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ONTOLOGY REPORT - ANNOTATIONS


Term:bevantolol
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Accession:CHEBI:238698 term browser browse the term
Definition:A propanolamine that is 3-aminopropane-1,2-diol in which the hydrogen of the primary hydroxy group is substituted by 3-methylphenyl and one of the hydrogens attached to the nitrogen is substituted by 2-(3,4-dimethoxyphenyl)ethyl. A beta1 adrenoceptor antagonist, it has been shown to be as effective as other beta-blockers for the treatment of angina pectoris and hypertension.
Synonyms:exact_synonym: 1-{[2-(3,4-dimethoxyphenyl)ethyl]amino}-3-(3-methylphenoxy)propan-2-ol
 related_synonym: 1-((2-(3,4-dimethoxyphenyl)ethyl)amino)-3-(3-methylphenoxy)-2-propanol;   1-(3,4-dimethoxyphenethylamino)-3-(m-tolyloxy)-2-propanol;   1-(3,4-dimethoxyphenethylamino)-3-m-tolyloxy-propan-2-ol;   1-[2-(3,4-Dimethoxy-phenyl)-ethylamino]-3-m-tolyloxy-propan-2-ol;   Formula=C20H27NO4;   InChI=1S/C20H27NO4/c1-15-5-4-6-18(11-15)25-14-17(22)13-21-10-9-16-7-8-19(23-2)20(12-16)24-3/h4-8,11-12,17,21-22H,9-10,13-14H2,1-3H3;   InChIKey=HXLAFSUPPDYFEO-UHFFFAOYSA-N;   SMILES=COc1ccc(CCNCC(O)COc2cccc(C)c2)cc1OC;   bevantololum
 xref: Beilstein:2769444 "Beilstein";   CAS:59170-23-9 "ChemIDplus";   DrugBank:DB01295;   Drug_Central:360 "DrugCentral"
 xref_mesh: MESH:C021148
 xref: PMID:2871781 "Europe PMC";   PMID:2894292 "Europe PMC";   Patent:BE790165;   Patent:US3857891;   Patent:US4994618;   Reaxys:2769444 "Reaxys"


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bevantolol term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adrb1 adrenoceptor beta 1 JBrowse link 1 277,537,585 277,538,985 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19669
    role 19613
      application 19235
        pharmaceutical 19097
          drug 19097
            cardiovascular drug 7550
              anti-arrhythmia drug 872
                bevantolol 1
                  (R)-bevantolol 0
                  (S)-bevantolol 0
                  bevantolol hydrochloride + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19669
    subatomic particle 19665
      composite particle 19665
        hadron 19665
          baryon 19665
            nucleon 19665
              atomic nucleus 19665
                atom 19665
                  main group element atom 19545
                    main group molecular entity 19545
                      s-block molecular entity 19329
                        hydrogen molecular entity 19319
                          hydrides 18242
                            inorganic hydride 17104
                              pnictogen hydride 17062
                                nitrogen hydride 16885
                                  azane 16564
                                    ammonia 16561
                                      organic amino compound 16560
                                        amino alcohol 860
                                          propanolamine 164
                                            bevantolol 1
                                              (R)-bevantolol 0
                                              (S)-bevantolol 0
                                              bevantolol hydrochloride + 0
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