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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

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Accession:CHEBI:132050 term browser browse the term
Definition:A racemate comprising equimolar amounts of (R)- and (S)-norverapamil. The major active metabolite of verapamil.
Synonyms:exact_synonym: rac-2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl]amino}-2-(propan-2-yl)pentanenitrile
 related_synonym: (RS)-2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl]amino}-2-(propan-2-yl)pentanenitrile;   (RS)-norverapamil;   5-((3,4-Dimethoxyphenethyl)amino)-2-(3,4-dimethoxyphenyl)-2-isopropylvaleronitrile;   Formula=C26H36N2O4;   alpha-(3-((2-(3,4-Dimethoxyphenyl)ethyl)amino)propyl)-3,4-dimethoxy-alpha-(1-methylethyl)benzeneacetonitrile;   desmethylverapamil;   rac-norverapamil
 xref: CAS:67018-85-3;   Chemspider:94724;   HMDB:HMDB0060540
 xref_mesh: MESH:C016904
 xref: PMID:10336579;   PMID:10613599;   PMID:10701911;   PMID:11377051;   PMID:11456122;   PMID:11777750;   PMID:11996822;   PMID:12016885;   PMID:15563760;   PMID:15918524;   PMID:16013069;   PMID:16892180;   PMID:17981422;   PMID:18193210;   PMID:18806964;   PMID:19746412;   PMID:19898809;   PMID:20166433;   PMID:20604832;   PMID:21135265;   PMID:22300394;   PMID:22677487;   PMID:23757929;   PMID:23916407;   PMID:24044638;   PMID:24532601;   PMID:25237334;   PMID:25571292;   PMID:25650380;   PMID:26265240;   PMID:26643325;   PMID:27457673;   PMID:27750166;   PMID:8554934;   PMID:9572542;   PMID:9613945;   Reaxys:5458977;   Wikipedia:Norverapamil

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norverapamil term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 decreases activity ISO norverapamil results in decreased activity of CYP3A5 protein CTD PMID:15689501 NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422
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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19821
    role 19769
      biological role 19769
        xenobiotic 18452
          norverapamil 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19821
    subatomic particle 19819
      composite particle 19819
        hadron 19819
          baryon 19819
            nucleon 19819
              atomic nucleus 19819
                atom 19819
                  main group element atom 19716
                    main group molecular entity 19716
                      s-block molecular entity 19502
                        hydrogen molecular entity 19498
                          hydrides 18852
                            inorganic hydride 17691
                              pnictogen hydride 17672
                                nitrogen hydride 17545
                                  azane 17279
                                    ammonia 17278
                                      organic amino compound 17278
                                        secondary amino compound 6583
                                          2-(3,4-dimethoxyphenyl)-5-\{[2-(3,4-dimethoxyphenyl)ethyl]amino\}-2-(propan-2-yl)pentanenitrile 1
                                            (R)-norverapamil 1
                                              norverapamil 1
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