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Accession:CHEBI:74838 term browser browse the term
Definition:An organic heterotricyclic compound resulting from the formal condensation of the oxo group of cytidine to the 2' position with loss of water to give the corresponding cyclic ether. A prodrug, it is metabolised to the antineoplastic agent cytarabine, so is used to maintain a more constant antineoplastic action.
Synonyms:exact_synonym: (2R,3R,3aS,9aR)-2-(hydroxymethyl)-6-imino-2,3,3a,9a-tetrahydro-6H-furo[2',3':4,5][1,3]oxazolo[3,2-a]pyrimidin-3-ol
 related_synonym: 2,2'-O-cyclocytidine;   2,2'-anhydro-1-(beta-D-arabinofuranosyl)cytosine;   2,2'-anhydro-AraC;   2,2'-anhydroarabinosylcytosine;   2,2'-anhydrocytidine;   2,2'-cyclocytidine;   Formula=C9H11N3O4;   InChI=1S/C9H11N3O4/c10-5-1-2-12-8-7(16-9(12)11-5)6(14)4(3-13)15-8/h1-2,4,6-8,10,13-14H,3H2/t4-,6-,7+,8-/m1/s1;   InChIKey=BBDAGFIXKZCXAH-CCXZUQQUSA-N;   SMILES=OC[C@H]1O[C@@H]2[C@@H](Oc3nc(=N)ccn23)[C@@H]1O;   [2R-(2alpha,3beta,3abeta,9abeta)]-2,3,3a,9a-tetrahydro-3-hydroxy-6-imino-6H-furo[2',3':4,5]pxazolo[3,2-a]pyrimidine-2-methanol;   ancitabina;   ancitabinum;   anhydrocytidine;   cyclocytidine
 xref: CAS:31698-14-3;   Drug_Central:212
 xref_mesh: MESH:D003504
 xref: PMID:6204036;   PMID:6206222;   PMID:77191;   Patent:US3463850;   Reaxys:669322
 cyclic_relationship: is_conjugate_base_of CHEBI:74842

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ancitabine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mthfr methylenetetrahydrofolate reductase JBrowse link 5 164,844,642 164,864,360 RGD:6480464
G Timp3 TIMP metallopeptidase inhibitor 3 JBrowse link 7 23,543,125 23,594,170 RGD:6480464

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  CHEBI ontology 19758
    role 19705
      biological role 19704
        biochemical role 19206
          antimetabolite 8493
            ancitabine 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19758
    subatomic particle 19756
      composite particle 19756
        hadron 19756
          baryon 19756
            nucleon 19756
              atomic nucleus 19756
                atom 19756
                  main group element atom 19641
                    p-block element atom 19641
                      carbon group element atom 19532
                        carbon atom 19521
                          organic molecular entity 19521
                            organic molecule 19441
                              organic cyclic compound 19203
                                organic heterocyclic compound 18278
                                  organic heteropolycyclic compound 17585
                                    organic heterotricyclic compound 13750
                                      ancitabine 2
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