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ONTOLOGY REPORT - ANNOTATIONS


Term:auraptene
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Accession:CHEBI:134355 term browser browse the term
Definition:A member of the class of coumarins that is umbelliferone in which the phenolic hydrogen has been replaced by a geranyl group. Ii is isolated from several edible fruits and vegetables and exhibits a variety of therapeutic properties.
Synonyms:exact_synonym: 7-{[(2E)-3,7-dimethylocta-2,6-dien-1-yl]oxy}-2H-1-benzopyran-2-one
 related_synonym: (E)-7-((3,7-Dimethylocta-2,6-dien-1-yl)oxy)-2H-chromen-2-one;   7-O-geranylumbelliferone;   7-geranyloxycoumarin;   Formula=C19H22O3;   InChI=1S/C19H22O3/c1-14(2)5-4-6-15(3)11-12-21-17-9-7-16-8-10-19(20)22-18(16)13-17/h5,7-11,13H,4,6,12H2,1-3H3/b15-11+;   InChIKey=RSDDHGSKLOSQFK-RVDMUPIBSA-N;   SMILES=C12=CC(=CC=C1C=CC(O2)=O)OC/C=C(/CCC=C(C)C)\\C
 xref: CAS:495-02-3;   Chemspider:1267148;   HMDB:HMDB0034054;   KNApSAcK:C00029763
 xref_mesh: MESH:C105832
 xref: PMID:10426794;   PMID:10820092;   PMID:10840935;   PMID:10890030;   PMID:10919638;   PMID:11023542;   PMID:13155117;   PMID:15218316;   PMID:16012713;   PMID:16317159;   PMID:16395701;   PMID:16979634;   PMID:17151446;   PMID:17284254;   PMID:17301064;   PMID:17571970;   PMID:17898489;   PMID:18060855;   PMID:18444171;   PMID:19276534;   PMID:19444820;   PMID:19640308;   PMID:19688830;   PMID:20460732;   PMID:20681532;   PMID:20702762;   PMID:20863601;   PMID:20955144;   PMID:21705169;   PMID:21911903;   PMID:22038981;   PMID:22283649;   PMID:22471969;   PMID:22742512;   PMID:22754300;   PMID:22761031;   PMID:23083450;   PMID:23219792;   PMID:23320178;   PMID:23368941;   PMID:23495198;   PMID:23872723;   PMID:24070132;   PMID:24955102;   PMID:25147119;   PMID:25522543;   PMID:25620131;   PMID:25810889;   PMID:26351512;   PMID:26474388;   PMID:26730337;   PMID:26944297;   PMID:27130820;   PMID:27207438;   PMID:27420975;   PMID:27763495;   PMID:27771936;   PMID:28383142;   PMID:9247600;   PMID:9395216;   PMID:9525276;   PMID:9635577;   Reaxys:1291239;   Wikipedia:Auraptene


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auraptene term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcb1a ATP binding cassette subfamily B member 1A JBrowse link 4 22,339,829 22,517,642 RGD:6480464
G Ccna2 cyclin A2 JBrowse link 2 123,274,727 123,282,266 RGD:6480464
G Ccnb2 cyclin B2 JBrowse link 8 76,847,972 76,861,165 RGD:6480464
G Cdc45 cell division cycle 45 JBrowse link 11 86,328,785 86,354,099 RGD:6480464
G Cdk1 cyclin-dependent kinase 1 JBrowse link 20 20,576,341 20,591,510 RGD:6480464
G Cdkn2b cyclin-dependent kinase inhibitor 2B JBrowse link 5 107,834,353 107,857,428 RGD:6480464
G Cdkn2c cyclin-dependent kinase inhibitor 2C JBrowse link 5 129,347,731 129,352,886 RGD:6480464
G Chek1 checkpoint kinase 1 JBrowse link 8 39,181,162 39,201,588 RGD:6480464
G Chek2 checkpoint kinase 2 JBrowse link 12 51,845,574 51,878,098 RGD:6480464
G Ctnnb1 catenin beta 1 JBrowse link 8 129,601,511 129,628,378 RGD:6480464
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 JBrowse link 8 62,472,087 62,478,122 RGD:6480464
G Ddit3 DNA-damage inducible transcript 3 JBrowse link 7 70,578,564 70,585,074 RGD:6480464
G Dusp1 dual specificity phosphatase 1 JBrowse link 10 16,970,642 16,973,425 RGD:6480464
G E2f1 E2F transcription factor 1 JBrowse link 3 150,062,895 150,073,721 RGD:6480464
G E2f2 E2F transcription factor 2 JBrowse link 5 154,516,611 154,540,228 RGD:6480464
G Gadd45a growth arrest and DNA-damage-inducible, alpha JBrowse link 4 97,782,512 97,784,814 RGD:6480464
G Jun Jun proto-oncogene, AP-1 transcription factor subunit JBrowse link 5 114,011,184 114,014,277 RGD:6480464
G Kif20b kinesin family member 20B JBrowse link 1 253,220,038 253,275,523 RGD:6480464
G Mcm3 minichromosome maintenance complex component 3 JBrowse link 9 26,914,057 26,932,201 RGD:6480464
G Mcm6 minichromosome maintenance complex component 6 JBrowse link 13 45,042,882 45,068,073 RGD:6480464
G Nfe2l2 nuclear factor, erythroid 2-like 2 JBrowse link 3 62,497,568 62,525,146 RGD:6480464
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:6480464
G Uhrf1 ubiquitin-like with PHD and ring finger domains 1 JBrowse link 9 10,738,211 10,758,403 RGD:6480464
G Vegfa vascular endothelial growth factor A JBrowse link 9 17,340,341 17,355,681 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19789
    role 19735
      chemical role 19268
        antioxidant 14223
          auraptene 24
Path 2
Term Annotations click to browse term
  CHEBI ontology 19789
    subatomic particle 19787
      composite particle 19787
        hadron 19787
          baryon 19787
            nucleon 19787
              atomic nucleus 19787
                atom 19787
                  main group element atom 19672
                    p-block element atom 19672
                      carbon group element atom 19569
                        carbon atom 19558
                          organic molecular entity 19558
                            organic molecule 19480
                              organic cyclic compound 19239
                                organic heterocyclic compound 18352
                                  oxacycle 17132
                                    benzopyran 9474
                                      1-benzopyran 9169
                                        chromenes 910
                                          chromenone 833
                                            coumarins 551
                                              hydroxycoumarin 299
                                                umbelliferone 79
                                                  auraptene 24
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.