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ONTOLOGY REPORT - ANNOTATIONS
Term:cyclothiazide
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Accession:CHEBI:31448 term browser browse the term
Definition:3,4-Dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide substituted at positions 3, 5 and 6 by a 2-norbornen-5-yl group, chlorine, and a sulfonamide group, respectively. A thiazide diuretic, it has been used in the management of hypertension and oedema.
Synonyms:exact_synonym: 3-(bicyclo[2.2.1]hept-5-en-2-yl)-6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
 related_synonym: 6-chloro-3,4-dihydro-3-(2-norbornen-5-yl)-7-sulfamoyl-1,2,4-benzothiadiazine 1,1-dioxide;   6-chloro-3,4-dihydro-3-(5-norbornen-2-yl)-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide;   6-chloro-3-(2-norbornen-5-yl)-7-sulfamyl-3,4-dihydro-1,2,4-benzothiadiazine 1,1-dioxide;   Formula=C14H16ClN3O4S2;   InChI=1S/C14H16ClN3O4S2/c15-10-5-11-13(6-12(10)23(16,19)20)24(21,22)18-14(17-11)9-4-7-1-2-8(9)3-7/h1-2,5-9,14,17-18H,3-4H2,(H2,16,19,20);   InChIKey=BOCUKUHCLICSIY-UHFFFAOYSA-N;   SMILES=NS(=O)(=O)c1cc2c(NC(NS2(=O)=O)C2CC3CC2C=C3)cc1Cl;   ciclotiazida;   cyclothiazidum
 alt_id: CHEBI:47361;   CHEBI:598653
 xref: Beilstein:722843 "Beilstein";   CAS:2259-96-3 "ChemIDplus";   CAS:2259-96-3 "KEGG COMPOUND";   CAS:2259-96-3 "NIST Chemistry WebBook";   DrugBank:DB00606;   Drug_Central:761 "DrugCentral";   KEGG:C12685;   KEGG:D01256;   LINCS:LSM-4421
 xref_mesh: MESH:C004639
 xref: PDBeChem:CYZ;   PMID:19338354 "ChEMBL";   Patent:US3275625;   Wikipedia:Cyclothiazide

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cyclothiazide term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Sfrp4 secreted frizzled-related protein 4 JBrowse link 17 47,383,983 47,394,065 RGD:6480464
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19657
    role 19601
      application 19225
        pharmaceutical 19089
          drug 19089
            diuretic 968
              cyclothiazide 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19657
    subatomic particle 19653
      composite particle 19653
        hadron 19653
          baryon 19653
            nucleon 19653
              atomic nucleus 19653
                atom 19653
                  main group element atom 19534
                    p-block element atom 19534
                      carbon group element atom 19417
                        carbon atom 19409
                          organic molecular entity 19409
                            organic molecule 19332
                              organic cyclic compound 19083
                                organic heterocyclic compound 18154
                                  organonitrogen heterocyclic compound 16967
                                    thiazide 74
                                      benzothiadiazine 74
                                        cyclothiazide 1
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