 |
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NCBI chr 4:81,867,354...81,875,886
Ensembl chr 4:81,869,661...81,877,572
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G
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Hnrnpc
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heterogeneous nuclear ribonucleoprotein C
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decreases expression
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ISO
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4-phenylbutyric acid results in decreased expression of HNRNPC mRNA
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CTD |
PMID:14583596 |
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NCBI chr15:27,253,098...27,282,779
Ensembl chr15:27,253,098...27,282,715
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G
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Hs6st1
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heparan sulfate 6-O-sulfotransferase 1
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increases expression
|
ISO
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4-phenylbutyric acid results in increased expression of HS6ST mRNA
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CTD |
PMID:14583596 |
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NCBI chr 9:45,779,402...45,818,583
Ensembl chr 9:45,779,019...45,818,582
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G
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Hspa1a
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heat shock protein family A (Hsp70) member 1A
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increases expression
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ISO
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4-phenylbutyric acid results in increased expression of HSPA1A mRNA
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CTD |
PMID:14583596 |
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NCBI chr20:3,875,411...3,877,866
Ensembl chr20:3,855,780...3,877,979
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G
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Hspa2
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heat shock protein family A (Hsp70) member 2
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increases expression
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ISO
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4-phenylbutyric acid results in increased expression of HSPA2 mRNA
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CTD |
PMID:14583596 |
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NCBI chr 6:100,864,172...100,866,946
Ensembl chr 6:100,864,553...100,867,133
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G
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Hspa4l
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heat shock protein family A (Hsp70) member 4 like
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increases expression
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ISO
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4-phenylbutyric acid results in increased expression of HSPA4L mRNA
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CTD |
PMID:14583596 |
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NCBI chr 2:125,668,346...125,726,404
Ensembl chr 2:125,668,236...125,720,986
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G
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Hspa5
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heat shock protein family A (Hsp70) member 5
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multiple interactions decreases expression
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ISO EXP
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2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [4-phenylbutyric acid inhibits the reaction [4-methyl-2,4-bis(4-hydroxyphenyl)pent-1-ene results in increased expression of HSPA5 protein]]; 4-phenylbutyric acid inhibits the reaction [3-acetyldeoxynivalenol results in increased expression of HSPA5 mRNA]; 4-phenylbutyric acid inhibits the reaction [4-methyl-2,4-bis(4-hydroxyphenyl)pent-1-ene results in increased expression of HSPA5 protein]; 4-phenylbutyric acid inhibits the reaction [[2,3,5-trichloro-6-phenyl-(1,4)benzoquinone co-treated with malondialdehyde-low density lipoprotein, human] results in increased expression of HSPA5 mRNA]; 4-phenylbutyric acid inhibits the reaction [Arecoline results in increased expression of HSPA5 protein]; 4-phenylbutyric acid inhibits the reaction [Arsenic Trioxide results in increased expression of HSPA5 protein]; 4-phenylbutyric acid inhibits the reaction [Bilirubin results in increased expression of HSPA5 mRNA]; 4-phenylbutyric acid inhibits the reaction [Busulfan results in increased expression of HSPA5 protein]; 4-phenylbutyric acid inhibits the reaction [Cadmium Chloride results in increased expression of HSPA5 mRNA]; 4-phenylbutyric acid inhibits the reaction [Cadmium Chloride results in increased expression of HSPA5 protein]; 4-phenylbutyric acid inhibits the reaction [dibromoacetonitrile results in increased expression of HSPA5 protein]; 4-phenylbutyric acid inhibits the reaction [Dibutyl Phthalate results in increased expression of HSPA5 protein]; 4-phenylbutyric acid inhibits the reaction [Ficusin results in increased expression of HSPA5 protein]; 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of HSPA5 mRNA]; 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of HSPA5 protein]; 4-phenylbutyric acid inhibits the reaction [Lipopolysaccharides results in increased expression of HSPA5 protein]; 4-phenylbutyric acid inhibits the reaction [Mercuric Chloride results in increased expression of HSPA5 protein]; 4-phenylbutyric acid inhibits the reaction [Palmitic Acid results in increased expression of HSPA5 mRNA]; 4-phenylbutyric acid inhibits the reaction [Palmitic Acid results in increased expression of HSPA5 protein]; 4-phenylbutyric acid inhibits the reaction [Rotenone results in increased expression of HSPA5 protein]; 4-phenylbutyric acid inhibits the reaction [titanium dioxide results in increased expression of HSPA5 mRNA]; 4-phenylbutyric acid inhibits the reaction [titanium dioxide results in increased expression of HSPA5 protein]; 4-phenylbutyric acid inhibits the reaction [Tunicamycin results in increased expression of HSPA5 mRNA]; 4-phenylbutyric acid inhibits the reaction [Tunicamycin results in increased expression of HSPA5 protein] 4-phenylbutyric acid inhibits the reaction [7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased cleavage of HSPA5 protein]; 4-phenylbutyric acid inhibits the reaction [Amiodarone results in increased expression of HSPA5 mRNA]; 4-phenylbutyric acid inhibits the reaction [Cantharidin results in increased expression of HSPA5 protein]; 4-phenylbutyric acid inhibits the reaction [chromium hexavalent ion results in increased expression of HSPA5 protein]; 4-phenylbutyric acid inhibits the reaction [Curcumin results in decreased expression of HSPA5 protein]; 4-phenylbutyric acid inhibits the reaction [discretamine results in increased expression of HSPA5 protein]; 4-phenylbutyric acid inhibits the reaction [Ficusin results in increased expression of HSPA5 mRNA]; 4-phenylbutyric acid inhibits the reaction [Ficusin results in increased expression of HSPA5 protein]; 4-phenylbutyric acid inhibits the reaction [fumonisin B1 results in increased expression of HSPA5 protein]; 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of HSPA5 mRNA]; 4-phenylbutyric acid inhibits the reaction [hydroquinone results in increased expression of HSPA5 protein]; 4-phenylbutyric acid inhibits the reaction [Lipopolysaccharides results in increased expression of HSPA5 protein]; 4-phenylbutyric acid inhibits the reaction [Potassium Dichromate results in increased expression of HSPA5 protein]; 4-phenylbutyric acid inhibits the reaction [Pyrazinamide results in increased expression of HSPA5 protein]; 4-phenylbutyric acid inhibits the reaction [Rifampin results in increased expression of HSPA5 mRNA]; 4-phenylbutyric acid inhibits the reaction [Rifampin results in increased expression of HSPA5 protein]; 4-phenylbutyric acid inhibits the reaction [SC-66 compound results in increased expression of HSPA5 protein]; 4-phenylbutyric acid inhibits the reaction [thymoquinone results in increased expression of HSPA5 protein]; 4-phenylbutyric acid inhibits the reaction [tributyltin results in increased expression of HSPA5 protein]; 4-phenylbutyric acid inhibits the reaction [tris(1,3-dichloro-2-propyl)phosphate results in increased expression of HSPA5 protein]; 4-phenylbutyric acid promotes the reaction [Acetylcysteine inhibits the reaction [tris(1,3-dichloro-2-propyl)phosphate results in increased expression of HSPA5 protein]]; Acetylcysteine promotes the reaction [4-phenylbutyric acid inhibits the reaction [tris(1,3-dichloro-2-propyl)phosphate results in increased expression of HSPA5 protein]]; mono-(2-ethylhexyl)phthalate inhibits the reaction [4-phenylbutyric acid results in decreased expression of HSPA5 protein] 4-phenylbutyric acid inhibits the reaction [4-methyl-2,4-bis(4-hydroxyphenyl)pent-1-ene results in increased expression of HSPA5 protein]; 4-phenylbutyric acid inhibits the reaction [[Air Pollutants results in increased abundance of Particulate Matter] which results in increased expression of HSPA5 protein]; 4-phenylbutyric acid inhibits the reaction [[INS co-treated with Acrylamide] results in increased expression of HSPA5 protein]; 4-phenylbutyric acid inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of HSPA5 mRNA]; 4-phenylbutyric acid inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of HSPA5 protein]; 4-phenylbutyric acid inhibits the reaction [Acrylamide promotes the reaction [elaidic acid results in increased expression of HSPA5 protein]]; 4-phenylbutyric acid inhibits the reaction [Chlormequat results in increased expression of HSPA5 protein]; 4-phenylbutyric acid inhibits the reaction [Dibutyl Phthalate results in increased expression of HSPA5 protein]; 4-phenylbutyric acid inhibits the reaction [elaidic acid promotes the reaction [Acrylamide results in increased expression of HSPA5 protein]]; 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of HSPA5 mRNA]; 4-phenylbutyric acid inhibits the reaction [Lipopolysaccharides results in increased expression of HSPA5 protein]; 4-phenylbutyric acid inhibits the reaction [Pyrazinamide results in increased expression of HSPA5 protein]; 4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of HSPA5 protein]; 4-phenylbutyric acid inhibits the reaction [tetrachlorobenzoquinone results in increased expression of HSPA5 protein]; 4-phenylbutyric acid inhibits the reaction [Thapsigargin results in increased expression of HSPA5 mRNA]; 4-phenylbutyric acid inhibits the reaction [Thapsigargin results in increased expression of HSPA5 protein]; 4-phenylbutyric acid inhibits the reaction [Tunicamycin results in increased expression of HSPA5 mRNA]
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CTD |
PMID:17459145 PMID:20165829 PMID:23743301 PMID:25295624 PMID:26804720 PMID:27470132 PMID:27484784 PMID:27578021 PMID:27638049 PMID:27816613 PMID:28063906 PMID:28245985 PMID:28698385 PMID:28844859 PMID:29981725 PMID:30602124 PMID:30980806 PMID:31298478 PMID:31364909 PMID:31891755 PMID:32407927 PMID:32434321 PMID:32569804 PMID:32590070 PMID:32879258 PMID:33677747 PMID:33771661 PMID:33922211 PMID:34958886 PMID:35297523 PMID:35398186 PMID:35413383 PMID:35533795 PMID:36005737 PMID:36030031 PMID:36640941 PMID:36646296 PMID:37148176 PMID:37654027 PMID:37741534 PMID:38065397 PMID:38242296 PMID:38450909 PMID:38604440 PMID:38740238 PMID:38992767 PMID:39299507 PMID:39442789 More...
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NCBI chr 3:38,453,016...38,457,475
Ensembl chr 3:38,453,041...38,458,790
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G
|
Hspa9
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heat shock protein family A (Hsp70) member 9
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multiple interactions
|
EXP
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4-phenylbutyric acid inhibits the reaction [[Air Pollutants results in increased abundance of Particulate Matter] which results in decreased expression of HSPA9 protein]
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CTD |
PMID:39442789 |
|
NCBI chr18:26,810,004...26,832,958
Ensembl chr18:26,804,774...26,828,398
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G
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Hsph1
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heat shock protein family H (Hsp110) member 1
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increases expression
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ISO
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4-phenylbutyric acid results in increased expression of HSPH1 mRNA
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CTD |
PMID:14583596 |
|
NCBI chr12:10,427,368...10,446,602
Ensembl chr12:10,427,297...10,446,891
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G
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Id1
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inhibitor of DNA binding 1
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decreases expression
|
ISO
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4-phenylbutyric acid results in decreased expression of ID1 mRNA
|
CTD |
PMID:14583596 |
|
NCBI chr 3:161,671,525...161,672,691
Ensembl chr 3:161,671,538...161,672,685
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G
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Ifnb1
|
interferon beta 1
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multiple interactions
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ISO
|
4-phenylbutyric acid inhibits the reaction [3-acetyldeoxynivalenol results in increased expression of and results in increased secretion of IFNB1 protein]; 4-phenylbutyric acid inhibits the reaction [3-acetyldeoxynivalenol results in increased expression of IFNB1 mRNA]
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CTD |
PMID:35413383 |
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NCBI chr 5:108,066,650...108,067,487
Ensembl chr 5:108,066,650...108,067,487
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G
|
Ifng
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interferon gamma
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multiple interactions
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ISO
|
4-phenylbutyric acid inhibits the reaction [3-acetyldeoxynivalenol results in increased expression of IFNG mRNA]; 4-phenylbutyric acid results in decreased expression of and results in decreased secretion of IFNG protein
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CTD |
PMID:35413383 |
|
NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216
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G
|
Il10
|
interleukin 10
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multiple interactions
|
ISO
|
4-phenylbutyric acid inhibits the reaction [3-acetyldeoxynivalenol results in increased expression of and results in increased secretion of IL10 protein]; 4-phenylbutyric acid inhibits the reaction [3-acetyldeoxynivalenol results in increased expression of IL10 mRNA]
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CTD |
PMID:35413383 |
|
NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580
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G
|
Il17a
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interleukin 17A
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multiple interactions
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ISO
|
4-phenylbutyric acid inhibits the reaction [3-acetyldeoxynivalenol results in increased expression of and results in increased secretion of IL17A protein]; 4-phenylbutyric acid inhibits the reaction [3-acetyldeoxynivalenol results in increased expression of IL17A mRNA]
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CTD |
PMID:35413383 |
|
NCBI chr 9:30,640,844...30,644,331
Ensembl chr 9:30,640,844...30,644,331
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G
|
Il18
|
interleukin 18
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multiple interactions
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ISO EXP
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4-phenylbutyric acid inhibits the reaction [Cadmium Chloride results in increased expression of IL18 mRNA] 4-phenylbutyric acid inhibits the reaction [7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of and results in increased secretion of IL18 protein]; 4-phenylbutyric acid inhibits the reaction [hydroquinone results in increased secretion of IL18 protein] 4-phenylbutyric acid inhibits the reaction [Lipopolysaccharides results in increased secretion of IL18 protein]
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CTD |
PMID:30796460 PMID:35297523 PMID:36646296 PMID:37654027 |
|
NCBI chr 8:59,802,072...59,829,275
Ensembl chr 8:59,809,592...59,831,286
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G
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Il1a
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interleukin 1 alpha
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multiple interactions
|
ISO
|
4-phenylbutyric acid inhibits the reaction [3-acetyldeoxynivalenol results in increased expression of and results in increased secretion of IL1A protein]; 4-phenylbutyric acid inhibits the reaction [3-acetyldeoxynivalenol results in increased expression of IL1A mRNA]
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CTD |
PMID:35413383 |
|
NCBI chr 3:136,979,804...136,990,236
Ensembl chr 3:136,979,805...136,998,013
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G
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Il1b
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interleukin 1 beta
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multiple interactions
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ISO EXP
|
4-phenylbutyric acid inhibits the reaction [7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of and results in increased secretion of IL1B protein]; 4-phenylbutyric acid inhibits the reaction [hydroquinone results in increased expression of and results in increased secretion of IL1B protein]; 4-phenylbutyric acid inhibits the reaction [IL1B protein results in increased expression of CXCL8 mRNA]; 4-phenylbutyric acid inhibits the reaction [IL1B protein results in increased expression of IL6 mRNA]; 4-phenylbutyric acid inhibits the reaction [IL1B protein results in increased expression of PTGS2 mRNA] 4-phenylbutyric acid inhibits the reaction [3-acetyldeoxynivalenol results in increased expression of and results in increased secretion of IL1B protein]; 4-phenylbutyric acid inhibits the reaction [3-acetyldeoxynivalenol results in increased expression of IL1B mRNA]; 4-phenylbutyric acid inhibits the reaction [Cadmium Chloride results in increased cleavage of IL1B protein]; 4-phenylbutyric acid inhibits the reaction [Cadmium Chloride results in increased expression of IL1B mRNA]; 4-phenylbutyric acid inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B protein]; 4-phenylbutyric acid inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of IL1B protein] 4-phenylbutyric acid inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]
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CTD |
PMID:17709599 PMID:28245985 PMID:30796460 PMID:35297523 PMID:35413383 PMID:36646296 PMID:37654027 PMID:37692514 More...
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NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601
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G
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Il6
|
interleukin 6
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multiple interactions decreases expression
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ISO
|
4-phenylbutyric acid inhibits the reaction [IL1B protein results in increased expression of IL6 mRNA]; 4-phenylbutyric acid inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein] 4-phenylbutyric acid inhibits the reaction [3-acetyldeoxynivalenol results in increased expression of and results in increased secretion of IL6 protein]; 4-phenylbutyric acid inhibits the reaction [3-acetyldeoxynivalenol results in increased expression of IL6 mRNA]; 4-phenylbutyric acid inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]; 4-phenylbutyric acid inhibits the reaction [SR 1078 results in increased expression of IL6 protein] 4-phenylbutyric acid results in decreased expression of IL6 mRNA
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CTD |
PMID:17709599 PMID:28245985 PMID:28698385 PMID:35413383 |
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NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610
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G
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Ins1
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insulin 1
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multiple interactions
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ISO EXP
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4-phenylbutyric acid inhibits the reaction [Palmitic Acid inhibits the reaction [INS1 protein results in increased uptake of 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose]] 4-phenylbutyric acid inhibits the reaction [Glucosamine inhibits the reaction [INS1 results in increased uptake of Deoxyglucose]]
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CTD |
PMID:20165829 PMID:32283200 |
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NCBI chr 1:261,186,119...261,186,686
Ensembl chr 1:261,186,119...261,186,682
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G
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Ins2
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insulin 2
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multiple interactions
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ISO EXP
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4-phenylbutyric acid inhibits the reaction [Glucosamine inhibits the reaction [INS results in increased uptake of Deoxyglucose]]; 4-phenylbutyric acid inhibits the reaction [Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of AKT1 protein]] 4-phenylbutyric acid inhibits the reaction [[INS co-treated with Acrylamide] results in increased expression of HSPA5 protein]; 4-phenylbutyric acid inhibits the reaction [[INS co-treated with Acrylamide] results in increased phosphorylation of EIF2A protein]; 4-phenylbutyric acid inhibits the reaction [[INS co-treated with Acrylamide] results in increased phosphorylation of EIF2AK3 protein]; 4-phenylbutyric acid inhibits the reaction [[INS co-treated with Acrylamide] results in increased phosphorylation of ERN1 protein]
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CTD |
PMID:20165829 PMID:32283200 PMID:38604440 |
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NCBI chr 1:207,272,738...207,421,998
Ensembl chr 1:207,272,742...207,273,805
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G
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Irs1
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insulin receptor substrate 1
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multiple interactions
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ISO
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4-phenylbutyric acid inhibits the reaction [titanium dioxide results in increased phosphorylation of IRS1 protein]
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CTD |
PMID:31298478 |
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NCBI chr 9:91,001,137...91,053,959
Ensembl chr 9:90,993,519...91,054,538
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G
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Kmt5b
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lysine methyltransferase 5B
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decreases expression
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ISO
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4-phenylbutyric acid results in decreased expression of KMT5B mRNA
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CTD |
PMID:14583596 |
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NCBI chr 1:210,429,672...210,479,042
Ensembl chr 1:210,430,127...210,479,035
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G
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Ldha
|
lactate dehydrogenase A
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multiple interactions
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ISO
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4-phenylbutyric acid inhibits the reaction [Potassium Dichromate results in increased expression of LDHA protein]
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CTD |
PMID:32569804 PMID:36473502 |
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NCBI chr 1:106,508,092...106,517,512
Ensembl chr 1:106,502,182...106,517,521
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G
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Lepr
|
leptin receptor
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multiple interactions
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ISO
|
4-phenylbutyric acid affects the reaction [LEPR gene mutant form affects the splicing of XBP1 mRNA]; 4-phenylbutyric acid inhibits the reaction [LEPR gene mutant form results in decreased expression of GPD2 mRNA]; 4-phenylbutyric acid inhibits the reaction [LEPR gene mutant form results in decreased expression of MAFA mRNA]; 4-phenylbutyric acid inhibits the reaction [LEPR gene mutant form results in decreased expression of NKX6-1 mRNA]; 4-phenylbutyric acid inhibits the reaction [LEPR gene mutant form results in decreased expression of PCX mRNA]; 4-phenylbutyric acid inhibits the reaction [LEPR gene mutant form results in decreased expression of PDX1 mRNA]; 4-phenylbutyric acid promotes the reaction [LEPR gene mutant form results in increased expression of EDEM1 mRNA]; 4-phenylbutyric acid promotes the reaction [LEPR gene mutant form results in increased expression of FKBP11 mRNA]
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CTD |
PMID:23274897 |
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NCBI chr 5:121,409,735...121,593,201
Ensembl chr 5:121,474,099...121,591,215
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G
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Mafa
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MAF bZIP transcription factor A
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multiple interactions
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ISO
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4-phenylbutyric acid inhibits the reaction [LEPR gene mutant form results in decreased expression of MAFA mRNA]
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CTD |
PMID:23274897 |
|
NCBI chr 7:109,313,021...109,315,813
Ensembl chr 7:109,313,121...109,315,760
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G
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Magea9
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MAGE family member A9
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multiple interactions
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ISO
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4-phenylbutyric acid affects the reaction [decitabine affects the expression of MAGEA9 mRNA]; 4-phenylbutyric acid affects the reaction [decitabine affects the expression of MAGEA9 protein]
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CTD |
PMID:17290406 |
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NCBI chr X:147,655,721...147,661,093
Ensembl chr X:147,655,721...147,661,093
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G
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Map1lc3b
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microtubule-associated protein 1 light chain 3 beta
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multiple interactions decreases expression
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ISO EXP
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4-phenylbutyric acid inhibits the reaction [dibromoacetonitrile results in increased expression of and results in increased localization of MAP1LC3B protein]; 4-phenylbutyric acid inhibits the reaction [Dibutyl Phthalate results in increased cleavage of MAP1LC3B protein] 4-phenylbutyric acid inhibits the reaction [Dibutyl Phthalate results in increased cleavage of MAP1LC3B protein]; 4-phenylbutyric acid inhibits the reaction [Lipopolysaccharides results in increased lipidation of MAP1LC3B protein] 4-phenylbutyric acid inhibits the reaction [Curcumin results in decreased expression of MAP1LC3B protein]; 4-phenylbutyric acid inhibits the reaction [flavokawain B results in increased expression of MAP1LC3B protein modified form]; 4-phenylbutyric acid inhibits the reaction [hydroquinone results in increased lipidation of MAP1LC3B protein]; 4-phenylbutyric acid inhibits the reaction [ochratoxin A results in increased expression of MAP1LC3B protein]; 4-phenylbutyric acid inhibits the reaction [Particulate Matter results in increased lipidation of MAP1LC3B protein]; 4-phenylbutyric acid inhibits the reaction [SC-66 compound results in increased lipidation of MAP1LC3B protein]; Curcumin inhibits the reaction [4-phenylbutyric acid results in decreased expression of MAP1LC3B protein]
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CTD |
PMID:26804720 PMID:30025493 PMID:36058351 PMID:36640941 PMID:36700298 PMID:37148176 PMID:37654027 PMID:37741534 PMID:38065397 More...
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NCBI chr19:66,571,631...66,582,270
Ensembl chr19:66,574,407...66,584,358 Ensembl chr16:66,574,407...66,584,358
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G
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Map3k5
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mitogen-activated protein kinase kinase kinase 5
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decreases expression multiple interactions
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ISO
|
4-phenylbutyric acid results in decreased expression of MAP3K5 protein 4-phenylbutyric acid inhibits the reaction [Cadmium Chloride results in increased expression of MAP3K5 protein]
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CTD |
PMID:29444456 |
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NCBI chr 1:16,505,387...16,723,899
Ensembl chr 1:16,505,596...16,723,898
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G
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Mapk1
|
mitogen activated protein kinase 1
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multiple interactions decreases phosphorylation
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EXP ISO
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4-phenylbutyric acid inhibits the reaction [Cytotoxins results in increased phosphorylation of MAPK1 protein] 4-phenylbutyric acid results in decreased phosphorylation of MAPK1 protein
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CTD |
PMID:21147958 PMID:34520753 |
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NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825
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G
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Mapk3
|
mitogen activated protein kinase 3
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multiple interactions decreases phosphorylation
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EXP ISO
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4-phenylbutyric acid inhibits the reaction [Cytotoxins results in increased phosphorylation of MAPK3 protein] 4-phenylbutyric acid results in decreased phosphorylation of MAPK3 protein
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CTD |
PMID:21147958 PMID:34520753 |
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NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411
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G
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Mapk8
|
mitogen-activated protein kinase 8
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multiple interactions
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EXP ISO
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4-phenylbutyric acid inhibits the reaction [Cytotoxins results in increased phosphorylation of MAPK8 protein] 4-phenylbutyric acid inhibits the reaction [3-acetyldeoxynivalenol results in increased expression of MAPK8 mRNA]; 4-phenylbutyric acid inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAPK8 protein] 4-phenylbutyric acid inhibits the reaction [Ficusin results in increased phosphorylation of MAPK8 protein]
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CTD |
PMID:21147958 PMID:31364909 PMID:35413383 PMID:38242296 |
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NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,645,198...8,728,427
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G
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Mapk9
|
mitogen-activated protein kinase 9
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multiple interactions
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EXP
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4-phenylbutyric acid inhibits the reaction [Cytotoxins results in increased phosphorylation of MAPK9 protein]
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CTD |
PMID:21147958 |
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NCBI chr10:34,670,750...34,711,972
Ensembl chr10:34,670,756...34,712,228
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G
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Mat2a
|
methionine adenosyltransferase 2A
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decreases expression
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ISO
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4-phenylbutyric acid results in decreased expression of MAT2A mRNA
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CTD |
PMID:14583596 |
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NCBI chr 4:106,048,043...106,053,612
Ensembl chr 4:106,038,254...106,053,645
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G
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Mecp2
|
methyl CpG binding protein 2
|
multiple interactions
|
ISO
|
[4-phenylbutyric acid affects the acetylation of MECP2 protein] which affects the expression of TUBB3 protein
|
CTD |
PMID:18497984 |
|
NCBI chr X:156,932,481...156,995,981
Ensembl chr X:156,941,234...156,943,560
|
|
G
|
Mef2a
|
myocyte enhancer factor 2a
|
multiple interactions
|
ISO EXP
|
4-phenylbutyric acid inhibits the reaction [Glucosamine results in decreased expression of MEF2A mRNA]; 4-phenylbutyric acid inhibits the reaction [Glucosamine results in decreased expression of MEF2A protein]
|
CTD |
PMID:20165829 |
|
NCBI chr 1:130,258,083...130,392,819
Ensembl chr 1:130,260,339...130,392,162
|
|
G
|
Met
|
MET proto-oncogene, receptor tyrosine kinase
|
multiple interactions
|
EXP
|
4-phenylbutyric acid inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in decreased expression of MET mRNA]
|
CTD |
PMID:28844859 |
|
NCBI chr 4:46,756,823...46,864,041
Ensembl chr 4:46,756,506...46,870,821
|
|
G
|
Mfn2
|
mitofusin 2
|
increases expression multiple interactions
|
EXP ISO
|
4-phenylbutyric acid results in increased expression of MFN2 protein 4-phenylbutyric acid inhibits the reaction [alpha-Chlorohydrin results in decreased expression of MFN2 protein] 4-phenylbutyric acid inhibits the reaction [Ficusin results in decreased expression of MFN2 protein] 4-phenylbutyric acid inhibits the reaction [[Air Pollutants results in increased abundance of Particulate Matter] which results in decreased expression of MFN2 protein]
|
CTD |
PMID:33651226 PMID:39299507 PMID:39442789 |
|
NCBI chr 5:163,587,463...163,617,363
Ensembl chr 5:163,587,463...163,618,495
|
|
G
|
Mief1
|
mitochondrial elongation factor 1
|
decreases expression
|
ISO
|
4-phenylbutyric acid results in decreased expression of MIEF1 mRNA
|
CTD |
PMID:14583596 |
|
NCBI chr 7:113,666,918...113,679,550
Ensembl chr 7:113,666,901...113,683,977
|
|
G
|
Mpc1
|
mitochondrial pyruvate carrier 1
|
increases expression multiple interactions
|
ISO
|
4-phenylbutyric acid results in increased expression of MPC1 protein 4-phenylbutyric acid inhibits the reaction [chromium hexavalent ion results in decreased expression of MPC1 protein]; HMGA2 protein inhibits the reaction [4-phenylbutyric acid results in increased expression of MPC1 protein]
|
CTD |
PMID:38992767 |
|
NCBI chr 1:54,985,305...54,996,979
Ensembl chr 1:54,985,301...54,997,064
|
|
G
|
Mpo
|
myeloperoxidase
|
multiple interactions
|
ISO
|
4-phenylbutyric acid inhibits the reaction [3-acetyldeoxynivalenol results in increased secretion of MPO protein]
|
CTD |
PMID:35413383 |
|
NCBI chr10:73,092,124...73,102,057
Ensembl chr10:73,092,400...73,102,056
|
|
G
|
Mrps18c
|
mitochondrial ribosomal protein S18C
|
decreases expression
|
ISO
|
4-phenylbutyric acid results in decreased expression of MRPS18C mRNA
|
CTD |
PMID:14583596 |
|
NCBI chr14:9,116,688...9,122,943
|
|
G
|
Mrps22
|
mitochondrial ribosomal protein S22
|
decreases expression
|
ISO
|
4-phenylbutyric acid results in decreased expression of MRPS22 mRNA
|
CTD |
PMID:14583596 |
|
NCBI chr 8:108,063,468...108,076,638
Ensembl chr 8:108,063,471...108,076,638
|
|
G
|
Mt-nd1
|
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 1
|
multiple interactions
|
ISO
|
4-phenylbutyric acid inhibits the reaction [Potassium Dichromate results in decreased expression of ND1 protein]
|
CTD |
PMID:36473502 |
|
NCBI chr MT:2,740...3,694
Ensembl chr MT:2,729...3,685
|
|
G
|
Mtor
|
mechanistic target of rapamycin kinase
|
multiple interactions decreases phosphorylation
|
ISO
|
4-phenylbutyric acid inhibits the reaction [Curcumin results in decreased phosphorylation of MTOR protein]; 4-phenylbutyric acid inhibits the reaction [hydroquinone results in decreased phosphorylation of MTOR protein]; 4-phenylbutyric acid inhibits the reaction [Lipopolysaccharides results in decreased phosphorylation of MTOR protein] 4-phenylbutyric acid results in decreased phosphorylation of MTOR protein
|
CTD |
PMID:28245985 PMID:36640941 PMID:37148176 |
|
NCBI chr 5:164,167,985...164,277,438
Ensembl chr 5:164,167,928...164,277,435
|
|
G
|
Ncf1
|
neutrophil cytosolic factor 1
|
multiple interactions
|
EXP
|
4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of NCF1 mRNA]; 4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of NCF1 protein]
|
CTD |
PMID:20399799 |
|
NCBI chr12:28,121,816...28,131,080
Ensembl chr12:28,121,366...28,131,079
|
|
G
|
Ncoa4
|
nuclear receptor coactivator 4
|
multiple interactions
|
ISO
|
4-phenylbutyric acid inhibits the reaction [Particulate Matter results in increased expression of NCOA4 protein]
|
CTD |
PMID:36700298 |
|
NCBI chr16:7,395,502...7,415,846
Ensembl chr16:7,401,802...7,415,840
|
|
G
|
Nde1
|
nudE neurodevelopment protein 1
|
decreases expression
|
ISO
|
4-phenylbutyric acid results in decreased expression of NDE1 mRNA
|
CTD |
PMID:14583596 |
|
NCBI chr10:1,347,010...1,391,167
Ensembl chr10:1,347,018...1,383,447
|
|
G
|
Nfe2l2
|
NFE2 like bZIP transcription factor 2
|
multiple interactions
|
EXP ISO
|
4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of NFE2L2 mRNA]; 4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of NFE2L2 protein] ALPI protein inhibits the reaction [4-phenylbutyric acid results in increased phosphorylation of NFE2L2 protein]
|
CTD |
PMID:20399799 PMID:32407927 |
|
NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:81,001,529...81,029,090
|
|
G
|
Nfkbia
|
NFKB inhibitor alpha
|
multiple interactions
|
ISO
|
4-phenylbutyric acid inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of NFKBIA protein]
|
CTD |
PMID:28245985 |
|
NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:78,593,847...78,597,072
|
|
G
|
Nifk
|
nucleolar protein interacting with the FHA domain of MKI67
|
decreases expression
|
ISO
|
4-phenylbutyric acid results in decreased expression of NIFK mRNA
|
CTD |
PMID:14583596 |
|
NCBI chr13:31,946,119...31,955,950
Ensembl chr13:31,946,108...31,959,561
|
|
G
|
Nkx6-1
|
NK6 homeobox 1
|
multiple interactions
|
ISO
|
4-phenylbutyric acid inhibits the reaction [LEPR gene mutant form results in decreased expression of NKX6-1 mRNA]
|
CTD |
PMID:23274897 |
|
NCBI chr14:8,274,238...8,281,171
Ensembl chr14:8,274,238...8,281,163
|
|
G
|
Nln
|
neurolysin
|
decreases expression
|
ISO
|
4-phenylbutyric acid results in decreased expression of NLN mRNA
|
CTD |
PMID:14583596 |
|
NCBI chr 2:36,867,436...36,966,749
Ensembl chr 2:36,853,551...36,966,680
|
|
G
|
Nlrp3
|
NLR family, pyrin domain containing 3
|
multiple interactions
|
ISO EXP
|
4-phenylbutyric acid inhibits the reaction [Cadmium Chloride results in increased expression of NLRP3 mRNA]; 4-phenylbutyric acid inhibits the reaction [Cadmium Chloride results in increased expression of NLRP3 protein]; 4-phenylbutyric acid inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of NLRP3 protein] 4-phenylbutyric acid inhibits the reaction [7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of NLRP3 protein]; 4-phenylbutyric acid inhibits the reaction [hydroquinone results in increased expression of NLRP3 protein] 4-phenylbutyric acid inhibits the reaction [Lipopolysaccharides results in increased expression of NLRP3 protein]
|
CTD |
PMID:30796460 PMID:35297523 PMID:36646296 PMID:37654027 PMID:37692514 |
|
NCBI chr10:44,826,299...44,853,373
Ensembl chr10:44,828,014...44,853,394
|
|
G
|
Nolc1
|
nucleolar and coiled-body phosphoprotein 1
|
decreases expression
|
ISO
|
4-phenylbutyric acid results in decreased expression of NOLC1 mRNA
|
CTD |
PMID:14583596 |
|
NCBI chr 1:254,870,195...254,881,070
Ensembl chr 1:254,870,319...254,881,069
|
|
G
|
Nom1
|
nucleolar protein with MIF4G domain 1
|
decreases expression
|
ISO
|
4-phenylbutyric acid results in decreased expression of NOM1 mRNA
|
CTD |
PMID:14583596 |
|
NCBI chr 4:6,562,931...6,586,093
Ensembl chr 4:6,567,836...6,585,036
|
|
G
|
Nr1d2
|
nuclear receptor subfamily 1, group D, member 2
|
increases expression
|
ISO
|
4-phenylbutyric acid results in increased expression of NR1D2 mRNA
|
CTD |
PMID:14583596 |
|
NCBI chr15:9,955,034...9,981,329
Ensembl chr15:9,954,906...9,981,330
|
|
G
|
Ocln
|
occludin
|
multiple interactions
|
ISO
|
4-phenylbutyric acid inhibits the reaction [Busulfan results in decreased expression of OCLN protein]
|
CTD |
PMID:35533795 |
|
NCBI chr 2:33,391,303...33,442,207
Ensembl chr 2:33,391,303...33,430,411
|
|
G
|
Opa1
|
OPA1, mitochondrial dynamin like GTPase
|
multiple interactions
|
ISO
|
4-phenylbutyric acid inhibits the reaction [Ficusin results in decreased expression of OPA1 protein]
|
CTD |
PMID:39299507 |
|
NCBI chr11:84,612,943...84,690,025
Ensembl chr11:84,615,340...84,689,955
|
|
G
|
Ostn
|
osteocrin
|
multiple interactions
|
ISO
|
4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of OSTN mRNA]
|
CTD |
PMID:30602124 |
|
NCBI chr11:86,947,023...86,983,322
Ensembl chr11:86,947,313...86,973,427
|
|
G
|
Padi2
|
peptidyl arginine deiminase 2
|
decreases expression
|
ISO
|
4-phenylbutyric acid results in decreased expression of PADI2 mRNA
|
CTD |
PMID:28698385 |
|
NCBI chr 5:158,492,087...158,534,662
Ensembl chr 5:158,492,066...158,534,662
|
|
G
|
Park7
|
Parkinsonism associated deglycase
|
multiple interactions increases expression
|
ISO EXP
|
4-phenylbutyric acid inhibits the reaction [Rotenone results in increased expression of PARK7 protein] 4-phenylbutyric acid results in increased expression of PARK7 mRNA; 4-phenylbutyric acid results in increased expression of PARK7 protein [4-phenylbutyric acid results in increased expression of PARK7 protein] which results in decreased susceptibility to Hydrogen Peroxide; [4-phenylbutyric acid results in increased expression of PARK7 protein] which results in decreased susceptibility to Oxidopamine
|
CTD |
PMID:17459145 PMID:21372141 |
|
NCBI chr 5:166,636,551...166,659,825
Ensembl chr 5:166,636,552...166,659,825
|
|
G
|
Parp1
|
poly (ADP-ribose) polymerase 1
|
multiple interactions
|
ISO EXP
|
4-phenylbutyric acid inhibits the reaction [Acrylamide results in increased cleavage of PARP1 protein]; 4-phenylbutyric acid inhibits the reaction [pendulone results in increased cleavage of PARP1 protein]; 4-phenylbutyric acid inhibits the reaction [SC-66 compound results in increased cleavage of PARP1 protein]; 4-phenylbutyric acid inhibits the reaction [thymoquinone results in increased cleavage of PARP1 protein] 4-phenylbutyric acid inhibits the reaction [Bilirubin results in increased expression of PARP1 protein modified form]; 4-phenylbutyric acid inhibits the reaction [Tunicamycin results in increased expression of PARP1 protein modified form] 4-phenylbutyric acid inhibits the reaction [Methamphetamine results in increased cleavage of PARP1 protein]
|
CTD |
PMID:27578021 PMID:27634458 PMID:29981725 PMID:32407927 PMID:34214594 PMID:35288263 PMID:37741534 More...
|
|
NCBI chr13:94,839,484...94,871,295
Ensembl chr13:94,839,433...94,871,567
|
|
G
|
Pawr
|
pro-apoptotic WT1 regulator
|
decreases expression
|
ISO
|
4-phenylbutyric acid results in decreased expression of PAWR mRNA
|
CTD |
PMID:14583596 |
|
NCBI chr 7:45,531,480...45,611,492
Ensembl chr 7:45,531,637...45,611,492
|
|
G
|
Pc
|
pyruvate carboxylase
|
multiple interactions
|
ISO
|
4-phenylbutyric acid inhibits the reaction [LEPR gene mutant form results in decreased expression of PCX mRNA]
|
CTD |
PMID:23274897 |
|
NCBI chr 1:211,228,708...211,327,792
Ensembl chr 1:211,228,731...211,329,940
|
|
G
|
Pdcd2l
|
programmed cell death 2-like
|
decreases expression
|
ISO
|
4-phenylbutyric acid results in decreased expression of PDCD2L mRNA
|
CTD |
PMID:14583596 |
|
NCBI chr 1:95,947,476...95,959,738
Ensembl chr 1:95,947,476...95,959,906
|
|
G
|
Pdx1
|
pancreatic and duodenal homeobox 1
|
multiple interactions
|
ISO
|
4-phenylbutyric acid inhibits the reaction [LEPR gene mutant form results in decreased expression of PDX1 mRNA]
|
CTD |
PMID:23274897 |
|
NCBI chr12:12,793,957...12,799,156
Ensembl chr12:12,793,957...12,799,156
|
|
G
|
Phgdh
|
phosphoglycerate dehydrogenase
|
multiple interactions
|
ISO
|
4-phenylbutyric acid inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of PHGDH protein]
|
CTD |
PMID:39427783 |
|
NCBI chr 2:188,595,700...188,624,789
Ensembl chr 2:188,595,700...188,624,789
|
|
G
|
Pink1
|
PTEN induced kinase 1
|
multiple interactions
|
ISO
|
4-phenylbutyric acid inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of PINK1 protein]
|
CTD |
PMID:37692514 |
|
NCBI chr 5:155,813,838...155,825,950
Ensembl chr 5:155,813,838...155,825,950
|
|
G
|
Pkm
|
pyruvate kinase M1/2
|
multiple interactions
|
ISO
|
4-phenylbutyric acid inhibits the reaction [Potassium Dichromate results in increased expression of PKM protein]
|
CTD |
PMID:32569804 PMID:36473502 |
|
NCBI chr 8:68,949,731...68,975,394
Ensembl chr 8:68,948,815...68,975,396
|
|
G
|
Pole4
|
DNA polymerase epsilon 4, accessory subunit
|
decreases expression
|
ISO
|
4-phenylbutyric acid results in decreased expression of POLE4 mRNA
|
CTD |
PMID:14583596 |
|
NCBI chr 4:116,723,040...116,728,873
Ensembl chr 4:116,716,719...116,728,851
|
|
G
|
Polr1h
|
RNA polymerase I subunit H
|
decreases expression
|
ISO
|
4-phenylbutyric acid results in decreased expression of POLR1H mRNA
|
CTD |
PMID:14583596 |
|
NCBI chr20:1,600,170...1,604,088
Ensembl chr20:1,595,945...1,604,088
|
|
G
|
Polr2a
|
RNA polymerase II subunit A
|
increases expression decreases expression
|
ISO
|
4-phenylbutyric acid results in increased expression of POLR2A mRNA 4-phenylbutyric acid results in decreased expression of POLR2A mRNA
|
CTD |
PMID:14583596 |
|
NCBI chr10:54,951,162...54,977,179
Ensembl chr10:54,951,162...54,977,179
|
|
G
|
Pparg
|
peroxisome proliferator-activated receptor gamma
|
multiple interactions
|
ISO
|
4-phenylbutyric acid inhibits the reaction [bisphenol A results in increased expression of PPARG mRNA]
|
CTD |
PMID:36670177 |
|
NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:150,095,787...150,221,104
|
|
G
|
Ppargc1a
|
PPARG coactivator 1 alpha
|
multiple interactions
|
ISO EXP
|
4-phenylbutyric acid inhibits the reaction [Glucosamine results in decreased expression of PPARGC1A mRNA]; 4-phenylbutyric acid inhibits the reaction [Glucosamine results in decreased expression of PPARGC1A protein] 4-phenylbutyric acid inhibits the reaction [Glucose results in decreased expression of PPARGC1A mRNA]
|
CTD |
PMID:20165829 PMID:28482072 |
|
NCBI chr14:63,073,505...63,729,215
Ensembl chr14:63,273,189...63,729,213
|
|
G
|
Ppil1
|
peptidylprolyl isomerase like 1
|
decreases expression
|
ISO
|
4-phenylbutyric acid results in decreased expression of PPIL1 mRNA
|
CTD |
PMID:14583596 |
|
NCBI chr20:7,303,919...7,323,962
Ensembl chr20:7,303,922...7,318,781
|
|
G
|
Ptgs2
|
prostaglandin-endoperoxide synthase 2
|
multiple interactions
|
ISO
|
4-phenylbutyric acid inhibits the reaction [IL1B protein results in increased expression of PTGS2 mRNA]; 4-phenylbutyric acid inhibits the reaction [Particulate Matter results in increased expression of PTGS2 protein]
|
CTD |
PMID:17709599 PMID:36700298 |
|
NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320
|
|
G
|
Pycard
|
PYD and CARD domain containing
|
multiple interactions
|
ISO
|
4-phenylbutyric acid inhibits the reaction [Cadmium Chloride results in increased expression of PYCARD mRNA] 4-phenylbutyric acid inhibits the reaction [hydroquinone results in increased expression of PYCARD protein]
|
CTD |
PMID:30796460 PMID:36646296 |
|
NCBI chr 1:192,032,124...192,033,419
Ensembl chr 1:192,032,124...192,033,419
|
|
G
|
Rbm8a
|
RNA binding motif protein 8A
|
decreases expression
|
ISO
|
4-phenylbutyric acid results in decreased expression of RBM8A mRNA
|
CTD |
PMID:14583596 |
|
NCBI chr 2:186,854,018...186,856,802
Ensembl chr 2:186,854,036...186,856,802
|
|
G
|
Rela
|
RELA proto-oncogene, NF-kB subunit
|
multiple interactions
|
ISO
|
4-phenylbutyric acid inhibits the reaction [honokiol results in decreased expression of RELA protein]; 4-phenylbutyric acid inhibits the reaction [hydroquinone results in increased phosphorylation of RELA protein]; 4-phenylbutyric acid inhibits the reaction [Lipopolysaccharides affects the localization of RELA protein]
|
CTD |
PMID:28245985 PMID:34973135 PMID:36646296 |
|
NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817
|
|
G
|
Rmdn3
|
regulator of microtubule dynamics 3
|
multiple interactions
|
EXP
|
4-phenylbutyric acid inhibits the reaction [[Air Pollutants results in increased abundance of Particulate Matter] which results in decreased expression of RMDN3 protein]
|
CTD |
PMID:39442789 |
|
NCBI chr 3:126,579,811...126,601,016
Ensembl chr 3:126,579,812...126,600,418
|
|
G
|
Rnf185
|
ring finger protein 185
|
multiple interactions
|
EXP
|
4-phenylbutyric acid inhibits the reaction [Chlormequat results in increased expression of RNF185 protein]
|
CTD |
PMID:34958886 |
|
NCBI chr14:82,516,153...82,554,199
Ensembl chr14:82,516,154...82,553,466
|
|
G
|
Rpl7a
|
ribosomal protein L7A
|
decreases expression
|
ISO
|
4-phenylbutyric acid results in decreased expression of RPL7A mRNA
|
CTD |
PMID:14583596 |
|
NCBI chr 3:30,637,136...30,639,778
Ensembl chr 3:30,637,059...30,639,791 Ensembl chr18:30,637,059...30,639,791
|
|
G
|
RT1-A2
|
RT1 class Ia, locus A2
|
increases expression
|
ISO
|
4-phenylbutyric acid results in increased expression of HLA-E mRNA
|
CTD |
PMID:14583596 |
|
NCBI chr20:4,872,720...4,876,425
|
|
G
|
Sarnp
|
SAP domain containing ribonucleoprotein
|
decreases expression
|
ISO
|
4-phenylbutyric acid results in decreased expression of SARNP mRNA
|
CTD |
PMID:14583596 |
|
NCBI chr 7:1,835,597...1,889,833
Ensembl chr 7:1,835,597...1,897,295
|
|
G
|
Sesn2
|
sestrin 2
|
multiple interactions
|
ISO
|
4-phenylbutyric acid inhibits the reaction [Tunicamycin results in increased expression of SESN2 mRNA]; 4-phenylbutyric acid inhibits the reaction [Tunicamycin results in increased expression of SESN2 protein]
|
CTD |
PMID:32407927 |
|
NCBI chr 5:149,986,304...150,005,255
Ensembl chr 5:149,986,317...150,005,255
|
|
G
|
Sftpc
|
surfactant protein C
|
multiple interactions
|
ISO
|
4-phenylbutyric acid inhibits the reaction [SFTPC protein mutant form results in increased cleavage of CASP3 protein]; 4-phenylbutyric acid inhibits the reaction [SFTPC protein mutant form results in increased cleavage of CTSD protein]; 4-phenylbutyric acid inhibits the reaction [SFTPC protein mutant form results in increased expression of ADAM17 protein]; 4-phenylbutyric acid inhibits the reaction [SFTPC protein mutant form results in increased expression of ATF6 protein]; 4-phenylbutyric acid inhibits the reaction [SFTPC protein mutant form results in increased expression of XBP1 protein alternative form]; 4-phenylbutyric acid inhibits the reaction [SFTPC protein mutant form results in increased phosphorylation of EIF2S1 protein]
|
CTD |
PMID:27638906 |
|
NCBI chr15:52,006,274...52,009,324
Ensembl chr15:52,006,283...52,009,475
|
|
G
|
Sirt1
|
sirtuin 1
|
multiple interactions
|
EXP
|
4-phenylbutyric acid inhibits the reaction [SIRT1 protein affects the expression of ATF4 mRNA]; 4-phenylbutyric acid inhibits the reaction [SIRT1 protein affects the expression of DDIT3 mRNA]; 4-phenylbutyric acid inhibits the reaction [SIRT1 protein affects the expression of DDIT3 protein]; 4-phenylbutyric acid inhibits the reaction [SIRT1 protein affects the phosphorylation of EIF2AK3 protein]; 4-phenylbutyric acid inhibits the reaction [SIRT1 protein affects the phosphorylation of EIF2S1 protein]
|
CTD |
PMID:29653943 |
|
NCBI chr20:25,305,953...25,328,000
Ensembl chr20:25,305,476...25,328,000
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G
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Slc22a18
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solute carrier family 22, member 18
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increases expression
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ISO
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4-phenylbutyric acid results in increased expression of SLC67A1 mRNA
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CTD |
PMID:14583596 |
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NCBI chr 1:208,100,032...208,124,382
Ensembl chr 1:208,101,136...208,124,380
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G
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Slc2a1
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solute carrier family 2 member 1
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multiple interactions
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ISO
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4-phenylbutyric acid inhibits the reaction [Potassium Dichromate results in increased expression of SLC2A1 protein]
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CTD |
PMID:32569804 PMID:36473502 |
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NCBI chr 5:138,002,522...138,030,742
Ensembl chr 5:138,002,522...138,030,742
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G
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Slc2a4
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solute carrier family 2 member 4
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multiple interactions
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EXP ISO
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4-phenylbutyric acid inhibits the reaction [Glucosamine results in decreased expression of SLC2A4 mRNA]; 4-phenylbutyric acid inhibits the reaction [Glucosamine results in decreased expression of SLC2A4 protein]
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CTD |
PMID:20165829 |
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NCBI chr10:55,164,721...55,170,289
Ensembl chr10:55,164,721...55,170,270
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G
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Slc38a2
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solute carrier family 38, member 2
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multiple interactions
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ISO
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4-phenylbutyric acid inhibits the reaction [arsenite results in increased expression of SLC38A2 mRNA]
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CTD |
PMID:22215663 |
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NCBI chr 7:129,730,450...129,742,619
Ensembl chr 7:129,730,450...129,742,619
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G
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Slc44a2
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solute carrier family 44 member 2
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increases expression
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ISO
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4-phenylbutyric acid results in increased expression of CTL2 mRNA
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CTD |
PMID:14583596 |
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NCBI chr 8:28,147,023...28,181,496
Ensembl chr 8:28,147,030...28,181,495
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G
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Slc5a6
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solute carrier family 5 member 6
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multiple interactions increases expression
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ISO
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mono-(2-ethylhexyl)phthalate inhibits the reaction [4-phenylbutyric acid results in increased expression of SLC5A6 protein]
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CTD |
PMID:36005737 |
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NCBI chr 6:31,039,865...31,051,671
Ensembl chr 6:31,040,017...31,051,670
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G
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Slc7a11
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solute carrier family 7 member 11
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multiple interactions
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ISO
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4-phenylbutyric acid inhibits the reaction [Particulate Matter results in decreased expression of SLC7A11 protein]
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CTD |
PMID:36700298 |
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NCBI chr 2:136,532,912...136,668,560
Ensembl chr 2:136,532,246...136,695,695
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G
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Slu7
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SLU7 homolog, splicing factor
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decreases expression
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ISO
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4-phenylbutyric acid results in decreased expression of SLU7 mRNA
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CTD |
PMID:14583596 |
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NCBI chr10:28,406,908...28,425,253
Ensembl chr10:28,409,846...28,425,250
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G
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Snca
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synuclein alpha
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multiple interactions
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ISO
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4-phenylbutyric acid inhibits the reaction [Rotenone results in increased expression of SNCA protein]; 4-phenylbutyric acid inhibits the reaction [SNCA protein binds to SNCA protein]
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CTD |
PMID:17459145 PMID:21372141 |
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NCBI chr 4:91,026,474...91,127,444
Ensembl chr 4:91,026,474...91,126,315
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G
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Snx5
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sorting nexin 5
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decreases expression
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ISO
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4-phenylbutyric acid results in decreased expression of SNX5 mRNA
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CTD |
PMID:14583596 |
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NCBI chr 3:152,075,258...152,094,508
Ensembl chr 3:152,075,258...152,094,877
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G
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Sod1
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superoxide dismutase 1
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multiple interactions
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ISO
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4-phenylbutyric acid inhibits the reaction [perfluorooctanoic acid results in increased expression of SOD1 mRNA]; [4-phenylbutyric acid co-treated with Thapsigargin] results in increased expression of SOD1 mRNA
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CTD |
PMID:32578922 |
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NCBI chr11:42,942,742...42,948,399
Ensembl chr11:42,942,678...42,948,399
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G
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Sod3
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superoxide dismutase 3
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multiple interactions increases expression
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EXP
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4-phenylbutyric acid inhibits the reaction [cobaltous chloride results in decreased expression of SOD3 mRNA] 4-phenylbutyric acid results in increased expression of SOD3 mRNA
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CTD |
PMID:21804221 |
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NCBI chr14:62,822,865...62,828,602
Ensembl chr14:62,811,177...62,829,125
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G
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Sox4
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SRY-box transcription factor 4
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decreases expression
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ISO
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4-phenylbutyric acid results in decreased expression of SOX4 mRNA
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CTD |
PMID:14583596 |
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NCBI chr17:35,876,298...35,881,004
Ensembl chr17:35,875,756...35,884,024
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G
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Sqstm1
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sequestosome 1
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multiple interactions increases expression
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ISO
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4-phenylbutyric acid inhibits the reaction [Cadmium Chloride results in decreased expression of SQSTM1 protein]; 4-phenylbutyric acid inhibits the reaction [Curcumin results in decreased expression of SQSTM1 protein]; 4-phenylbutyric acid inhibits the reaction [Particulate Matter results in decreased expression of SQSTM1 protein]; 4-phenylbutyric acid inhibits the reaction [Potassium Dichromate results in decreased expression of SQSTM1 protein]; 4-phenylbutyric acid inhibits the reaction [SC-66 compound results in decreased expression of SQSTM1 protein] 4-phenylbutyric acid results in increased expression of SQSTM1 protein
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CTD |
PMID:32569804 PMID:33127495 PMID:36640941 PMID:36700298 PMID:37741534 |
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NCBI chr10:35,026,598...35,037,750
Ensembl chr10:35,026,598...35,037,750
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G
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Srebf1
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sterol regulatory element binding transcription factor 1
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multiple interactions
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EXP ISO
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4-phenylbutyric acid inhibits the reaction [AGT protein results in increased cleavage of SREBF1 protein]; 4-phenylbutyric acid inhibits the reaction [AGT protein results in increased expression of SREBF1 mRNA] 4-phenylbutyric acid inhibits the reaction [bisphenol A results in increased expression of SREBF1 mRNA]
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CTD |
PMID:25398788 PMID:36670177 |
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NCBI chr10:45,507,152...45,529,164
Ensembl chr10:45,507,152...45,529,164
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G
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Srsf10
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serine and arginine rich splicing factor 10
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decreases expression
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ISO
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4-phenylbutyric acid results in decreased expression of SRSF10 mRNA
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CTD |
PMID:14583596 |
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NCBI chr 5:153,372,307...153,386,520
Ensembl chr 5:153,372,316...153,386,513
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G
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Syvn1
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synoviolin 1
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decreases expression multiple interactions
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ISO EXP
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4-phenylbutyric acid results in decreased expression of SYVN1 mRNA 4-phenylbutyric acid inhibits the reaction [Streptozocin results in decreased expression of SYVN1 protein]
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CTD |
PMID:14583596 PMID:30980806 |
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NCBI chr 1:212,766,736...212,775,426
Ensembl chr 1:212,768,907...212,776,457
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G
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Tax1bp1
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Tax1 binding protein 1
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decreases expression
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ISO
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4-phenylbutyric acid results in decreased expression of TAX1BP1 mRNA
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CTD |
PMID:14583596 |
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NCBI chr 4:83,152,549...83,208,463
Ensembl chr 4:83,110,062...83,209,657
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G
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Tax1bp3
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Tax1 binding protein 3
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decreases expression
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ISO
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4-phenylbutyric acid results in decreased expression of TAX1BP3 mRNA
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CTD |
PMID:14583596 |
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NCBI chr10:58,294,357...58,298,875
Ensembl chr10:58,294,073...58,298,875
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G
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Tg
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thyroglobulin
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multiple interactions
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ISO
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4-phenylbutyric acid inhibits the reaction [Amiodarone results in decreased expression of TG protein]; 4-phenylbutyric acid inhibits the reaction [mono-(2-ethylhexyl)phthalate results in decreased expression of TG protein]
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CTD |
PMID:25295624 PMID:36005737 |
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NCBI chr 7:100,307,349...100,492,246
Ensembl chr 7:100,307,349...100,314,539 Ensembl chr 7:100,307,349...100,314,539
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G
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Tgfb1
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transforming growth factor, beta 1
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decreases expression
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ISO
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4-phenylbutyric acid results in decreased expression of TGFB1 protein
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CTD |
PMID:25450231 |
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NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899
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G
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Th
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tyrosine hydroxylase
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increases expression
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ISO
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4-phenylbutyric acid results in increased expression of TH protein
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CTD |
PMID:21372141 |
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NCBI chr 1:207,500,959...207,508,276
Ensembl chr 1:207,500,962...207,557,227
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G
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Timm50
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translocase of inner mitochondrial membrane 50
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decreases expression
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ISO
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4-phenylbutyric acid results in decreased expression of TIMM50 mRNA
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CTD |
PMID:14583596 |
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NCBI chr 1:92,702,437...92,710,311
Ensembl chr 1:92,702,437...92,710,311
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G
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Tmed5
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transmembrane p24 trafficking protein 5
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increases expression decreases expression
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ISO
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4-phenylbutyric acid results in increased expression of TMED5 mRNA 4-phenylbutyric acid results in decreased expression of TMED5 mRNA
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CTD |
PMID:14583596 |
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NCBI chr14:1,752,857...1,763,990
Ensembl chr14:1,752,745...1,773,389
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G
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Tmpo
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thymopoietin
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decreases expression
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ISO
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4-phenylbutyric acid results in decreased expression of TMPO mRNA
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CTD |
PMID:14583596 |
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NCBI chr 7:27,529,977...27,554,980
Ensembl chr 7:27,529,978...27,554,937
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G
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Tnf
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tumor necrosis factor
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multiple interactions decreases expression
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ISO
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4-phenylbutyric acid inhibits the reaction [3-acetyldeoxynivalenol results in increased expression of and results in increased secretion of TNF protein]; 4-phenylbutyric acid inhibits the reaction [3-acetyldeoxynivalenol results in increased expression of TNF mRNA]; 4-phenylbutyric acid inhibits the reaction [Bilirubin results in increased expression of TNF mRNA]; 4-phenylbutyric acid inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; 4-phenylbutyric acid inhibits the reaction [SR 1078 results in increased expression of TNF protein] 4-phenylbutyric acid results in decreased expression of TNF mRNA
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CTD |
PMID:27578021 PMID:28245985 PMID:28698385 PMID:35413383 |
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NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
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G
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Tp53
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tumor protein p53
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multiple interactions
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EXP
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4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of TP53 protein]
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CTD |
PMID:30980806 |
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NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299
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G
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Tra2a
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transformer 2 alpha
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decreases expression
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ISO
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4-phenylbutyric acid results in decreased expression of TRA2A mRNA
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CTD |
PMID:14583596 |
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NCBI chr 4:79,551,699...79,570,621
Ensembl chr 4:79,551,542...79,570,619
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G
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Tsc2
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TSC complex subunit 2
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increases expression
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ISO
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4-phenylbutyric acid results in increased expression of TSC2 mRNA
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CTD |
PMID:14583596 |
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NCBI chr10:14,125,679...14,160,317
Ensembl chr10:14,125,680...14,160,600
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G
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Tsr1
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TSR1, ribosome maturation factor
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decreases expression
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ISO
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4-phenylbutyric acid results in decreased expression of TSR1 mRNA
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CTD |
PMID:14583596 |
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NCBI chr10:60,258,790...60,270,238
Ensembl chr10:60,258,784...60,274,309
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G
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Tubb3
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tubulin, beta 3 class III
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multiple interactions affects expression
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ISO
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[4-phenylbutyric acid affects the acetylation of HDAC1 protein] which affects the expression of TUBB3 protein; [4-phenylbutyric acid affects the acetylation of MECP2 protein] which affects the expression of TUBB3 protein; [decitabine co-treated with 4-phenylbutyric acid] affects the expression of TUBB3 protein 4-phenylbutyric acid affects the expression of TUBB3 protein
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CTD |
PMID:18497984 |
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NCBI chr19:68,365,687...68,374,741
Ensembl chr19:68,365,587...68,374,740
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G
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Uba1
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ubiquitin-like modifier activating enzyme 1
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multiple interactions
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EXP
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4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of UBA1 protein]
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CTD |
PMID:30980806 |
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NCBI chr X:4,062,216...4,084,192
Ensembl chr X:4,062,182...4,084,246
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G
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Uba6
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ubiquitin-like modifier activating enzyme 6
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decreases expression
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ISO
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4-phenylbutyric acid results in decreased expression of UBA6 mRNA
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CTD |
PMID:14583596 |
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NCBI chr14:22,238,832...22,302,650
Ensembl chr14:22,211,601...22,302,650
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G
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Ube2d1
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ubiquitin-conjugating enzyme E2D 1
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multiple interactions
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EXP
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4-phenylbutyric acid inhibits the reaction [Chlormequat results in increased expression of UBE2D1 protein]
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CTD |
PMID:34958886 |
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NCBI chr20:17,308,459...17,341,427
Ensembl chr20:17,331,646...17,341,427
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G
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Ube2w
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ubiquitin-conjugating enzyme E2W
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decreases expression
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ISO
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4-phenylbutyric acid results in decreased expression of UBE2W mRNA
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CTD |
PMID:14583596 |
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NCBI chr 5:7,474,039...7,531,526
Ensembl chr 5:7,474,003...7,598,245
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G
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Uchl1
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ubiquitin C-terminal hydrolase L1
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multiple interactions
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EXP
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4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of UCHL1 protein]
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CTD |
PMID:30980806 |
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NCBI chr14:41,838,859...41,849,743
Ensembl chr14:41,838,861...41,849,417
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G
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Uchl5
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ubiquitin C-terminal hydrolase L5
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multiple interactions
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EXP
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4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of UCHL5 protein]
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CTD |
PMID:30980806 |
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NCBI chr13:58,070,947...58,106,825
Ensembl chr13:58,042,029...58,107,441
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G
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Umod
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uromodulin
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increases expression
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ISO
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4-phenylbutyric acid results in increased expression of UMOD protein; 4-phenylbutyric acid results in increased expression of UMOD protein mutant form
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CTD |
PMID:24567330 |
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NCBI chr 1:183,247,676...183,261,665
Ensembl chr 1:183,247,674...183,261,030
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G
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Utp4
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UTP4 small subunit processome component
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decreases expression
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ISO
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4-phenylbutyric acid results in decreased expression of UTP4 mRNA
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CTD |
PMID:14583596 |
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NCBI chr19:51,696,437...51,730,323
Ensembl chr19:51,701,739...51,730,325
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G
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Vapb
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VAMP associated protein B and C
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multiple interactions
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EXP
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4-phenylbutyric acid inhibits the reaction [[Air Pollutants results in increased abundance of Particulate Matter] which results in decreased expression of VAPB protein]
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CTD |
PMID:39442789 |
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NCBI chr 3:182,954,247...182,997,018
Ensembl chr 3:182,954,240...183,028,619
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G
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Vcp
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valosin-containing protein
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multiple interactions
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EXP
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4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of VCP protein]
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CTD |
PMID:30980806 |
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NCBI chr 5:62,005,984...62,025,387
Ensembl chr 5:62,005,985...62,025,387
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G
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Vdac1
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voltage-dependent anion channel 1
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multiple interactions
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EXP
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4-phenylbutyric acid inhibits the reaction [[Air Pollutants results in increased abundance of Particulate Matter] which results in decreased expression of VDAC1 protein]
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CTD |
PMID:39442789 |
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NCBI chr10:37,029,377...37,060,542
Ensembl chr10:37,023,145...37,060,541
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G
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Vegfa
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vascular endothelial growth factor A
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decreases expression multiple interactions
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EXP
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4-phenylbutyric acid results in decreased expression of VEGFA protein 4-phenylbutyric acid inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of VEGFA mRNA]; 4-phenylbutyric acid inhibits the reaction [Thapsigargin results in increased expression of VEGFA mRNA]; 4-phenylbutyric acid inhibits the reaction [Thapsigargin results in increased expression of VEGFA protein]; 4-phenylbutyric acid inhibits the reaction [Tunicamycin results in increased expression of VEGFA mRNA]; 4-phenylbutyric acid inhibits the reaction [Tunicamycin results in increased expression of VEGFA protein]
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CTD |
PMID:28844859 |
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NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:22,439,392...22,468,194
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G
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Wdr4
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WD repeat domain 4
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decreases expression
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ISO
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4-phenylbutyric acid results in decreased expression of WDR4 mRNA
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CTD |
PMID:14583596 |
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NCBI chr20:9,588,532...9,604,718
Ensembl chr20:9,588,532...9,605,007
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G
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Wwtr1
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WW domain containing transcription regulator 1
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decreases expression
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ISO
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4-phenylbutyric acid results in decreased expression of WWTR1 mRNA
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CTD |
PMID:14583596 |
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NCBI chr 2:143,801,181...143,916,941
Ensembl chr 2:143,801,181...143,991,950
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G
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Xbp1
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X-box binding protein 1
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multiple interactions decreases expression
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ISO EXP
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4-phenylbutyric acid inhibits the reaction [[Amiodarone results in increased splicing of XBP1 mRNA] which results in increased expression of XBP1 mRNA alternative form]; 4-phenylbutyric acid inhibits the reaction [Amiodarone results in increased expression of XBP1 mRNA]; 4-phenylbutyric acid inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of XBP1 protein alternative form]; 4-phenylbutyric acid inhibits the reaction [bisphenol A results in increased expression of XBP1 protein alternative form]; 4-phenylbutyric acid inhibits the reaction [Cadmium Chloride results in increased expression of XBP1 protein alternative form]; 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of XBP1 mRNA]; 4-phenylbutyric acid inhibits the reaction [Lipopolysaccharides results in increased expression of XBP1 protein alternative form]; 4-phenylbutyric acid inhibits the reaction [SFTPC protein mutant form results in increased expression of XBP1 protein alternative form] 4-phenylbutyric acid inhibits the reaction [alpha-Chlorohydrin results in increased expression of XBP1 protein alternative form]; 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of XBP1 mRNA]; 4-phenylbutyric acid inhibits the reaction [Methamphetamine results in increased expression of XBP1 protein alternative form] 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [4-phenylbutyric acid inhibits the reaction [4-methyl-2,4-bis(4-hydroxyphenyl)pent-1-ene results in increased expression of XBP1 protein alternative form]]; 4-phenylbutyric acid affects the reaction [LEPR gene mutant form affects the splicing of XBP1 mRNA]; 4-phenylbutyric acid inhibits the reaction [3-acetyldeoxynivalenol results in increased expression of XBP1 mRNA]; 4-phenylbutyric acid inhibits the reaction [4-methyl-2,4-bis(4-hydroxyphenyl)pent-1-ene results in increased expression of XBP1 protein alternative form]; 4-phenylbutyric acid inhibits the reaction [Bilirubin results in increased expression of XBP1 mRNA]; 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of XBP1 protein alternative form]; 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased splicing of XBP1 mRNA]; 4-phenylbutyric acid inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of XBP1 protein alternative form]; 4-phenylbutyric acid inhibits the reaction [titanium dioxide results in increased expression of XBP1 protein alternative form]; 4-phenylbutyric acid inhibits the reaction [titanium dioxide results in increased splicing of XBP1 mRNA] 4-phenylbutyric acid results in decreased expression of XBP1 protein alternative form
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CTD |
PMID:20165829 PMID:23274897 PMID:25295624 PMID:27578021 PMID:27638906 PMID:28245985 PMID:29444456 PMID:30602124 PMID:30796460 PMID:31298478 PMID:33651226 PMID:33771661 PMID:34214594 PMID:35413383 PMID:36670177 PMID:37692514 More...
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NCBI chr14:84,604,623...84,609,707
Ensembl chr14:84,604,107...84,609,706
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G
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Xpo5
|
exportin 5
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decreases expression
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ISO
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4-phenylbutyric acid results in decreased expression of XPO5 mRNA
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CTD |
PMID:14583596 |
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NCBI chr 9:22,237,760...22,275,745
Ensembl chr 9:22,237,760...22,275,745
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G
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Ythdf2
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YTH N6-methyladenosine RNA binding protein F2
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decreases expression
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ISO
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4-phenylbutyric acid results in decreased expression of YTHDF2 mRNA
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CTD |
PMID:14583596 |
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NCBI chr 5:149,665,467...149,693,127
Ensembl chr 5:149,665,325...149,689,941
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G
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Zbtb2
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zinc finger and BTB domain containing 2
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decreases expression
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ISO
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4-phenylbutyric acid results in decreased expression of ZBTB2 mRNA
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CTD |
PMID:14583596 |
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NCBI chr 1:43,232,839...43,252,115
Ensembl chr 1:43,232,839...43,252,614
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