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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:D-glucopyranose
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Accession:CHEBI:4167 term browser browse the term
Definition:A glucopyranose having D-configuration.
Synonyms:related_synonym: D-Glc;   D-Glcp;   D-Glucose;   Dextrose;   Formula=C6H12O6;   Glc-OH;   Grape sugar;   InChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6?/m1/s1;   InChIKey=WQZGKKKJIJFFOK-GASJEMHNSA-N;   SMILES=OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O;   WURCS=2.0/1,1,0/[a2122h-1x_1-5]/1/;   glucose
 xref: Beilstein:1281604;   CAS:2280-44-6;   GlyGen:G15021LG;   GlyTouCan:G15021LG;   Gmelin:83256;   HMDB:HMDB0000122;   KEGG:C00031;   KEGG:D00009;   KNApSAcK:C00001122;   MetaCyc:D-Glucose;   PMID:15987845;   PMID:16901854;   PMID:17336832;   PMID:17439666;   PMID:17928662;   PMID:19913595;   PMID:26812026;   PMID:32619908;   PMID:7524207;   PMID:9140037;   PMID:9501190;   PMID:9506998;   PMID:9545565;   Reaxys:1281604;   Wikipedia:Glucose


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(+)-syringaresinol beta-D-glucoside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACHE acetylcholinesterase (Yt blood group) multiple interactions ISO acanthoside B inhibits the reaction [Scopolamine results in increased expression of ACHE protein] CTD PMID:31077737 NCBI chr 7:100,889,994...100,896,994
Ensembl chr 7:100,889,994...100,896,974 		JBrowse link
G BDNF brain derived neurotrophic factor multiple interactions ISO [acanthoside B co-treated with Scopolamine] results in increased expression of BDNF protein CTD PMID:31077737 NCBI chr11:27,654,893...27,722,030
Ensembl chr11:27,654,893...27,722,058 		JBrowse link
G CAT catalase multiple interactions ISO acanthoside B inhibits the reaction [Scopolamine results in decreased activity of CAT protein] CTD PMID:31077737 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060 		JBrowse link
G CREB1 cAMP responsive element binding protein 1 multiple interactions ISO acanthoside B inhibits the reaction [Scopolamine results in decreased phosphorylation of CREB1 protein] CTD PMID:31077737 NCBI chr 2:207,529,962...207,605,988
Ensembl chr 2:207,529,737...207,605,988 		JBrowse link
G IL10 interleukin 10 multiple interactions ISO acanthoside B inhibits the reaction [Scopolamine results in decreased expression of IL10 protein] CTD PMID:31077737 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541 		JBrowse link
G IL1B interleukin 1 beta multiple interactions ISO acanthoside B inhibits the reaction [Scopolamine results in increased expression of IL1B protein] CTD PMID:31077737 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL6 interleukin 6 multiple interactions ISO acanthoside B inhibits the reaction [Scopolamine results in increased expression of IL6 protein] CTD PMID:31077737 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G NOS2 nitric oxide synthase 2 multiple interactions ISO acanthoside B inhibits the reaction [Scopolamine results in increased expression of NOS2 protein] CTD PMID:31077737 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529 		JBrowse link
G NTRK2 neurotrophic receptor tyrosine kinase 2 multiple interactions ISO [acanthoside B co-treated with Scopolamine] results in increased phosphorylation of NTRK2 protein CTD PMID:31077737 NCBI chr 9:84,668,522...85,027,054
Ensembl chr 9:84,668,375...85,095,751 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO acanthoside B inhibits the reaction [Scopolamine results in increased expression of PTGS2 protein] CTD PMID:31077737 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922 		JBrowse link
G TNF tumor necrosis factor multiple interactions ISO acanthoside B inhibits the reaction [Scopolamine results in increased expression of TNF protein] CTD PMID:31077737 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
(20S)-ginsenoside Rh1 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FOS Fos proto-oncogene, AP-1 transcription factor subunit increases expression EXP ginsenoside Rh1 results in increased expression of FOS mRNA CTD PMID:16204943 NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,282,230 		JBrowse link
G ICAM1 intercellular adhesion molecule 1 multiple interactions EXP ginsenoside Rh1 inhibits the reaction [TNF protein results in increased expression of ICAM1 protein] CTD PMID:21875580 NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615 		JBrowse link
G IL1B interleukin 1 beta multiple interactions ISO ginsenoside Rh1 inhibits the reaction [Oxazolone results in increased expression of IL1B mRNA]; ginsenoside Rh1 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1B mRNA] CTD PMID:16557482 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL4 interleukin 4 decreases expression ISO ginsenoside Rh1 results in decreased expression of IL4 CTD PMID:22855946 NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678 		JBrowse link
G IL6 interleukin 6 multiple interactions EXP ginsenoside Rh1 inhibits the reaction [Galactose results in increased secretion of IL6 protein] CTD PMID:29412148 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G ITGA4 integrin subunit alpha 4 multiple interactions EXP ginsenoside Rh1 inhibits the reaction [TNF protein results in increased expression of [ITGA4 protein binds to ITGB1 protein]] CTD PMID:21875580 NCBI chr 2:181,457,205...181,538,940
Ensembl chr 2:181,457,202...181,538,940 		JBrowse link
G ITGAL integrin subunit alpha L multiple interactions EXP ginsenoside Rh1 inhibits the reaction [TNF protein results in increased expression of [ITGAL protein binds to ITGB2 protein]] CTD PMID:21875580 NCBI chr16:30,472,742...30,523,185
Ensembl chr16:30,472,658...30,523,567 		JBrowse link
G ITGB1 integrin subunit beta 1 multiple interactions EXP ginsenoside Rh1 inhibits the reaction [TNF protein results in increased expression of [ITGA4 protein binds to ITGB1 protein]] CTD PMID:21875580 NCBI chr10:32,900,318...32,958,230
Ensembl chr10:32,887,273...33,005,792 		JBrowse link
G ITGB2 integrin subunit beta 2 multiple interactions EXP ginsenoside Rh1 inhibits the reaction [TNF protein results in increased expression of [ITGAL protein binds to ITGB2 protein]] CTD PMID:21875580 NCBI chr21:44,885,953...44,928,815
Ensembl chr21:44,885,953...44,931,989 		JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit decreases activity ISO ginsenoside Rh1 results in decreased activity of JUN protein CTD PMID:22855946 NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,776,845...58,784,048 		JBrowse link
G LPL lipoprotein lipase increases secretion ISO ginsenoside Rh1 results in increased secretion of LPL protein CTD PMID:8988629 NCBI chr 8:19,939,253...19,967,259
Ensembl chr 8:19,901,717...19,967,259 		JBrowse link
G PGR progesterone receptor increases expression EXP ginsenoside Rh1 results in increased expression of PGR protein CTD PMID:16204943 NCBI chr11:101,029,624...101,129,813
Ensembl chr11:101,029,624...101,129,813 		JBrowse link
G PPARG peroxisome proliferator activated receptor gamma multiple interactions ISO ginsenoside Rh1 inhibits the reaction [bisphenol A results in increased expression of PPARG mRNA]; ginsenoside Rh1 inhibits the reaction [bisphenol A results in increased expression of PPARG protein] CTD PMID:32623698 NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO ginsenoside Rh1 inhibits the reaction [Oxazolone results in increased expression of PTGS2 mRNA]; ginsenoside Rh1 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA] CTD PMID:16557482 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922 		JBrowse link
G SELE selectin E multiple interactions EXP ginsenoside Rh1 inhibits the reaction [TNF protein results in increased expression of SELE protein] CTD PMID:21875580 NCBI chr 1:169,722,640...169,734,079
Ensembl chr 1:169,722,640...169,764,705 		JBrowse link
G TFF1 trefoil factor 1 increases expression EXP ginsenoside Rh1 results in increased expression of TFF1 mRNA CTD PMID:16204943 NCBI chr21:42,362,282...42,366,535
Ensembl chr21:42,362,282...42,366,535 		JBrowse link
G TNF tumor necrosis factor multiple interactions
decreases response to substance
decreases expression		 ISO
EXP		 ginsenoside Rh1 inhibits the reaction [Oxazolone results in increased expression of TNF mRNA]; ginsenoside Rh1 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF mRNA]
ginsenoside Rh1 results in decreased susceptibility to TNF protein
ginsenoside Rh1 inhibits the reaction [TNF protein results in increased expression of [ITGA4 protein binds to ITGB1 protein]]; ginsenoside Rh1 inhibits the reaction [TNF protein results in increased expression of [ITGAL protein binds to ITGB2 protein]]; ginsenoside Rh1 inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]; ginsenoside Rh1 inhibits the reaction [TNF protein results in increased expression of SELE protein]; ginsenoside Rh1 inhibits the reaction [TNF protein results in increased expression of VCAM1 protein]
ginsenoside Rh1 results in decreased expression of TNF		 CTD PMID:16557482 PMID:21875580 PMID:22855946 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G VCAM1 vascular cell adhesion molecule 1 multiple interactions EXP ginsenoside Rh1 inhibits the reaction [TNF protein results in increased expression of VCAM1 protein] CTD PMID:21875580 NCBI chr 1:100,719,742...100,739,045
Ensembl chr 1:100,719,742...100,739,045 		JBrowse link
(20S)-ginsenoside Rh2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKT1 AKT serine/threonine kinase 1 decreases phosphorylation EXP ginsenoside Rh2 results in decreased phosphorylation of AKT1 protein CTD PMID:32762018 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,759 		JBrowse link
G BAX BCL2 associated X, apoptosis regulator increases expression EXP ginsenoside Rh2 results in increased expression of BAX protein CTD PMID:26482938 PMID:32762018 NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798 		JBrowse link
G BCL2 BCL2 apoptosis regulator decreases expression EXP ginsenoside Rh2 results in decreased expression of BCL2 protein CTD PMID:26482938 PMID:32762018 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128 		JBrowse link
G CASP3 caspase 3 increases cleavage
decreases expression		 EXP ginsenoside Rh2 results in increased cleavage of CASP3 protein
ginsenoside Rh2 results in decreased expression of CASP3 protein		 CTD PMID:26482938 PMID:32762018 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062 		JBrowse link
G CASP9 caspase 9 decreases expression EXP ginsenoside Rh2 results in decreased expression of CASP9 protein CTD PMID:32762018 NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534 		JBrowse link
G CCND1 cyclin D1 decreases expression EXP ginsenoside Rh2 results in decreased expression of CCND1 protein CTD PMID:26482938 NCBI chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474 		JBrowse link
G HDAC1 histone deacetylase 1 decreases expression EXP ginsenoside Rh2 results in decreased expression of HDAC1 protein CTD PMID:26482938 NCBI chr 1:32,292,083...32,333,626
Ensembl chr 1:32,292,083...32,333,635 		JBrowse link
G HDAC2 histone deacetylase 2 decreases expression EXP ginsenoside Rh2 results in decreased expression of HDAC2 protein CTD PMID:26482938 NCBI chr 6:113,933,028...113,971,148
Ensembl chr 6:113,933,028...114,011,308 		JBrowse link
G HDAC6 histone deacetylase 6 decreases expression EXP ginsenoside Rh2 results in decreased expression of HDAC6 protein CTD PMID:26482938 NCBI chr  X:48,801,398...48,824,982
Ensembl chr  X:48,801,377...48,824,982 		JBrowse link
G IL6 interleukin 6 multiple interactions EXP ginsenoside Rh2 inhibits the reaction [Galactose results in increased secretion of IL6 protein] CTD PMID:29412148 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 decreases phosphorylation
increases phosphorylation		 EXP ginsenoside Rh2 results in decreased phosphorylation of MAPK1 protein
ginsenoside Rh2 results in increased phosphorylation of MAPK1 protein		 CTD PMID:26482938 PMID:32762018 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 decreases phosphorylation
increases phosphorylation		 EXP ginsenoside Rh2 results in decreased phosphorylation of MAPK3 protein
ginsenoside Rh2 results in increased phosphorylation of MAPK3 protein		 CTD PMID:26482938 PMID:32762018 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506 		JBrowse link
G MTOR mechanistic target of rapamycin kinase decreases phosphorylation EXP ginsenoside Rh2 results in decreased phosphorylation of MTOR protein CTD PMID:32762018 NCBI chr 1:11,106,535...11,262,551
Ensembl chr 1:11,106,535...11,262,556 		JBrowse link
G NFKBIA NFKB inhibitor alpha increases expression EXP ginsenoside Rh2 results in increased expression of NFKBIA protein CTD PMID:32762018 NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit multiple interactions EXP ginsenoside Rh2 results in increased expression of and results in decreased phosphorylation of RELA protein CTD PMID:32762018 NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090 		JBrowse link
(R)-amygdalin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACTA2 actin alpha 2, smooth muscle multiple interactions EXP
ISO		 Amygdalin inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 mRNA]; Amygdalin inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 protein] CTD PMID:36457260 NCBI chr10:88,935,074...88,991,337
Ensembl chr10:88,934,822...88,991,339 		JBrowse link
G FN1 fibronectin 1 multiple interactions ISO
EXP		 Amygdalin inhibits the reaction [TGFB1 protein results in increased expression of FN1 mRNA]; Amygdalin inhibits the reaction [TGFB1 protein results in increased expression of FN1 protein] CTD PMID:36457260 NCBI chr 2:215,360,865...215,436,068
Ensembl chr 2:215,360,440...215,436,073 		JBrowse link
G HPSE heparanase multiple interactions ISO
EXP		 Amygdalin inhibits the reaction [Ovalbumin results in increased expression of HPSE protein]; Amygdalin inhibits the reaction [TGFB1 protein results in increased expression of HPSE protein] CTD PMID:36457260 NCBI chr 4:83,292,461...83,335,153
Ensembl chr 4:83,292,461...83,335,153 		JBrowse link
G PTGS1 prostaglandin-endoperoxide synthase 1 multiple interactions EXP [peoniflorin co-treated with benzoylpaeoniflorin co-treated with Amygdalin] inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS1 mRNA]; Amygdalin inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS1 mRNA] CTD PMID:33149750 NCBI chr 9:122,370,533...122,395,703
Ensembl chr 9:122,370,530...122,395,703 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP [peoniflorin co-treated with benzoylpaeoniflorin co-treated with Amygdalin] inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; Amygdalin inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA] CTD PMID:33149750 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922 		JBrowse link
G TGFB1 transforming growth factor beta 1 multiple interactions ISO
EXP		 Amygdalin inhibits the reaction [Ovalbumin results in increased secretion of TGFB1 protein]; Amygdalin inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 mRNA]; Amygdalin inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 protein]; Amygdalin inhibits the reaction [TGFB1 protein results in increased expression of FN1 mRNA]; Amygdalin inhibits the reaction [TGFB1 protein results in increased expression of FN1 protein]; Amygdalin inhibits the reaction [TGFB1 protein results in increased expression of HPSE protein]; Amygdalin inhibits the reaction [TGFB1 protein results in increased expression of VIM mRNA]; Amygdalin inhibits the reaction [TGFB1 protein results in increased expression of VIM protein]; Amygdalin inhibits the reaction [TGFB1 protein results in increased secretion of TGFB1 protein] CTD PMID:36457260 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922 		JBrowse link
G VIM vimentin multiple interactions ISO
EXP		 Amygdalin inhibits the reaction [TGFB1 protein results in increased expression of VIM mRNA]; Amygdalin inhibits the reaction [TGFB1 protein results in increased expression of VIM protein] CTD PMID:36457260 NCBI chr10:17,228,241...17,237,593
Ensembl chr10:17,228,241...17,237,593 		JBrowse link
2-amino-2-deoxy-D-glucopyranose term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AACS acetoacetyl-CoA synthetase increases expression ISO Glucosamine results in increased expression of AACS mRNA CTD PMID:17178593 NCBI chr12:125,065,435...125,143,316
Ensembl chr12:125,065,434...125,143,333 		JBrowse link
G ABCG1 ATP binding cassette subfamily G member 1 increases expression ISO Glucosamine results in increased expression of ABCG1 mRNA CTD PMID:17109745 NCBI chr21:42,199,689...42,297,244
Ensembl chr21:42,199,689...42,297,244 		JBrowse link
G ACACA acetyl-CoA carboxylase alpha increases expression EXP Glucosamine results in increased expression of ACACA mRNA CTD PMID:22096489 NCBI chr17:37,084,992...37,406,836
Ensembl chr17:37,084,992...37,406,836 		JBrowse link
G ACAN aggrecan multiple interactions
increases expression
decreases expression
affects expression		 EXP
ISO		 Glucosamine analog affects the reaction [IL1B results in decreased expression of ACAN mRNA]; Glucosamine inhibits the reaction [IL1B protein results in decreased expression of ACAN mRNA]; Glucosamine results in decreased cleavage of and results in decreased secretion of ACAN protein
Glucosamine results in increased expression of ACAN mRNA
Glucosamine inhibits the reaction [IL1B results in decreased expression of ACAN mRNA]
Glucosamine analog results in increased expression of ACAN protein; Glucosamine results in increased expression of ACAN mRNA; Glucosamine results in increased expression of ACAN protein
Glucosamine analog results in decreased expression of ACAN mRNA
Glucosamine analog affects the expression of ACAN mRNA		 CTD PMID:12801482 PMID:16300972 PMID:16872674 PMID:17109745 PMID:17337215 More... NCBI chr15:88,803,436...88,875,353
Ensembl chr15:88,803,436...88,875,353 		JBrowse link
G ACOT1 acyl-CoA thioesterase 1 increases expression ISO Glucosamine results in increased expression of ACOT1 mRNA CTD PMID:17178593 NCBI chr14:73,490,933...73,543,796
Ensembl chr14:73,537,143...73,543,796 		JBrowse link
G ACOX2 acyl-CoA oxidase 2 decreases expression ISO Glucosamine results in decreased expression of ACOX2 mRNA CTD PMID:17178593 NCBI chr 3:58,505,136...58,537,190
Ensembl chr 3:58,505,136...58,537,283 		JBrowse link
G ACSS2 acyl-CoA synthetase short chain family member 2 increases expression ISO Glucosamine results in increased expression of ACSS2 mRNA CTD PMID:17178593 NCBI chr20:34,874,989...34,927,959
Ensembl chr20:34,872,146...34,927,962 		JBrowse link
G ADAM15 ADAM metallopeptidase domain 15 multiple interactions
decreases expression		 ISO Glucosamine affects the reaction [IL1B results in decreased expression of ADAM15 mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of ADAM15 mRNA] CTD PMID:17109745 NCBI chr 1:155,051,316...155,062,775
Ensembl chr 1:155,050,566...155,062,775 		JBrowse link
G ADAM17 ADAM metallopeptidase domain 17 multiple interactions
increases expression		 ISO Glucosamine inhibits the reaction [IL1B results in increased expression of ADAM17 mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of ADAM17 mRNA] CTD PMID:17109745 NCBI chr 2:9,488,486...9,555,830
Ensembl chr 2:9,488,486...9,556,732 		JBrowse link
G ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif 1 decreases expression
multiple interactions		 EXP
ISO		 Glucosamine analog results in decreased expression of ADAMTS1 mRNA
Glucosamine results in decreased expression of ADAMTS1 mRNA
Glucosamine inhibits the reaction [IL1B results in increased expression of ADAMTS1 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of ADAMTS1 mRNA]		 CTD PMID:16300972 PMID:17109745 NCBI chr21:26,835,755...26,845,409
Ensembl chr21:26,835,755...26,845,409 		JBrowse link
G ADAMTS20 ADAM metallopeptidase with thrombospondin type 1 motif 20 decreases cleavage EXP Glucosamine results in decreased cleavage of ADAMTS20 protein alternative form CTD PMID:19909832 NCBI chr12:43,352,763...43,552,203
Ensembl chr12:43,353,866...43,552,203 		JBrowse link
G ADAMTS4 ADAM metallopeptidase with thrombospondin type 1 motif 4 increases expression ISO Glucosamine results in increased expression of ADAMTS4 mRNA CTD PMID:17109745 NCBI chr 1:161,184,302...161,199,054
Ensembl chr 1:161,184,302...161,199,054 		JBrowse link
G ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif 5 decreases expression
multiple interactions		 EXP Glucosamine analog results in decreased expression of ADAMTS5 mRNA
Glucosamine results in decreased cleavage of and results in decreased activity of ADAMTS5 protein alternative form		 CTD PMID:16300972 PMID:19909832 NCBI chr21:26,917,922...26,967,088
Ensembl chr21:26,917,922...26,967,088 		JBrowse link
G ADAMTS9 ADAM metallopeptidase with thrombospondin type 1 motif 9 decreases cleavage EXP Glucosamine results in decreased cleavage of ADAMTS9 protein alternative form CTD PMID:19909832 NCBI chr 3:64,515,654...64,688,000
Ensembl chr 3:64,515,654...64,688,000 		JBrowse link
G ADIPOQ adiponectin, C1Q and collagen domain containing increases expression ISO Glucosamine results in increased expression of ADIPOQ mRNA CTD PMID:15694357 NCBI chr 3:186,842,710...186,858,463
Ensembl chr 3:186,842,704...186,858,463 		JBrowse link
G AFP alpha fetoprotein increases expression ISO Glucosamine results in increased expression of AFP mRNA CTD PMID:17178593 NCBI chr 4:73,436,221...73,456,174
Ensembl chr 4:73,431,138...73,456,174 		JBrowse link
G AGT angiotensinogen increases expression ISO Glucosamine results in increased expression of AGT mRNA CTD PMID:17178593 NCBI chr 1:230,702,523...230,745,583
Ensembl chr 1:230,690,776...230,745,576 		JBrowse link
G AHI1 Abelson helper integration site 1 decreases expression ISO Glucosamine results in decreased expression of AHI1 mRNA CTD PMID:17178593 NCBI chr 6:135,283,532...135,497,740
Ensembl chr 6:135,283,407...135,498,434 		JBrowse link
G AKT1 AKT serine/threonine kinase 1 affects phosphorylation
multiple interactions		 EXP
ISO		 Glucosamine analog affects the phosphorylation of AKT1 protein
Glucosamine inhibits the reaction [INS1 protein results in increased phosphorylation of AKT1 protein]; OSTN protein affects the reaction [Glucosamine inhibits the reaction [INS1 protein results in increased phosphorylation of AKT1 protein]]
Glucosamine analog affects the reaction [IL1B results in increased phosphorylation of AKT1 protein]; Glucosamine promotes the reaction [IL1B results in increased phosphorylation of AKT1 protein]		 CTD PMID:18080321 PMID:18340449 PMID:30602124 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,759 		JBrowse link
G ALB albumin multiple interactions ISO [LEPR protein affects the susceptibility to Glucosamine] which affects the expression of ALB protein CTD PMID:33345901 NCBI chr 4:73,404,287...73,421,482
Ensembl chr 4:73,397,114...73,421,482 		JBrowse link
G ALG12 ALG12 alpha-1,6-mannosyltransferase decreases expression ISO Glucosamine results in decreased expression of ALG12 mRNA CTD PMID:17178593 NCBI chr22:49,859,311...49,918,438
Ensembl chr22:49,900,229...49,918,438 		JBrowse link
G ALPL alkaline phosphatase, biomineralization associated multiple interactions
increases expression
increases activity		 EXP 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [Glucosamine analog results in increased activity of ALPL protein]
Glucosamine analog results in increased expression of ALPL mRNA		 CTD PMID:20458730 NCBI chr 1:21,508,984...21,578,410
Ensembl chr 1:21,509,397...21,578,410 		JBrowse link
G APOA1 apolipoprotein A1 increases secretion
increases stability		 EXP Glucosamine results in increased secretion of APOA1 protein
Glucosamine results in increased stability of APOA1 mRNA		 CTD PMID:15164326 NCBI chr11:116,835,751...116,837,950
Ensembl chr11:116,835,751...116,837,622 		JBrowse link
G APOB apolipoprotein B multiple interactions
increases degradation
increases ubiquitination
decreases secretion
decreases localization
decreases expression		 EXP
ISO		 acetylleucyl-leucyl-norleucinal inhibits the reaction [Glucosamine results in decreased expression of and results in decreased secretion of APOB protein]; Glucosamine results in decreased expression of and results in decreased secretion of APOB protein; Oleic Acid inhibits the reaction [Glucosamine results in decreased secretion of APOB protein]
Oleic Acid inhibits the reaction [Glucosamine results in increased degradation of APOB protein]
Glucosamine results in increased ubiquitination of APOB protein
Glucosamine results in decreased localization of APOB protein
Glucosamine results in decreased expression of APOB protein		 CTD PMID:15618547 PMID:19383982 NCBI chr 2:21,001,429...21,044,073
Ensembl chr 2:21,001,429...21,044,073 		JBrowse link
G APOE apolipoprotein E multiple interactions ISO [Streptozocin co-treated with APOE mutant form] results in increased abundance of Glucosamine; INS1 inhibits the reaction [[Streptozocin co-treated with APOE mutant form] results in increased abundance of Glucosamine] CTD PMID:16380481 NCBI chr19:44,905,796...44,909,393
Ensembl chr19:44,905,791...44,909,393 		JBrowse link
G ASS1 argininosuccinate synthase 1 multiple interactions ISO Glucosamine inhibits the reaction [IL1B results in increased expression of ASS1 mRNA] CTD PMID:17109745 NCBI chr 9:130,444,707...130,501,274
Ensembl chr 9:130,444,961...130,501,274 		JBrowse link
G ATF3 activating transcription factor 3 decreases expression ISO Glucosamine results in decreased expression of ATF3 mRNA CTD PMID:17178593 NCBI chr 1:212,565,407...212,620,777
Ensembl chr 1:212,565,334...212,620,777 		JBrowse link
G ATF4 activating transcription factor 4 increases expression
multiple interactions		 ISO
EXP		 Glucosamine results in increased expression of ATF4 mRNA; Glucosamine results in increased expression of ATF4 protein
NUS1 protein inhibits the reaction [Glucosamine results in increased expression of ATF4 mRNA]
4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of ATF4 mRNA]; 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of ATF4 protein]; EIF2AK3 protein affects the reaction [Glucosamine results in increased expression of ATF4 mRNA]; GSK2656157 inhibits the reaction [Glucosamine results in increased expression of ATF4 mRNA]		 CTD PMID:30602124 PMID:33812996 NCBI chr22:39,520,559...39,522,686
Ensembl chr22:39,519,695...39,522,683 		JBrowse link
G ATF6 activating transcription factor 6 multiple interactions
increases expression
decreases expression		 EXP
ISO		 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of ATF6 mRNA]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of MEF2A mRNA]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of MEF2A protein]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of PPARGC1A mRNA]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of PPARGC1A protein]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of SLC2A4 mRNA]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of SLC2A4 protein]; NUS1 protein inhibits the reaction [Glucosamine results in increased expression of ATF6 mRNA]; ursodoxicoltaurine inhibits the reaction [Glucosamine results in increased expression of ATF6 mRNA]
Glucosamine results in increased expression of ATF6 protein
ATF6 protein affects the reaction [Glucosamine results in increased expression of OSTN mRNA]
4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of ATF6 mRNA]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of MEF2A mRNA]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of MEF2A protein]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of PPARGC1A mRNA]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of PPARGC1A protein]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of SLC2A4 mRNA]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of SLC2A4 protein]; ursodoxicoltaurine inhibits the reaction [Glucosamine results in increased expression of ATF6 mRNA]
Glucosamine results in decreased expression of ATF6 mRNA		 CTD PMID:17178593 PMID:19383982 PMID:20165829 PMID:30602124 PMID:33812996 NCBI chr 1:161,766,320...161,964,070
Ensembl chr 1:161,766,298...161,977,574 		JBrowse link
G ATF7IP activating transcription factor 7 interacting protein increases expression ISO Glucosamine results in increased expression of ATF7IP mRNA CTD PMID:17178593 NCBI chr12:14,365,682...14,502,930
Ensembl chr12:14,365,676...14,502,931 		JBrowse link
G ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 decreases expression ISO Glucosamine results in decreased expression of ATP2A2 mRNA CTD PMID:17178593 NCBI chr12:110,280,616...110,351,093
Ensembl chr12:110,280,756...110,351,093 		JBrowse link
G AZIN1 antizyme inhibitor 1 decreases expression
multiple interactions		 ISO Glucosamine results in decreased expression of AZIN1 mRNA
IL1B promotes the reaction [Glucosamine results in increased expression of AZIN1 mRNA]		 CTD PMID:17109745 NCBI chr 8:102,826,302...102,864,200
Ensembl chr 8:102,826,111...102,893,864 		JBrowse link
G B3GAT3 beta-1,3-glucuronyltransferase 3 multiple interactions
increases expression		 ISO [XDH protein co-treated with Hypoxanthine] inhibits the reaction [Glucosamine results in increased expression of B3GAT3 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in decreased activity of B3GAT3 protein]; Glucosamine inhibits the reaction [IL1B protein results in decreased expression of B3GAT3 mRNA] CTD PMID:11229466 PMID:11801247 NCBI chr11:62,615,296...62,621,986
Ensembl chr11:62,615,296...62,622,154 		JBrowse link
G BCL2L1 BCL2 like 1 decreases expression
multiple interactions		 EXP Glucosamine results in decreased expression of BCL2L1 protein
pepstatin inhibits the reaction [Glucosamine results in decreased expression of BCL2L1 protein]		 CTD PMID:15972124 PMID:16850161 NCBI chr20:31,664,452...31,723,963
Ensembl chr20:31,664,452...31,723,989 		JBrowse link
G BDNF brain derived neurotrophic factor decreases expression ISO Glucosamine results in decreased expression of BDNF mRNA CTD PMID:17178593 NCBI chr11:27,654,893...27,722,030
Ensembl chr11:27,654,893...27,722,058 		JBrowse link
G BGLAP bone gamma-carboxyglutamate protein increases expression EXP Glucosamine analog results in increased expression of BGLAP mRNA CTD PMID:20458730 NCBI chr 1:156,242,184...156,243,317
Ensembl chr 1:156,242,184...156,243,317 		JBrowse link
G BGN biglycan multiple interactions
decreases expression		 ISO Glucosamine inhibits the reaction [IL1B results in increased expression of BGN mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of BGN mRNA] CTD PMID:17109745 NCBI chr  X:153,494,980...153,509,546
Ensembl chr  X:153,494,980...153,509,546 		JBrowse link
G BMAL1 basic helix-loop-helix ARNT like 1 decreases expression ISO Glucosamine results in decreased expression of BMAL1 mRNA; Glucosamine results in decreased expression of BMAL1 protein CTD PMID:24442997 NCBI chr11:13,276,652...13,387,266
Ensembl chr11:13,276,652...13,387,266 		JBrowse link
G BMP2 bone morphogenetic protein 2 multiple interactions ISO Glucosamine inhibits the reaction [IL1B results in increased expression of BMP2 mRNA] CTD PMID:17109745 NCBI chr20:6,767,686...6,780,246
Ensembl chr20:6,767,686...6,780,246 		JBrowse link
G BMP4 bone morphogenetic protein 4 decreases expression
multiple interactions		 ISO Glucosamine results in decreased expression of BMP4 mRNA
Glucosamine promotes the reaction [IL1B results in decreased expression of BMP4 mRNA]		 CTD PMID:17109745 NCBI chr14:53,949,736...53,956,891
Ensembl chr14:53,949,736...53,958,761 		JBrowse link
G BMP6 bone morphogenetic protein 6 multiple interactions
decreases expression		 ISO Glucosamine inhibits the reaction [IL1B results in increased expression of BMP6 mRNA]
Glucosamine results in decreased expression of BMP6 mRNA		 CTD PMID:17109745 NCBI chr 6:7,726,099...7,881,728
Ensembl chr 6:7,726,099...7,881,728 		JBrowse link
G BMP7 bone morphogenetic protein 7 multiple interactions
increases expression		 ISO Glucosamine inhibits the reaction [IL1B results in increased expression of BMP7 mRNA]
Glucosamine results in increased expression of BMP7 mRNA		 CTD PMID:17109745 NCBI chr20:57,168,753...57,266,641
Ensembl chr20:57,168,753...57,266,641 		JBrowse link
G CA3 carbonic anhydrase 3 decreases expression ISO Glucosamine results in decreased expression of CAR3 mRNA CTD PMID:17109745 NCBI chr 8:85,438,859...85,449,040
Ensembl chr 8:85,373,436...85,449,040 		JBrowse link
G CALR calreticulin decreases expression ISO Glucosamine results in decreased expression of CALR mRNA CTD PMID:17178593 NCBI chr19:12,938,609...12,944,489
Ensembl chr19:12,938,578...12,944,489 		JBrowse link
G CASP3 caspase 3 increases cleavage
multiple interactions		 EXP Glucosamine results in increased cleavage of CASP3 protein
Glucosamine results in increased activity of and results in increased cleavage of CASP3 protein		 CTD PMID:16850161 PMID:22020377 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062 		JBrowse link
G CASP4 caspase 4 decreases expression ISO Glucosamine results in decreased expression of CASP4 mRNA CTD PMID:17178593 NCBI chr11:104,942,866...104,968,574
Ensembl chr11:104,942,866...104,969,366 		JBrowse link
G CBR3 carbonyl reductase 3 increases expression ISO Glucosamine results in increased expression of CBR3 mRNA CTD PMID:17178593 NCBI chr21:36,135,079...36,146,562
Ensembl chr21:36,135,079...36,146,562 		JBrowse link
G CCL2 C-C motif chemokine ligand 2 multiple interactions
increases expression		 EXP
ISO		 Alloxan inhibits the reaction [Glucosamine inhibits the reaction [Cathelicidins results in increased expression of CCL2 protein]]; Glucosamine analog inhibits the reaction [IL1B results in increased secretion of CCL2 protein]; Glucosamine inhibits the reaction [Cathelicidins results in increased expression of CCL2 mRNA]; Glucosamine inhibits the reaction [Cathelicidins results in increased expression of CCL2 protein]; Glucosamine inhibits the reaction [TNF results in increased expression of CCL2 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of CCL2 protein]
Glucosamine results in increased expression of CCL2 mRNA
Glucosamine inhibits the reaction [IL1B results in increased expression of CCL2 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of CCL2 mRNA]		 CTD PMID:17109745 PMID:18080321 PMID:18949387 PMID:19020780 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208 		JBrowse link
G CCL20 C-C motif chemokine ligand 20 multiple interactions
increases expression		 ISO Glucosamine inhibits the reaction [IL1B results in increased expression of CCL20 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of CCL20 mRNA] CTD PMID:17109745 NCBI chr 2:227,813,842...227,817,556
Ensembl chr 2:227,805,739...227,817,564 		JBrowse link
G CCL22 C-C motif chemokine ligand 22 multiple interactions ISO Glucosamine inhibits the reaction [IL1B results in increased expression of CCL22 mRNA] CTD PMID:17109745 NCBI chr16:57,357,909...57,366,189
Ensembl chr16:57,358,783...57,366,189 		JBrowse link
G CCL3 C-C motif chemokine ligand 3 multiple interactions ISO Glucosamine inhibits the reaction [IL1B results in increased expression of CCL3 mRNA] CTD PMID:17109745 NCBI chr17:36,088,256...36,090,143
Ensembl chr17:36,088,256...36,090,169 		JBrowse link
G CCL5 C-C motif chemokine ligand 5 multiple interactions EXP
ISO		 Glucosamine analog inhibits the reaction [IL1B results in increased secretion of CCL5 protein]
Glucosamine inhibits the reaction [IL1B results in increased expression of CCL5 mRNA]		 CTD PMID:17109745 PMID:18080321 NCBI chr17:35,871,491...35,880,360
Ensembl chr17:35,871,491...35,880,793 		JBrowse link
G CCL7 C-C motif chemokine ligand 7 multiple interactions
increases expression		 ISO Glucosamine inhibits the reaction [IL1B results in increased expression of CCL7 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of CCL7 mRNA] CTD PMID:17109745 NCBI chr17:34,270,221...34,272,242
Ensembl chr17:34,270,221...34,272,242 		JBrowse link
G CCN2 cellular communication network factor 2 increases expression ISO Glucosamine analog results in increased expression of CCN2 mRNA CTD PMID:21466783 NCBI chr 6:131,948,176...131,951,372
Ensembl chr 6:131,948,176...131,951,372 		JBrowse link
G CCNB1 cyclin B1 decreases expression ISO Glucosamine results in decreased expression of CCNB1 mRNA CTD PMID:17109745 NCBI chr 5:69,167,150...69,178,245
Ensembl chr 5:69,167,135...69,178,245 		JBrowse link
G CD24 CD24 molecule increases expression ISO Glucosamine results in increased expression of CD24A mRNA CTD PMID:17178593 NCBI chr 6:106,969,831...106,976,855
Ensembl chr 6:106,969,831...106,975,627 		JBrowse link
G CD28 CD28 molecule increases expression ISO Glucosamine results in increased expression of CD28 mRNA CTD PMID:17109745 NCBI chr 2:203,706,482...203,738,912
Ensembl chr 2:203,706,475...203,738,912 		JBrowse link
G CDC20 cell division cycle 20 decreases expression ISO Glucosamine results in decreased expression of CDC20 mRNA CTD PMID:17109745 NCBI chr 1:43,358,981...43,363,203
Ensembl chr 1:43,358,981...43,363,203 		JBrowse link
G CDC23 cell division cycle 23 decreases expression ISO Glucosamine results in decreased expression of CDC23 mRNA CTD PMID:17109745 NCBI chr 5:138,187,650...138,213,323
Ensembl chr 5:138,187,650...138,213,343 		JBrowse link
G CDK1 cyclin dependent kinase 1 decreases expression ISO Glucosamine results in decreased expression of CDK1 mRNA CTD PMID:17109745 NCBI chr10:60,778,331...60,794,852
Ensembl chr10:60,778,331...60,794,852 		JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A increases expression ISO Glucosamine results in increased expression of CDKN1A protein
Glucosamine results in increased expression of CDKN1A mRNA		 CTD PMID:15654767 PMID:17178593 NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,337 		JBrowse link
G CDKN1B cyclin dependent kinase inhibitor 1B decreases expression ISO Glucosamine results in decreased expression of CDKN1B protein CTD PMID:15654767 NCBI chr12:12,717,368...12,722,369
Ensembl chr12:12,685,498...12,722,369 		JBrowse link
G CDKN3 cyclin dependent kinase inhibitor 3 decreases expression ISO Glucosamine results in decreased expression of CDKN3 mRNA CTD PMID:17109745 NCBI chr14:54,397,007...54,420,218
Ensembl chr14:54,396,849...54,420,218 		JBrowse link
G CENPF centromere protein F decreases expression ISO Glucosamine results in decreased expression of CENPF mRNA CTD PMID:17109745 NCBI chr 1:214,603,195...214,664,571
Ensembl chr 1:214,603,185...214,664,574 		JBrowse link
G CHI3L1 chitinase 3 like 1 decreases expression EXP Glucosamine analog results in decreased expression of CHI3L1 mRNA CTD PMID:16142878 NCBI chr 1:203,178,931...203,186,704
Ensembl chr 1:203,178,931...203,186,704 		JBrowse link
G CHUK component of inhibitor of nuclear factor kappa B kinase complex multiple interactions
decreases activity		 EXP Glucosamine analog results in decreased activity of and results in decreased localization of CHUK protein
Glucosamine analog results in decreased activity of CHUK protein		 CTD PMID:20113495 NCBI chr10:100,186,319...100,229,596
Ensembl chr10:100,188,300...100,229,596 		JBrowse link
G CKAP2 cytoskeleton associated protein 2 decreases expression ISO Glucosamine results in decreased expression of CKAP2 mRNA CTD PMID:17109745 NCBI chr13:52,455,478...52,476,627
Ensembl chr13:52,455,429...52,476,628 		JBrowse link
G CLOCK clock circadian regulator decreases expression ISO Glucosamine results in decreased expression of CLOCK mRNA; Glucosamine results in decreased expression of CLOCK protein CTD PMID:24442997 NCBI chr 4:55,427,903...55,546,909
Ensembl chr 4:55,427,903...55,546,909 		JBrowse link
G CLTA clathrin light chain A decreases expression ISO Glucosamine results in decreased expression of CLTA mRNA CTD PMID:17109745 NCBI chr 9:36,190,874...36,212,059
Ensembl chr 9:36,190,856...36,304,781 		JBrowse link
G COL11A1 collagen type XI alpha 1 chain multiple interactions
decreases expression		 ISO Glucosamine inhibits the reaction [IL1B results in decreased expression of COL11A1 mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of COL11A1 mRNA] CTD PMID:17109745 NCBI chr 1:102,876,473...103,108,522
Ensembl chr 1:102,876,467...103,108,872 		JBrowse link
G COL1A1 collagen type I alpha 1 chain multiple interactions
decreases expression		 EXP Glucosamine inhibits the reaction [IL1B protein results in increased expression of COL1A1 mRNA]
Glucosamine results in decreased expression of COL1A1 mRNA		 CTD PMID:18321735 NCBI chr17:50,184,101...50,201,631
Ensembl chr17:50,184,101...50,201,632 		JBrowse link
G COL2A1 collagen type II alpha 1 chain multiple interactions
affects expression
increases expression		 EXP
ISO		 Glucosamine analog affects the reaction [IL1B results in decreased expression of COL2A1 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in decreased expression of COL2A1 mRNA]
Glucosamine inhibits the reaction [IL1B results in decreased expression of COL2A1 mRNA]
Glucosamine analog affects the expression of COL2A1 mRNA
Glucosamine analog results in increased expression of COL2A1 mRNA; Glucosamine results in increased expression of COL2A1 mRNA		 CTD PMID:16300972 PMID:17109745 PMID:17337215 PMID:18321735 NCBI chr12:47,972,967...48,006,212
Ensembl chr12:47,972,967...48,004,554 		JBrowse link
G COL3A1 collagen type III alpha 1 chain multiple interactions ISO Glucosamine inhibits the reaction [IL1B results in decreased expression of COL3A1 mRNA] CTD PMID:17109745 NCBI chr 2:188,974,373...189,012,746
Ensembl chr 2:188,974,373...189,012,746 		JBrowse link
G COL8A1 collagen type VIII alpha 1 chain multiple interactions
decreases expression		 ISO Glucosamine inhibits the reaction [IL1B results in increased expression of COL8A1 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of COL8A1 mRNA] CTD PMID:17109745 NCBI chr 3:99,638,594...99,799,217
Ensembl chr 3:99,638,475...99,799,226 		JBrowse link
G CSF1 colony stimulating factor 1 multiple interactions
decreases expression		 ISO Glucosamine inhibits the reaction [IL1B results in increased expression of CSF1 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of CSF1 mRNA] CTD PMID:17109745 NCBI chr 1:109,910,506...109,930,992
Ensembl chr 1:109,910,242...109,930,992 		JBrowse link
G CSF2 colony stimulating factor 2 multiple interactions
increases expression		 ISO Glucosamine inhibits the reaction [IL1B results in increased expression of CSF2 mRNA]
Glucosamine results in increased expression of CSF2 mRNA		 CTD PMID:17109745 NCBI chr 5:132,073,789...132,076,170
Ensembl chr 5:132,073,789...132,076,170 		JBrowse link
G CSF3 colony stimulating factor 3 multiple interactions
increases expression		 ISO Glucosamine inhibits the reaction [IL1B results in increased expression of CSF3 mRNA]
Glucosamine results in increased expression of CSF3 mRNA		 CTD PMID:17109745 NCBI chr17:40,015,440...40,017,813
Ensembl chr17:40,015,361...40,017,813 		JBrowse link
G CTSD cathepsin D affects localization
multiple interactions
increases activity
decreases expression		 EXP Glucosamine affects the localization of CTSD protein
pepstatin inhibits the reaction [Glucosamine results in decreased expression of CTSD protein alternative form]
Glucosamine results in increased activity of CTSD protein		 CTD PMID:15972124 PMID:16850161 NCBI chr11:1,752,755...1,763,927
Ensembl chr11:1,752,752...1,764,573 		JBrowse link
G CUL2 cullin 2 multiple interactions EXP Glucosamine analog inhibits the reaction [TNF results in increased expression of CUL2 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of CUL2 mRNA] CTD PMID:18173918 NCBI chr10:35,008,551...35,127,006
Ensembl chr10:35,008,504...35,127,006 		JBrowse link
G CXCL1 C-X-C motif chemokine ligand 1 multiple interactions
increases expression
decreases expression		 ISO Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL1 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of CXCL1 mRNA]
Glucosamine results in increased expression of CXCL3 mRNA
Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL3 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of CXCL3 mRNA]		 CTD PMID:17109745 NCBI chr 4:73,869,393...73,871,308
Ensembl chr 4:73,869,393...73,871,308 		JBrowse link
G CXCL10 C-X-C motif chemokine ligand 10 multiple interactions ISO Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL10 mRNA]
Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL10 mRNA]		 CTD PMID:17109745 PMID:20737476 NCBI chr 4:76,021,118...76,023,497
Ensembl chr 4:76,021,118...76,023,497 		JBrowse link
G CXCL11 C-X-C motif chemokine ligand 11 multiple interactions ISO Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL11 mRNA] CTD PMID:17109745 NCBI chr 4:76,033,682...76,036,070
Ensembl chr 4:76,033,682...76,041,415 		JBrowse link
G CXCL12 C-X-C motif chemokine ligand 12 multiple interactions
decreases expression		 ISO Glucosamine promotes the reaction [IL1B results in decreased expression of CXCL12 mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of CXCL12 mRNA] CTD PMID:17109745 NCBI chr10:44,370,165...44,385,097
Ensembl chr10:44,370,165...44,386,493 		JBrowse link
G CXCL2 C-X-C motif chemokine ligand 2 multiple interactions
increases expression		 ISO Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL2 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of CXCL2 mRNA] CTD PMID:17109745 NCBI chr 4:74,097,040...74,099,195
Ensembl chr 4:74,097,040...74,099,196 		JBrowse link
G CXCL6 C-X-C motif chemokine ligand 6 multiple interactions ISO Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL5 mRNA] CTD PMID:17109745 NCBI chr 4:73,836,678...73,838,760
Ensembl chr 4:73,836,640...73,849,064 		JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 multiple interactions EXP Glucosamine analog inhibits the reaction [IL1B results in increased expression of CXCL8 mRNA]; Glucosamine analog inhibits the reaction [IL1B results in increased secretion of CXCL8 protein]; Glucosamine analog inhibits the reaction [TNF results in increased expression of CXCL8 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL8 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL8 protein]; Glucosamine inhibits the reaction [IL1B results in increased secretion of CXCL8 protein]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased secretion of CXCL8 protein]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL8 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of CXCL8 mRNA] CTD PMID:18026701 PMID:18080321 PMID:19626664 PMID:20113495 PMID:20307528 NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716 		JBrowse link
G CYBA cytochrome b-245 alpha chain decreases expression EXP Glucosamine results in decreased expression of CYBA mRNA CTD PMID:18077487 NCBI chr16:88,643,289...88,651,053
Ensembl chr16:88,643,275...88,651,083 		JBrowse link
G CYCS cytochrome c, somatic affects localization EXP Glucosamine affects the localization of CYCS protein CTD PMID:15972124 PMID:22020377 NCBI chr 7:25,118,656...25,125,260
Ensembl chr 7:25,118,656...25,125,260 		JBrowse link
G CYP51A1 cytochrome P450 family 51 subfamily A member 1 increases expression ISO Glucosamine results in increased expression of CYP51 mRNA CTD PMID:17178593 NCBI chr 7:92,112,153...92,134,803
Ensembl chr 7:92,084,987...92,134,803 		JBrowse link
G DBI diazepam binding inhibitor, acyl-CoA binding protein increases expression ISO Glucosamine results in increased expression of DBI mRNA CTD PMID:17178593 NCBI chr 2:119,366,977...119,372,543
Ensembl chr 2:119,366,924...119,372,550 		JBrowse link
G DDIT3 DNA damage inducible transcript 3 increases expression
multiple interactions
decreases expression		 EXP
ISO		 Glucosamine results in increased expression of DDIT3 mRNA; Glucosamine results in increased expression of DDIT3 protein
NUS1 protein inhibits the reaction [Glucosamine results in increased expression of DDIT3 mRNA]
4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of DDIT3 mRNA]; 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of DDIT3 protein]
Glucosamine results in decreased expression of DDIT3 mRNA		 CTD PMID:16380481 PMID:17178593 PMID:30602124 PMID:33812996 NCBI chr12:57,516,588...57,520,517
Ensembl chr12:57,516,588...57,521,737 		JBrowse link
G DDIT4L DNA damage inducible transcript 4 like increases expression ISO Glucosamine results in increased expression of DDIT4L mRNA CTD PMID:17109745 NCBI chr 4:100,185,870...100,190,468
Ensembl chr 4:100,185,870...100,190,782 		JBrowse link
G DHCR7 7-dehydrocholesterol reductase increases expression ISO Glucosamine results in increased expression of DHCR7 mRNA CTD PMID:17178593 NCBI chr11:71,434,411...71,448,393
Ensembl chr11:71,428,193...71,452,868 		JBrowse link
G DNAJB11 DnaJ heat shock protein family (Hsp40) member B11 decreases expression ISO Glucosamine results in decreased expression of DNAJB11 mRNA CTD PMID:17178593 NCBI chr 3:186,570,720...186,585,793
Ensembl chr 3:186,567,403...186,585,800 		JBrowse link
G DNAJB9 DnaJ heat shock protein family (Hsp40) member B9 decreases expression ISO Glucosamine results in decreased expression of DNAJB9 mRNA CTD PMID:17178593 NCBI chr 7:108,569,874...108,574,850
Ensembl chr 7:108,569,867...108,574,850 		JBrowse link
G DNAJC3 DnaJ heat shock protein family (Hsp40) member C3 decreases expression ISO Glucosamine results in decreased expression of DNAJC3 mRNA CTD PMID:17178593 NCBI chr13:95,677,139...95,794,988
Ensembl chr13:95,677,139...95,794,988 		JBrowse link
G DSPP dentin sialophosphoprotein decreases expression EXP Glucosamine analog results in decreased expression of DSPP mRNA CTD PMID:20458730 NCBI chr 4:87,608,529...87,616,873
Ensembl chr 4:87,608,529...87,616,873 		JBrowse link
G DUSP5 dual specificity phosphatase 5 multiple interactions
increases expression		 ISO Glucosamine inhibits the reaction [IL1B results in increased expression of DUSP5 mRNA]
Glucosamine results in increased expression of DUSP5 mRNA		 CTD PMID:17109745 NCBI chr10:110,497,907...110,511,533
Ensembl chr10:110,497,907...110,511,533 		JBrowse link
G DUSP7 dual specificity phosphatase 7 multiple interactions
decreases expression		 ISO Glucosamine inhibits the reaction [IL1B results in increased expression of DUSP7 mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of DUSP7 mRNA] CTD PMID:17109745 NCBI chr 3:52,048,919...52,056,571
Ensembl chr 3:52,048,919...52,056,571 		JBrowse link
G DYNC1I1 dynein cytoplasmic 1 intermediate chain 1 decreases expression ISO Glucosamine results in decreased expression of DYNC1I1 mRNA CTD PMID:17109745 NCBI chr 7:95,772,554...96,110,322
Ensembl chr 7:95,772,506...96,110,322 		JBrowse link
G EDEM1 ER degradation enhancing alpha-mannosidase like protein 1 decreases expression ISO Glucosamine results in decreased expression of EDEM1 mRNA CTD PMID:17178593 NCBI chr 3:5,187,707...5,219,958
Ensembl chr 3:5,187,646...5,219,958 		JBrowse link
G EIF2AK3 eukaryotic translation initiation factor 2 alpha kinase 3 multiple interactions
increases expression
increases phosphorylation		 ISO
EXP		 EIF2AK3 gene mutant form inhibits the reaction [Glucosamine results in increased phosphorylation of EIF2S1 protein]
NUS1 protein inhibits the reaction [Glucosamine results in increased expression of EIF2AK3 protein]
EIF2AK3 protein affects the reaction [Glucosamine results in increased expression of ATF4 mRNA]; EIF2AK3 protein affects the reaction [Glucosamine results in increased expression of OSTN mRNA]; EIF2AK3 protein affects the reaction [Glucosamine results in increased phosphorylation of EIF2S1 protein]
Glucosamine results in increased phosphorylation of EIF2AK3 protein		 CTD PMID:16324875 PMID:19383982 PMID:30602124 PMID:33812996 NCBI chr 2:88,556,741...88,628,145
Ensembl chr 2:88,556,741...88,691,518 		JBrowse link
G EIF2S1 eukaryotic translation initiation factor 2 subunit alpha increases phosphorylation
multiple interactions		 EXP
ISO		 Glucosamine results in increased phosphorylation of EIF2S1 protein
NUS1 protein inhibits the reaction [Glucosamine results in increased phosphorylation of EIF2S1 protein]
4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased phosphorylation of EIF2S1 protein]; EIF2AK3 protein affects the reaction [Glucosamine results in increased phosphorylation of EIF2S1 protein]; GSK2656157 inhibits the reaction [Glucosamine results in increased phosphorylation of EIF2S1 protein]
EIF2AK3 gene mutant form inhibits the reaction [Glucosamine results in increased phosphorylation of EIF2S1 protein]		 CTD PMID:16324875 PMID:19383982 PMID:30602124 PMID:33812996 NCBI chr14:67,360,328...67,386,516
Ensembl chr14:67,360,328...67,386,516 		JBrowse link
G ELOVL6 ELOVL fatty acid elongase 6 increases expression ISO Glucosamine results in increased expression of ELOVL6 mRNA CTD PMID:17178593 NCBI chr 4:110,045,846...110,199,202
Ensembl chr 4:110,045,846...110,199,199 		JBrowse link
G EPAS1 endothelial PAS domain protein 1 decreases expression
multiple interactions		 ISO Glucosamine results in decreased expression of EPAS1 mRNA
Glucosamine inhibits the reaction [IL1B results in increased expression of EPAS1 mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of EPAS1 mRNA]		 CTD PMID:17109745 NCBI chr 2:46,297,407...46,386,697
Ensembl chr 2:46,293,667...46,386,697 		JBrowse link
G EPRS1 glutamyl-prolyl-tRNA synthetase 1 decreases expression ISO Glucosamine results in decreased expression of EPRS1 mRNA CTD PMID:17178593 NCBI chr 1:219,968,600...220,046,505
Ensembl chr 1:219,968,600...220,046,530 		JBrowse link
G ERN1 endoplasmic reticulum to nucleus signaling 1 multiple interactions
increases expression		 ISO
EXP		 ERN1 protein affects the reaction [Glucosamine results in increased expression of OSTN mRNA]; ERN1 protein affects the reaction [Glucosamine results in increased splicing of XBP1 mRNA]
Glucosamine results in increased expression of ERN1 mRNA
NUS1 protein inhibits the reaction [Glucosamine results in increased expression of ERN1 mRNA]		 CTD PMID:30602124 PMID:33812996 NCBI chr17:64,039,142...64,130,144
Ensembl chr17:64,039,080...64,130,819 		JBrowse link
G FABP4 fatty acid binding protein 4 increases expression ISO Glucosamine results in increased expression of FABP4 mRNA CTD PMID:15694357 NCBI chr 8:81,478,419...81,483,233
Ensembl chr 8:81,478,419...81,483,236 		JBrowse link
G FASN fatty acid synthase increases expression EXP Glucosamine results in increased expression of FASN mRNA CTD PMID:22096489 NCBI chr17:82,078,338...82,098,236
Ensembl chr17:82,078,338...82,098,294 		JBrowse link
G FBP2 fructose-bisphosphatase 2 increases expression ISO Glucosamine results in increased expression of FBP2 mRNA CTD PMID:17178593 NCBI chr 9:94,558,720...94,593,824
Ensembl chr 9:94,558,720...94,593,824 		JBrowse link
G FGF2 fibroblast growth factor 2 multiple interactions ISO Glucosamine promotes the reaction [Glucose results in increased expression of FGF2 mRNA] CTD PMID:1518840 NCBI chr 4:122,826,682...122,898,236
Ensembl chr 4:122,826,682...122,898,236 		JBrowse link
G FGF7 fibroblast growth factor 7 decreases expression
multiple interactions		 ISO Glucosamine results in decreased expression of FGF7 mRNA
IL1B inhibits the reaction [Glucosamine results in decreased expression of FGF7 mRNA]		 CTD PMID:17109745 NCBI chr15:49,423,242...49,488,775
Ensembl chr15:49,423,237...49,488,775 		JBrowse link
G FGF9 fibroblast growth factor 9 multiple interactions
increases expression		 ISO Glucosamine inhibits the reaction [IL1B results in increased expression of FGF9 mRNA]
Glucosamine results in increased expression of FGF9 mRNA		 CTD PMID:17109745 NCBI chr13:21,671,073...21,704,498
Ensembl chr13:21,671,073...21,704,498 		JBrowse link
G FGFR1 fibroblast growth factor receptor 1 multiple interactions
increases expression		 ISO Glucosamine inhibits the reaction [IL1B results in decreased expression of FGFR1 mRNA]
Glucosamine results in increased expression of FGFR1 mRNA		 CTD PMID:17109745 NCBI chr 8:38,411,143...38,468,635
Ensembl chr 8:38,400,215...38,468,834 		JBrowse link
G FKBP11 FKBP prolyl isomerase 11 decreases expression ISO Glucosamine results in decreased expression of FKBP11 mRNA CTD PMID:17178593 NCBI chr12:48,921,963...48,939,034
Ensembl chr12:48,921,518...48,926,474 		JBrowse link
G FN1 fibronectin 1 decreases expression ISO Glucosamine results in decreased expression of FN1 protein CTD PMID:17178593 NCBI chr 2:215,360,865...215,436,068
Ensembl chr 2:215,360,440...215,436,073 		JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO
EXP		 Glucosamine analog inhibits the reaction [Buthionine Sulfoximine results in increased expression of FOS mRNA]
Glucosamine analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS protein]		 CTD PMID:19375915 PMID:21825963 NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,282,230 		JBrowse link
G FURIN furin, paired basic amino acid cleaving enzyme decreases cleavage
multiple interactions		 EXP Glucosamine results in decreased cleavage of FURIN protein alternative form
Glucosamine results in decreased glycosylation of and results in decreased activity of FURIN protein		 CTD PMID:19909832 NCBI chr15:90,868,588...90,883,457
Ensembl chr15:90,868,588...90,883,564 		JBrowse link
G FXYD2 FXYD domain containing ion transport regulator 2 increases expression ISO Glucosamine results in increased expression of FXYD2 mRNA CTD PMID:17109745 NCBI chr11:117,820,057...117,828,089
Ensembl chr11:117,800,844...117,828,698 		JBrowse link
G GATM glycine amidinotransferase decreases expression ISO Glucosamine results in decreased expression of GATM mRNA CTD PMID:17109745 NCBI chr15:45,361,124...45,402,227
Ensembl chr15:45,361,124...45,402,327 		JBrowse link
G GCK glucokinase decreases expression ISO Glucosamine results in decreased expression of GCK mRNA CTD PMID:11893929 NCBI chr 7:44,143,213...44,189,439
Ensembl chr 7:44,143,213...44,198,170 		JBrowse link
G GCLC glutamate-cysteine ligase catalytic subunit increases expression ISO Glucosamine analog results in increased expression of GCLC mRNA CTD PMID:21825963 NCBI chr 6:53,497,341...53,545,101
Ensembl chr 6:53,497,341...53,616,970 		JBrowse link
G GFPT1 glutamine--fructose-6-phosphate transaminase 1 multiple interactions ISO [Glucosamine co-treated with INS1 protein] affects the localization of GFPT1 protein CTD PMID:9453242 NCBI chr 2:69,319,780...69,387,227
Ensembl chr 2:69,319,780...69,387,250 		JBrowse link
G GLRX glutaredoxin increases expression ISO Glucosamine results in increased expression of GLRX mRNA CTD PMID:17178593 NCBI chr 5:95,813,849...95,822,726
Ensembl chr 5:95,751,319...95,822,726 		JBrowse link
G GNPNAT1 glucosamine-phosphate N-acetyltransferase 1 decreases expression ISO Glucosamine results in decreased expression of GNPNAT1 mRNA CTD PMID:17178593 NCBI chr14:52,775,193...52,791,607
Ensembl chr14:52,775,193...52,791,668 		JBrowse link
G GNPTAB N-acetylglucosamine-1-phosphate transferase subunits alpha and beta increases expression ISO Glucosamine results in increased expression of GNPTAB mRNA CTD PMID:17178593 NCBI chr12:101,745,499...101,830,959
Ensembl chr12:101,745,499...101,830,959 		JBrowse link
G GPD1L glycerol-3-phosphate dehydrogenase 1 like increases expression ISO Glucosamine results in increased expression of GPD1L mRNA CTD PMID:17178593 NCBI chr 3:32,106,620...32,168,709
Ensembl chr 3:32,105,689...32,168,709 		JBrowse link
G GREM1 gremlin 1, DAN family BMP antagonist multiple interactions
decreases expression		 ISO Glucosamine inhibits the reaction [IL1B results in increased expression of GREM1 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of GREM1 mRNA] CTD PMID:17109745 NCBI chr15:32,718,004...32,745,106
Ensembl chr15:32,718,004...32,745,106 		JBrowse link
G GSK3B glycogen synthase kinase 3 beta decreases phosphorylation
multiple interactions		 EXP Glucosamine results in decreased phosphorylation of GSK3B protein
Glucosamine inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]; NUS1 protein inhibits the reaction [Glucosamine inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]]; PRKAA1 protein promotes the reaction [Glucosamine inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]]; PRKAA1 protein promotes the reaction [NUS1 protein inhibits the reaction [Glucosamine inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]]]		 CTD PMID:33812996 NCBI chr 3:119,821,321...120,094,447
Ensembl chr 3:119,821,321...120,094,994 		JBrowse link
G GSPT1 G1 to S phase transition 1 multiple interactions EXP Glucosamine analog inhibits the reaction [TNF results in increased expression of GSPT1 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of GSPT1 mRNA] CTD PMID:18173918 NCBI chr16:11,868,128...11,916,654
Ensembl chr16:11,868,128...11,916,082 		JBrowse link
G GSTT1 glutathione S-transferase theta 1 increases expression ISO Glucosamine results in increased expression of GSTT1 mRNA CTD PMID:17178593
G HAPLN1 hyaluronan and proteoglycan link protein 1 decreases expression
multiple interactions		 ISO Glucosamine results in decreased expression of HAPLN1 mRNA
Glucosamine inhibits the reaction [IL1B results in decreased expression of HAPLN1 mRNA]; IL1B promotes the reaction [Glucosamine results in decreased expression of HAPLN1 mRNA]		 CTD PMID:17109745 NCBI chr 5:83,637,805...83,720,855
Ensembl chr 5:83,637,805...83,720,855 		JBrowse link
G HERPUD1 homocysteine inducible ER protein with ubiquitin like domain 1 decreases expression ISO Glucosamine results in decreased expression of HERPUD1 mRNA CTD PMID:17178593 NCBI chr16:56,932,142...56,944,864
Ensembl chr16:56,932,142...56,944,864 		JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha multiple interactions
decreases expression		 EXP Glucosamine affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HIF1A protein]; Glucosamine inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]
Glucosamine results in decreased expression of HIF1A mRNA; Glucosamine results in decreased expression of HIF1A protein		 CTD PMID:19254699 PMID:22020377 NCBI chr14:61,695,513...61,748,258
Ensembl chr14:61,695,513...61,748,259 		JBrowse link
G HK1 hexokinase 1 increases expression ISO Glucosamine results in increased expression of HK1 mRNA CTD PMID:11893929 PMID:17178593 NCBI chr10:69,270,000...69,401,882
Ensembl chr10:69,269,984...69,401,884 		JBrowse link
G HMGA1 high mobility group AT-hook 1 increases expression ISO Glucosamine results in increased expression of HMGA1 mRNA CTD PMID:17109745 NCBI chr 6:34,236,873...34,246,231
Ensembl chr 6:34,236,873...34,246,231 		JBrowse link
G HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 increases expression ISO Glucosamine results in increased expression of HMGCS1 mRNA CTD PMID:17178593 NCBI chr 5:43,287,470...43,313,412
Ensembl chr 5:43,287,470...43,313,512 		JBrowse link
G HMMR hyaluronan mediated motility receptor decreases expression ISO Glucosamine results in decreased expression of HMMR mRNA CTD PMID:17109745 NCBI chr 5:163,460,632...163,491,941
Ensembl chr 5:163,460,203...163,491,941 		JBrowse link
G HMOX1 heme oxygenase 1 multiple interactions
increases expression		 EXP Glucosamine inhibits the reaction [IL1B results in decreased expression of HMOX1 mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of HMOX1 protein]
Glucosamine results in increased expression of HMOX1 mRNA; Glucosamine results in increased expression of HMOX1 protein		 CTD PMID:18077487 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214 		JBrowse link
G HOXA1 homeobox A1 decreases expression ISO Glucosamine results in decreased expression of HOXA1 mRNA CTD PMID:17178593 NCBI chr 7:27,092,993...27,096,000
Ensembl chr 7:27,092,993...27,096,000 		JBrowse link
G HPGD 15-hydroxyprostaglandin dehydrogenase decreases expression ISO Glucosamine results in decreased expression of HPGD mRNA CTD PMID:17109745 NCBI chr 4:174,490,175...174,522,893
Ensembl chr 4:174,490,175...174,523,154 		JBrowse link
G HSP90B1 heat shock protein 90 beta family member 1 decreases expression
increases expression		 ISO
EXP		 Glucosamine results in decreased expression of HSP90B1 mRNA
Glucosamine results in increased expression of HSP90B1 protein		 CTD PMID:15618547 PMID:17109745 PMID:17178593 NCBI chr12:103,930,410...103,947,926
Ensembl chr12:103,930,107...103,953,931 		JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 multiple interactions
increases expression
decreases expression		 EXP
ISO		 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of HSPA5 mRNA]; NUS1 protein inhibits the reaction [Glucosamine results in increased expression of HSPA5 mRNA]; NUS1 protein inhibits the reaction [Glucosamine results in increased expression of HSPA5 protein]; ursodoxicoltaurine inhibits the reaction [Glucosamine results in increased expression of HSPA5 mRNA]
4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of HSPA5 mRNA]; 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of HSPA5 protein]
Glucosamine results in increased expression of HSPA5 mRNA; Glucosamine results in increased expression of HSPA5 protein
4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of HSPA5 mRNA]; ursodoxicoltaurine inhibits the reaction [Glucosamine results in increased expression of HSPA5 mRNA]
Glucosamine results in decreased expression of HSPA5 mRNA		 CTD PMID:15618547 PMID:16380481 PMID:17178593 PMID:19383982 PMID:20165829 More... NCBI chr 9:125,234,853...125,241,343
Ensembl chr 9:125,234,853...125,241,382 		JBrowse link
G HYOU1 hypoxia up-regulated 1 decreases expression ISO Glucosamine results in decreased expression of HYOU1 mRNA CTD PMID:17178593 NCBI chr11:119,044,188...119,057,205
Ensembl chr11:119,044,188...119,057,227 		JBrowse link
G ICAM1 intercellular adhesion molecule 1 multiple interactions
decreases activity		 EXP
ISO		 Alloxan inhibits the reaction [Glucosamine inhibits the reaction [Cathelicidins results in increased expression of ICAM1 protein]]; Glucosamine inhibits the reaction [[IL6 co-treated with TNF] results in increased expression of ICAM1 protein]; Glucosamine inhibits the reaction [Cathelicidins results in increased expression of ICAM1 mRNA]; Glucosamine inhibits the reaction [Cathelicidins results in increased expression of ICAM1 protein]; Glucosamine inhibits the reaction [IFNG promotes the reaction [TNF results in increased expression of ICAM1 protein]]; Glucosamine inhibits the reaction [IFNG results in increased expression of ICAM1 mRNA]; Glucosamine inhibits the reaction [IFNG results in increased expression of ICAM1 protein]; Glucosamine inhibits the reaction [IL1B promotes the reaction [TNF results in increased expression of ICAM1 protein]]; Glucosamine inhibits the reaction [IL1B results in increased expression of ICAM1 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of ICAM1 protein]; Glucosamine inhibits the reaction [IL6 results in increased expression of ICAM1 protein]; Glucosamine inhibits the reaction [TNF promotes the reaction [IFNG results in increased expression of ICAM1 protein]]; Glucosamine inhibits the reaction [TNF promotes the reaction [IL1B results in increased expression of ICAM1 protein]]; Glucosamine inhibits the reaction [TNF results in increased expression of ICAM1 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of ICAM1 protein]
Glucosamine results in decreased activity of ICAM1 protein
Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of ICAM1 protein]		 CTD PMID:16431966 PMID:16822504 PMID:17238806 PMID:18949387 PMID:19020780 More... NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615 		JBrowse link
G ID1 inhibitor of DNA binding 1 increases expression ISO Glucosamine results in increased expression of ID1 mRNA CTD PMID:17178593 NCBI chr20:31,605,289...31,606,510
Ensembl chr20:31,605,283...31,606,515 		JBrowse link
G ID2 inhibitor of DNA binding 2 increases expression ISO Glucosamine results in increased expression of ID2 mRNA CTD PMID:17178593 NCBI chr 2:8,682,056...8,684,461
Ensembl chr 2:8,678,845...8,684,461 		JBrowse link
G ID3 inhibitor of DNA binding 3 increases expression ISO Glucosamine results in increased expression of ID3 mRNA CTD PMID:17178593 NCBI chr 1:23,557,926...23,559,501
Ensembl chr 1:23,557,926...23,559,501 		JBrowse link
G IDH1 isocitrate dehydrogenase (NADP(+)) 1 increases expression ISO Glucosamine results in increased expression of IDH1 mRNA CTD PMID:17178593 NCBI chr 2:208,236,227...208,255,071
Ensembl chr 2:208,236,229...208,266,074 		JBrowse link
G IFI16 interferon gamma inducible protein 16 increases expression ISO Glucosamine results in increased expression of IFI204 mRNA CTD PMID:17178593 NCBI chr 1:158,999,976...159,055,151
Ensembl chr 1:158,999,968...159,055,155 		JBrowse link
G IFIT1B interferon induced protein with tetratricopeptide repeats 1B increases expression ISO Glucosamine results in increased expression of IFIT1 mRNA CTD PMID:17178593 NCBI chr10:89,378,056...89,385,205
Ensembl chr10:89,378,056...89,385,205 		JBrowse link
G IFIT3 interferon induced protein with tetratricopeptide repeats 3 increases expression ISO Glucosamine results in increased expression of IFIT3 mRNA CTD PMID:17178593 NCBI chr10:89,327,997...89,340,968
Ensembl chr10:89,327,307...89,377,473 		JBrowse link
G IFNG interferon gamma decreases secretion
multiple interactions		 ISO
EXP		 Glucosamine results in decreased secretion of IFNG protein
Glucosamine inhibits the reaction [IFNG promotes the reaction [TNF results in increased expression of ICAM1 protein]]; Glucosamine inhibits the reaction [IFNG results in increased expression of ICAM1 mRNA]; Glucosamine inhibits the reaction [IFNG results in increased expression of ICAM1 protein]; Glucosamine inhibits the reaction [IFNG results in increased localization of STAT1 protein modified form]; Glucosamine inhibits the reaction [IFNG results in increased phosphorylation of and results in increased localization of STAT1 protein]; Glucosamine inhibits the reaction [TNF promotes the reaction [IFNG results in increased expression of ICAM1 protein]]		 CTD PMID:14507305 PMID:16431966 PMID:16822504 PMID:17238806 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740 		JBrowse link
G IGFBP3 insulin like growth factor binding protein 3 multiple interactions
decreases expression		 ISO Glucosamine inhibits the reaction [IL1B results in increased expression of IGFBP3 mRNA]; IL1B inhibits the reaction [Glucosamine results in increased expression of IGFBP3 mRNA]
Glucosamine results in decreased expression of IGFBP3 mRNA		 CTD PMID:17109745 NCBI chr 7:45,912,245...45,921,272
Ensembl chr 7:45,912,245...45,921,874 		JBrowse link
G IGFBP4 insulin like growth factor binding protein 4 decreases expression ISO Glucosamine results in decreased expression of IGFBP4 mRNA CTD PMID:17178593 NCBI chr17:40,443,450...40,457,725
Ensembl chr17:40,443,450...40,457,725 		JBrowse link
G IGFBP5 insulin like growth factor binding protein 5 multiple interactions
increases expression		 ISO Glucosamine inhibits the reaction [IL1B results in increased expression of IGFBP5 mRNA]
Glucosamine results in increased expression of IGFBP5 mRNA		 CTD PMID:17109745 NCBI chr 2:216,672,105...216,695,549
Ensembl chr 2:216,672,105...216,695,549 		JBrowse link
G IKBKB inhibitor of nuclear factor kappa B kinase subunit beta multiple interactions ISO Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased expression of IKBKB protein] CTD PMID:18786831 NCBI chr 8:42,271,302...42,332,460
Ensembl chr 8:42,271,302...42,332,460 		JBrowse link
G IKBKG inhibitor of nuclear factor kappa B kinase regulatory subunit gamma multiple interactions
decreases expression		 ISO Glucosamine inhibits the reaction [IL1B results in increased expression of IKBKG mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of IKBKG mRNA] CTD PMID:17109745 NCBI chr  X:154,541,238...154,565,046
Ensembl chr  X:154,541,199...154,565,046 		JBrowse link
G IL11 interleukin 11 multiple interactions ISO Glucosamine inhibits the reaction [IL1B results in increased expression of IL11 mRNA] CTD PMID:17109745 NCBI chr19:55,364,382...55,370,463
Ensembl chr19:55,364,382...55,370,463 		JBrowse link
G IL13RA1 interleukin 13 receptor subunit alpha 1 multiple interactions
decreases expression		 ISO Glucosamine inhibits the reaction [IL1B results in increased expression of IL13RA1 mRNA]
Glucosamine results in decreased expression of IL13RA1 mRNA		 CTD PMID:17109745 NCBI chr  X:118,727,606...118,805,228
Ensembl chr  X:118,727,133...118,794,535 		JBrowse link
G IL1A interleukin 1 alpha multiple interactions
increases expression		 ISO Glucosamine inhibits the reaction [IL1B results in increased expression of IL1A mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of IL1A mRNA] CTD PMID:17109745 NCBI chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493 		JBrowse link
G IL1B interleukin 1 beta multiple interactions
increases expression
decreases expression		 EXP
ISO		 [Glucosamine co-treated with Chondroitin Sulfates co-treated with IL1B protein] results in decreased expression of NOS2 protein; [Glucosamine co-treated with Chondroitin Sulfates co-treated with IL1B protein] results in decreased expression of PTGES protein; [Glucosamine co-treated with Chondroitin Sulfates co-treated with IL1B protein] results in decreased expression of PTGS2 protein; [Glucosamine co-treated with Chondroitin Sulfates co-treated with IL1B protein] results in increased expression of TIMP3 mRNA; [Glucosamine co-treated with Chondroitin Sulfates] inhibits the reaction [IL1B protein results in increased secretion of Dinoprostone]; [Glucosamine co-treated with Chondroitin Sulfates] inhibits the reaction [IL1B protein results in increased secretion of Nitrites]; Glucosamine analog affects the reaction [IL1B protein results in increased abundance of Nitric Oxide]; Glucosamine analog affects the reaction [IL1B results in decreased expression of ACAN mRNA]; Glucosamine analog affects the reaction [IL1B results in decreased expression of COL2A1 mRNA]; Glucosamine analog affects the reaction [IL1B results in increased phosphorylation of AKT1 protein]; Glucosamine analog inhibits the reaction [IL1B protein results in increased abundance of Dinoprostone]; Glucosamine analog inhibits the reaction [IL1B protein results in increased expression of MMP13]; Glucosamine analog inhibits the reaction [IL1B protein results in increased expression of MMP1]; Glucosamine analog inhibits the reaction [IL1B protein results in increased expression of MMP3]; Glucosamine analog inhibits the reaction [IL1B results in increased expression of and results in increased secretion of MMP1 protein]; Glucosamine analog inhibits the reaction [IL1B results in increased expression of and results in increased secretion of MMP13 protein]; Glucosamine analog inhibits the reaction [IL1B results in increased expression of and results in increased secretion of MMP3 protein]; Glucosamine analog inhibits the reaction [IL1B results in increased expression of CXCL8 mRNA]; Glucosamine analog inhibits the reaction [IL1B results in increased expression of MMP1 mRNA]; Glucosamine analog inhibits the reaction [IL1B results in increased expression of MMP13 mRNA]; Glucosamine analog inhibits the reaction [IL1B results in increased expression of MMP3 mRNA]; Glucosamine analog inhibits the reaction [IL1B results in increased localization of RELA protein]; Glucosamine analog inhibits the reaction [IL1B results in increased phosphorylation of and results in increased degradation of NFKBIA protein]; Glucosamine analog inhibits the reaction [IL1B results in increased secretion of CCL2 protein]; Glucosamine analog inhibits the reaction [IL1B results in increased secretion of CCL5 protein]; Glucosamine analog inhibits the reaction [IL1B results in increased secretion of CXCL8 protein]; Glucosamine analog promotes the reaction [IL1B results in increased phosphorylation of MAPK1 protein]; Glucosamine analog promotes the reaction [IL1B results in increased phosphorylation of MAPK3 protein]; Glucosamine analog promotes the reaction [IL1B results in increased phosphorylation of MAPK8 protein]; Glucosamine inhibits the reaction [[OSM protein co-treated with IL1B protein] results in decreased methylation of IL1B promoter]; Glucosamine inhibits the reaction [[OSM protein co-treated with IL1B protein] results in increased expression of IL1B mRNA]; Glucosamine inhibits the reaction [IL1B promotes the reaction [TNF results in increased expression of ICAM1 protein]]; Glucosamine inhibits the reaction [IL1B protein results in decreased expression of ACAN mRNA]; Glucosamine inhibits the reaction [IL1B protein results in decreased expression of COL2A1 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased activity of JUN protein]; Glucosamine inhibits the reaction [IL1B protein results in increased activity of JUND protein]; Glucosamine inhibits the reaction [IL1B protein results in increased degradation of NFKBIA protein]; Glucosamine inhibits the reaction [IL1B protein results in increased expression of COL1A1 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased expression of MMP1 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased expression of MMP13 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased expression of MMP3 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased expression of PTGS2 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased expression of PTGS2 protein]; Glucosamine inhibits the reaction [IL1B protein results in increased localization of NFKB1 protein]; Glucosamine inhibits the reaction [IL1B protein results in increased localization of RELA protein]; Glucosamine inhibits the reaction [IL1B protein results in increased secretion of Dinoprostone]; Glucosamine inhibits the reaction [IL1B protein results in increased secretion of MMP1 protein]; Glucosamine inhibits the reaction [IL1B protein results in increased secretion of MMP13 protein]; Glucosamine inhibits the reaction [IL1B protein results in increased secretion of MMP3 protein]; Glucosamine inhibits the reaction [IL1B results in decreased expression of HMOX1 mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of HMOX1 protein]; Glucosamine inhibits the reaction [IL1B results in increased abundance of Dinoprostone]; Glucosamine inhibits the reaction [IL1B results in increased abundance of Nitric Oxide]; Glucosamine inhibits the reaction [IL1B results in increased abundance of Nitrites]; Glucosamine inhibits the reaction [IL1B results in increased degradation of NFKB1 protein]; Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL8 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL8 protein]; Glucosamine inhibits the reaction [IL1B results in increased expression of ICAM1 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of ICAM1 protein]; Glucosamine inhibits the reaction [IL1B results in increased expression of MMP3 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of MMP3 protein]; Glucosamine inhibits the reaction [IL1B results in increased expression of NOS2 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of PTGES mRNA]; Glucosamine inhibits the reaction [IL1B results in increased localization of RELA protein]; Glucosamine inhibits the reaction [IL1B results in increased phosphorylation of MAPK1 protein]; Glucosamine inhibits the reaction [IL1B results in increased phosphorylation of MAPK14 protein]; Glucosamine inhibits the reaction [IL1B results in increased phosphorylation of MAPK3 protein]; Glucosamine inhibits the reaction [IL1B results in increased phosphorylation of MAPK8 protein]; Glucosamine inhibits the reaction [IL1B results in increased secretion of CXCL8 protein]; Glucosamine inhibits the reaction [TNF promotes the reaction [IL1B results in increased expression of ICAM1 protein]]; Glucosamine promotes the reaction [IL1B results in increased expression of PPARG]; Glucosamine promotes the reaction [IL1B results in increased phosphorylation of AKT1 protein]
Glucosamine results in increased expression of IL1B mRNA
Glucosamine results in decreased expression of IL1B mRNA
[IL1B protein co-treated with Glucosamine] results in increased expression of IL1R2 mRNA; Glucosamine affects the reaction [IL1B results in decreased expression of ADAM15 mRNA]; Glucosamine affects the reaction [IL1B results in decreased expression of OAT mRNA]; Glucosamine inhibits the reaction [IL1B protein results in decreased activity of B3GAT3 protein]; Glucosamine inhibits the reaction [IL1B protein results in decreased expression of B3GAT3 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased abundance of Dinoprostone]; Glucosamine inhibits the reaction [IL1B protein results in increased abundance of Nitric Oxide]; Glucosamine inhibits the reaction [IL1B protein results in increased expression of MMP3 mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of ACAN mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of COL11A1 mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of COL2A1 mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of COL3A1 mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of FGFR1 mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of HAPLN1 mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of LAMA4 mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of SDC2 mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of SOX4 mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of THBS4 mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of TIMP2 mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of TIMP3 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of ADAM17 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of ADAMTS1 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of ASS1 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of BGN mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of BMP2 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of BMP6 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of BMP7 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CCL2 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CCL20 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CCL22 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CCL3 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CCL5 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CCL7 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of COL8A1 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CSF1 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CSF2 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CSF3 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL1 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL10 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL11 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL2 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL3 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL5 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of DUSP5 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of DUSP7 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of EPAS1 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of FGF9 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of GREM1 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of IGFBP3 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of IGFBP5 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of IKBKG mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of IL11 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of IL13RA1 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of IL1A mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of IL1B mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of IL23R mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of IL6 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of JAK2 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of JUNB mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of MMP10 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of MMP12 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of MMP13 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of MMP3 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of MMP9 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of NFKBIA mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of NFKBIB mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of NGF mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of NOS2 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of PDGFA mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of PLA2G2A mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of PLA2G4A mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of PLA2G5 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of RELB mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of SDC4 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of SLC7A8 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of TIMP1 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of TNFAIP6 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of TNK2 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of VCAN mRNA]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; Glucosamine promotes the reaction [IL1B results in decreased expression of BMP4 mRNA]; Glucosamine promotes the reaction [IL1B results in decreased expression of CXCL12 mRNA]; IL1B affects the reaction [Glucosamine affects the expression of PDGFA mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of ADAM15 mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of BGN mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of COL11A1 mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of CXCL12 mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of DUSP7 mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of EPAS1 mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of IKBKG mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of JUNB mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of TNFAIP6 mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of VCAN mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of ADAM17 mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of IL1A mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of JAK2 mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of LAMA4 mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of MMP9 mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of NFKBIB mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of TIMP3 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of ADAMTS1 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of COL8A1 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of CSF1 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of CXCL1 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of FGF7 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of GREM1 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of NFKBIA mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of PLA2G2A mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of PLA2G5 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of SDC4 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of SLC7A8 mRNA]; IL1B inhibits the reaction [Glucosamine results in increased expression of IGFBP3 mRNA]; IL1B promotes the reaction [Glucosamine results in decreased expression of HAPLN1 mRNA]; IL1B promotes the reaction [Glucosamine results in decreased expression of SDC2 mRNA]; IL1B promotes the reaction [Glucosamine results in decreased expression of THBS4 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of AZIN1 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of CCL2 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of CCL20 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of CCL7 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of CXCL2 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of CXCL3 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of MMP10 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of MMP12 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of MMP13 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of MMP2 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of MMP3 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of NOS2 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of TIMP1 mRNA]
Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased secretion of IL1B protein]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]		 CTD PMID:11229466 PMID:11801247 PMID:12681956 PMID:15144122 PMID:16822504 More... NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL1R2 interleukin 1 receptor type 2 multiple interactions ISO [IL1B protein co-treated with Glucosamine] results in increased expression of IL1R2 mRNA CTD PMID:11801247 NCBI chr 2:101,991,960...102,028,544
Ensembl chr 2:101,991,960...102,028,544 		JBrowse link
G IL2 interleukin 2 decreases secretion ISO Glucosamine results in decreased secretion of IL2 protein CTD PMID:14507305 NCBI chr 4:122,451,470...122,456,725
Ensembl chr 4:122,451,470...122,456,725 		JBrowse link
G IL23R interleukin 23 receptor multiple interactions ISO Glucosamine inhibits the reaction [IL1B results in increased expression of IL23R mRNA] CTD PMID:17109745 NCBI chr 1:67,138,637...67,265,903
Ensembl chr 1:67,138,907...67,259,979 		JBrowse link
G IL33 interleukin 33 decreases expression ISO Glucosamine results in decreased expression of IL33 mRNA CTD PMID:17109745 NCBI chr 9:6,215,149...6,257,983
Ensembl chr 9:6,215,786...6,257,983 		JBrowse link
G IL4 interleukin 4 decreases secretion
decreases expression		 ISO
EXP		 Glucosamine results in decreased secretion of IL4 protein
Glucosamine results in decreased expression of IL4		 CTD PMID:14507305 PMID:21284687 NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678 		JBrowse link
G IL5 interleukin 5 decreases secretion
decreases expression		 ISO
EXP		 Glucosamine results in decreased secretion of IL5 protein
Glucosamine results in decreased expression of IL5		 CTD PMID:14507305 PMID:21284687 NCBI chr 5:132,541,445...132,556,815
Ensembl chr 5:132,541,445...132,556,838 		JBrowse link
G IL6 interleukin 6 multiple interactions
decreases expression		 EXP
ISO		 Glucosamine analog inhibits the reaction [TNF results in increased expression of IL6 mRNA]; Glucosamine inhibits the reaction [[IL6 co-treated with TNF] results in increased expression of ICAM1 protein]; Glucosamine inhibits the reaction [IL6 results in increased expression of ICAM1 protein]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased secretion of IL6 protein]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of IL6 mRNA]
Glucosamine inhibits the reaction [IL1B results in increased expression of IL6 mRNA]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]
Glucosamine analog results in decreased expression of IL6 mRNA; Glucosamine results in decreased expression of IL6 mRNA
Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased secretion of IL6 protein]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]		 CTD PMID:16822504 PMID:17109745 PMID:18786831 PMID:19098112 PMID:20093129 More... NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G INPP5K inositol polyphosphate-5-phosphatase K multiple interactions
increases expression		 EXP NUS1 protein inhibits the reaction [Glucosamine results in increased expression of INPP5K mRNA] CTD PMID:33812996 NCBI chr17:1,494,577...1,516,612
Ensembl chr17:1,494,577...1,516,742 		JBrowse link
G INS insulin multiple interactions EXP 4-phenylbutyric acid inhibits the reaction [Glucosamine inhibits the reaction [INS results in increased uptake of Deoxyglucose]]; Glucosamine inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]; Glucosamine inhibits the reaction [INS results in increased uptake of Deoxyglucose]; NUS1 protein inhibits the reaction [Glucosamine inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]]; PRKAA1 protein promotes the reaction [Glucosamine inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]]; PRKAA1 protein promotes the reaction [NUS1 protein inhibits the reaction [Glucosamine inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]]]; ursodoxicoltaurine inhibits the reaction [Glucosamine inhibits the reaction [INS results in increased uptake of Deoxyglucose]] CTD PMID:20165829 PMID:33812996 NCBI chr11:2,159,779...2,161,209
Ensembl chr11:2,159,779...2,161,221 		JBrowse link
G INS-IGF2 INS-IGF2 readthrough multiple interactions ISO [INS1 protein co-treated with Glucosamine] results in increased expression of OSTN mRNA; Glucosamine inhibits the reaction [INS1 protein results in increased phosphorylation of AKT1 protein]; Glucosamine inhibits the reaction [INS1 protein results in increased uptake of 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose]; INS1 inhibits the reaction [[Streptozocin co-treated with APOE mutant form] results in increased abundance of Glucosamine]; OSTN protein affects the reaction [Glucosamine inhibits the reaction [INS1 protein results in increased phosphorylation of AKT1 protein]]; OSTN protein affects the reaction [Glucosamine inhibits the reaction [INS1 protein results in increased uptake of 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose]]
4-phenylbutyric acid inhibits the reaction [Glucosamine inhibits the reaction [INS1 results in increased uptake of Deoxyglucose]]; [Glucosamine co-treated with INS1 protein] affects the localization of GFPT1 protein; Glucosamine inhibits the reaction [Glucose results in increased secretion of INS1 protein]; Glucosamine inhibits the reaction [INS1 protein results in increased uptake of Deoxyglucose]; Glucosamine inhibits the reaction [INS1 results in increased uptake of Deoxyglucose]; ursodoxicoltaurine inhibits the reaction [Glucosamine inhibits the reaction [INS1 results in increased uptake of Deoxyglucose]]		 CTD PMID:9453242 PMID:11893929 PMID:16380481 PMID:20165829 PMID:30602124 NCBI chr11:2,129,117...2,161,209
Ensembl chr11:2,132,538...2,161,209 		JBrowse link
G IRF1 interferon regulatory factor 1 multiple interactions ISO Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of IRF1 mRNA] CTD PMID:20737476 NCBI chr 5:132,481,609...132,490,773
Ensembl chr 5:132,440,440...132,508,719 		JBrowse link
G ISYNA1 inositol-3-phosphate synthase 1 increases expression ISO Glucosamine results in increased expression of ISYNA1 mRNA CTD PMID:17109745 NCBI chr19:18,434,388...18,438,133
Ensembl chr19:18,434,388...18,438,167 		JBrowse link
G JAK2 Janus kinase 2 multiple interactions
increases expression		 ISO Glucosamine inhibits the reaction [IL1B results in increased expression of JAK2 mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of JAK2 mRNA] CTD PMID:17109745 NCBI chr 9:4,984,390...5,129,948
Ensembl chr 9:4,984,390...5,129,948 		JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP
ISO		 Glucosamine inhibits the reaction [IL1B protein results in increased activity of JUN protein]
Glucosamine analog inhibits the reaction [Buthionine Sulfoximine results in increased expression of JUN mRNA]		 CTD PMID:17925024 PMID:21825963 NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,776,845...58,784,048 		JBrowse link
G JUNB JunB proto-oncogene, AP-1 transcription factor subunit multiple interactions
decreases expression		 ISO Glucosamine inhibits the reaction [IL1B results in increased expression of JUNB mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of JUNB mRNA] CTD PMID:17109745 NCBI chr19:12,791,486...12,793,315
Ensembl chr19:12,791,486...12,793,315 		JBrowse link
G JUND JunD proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP Glucosamine inhibits the reaction [IL1B protein results in increased activity of JUND protein] CTD PMID:17925024 NCBI chr19:18,279,694...18,281,622
Ensembl chr19:18,279,694...18,281,622 		JBrowse link
G KCNJ16 potassium inwardly rectifying channel subfamily J member 16 increases expression ISO Glucosamine results in increased expression of KCNJ16 mRNA CTD PMID:17178593 NCBI chr17:70,075,225...70,135,608
Ensembl chr17:70,053,429...70,135,608 		JBrowse link
G KIF11 kinesin family member 11 decreases expression ISO Glucosamine results in decreased expression of KIF11 mRNA CTD PMID:17109745 NCBI chr10:92,593,130...92,655,395
Ensembl chr10:92,574,105...92,655,395 		JBrowse link
G KIF4A kinesin family member 4A decreases expression ISO Glucosamine results in decreased expression of KIF4A mRNA CTD PMID:17109745 NCBI chr  X:70,290,104...70,420,886
Ensembl chr  X:70,290,104...70,420,886 		JBrowse link
G KLF10 KLF transcription factor 10 increases expression ISO Glucosamine results in increased expression of KLF10 mRNA CTD PMID:17178593 NCBI chr 8:102,648,784...102,655,725
Ensembl chr 8:102,648,784...102,655,725 		JBrowse link
G LAMA4 laminin subunit alpha 4 multiple interactions
increases expression		 ISO Glucosamine inhibits the reaction [IL1B results in decreased expression of LAMA4 mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of LAMA4 mRNA] CTD PMID:17109745 NCBI chr 6:112,107,931...112,254,985
Ensembl chr 6:112,107,931...112,254,939 		JBrowse link
G LAMB1 laminin subunit beta 1 multiple interactions ISO TXNIP promotes the reaction [Glucosamine results in increased expression of LAMB1 mRNA] CTD PMID:17178593 NCBI chr 7:107,923,799...108,003,161
Ensembl chr 7:107,923,799...108,003,213 		JBrowse link
G LAMC1 laminin subunit gamma 1 multiple interactions ISO TXNIP promotes the reaction [Glucosamine results in increased expression of LAMC1 mRNA] CTD PMID:17178593 NCBI chr 1:183,023,420...183,145,592
Ensembl chr 1:183,023,420...183,145,592 		JBrowse link
G LCN2 lipocalin 2 decreases expression ISO Glucosamine results in decreased expression of LCN2 mRNA CTD PMID:17178593 NCBI chr 9:128,149,453...128,153,453
Ensembl chr 9:128,149,071...128,153,453 		JBrowse link
G LEPR leptin receptor affects response to substance
multiple interactions		 ISO LEPR protein affects the susceptibility to Glucosamine
[LEPR protein affects the susceptibility to Glucosamine] which affects the expression of ALB protein		 CTD PMID:33345901 NCBI chr 1:65,420,652...65,641,559
Ensembl chr 1:65,420,652...65,641,559 		JBrowse link
G LPIN1 lipin 1 increases expression ISO Glucosamine results in increased expression of LPIN1 mRNA CTD PMID:17178593 NCBI chr 2:11,677,544...11,827,409
Ensembl chr 2:11,677,595...11,827,409 		JBrowse link
G LY6S lymphocyte antigen 6 family member S increases expression ISO Glucosamine results in increased expression of LY6A mRNA CTD PMID:17178593 NCBI chr 8:143,040,839...143,076,471
Ensembl chr 8:143,040,839...143,048,319 		JBrowse link
G MAFB MAF bZIP transcription factor B increases expression ISO Glucosamine results in increased expression of MAFB mRNA CTD PMID:17109745 NCBI chr20:40,685,848...40,689,236
Ensembl chr20:40,685,848...40,689,236 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 multiple interactions
increases phosphorylation		 EXP Glucosamine analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MAPK1 protein]; Glucosamine analog promotes the reaction [IL1B results in increased phosphorylation of MAPK1 protein]; Glucosamine inhibits the reaction [IL1B results in increased phosphorylation of MAPK1 protein]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]
Glucosamine analog results in increased phosphorylation of MAPK1 protein		 CTD PMID:18080321 PMID:18340449 PMID:19375915 PMID:19626664 PMID:20307528 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680 		JBrowse link
G MAPK14 mitogen-activated protein kinase 14 multiple interactions EXP Glucosamine inhibits the reaction [IL1B results in increased phosphorylation of MAPK14 protein] CTD PMID:19626664 NCBI chr 6:36,027,808...36,124,214
Ensembl chr 6:36,027,782...36,111,236 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 multiple interactions
increases phosphorylation		 EXP Glucosamine analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MAPK3 protein]; Glucosamine analog promotes the reaction [IL1B results in increased phosphorylation of MAPK3 protein]; Glucosamine inhibits the reaction [IL1B results in increased phosphorylation of MAPK3 protein]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK3 protein]
Glucosamine analog results in increased phosphorylation of MAPK3 protein		 CTD PMID:18080321 PMID:18340449 PMID:19375915 PMID:19626664 PMID:20307528 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506 		JBrowse link
G MAPK8 mitogen-activated protein kinase 8 multiple interactions
increases phosphorylation		 EXP Glucosamine analog promotes the reaction [IL1B results in increased phosphorylation of MAPK8 protein]; Glucosamine inhibits the reaction [IL1B results in increased phosphorylation of MAPK8 protein]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein]
Glucosamine analog results in increased phosphorylation of MAPK8 protein		 CTD PMID:18080321 PMID:19626664 PMID:20307528 NCBI chr10:48,306,677...48,439,360
Ensembl chr10:48,306,639...48,439,360 		JBrowse link
G MCL1 MCL1 apoptosis regulator, BCL2 family member decreases expression EXP Glucosamine results in decreased expression of MCL1 mRNA; Glucosamine results in decreased expression of MCL1 protein CTD PMID:22020377 NCBI chr 1:150,574,558...150,579,610
Ensembl chr 1:150,560,895...150,579,738 		JBrowse link
G MEF2A myocyte enhancer factor 2A multiple interactions
decreases expression		 EXP
ISO		 4-phenylbutyric acid inhibits the reaction [Glucosamine results in decreased expression of MEF2A mRNA]; 4-phenylbutyric acid inhibits the reaction [Glucosamine results in decreased expression of MEF2A protein]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of MEF2A mRNA]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of MEF2A protein]; ursodoxicoltaurine inhibits the reaction [Glucosamine results in decreased expression of MEF2A mRNA]; ursodoxicoltaurine inhibits the reaction [Glucosamine results in decreased expression of MEF2A protein]
Glucosamine results in decreased expression of MEF2A mRNA; Glucosamine results in decreased expression of MEF2A protein		 CTD PMID:20165829 NCBI chr15:99,565,417...99,716,488
Ensembl chr15:99,565,417...99,716,488 		JBrowse link
G METTL1 methyltransferase 1, tRNA methylguanosine decreases expression ISO Glucosamine results in decreased expression of METTL1 mRNA CTD PMID:17178593 NCBI chr12:57,768,471...57,772,105
Ensembl chr12:57,768,471...57,772,119 		JBrowse link
G MFAP3L microfibril associated protein 3 like increases expression ISO Glucosamine results in increased expression of MFAP3L mRNA CTD PMID:17178593 NCBI chr 4:169,986,602...170,027,277
Ensembl chr 4:169,986,597...170,033,031 		JBrowse link
G MKI67 marker of proliferation Ki-67 decreases expression ISO Glucosamine results in decreased expression of MKI67 mRNA CTD PMID:17109745 NCBI chr10:128,096,659...128,126,423
Ensembl chr10:128,096,659...128,126,423 		JBrowse link
G MMP1 matrix metallopeptidase 1 multiple interactions EXP Glucosamine analog inhibits the reaction [IL1B protein results in increased expression of MMP1]; Glucosamine analog inhibits the reaction [IL1B results in increased expression of and results in increased secretion of MMP1 protein]; Glucosamine analog inhibits the reaction [IL1B results in increased expression of MMP1 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased expression of MMP1 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased secretion of MMP1 protein] CTD PMID:15144122 PMID:17925024 PMID:18080321 NCBI chr11:102,789,919...102,798,160
Ensembl chr11:102,789,401...102,798,160 		JBrowse link
G MMP10 matrix metallopeptidase 10 increases expression
multiple interactions		 ISO Glucosamine results in increased expression of MMP10 mRNA
Glucosamine inhibits the reaction [IL1B results in increased expression of MMP10 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of MMP10 mRNA]		 CTD PMID:17109745 NCBI chr11:102,770,502...102,780,628
Ensembl chr11:102,770,502...102,780,628 		JBrowse link
G MMP12 matrix metallopeptidase 12 multiple interactions
increases expression		 ISO Glucosamine inhibits the reaction [IL1B results in increased expression of MMP12 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of MMP12 mRNA] CTD PMID:17109745 NCBI chr11:102,862,736...102,874,982
Ensembl chr11:102,862,736...102,874,982 		JBrowse link
G MMP13 matrix metallopeptidase 13 affects expression
multiple interactions
increases expression		 EXP
ISO		 Glucosamine analog affects the expression of MMP13 mRNA
Glucosamine inhibits the reaction [IL1B results in increased expression of MMP13 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of MMP13 mRNA]
Glucosamine analog inhibits the reaction [IL1B protein results in increased expression of MMP13]; Glucosamine analog inhibits the reaction [IL1B results in increased expression of and results in increased secretion of MMP13 protein]; Glucosamine analog inhibits the reaction [IL1B results in increased expression of MMP13 mRNA]; Glucosamine analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP13 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased expression of MMP13 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased secretion of MMP13 protein]		 CTD PMID:15144122 PMID:17109745 PMID:17337215 PMID:17925024 PMID:18080321 More... NCBI chr11:102,942,995...102,955,732
Ensembl chr11:102,942,995...102,955,732 		JBrowse link
G MMP2 matrix metallopeptidase 2 multiple interactions
increases expression		 EXP
ISO		 Glucosamine analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of MMP2 protein]; Glucosamine analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP2 mRNA]; Glucosamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP2 mRNA]; Glucosamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP2 protein]
IL1B promotes the reaction [Glucosamine results in increased expression of MMP2 mRNA]		 CTD PMID:17109745 PMID:17498959 PMID:19375915 NCBI chr16:55,478,830...55,506,691
Ensembl chr16:55,389,700...55,506,691 		JBrowse link
G MMP3 matrix metallopeptidase 3 multiple interactions
increases expression
decreases expression		 EXP
ISO		 [Glucosamine co-treated with Chondroitin Sulfates] results in decreased expression of MMP3 mRNA; [Glucosamine co-treated with Chondroitin Sulfates] results in decreased secretion of MMP3 protein; Glucosamine analog inhibits the reaction [IL1B protein results in increased expression of MMP3]; Glucosamine analog inhibits the reaction [IL1B results in increased expression of and results in increased secretion of MMP3 protein]; Glucosamine analog inhibits the reaction [IL1B results in increased expression of MMP3 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased expression of MMP3 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased secretion of MMP3 protein]; Glucosamine inhibits the reaction [IL1B results in increased expression of MMP3 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of MMP3 protein]; Glucosamine results in decreased expression of and results in decreased activity of MMP3 protein
Glucosamine results in increased expression of MMP3 mRNA
Glucosamine inhibits the reaction [IL1B protein results in increased expression of MMP3 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of MMP3 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of MMP3 mRNA]
Glucosamine analog results in decreased expression of MMP3 mRNA		 CTD PMID:11229466 PMID:12801482 PMID:15144122 PMID:16300972 PMID:17109745 More... NCBI chr11:102,835,801...102,843,609
Ensembl chr11:102,835,801...102,843,609 		JBrowse link
G MMP9 matrix metallopeptidase 9 multiple interactions
increases expression		 EXP
ISO		 Glucosamine analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of MMP9 protein]; Glucosamine analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; Glucosamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; Glucosamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 protein]
Glucosamine results in increased expression of MMP9 mRNA
Glucosamine inhibits the reaction [IL1B results in increased expression of MMP9 mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of MMP9 mRNA]		 CTD PMID:17109745 PMID:17498959 PMID:19375915 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561 		JBrowse link
G MPO myeloperoxidase decreases activity ISO Glucosamine results in decreased activity of MPO protein CTD PMID:19098112 NCBI chr17:58,269,855...58,280,935
Ensembl chr17:58,269,855...58,280,935 		JBrowse link
G MVD mevalonate diphosphate decarboxylase increases expression ISO Glucosamine results in increased expression of MVD mRNA CTD PMID:17178593 NCBI chr16:88,651,940...88,663,091
Ensembl chr16:88,651,935...88,663,161 		JBrowse link
G NDUFA4 NDUFA4 mitochondrial complex associated increases expression ISO Glucosamine results in increased expression of NDUFA4 mRNA CTD PMID:17109745 NCBI chr 7:10,931,943...10,940,153
Ensembl chr 7:10,931,943...10,940,153 		JBrowse link
G NEDD4 NEDD4 E3 ubiquitin protein ligase decreases expression ISO Glucosamine results in decreased expression of NEDD4 mRNA CTD PMID:17109745 NCBI chr15:55,826,917...55,993,612
Ensembl chr15:55,826,922...55,993,660 		JBrowse link
G NFKB1 nuclear factor kappa B subunit 1 multiple interactions
decreases activity		 EXP
ISO		 Glucosamine inhibits the reaction [Hydrogen Peroxide results in increased expression of and results in increased localization of NFKB1 protein]; Glucosamine inhibits the reaction [IL1B protein results in increased localization of NFKB1 protein]; Glucosamine inhibits the reaction [IL1B results in increased degradation of NFKB1 protein]; Glucosamine inhibits the reaction [NFKB1 results in increased degradation of RELA protein]; Glucosamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NFKB1 protein]
Glucosamine results in decreased activity of NFKB1 protein
Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased expression of NFKB1 protein]		 CTD PMID:12681956 PMID:16431966 PMID:16822504 PMID:17498959 PMID:18036590 More... NCBI chr 4:102,501,359...102,617,302
Ensembl chr 4:102,501,330...102,617,302 		JBrowse link
G NFKBIA NFKB inhibitor alpha multiple interactions
decreases phosphorylation
decreases expression		 EXP
ISO		 Glucosamine analog inhibits the reaction [IL1B results in increased phosphorylation of and results in increased degradation of NFKBIA protein]; Glucosamine inhibits the reaction [IL1B protein results in increased degradation of NFKBIA protein]
Glucosamine results in decreased phosphorylation of NFKBIA protein
Glucosamine results in decreased expression of NFKBIA mRNA
Glucosamine inhibits the reaction [IL1B results in increased expression of NFKBIA mRNA]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of NFKBIA protein]; IL1B inhibits the reaction [Glucosamine results in decreased expression of NFKBIA mRNA]
Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased expression of NFKBIA protein modified form]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of NFKBIA protein]		 CTD PMID:12681956 PMID:17109745 PMID:18080321 PMID:18205790 PMID:19098112 NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749 		JBrowse link
G NFKBIB NFKB inhibitor beta multiple interactions
increases expression		 ISO Glucosamine inhibits the reaction [IL1B results in increased expression of NFKBIB mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of NFKBIB mRNA] CTD PMID:17109745 NCBI chr19:38,899,666...38,908,889
Ensembl chr19:38,899,700...38,908,893 		JBrowse link
G NGEF neuronal guanine nucleotide exchange factor increases expression ISO Glucosamine results in increased expression of NGEF mRNA CTD PMID:17178593 NCBI chr 2:232,878,701...233,013,256
Ensembl chr 2:232,878,701...233,013,256 		JBrowse link
G NGF nerve growth factor multiple interactions ISO Glucosamine inhibits the reaction [IL1B results in increased expression of NGF mRNA] CTD PMID:17109745 NCBI chr 1:115,285,917...115,338,249
Ensembl chr 1:115,285,904...115,338,770 		JBrowse link
G NOS2 nitric oxide synthase 2 multiple interactions
increases expression
decreases expression		 EXP
ISO		 [Glucosamine co-treated with Chondroitin Sulfates co-treated with IL1B protein] results in decreased expression of NOS2 protein; Glucosamine inhibits the reaction [IL1B results in increased expression of NOS2 mRNA]
Glucosamine results in increased expression of NOS2 mRNA
Glucosamine inhibits the reaction [IL1B results in increased expression of NOS2 mRNA]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of NOS2 mRNA]
Glucosamine results in decreased expression of NOS2 mRNA
Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]; Glucosamine inhibits the reaction [Lipopolysaccharides promotes the reaction [RELA protein binds to NOS2 promoter]]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]		 CTD PMID:17109745 PMID:17440993 PMID:17605605 PMID:18077487 PMID:18205790 More... NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529 		JBrowse link
G NR1H4 nuclear receptor subfamily 1 group H member 4 affects expression ISO Glucosamine affects the expression of NR1H4 CTD PMID:19373748 NCBI chr12:100,473,866...100,564,414
Ensembl chr12:100,473,708...100,564,414 		JBrowse link
G NSDHL NAD(P) dependent steroid dehydrogenase-like increases expression ISO Glucosamine results in increased expression of NSDHL mRNA CTD PMID:17178593 NCBI chr  X:152,831,063...152,869,729
Ensembl chr  X:152,830,967...152,869,729 		JBrowse link
G NUCB2 nucleobindin 2 decreases expression ISO Glucosamine results in decreased expression of NUCB2 mRNA CTD PMID:17178593 NCBI chr11:17,276,739...17,349,980
Ensembl chr11:17,208,153...17,349,980 		JBrowse link
G NUF2 NUF2 component of NDC80 kinetochore complex decreases expression ISO Glucosamine results in decreased expression of NUF2 mRNA CTD PMID:17109745 NCBI chr 1:163,321,954...163,355,759
Ensembl chr 1:163,266,576...163,355,764 		JBrowse link
G NUS1 NUS1 dehydrodolichyl diphosphate synthase subunit multiple interactions EXP NUS1 protein inhibits the reaction [Glucosamine inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]]; NUS1 protein inhibits the reaction [Glucosamine results in increased expression of ATF4 mRNA]; NUS1 protein inhibits the reaction [Glucosamine results in increased expression of ATF6 mRNA]; NUS1 protein inhibits the reaction [Glucosamine results in increased expression of DDIT3 mRNA]; NUS1 protein inhibits the reaction [Glucosamine results in increased expression of EIF2AK3 protein]; NUS1 protein inhibits the reaction [Glucosamine results in increased expression of ERN1 mRNA]; NUS1 protein inhibits the reaction [Glucosamine results in increased expression of HSPA5 mRNA]; NUS1 protein inhibits the reaction [Glucosamine results in increased expression of HSPA5 protein]; NUS1 protein inhibits the reaction [Glucosamine results in increased expression of INPP5K mRNA]; NUS1 protein inhibits the reaction [Glucosamine results in increased phosphorylation of EIF2S1 protein]; NUS1 protein inhibits the reaction [Glucosamine results in increased splicing of XBP1 mRNA]; PRKAA1 protein promotes the reaction [NUS1 protein inhibits the reaction [Glucosamine inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]]] CTD PMID:33812996 NCBI chr 6:117,675,469...117,710,727
Ensembl chr 6:117,675,469...117,710,727 		JBrowse link
G OASL2P 2'-5' oligoadenylate synthetase like 2, pseudogene increases expression ISO Glucosamine results in increased expression of OASL2 mRNA CTD PMID:17178593 NCBI chr12:121,053,732...121,059,670
Ensembl chr12:121,053,732...121,059,670 		JBrowse link
G OAT ornithine aminotransferase multiple interactions ISO Glucosamine affects the reaction [IL1B results in decreased expression of OAT mRNA] CTD PMID:17109745 NCBI chr10:124,397,303...124,418,923
Ensembl chr10:124,397,303...124,418,976 		JBrowse link
G OGT O-linked N-acetylglucosamine (GlcNAc) transferase decreases expression ISO Glucosamine results in decreased expression of OGT mRNA CTD PMID:17178593 NCBI chr  X:71,533,104...71,575,892
Ensembl chr  X:71,533,087...71,575,892 		JBrowse link
G ORC2 origin recognition complex subunit 2 decreases expression ISO Glucosamine results in decreased expression of ORC2 mRNA CTD PMID:17178593 NCBI chr 2:200,908,977...200,963,660
Ensembl chr 2:200,908,977...200,963,680 		JBrowse link
G OSM oncostatin M multiple interactions EXP Glucosamine inhibits the reaction [[OSM protein co-treated with IL1B protein] results in decreased methylation of IL1B promoter]; Glucosamine inhibits the reaction [[OSM protein co-treated with IL1B protein] results in increased expression of IL1B mRNA] CTD PMID:21219853 NCBI chr22:30,262,829...30,266,851
Ensembl chr22:30,262,829...30,266,851 		JBrowse link
G OSTN osteocrin multiple interactions
increases expression		 ISO 4-methylumbelliferone 8-carbaldehyde inhibits the reaction [Glucosamine results in increased expression of OSTN mRNA]; 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of OSTN mRNA]; [INS1 protein co-treated with Glucosamine] results in increased expression of OSTN mRNA; ATF6 protein affects the reaction [Glucosamine results in increased expression of OSTN mRNA]; EIF2AK3 protein affects the reaction [Glucosamine results in increased expression of OSTN mRNA]; ERN1 protein affects the reaction [Glucosamine results in increased expression of OSTN mRNA]; GSK2656157 inhibits the reaction [Glucosamine results in increased expression of OSTN mRNA]; OSTN protein affects the reaction [Glucosamine inhibits the reaction [INS1 protein results in increased phosphorylation of AKT1 protein]]; OSTN protein affects the reaction [Glucosamine inhibits the reaction [INS1 protein results in increased uptake of 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose]] CTD PMID:30602124 NCBI chr 3:191,199,241...191,265,615
Ensembl chr 3:191,199,241...191,265,615 		JBrowse link
G OXR1 oxidation resistance 1 decreases expression ISO Glucosamine results in decreased expression of OXR1 mRNA CTD PMID:17178593 NCBI chr 8:106,270,178...106,752,694
Ensembl chr 8:106,270,144...106,752,694 		JBrowse link
G PANK1 pantothenate kinase 1 increases expression ISO Glucosamine results in increased expression of PANK1 mRNA CTD PMID:17178593 NCBI chr10:89,579,495...89,645,242
Ensembl chr10:89,579,497...89,645,242 		JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 increases cleavage
multiple interactions		 EXP Glucosamine results in increased cleavage of PARP1 protein
pepstatin inhibits the reaction [Glucosamine results in increased cleavage of PARP1 protein]		 CTD PMID:16850161 NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154 		JBrowse link
G PDGFA platelet derived growth factor subunit A affects expression
multiple interactions		 ISO Glucosamine affects the expression of PDGFA mRNA
Glucosamine inhibits the reaction [IL1B results in increased expression of PDGFA mRNA]; IL1B affects the reaction [Glucosamine affects the expression of PDGFA mRNA]		 CTD PMID:17109745 NCBI chr 7:497,258...520,700
Ensembl chr 7:497,258...520,296 		JBrowse link
G PDIA4 protein disulfide isomerase family A member 4 decreases expression ISO Glucosamine results in decreased expression of PDIA4 mRNA CTD PMID:17178593 NCBI chr 7:149,003,051...149,028,505
Ensembl chr 7:149,003,062...149,028,662 		JBrowse link
G PDIA6 protein disulfide isomerase family A member 6 decreases expression ISO Glucosamine results in decreased expression of PDIA6 mRNA CTD PMID:17178593 NCBI chr 2:10,783,391...10,837,712
Ensembl chr 2:10,783,391...10,837,977 		JBrowse link
G PDK4 pyruvate dehydrogenase kinase 4 increases expression ISO Glucosamine results in increased expression of PDK4 mRNA CTD PMID:17178593 NCBI chr 7:95,583,499...95,596,516
Ensembl chr 7:95,583,499...95,596,516 		JBrowse link
G PFKP phosphofructokinase, platelet increases expression ISO Glucosamine results in increased expression of PFKP mRNA CTD PMID:17178593 NCBI chr10:3,067,548...3,136,805
Ensembl chr10:3,066,333...3,137,718 		JBrowse link
G PIGA phosphatidylinositol glycan anchor biosynthesis class A decreases expression ISO Glucosamine results in decreased expression of PIGA mRNA CTD PMID:17178593 NCBI chr  X:15,319,451...15,335,554
Ensembl chr  X:15,319,452...15,335,554 		JBrowse link
G PLA2G2A phospholipase A2 group IIA multiple interactions
decreases expression		 ISO Glucosamine inhibits the reaction [IL1B results in increased expression of PLA2G2A mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of PLA2G2A mRNA] CTD PMID:17109745 NCBI chr 1:19,975,431...19,980,434
Ensembl chr 1:19,975,431...19,980,416 		JBrowse link
G PLA2G4A phospholipase A2 group IVA affects expression
multiple interactions		 ISO Glucosamine affects the expression of PLA2G4A mRNA
Glucosamine inhibits the reaction [IL1B results in increased expression of PLA2G4A mRNA]		 CTD PMID:17109745 NCBI chr 1:186,828,949...186,988,981
Ensembl chr 1:186,828,949...186,988,981 		JBrowse link
G PLA2G5 phospholipase A2 group V multiple interactions
decreases expression		 ISO Glucosamine inhibits the reaction [IL1B results in increased expression of PLA2G5 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of PLA2G5 mRNA] CTD PMID:17109745 NCBI chr 1:20,028,408...20,091,911
Ensembl chr 1:20,028,179...20,091,911 		JBrowse link
G PLAT plasminogen activator, tissue type increases expression ISO Glucosamine results in increased expression of PLAT mRNA CTD PMID:17178593 NCBI chr 8:42,174,718...42,207,565
Ensembl chr 8:42,174,718...42,207,709 		JBrowse link
G PLK1 polo like kinase 1 increases expression
decreases expression		 ISO Glucosamine results in increased expression of PLK1 mRNA
Glucosamine results in decreased expression of PLK1 mRNA		 CTD PMID:17109745 PMID:17178593 NCBI chr16:23,678,889...23,690,367
Ensembl chr16:23,677,656...23,690,367 		JBrowse link
G PLPP3 phospholipid phosphatase 3 decreases expression ISO Glucosamine results in decreased expression of PLPP3 mRNA CTD PMID:17109745 NCBI chr 1:56,494,761...56,579,563
Ensembl chr 1:56,494,761...56,645,301 		JBrowse link
G PPARG peroxisome proliferator activated receptor gamma multiple interactions
increases expression		 EXP
ISO		 Glucosamine promotes the reaction [IL1B results in increased expression of PPARG]
Glucosamine results in increased expression of PPARG mRNA		 CTD PMID:15694357 PMID:22089456 NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356 		JBrowse link
G PPARGC1A PPARG coactivator 1 alpha multiple interactions
decreases expression		 EXP
ISO		 4-phenylbutyric acid inhibits the reaction [Glucosamine results in decreased expression of PPARGC1A mRNA]; 4-phenylbutyric acid inhibits the reaction [Glucosamine results in decreased expression of PPARGC1A protein]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of PPARGC1A mRNA]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of PPARGC1A protein]; ursodoxicoltaurine inhibits the reaction [Glucosamine results in decreased expression of PPARGC1A mRNA]; ursodoxicoltaurine inhibits the reaction [Glucosamine results in decreased expression of PPARGC1A protein]
Glucosamine results in decreased expression of PPARGC1A mRNA; Glucosamine results in decreased expression of PPARGC1A protein		 CTD PMID:20165829 NCBI chr 4:23,792,021...24,472,905
Ensembl chr 4:23,755,041...23,904,089 		JBrowse link
G PPM1A protein phosphatase, Mg2+/Mn2+ dependent 1A decreases expression ISO Glucosamine results in decreased expression of PPM1A mRNA CTD PMID:17178593 NCBI chr14:60,245,750...60,299,087
Ensembl chr14:60,245,752...60,299,087 		JBrowse link
G PPP1R15A protein phosphatase 1 regulatory subunit 15A decreases expression ISO Glucosamine results in decreased expression of PPP1R15A mRNA CTD PMID:17178593 NCBI chr19:48,872,421...48,876,058
Ensembl chr19:48,872,212...48,876,059 		JBrowse link
G PRC1 protein regulator of cytokinesis 1 decreases expression ISO Glucosamine results in decreased expression of PRC1 mRNA CTD PMID:17109745 NCBI chr15:90,966,040...90,994,535
Ensembl chr15:90,966,040...90,995,629 		JBrowse link
G PRKAA1 protein kinase AMP-activated catalytic subunit alpha 1 multiple interactions EXP PRKAA1 protein promotes the reaction [Glucosamine inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]]; PRKAA1 protein promotes the reaction [NUS1 protein inhibits the reaction [Glucosamine inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]]] CTD PMID:33812996 NCBI chr 5:40,759,389...40,798,374
Ensembl chr 5:40,759,389...40,798,374 		JBrowse link
G PSME3 proteasome activator subunit 3 decreases expression EXP Glucosamine results in decreased expression of PSME3 CTD PMID:21697645 NCBI chr17:42,833,397...42,843,760
Ensembl chr17:42,824,385...42,843,760 		JBrowse link
G PTGES prostaglandin E synthase multiple interactions EXP [Glucosamine co-treated with Chondroitin Sulfates co-treated with IL1B protein] results in decreased expression of PTGES protein; Glucosamine inhibits the reaction [IL1B results in increased expression of PTGES mRNA] CTD PMID:17605605 PMID:22089456 NCBI chr 9:129,738,349...129,753,042
Ensembl chr 9:129,738,331...129,753,042 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 increases expression
decreases expression
multiple interactions
decreases glycosylation		 EXP
ISO		 Glucosamine analog results in increased expression of PTGS2 protein alternative form
Glucosamine results in decreased expression of PTGS2 mRNA
Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]
Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]; Glucosamine inhibits the reaction [[Lipopolysaccharides results in increased expression of PTGS2 protein] which results in increased secretion of Dinoprostone]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]
Glucosamine results in decreased glycosylation of PTGS2 protein
[Glucosamine co-treated with Chondroitin Sulfates co-treated with IL1B protein] results in decreased expression of PTGS2 protein; Glucosamine inhibits the reaction [IL1B protein results in increased expression of PTGS2 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased expression of PTGS2 protein]		 CTD PMID:12681956 PMID:17440993 PMID:17605605 PMID:18205790 PMID:19656660 More... NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922 		JBrowse link
G PTTG1 PTTG1 regulator of sister chromatid separation, securin decreases expression ISO Glucosamine results in decreased expression of PTTG1 mRNA CTD PMID:17109745 NCBI chr 5:160,421,855...160,428,744
Ensembl chr 5:160,421,855...160,428,739 		JBrowse link
G RAB32 RAB32, member RAS oncogene family increases expression ISO Glucosamine results in increased expression of RAB32 mRNA CTD PMID:17178593 NCBI chr 6:146,543,833...146,554,953
Ensembl chr 6:146,543,833...146,554,953 		JBrowse link
G RACGAP1 Rac GTPase activating protein 1 decreases expression ISO Glucosamine results in decreased expression of RACGAP1 mRNA CTD PMID:17109745 NCBI chr12:49,989,162...50,033,440
Ensembl chr12:49,976,923...50,033,136 		JBrowse link
G RBM39 RNA binding motif protein 39 decreases expression ISO Glucosamine results in decreased expression of RBM39 mRNA CTD PMID:17178593 NCBI chr20:35,701,347...35,742,260
Ensembl chr20:35,701,347...35,742,312 		JBrowse link
G RECQL4 RecQ like helicase 4 increases expression ISO Glucosamine results in increased expression of RECQL4 mRNA CTD PMID:17178593 NCBI chr 8:144,511,288...144,517,833
Ensembl chr 8:144,511,288...144,517,845 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit multiple interactions
decreases activity
increases localization		 EXP
ISO		 Alloxan inhibits the reaction [Glucosamine inhibits the reaction [TNF results in increased phosphorylation of RELA protein]]; Glucosamine analog inhibits the reaction [IL1B results in increased localization of RELA protein]; Glucosamine analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of RELA protein]; Glucosamine inhibits the reaction [Hydrogen Peroxide results in increased expression of and results in increased localization of RELA protein]; Glucosamine inhibits the reaction [IL1B protein results in increased localization of RELA protein]; Glucosamine inhibits the reaction [IL1B results in increased localization of RELA protein]; Glucosamine inhibits the reaction [NFKB1 results in increased degradation of RELA protein]; Glucosamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of RELA protein]; Glucosamine inhibits the reaction [TNF results in increased localization of RELA protein]; Glucosamine inhibits the reaction [TNF results in increased phosphorylation of RELA protein]
Glucosamine results in decreased activity of RELA protein
Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased expression of RELA protein]; Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased localization of RELA protein]; Glucosamine inhibits the reaction [Lipopolysaccharides promotes the reaction [RELA protein binds to NOS2 promoter]]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of RELA mRNA]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased localization of RELA protein]
Glucosamine results in increased localization of RELA protein		 CTD PMID:12681956 PMID:16431966 PMID:16822504 PMID:17238806 PMID:17498959 More... NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090 		JBrowse link
G RELB RELB proto-oncogene, NF-kB subunit multiple interactions ISO Glucosamine inhibits the reaction [IL1B results in increased expression of RELB mRNA] CTD PMID:17109745 NCBI chr19:45,001,464...45,038,192
Ensembl chr19:45,001,461...45,038,192 		JBrowse link
G RHOB ras homolog family member B increases expression ISO Glucosamine results in increased expression of RHOB mRNA CTD PMID:17178593 NCBI chr 2:20,447,074...20,449,440
Ensembl chr 2:20,447,074...20,449,440 		JBrowse link
G RHOC ras homolog family member C decreases expression EXP Glucosamine analog results in decreased expression of RHOC mRNA CTD PMID:16142878 NCBI chr 1:112,701,131...112,707,408
Ensembl chr 1:112,701,127...112,707,434 		JBrowse link
G RND1 Rho family GTPase 1 multiple interactions
decreases expression		 EXP
ISO		 Glucosamine analog inhibits the reaction [TNF results in increased expression of RND1 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of RND1 mRNA]
Glucosamine results in decreased expression of RND1 mRNA		 CTD PMID:17178593 PMID:18173918 NCBI chr12:48,857,145...48,865,870
Ensembl chr12:48,857,145...48,865,870 		JBrowse link
G RPS6 ribosomal protein S6 decreases phosphorylation EXP Glucosamine results in decreased phosphorylation of RPS6 protein CTD PMID:19254699 NCBI chr 9:19,375,715...19,380,236
Ensembl chr 9:19,375,715...19,380,236 		JBrowse link
G RPS6KB1 ribosomal protein S6 kinase B1 decreases phosphorylation EXP Glucosamine results in decreased phosphorylation of RPS6KB1 protein CTD PMID:19254699 NCBI chr17:59,893,121...59,950,574
Ensembl chr17:59,893,046...59,950,574 		JBrowse link
G RUNX2 RUNX family transcription factor 2 increases phosphorylation
increases expression
multiple interactions		 EXP Glucosamine analog results in increased phosphorylation of RUNX2 protein
Glucosamine analog results in increased expression of RUNX2 mRNA
4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [Glucosamine analog results in increased phosphorylation of RUNX2 protein]		 CTD PMID:20458730 NCBI chr 6:45,328,330...45,551,082
Ensembl chr 6:45,328,157...45,664,349 		JBrowse link
G SCD stearoyl-CoA desaturase increases expression ISO Glucosamine results in increased expression of SCD2 mRNA CTD PMID:17178593 NCBI chr10:100,347,233...100,364,826
Ensembl chr10:100,347,233...100,364,826 		JBrowse link
G SDC2 syndecan 2 multiple interactions
decreases expression		 ISO Glucosamine inhibits the reaction [IL1B results in decreased expression of SDC2 mRNA]; IL1B promotes the reaction [Glucosamine results in decreased expression of SDC2 mRNA] CTD PMID:17109745 NCBI chr 8:96,493,813...96,611,790
Ensembl chr 8:96,493,813...96,611,790 		JBrowse link
G SDC4 syndecan 4 multiple interactions
decreases expression		 ISO Glucosamine inhibits the reaction [IL1B results in increased expression of SDC4 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of SDC4 mRNA] CTD PMID:17109745 NCBI chr20:45,325,288...45,348,424
Ensembl chr20:45,325,288...45,348,424 		JBrowse link
G SELENBP1 selenium binding protein 1 decreases expression ISO Glucosamine results in decreased expression of SELENBP1 mRNA CTD PMID:17109745 NCBI chr 1:151,364,304...151,372,705
Ensembl chr 1:151,364,304...151,372,707 		JBrowse link
G SERPINB2 serpin family B member 2 increases expression ISO Glucosamine results in increased expression of SERPINB2 mRNA CTD PMID:17109745 NCBI chr18:63,887,705...63,903,888
Ensembl chr18:63,871,692...63,903,888 		JBrowse link
G SERPINH1 serpin family H member 1 increases expression EXP Glucosamine results in increased expression of SERPINH1 protein CTD PMID:16380481 NCBI chr11:75,562,253...75,572,783
Ensembl chr11:75,562,056...75,572,783 		JBrowse link
G SFRP2 secreted frizzled related protein 2 decreases expression ISO Glucosamine results in decreased expression of SFRP2 mRNA CTD PMID:17109745 NCBI chr 4:153,780,591...153,789,083
Ensembl chr 4:153,780,591...153,789,083 		JBrowse link
G SGK1 serum/glucocorticoid regulated kinase 1 decreases expression ISO Glucosamine results in decreased expression of SGK1 mRNA CTD PMID:17178593 NCBI chr 6:134,169,256...134,318,112
Ensembl chr 6:134,169,248...134,318,112 		JBrowse link
G SHCBP1 SHC binding and spindle associated 1 decreases expression ISO Glucosamine results in decreased expression of SHCBP1 mRNA CTD PMID:17109745 NCBI chr16:46,578,591...46,621,379
Ensembl chr16:46,578,591...46,621,379 		JBrowse link
G SLC17A1 solute carrier family 17 member 1 increases expression ISO Glucosamine results in increased expression of SLC17A1 mRNA CTD PMID:17178593 NCBI chr 6:25,723,743...25,832,052
Ensembl chr 6:25,782,915...25,832,052 		JBrowse link
G SLC23A2 solute carrier family 23 member 2 increases expression ISO Glucosamine results in increased expression of SLC23A2 mRNA CTD PMID:17109745 NCBI chr20:4,852,358...5,010,313
Ensembl chr20:4,852,356...5,010,293 		JBrowse link
G SLC2A2 solute carrier family 2 member 2 decreases expression ISO Glucosamine results in decreased expression of SLC2A2 mRNA CTD PMID:11893929 NCBI chr 3:170,996,347...171,026,720
Ensembl chr 3:170,996,347...171,026,743 		JBrowse link
G SLC2A4 solute carrier family 2 member 4 multiple interactions
decreases expression
increases uptake		 EXP
ISO		 4-phenylbutyric acid inhibits the reaction [Glucosamine results in decreased expression of SLC2A4 mRNA]; 4-phenylbutyric acid inhibits the reaction [Glucosamine results in decreased expression of SLC2A4 protein]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of SLC2A4 mRNA]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of SLC2A4 protein]; ursodoxicoltaurine inhibits the reaction [Glucosamine results in decreased expression of SLC2A4 mRNA]; ursodoxicoltaurine inhibits the reaction [Glucosamine results in decreased expression of SLC2A4 protein]
Glucosamine results in decreased expression of SLC2A4 mRNA; Glucosamine results in decreased expression of SLC2A4 protein
SLC2A4 protein results in increased uptake of Glucosamine
Glucosamine inhibits the reaction [SLC2A4 protein results in increased uptake of Glucose]; Glucose inhibits the reaction [SLC2A4 protein results in increased uptake of Glucosamine]		 CTD PMID:19373748 PMID:20165829 NCBI chr17:7,281,718...7,288,257
Ensembl chr17:7,281,718...7,288,257 		JBrowse link
G SLC2A6 solute carrier family 2 member 6 decreases expression ISO Glucosamine results in decreased expression of SLC2A6 mRNA CTD PMID:17178593 NCBI chr 9:133,471,094...133,479,099
Ensembl chr 9:133,471,094...133,479,127 		JBrowse link
G SLC37A4 solute carrier family 37 member 4 increases expression ISO Glucosamine results in increased expression of SLC37A4 mRNA CTD PMID:17178593 NCBI chr11:119,024,112...119,030,877
Ensembl chr11:119,023,751...119,030,906 		JBrowse link
G SLC4A4 solute carrier family 4 member 4 decreases expression ISO Glucosamine results in decreased expression of SLC4A4 mRNA CTD PMID:17109745 NCBI chr 4:71,062,660...71,572,083
Ensembl chr 4:71,062,667...71,572,087 		JBrowse link
G SLC7A8 solute carrier family 7 member 8 increases expression
multiple interactions		 ISO Glucosamine results in increased expression of SLC7A8 mRNA
Glucosamine inhibits the reaction [IL1B results in increased expression of SLC7A8 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of SLC7A8 mRNA]		 CTD PMID:17109745 NCBI chr14:23,125,295...23,183,660
Ensembl chr14:23,125,295...23,183,674 		JBrowse link
G SMAD2 SMAD family member 2 multiple interactions
increases phosphorylation		 EXP 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [Glucosamine analog results in increased phosphorylation of SMAD2 protein] CTD PMID:20458730 NCBI chr18:47,808,957...47,930,872
Ensembl chr18:47,808,957...47,931,146 		JBrowse link
G SMPD3 sphingomyelin phosphodiesterase 3 decreases expression ISO Glucosamine results in decreased expression of SMPD3 mRNA CTD PMID:17109745 NCBI chr16:68,358,327...68,448,508
Ensembl chr16:68,358,327...68,448,508 		JBrowse link
G SOX4 SRY-box transcription factor 4 multiple interactions
decreases expression		 ISO Glucosamine inhibits the reaction [IL1B results in decreased expression of SOX4 mRNA]
Glucosamine results in decreased expression of SOX4 mRNA		 CTD PMID:17109745 NCBI chr 6:21,593,751...21,598,619
Ensembl chr 6:21,593,751...21,598,619 		JBrowse link
G SRSF3 serine and arginine rich splicing factor 3 decreases expression ISO Glucosamine results in decreased expression of SRSF3 mRNA CTD PMID:17178593 NCBI chr 6:36,594,362...36,605,600
Ensembl chr 6:36,594,353...36,605,600 		JBrowse link
G ST6GAL1 ST6 beta-galactoside alpha-2,6-sialyltransferase 1 increases expression ISO Glucosamine results in increased expression of ST6GAL1 mRNA CTD PMID:17178593 NCBI chr 3:186,930,526...187,078,553
Ensembl chr 3:186,930,325...187,078,553 		JBrowse link
G STAT1 signal transducer and activator of transcription 1 multiple interactions EXP Glucosamine inhibits the reaction [IFNG results in increased localization of STAT1 protein modified form]; Glucosamine inhibits the reaction [IFNG results in increased phosphorylation of and results in increased localization of STAT1 protein] CTD PMID:16431966 PMID:17238806 NCBI chr 2:190,969,149...191,014,171
Ensembl chr 2:190,908,460...191,020,960 		JBrowse link
G TACC3 transforming acidic coiled-coil containing protein 3 decreases expression ISO Glucosamine results in decreased expression of TACC3 mRNA CTD PMID:17109745 NCBI chr 4:1,721,521...1,745,171
Ensembl chr 4:1,712,858...1,745,171 		JBrowse link
G TGFA transforming growth factor alpha multiple interactions ISO [Glucose co-treated with Glucosamine] results in increased expression of TGFA protein; Glucosamine promotes the reaction [Glucose results in increased expression of TGFA mRNA] CTD PMID:1518840 NCBI chr 2:70,447,284...70,553,826
Ensembl chr 2:70,447,284...70,554,193 		JBrowse link
G TGFB1 transforming growth factor beta 1 increases expression ISO Glucosamine analog results in increased expression of TGFB1 mRNA CTD PMID:21466783 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922 		JBrowse link
G TGFBR1 transforming growth factor beta receptor 1 multiple interactions
increases expression		 EXP 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [Glucosamine analog results in increased expression of TGFBR1 protein] CTD PMID:20458730 NCBI chr 9:99,103,647...99,154,192
Ensembl chr 9:99,104,038...99,154,192 		JBrowse link
G THBS4 thrombospondin 4 multiple interactions
decreases expression		 ISO Glucosamine inhibits the reaction [IL1B results in decreased expression of THBS4 mRNA]; IL1B promotes the reaction [Glucosamine results in decreased expression of THBS4 mRNA] CTD PMID:17109745 NCBI chr 5:79,991,332...80,083,287
Ensembl chr 5:79,991,311...80,083,287 		JBrowse link
G TIMP1 TIMP metallopeptidase inhibitor 1 multiple interactions
increases expression		 ISO Glucosamine inhibits the reaction [IL1B results in increased expression of TIMP1 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of TIMP1 mRNA] CTD PMID:17109745 NCBI chr  X:47,582,436...47,586,789
Ensembl chr  X:47,582,408...47,586,789 		JBrowse link
G TIMP2 TIMP metallopeptidase inhibitor 2 affects expression
multiple interactions		 ISO Glucosamine affects the expression of TIMP2 mRNA
Glucosamine inhibits the reaction [IL1B results in decreased expression of TIMP2 mRNA]		 CTD PMID:17109745 NCBI chr17:78,852,977...78,925,387
Ensembl chr17:78,852,977...78,925,387 		JBrowse link
G TIMP3 TIMP metallopeptidase inhibitor 3 multiple interactions
increases expression		 EXP
ISO		 [Glucosamine co-treated with Chondroitin Sulfates co-treated with IL1B protein] results in increased expression of TIMP3 mRNA
Glucosamine results in increased expression of TIMP3 mRNA
Glucosamine inhibits the reaction [IL1B results in decreased expression of TIMP3 mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of TIMP3 mRNA]		 CTD PMID:17109745 PMID:17605605 NCBI chr22:32,801,705...32,863,041
Ensembl chr22:32,801,705...32,863,041 		JBrowse link
G TINAG tubulointerstitial nephritis antigen increases expression ISO Glucosamine results in increased expression of TINAG mRNA CTD PMID:17178593 NCBI chr 6:54,307,862...54,390,142
Ensembl chr 6:54,307,859...54,390,142 		JBrowse link
G TK1 thymidine kinase 1 decreases expression ISO Glucosamine results in decreased expression of TK1 mRNA CTD PMID:17109745 NCBI chr17:78,174,079...78,187,204
Ensembl chr17:78,174,091...78,187,233 		JBrowse link
G TLR1 toll like receptor 1 increases expression ISO Glucosamine results in increased expression of TLR1 mRNA CTD PMID:17178593 NCBI chr 4:38,787,569...38,805,644
Ensembl chr 4:38,790,677...38,856,817 		JBrowse link
G TNF tumor necrosis factor decreases secretion
multiple interactions
decreases expression		 ISO
EXP		 Glucosamine results in decreased secretion of TNF protein
Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]
Glucosamine analog results in decreased expression of TNF mRNA; Glucosamine results in decreased expression of TNF mRNA
Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased secretion of TNF protein]; Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]
[Glucosamine co-treated with Chondroitin Sulfates] results in decreased expression of TNF; Alloxan inhibits the reaction [Glucosamine inhibits the reaction [TNF results in increased phosphorylation of RELA protein]]; Glucosamine analog inhibits the reaction [TNF results in increased expression of CUL2 mRNA]; Glucosamine analog inhibits the reaction [TNF results in increased expression of CXCL8 mRNA]; Glucosamine analog inhibits the reaction [TNF results in increased expression of GSPT1 mRNA]; Glucosamine analog inhibits the reaction [TNF results in increased expression of IL6 mRNA]; Glucosamine analog inhibits the reaction [TNF results in increased expression of RND1 mRNA]; Glucosamine analog inhibits the reaction [TNF results in increased expression of TNFRSF1A mRNA]; Glucosamine analog inhibits the reaction [TNF results in increased expression of TNFRSF1B mRNA]; Glucosamine analog inhibits the reaction [TNF results in increased expression of TRAF6 mRNA]; Glucosamine inhibits the reaction [[IL6 co-treated with TNF] results in increased expression of ICAM1 protein]; Glucosamine inhibits the reaction [IFNG promotes the reaction [TNF results in increased expression of ICAM1 protein]]; Glucosamine inhibits the reaction [IL1B promotes the reaction [TNF results in increased expression of ICAM1 protein]]; Glucosamine inhibits the reaction [TNF promotes the reaction [IFNG results in increased expression of ICAM1 protein]]; Glucosamine inhibits the reaction [TNF promotes the reaction [IL1B results in increased expression of ICAM1 protein]]; Glucosamine inhibits the reaction [TNF results in increased expression of CCL2 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of CCL2 protein]; Glucosamine inhibits the reaction [TNF results in increased expression of CUL2 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of CXCL8 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of GSPT1 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of ICAM1 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of ICAM1 protein]; Glucosamine inhibits the reaction [TNF results in increased expression of IL6 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of RND1 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of TNFRSF1A mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of TNFRSF1B mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of TRAF6 mRNA]; Glucosamine inhibits the reaction [TNF results in increased localization of RELA protein]; Glucosamine inhibits the reaction [TNF results in increased phosphorylation of RELA protein]		 CTD PMID:14507305 PMID:16431966 PMID:16445576 PMID:16822504 PMID:17238806 More... NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TNFAIP6 TNF alpha induced protein 6 multiple interactions
decreases expression		 ISO Glucosamine inhibits the reaction [IL1B results in increased expression of TNFAIP6 mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of TNFAIP6 mRNA] CTD PMID:17109745 NCBI chr 2:151,357,592...151,381,340
Ensembl chr 2:151,357,592...151,380,046 		JBrowse link
G TNFRSF11B TNF receptor superfamily member 11b multiple interactions EXP [Chondroitin Sulfates co-treated with Glucosamine co-treated with Cholecalciferol] results in increased expression of TNFRSF11B mRNA; [Chondroitin Sulfates co-treated with Glucosamine co-treated with Cholecalciferol] results in increased expression of TNFRSF11B protein; [Chondroitin Sulfates co-treated with Glucosamine] results in increased expression of TNFRSF11B mRNA; [Chondroitin Sulfates co-treated with Glucosamine] results in increased expression of TNFRSF11B protein CTD PMID:17996099 NCBI chr 8:118,923,557...118,951,885
Ensembl chr 8:118,923,557...118,951,885 		JBrowse link
G TNFRSF1A TNF receptor superfamily member 1A multiple interactions EXP Glucosamine analog inhibits the reaction [TNF results in increased expression of TNFRSF1A mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of TNFRSF1A mRNA] CTD PMID:18173918 NCBI chr12:6,328,771...6,342,076
Ensembl chr12:6,328,757...6,342,114 		JBrowse link
G TNFRSF1B TNF receptor superfamily member 1B multiple interactions EXP Glucosamine analog inhibits the reaction [TNF results in increased expression of TNFRSF1B mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of TNFRSF1B mRNA] CTD PMID:18173918 NCBI chr 1:12,166,991...12,209,220
Ensembl chr 1:12,166,991...12,209,228 		JBrowse link
G TNFSF11 TNF superfamily member 11 multiple interactions
increases expression		 EXP [Chondroitin Sulfates co-treated with Glucosamine] inhibits the reaction [Cholecalciferol results in increased expression of TNFSF11 mRNA]; Chondroitin Sulfates inhibits the reaction [Glucosamine results in increased expression of TNFSF11 mRNA] CTD PMID:17996099 NCBI chr13:42,562,736...42,608,013
Ensembl chr13:42,562,736...42,608,013 		JBrowse link
G TNK2 tyrosine kinase non receptor 2 multiple interactions ISO Glucosamine inhibits the reaction [IL1B results in increased expression of TNK2 mRNA] CTD PMID:17109745 NCBI chr 3:195,863,364...195,908,551
Ensembl chr 3:195,863,364...195,911,945 		JBrowse link
G TOP2A DNA topoisomerase II alpha decreases expression ISO Glucosamine results in decreased expression of TOP2A mRNA CTD PMID:17109745 NCBI chr17:40,388,525...40,417,896
Ensembl chr17:40,388,525...40,417,896 		JBrowse link
G TRAF6 TNF receptor associated factor 6 multiple interactions EXP Glucosamine analog inhibits the reaction [TNF results in increased expression of TRAF6 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of TRAF6 mRNA] CTD PMID:18173918 NCBI chr11:36,483,769...36,510,272
Ensembl chr11:36,483,769...36,510,272 		JBrowse link
G TRPV4 transient receptor potential cation channel subfamily V member 4 increases expression ISO Glucosamine results in increased expression of TRPV4 mRNA CTD PMID:17178593 NCBI chr12:109,783,087...109,833,398
Ensembl chr12:109,783,087...109,833,406 		JBrowse link
G TXN thioredoxin decreases expression ISO Glucosamine results in decreased expression of TXN1 protein CTD PMID:17178593 NCBI chr 9:110,243,810...110,256,507
Ensembl chr 9:110,243,810...110,256,507 		JBrowse link
G TXNIP thioredoxin interacting protein increases expression
multiple interactions		 ISO Glucosamine results in increased expression of TXNIP protein
Glucosamine results in increased expression of TXNIP mRNA; Glucosamine results in increased expression of TXNIP protein
Glucosamine promotes the reaction [TXNIP results in increased abundance of Reactive Oxygen Species]; TXNIP promotes the reaction [Glucosamine results in increased expression of LAMB1 mRNA]; TXNIP promotes the reaction [Glucosamine results in increased expression of LAMC1 mRNA]		 CTD PMID:17178593 NCBI chr 1:145,992,435...145,996,579
Ensembl chr 1:145,992,435...145,996,579 		JBrowse link
G UCP2 uncoupling protein 2 decreases expression ISO Glucosamine results in decreased expression of UCP2 mRNA CTD PMID:11893929 NCBI chr11:73,974,672...73,983,202
Ensembl chr11:73,974,672...73,982,843 		JBrowse link
G UQCRH ubiquinol-cytochrome c reductase hinge protein increases expression ISO Glucosamine results in increased expression of UQCRH mRNA CTD PMID:17178593 NCBI chr 1:46,303,698...46,316,776
Ensembl chr 1:46,303,698...46,316,776 		JBrowse link
G VAMP1 vesicle associated membrane protein 1 increases expression ISO Glucosamine results in increased expression of VAMP1 mRNA CTD PMID:17109745 NCBI chr12:6,462,237...6,470,677
Ensembl chr12:6,462,237...6,470,677 		JBrowse link
G VCAN versican multiple interactions
decreases expression		 ISO Glucosamine inhibits the reaction [IL1B results in increased expression of VCAN mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of VCAN mRNA] CTD PMID:17109745 NCBI chr 5:83,471,744...83,582,302
Ensembl chr 5:83,471,618...83,582,303 		JBrowse link
G VEGFA vascular endothelial growth factor A multiple interactions
increases expression
decreases expression		 EXP
ISO		 Glucosamine inhibits the reaction [Oxygen deficiency results in increased expression of VEGFA protein]
Glucosamine results in increased expression of VEGFA protein
Glucosamine results in decreased expression of VEGFA protein		 CTD PMID:16324875 PMID:19254699 NCBI chr 6:43,770,211...43,786,487
Ensembl chr 6:43,770,184...43,786,487 		JBrowse link
G VEGFD vascular endothelial growth factor D increases expression
decreases expression		 ISO Glucosamine results in increased expression of VEGFD mRNA
Glucosamine results in decreased expression of VEGFD mRNA		 CTD PMID:17109745 PMID:17178593 NCBI chr  X:15,345,596...15,384,413
Ensembl chr  X:15,345,596...15,384,413 		JBrowse link
G VNN1 vanin 1 increases expression ISO Glucosamine results in increased expression of VNN1 mRNA CTD PMID:17178593 NCBI chr 6:132,680,849...132,714,055
Ensembl chr 6:132,680,849...132,714,055 		JBrowse link
G XBP1 X-box binding protein 1 multiple interactions
increases splicing
increases expression
decreases splicing		 EXP
ISO		 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of XBP1 mRNA]; NUS1 protein inhibits the reaction [Glucosamine results in increased splicing of XBP1 mRNA]; ursodoxicoltaurine inhibits the reaction [Glucosamine results in increased expression of XBP1 mRNA]
4-methylumbelliferone 8-carbaldehyde affects the reaction [Glucosamine results in increased expression of XBP1 protein alternative form]; 4-methylumbelliferone 8-carbaldehyde inhibits the reaction [Glucosamine results in increased splicing of XBP1 mRNA]; 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of XBP1 protein alternative form]; 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased splicing of XBP1 mRNA]; ERN1 protein affects the reaction [Glucosamine results in increased splicing of XBP1 mRNA]
4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of XBP1 mRNA]; ursodoxicoltaurine inhibits the reaction [Glucosamine results in increased expression of XBP1 mRNA]
Glucosamine results in decreased splicing of XBP1 mRNA		 CTD PMID:19383982 PMID:20165829 PMID:30602124 PMID:33812996 NCBI chr22:28,794,560...28,800,569
Ensembl chr22:28,794,555...28,800,597 		JBrowse link
G XDH xanthine dehydrogenase multiple interactions ISO [XDH protein co-treated with Hypoxanthine] inhibits the reaction [Glucosamine results in increased abundance of Proteoglycans]; [XDH protein co-treated with Hypoxanthine] inhibits the reaction [Glucosamine results in increased expression of B3GAT3 mRNA] CTD PMID:11801247 NCBI chr 2:31,334,321...31,414,742
Ensembl chr 2:31,334,321...31,414,742 		JBrowse link
G ZNF467 zinc finger protein 467 increases expression ISO Glucosamine results in increased expression of ZFP467 mRNA CTD PMID:17178593 NCBI chr 7:149,764,182...149,776,530
Ensembl chr 7:149,764,182...149,773,588 		JBrowse link
2-deoxy-D-glucose term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2M alpha-2-macroglobulin increases uptake
multiple interactions		 EXP A2M protein modified form results in increased uptake of Deoxyglucose
HSPA5 protein affects the reaction [A2M protein modified form results in increased uptake of Deoxyglucose]		 CTD PMID:25720493 NCBI chr12:9,067,708...9,116,229
Ensembl chr12:9,067,664...9,116,229 		JBrowse link
G ABCB1 ATP binding cassette subfamily B member 1 multiple interactions EXP Deoxyglucose inhibits the reaction [ABCB1 protein results in increased export of Diazinon] CTD PMID:16221533 NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323 		JBrowse link
G ABCC9 ATP binding cassette subfamily C member 9 multiple interactions ISO [Oligomycins co-treated with Deoxyglucose] results in increased activity of [KCNJ11 protein binds to ABCC9 protein]; Glyburide inhibits the reaction [[Oligomycins co-treated with Deoxyglucose] results in increased activity of [KCNJ11 protein binds to ABCC9 protein]] CTD PMID:28842488 NCBI chr12:21,797,389...21,941,426
Ensembl chr12:21,797,389...21,942,543 		JBrowse link
G ABRA actin binding Rho activating protein multiple interactions
increases uptake		 ISO CCG 1423 promotes the reaction [ABRA mutant form promotes the reaction [INS1 protein results in increased uptake of Deoxyglucose]]; CCG 1423 promotes the reaction [ABRA mutant form results in increased uptake of Deoxyglucose]; CCG 1423 promotes the reaction [INS1 protein promotes the reaction [ABRA mutant form results in increased uptake of Deoxyglucose]]; INS1 protein promotes the reaction [ABRA mutant form results in increased uptake of Deoxyglucose] CTD PMID:21393865 NCBI chr 8:106,759,483...106,770,244
Ensembl chr 8:106,759,483...106,770,244 		JBrowse link
G ADIPOQ adiponectin, C1Q and collagen domain containing multiple interactions
increases uptake		 EXP Indinavir inhibits the reaction [ADIPOQ protein modified form results in increased uptake of Deoxyglucose] CTD PMID:29991592 NCBI chr 3:186,842,710...186,858,463
Ensembl chr 3:186,842,704...186,858,463 		JBrowse link
G AGRP agouti related neuropeptide increases expression ISO Deoxyglucose results in increased expression of AGRP mRNA CTD PMID:10683841 NCBI chr16:67,482,571...67,483,547
Ensembl chr16:67,482,571...67,483,547 		JBrowse link
G AP5S1 adaptor related protein complex 5 subunit sigma 1 increases expression EXP Deoxyglucose results in increased expression of AP5S1 mRNA CTD PMID:33770205 NCBI chr20:3,820,547...3,828,838
Ensembl chr20:3,820,524...3,828,838 		JBrowse link
G APP amyloid beta precursor protein multiple interactions EXP [Sodium Azide co-treated with Deoxyglucose] affects the cleavage of and affects the localization of APP protein CTD PMID:17405930 NCBI chr21:25,880,550...26,171,128
Ensembl chr21:25,880,535...26,171,128 		JBrowse link
G ATG3 autophagy related 3 multiple interactions EXP Deoxyglucose affects the reaction [demycarosyl-3D-digitoxosylmithramycin SK affects the expression of ATG3 mRNA] CTD PMID:26079942 NCBI chr 3:112,532,510...112,561,962
Ensembl chr 3:112,532,510...112,562,046 		JBrowse link
G ATG4B autophagy related 4B cysteine peptidase multiple interactions EXP [demycarosyl-3D-digitoxosylmithramycin SK co-treated with Deoxyglucose] results in increased expression of ATG4B mRNA CTD PMID:26079942 NCBI chr 2:241,637,693...241,673,857
Ensembl chr 2:241,637,213...241,673,857 		JBrowse link
G ATG7 autophagy related 7 multiple interactions EXP ATG7 protein inhibits the reaction [Deoxyglucose results in increased cleavage of CASP3 protein]; ATG7 protein inhibits the reaction [Deoxyglucose results in increased expression of DDIT3 protein]; ATG7 protein inhibits the reaction [Deoxyglucose results in increased expression of HSPA5 protein]; ATG7 protein promotes the reaction [Deoxyglucose results in increased prenylation of MAP1LC3B protein] CTD PMID:20593179 NCBI chr 3:11,272,397...11,576,353
Ensembl chr 3:11,272,309...11,557,665 		JBrowse link
G BAX BCL2 associated X, apoptosis regulator multiple interactions
decreases expression		 EXP Deoxyglucose promotes the reaction [arsenic trioxide results in increased localization of and results in increased activity of BAX protein]; Deoxyglucose results in increased localization of and results in increased activity of BAX protein
Deoxyglucose results in decreased expression of BAX mRNA		 CTD PMID:23041229 PMID:26079942 NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798 		JBrowse link
G BCL2 BCL2 apoptosis regulator multiple interactions EXP Deoxyglucose affects the reaction [demycarosyl-3D-digitoxosylmithramycin SK affects the expression of BCL2 mRNA] CTD PMID:26079942 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128 		JBrowse link
G BCL2L1 BCL2 like 1 decreases response to substance ISO BCL2L1 protein results in decreased susceptibility to Deoxyglucose CTD PMID:10679475 NCBI chr20:31,664,452...31,723,963
Ensembl chr20:31,664,452...31,723,989 		JBrowse link
G BECN1 beclin 1 multiple interactions EXP [bafilomycin A co-treated with Deoxyglucose co-treated with demycarosyl-3D-digitoxosylmithramycin SK] results in decreased expression of BECN1 protein; [demycarosyl-3D-digitoxosylmithramycin SK co-treated with Deoxyglucose] results in increased expression of BECN1 mRNA CTD PMID:26079942 NCBI chr17:42,810,132...42,824,282
Ensembl chr17:42,810,134...42,833,350 		JBrowse link
G BID BH3 interacting domain death agonist multiple interactions EXP Deoxyglucose promotes the reaction [arsenic trioxide results in increased cleavage of and results in increased activity of BID protein]; Deoxyglucose results in increased cleavage of and results in increased activity of BID protein CTD PMID:23041229 NCBI chr22:17,734,138...17,774,665
Ensembl chr22:17,734,138...17,774,770 		JBrowse link
G CASP3 caspase 3 multiple interactions
increases activity
increases cleavage		 EXP
ISO		 ATG7 protein inhibits the reaction [Deoxyglucose results in increased cleavage of CASP3 protein]; Deoxyglucose promotes the reaction [arsenic trioxide results in increased cleavage of and results in increased activity of CASP3 protein]; Deoxyglucose results in increased cleavage of and results in increased activity of CASP3 protein
Deoxyglucose promotes the reaction [Metformin inhibits the reaction [Arsenic Trioxide results in increased expression of CASP3 protein modified form]]
Deoxyglucose results in increased activity of CASP3 protein
Corticosterone inhibits the reaction [Deoxyglucose results in increased activity of CASP3 protein]; GPX4 protein inhibits the reaction [Deoxyglucose results in increased activity of CASP3 protein]		 CTD PMID:10506188 PMID:15755911 PMID:20593179 PMID:23041229 PMID:29095437 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062 		JBrowse link
G CASP9 caspase 9 multiple interactions EXP [Deoxyglucose co-treated with Cisplatin] results in increased activity of CASP9 protein; Deoxyglucose promotes the reaction [Arsenic Trioxide results in increased cleavage of and results in increased activity of CASP9 protein]; Deoxyglucose results in increased cleavage of and results in increased activity of CASP9 protein CTD PMID:20138251 PMID:23041229 NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534 		JBrowse link
G CCDC144NL CCDC144A N-terminal like (pseudogene) decreases expression EXP Deoxyglucose results in decreased expression of CCDC144NL mRNA CTD PMID:33770205 NCBI chr17:20,863,395...20,896,163
Ensembl chr17:20,836,447...20,896,162
Ensembl chr17:20,836,447...20,896,162 		JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A multiple interactions EXP [demycarosyl-3D-digitoxosylmithramycin SK co-treated with Deoxyglucose] results in increased expression of CDKN1A mRNA CTD PMID:26079942 NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,337 		JBrowse link
G CEMIP2 cell migration inducing hyaluronidase 2 decreases expression EXP Deoxyglucose results in decreased expression of CEMIP2 mRNA CTD PMID:33770205 NCBI chr 9:71,683,366...71,769,466
Ensembl chr 9:71,683,366...71,816,690 		JBrowse link
G CHRM3 cholinergic receptor muscarinic 3 affects response to substance ISO CHRM3 protein affects the susceptibility to Deoxyglucose CTD PMID:14724830 NCBI chr 1:239,386,568...239,915,450
Ensembl chr 1:239,386,565...239,915,452 		JBrowse link
G CHUK component of inhibitor of nuclear factor kappa B kinase complex affects localization EXP Deoxyglucose analog affects the localization of CHUK protein CTD PMID:27931795 NCBI chr10:100,186,319...100,229,596
Ensembl chr10:100,188,300...100,229,596 		JBrowse link
G CTSD cathepsin D increases expression ISO Deoxyglucose results in increased expression of CTSD protein CTD PMID:20026095 NCBI chr11:1,752,755...1,763,927
Ensembl chr11:1,752,752...1,764,573 		JBrowse link
G CTSLP8 cathepsin L pseudogene 8 multiple interactions EXP Deoxyglucose inhibits the reaction [CTSLP8 protein results in decreased susceptibility to Cisplatin]; Deoxyglucose inhibits the reaction [CTSLP8 protein results in increased chemical synthesis of Lactic Acid] CTD PMID:34510316 NCBI chr 9:87,844,745...87,847,424
Ensembl chr 9:87,844,154...87,847,314 		JBrowse link
G CUL7 cullin 7 multiple interactions ISO [INS1 protein co-treated with CUL7 mutant form] results in increased uptake of Deoxyglucose CTD PMID:24219910 NCBI chr 6:43,037,617...43,053,851
Ensembl chr 6:43,037,617...43,053,943 		JBrowse link
G DDIT3 DNA damage inducible transcript 3 multiple interactions
increases expression		 EXP ATG7 protein inhibits the reaction [Deoxyglucose results in increased expression of DDIT3 protein]; Mannose inhibits the reaction [Deoxyglucose results in increased expression of DDIT3 protein] CTD PMID:20593179 NCBI chr12:57,516,588...57,520,517
Ensembl chr12:57,516,588...57,521,737 		JBrowse link
G EGFR epidermal growth factor receptor multiple interactions
increases import		 EXP AICA ribonucleotide inhibits the reaction [EGFR protein results in increased import of Deoxyglucose]
EGFR protein mutant form results in increased import of Deoxyglucose		 CTD PMID:19625624 NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628 		JBrowse link
G EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 multiple interactions EXP Deoxyglucose results in decreased phosphorylation of and results in increased expression of EIF4EBP1 protein CTD PMID:23363784 NCBI chr 8:38,030,534...38,060,365
Ensembl chr 8:38,030,534...38,060,365 		JBrowse link
G ERBB2 erb-b2 receptor tyrosine kinase 2 multiple interactions EXP [Deoxyglucose co-treated with Quercetin] results in increased ubiquitination of ERBB2 protein; Deoxyglucose inhibits the reaction [Quercetin promotes the reaction [ERBB2 protein binds to HSP90AA1 protein]] CTD PMID:18655187 NCBI chr17:39,688,094...39,728,658
Ensembl chr17:39,687,914...39,730,426 		JBrowse link
G ERRFI1 ERBB receptor feedback inhibitor 1 decreases expression EXP Deoxyglucose results in decreased expression of ERRFI1 mRNA CTD PMID:33770205 NCBI chr 1:8,011,727...8,026,309
Ensembl chr 1:8,004,404...8,026,309 		JBrowse link
G FAM117A family with sequence similarity 117 member A decreases expression EXP Deoxyglucose results in decreased expression of FAM117A mRNA CTD PMID:33770205 NCBI chr17:49,710,332...49,789,110
Ensembl chr17:49,710,332...49,789,180 		JBrowse link
G FXYD2 FXYD domain containing ion transport regulator 2 multiple interactions
increases transport		 EXP Calcium inhibits the reaction [FXYD2 protein results in increased transport of Deoxyglucose] CTD PMID:11533133 NCBI chr11:117,820,057...117,828,089
Ensembl chr11:117,800,844...117,828,698 		JBrowse link
G G3BP1 G3BP stress granule assembly factor 1 multiple interactions EXP Deoxyglucose inhibits the reaction [G3BP1 protein results in increased abundance of Lactic Acid]; Deoxyglucose inhibits the reaction [G3BP1 protein results in increased expression of HK2 protein]; Deoxyglucose inhibits the reaction [G3BP1 protein results in increased expression of LDHA protein]; Deoxyglucose inhibits the reaction [G3BP1 protein results in increased expression of PKM protein]; Deoxyglucose inhibits the reaction [G3BP1 protein results in increased uptake of Glucose] CTD PMID:35945655 NCBI chr 5:151,771,954...151,812,785
Ensembl chr 5:151,771,045...151,812,911 		JBrowse link
G GALR1 galanin receptor 1 increases expression ISO Deoxyglucose results in increased expression of GALR1 mRNA CTD PMID:9858361 PMID:9928191 NCBI chr18:77,249,848...77,277,900
Ensembl chr18:77,249,848...77,277,900 		JBrowse link
G GCG glucagon multiple interactions
increases secretion		 ISO Capsaicin inhibits the reaction [Deoxyglucose results in increased secretion of GCG protein] CTD PMID:1378463 NCBI chr 2:162,142,882...162,152,247
Ensembl chr 2:162,142,882...162,152,404 		JBrowse link
G GPX4 glutathione peroxidase 4 multiple interactions ISO GPX4 protein inhibits the reaction [Deoxyglucose results in increased activity of CASP3 protein] CTD PMID:10506188 NCBI chr19:1,103,994...1,106,779
Ensembl chr19:1,103,982...1,106,791 		JBrowse link
G GSK3B glycogen synthase kinase 3 beta multiple interactions EXP Deoxyglucose inhibits the reaction [arsenic trioxide results in increased phosphorylation of GSK3B protein]; Deoxyglucose inhibits the reaction [Fenretinide results in increased phosphorylation of GSK3B protein] CTD PMID:25246272 NCBI chr 3:119,821,321...120,094,447
Ensembl chr 3:119,821,321...120,094,994 		JBrowse link
G H2AX H2A.X variant histone decreases expression EXP Deoxyglucose results in decreased expression of H2AX protein CTD PMID:23363784 NCBI chr11:119,093,874...119,095,465
Ensembl chr11:119,093,874...119,095,465 		JBrowse link
G HK2 hexokinase 2 multiple interactions EXP [Lactic Acid co-treated with Deoxyglucose] inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of HK2 protein]; Deoxyglucose inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of HK2 protein]; Deoxyglucose inhibits the reaction [G3BP1 protein results in increased expression of HK2 protein]; Deoxyglucose inhibits the reaction [HMGA2 protein results in increased expression of HK2 protein]; Deoxyglucose results in decreased expression of and results in decreased activity of HK2 protein CTD PMID:32619556 PMID:34481905 PMID:35945655 PMID:36336208 NCBI chr 2:74,834,127...74,893,359
Ensembl chr 2:74,834,127...74,893,359 		JBrowse link
G HMGA2 high mobility group AT-hook 2 multiple interactions EXP Deoxyglucose inhibits the reaction [HMGA2 protein results in decreased expression of COX4 protein]; Deoxyglucose inhibits the reaction [HMGA2 protein results in decreased expression of ND1 protein]; Deoxyglucose inhibits the reaction [HMGA2 protein results in increased expression of HK2 protein]; Deoxyglucose inhibits the reaction [HMGA2 protein results in increased expression of MMP2 protein]; Deoxyglucose inhibits the reaction [HMGA2 protein results in increased expression of MMP9 protein] CTD PMID:34481905 NCBI chr12:65,824,460...65,966,291
Ensembl chr12:65,824,460...65,966,291 		JBrowse link
G HMOX1 heme oxygenase 1 multiple interactions EXP Deoxyglucose inhibits the reaction [arsenic trioxide results in increased expression of HMOX1 protein]; Deoxyglucose inhibits the reaction [Fenretinide results in increased expression of HMOX1 protein] CTD PMID:25246272 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214 		JBrowse link
G HSP90AA1 heat shock protein 90 alpha family class A member 1 multiple interactions EXP Deoxyglucose inhibits the reaction [Quercetin promotes the reaction [ERBB2 protein binds to HSP90AA1 protein]] CTD PMID:18655187 NCBI chr14:102,080,742...102,139,749
Ensembl chr14:102,080,742...102,139,699 		JBrowse link
G HSP90B1 heat shock protein 90 beta family member 1 multiple interactions
increases expression		 EXP 4-Quinolones analog inhibits the reaction [Deoxyglucose results in increased expression of HSP90B1 protein] CTD PMID:31022492 NCBI chr12:103,930,410...103,947,926
Ensembl chr12:103,930,107...103,953,931 		JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 multiple interactions
increases expression		 EXP 4-Quinolones analog inhibits the reaction [Deoxyglucose results in increased expression of HSPA5 mRNA]; 4-Quinolones analog inhibits the reaction [Deoxyglucose results in increased expression of HSPA5 protein]; ATG7 protein inhibits the reaction [Deoxyglucose results in increased expression of HSPA5 protein]; HSPA5 protein affects the reaction [A2M protein modified form results in increased uptake of Deoxyglucose]; HSPA5 protein affects the reaction [INS protein results in increased uptake of Deoxyglucose]; Mannose inhibits the reaction [Deoxyglucose results in increased expression of HSPA5 protein]; Oxygen deficiency inhibits the reaction [Deoxyglucose results in increased expression of HSPA5 protein]
Deoxyglucose results in increased expression of HSPA5 mRNA; Deoxyglucose results in increased expression of HSPA5 protein		 CTD PMID:20593179 PMID:25720493 PMID:31022492 NCBI chr 9:125,234,853...125,241,343
Ensembl chr 9:125,234,853...125,241,382 		JBrowse link
G HTRA2 HtrA serine peptidase 2 multiple interactions
decreases localization		 EXP Deoxyglucose promotes the reaction [arsenic trioxide results in decreased localization of HTRA2 protein]
Deoxyglucose results in decreased localization of HTRA2 protein		 CTD PMID:23041229 NCBI chr 2:74,529,405...74,533,556
Ensembl chr 2:74,529,596...74,533,350 		JBrowse link
G IGF1R insulin like growth factor 1 receptor multiple interactions EXP Deoxyglucose results in increased phosphorylation of and results in increased activity of IGF1R protein CTD PMID:23041229 NCBI chr15:98,648,539...98,964,530
Ensembl chr15:98,648,539...98,964,530 		JBrowse link
G IL1B interleukin 1 beta decreases response to substance
multiple interactions		 EXP
ISO		 Deoxyglucose results in decreased susceptibility to IL1B protein
Deoxyglucose inhibits the reaction [bisphenol F results in increased secretion of IL1B protein]
Deoxyglucose inhibits the reaction [IL1B protein results in increased expression of MMP13 protein]		 CTD PMID:21211511 PMID:34147605 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL6 interleukin 6 multiple interactions ISO Deoxyglucose inhibits the reaction [bisphenol F results in increased secretion of IL6 protein] CTD PMID:34147605 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G INS insulin increases uptake
multiple interactions		 EXP
ISO		 INS protein results in increased uptake of Deoxyglucose; INS results in increased uptake of Deoxyglucose
METRNL protein inhibits the reaction [INS protein results in increased uptake of Deoxyglucose]; PPARA protein promotes the reaction [GW 7647 promotes the reaction [INS protein results in increased uptake of Deoxyglucose]]
3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Palmitic Acid inhibits the reaction [INS protein results in increased uptake of Deoxyglucose]]; 4-phenylbutyric acid inhibits the reaction [Glucosamine inhibits the reaction [INS results in increased uptake of Deoxyglucose]]; Glucosamine inhibits the reaction [INS results in increased uptake of Deoxyglucose]; GW 7647 promotes the reaction [INS protein results in increased uptake of Deoxyglucose]; HSPA5 protein affects the reaction [INS protein results in increased uptake of Deoxyglucose]; Palmitates inhibits the reaction [INS protein results in increased uptake of Deoxyglucose]; Palmitic Acid inhibits the reaction [INS protein results in increased uptake of Deoxyglucose]; SLC2A1 protein inhibits the reaction [INS protein results in increased uptake of Deoxyglucose]; tin protoporphyrin IX inhibits the reaction [3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Palmitic Acid inhibits the reaction [INS protein results in increased uptake of Deoxyglucose]]]; TNF protein inhibits the reaction [INS protein results in increased uptake of Deoxyglucose]; Troglitazone inhibits the reaction [TNF protein inhibits the reaction [INS protein results in increased uptake of Deoxyglucose]]; ursodoxicoltaurine inhibits the reaction [Glucosamine inhibits the reaction [INS results in increased uptake of Deoxyglucose]]		 CTD PMID:2173694 PMID:16483873 PMID:20165829 PMID:21324916 PMID:25720493 More... NCBI chr11:2,159,779...2,161,209
Ensembl chr11:2,159,779...2,161,221 		JBrowse link
G INS-IGF2 INS-IGF2 readthrough increases uptake
increases secretion
affects transport
increases transport
multiple interactions		 ISO INS1 protein results in increased uptake of Deoxyglucose; INS1 results in increased uptake of Deoxyglucose
Deoxyglucose results in increased secretion of INS1 protein
INS1 protein affects the transport of Deoxyglucose
INS1 protein results in increased transport of Deoxyglucose
4-phenylbutyric acid inhibits the reaction [Glucosamine inhibits the reaction [INS1 results in increased uptake of Deoxyglucose]]; CCG 1423 promotes the reaction [ABRA mutant form promotes the reaction [INS1 protein results in increased uptake of Deoxyglucose]]; CCG 1423 promotes the reaction [INS1 protein promotes the reaction [ABRA mutant form results in increased uptake of Deoxyglucose]]; CCG 1423 promotes the reaction [INS1 protein results in increased uptake of Deoxyglucose]; Diethylhexyl Phthalate inhibits the reaction [INS1 protein results in increased uptake of Deoxyglucose]; Glucosamine inhibits the reaction [INS1 protein results in increased uptake of Deoxyglucose]; Glucosamine inhibits the reaction [INS1 results in increased uptake of Deoxyglucose]; Glucose inhibits the reaction [INS1 protein results in increased uptake of Deoxyglucose]; glyceryl 2-arachidonate promotes the reaction [INS1 protein results in increased uptake of Deoxyglucose]; INS1 protein promotes the reaction [ABRA mutant form results in increased uptake of Deoxyglucose]; INS1 protein promotes the reaction [CCG 1423 results in increased uptake of Deoxyglucose]; mono-(2-ethylhexyl)phthalate inhibits the reaction [INS1 protein results in increased uptake of Deoxyglucose]; N-(3-methoxyphenyl)-4-chlorocinnamanilide inhibits the reaction [glyceryl 2-arachidonate promotes the reaction [INS1 protein results in increased uptake of Deoxyglucose]]; oxophenylarsine inhibits the reaction [INS1 protein results in increased uptake of Deoxyglucose]; Palmitic Acid inhibits the reaction [INS1 protein results in increased uptake of Deoxyglucose]; Quercetin inhibits the reaction [Palmitic Acid inhibits the reaction [INS1 protein results in increased uptake of Deoxyglucose]]; Quercetin inhibits the reaction [TNF protein inhibits the reaction [INS1 protein results in increased uptake of Deoxyglucose]]; Quercetin promotes the reaction [INS1 protein results in increased uptake of Deoxyglucose]; Raffinose promotes the reaction [INS1 protein results in increased uptake of Deoxyglucose]; SLC2A4 promotes the reaction [INS1 protein results in increased uptake of Deoxyglucose]; TNF protein inhibits the reaction [INS1 protein results in increased uptake of Deoxyglucose]; ursodoxicoltaurine inhibits the reaction [Glucosamine inhibits the reaction [INS1 results in increased uptake of Deoxyglucose]]
[INS1 protein co-treated with CUL7 mutant form] results in increased uptake of Deoxyglucose; acetylaminophenylarsine oxide inhibits the reaction [INS1 protein results in increased transport of Deoxyglucose]; Apigenin inhibits the reaction [INS1 protein results in increased uptake of Deoxyglucose]; Dimercaprol inhibits the reaction [oxophenylarsine inhibits the reaction [INS1 protein results in increased transport of Deoxyglucose]]; Dimercaprol inhibits the reaction [oxophenylarsine inhibits the reaction [INS1 protein results in increased uptake of Deoxyglucose]]; Dimercaprol inhibits the reaction [p-aminophenylarsine oxide inhibits the reaction [INS1 protein results in increased transport of Deoxyglucose]]; dorsomorphin inhibits the reaction [Quercetin inhibits the reaction [INS1 protein results in increased uptake of Deoxyglucose]]; epigallocatechin gallate inhibits the reaction [INS1 protein results in increased uptake of Deoxyglucose]; fisetin inhibits the reaction [INS1 protein results in increased uptake of Deoxyglucose]; Genistein inhibits the reaction [INS1 protein results in increased uptake of Deoxyglucose]; Genistein inhibits the reaction [Raffinose promotes the reaction [INS1 protein results in increased uptake of Deoxyglucose]]; kaempferol inhibits the reaction [INS1 protein results in increased uptake of Deoxyglucose]; Luteolin inhibits the reaction [INS1 protein results in increased uptake of Deoxyglucose]; oxophenylarsine inhibits the reaction [INS1 protein results in increased transport of Deoxyglucose]; oxophenylarsine inhibits the reaction [INS1 protein results in increased uptake of Deoxyglucose]; p-aminophenylarsine oxide inhibits the reaction [INS1 protein results in increased transport of Deoxyglucose]; Quercetin inhibits the reaction [INS1 protein results in increased uptake of Deoxyglucose]; Quercetin inhibits the reaction [TNF protein inhibits the reaction [INS1 protein results in increased uptake of Deoxyglucose]]; Raffinose promotes the reaction [INS1 protein results in increased uptake of Deoxyglucose]; Ro 31-8220 inhibits the reaction [INS1 protein results in increased uptake of Deoxyglucose]; Silybin inhibits the reaction [INS1 protein results in increased uptake of Deoxyglucose]; theaflavin inhibits the reaction [INS1 protein results in increased uptake of Deoxyglucose]; TNF protein inhibits the reaction [INS1 protein results in increased uptake of Deoxyglucose]; tyrphostin 25 inhibits the reaction [INS1 protein results in increased uptake of Deoxyglucose]; Wortmannin inhibits the reaction [Raffinose promotes the reaction [INS1 protein results in increased uptake of Deoxyglucose]]		 CTD PMID:1378463 PMID:1536656 PMID:1847587 PMID:1918056 PMID:2202293 More... NCBI chr11:2,129,117...2,161,209
Ensembl chr11:2,132,538...2,161,209 		JBrowse link
G ITGB1 integrin subunit beta 1 decreases expression EXP Deoxyglucose analog results in decreased expression of ITGB1 protein CTD PMID:27931795 NCBI chr10:32,900,318...32,958,230
Ensembl chr10:32,887,273...33,005,792 		JBrowse link
G JADE2 jade family PHD finger 2 increases expression EXP Deoxyglucose results in increased expression of JADE2 mRNA CTD PMID:33770205 NCBI chr 5:134,523,952...134,583,227
Ensembl chr 5:134,524,312...134,583,230 		JBrowse link
G KCNH2 potassium voltage-gated channel subfamily H member 2 multiple interactions
decreases activity		 EXP [Deoxyglucose co-treated with Glucose deficiency] results in decreased activity of KCNH2 protein; Deoxyglucose inhibits the reaction [Glucose results in decreased activity of KCNH2 protein]; Deoxyglucose promotes the reaction [Glucose deficiency results in decreased activity of KCNH2 protein]; Pyruvic Acid inhibits the reaction [[Deoxyglucose co-treated with Glucose deficiency] results in decreased activity of KCNH2 protein]
Deoxyglucose results in decreased activity of KCNH2 protein		 CTD PMID:12531891 NCBI chr 7:150,944,961...150,978,321
Ensembl chr 7:150,944,961...150,978,321 		JBrowse link
G KCNJ11 potassium inwardly rectifying channel subfamily J member 11 multiple interactions ISO [Oligomycins co-treated with Deoxyglucose] results in increased activity of [KCNJ11 protein binds to ABCC9 protein]; Glyburide inhibits the reaction [[Oligomycins co-treated with Deoxyglucose] results in increased activity of [KCNJ11 protein binds to ABCC9 protein]] CTD PMID:28842488 NCBI chr11:17,385,248...17,389,346
Ensembl chr11:17,365,172...17,389,331 		JBrowse link
G KLHL42 kelch like family member 42 increases expression EXP Deoxyglucose results in increased expression of KLHL42 mRNA CTD PMID:33770205 NCBI chr12:27,780,233...27,803,040
Ensembl chr12:27,780,048...27,803,040 		JBrowse link
G LDHA lactate dehydrogenase A multiple interactions EXP Deoxyglucose inhibits the reaction [G3BP1 protein results in increased expression of LDHA protein] CTD PMID:35945655 NCBI chr11:18,394,563...18,408,425
Ensembl chr11:18,394,560...18,408,425 		JBrowse link
G LEP leptin multiple interactions
decreases secretion		 ISO [Deoxyglucose results in decreased abundance of Adenosine Triphosphate] which results in decreased secretion of LEP protein
Deoxyglucose results in decreased secretion of LEP protein		 CTD PMID:10780946 NCBI chr 7:128,241,278...128,257,629
Ensembl chr 7:128,241,278...128,257,629 		JBrowse link
G LIPH lipase H decreases expression EXP Deoxyglucose results in decreased expression of LIPH mRNA CTD PMID:33770205 NCBI chr 3:185,506,262...185,552,588
Ensembl chr 3:185,506,262...185,552,588 		JBrowse link
G MAP1LC3A microtubule associated protein 1 light chain 3 alpha multiple interactions EXP Deoxyglucose affects the reaction [demycarosyl-3D-digitoxosylmithramycin SK affects the expression of MAP1LC3A mRNA] CTD PMID:26079942 NCBI chr20:34,546,844...34,560,345
Ensembl chr20:34,546,854...34,560,345 		JBrowse link
G MAP1LC3B microtubule associated protein 1 light chain 3 beta multiple interactions
increases prenylation		 EXP ATG7 protein promotes the reaction [Deoxyglucose results in increased prenylation of MAP1LC3B protein]; Mannose inhibits the reaction [Deoxyglucose results in increased prenylation of MAP1LC3B protein]; Oxygen deficiency inhibits the reaction [Deoxyglucose results in increased prenylation of MAP1LC3B protein] CTD PMID:20593179 NCBI chr16:87,392,336...87,404,774
Ensembl chr16:87,383,953...87,404,779 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 multiple interactions EXP Arsenic Trioxide inhibits the reaction [Deoxyglucose results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Deoxyglucose results in increased phosphorylation of and results in increased activity of MAPK1 protein; PQ 401 inhibits the reaction [Deoxyglucose results in increased phosphorylation of and results in increased activity of MAPK1 protein]; U 0126 inhibits the reaction [Deoxyglucose results in increased phosphorylation of and results in increased activity of MAPK1 protein] CTD PMID:23041229 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 multiple interactions ISO
EXP		 MAPK3 protein affects the reaction [AICA ribonucleotide results in increased uptake of Deoxyglucose]
arsenic trioxide inhibits the reaction [Deoxyglucose results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Deoxyglucose results in increased phosphorylation of and results in increased activity of MAPK3 protein; PQ 401 inhibits the reaction [Deoxyglucose results in increased phosphorylation of and results in increased activity of MAPK3 protein]; U 0126 inhibits the reaction [Deoxyglucose results in increased phosphorylation of and results in increased activity of MAPK3 protein]		 CTD PMID:11978788 PMID:23041229 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506 		JBrowse link
G MEPCE methylphosphate capping enzyme increases expression EXP Deoxyglucose results in increased expression of MEPCE mRNA CTD PMID:33770205 NCBI chr 7:100,428,790...100,434,118
Ensembl chr 7:100,428,322...100,434,126 		JBrowse link
G METRNL meteorin like, glial cell differentiation regulator multiple interactions ISO METRNL protein inhibits the reaction [INS protein results in increased uptake of Deoxyglucose] CTD PMID:30213948 NCBI chr17:83,079,609...83,095,122
Ensembl chr17:83,079,609...83,095,122 		JBrowse link
G MMP13 matrix metallopeptidase 13 multiple interactions
decreases expression		 EXP Deoxyglucose inhibits the reaction [IL1B protein results in increased expression of MMP13 protein]; Deoxyglucose inhibits the reaction [TNF protein results in increased expression of MMP13 protein]
Deoxyglucose analog results in decreased expression of MMP13 protein		 CTD PMID:21211511 PMID:27931795 NCBI chr11:102,942,995...102,955,732
Ensembl chr11:102,942,995...102,955,732 		JBrowse link
G MMP2 matrix metallopeptidase 2 multiple interactions EXP Deoxyglucose inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of MMP2 protein]; Deoxyglucose inhibits the reaction [HMGA2 protein results in increased expression of MMP2 protein] CTD PMID:34481905 NCBI chr16:55,478,830...55,506,691
Ensembl chr16:55,389,700...55,506,691 		JBrowse link
G MMP9 matrix metallopeptidase 9 decreases expression
multiple interactions		 EXP Deoxyglucose analog results in decreased expression of MMP9 protein
Deoxyglucose inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of MMP9 protein]; Deoxyglucose inhibits the reaction [HMGA2 protein results in increased expression of MMP9 protein]		 CTD PMID:27931795 PMID:34481905 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561 		JBrowse link
G MT-ND1 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 1 multiple interactions EXP Deoxyglucose inhibits the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of ND1 protein]; Deoxyglucose inhibits the reaction [HMGA2 protein results in decreased expression of ND1 protein] CTD PMID:34481905 NCBI chr MT:3,307...4,262
Ensembl chr MT:3,307...4,262 		JBrowse link
G MTOR mechanistic target of rapamycin kinase multiple interactions EXP Deoxyglucose results in decreased phosphorylation of and results in increased expression of MTOR protein; Deoxyglucose results in increased phosphorylation of and results in increased activity of MTOR protein CTD PMID:23041229 PMID:23363784 NCBI chr 1:11,106,535...11,262,551
Ensembl chr 1:11,106,535...11,262,556 		JBrowse link
G MXI1 MAX interactor 1, dimerization protein decreases expression EXP Deoxyglucose results in decreased expression of MXI1 mRNA CTD PMID:33770205 NCBI chr10:110,207,605...110,287,365
Ensembl chr10:110,207,605...110,287,365 		JBrowse link
G MYO1E myosin IE decreases expression EXP Deoxyglucose results in decreased expression of MYO1E mRNA CTD PMID:33770205 NCBI chr15:59,132,434...59,372,871
Ensembl chr15:59,132,434...59,372,871 		JBrowse link
G NFKB1 nuclear factor kappa B subunit 1 multiple interactions
decreases expression		 EXP [demycarosyl-3D-digitoxosylmithramycin SK co-treated with Deoxyglucose] affects the expression of NFKB1 mRNA
Deoxyglucose results in decreased expression of NFKB1 mRNA		 CTD PMID:26079942 NCBI chr 4:102,501,359...102,617,302
Ensembl chr 4:102,501,330...102,617,302 		JBrowse link
G NOS2 nitric oxide synthase 2 multiple interactions EXP Deoxyglucose promotes the reaction [STO 609 inhibits the reaction [Histamine results in increased phosphorylation of NOS2 protein]] CTD PMID:21145922 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529 		JBrowse link
G NPY neuropeptide Y increases expression ISO Deoxyglucose results in increased expression of NPY mRNA CTD PMID:10683841 NCBI chr 7:24,284,190...24,291,862
Ensembl chr 7:24,284,188...24,291,862 		JBrowse link
G OAT ornithine aminotransferase multiple interactions ISO Deoxyglucose inhibits the reaction [Cyclic AMP results in increased activity of OAT protein] CTD PMID:2827574 NCBI chr10:124,397,303...124,418,923
Ensembl chr10:124,397,303...124,418,976 		JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 multiple interactions
increases cleavage		 EXP
ISO		 Deoxyglucose inhibits the reaction [arsenic trioxide results in increased cleavage of PARP1 protein]; Deoxyglucose inhibits the reaction [Fenretinide results in increased cleavage of PARP1 protein]
Deoxyglucose promotes the reaction [Metformin inhibits the reaction [Arsenic Trioxide results in increased expression of PARP1 protein modified form]]
Deoxyglucose results in increased cleavage of PARP1 protein		 CTD PMID:25246272 PMID:29095437 NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154 		JBrowse link
G PKM pyruvate kinase M1/2 multiple interactions EXP Deoxyglucose inhibits the reaction [G3BP1 protein results in increased expression of PKM protein] CTD PMID:35945655 NCBI chr15:72,199,029...72,231,591
Ensembl chr15:72,199,029...72,231,819 		JBrowse link
G PMCH pro-melanin concentrating hormone increases expression ISO Deoxyglucose results in increased expression of PMCH mRNA CTD PMID:10683841 NCBI chr12:102,196,459...102,197,833
Ensembl chr12:102,196,459...102,197,833 		JBrowse link
G PPARA peroxisome proliferator activated receptor alpha multiple interactions ISO PPARA protein promotes the reaction [GW 7647 promotes the reaction [INS protein results in increased uptake of Deoxyglucose]] CTD PMID:21324916 NCBI chr22:46,150,526...46,243,756
Ensembl chr22:46,150,521...46,243,755 		JBrowse link
G PPARG peroxisome proliferator activated receptor gamma affects uptake
increases uptake		 ISO PPARG protein affects the uptake of Deoxyglucose
PPARG gene polymorphism results in increased uptake of Deoxyglucose		 CTD PMID:18083318 NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356 		JBrowse link
G PPP3CA protein phosphatase 3 catalytic subunit alpha decreases response to substance ISO PPP3CA protein results in decreased susceptibility to Deoxyglucose CTD PMID:10679475 NCBI chr 4:101,023,418...101,347,526
Ensembl chr 4:101,023,409...101,348,278 		JBrowse link
G PYM1 PYM homolog 1, exon junction complex associated factor increases expression EXP Deoxyglucose results in increased expression of PYM1 mRNA CTD PMID:33770205 NCBI chr12:55,901,413...55,927,894
Ensembl chr12:55,901,413...55,932,618 		JBrowse link
G RAF1 Raf-1 proto-oncogene, serine/threonine kinase multiple interactions ISO RAF1 protein affects the reaction [AICA ribonucleotide results in increased uptake of Deoxyglucose] CTD PMID:11978788 NCBI chr 3:12,583,601...12,664,117
Ensembl chr 3:12,582,101...12,664,201 		JBrowse link
G RNF24 ring finger protein 24 decreases expression EXP Deoxyglucose results in decreased expression of RNF24 mRNA CTD PMID:33770205 NCBI chr20:3,927,311...4,015,558
Ensembl chr20:3,927,309...4,015,558 		JBrowse link
G RPS6 ribosomal protein S6 decreases phosphorylation EXP Deoxyglucose results in decreased phosphorylation of RPS6 protein CTD PMID:23363784 NCBI chr 9:19,375,715...19,380,236
Ensembl chr 9:19,375,715...19,380,236 		JBrowse link
G RPS6KB1 ribosomal protein S6 kinase B1 decreases phosphorylation
multiple interactions		 EXP Deoxyglucose results in decreased phosphorylation of RPS6KB1 protein
Deoxyglucose results in increased phosphorylation of and results in increased activity of RPS6KB1 protein; oxophenylarsine inhibits the reaction [Deoxyglucose results in decreased phosphorylation of RPS6KB1 protein]		 CTD PMID:16183647 PMID:23041229 NCBI chr17:59,893,121...59,950,574
Ensembl chr17:59,893,046...59,950,574 		JBrowse link
G SERPINB5 serpin family B member 5 increases expression EXP Deoxyglucose analog results in increased expression of SERPINB5 protein CTD PMID:27931795 NCBI chr18:63,476,958...63,505,085
Ensembl chr18:63,476,958...63,505,085 		JBrowse link
G SLC16A1 solute carrier family 16 member 1 multiple interactions EXP [Lactic Acid co-treated with Deoxyglucose] promotes the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of SLC16A1 protein] CTD PMID:36336208 NCBI chr 1:112,911,847...112,956,196
Ensembl chr 1:112,911,847...112,957,593 		JBrowse link
G SLC2A1 solute carrier family 2 member 1 multiple interactions
increases uptake		 ISO
EXP		 [arsenite affects the localization of SLC2A1 protein] which results in increased uptake of Deoxyglucose
SLC2A1 protein results in increased uptake of Deoxyglucose
[Deoxyglucose results in increased abundance of Glucose] which affects the localization of SLC2A1 protein; [sodium arsenite results in increased abundance of Arsenic] inhibits the reaction [[Deoxyglucose results in increased abundance of Glucose] which affects the localization of SLC2A1 protein]; SLC2A1 protein inhibits the reaction [INS protein results in increased uptake of Deoxyglucose]		 CTD PMID:2173694 PMID:14511371 PMID:31398423 NCBI chr 1:42,925,353...42,958,868
Ensembl chr 1:42,925,353...42,958,893 		JBrowse link
G SLC2A2 solute carrier family 2 member 2 multiple interactions
increases transport		 EXP Cytochalasin B inhibits the reaction [SLC2A2 protein results in increased transport of Deoxyglucose]; Fructose inhibits the reaction [SLC2A2 protein results in increased transport of Deoxyglucose]; Glucose inhibits the reaction [SLC2A2 protein results in increased transport of Deoxyglucose]; Maltose inhibits the reaction [SLC2A2 protein results in increased transport of Deoxyglucose] CTD PMID:8457197 NCBI chr 3:170,996,347...171,026,720
Ensembl chr 3:170,996,347...171,026,743 		JBrowse link
G SLC2A3 solute carrier family 2 member 3 multiple interactions
increases transport		 EXP Cytochalasin B inhibits the reaction [SLC2A3 protein results in increased transport of Deoxyglucose]; Galactose inhibits the reaction [SLC2A3 protein results in increased transport of Deoxyglucose]; Glucose inhibits the reaction [SLC2A3 protein results in increased transport of Deoxyglucose]; Maltose inhibits the reaction [SLC2A3 protein results in increased transport of Deoxyglucose] CTD PMID:8457197 NCBI chr12:7,919,230...7,936,187
Ensembl chr12:7,919,230...8,019,007 		JBrowse link
G SLC2A4 solute carrier family 2 member 4 multiple interactions
increases uptake		 ISO 2-chloro-5-nitrobenzanilide inhibits the reaction [mangiferin promotes the reaction [SLC2A4 protein results in increased uptake of Deoxyglucose]]; [arsenite affects the localization of SLC2A4 protein] which results in increased uptake of Deoxyglucose; mangiferin promotes the reaction [SLC2A4 protein results in increased uptake of Deoxyglucose]; Plant Extracts promotes the reaction [SLC2A4 protein results in increased uptake of Deoxyglucose]
[Indinavir results in decreased activity of SLC2A4 protein] inhibits the reaction [resveratrol results in increased uptake of Deoxyglucose]; SLC2A4 promotes the reaction [INS1 protein results in increased uptake of Deoxyglucose]; SLC2A4 protein promotes the reaction [resveratrol results in increased uptake of Deoxyglucose]		 CTD PMID:14511371 PMID:18601907 PMID:19477051 PMID:20206685 NCBI chr17:7,281,718...7,288,257
Ensembl chr17:7,281,718...7,288,257 		JBrowse link
G SLC2A8 solute carrier family 2 member 8 increases uptake ISO SLC2A8 protein results in increased uptake of Deoxyglucose CTD PMID:23396969 NCBI chr 9:127,397,169...127,407,898
Ensembl chr 9:127,397,138...127,408,424 		JBrowse link
G SLC7A11 solute carrier family 7 member 11 decreases expression EXP Deoxyglucose results in decreased expression of SLC7A11 protein CTD PMID:37927237 NCBI chr 4:138,164,097...138,312,671
Ensembl chr 4:138,164,097...138,242,349 		JBrowse link
G SMIM14 small integral membrane protein 14 decreases expression EXP Deoxyglucose results in decreased expression of SMIM14 mRNA CTD PMID:33770205 NCBI chr 4:39,546,336...39,638,865
Ensembl chr 4:39,546,336...39,638,902 		JBrowse link
G SND1 staphylococcal nuclease and tudor domain containing 1 decreases expression EXP Deoxyglucose results in decreased expression of SND1 protein CTD PMID:37927237 NCBI chr 7:127,652,194...128,092,593
Ensembl chr 7:127,652,194...128,092,609 		JBrowse link
G SNHG1 small nucleolar RNA host gene 1 multiple interactions EXP Deoxyglucose affects the reaction [SNHG1 protein results in decreased susceptibility to Sorafenib] CTD PMID:37927237 NCBI chr11:62,851,978...62,855,885
Ensembl chr11:62,851,978...62,855,953 		JBrowse link
G SOD2 superoxide dismutase 2 multiple interactions EXP Deoxyglucose inhibits the reaction [manganese chloride results in increased expression of SOD2 mRNA]; Deoxyglucose inhibits the reaction [manganese chloride results in increased expression of SOD2 protein] CTD PMID:10328827 NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529 		JBrowse link
G SQSTM1 sequestosome 1 multiple interactions EXP [bafilomycin A co-treated with Deoxyglucose co-treated with demycarosyl-3D-digitoxosylmithramycin SK] affects the expression of SQSTM1 protein; [bafilomycin A co-treated with Deoxyglucose] affects the expression of SQSTM1 protein; Deoxyglucose inhibits the reaction [demycarosyl-3D-digitoxosylmithramycin SK results in decreased expression of SQSTM1 mRNA]; Deoxyglucose promotes the reaction [demycarosyl-3D-digitoxosylmithramycin SK results in decreased expression of SQSTM1 mRNA] CTD PMID:26079942 NCBI chr 5:179,806,393...179,838,078
Ensembl chr 5:179,806,398...179,838,078 		JBrowse link
G SREBF1 sterol regulatory element binding transcription factor 1 increases expression ISO Deoxyglucose results in increased expression of SREBF1 mRNA CTD PMID:10913129 NCBI chr17:17,811,334...17,836,986
Ensembl chr17:17,810,399...17,837,002 		JBrowse link
G SRGAP3 SLIT-ROBO Rho GTPase activating protein 3 decreases expression EXP Deoxyglucose results in decreased expression of SRGAP3 mRNA CTD PMID:33770205 NCBI chr 3:8,980,591...9,363,027
Ensembl chr 3:8,980,591...9,363,053 		JBrowse link
G STK11 serine/threonine kinase 11 decreases phosphorylation EXP Deoxyglucose results in decreased phosphorylation of STK11 protein CTD PMID:23041229 NCBI chr19:1,205,778...1,228,431
Ensembl chr19:1,177,558...1,228,431 		JBrowse link
G TENT4B terminal nucleotidyltransferase 4B decreases expression EXP Deoxyglucose results in decreased expression of TENT4B mRNA CTD PMID:33770205 NCBI chr16:50,152,911...50,235,310
Ensembl chr16:50,152,911...50,235,310 		JBrowse link
G TMCC3 transmembrane and coiled-coil domain family 3 decreases expression EXP Deoxyglucose results in decreased expression of TMCC3 mRNA CTD PMID:33770205 NCBI chr12:94,567,122...94,650,557
Ensembl chr12:94,567,122...94,650,557 		JBrowse link
G TMEM250 transmembrane protein 250 increases expression EXP Deoxyglucose results in increased expression of TMEM250 mRNA CTD PMID:33770205 NCBI chr 9:136,107,767...136,118,875
Ensembl chr 9:136,114,581...136,118,875 		JBrowse link
G TMEM87A transmembrane protein 87A increases expression EXP Deoxyglucose results in increased expression of TMEM87A mRNA CTD PMID:33770205 NCBI chr15:42,210,447...42,273,584
Ensembl chr15:42,210,447...42,273,534 		JBrowse link
G TNF tumor necrosis factor decreases expression
multiple interactions
decreases response to substance		 ISO
EXP		 Deoxyglucose results in decreased expression of TNF protein
Quercetin inhibits the reaction [TNF protein inhibits the reaction [INS1 protein results in increased uptake of Deoxyglucose]]; TNF protein inhibits the reaction [INS1 protein results in increased uptake of Deoxyglucose]
Deoxyglucose inhibits the reaction [bisphenol F results in increased secretion of TNF protein]; Quercetin inhibits the reaction [TNF protein inhibits the reaction [INS1 protein results in increased uptake of Deoxyglucose]]; TNF protein inhibits the reaction [INS1 protein results in increased uptake of Deoxyglucose]
Deoxyglucose results in decreased susceptibility to TNF protein
Deoxyglucose inhibits the reaction [TNF protein results in increased expression of MMP13 protein]; TNF protein inhibits the reaction [INS protein results in increased uptake of Deoxyglucose]; Troglitazone inhibits the reaction [TNF protein inhibits the reaction [INS protein results in increased uptake of Deoxyglucose]]		 CTD PMID:16483873 PMID:21211511 PMID:21778228 PMID:22713545 PMID:23439570 More... NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TP53 tumor protein p53 multiple interactions EXP [Deoxyglucose co-treated with demycarosyl-3D-digitoxosylmithramycin SK] results in increased expression of TP53 mRNA; Deoxyglucose promotes the reaction [demycarosyl-3D-digitoxosylmithramycin SK results in increased expression of TP53 mRNA]; TP53 protein inhibits the reaction [Deoxyglucose results in decreased abundance of Adenosine Triphosphate] CTD PMID:21042727 PMID:26079942 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,546 		JBrowse link
G XIAP X-linked inhibitor of apoptosis multiple interactions EXP [arsenic trioxide co-treated with Deoxyglucose] results in decreased expression of XIAP protein CTD PMID:23041229 NCBI chr  X:123,859,708...123,913,972
Ensembl chr  X:123,859,712...123,913,972 		JBrowse link
G YARS2 tyrosyl-tRNA synthetase 2 increases expression EXP Deoxyglucose results in increased expression of YARS2 mRNA CTD PMID:33770205 NCBI chr12:32,746,544...32,755,897
Ensembl chr12:32,727,490...32,755,897 		JBrowse link
G YES1 YES proto-oncogene 1, Src family tyrosine kinase decreases expression EXP Deoxyglucose results in decreased expression of YES1 mRNA CTD PMID:33770205 NCBI chr18:721,588...812,753
Ensembl chr18:721,588...812,546 		JBrowse link
G ZBTB1 zinc finger and BTB domain containing 1 increases expression EXP Deoxyglucose results in increased expression of ZBTB1 mRNA CTD PMID:33770205 NCBI chr14:64,503,716...64,533,693
Ensembl chr14:64,503,712...64,533,690 		JBrowse link
G ZFX zinc finger protein X-linked increases expression EXP Deoxyglucose results in increased expression of ZFX mRNA CTD PMID:33770205 NCBI chr  X:24,148,982...24,216,255
Ensembl chr  X:24,149,173...24,216,255 		JBrowse link
4-methylumbelliferyl beta-D-glucoside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GAA alpha glucosidase multiple interactions
increases metabolic processing		 EXP GAA gene SNP inhibits the reaction [GAA protein results in increased metabolism of 4-methylumbelliferyl glucoside] CTD PMID:21963784 NCBI chr17:80,101,581...80,119,881
Ensembl chr17:80,101,533...80,119,881 		JBrowse link
albiflorin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKT1 AKT serine/threonine kinase 1 multiple interactions EXP albiflorin inhibits the reaction [[Palmitic Acid co-treated with Glucose] results in increased phosphorylation of AKT1 protein] CTD PMID:37523837 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,759 		JBrowse link
G DRD2 dopamine receptor D2 affects expression ISO albiflorin affects the expression of DRD2 CTD PMID:26475043 NCBI chr11:113,409,605...113,475,398
Ensembl chr11:113,409,605...113,475,691 		JBrowse link
G EGFR epidermal growth factor receptor multiple interactions EXP albiflorin inhibits the reaction [[Palmitic Acid co-treated with Glucose] results in increased phosphorylation of EGFR protein] CTD PMID:37523837 NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628 		JBrowse link
G HTR1A 5-hydroxytryptamine receptor 1A affects expression ISO albiflorin affects the expression of HTR1A CTD PMID:26475043 NCBI chr 5:63,957,874...63,962,445
Ensembl chr 5:63,957,874...63,962,507 		JBrowse link
G HTR2A 5-hydroxytryptamine receptor 2A affects expression ISO albiflorin affects the expression of HTR2A CTD PMID:26475043 NCBI chr13:46,831,546...46,898,082
Ensembl chr13:46,831,546...46,897,076 		JBrowse link
G MAP3K7 mitogen-activated protein kinase kinase kinase 7 multiple interactions EXP Albiflorin inhibits the reaction [oxidized LDL increases phosphorylation of MAP3K7 protein in umbilical vein endothelial cells] RGD PMID:35601145 RGD:155804296 NCBI chr 6:90,513,579...90,587,072
Ensembl chr 6:90,513,573...90,587,086 		JBrowse link
G SLC6A3 solute carrier family 6 member 3 affects expression ISO albiflorin affects the expression of SLC6A3 CTD PMID:26475043 NCBI chr 5:1,392,794...1,445,440
Ensembl chr 5:1,392,794...1,445,440 		JBrowse link
G TH tyrosine hydroxylase affects expression ISO albiflorin affects the expression of TH CTD PMID:26475043 NCBI chr11:2,163,929...2,171,815
Ensembl chr11:2,163,929...2,171,815 		JBrowse link
alpha-D-glucose 1-phosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IDH2 isocitrate dehydrogenase (NADP(+)) 2 increases abundance
multiple interactions		 ISO IDH2 protein mutant form results in increased abundance of glucose-1-phosphate
Triazines inhibits the reaction [IDH2 protein mutant form results in increased abundance of glucose-1-phosphate]		 CTD PMID:27469509 NCBI chr15:90,083,045...90,102,468
Ensembl chr15:90,083,045...90,102,477 		JBrowse link
amikacin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCC3 ATP binding cassette subfamily C member 3 decreases expression ISO Amikacin results in decreased expression of ABCC3 mRNA CTD PMID:27765674 NCBI chr17:50,634,881...50,692,253
Ensembl chr17:50,634,777...50,692,253 		JBrowse link
G ABCC4 ATP binding cassette subfamily C member 4 (PEL blood group) decreases expression ISO Amikacin results in decreased expression of ABCC4 mRNA CTD PMID:27765674 NCBI chr13:95,019,835...95,301,451
Ensembl chr13:95,019,835...95,301,475 		JBrowse link
G CASR calcium sensing receptor increases activity EXP Amikacin results in increased activity of CASR protein CTD PMID:19884751 NCBI chr 3:122,183,668...122,291,629
Ensembl chr 3:122,183,668...122,291,629 		JBrowse link
G CAT catalase decreases activity
multiple interactions		 ISO
EXP		 Amikacin results in decreased activity of CAT protein
cefepime inhibits the reaction [Amikacin results in decreased activity of CAT protein]		 CTD PMID:18781908 PMID:23416261 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060 		JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 decreases expression EXP Amikacin results in decreased expression of CXCL8 mRNA CTD PMID:32816093 NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716 		JBrowse link
G IL1A interleukin 1 alpha decreases expression EXP Amikacin results in decreased expression of IL1A mRNA CTD PMID:32816093 NCBI chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493 		JBrowse link
G IL1B interleukin 1 beta decreases expression EXP Amikacin results in decreased expression of IL1B mRNA CTD PMID:32816093 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL24 interleukin 24 decreases expression EXP Amikacin results in decreased expression of IL24 mRNA CTD PMID:32816093 NCBI chr 1:206,897,443...206,904,139
Ensembl chr 1:206,897,443...206,904,139 		JBrowse link
G PGD phosphogluconate dehydrogenase decreases activity ISO Amikacin results in decreased activity of PGD protein CTD PMID:15558954 NCBI chr 1:10,399,064...10,420,511
Ensembl chr 1:10,398,592...10,420,511 		JBrowse link
G PID1 phosphotyrosine interaction domain containing 1 increases expression EXP Amikacin results in increased expression of PID1 mRNA CTD PMID:32816093 NCBI chr 2:229,023,973...229,271,287
Ensembl chr 2:228,850,526...229,271,287 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 decreases expression EXP Amikacin results in decreased expression of PTGS2 mRNA CTD PMID:32816093 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922 		JBrowse link
G SLC7A11 solute carrier family 7 member 11 decreases expression EXP Amikacin results in decreased expression of SLC7A11 mRNA CTD PMID:32816093 NCBI chr 4:138,164,097...138,312,671
Ensembl chr 4:138,164,097...138,242,349 		JBrowse link
G SLPI secretory leukocyte peptidase inhibitor increases expression EXP Amikacin results in increased expression of SLPI mRNA CTD PMID:32816093 NCBI chr20:45,252,239...45,254,564
Ensembl chr20:45,252,239...45,254,564 		JBrowse link
G SMN2 survival of motor neuron 2, centromeric increases expression EXP Amikacin results in increased expression of SMN2 protein CTD PMID:19150990 NCBI chr 5:70,049,523...70,090,528
Ensembl chr 5:70,049,638...70,078,522
Ensembl chr 5:70,049,638...70,078,522 		JBrowse link
G TYR tyrosinase decreases activity EXP Amikacin results in decreased activity of TYR protein CTD PMID:23416261 NCBI chr11:89,177,875...89,295,759
Ensembl chr11:89,177,875...89,295,759 		JBrowse link
apigenin 7-O-beta-D-glucoside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GYPA glycophorin A (MNS blood group) increases expression EXP apigetrin results in increased expression of GYPA protein CTD PMID:25058688 NCBI chr 4:144,109,303...144,140,718
Ensembl chr 4:144,109,303...144,140,751 		JBrowse link
asperuloside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HMOX1 heme oxygenase 1 multiple interactions ISO [lipopolysaccharide, E coli O55-B5 co-treated with asperuloside] results in increased expression of HMOX1 protein; asperuloside inhibits the reaction [Dextran Sulfate results in decreased expression of HMOX1 protein] CTD PMID:33974900 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214 		JBrowse link
G IL10 interleukin 10 multiple interactions ISO asperuloside inhibits the reaction [Dextran Sulfate results in decreased expression of IL10 protein] CTD PMID:33974900 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541 		JBrowse link
G IL6 interleukin 6 multiple interactions ISO asperuloside inhibits the reaction [Dextran Sulfate results in increased expression of IL6 protein]; asperuloside inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL6 mRNA]; asperuloside inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL6 protein] CTD PMID:33974900 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G MPO myeloperoxidase multiple interactions ISO asperuloside inhibits the reaction [Dextran Sulfate results in increased activity of MPO protein] CTD PMID:33974900 NCBI chr17:58,269,855...58,280,935
Ensembl chr17:58,269,855...58,280,935 		JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 multiple interactions
affects localization		 ISO [asperuloside co-treated with Dextran Sulfate] results in increased expression of NFE2L2 protein; [lipopolysaccharide, E coli O55-B5 co-treated with asperuloside] results in increased expression of NFE2L2 protein; asperuloside affects the reaction [NFE2L2 protein affects the expression of NQO1 mRNA]; asperuloside inhibits the reaction [lipopolysaccharide, E coli O55-B5 affects the localization of NFE2L2 protein]
asperuloside affects the localization of NFE2L2 protein		 CTD PMID:33974900 NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756 		JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 multiple interactions ISO asperuloside affects the reaction [NFE2L2 protein affects the expression of NQO1 mRNA] CTD PMID:33974900 NCBI chr16:69,709,401...69,726,560
Ensembl chr16:69,706,996...69,726,668 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit multiple interactions ISO asperuloside inhibits the reaction [Dextran Sulfate results in increased phosphorylation of RELA protein] CTD PMID:33974900 NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090 		JBrowse link
G TNF tumor necrosis factor multiple interactions ISO asperuloside inhibits the reaction [Dextran Sulfate results in increased expression of TNF protein]; asperuloside inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of TNF mRNA]; asperuloside inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of TNF protein]; asperuloside inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein] CTD PMID:16508180 PMID:33974900 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
beta-D-Gal-(1->3)-beta-D-GalNAc-(1->4)-[alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)]-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NOS2 nitric oxide synthase 2 multiple interactions ISO ganglioside, GD1b analog inhibits the reaction [[lipopolysaccharide, E. coli O26-B6 results in increased activity of NOS2 protein] which results in increased secretion of Nitrites]; ganglioside, GD1b inhibits the reaction [[lipopolysaccharide, E. coli O26-B6 results in increased activity of NOS2 protein] which results in increased secretion of Nitrites] CTD PMID:31202640 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529 		JBrowse link
beta-D-glucosamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AACS acetoacetyl-CoA synthetase increases expression ISO Glucosamine results in increased expression of AACS mRNA CTD PMID:17178593 NCBI chr12:125,065,435...125,143,316
Ensembl chr12:125,065,434...125,143,333 		JBrowse link
G ABCG1 ATP binding cassette subfamily G member 1 increases expression ISO Glucosamine results in increased expression of ABCG1 mRNA CTD PMID:17109745 NCBI chr21:42,199,689...42,297,244
Ensembl chr21:42,199,689...42,297,244 		JBrowse link
G ACACA acetyl-CoA carboxylase alpha increases expression EXP Glucosamine results in increased expression of ACACA mRNA CTD PMID:22096489 NCBI chr17:37,084,992...37,406,836
Ensembl chr17:37,084,992...37,406,836 		JBrowse link
G ACAN aggrecan multiple interactions
increases expression
decreases expression
affects expression		 EXP
ISO		 Glucosamine analog affects the reaction [IL1B results in decreased expression of ACAN mRNA]; Glucosamine inhibits the reaction [IL1B protein results in decreased expression of ACAN mRNA]; Glucosamine results in decreased cleavage of and results in decreased secretion of ACAN protein
Glucosamine results in increased expression of ACAN mRNA
Glucosamine inhibits the reaction [IL1B results in decreased expression of ACAN mRNA]
Glucosamine analog results in increased expression of ACAN protein; Glucosamine results in increased expression of ACAN mRNA; Glucosamine results in increased expression of ACAN protein
Glucosamine analog results in decreased expression of ACAN mRNA
Glucosamine analog affects the expression of ACAN mRNA		 CTD PMID:12801482 PMID:16300972 PMID:16872674 PMID:17109745 PMID:17337215 More... NCBI chr15:88,803,436...88,875,353
Ensembl chr15:88,803,436...88,875,353 		JBrowse link
G ACOT1 acyl-CoA thioesterase 1 increases expression ISO Glucosamine results in increased expression of ACOT1 mRNA CTD PMID:17178593 NCBI chr14:73,490,933...73,543,796
Ensembl chr14:73,537,143...73,543,796 		JBrowse link
G ACOX2 acyl-CoA oxidase 2 decreases expression ISO Glucosamine results in decreased expression of ACOX2 mRNA CTD PMID:17178593 NCBI chr 3:58,505,136...58,537,190
Ensembl chr 3:58,505,136...58,537,283 		JBrowse link
G ACSS2 acyl-CoA synthetase short chain family member 2 increases expression ISO Glucosamine results in increased expression of ACSS2 mRNA CTD PMID:17178593 NCBI chr20:34,874,989...34,927,959
Ensembl chr20:34,872,146...34,927,962 		JBrowse link
G ADAM15 ADAM metallopeptidase domain 15 multiple interactions
decreases expression		 ISO Glucosamine affects the reaction [IL1B results in decreased expression of ADAM15 mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of ADAM15 mRNA] CTD PMID:17109745 NCBI chr 1:155,051,316...155,062,775
Ensembl chr 1:155,050,566...155,062,775 		JBrowse link
G ADAM17 ADAM metallopeptidase domain 17 multiple interactions
increases expression		 ISO Glucosamine inhibits the reaction [IL1B results in increased expression of ADAM17 mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of ADAM17 mRNA] CTD PMID:17109745 NCBI chr 2:9,488,486...9,555,830
Ensembl chr 2:9,488,486...9,556,732 		JBrowse link
G ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif 1 decreases expression
multiple interactions		 EXP
ISO		 Glucosamine analog results in decreased expression of ADAMTS1 mRNA
Glucosamine results in decreased expression of ADAMTS1 mRNA
Glucosamine inhibits the reaction [IL1B results in increased expression of ADAMTS1 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of ADAMTS1 mRNA]		 CTD PMID:16300972 PMID:17109745 NCBI chr21:26,835,755...26,845,409
Ensembl chr21:26,835,755...26,845,409 		JBrowse link
G ADAMTS20 ADAM metallopeptidase with thrombospondin type 1 motif 20 decreases cleavage EXP Glucosamine results in decreased cleavage of ADAMTS20 protein alternative form CTD PMID:19909832 NCBI chr12:43,352,763...43,552,203
Ensembl chr12:43,353,866...43,552,203 		JBrowse link
G ADAMTS4 ADAM metallopeptidase with thrombospondin type 1 motif 4 increases expression ISO Glucosamine results in increased expression of ADAMTS4 mRNA CTD PMID:17109745 NCBI chr 1:161,184,302...161,199,054
Ensembl chr 1:161,184,302...161,199,054 		JBrowse link
G ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif 5 decreases expression
multiple interactions		 EXP Glucosamine analog results in decreased expression of ADAMTS5 mRNA
Glucosamine results in decreased cleavage of and results in decreased activity of ADAMTS5 protein alternative form		 CTD PMID:16300972 PMID:19909832 NCBI chr21:26,917,922...26,967,088
Ensembl chr21:26,917,922...26,967,088 		JBrowse link
G ADAMTS9 ADAM metallopeptidase with thrombospondin type 1 motif 9 decreases cleavage EXP Glucosamine results in decreased cleavage of ADAMTS9 protein alternative form CTD PMID:19909832 NCBI chr 3:64,515,654...64,688,000
Ensembl chr 3:64,515,654...64,688,000 		JBrowse link
G ADIPOQ adiponectin, C1Q and collagen domain containing increases expression ISO Glucosamine results in increased expression of ADIPOQ mRNA CTD PMID:15694357 NCBI chr 3:186,842,710...186,858,463
Ensembl chr 3:186,842,704...186,858,463 		JBrowse link
G AFP alpha fetoprotein increases expression ISO Glucosamine results in increased expression of AFP mRNA CTD PMID:17178593 NCBI chr 4:73,436,221...73,456,174
Ensembl chr 4:73,431,138...73,456,174 		JBrowse link
G AGT angiotensinogen increases expression ISO Glucosamine results in increased expression of AGT mRNA CTD PMID:17178593 NCBI chr 1:230,702,523...230,745,583
Ensembl chr 1:230,690,776...230,745,576 		JBrowse link
G AHI1 Abelson helper integration site 1 decreases expression ISO Glucosamine results in decreased expression of AHI1 mRNA CTD PMID:17178593 NCBI chr 6:135,283,532...135,497,740
Ensembl chr 6:135,283,407...135,498,434 		JBrowse link
G AKT1 AKT serine/threonine kinase 1 affects phosphorylation
multiple interactions		 EXP
ISO		 Glucosamine analog affects the phosphorylation of AKT1 protein
Glucosamine inhibits the reaction [INS1 protein results in increased phosphorylation of AKT1 protein]; OSTN protein affects the reaction [Glucosamine inhibits the reaction [INS1 protein results in increased phosphorylation of AKT1 protein]]
Glucosamine analog affects the reaction [IL1B results in increased phosphorylation of AKT1 protein]; Glucosamine promotes the reaction [IL1B results in increased phosphorylation of AKT1 protein]		 CTD PMID:18080321 PMID:18340449 PMID:30602124 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,759 		JBrowse link
G ALB albumin multiple interactions ISO [LEPR protein affects the susceptibility to Glucosamine] which affects the expression of ALB protein CTD PMID:33345901 NCBI chr 4:73,404,287...73,421,482
Ensembl chr 4:73,397,114...73,421,482 		JBrowse link
G ALG12 ALG12 alpha-1,6-mannosyltransferase decreases expression ISO Glucosamine results in decreased expression of ALG12 mRNA CTD PMID:17178593 NCBI chr22:49,859,311...49,918,438
Ensembl chr22:49,900,229...49,918,438 		JBrowse link
G ALPL alkaline phosphatase, biomineralization associated multiple interactions
increases expression
increases activity		 EXP 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [Glucosamine analog results in increased activity of ALPL protein]
Glucosamine analog results in increased expression of ALPL mRNA		 CTD PMID:20458730 NCBI chr 1:21,508,984...21,578,410
Ensembl chr 1:21,509,397...21,578,410 		JBrowse link
G APOA1 apolipoprotein A1 increases secretion
increases stability		 EXP Glucosamine results in increased secretion of APOA1 protein
Glucosamine results in increased stability of APOA1 mRNA		 CTD PMID:15164326 NCBI chr11:116,835,751...116,837,950
Ensembl chr11:116,835,751...116,837,622 		JBrowse link
G APOB apolipoprotein B multiple interactions
increases degradation
increases ubiquitination
decreases secretion
decreases localization
decreases expression		 EXP
ISO		 acetylleucyl-leucyl-norleucinal inhibits the reaction [Glucosamine results in decreased expression of and results in decreased secretion of APOB protein]; Glucosamine results in decreased expression of and results in decreased secretion of APOB protein; Oleic Acid inhibits the reaction [Glucosamine results in decreased secretion of APOB protein]
Oleic Acid inhibits the reaction [Glucosamine results in increased degradation of APOB protein]
Glucosamine results in increased ubiquitination of APOB protein
Glucosamine results in decreased localization of APOB protein
Glucosamine results in decreased expression of APOB protein		 CTD PMID:15618547 PMID:19383982 NCBI chr 2:21,001,429...21,044,073
Ensembl chr 2:21,001,429...21,044,073 		JBrowse link
G APOE apolipoprotein E multiple interactions ISO [Streptozocin co-treated with APOE mutant form] results in increased abundance of Glucosamine; INS1 inhibits the reaction [[Streptozocin co-treated with APOE mutant form] results in increased abundance of Glucosamine] CTD PMID:16380481 NCBI chr19:44,905,796...44,909,393
Ensembl chr19:44,905,791...44,909,393 		JBrowse link
G ASS1 argininosuccinate synthase 1 multiple interactions ISO Glucosamine inhibits the reaction [IL1B results in increased expression of ASS1 mRNA] CTD PMID:17109745 NCBI chr 9:130,444,707...130,501,274
Ensembl chr 9:130,444,961...130,501,274 		JBrowse link
G ATF3 activating transcription factor 3 decreases expression ISO Glucosamine results in decreased expression of ATF3 mRNA CTD PMID:17178593 NCBI chr 1:212,565,407...212,620,777
Ensembl chr 1:212,565,334...212,620,777 		JBrowse link
G ATF4 activating transcription factor 4 multiple interactions
increases expression		 ISO
EXP		 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of ATF4 mRNA]; 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of ATF4 protein]; EIF2AK3 protein affects the reaction [Glucosamine results in increased expression of ATF4 mRNA]; GSK2656157 inhibits the reaction [Glucosamine results in increased expression of ATF4 mRNA]
NUS1 protein inhibits the reaction [Glucosamine results in increased expression of ATF4 mRNA]
Glucosamine results in increased expression of ATF4 mRNA; Glucosamine results in increased expression of ATF4 protein		 CTD PMID:30602124 PMID:33812996 NCBI chr22:39,520,559...39,522,686
Ensembl chr22:39,519,695...39,522,683 		JBrowse link
G ATF6 activating transcription factor 6 multiple interactions
increases expression
decreases expression		 EXP
ISO		 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of ATF6 mRNA]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of MEF2A mRNA]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of MEF2A protein]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of PPARGC1A mRNA]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of PPARGC1A protein]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of SLC2A4 mRNA]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of SLC2A4 protein]; NUS1 protein inhibits the reaction [Glucosamine results in increased expression of ATF6 mRNA]; ursodoxicoltaurine inhibits the reaction [Glucosamine results in increased expression of ATF6 mRNA]
ATF6 protein affects the reaction [Glucosamine results in increased expression of OSTN mRNA]
Glucosamine results in increased expression of ATF6 protein
4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of ATF6 mRNA]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of MEF2A mRNA]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of MEF2A protein]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of PPARGC1A mRNA]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of PPARGC1A protein]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of SLC2A4 mRNA]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of SLC2A4 protein]; ursodoxicoltaurine inhibits the reaction [Glucosamine results in increased expression of ATF6 mRNA]
Glucosamine results in decreased expression of ATF6 mRNA		 CTD PMID:17178593 PMID:19383982 PMID:20165829 PMID:30602124 PMID:33812996 NCBI chr 1:161,766,320...161,964,070
Ensembl chr 1:161,766,298...161,977,574 		JBrowse link
G ATF7IP activating transcription factor 7 interacting protein increases expression ISO Glucosamine results in increased expression of ATF7IP mRNA CTD PMID:17178593 NCBI chr12:14,365,682...14,502,930
Ensembl chr12:14,365,676...14,502,931 		JBrowse link
G ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 decreases expression ISO Glucosamine results in decreased expression of ATP2A2 mRNA CTD PMID:17178593 NCBI chr12:110,280,616...110,351,093
Ensembl chr12:110,280,756...110,351,093 		JBrowse link
G AZIN1 antizyme inhibitor 1 decreases expression
multiple interactions		 ISO Glucosamine results in decreased expression of AZIN1 mRNA
IL1B promotes the reaction [Glucosamine results in increased expression of AZIN1 mRNA]		 CTD PMID:17109745 NCBI chr 8:102,826,302...102,864,200
Ensembl chr 8:102,826,111...102,893,864 		JBrowse link
G B3GAT3 beta-1,3-glucuronyltransferase 3 multiple interactions
increases expression		 ISO [XDH protein co-treated with Hypoxanthine] inhibits the reaction [Glucosamine results in increased expression of B3GAT3 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in decreased activity of B3GAT3 protein]; Glucosamine inhibits the reaction [IL1B protein results in decreased expression of B3GAT3 mRNA] CTD PMID:11229466 PMID:11801247 NCBI chr11:62,615,296...62,621,986
Ensembl chr11:62,615,296...62,622,154 		JBrowse link
G BCL2L1 BCL2 like 1 decreases expression
multiple interactions		 EXP Glucosamine results in decreased expression of BCL2L1 protein
pepstatin inhibits the reaction [Glucosamine results in decreased expression of BCL2L1 protein]		 CTD PMID:15972124 PMID:16850161 NCBI chr20:31,664,452...31,723,963
Ensembl chr20:31,664,452...31,723,989 		JBrowse link
G BDNF brain derived neurotrophic factor decreases expression ISO Glucosamine results in decreased expression of BDNF mRNA CTD PMID:17178593 NCBI chr11:27,654,893...27,722,030
Ensembl chr11:27,654,893...27,722,058 		JBrowse link
G BGLAP bone gamma-carboxyglutamate protein increases expression EXP Glucosamine analog results in increased expression of BGLAP mRNA CTD PMID:20458730 NCBI chr 1:156,242,184...156,243,317
Ensembl chr 1:156,242,184...156,243,317 		JBrowse link
G BGN biglycan multiple interactions
decreases expression		 ISO Glucosamine inhibits the reaction [IL1B results in increased expression of BGN mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of BGN mRNA] CTD PMID:17109745 NCBI chr  X:153,494,980...153,509,546
Ensembl chr  X:153,494,980...153,509,546 		JBrowse link
G BMAL1 basic helix-loop-helix ARNT like 1 decreases expression ISO Glucosamine results in decreased expression of BMAL1 mRNA; Glucosamine results in decreased expression of BMAL1 protein CTD PMID:24442997 NCBI chr11:13,276,652...13,387,266
Ensembl chr11:13,276,652...13,387,266 		JBrowse link
G BMP2 bone morphogenetic protein 2 multiple interactions ISO Glucosamine inhibits the reaction [IL1B results in increased expression of BMP2 mRNA] CTD PMID:17109745 NCBI chr20:6,767,686...6,780,246
Ensembl chr20:6,767,686...6,780,246 		JBrowse link
G BMP4 bone morphogenetic protein 4 decreases expression
multiple interactions		 ISO Glucosamine results in decreased expression of BMP4 mRNA
Glucosamine promotes the reaction [IL1B results in decreased expression of BMP4 mRNA]		 CTD PMID:17109745 NCBI chr14:53,949,736...53,956,891
Ensembl chr14:53,949,736...53,958,761 		JBrowse link
G BMP6 bone morphogenetic protein 6 multiple interactions
decreases expression		 ISO Glucosamine inhibits the reaction [IL1B results in increased expression of BMP6 mRNA]
Glucosamine results in decreased expression of BMP6 mRNA		 CTD PMID:17109745 NCBI chr 6:7,726,099...7,881,728
Ensembl chr 6:7,726,099...7,881,728 		JBrowse link
G BMP7 bone morphogenetic protein 7 multiple interactions
increases expression		 ISO Glucosamine inhibits the reaction [IL1B results in increased expression of BMP7 mRNA]
Glucosamine results in increased expression of BMP7 mRNA		 CTD PMID:17109745 NCBI chr20:57,168,753...57,266,641
Ensembl chr20:57,168,753...57,266,641 		JBrowse link
G CA3 carbonic anhydrase 3 decreases expression ISO Glucosamine results in decreased expression of CAR3 mRNA CTD PMID:17109745 NCBI chr 8:85,438,859...85,449,040
Ensembl chr 8:85,373,436...85,449,040 		JBrowse link
G CALR calreticulin decreases expression ISO Glucosamine results in decreased expression of CALR mRNA CTD PMID:17178593 NCBI chr19:12,938,609...12,944,489
Ensembl chr19:12,938,578...12,944,489 		JBrowse link
G CASP3 caspase 3 increases cleavage
multiple interactions		 EXP Glucosamine results in increased cleavage of CASP3 protein
Glucosamine results in increased activity of and results in increased cleavage of CASP3 protein		 CTD PMID:16850161 PMID:22020377 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062 		JBrowse link
G CASP4 caspase 4 decreases expression ISO Glucosamine results in decreased expression of CASP4 mRNA CTD PMID:17178593 NCBI chr11:104,942,866...104,968,574
Ensembl chr11:104,942,866...104,969,366 		JBrowse link
G CBR3 carbonyl reductase 3 increases expression ISO Glucosamine results in increased expression of CBR3 mRNA CTD PMID:17178593 NCBI chr21:36,135,079...36,146,562
Ensembl chr21:36,135,079...36,146,562 		JBrowse link
G CCL2 C-C motif chemokine ligand 2 multiple interactions
increases expression		 EXP
ISO		 Alloxan inhibits the reaction [Glucosamine inhibits the reaction [Cathelicidins results in increased expression of CCL2 protein]]; Glucosamine analog inhibits the reaction [IL1B results in increased secretion of CCL2 protein]; Glucosamine inhibits the reaction [Cathelicidins results in increased expression of CCL2 mRNA]; Glucosamine inhibits the reaction [Cathelicidins results in increased expression of CCL2 protein]; Glucosamine inhibits the reaction [TNF results in increased expression of CCL2 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of CCL2 protein]
Glucosamine results in increased expression of CCL2 mRNA
Glucosamine inhibits the reaction [IL1B results in increased expression of CCL2 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of CCL2 mRNA]		 CTD PMID:17109745 PMID:18080321 PMID:18949387 PMID:19020780 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208 		JBrowse link
G CCL20 C-C motif chemokine ligand 20 multiple interactions
increases expression		 ISO Glucosamine inhibits the reaction [IL1B results in increased expression of CCL20 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of CCL20 mRNA] CTD PMID:17109745 NCBI chr 2:227,813,842...227,817,556
Ensembl chr 2:227,805,739...227,817,564 		JBrowse link
G CCL22 C-C motif chemokine ligand 22 multiple interactions ISO Glucosamine inhibits the reaction [IL1B results in increased expression of CCL22 mRNA] CTD PMID:17109745 NCBI chr16:57,357,909...57,366,189
Ensembl chr16:57,358,783...57,366,189 		JBrowse link
G CCL3 C-C motif chemokine ligand 3 multiple interactions ISO Glucosamine inhibits the reaction [IL1B results in increased expression of CCL3 mRNA] CTD PMID:17109745 NCBI chr17:36,088,256...36,090,143
Ensembl chr17:36,088,256...36,090,169 		JBrowse link
G CCL5 C-C motif chemokine ligand 5 multiple interactions EXP
ISO		 Glucosamine analog inhibits the reaction [IL1B results in increased secretion of CCL5 protein]
Glucosamine inhibits the reaction [IL1B results in increased expression of CCL5 mRNA]		 CTD PMID:17109745 PMID:18080321 NCBI chr17:35,871,491...35,880,360
Ensembl chr17:35,871,491...35,880,793 		JBrowse link
G CCL7 C-C motif chemokine ligand 7 multiple interactions
increases expression		 ISO Glucosamine inhibits the reaction [IL1B results in increased expression of CCL7 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of CCL7 mRNA] CTD PMID:17109745 NCBI chr17:34,270,221...34,272,242
Ensembl chr17:34,270,221...34,272,242 		JBrowse link
G CCN2 cellular communication network factor 2 increases expression ISO Glucosamine analog results in increased expression of CCN2 mRNA CTD PMID:21466783 NCBI chr 6:131,948,176...131,951,372
Ensembl chr 6:131,948,176...131,951,372 		JBrowse link
G CCNB1 cyclin B1 decreases expression ISO Glucosamine results in decreased expression of CCNB1 mRNA CTD PMID:17109745 NCBI chr 5:69,167,150...69,178,245
Ensembl chr 5:69,167,135...69,178,245 		JBrowse link
G CD24 CD24 molecule increases expression ISO Glucosamine results in increased expression of CD24A mRNA CTD PMID:17178593 NCBI chr 6:106,969,831...106,976,855
Ensembl chr 6:106,969,831...106,975,627 		JBrowse link
G CD28 CD28 molecule increases expression ISO Glucosamine results in increased expression of CD28 mRNA CTD PMID:17109745 NCBI chr 2:203,706,482...203,738,912
Ensembl chr 2:203,706,475...203,738,912 		JBrowse link
G CDC20 cell division cycle 20 decreases expression ISO Glucosamine results in decreased expression of CDC20 mRNA CTD PMID:17109745 NCBI chr 1:43,358,981...43,363,203
Ensembl chr 1:43,358,981...43,363,203 		JBrowse link
G CDC23 cell division cycle 23 decreases expression ISO Glucosamine results in decreased expression of CDC23 mRNA CTD PMID:17109745 NCBI chr 5:138,187,650...138,213,323
Ensembl chr 5:138,187,650...138,213,343 		JBrowse link
G CDK1 cyclin dependent kinase 1 decreases expression ISO Glucosamine results in decreased expression of CDK1 mRNA CTD PMID:17109745 NCBI chr10:60,778,331...60,794,852
Ensembl chr10:60,778,331...60,794,852 		JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A increases expression ISO Glucosamine results in increased expression of CDKN1A protein
Glucosamine results in increased expression of CDKN1A mRNA		 CTD PMID:15654767 PMID:17178593 NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,337 		JBrowse link
G CDKN1B cyclin dependent kinase inhibitor 1B decreases expression ISO Glucosamine results in decreased expression of CDKN1B protein CTD PMID:15654767 NCBI chr12:12,717,368...12,722,369
Ensembl chr12:12,685,498...12,722,369 		JBrowse link
G CDKN3 cyclin dependent kinase inhibitor 3 decreases expression ISO Glucosamine results in decreased expression of CDKN3 mRNA CTD PMID:17109745 NCBI chr14:54,397,007...54,420,218
Ensembl chr14:54,396,849...54,420,218 		JBrowse link
G CENPF centromere protein F decreases expression ISO Glucosamine results in decreased expression of CENPF mRNA CTD PMID:17109745 NCBI chr 1:214,603,195...214,664,571
Ensembl chr 1:214,603,185...214,664,574 		JBrowse link
G CHI3L1 chitinase 3 like 1 decreases expression EXP Glucosamine analog results in decreased expression of CHI3L1 mRNA CTD PMID:16142878 NCBI chr 1:203,178,931...203,186,704
Ensembl chr 1:203,178,931...203,186,704 		JBrowse link
G CHUK component of inhibitor of nuclear factor kappa B kinase complex multiple interactions
decreases activity		 EXP Glucosamine analog results in decreased activity of and results in decreased localization of CHUK protein
Glucosamine analog results in decreased activity of CHUK protein		 CTD PMID:20113495 NCBI chr10:100,186,319...100,229,596
Ensembl chr10:100,188,300...100,229,596 		JBrowse link
G CKAP2 cytoskeleton associated protein 2 decreases expression ISO Glucosamine results in decreased expression of CKAP2 mRNA CTD PMID:17109745 NCBI chr13:52,455,478...52,476,627
Ensembl chr13:52,455,429...52,476,628 		JBrowse link
G CLOCK clock circadian regulator decreases expression ISO Glucosamine results in decreased expression of CLOCK mRNA; Glucosamine results in decreased expression of CLOCK protein CTD PMID:24442997 NCBI chr 4:55,427,903...55,546,909
Ensembl chr 4:55,427,903...55,546,909 		JBrowse link
G CLTA clathrin light chain A decreases expression ISO Glucosamine results in decreased expression of CLTA mRNA CTD PMID:17109745 NCBI chr 9:36,190,874...36,212,059
Ensembl chr 9:36,190,856...36,304,781 		JBrowse link
G COL11A1 collagen type XI alpha 1 chain multiple interactions
decreases expression		 ISO Glucosamine inhibits the reaction [IL1B results in decreased expression of COL11A1 mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of COL11A1 mRNA] CTD PMID:17109745 NCBI chr 1:102,876,473...103,108,522
Ensembl chr 1:102,876,467...103,108,872 		JBrowse link
G COL1A1 collagen type I alpha 1 chain multiple interactions
decreases expression		 EXP Glucosamine inhibits the reaction [IL1B protein results in increased expression of COL1A1 mRNA]
Glucosamine results in decreased expression of COL1A1 mRNA		 CTD PMID:18321735 NCBI chr17:50,184,101...50,201,631
Ensembl chr17:50,184,101...50,201,632 		JBrowse link
G COL2A1 collagen type II alpha 1 chain multiple interactions
affects expression
increases expression		 EXP
ISO		 Glucosamine analog affects the reaction [IL1B results in decreased expression of COL2A1 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in decreased expression of COL2A1 mRNA]
Glucosamine inhibits the reaction [IL1B results in decreased expression of COL2A1 mRNA]
Glucosamine analog affects the expression of COL2A1 mRNA
Glucosamine analog results in increased expression of COL2A1 mRNA; Glucosamine results in increased expression of COL2A1 mRNA		 CTD PMID:16300972 PMID:17109745 PMID:17337215 PMID:18321735 NCBI chr12:47,972,967...48,006,212
Ensembl chr12:47,972,967...48,004,554 		JBrowse link
G COL3A1 collagen type III alpha 1 chain multiple interactions ISO Glucosamine inhibits the reaction [IL1B results in decreased expression of COL3A1 mRNA] CTD PMID:17109745 NCBI chr 2:188,974,373...189,012,746
Ensembl chr 2:188,974,373...189,012,746 		JBrowse link
G COL8A1 collagen type VIII alpha 1 chain multiple interactions
decreases expression		 ISO Glucosamine inhibits the reaction [IL1B results in increased expression of COL8A1 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of COL8A1 mRNA] CTD PMID:17109745 NCBI chr 3:99,638,594...99,799,217
Ensembl chr 3:99,638,475...99,799,226 		JBrowse link
G CSF1 colony stimulating factor 1 multiple interactions
decreases expression		 ISO Glucosamine inhibits the reaction [IL1B results in increased expression of CSF1 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of CSF1 mRNA] CTD PMID:17109745 NCBI chr 1:109,910,506...109,930,992
Ensembl chr 1:109,910,242...109,930,992 		JBrowse link
G CSF2 colony stimulating factor 2 multiple interactions
increases expression		 ISO Glucosamine inhibits the reaction [IL1B results in increased expression of CSF2 mRNA]
Glucosamine results in increased expression of CSF2 mRNA		 CTD PMID:17109745 NCBI chr 5:132,073,789...132,076,170
Ensembl chr 5:132,073,789...132,076,170 		JBrowse link
G CSF3 colony stimulating factor 3 multiple interactions
increases expression		 ISO Glucosamine inhibits the reaction [IL1B results in increased expression of CSF3 mRNA]
Glucosamine results in increased expression of CSF3 mRNA		 CTD PMID:17109745 NCBI chr17:40,015,440...40,017,813
Ensembl chr17:40,015,361...40,017,813 		JBrowse link
G CTSD cathepsin D affects localization
multiple interactions
increases activity
decreases expression		 EXP Glucosamine affects the localization of CTSD protein
pepstatin inhibits the reaction [Glucosamine results in decreased expression of CTSD protein alternative form]
Glucosamine results in increased activity of CTSD protein		 CTD PMID:15972124 PMID:16850161 NCBI chr11:1,752,755...1,763,927
Ensembl chr11:1,752,752...1,764,573 		JBrowse link
G CUL2 cullin 2 multiple interactions EXP Glucosamine analog inhibits the reaction [TNF results in increased expression of CUL2 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of CUL2 mRNA] CTD PMID:18173918 NCBI chr10:35,008,551...35,127,006
Ensembl chr10:35,008,504...35,127,006 		JBrowse link
G CXCL1 C-X-C motif chemokine ligand 1 multiple interactions
increases expression
decreases expression		 ISO Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL1 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of CXCL1 mRNA]
Glucosamine results in increased expression of CXCL3 mRNA
Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL3 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of CXCL3 mRNA]		 CTD PMID:17109745 NCBI chr 4:73,869,393...73,871,308
Ensembl chr 4:73,869,393...73,871,308 		JBrowse link
G CXCL10 C-X-C motif chemokine ligand 10 multiple interactions ISO Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL10 mRNA]
Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL10 mRNA]		 CTD PMID:17109745 PMID:20737476 NCBI chr 4:76,021,118...76,023,497
Ensembl chr 4:76,021,118...76,023,497 		JBrowse link
G CXCL11 C-X-C motif chemokine ligand 11 multiple interactions ISO Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL11 mRNA] CTD PMID:17109745 NCBI chr 4:76,033,682...76,036,070
Ensembl chr 4:76,033,682...76,041,415 		JBrowse link
G CXCL12 C-X-C motif chemokine ligand 12 multiple interactions
decreases expression		 ISO Glucosamine promotes the reaction [IL1B results in decreased expression of CXCL12 mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of CXCL12 mRNA] CTD PMID:17109745 NCBI chr10:44,370,165...44,385,097
Ensembl chr10:44,370,165...44,386,493 		JBrowse link
G CXCL2 C-X-C motif chemokine ligand 2 multiple interactions
increases expression		 ISO Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL2 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of CXCL2 mRNA] CTD PMID:17109745 NCBI chr 4:74,097,040...74,099,195
Ensembl chr 4:74,097,040...74,099,196 		JBrowse link
G CXCL6 C-X-C motif chemokine ligand 6 multiple interactions ISO Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL5 mRNA] CTD PMID:17109745 NCBI chr 4:73,836,678...73,838,760
Ensembl chr 4:73,836,640...73,849,064 		JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 multiple interactions EXP Glucosamine analog inhibits the reaction [IL1B results in increased expression of CXCL8 mRNA]; Glucosamine analog inhibits the reaction [IL1B results in increased secretion of CXCL8 protein]; Glucosamine analog inhibits the reaction [TNF results in increased expression of CXCL8 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL8 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL8 protein]; Glucosamine inhibits the reaction [IL1B results in increased secretion of CXCL8 protein]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased secretion of CXCL8 protein]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL8 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of CXCL8 mRNA] CTD PMID:18026701 PMID:18080321 PMID:19626664 PMID:20113495 PMID:20307528 NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716 		JBrowse link
G CYBA cytochrome b-245 alpha chain decreases expression EXP Glucosamine results in decreased expression of CYBA mRNA CTD PMID:18077487 NCBI chr16:88,643,289...88,651,053
Ensembl chr16:88,643,275...88,651,083 		JBrowse link
G CYCS cytochrome c, somatic affects localization EXP Glucosamine affects the localization of CYCS protein CTD PMID:15972124 PMID:22020377 NCBI chr 7:25,118,656...25,125,260
Ensembl chr 7:25,118,656...25,125,260 		JBrowse link
G CYP51A1 cytochrome P450 family 51 subfamily A member 1 increases expression ISO Glucosamine results in increased expression of CYP51 mRNA CTD PMID:17178593 NCBI chr 7:92,112,153...92,134,803
Ensembl chr 7:92,084,987...92,134,803 		JBrowse link
G DBI diazepam binding inhibitor, acyl-CoA binding protein increases expression ISO Glucosamine results in increased expression of DBI mRNA CTD PMID:17178593 NCBI chr 2:119,366,977...119,372,543
Ensembl chr 2:119,366,924...119,372,550 		JBrowse link
G DDIT3 DNA damage inducible transcript 3 increases expression
multiple interactions
decreases expression		 EXP
ISO		 Glucosamine results in increased expression of DDIT3 mRNA; Glucosamine results in increased expression of DDIT3 protein
NUS1 protein inhibits the reaction [Glucosamine results in increased expression of DDIT3 mRNA]
4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of DDIT3 mRNA]; 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of DDIT3 protein]
Glucosamine results in decreased expression of DDIT3 mRNA		 CTD PMID:16380481 PMID:17178593 PMID:30602124 PMID:33812996 NCBI chr12:57,516,588...57,520,517
Ensembl chr12:57,516,588...57,521,737 		JBrowse link
G DDIT4L DNA damage inducible transcript 4 like increases expression ISO Glucosamine results in increased expression of DDIT4L mRNA CTD PMID:17109745 NCBI chr 4:100,185,870...100,190,468
Ensembl chr 4:100,185,870...100,190,782 		JBrowse link
G DHCR7 7-dehydrocholesterol reductase increases expression ISO Glucosamine results in increased expression of DHCR7 mRNA CTD PMID:17178593 NCBI chr11:71,434,411...71,448,393
Ensembl chr11:71,428,193...71,452,868 		JBrowse link
G DNAJB11 DnaJ heat shock protein family (Hsp40) member B11 decreases expression ISO Glucosamine results in decreased expression of DNAJB11 mRNA CTD PMID:17178593 NCBI chr 3:186,570,720...186,585,793
Ensembl chr 3:186,567,403...186,585,800 		JBrowse link
G DNAJB9 DnaJ heat shock protein family (Hsp40) member B9 decreases expression ISO Glucosamine results in decreased expression of DNAJB9 mRNA CTD PMID:17178593 NCBI chr 7:108,569,874...108,574,850
Ensembl chr 7:108,569,867...108,574,850 		JBrowse link
G DNAJC3 DnaJ heat shock protein family (Hsp40) member C3 decreases expression ISO Glucosamine results in decreased expression of DNAJC3 mRNA CTD PMID:17178593 NCBI chr13:95,677,139...95,794,988
Ensembl chr13:95,677,139...95,794,988 		JBrowse link
G DSPP dentin sialophosphoprotein decreases expression EXP Glucosamine analog results in decreased expression of DSPP mRNA CTD PMID:20458730 NCBI chr 4:87,608,529...87,616,873
Ensembl chr 4:87,608,529...87,616,873 		JBrowse link
G DUSP5 dual specificity phosphatase 5 multiple interactions
increases expression		 ISO Glucosamine inhibits the reaction [IL1B results in increased expression of DUSP5 mRNA]
Glucosamine results in increased expression of DUSP5 mRNA		 CTD PMID:17109745 NCBI chr10:110,497,907...110,511,533
Ensembl chr10:110,497,907...110,511,533 		JBrowse link
G DUSP7 dual specificity phosphatase 7 multiple interactions
decreases expression		 ISO Glucosamine inhibits the reaction [IL1B results in increased expression of DUSP7 mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of DUSP7 mRNA] CTD PMID:17109745 NCBI chr 3:52,048,919...52,056,571
Ensembl chr 3:52,048,919...52,056,571 		JBrowse link
G DYNC1I1 dynein cytoplasmic 1 intermediate chain 1 decreases expression ISO Glucosamine results in decreased expression of DYNC1I1 mRNA CTD PMID:17109745 NCBI chr 7:95,772,554...96,110,322
Ensembl chr 7:95,772,506...96,110,322 		JBrowse link
G EDEM1 ER degradation enhancing alpha-mannosidase like protein 1 decreases expression ISO Glucosamine results in decreased expression of EDEM1 mRNA CTD PMID:17178593 NCBI chr 3:5,187,707...5,219,958
Ensembl chr 3:5,187,646...5,219,958 		JBrowse link
G EIF2AK3 eukaryotic translation initiation factor 2 alpha kinase 3 multiple interactions
increases expression
increases phosphorylation		 ISO
EXP		 EIF2AK3 gene mutant form inhibits the reaction [Glucosamine results in increased phosphorylation of EIF2S1 protein]
NUS1 protein inhibits the reaction [Glucosamine results in increased expression of EIF2AK3 protein]
EIF2AK3 protein affects the reaction [Glucosamine results in increased expression of ATF4 mRNA]; EIF2AK3 protein affects the reaction [Glucosamine results in increased expression of OSTN mRNA]; EIF2AK3 protein affects the reaction [Glucosamine results in increased phosphorylation of EIF2S1 protein]
Glucosamine results in increased phosphorylation of EIF2AK3 protein		 CTD PMID:16324875 PMID:19383982 PMID:30602124 PMID:33812996 NCBI chr 2:88,556,741...88,628,145
Ensembl chr 2:88,556,741...88,691,518 		JBrowse link
G EIF2S1 eukaryotic translation initiation factor 2 subunit alpha increases phosphorylation
multiple interactions		 EXP
ISO		 Glucosamine results in increased phosphorylation of EIF2S1 protein
NUS1 protein inhibits the reaction [Glucosamine results in increased phosphorylation of EIF2S1 protein]
4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased phosphorylation of EIF2S1 protein]; EIF2AK3 protein affects the reaction [Glucosamine results in increased phosphorylation of EIF2S1 protein]; GSK2656157 inhibits the reaction [Glucosamine results in increased phosphorylation of EIF2S1 protein]
EIF2AK3 gene mutant form inhibits the reaction [Glucosamine results in increased phosphorylation of EIF2S1 protein]		 CTD PMID:16324875 PMID:19383982 PMID:30602124 PMID:33812996 NCBI chr14:67,360,328...67,386,516
Ensembl chr14:67,360,328...67,386,516 		JBrowse link
G ELOVL6 ELOVL fatty acid elongase 6 increases expression ISO Glucosamine results in increased expression of ELOVL6 mRNA CTD PMID:17178593 NCBI chr 4:110,045,846...110,199,202
Ensembl chr 4:110,045,846...110,199,199 		JBrowse link
G EPAS1 endothelial PAS domain protein 1 decreases expression
multiple interactions		 ISO Glucosamine results in decreased expression of EPAS1 mRNA
Glucosamine inhibits the reaction [IL1B results in increased expression of EPAS1 mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of EPAS1 mRNA]		 CTD PMID:17109745 NCBI chr 2:46,297,407...46,386,697
Ensembl chr 2:46,293,667...46,386,697 		JBrowse link
G EPRS1 glutamyl-prolyl-tRNA synthetase 1 decreases expression ISO Glucosamine results in decreased expression of EPRS1 mRNA CTD PMID:17178593 NCBI chr 1:219,968,600...220,046,505
Ensembl chr 1:219,968,600...220,046,530 		JBrowse link
G ERN1 endoplasmic reticulum to nucleus signaling 1 multiple interactions
increases expression		 ISO
EXP		 ERN1 protein affects the reaction [Glucosamine results in increased expression of OSTN mRNA]; ERN1 protein affects the reaction [Glucosamine results in increased splicing of XBP1 mRNA]
NUS1 protein inhibits the reaction [Glucosamine results in increased expression of ERN1 mRNA]		 CTD PMID:30602124 PMID:33812996 NCBI chr17:64,039,142...64,130,144
Ensembl chr17:64,039,080...64,130,819 		JBrowse link
G FABP4 fatty acid binding protein 4 increases expression ISO Glucosamine results in increased expression of FABP4 mRNA CTD PMID:15694357 NCBI chr 8:81,478,419...81,483,233
Ensembl chr 8:81,478,419...81,483,236 		JBrowse link
G FASN fatty acid synthase increases expression EXP Glucosamine results in increased expression of FASN mRNA CTD PMID:22096489 NCBI chr17:82,078,338...82,098,236
Ensembl chr17:82,078,338...82,098,294 		JBrowse link
G FBP2 fructose-bisphosphatase 2 increases expression ISO Glucosamine results in increased expression of FBP2 mRNA CTD PMID:17178593 NCBI chr 9:94,558,720...94,593,824
Ensembl chr 9:94,558,720...94,593,824 		JBrowse link
G FGF2 fibroblast growth factor 2 multiple interactions ISO Glucosamine promotes the reaction [Glucose results in increased expression of FGF2 mRNA] CTD PMID:1518840 NCBI chr 4:122,826,682...122,898,236
Ensembl chr 4:122,826,682...122,898,236 		JBrowse link
G FGF7 fibroblast growth factor 7 decreases expression
multiple interactions		 ISO Glucosamine results in decreased expression of FGF7 mRNA
IL1B inhibits the reaction [Glucosamine results in decreased expression of FGF7 mRNA]		 CTD PMID:17109745 NCBI chr15:49,423,242...49,488,775
Ensembl chr15:49,423,237...49,488,775 		JBrowse link
G FGF9 fibroblast growth factor 9 multiple interactions
increases expression		 ISO Glucosamine inhibits the reaction [IL1B results in increased expression of FGF9 mRNA]
Glucosamine results in increased expression of FGF9 mRNA		 CTD PMID:17109745 NCBI chr13:21,671,073...21,704,498
Ensembl chr13:21,671,073...21,704,498 		JBrowse link
G FGFR1 fibroblast growth factor receptor 1 multiple interactions
increases expression		 ISO Glucosamine inhibits the reaction [IL1B results in decreased expression of FGFR1 mRNA]
Glucosamine results in increased expression of FGFR1 mRNA		 CTD PMID:17109745 NCBI chr 8:38,411,143...38,468,635
Ensembl chr 8:38,400,215...38,468,834 		JBrowse link
G FKBP11 FKBP prolyl isomerase 11 decreases expression ISO Glucosamine results in decreased expression of FKBP11 mRNA CTD PMID:17178593 NCBI chr12:48,921,963...48,939,034
Ensembl chr12:48,921,518...48,926,474 		JBrowse link
G FN1 fibronectin 1 decreases expression ISO Glucosamine results in decreased expression of FN1 protein CTD PMID:17178593 NCBI chr 2:215,360,865...215,436,068
Ensembl chr 2:215,360,440...215,436,073 		JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO
EXP		 Glucosamine analog inhibits the reaction [Buthionine Sulfoximine results in increased expression of FOS mRNA]
Glucosamine analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS protein]		 CTD PMID:19375915 PMID:21825963 NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,282,230 		JBrowse link
G FURIN furin, paired basic amino acid cleaving enzyme decreases cleavage
multiple interactions		 EXP Glucosamine results in decreased cleavage of FURIN protein alternative form
Glucosamine results in decreased glycosylation of and results in decreased activity of FURIN protein		 CTD PMID:19909832 NCBI chr15:90,868,588...90,883,457
Ensembl chr15:90,868,588...90,883,564 		JBrowse link
G FXYD2 FXYD domain containing ion transport regulator 2 increases expression ISO Glucosamine results in increased expression of FXYD2 mRNA CTD PMID:17109745 NCBI chr11:117,820,057...117,828,089
Ensembl chr11:117,800,844...117,828,698 		JBrowse link
G GATM glycine amidinotransferase decreases expression ISO Glucosamine results in decreased expression of GATM mRNA CTD PMID:17109745 NCBI chr15:45,361,124...45,402,227
Ensembl chr15:45,361,124...45,402,327 		JBrowse link
G GCK glucokinase decreases expression ISO Glucosamine results in decreased expression of GCK mRNA CTD PMID:11893929 NCBI chr 7:44,143,213...44,189,439
Ensembl chr 7:44,143,213...44,198,170 		JBrowse link
G GCLC glutamate-cysteine ligase catalytic subunit increases expression ISO Glucosamine analog results in increased expression of GCLC mRNA CTD PMID:21825963 NCBI chr 6:53,497,341...53,545,101
Ensembl chr 6:53,497,341...53,616,970 		JBrowse link
G GFPT1 glutamine--fructose-6-phosphate transaminase 1 multiple interactions ISO [Glucosamine co-treated with INS1 protein] affects the localization of GFPT1 protein CTD PMID:9453242 NCBI chr 2:69,319,780...69,387,227
Ensembl chr 2:69,319,780...69,387,250 		JBrowse link
G GLRX glutaredoxin increases expression ISO Glucosamine results in increased expression of GLRX mRNA CTD PMID:17178593 NCBI chr 5:95,813,849...95,822,726
Ensembl chr 5:95,751,319...95,822,726 		JBrowse link
G GNPNAT1 glucosamine-phosphate N-acetyltransferase 1 decreases expression ISO Glucosamine results in decreased expression of GNPNAT1 mRNA CTD PMID:17178593 NCBI chr14:52,775,193...52,791,607
Ensembl chr14:52,775,193...52,791,668 		JBrowse link
G GNPTAB N-acetylglucosamine-1-phosphate transferase subunits alpha and beta increases expression ISO Glucosamine results in increased expression of GNPTAB mRNA CTD PMID:17178593 NCBI chr12:101,745,499...101,830,959
Ensembl chr12:101,745,499...101,830,959 		JBrowse link
G GPD1L glycerol-3-phosphate dehydrogenase 1 like increases expression ISO Glucosamine results in increased expression of GPD1L mRNA CTD PMID:17178593 NCBI chr 3:32,106,620...32,168,709
Ensembl chr 3:32,105,689...32,168,709 		JBrowse link
G GREM1 gremlin 1, DAN family BMP antagonist multiple interactions
decreases expression		 ISO Glucosamine inhibits the reaction [IL1B results in increased expression of GREM1 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of GREM1 mRNA] CTD PMID:17109745 NCBI chr15:32,718,004...32,745,106
Ensembl chr15:32,718,004...32,745,106 		JBrowse link
G GSK3B glycogen synthase kinase 3 beta decreases phosphorylation
multiple interactions		 EXP Glucosamine results in decreased phosphorylation of GSK3B protein
Glucosamine inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]; NUS1 protein inhibits the reaction [Glucosamine inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]]; PRKAA1 protein promotes the reaction [Glucosamine inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]]; PRKAA1 protein promotes the reaction [NUS1 protein inhibits the reaction [Glucosamine inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]]]		 CTD PMID:33812996 NCBI chr 3:119,821,321...120,094,447
Ensembl chr 3:119,821,321...120,094,994 		JBrowse link
G GSPT1 G1 to S phase transition 1 multiple interactions EXP Glucosamine analog inhibits the reaction [TNF results in increased expression of GSPT1 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of GSPT1 mRNA] CTD PMID:18173918 NCBI chr16:11,868,128...11,916,654
Ensembl chr16:11,868,128...11,916,082 		JBrowse link
G GSTT1 glutathione S-transferase theta 1 increases expression ISO Glucosamine results in increased expression of GSTT1 mRNA CTD PMID:17178593
G HAPLN1 hyaluronan and proteoglycan link protein 1 decreases expression
multiple interactions		 ISO Glucosamine results in decreased expression of HAPLN1 mRNA
Glucosamine inhibits the reaction [IL1B results in decreased expression of HAPLN1 mRNA]; IL1B promotes the reaction [Glucosamine results in decreased expression of HAPLN1 mRNA]		 CTD PMID:17109745 NCBI chr 5:83,637,805...83,720,855
Ensembl chr 5:83,637,805...83,720,855 		JBrowse link
G HERPUD1 homocysteine inducible ER protein with ubiquitin like domain 1 decreases expression ISO Glucosamine results in decreased expression of HERPUD1 mRNA CTD PMID:17178593 NCBI chr16:56,932,142...56,944,864
Ensembl chr16:56,932,142...56,944,864 		JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha multiple interactions
decreases expression		 EXP Glucosamine affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HIF1A protein]; Glucosamine inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]
Glucosamine results in decreased expression of HIF1A mRNA; Glucosamine results in decreased expression of HIF1A protein		 CTD PMID:19254699 PMID:22020377 NCBI chr14:61,695,513...61,748,258
Ensembl chr14:61,695,513...61,748,259 		JBrowse link
G HK1 hexokinase 1 increases expression ISO Glucosamine results in increased expression of HK1 mRNA CTD PMID:11893929 PMID:17178593 NCBI chr10:69,270,000...69,401,882
Ensembl chr10:69,269,984...69,401,884 		JBrowse link
G HMGA1 high mobility group AT-hook 1 increases expression ISO Glucosamine results in increased expression of HMGA1 mRNA CTD PMID:17109745 NCBI chr 6:34,236,873...34,246,231
Ensembl chr 6:34,236,873...34,246,231 		JBrowse link
G HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 increases expression ISO Glucosamine results in increased expression of HMGCS1 mRNA CTD PMID:17178593 NCBI chr 5:43,287,470...43,313,412
Ensembl chr 5:43,287,470...43,313,512 		JBrowse link
G HMMR hyaluronan mediated motility receptor decreases expression ISO Glucosamine results in decreased expression of HMMR mRNA CTD PMID:17109745 NCBI chr 5:163,460,632...163,491,941
Ensembl chr 5:163,460,203...163,491,941 		JBrowse link
G HMOX1 heme oxygenase 1 multiple interactions
increases expression		 EXP Glucosamine inhibits the reaction [IL1B results in decreased expression of HMOX1 mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of HMOX1 protein]
Glucosamine results in increased expression of HMOX1 mRNA; Glucosamine results in increased expression of HMOX1 protein		 CTD PMID:18077487 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214 		JBrowse link
G HOXA1 homeobox A1 decreases expression ISO Glucosamine results in decreased expression of HOXA1 mRNA CTD PMID:17178593 NCBI chr 7:27,092,993...27,096,000
Ensembl chr 7:27,092,993...27,096,000 		JBrowse link
G HPGD 15-hydroxyprostaglandin dehydrogenase decreases expression ISO Glucosamine results in decreased expression of HPGD mRNA CTD PMID:17109745 NCBI chr 4:174,490,175...174,522,893
Ensembl chr 4:174,490,175...174,523,154 		JBrowse link
G HSP90B1 heat shock protein 90 beta family member 1 decreases expression
increases expression		 ISO
EXP		 Glucosamine results in decreased expression of HSP90B1 mRNA
Glucosamine results in increased expression of HSP90B1 protein		 CTD PMID:15618547 PMID:17109745 PMID:17178593 NCBI chr12:103,930,410...103,947,926
Ensembl chr12:103,930,107...103,953,931 		JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 multiple interactions
increases expression
decreases expression		 EXP
ISO		 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of HSPA5 mRNA]; NUS1 protein inhibits the reaction [Glucosamine results in increased expression of HSPA5 mRNA]; NUS1 protein inhibits the reaction [Glucosamine results in increased expression of HSPA5 protein]; ursodoxicoltaurine inhibits the reaction [Glucosamine results in increased expression of HSPA5 mRNA]
4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of HSPA5 mRNA]; 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of HSPA5 protein]
Glucosamine results in increased expression of HSPA5 mRNA; Glucosamine results in increased expression of HSPA5 protein
4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of HSPA5 mRNA]; ursodoxicoltaurine inhibits the reaction [Glucosamine results in increased expression of HSPA5 mRNA]
Glucosamine results in decreased expression of HSPA5 mRNA		 CTD PMID:15618547 PMID:16380481 PMID:17178593 PMID:19383982 PMID:20165829 More... NCBI chr 9:125,234,853...125,241,343
Ensembl chr 9:125,234,853...125,241,382 		JBrowse link
G HYOU1 hypoxia up-regulated 1 decreases expression ISO Glucosamine results in decreased expression of HYOU1 mRNA CTD PMID:17178593 NCBI chr11:119,044,188...119,057,205
Ensembl chr11:119,044,188...119,057,227 		JBrowse link
G ICAM1 intercellular adhesion molecule 1 multiple interactions
decreases activity		 EXP
ISO		 Alloxan inhibits the reaction [Glucosamine inhibits the reaction [Cathelicidins results in increased expression of ICAM1 protein]]; Glucosamine inhibits the reaction [[IL6 co-treated with TNF] results in increased expression of ICAM1 protein]; Glucosamine inhibits the reaction [Cathelicidins results in increased expression of ICAM1 mRNA]; Glucosamine inhibits the reaction [Cathelicidins results in increased expression of ICAM1 protein]; Glucosamine inhibits the reaction [IFNG promotes the reaction [TNF results in increased expression of ICAM1 protein]]; Glucosamine inhibits the reaction [IFNG results in increased expression of ICAM1 mRNA]; Glucosamine inhibits the reaction [IFNG results in increased expression of ICAM1 protein]; Glucosamine inhibits the reaction [IL1B promotes the reaction [TNF results in increased expression of ICAM1 protein]]; Glucosamine inhibits the reaction [IL1B results in increased expression of ICAM1 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of ICAM1 protein]; Glucosamine inhibits the reaction [IL6 results in increased expression of ICAM1 protein]; Glucosamine inhibits the reaction [TNF promotes the reaction [IFNG results in increased expression of ICAM1 protein]]; Glucosamine inhibits the reaction [TNF promotes the reaction [IL1B results in increased expression of ICAM1 protein]]; Glucosamine inhibits the reaction [TNF results in increased expression of ICAM1 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of ICAM1 protein]
Glucosamine results in decreased activity of ICAM1 protein
Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of ICAM1 protein]		 CTD PMID:16431966 PMID:16822504 PMID:17238806 PMID:18949387 PMID:19020780 More... NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615 		JBrowse link
G ID1 inhibitor of DNA binding 1 increases expression ISO Glucosamine results in increased expression of ID1 mRNA CTD PMID:17178593 NCBI chr20:31,605,289...31,606,510
Ensembl chr20:31,605,283...31,606,515 		JBrowse link
G ID2 inhibitor of DNA binding 2 increases expression ISO Glucosamine results in increased expression of ID2 mRNA CTD PMID:17178593 NCBI chr 2:8,682,056...8,684,461
Ensembl chr 2:8,678,845...8,684,461 		JBrowse link
G ID3 inhibitor of DNA binding 3 increases expression ISO Glucosamine results in increased expression of ID3 mRNA CTD PMID:17178593 NCBI chr 1:23,557,926...23,559,501
Ensembl chr 1:23,557,926...23,559,501 		JBrowse link
G IDH1 isocitrate dehydrogenase (NADP(+)) 1 increases expression ISO Glucosamine results in increased expression of IDH1 mRNA CTD PMID:17178593 NCBI chr 2:208,236,227...208,255,071
Ensembl chr 2:208,236,229...208,266,074 		JBrowse link
G IFI16 interferon gamma inducible protein 16 increases expression ISO Glucosamine results in increased expression of IFI204 mRNA CTD PMID:17178593 NCBI chr 1:158,999,976...159,055,151
Ensembl chr 1:158,999,968...159,055,155 		JBrowse link
G IFIT1B interferon induced protein with tetratricopeptide repeats 1B increases expression ISO Glucosamine results in increased expression of IFIT1 mRNA CTD PMID:17178593 NCBI chr10:89,378,056...89,385,205
Ensembl chr10:89,378,056...89,385,205 		JBrowse link
G IFIT3 interferon induced protein with tetratricopeptide repeats 3 increases expression ISO Glucosamine results in increased expression of IFIT3 mRNA CTD PMID:17178593 NCBI chr10:89,327,997...89,340,968
Ensembl chr10:89,327,307...89,377,473 		JBrowse link
G IFNG interferon gamma decreases secretion
multiple interactions		 ISO
EXP		 Glucosamine results in decreased secretion of IFNG protein
Glucosamine inhibits the reaction [IFNG promotes the reaction [TNF results in increased expression of ICAM1 protein]]; Glucosamine inhibits the reaction [IFNG results in increased expression of ICAM1 mRNA]; Glucosamine inhibits the reaction [IFNG results in increased expression of ICAM1 protein]; Glucosamine inhibits the reaction [IFNG results in increased localization of STAT1 protein modified form]; Glucosamine inhibits the reaction [IFNG results in increased phosphorylation of and results in increased localization of STAT1 protein]; Glucosamine inhibits the reaction [TNF promotes the reaction [IFNG results in increased expression of ICAM1 protein]]		 CTD PMID:14507305 PMID:16431966 PMID:16822504 PMID:17238806 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740 		JBrowse link
G IGFBP3 insulin like growth factor binding protein 3 multiple interactions
decreases expression		 ISO Glucosamine inhibits the reaction [IL1B results in increased expression of IGFBP3 mRNA]; IL1B inhibits the reaction [Glucosamine results in increased expression of IGFBP3 mRNA]
Glucosamine results in decreased expression of IGFBP3 mRNA		 CTD PMID:17109745 NCBI chr 7:45,912,245...45,921,272
Ensembl chr 7:45,912,245...45,921,874 		JBrowse link
G IGFBP4 insulin like growth factor binding protein 4 decreases expression ISO Glucosamine results in decreased expression of IGFBP4 mRNA CTD PMID:17178593 NCBI chr17:40,443,450...40,457,725
Ensembl chr17:40,443,450...40,457,725 		JBrowse link
G IGFBP5 insulin like growth factor binding protein 5 multiple interactions
increases expression		 ISO Glucosamine inhibits the reaction [IL1B results in increased expression of IGFBP5 mRNA]
Glucosamine results in increased expression of IGFBP5 mRNA		 CTD PMID:17109745 NCBI chr 2:216,672,105...216,695,549
Ensembl chr 2:216,672,105...216,695,549 		JBrowse link
G IKBKB inhibitor of nuclear factor kappa B kinase subunit beta multiple interactions ISO Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased expression of IKBKB protein] CTD PMID:18786831 NCBI chr 8:42,271,302...42,332,460
Ensembl chr 8:42,271,302...42,332,460 		JBrowse link
G IKBKG inhibitor of nuclear factor kappa B kinase regulatory subunit gamma multiple interactions
decreases expression		 ISO Glucosamine inhibits the reaction [IL1B results in increased expression of IKBKG mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of IKBKG mRNA] CTD PMID:17109745 NCBI chr  X:154,541,238...154,565,046
Ensembl chr  X:154,541,199...154,565,046 		JBrowse link
G IL11 interleukin 11 multiple interactions ISO Glucosamine inhibits the reaction [IL1B results in increased expression of IL11 mRNA] CTD PMID:17109745 NCBI chr19:55,364,382...55,370,463
Ensembl chr19:55,364,382...55,370,463 		JBrowse link
G IL13RA1 interleukin 13 receptor subunit alpha 1 multiple interactions
decreases expression		 ISO Glucosamine inhibits the reaction [IL1B results in increased expression of IL13RA1 mRNA]
Glucosamine results in decreased expression of IL13RA1 mRNA		 CTD PMID:17109745 NCBI chr  X:118,727,606...118,805,228
Ensembl chr  X:118,727,133...118,794,535 		JBrowse link
G IL1A interleukin 1 alpha multiple interactions
increases expression		 ISO Glucosamine inhibits the reaction [IL1B results in increased expression of IL1A mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of IL1A mRNA] CTD PMID:17109745 NCBI chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493 		JBrowse link
G IL1B interleukin 1 beta multiple interactions
increases expression
decreases expression		 EXP
ISO		 [Glucosamine co-treated with Chondroitin Sulfates co-treated with IL1B protein] results in decreased expression of NOS2 protein; [Glucosamine co-treated with Chondroitin Sulfates co-treated with IL1B protein] results in decreased expression of PTGES protein; [Glucosamine co-treated with Chondroitin Sulfates co-treated with IL1B protein] results in decreased expression of PTGS2 protein; [Glucosamine co-treated with Chondroitin Sulfates co-treated with IL1B protein] results in increased expression of TIMP3 mRNA; [Glucosamine co-treated with Chondroitin Sulfates] inhibits the reaction [IL1B protein results in increased secretion of Dinoprostone]; [Glucosamine co-treated with Chondroitin Sulfates] inhibits the reaction [IL1B protein results in increased secretion of Nitrites]; Glucosamine analog affects the reaction [IL1B protein results in increased abundance of Nitric Oxide]; Glucosamine analog affects the reaction [IL1B results in decreased expression of ACAN mRNA]; Glucosamine analog affects the reaction [IL1B results in decreased expression of COL2A1 mRNA]; Glucosamine analog affects the reaction [IL1B results in increased phosphorylation of AKT1 protein]; Glucosamine analog inhibits the reaction [IL1B protein results in increased abundance of Dinoprostone]; Glucosamine analog inhibits the reaction [IL1B protein results in increased expression of MMP13]; Glucosamine analog inhibits the reaction [IL1B protein results in increased expression of MMP1]; Glucosamine analog inhibits the reaction [IL1B protein results in increased expression of MMP3]; Glucosamine analog inhibits the reaction [IL1B results in increased expression of and results in increased secretion of MMP1 protein]; Glucosamine analog inhibits the reaction [IL1B results in increased expression of and results in increased secretion of MMP13 protein]; Glucosamine analog inhibits the reaction [IL1B results in increased expression of and results in increased secretion of MMP3 protein]; Glucosamine analog inhibits the reaction [IL1B results in increased expression of CXCL8 mRNA]; Glucosamine analog inhibits the reaction [IL1B results in increased expression of MMP1 mRNA]; Glucosamine analog inhibits the reaction [IL1B results in increased expression of MMP13 mRNA]; Glucosamine analog inhibits the reaction [IL1B results in increased expression of MMP3 mRNA]; Glucosamine analog inhibits the reaction [IL1B results in increased localization of RELA protein]; Glucosamine analog inhibits the reaction [IL1B results in increased phosphorylation of and results in increased degradation of NFKBIA protein]; Glucosamine analog inhibits the reaction [IL1B results in increased secretion of CCL2 protein]; Glucosamine analog inhibits the reaction [IL1B results in increased secretion of CCL5 protein]; Glucosamine analog inhibits the reaction [IL1B results in increased secretion of CXCL8 protein]; Glucosamine analog promotes the reaction [IL1B results in increased phosphorylation of MAPK1 protein]; Glucosamine analog promotes the reaction [IL1B results in increased phosphorylation of MAPK3 protein]; Glucosamine analog promotes the reaction [IL1B results in increased phosphorylation of MAPK8 protein]; Glucosamine inhibits the reaction [[OSM protein co-treated with IL1B protein] results in decreased methylation of IL1B promoter]; Glucosamine inhibits the reaction [[OSM protein co-treated with IL1B protein] results in increased expression of IL1B mRNA]; Glucosamine inhibits the reaction [IL1B promotes the reaction [TNF results in increased expression of ICAM1 protein]]; Glucosamine inhibits the reaction [IL1B protein results in decreased expression of ACAN mRNA]; Glucosamine inhibits the reaction [IL1B protein results in decreased expression of COL2A1 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased activity of JUN protein]; Glucosamine inhibits the reaction [IL1B protein results in increased activity of JUND protein]; Glucosamine inhibits the reaction [IL1B protein results in increased degradation of NFKBIA protein]; Glucosamine inhibits the reaction [IL1B protein results in increased expression of COL1A1 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased expression of MMP1 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased expression of MMP13 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased expression of MMP3 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased expression of PTGS2 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased expression of PTGS2 protein]; Glucosamine inhibits the reaction [IL1B protein results in increased localization of NFKB1 protein]; Glucosamine inhibits the reaction [IL1B protein results in increased localization of RELA protein]; Glucosamine inhibits the reaction [IL1B protein results in increased secretion of Dinoprostone]; Glucosamine inhibits the reaction [IL1B protein results in increased secretion of MMP1 protein]; Glucosamine inhibits the reaction [IL1B protein results in increased secretion of MMP13 protein]; Glucosamine inhibits the reaction [IL1B protein results in increased secretion of MMP3 protein]; Glucosamine inhibits the reaction [IL1B results in decreased expression of HMOX1 mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of HMOX1 protein]; Glucosamine inhibits the reaction [IL1B results in increased abundance of Dinoprostone]; Glucosamine inhibits the reaction [IL1B results in increased abundance of Nitric Oxide]; Glucosamine inhibits the reaction [IL1B results in increased abundance of Nitrites]; Glucosamine inhibits the reaction [IL1B results in increased degradation of NFKB1 protein]; Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL8 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL8 protein]; Glucosamine inhibits the reaction [IL1B results in increased expression of ICAM1 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of ICAM1 protein]; Glucosamine inhibits the reaction [IL1B results in increased expression of MMP3 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of MMP3 protein]; Glucosamine inhibits the reaction [IL1B results in increased expression of NOS2 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of PTGES mRNA]; Glucosamine inhibits the reaction [IL1B results in increased localization of RELA protein]; Glucosamine inhibits the reaction [IL1B results in increased phosphorylation of MAPK1 protein]; Glucosamine inhibits the reaction [IL1B results in increased phosphorylation of MAPK14 protein]; Glucosamine inhibits the reaction [IL1B results in increased phosphorylation of MAPK3 protein]; Glucosamine inhibits the reaction [IL1B results in increased phosphorylation of MAPK8 protein]; Glucosamine inhibits the reaction [IL1B results in increased secretion of CXCL8 protein]; Glucosamine inhibits the reaction [TNF promotes the reaction [IL1B results in increased expression of ICAM1 protein]]; Glucosamine promotes the reaction [IL1B results in increased expression of PPARG]; Glucosamine promotes the reaction [IL1B results in increased phosphorylation of AKT1 protein]
Glucosamine results in increased expression of IL1B mRNA
Glucosamine results in decreased expression of IL1B mRNA
[IL1B protein co-treated with Glucosamine] results in increased expression of IL1R2 mRNA; Glucosamine affects the reaction [IL1B results in decreased expression of ADAM15 mRNA]; Glucosamine affects the reaction [IL1B results in decreased expression of OAT mRNA]; Glucosamine inhibits the reaction [IL1B protein results in decreased activity of B3GAT3 protein]; Glucosamine inhibits the reaction [IL1B protein results in decreased expression of B3GAT3 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased abundance of Dinoprostone]; Glucosamine inhibits the reaction [IL1B protein results in increased abundance of Nitric Oxide]; Glucosamine inhibits the reaction [IL1B protein results in increased expression of MMP3 mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of ACAN mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of COL11A1 mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of COL2A1 mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of COL3A1 mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of FGFR1 mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of HAPLN1 mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of LAMA4 mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of SDC2 mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of SOX4 mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of THBS4 mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of TIMP2 mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of TIMP3 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of ADAM17 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of ADAMTS1 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of ASS1 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of BGN mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of BMP2 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of BMP6 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of BMP7 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CCL2 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CCL20 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CCL22 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CCL3 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CCL5 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CCL7 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of COL8A1 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CSF1 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CSF2 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CSF3 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL1 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL10 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL11 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL2 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL3 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL5 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of DUSP5 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of DUSP7 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of EPAS1 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of FGF9 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of GREM1 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of IGFBP3 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of IGFBP5 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of IKBKG mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of IL11 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of IL13RA1 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of IL1A mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of IL1B mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of IL23R mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of IL6 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of JAK2 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of JUNB mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of MMP10 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of MMP12 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of MMP13 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of MMP3 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of MMP9 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of NFKBIA mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of NFKBIB mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of NGF mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of NOS2 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of PDGFA mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of PLA2G2A mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of PLA2G4A mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of PLA2G5 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of RELB mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of SDC4 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of SLC7A8 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of TIMP1 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of TNFAIP6 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of TNK2 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of VCAN mRNA]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; Glucosamine promotes the reaction [IL1B results in decreased expression of BMP4 mRNA]; Glucosamine promotes the reaction [IL1B results in decreased expression of CXCL12 mRNA]; IL1B affects the reaction [Glucosamine affects the expression of PDGFA mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of ADAM15 mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of BGN mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of COL11A1 mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of CXCL12 mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of DUSP7 mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of EPAS1 mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of IKBKG mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of JUNB mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of TNFAIP6 mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of VCAN mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of ADAM17 mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of IL1A mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of JAK2 mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of LAMA4 mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of MMP9 mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of NFKBIB mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of TIMP3 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of ADAMTS1 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of COL8A1 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of CSF1 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of CXCL1 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of FGF7 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of GREM1 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of NFKBIA mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of PLA2G2A mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of PLA2G5 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of SDC4 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of SLC7A8 mRNA]; IL1B inhibits the reaction [Glucosamine results in increased expression of IGFBP3 mRNA]; IL1B promotes the reaction [Glucosamine results in decreased expression of HAPLN1 mRNA]; IL1B promotes the reaction [Glucosamine results in decreased expression of SDC2 mRNA]; IL1B promotes the reaction [Glucosamine results in decreased expression of THBS4 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of AZIN1 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of CCL2 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of CCL20 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of CCL7 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of CXCL2 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of CXCL3 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of MMP10 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of MMP12 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of MMP13 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of MMP2 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of MMP3 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of NOS2 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of TIMP1 mRNA]
Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased secretion of IL1B protein]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]		 CTD PMID:11229466 PMID:11801247 PMID:12681956 PMID:15144122 PMID:16822504 More... NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL1R2 interleukin 1 receptor type 2 multiple interactions ISO [IL1B protein co-treated with Glucosamine] results in increased expression of IL1R2 mRNA CTD PMID:11801247 NCBI chr 2:101,991,960...102,028,544
Ensembl chr 2:101,991,960...102,028,544 		JBrowse link
G IL2 interleukin 2 decreases secretion ISO Glucosamine results in decreased secretion of IL2 protein CTD PMID:14507305 NCBI chr 4:122,451,470...122,456,725
Ensembl chr 4:122,451,470...122,456,725 		JBrowse link
G IL23R interleukin 23 receptor multiple interactions ISO Glucosamine inhibits the reaction [IL1B results in increased expression of IL23R mRNA] CTD PMID:17109745 NCBI chr 1:67,138,637...67,265,903
Ensembl chr 1:67,138,907...67,259,979 		JBrowse link
G IL33 interleukin 33 decreases expression ISO Glucosamine results in decreased expression of IL33 mRNA CTD PMID:17109745 NCBI chr 9:6,215,149...6,257,983
Ensembl chr 9:6,215,786...6,257,983 		JBrowse link
G IL4 interleukin 4 decreases secretion
decreases expression		 ISO
EXP		 Glucosamine results in decreased secretion of IL4 protein
Glucosamine results in decreased expression of IL4		 CTD PMID:14507305 PMID:21284687 NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678 		JBrowse link
G IL5 interleukin 5 decreases secretion
decreases expression		 ISO
EXP		 Glucosamine results in decreased secretion of IL5 protein
Glucosamine results in decreased expression of IL5		 CTD PMID:14507305 PMID:21284687 NCBI chr 5:132,541,445...132,556,815
Ensembl chr 5:132,541,445...132,556,838 		JBrowse link
G IL6 interleukin 6 multiple interactions
decreases expression		 EXP
ISO		 Glucosamine analog inhibits the reaction [TNF results in increased expression of IL6 mRNA]; Glucosamine inhibits the reaction [[IL6 co-treated with TNF] results in increased expression of ICAM1 protein]; Glucosamine inhibits the reaction [IL6 results in increased expression of ICAM1 protein]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased secretion of IL6 protein]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of IL6 mRNA]
Glucosamine inhibits the reaction [IL1B results in increased expression of IL6 mRNA]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]
Glucosamine analog results in decreased expression of IL6 mRNA; Glucosamine results in decreased expression of IL6 mRNA
Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased secretion of IL6 protein]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]		 CTD PMID:16822504 PMID:17109745 PMID:18786831 PMID:19098112 PMID:20093129 More... NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G INPP5K inositol polyphosphate-5-phosphatase K multiple interactions
increases expression		 EXP NUS1 protein inhibits the reaction [Glucosamine results in increased expression of INPP5K mRNA] CTD PMID:33812996 NCBI chr17:1,494,577...1,516,612
Ensembl chr17:1,494,577...1,516,742 		JBrowse link
G INS insulin multiple interactions EXP 4-phenylbutyric acid inhibits the reaction [Glucosamine inhibits the reaction [INS results in increased uptake of Deoxyglucose]]; Glucosamine inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]; Glucosamine inhibits the reaction [INS results in increased uptake of Deoxyglucose]; NUS1 protein inhibits the reaction [Glucosamine inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]]; PRKAA1 protein promotes the reaction [Glucosamine inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]]; PRKAA1 protein promotes the reaction [NUS1 protein inhibits the reaction [Glucosamine inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]]]; ursodoxicoltaurine inhibits the reaction [Glucosamine inhibits the reaction [INS results in increased uptake of Deoxyglucose]] CTD PMID:20165829 PMID:33812996 NCBI chr11:2,159,779...2,161,209
Ensembl chr11:2,159,779...2,161,221 		JBrowse link
G INS-IGF2 INS-IGF2 readthrough multiple interactions ISO 4-phenylbutyric acid inhibits the reaction [Glucosamine inhibits the reaction [INS1 results in increased uptake of Deoxyglucose]]; [Glucosamine co-treated with INS1 protein] affects the localization of GFPT1 protein; Glucosamine inhibits the reaction [Glucose results in increased secretion of INS1 protein]; Glucosamine inhibits the reaction [INS1 protein results in increased uptake of Deoxyglucose]; Glucosamine inhibits the reaction [INS1 results in increased uptake of Deoxyglucose]; ursodoxicoltaurine inhibits the reaction [Glucosamine inhibits the reaction [INS1 results in increased uptake of Deoxyglucose]]
[INS1 protein co-treated with Glucosamine] results in increased expression of OSTN mRNA; Glucosamine inhibits the reaction [INS1 protein results in increased phosphorylation of AKT1 protein]; Glucosamine inhibits the reaction [INS1 protein results in increased uptake of 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose]; INS1 inhibits the reaction [[Streptozocin co-treated with APOE mutant form] results in increased abundance of Glucosamine]; OSTN protein affects the reaction [Glucosamine inhibits the reaction [INS1 protein results in increased phosphorylation of AKT1 protein]]; OSTN protein affects the reaction [Glucosamine inhibits the reaction [INS1 protein results in increased uptake of 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose]]		 CTD PMID:9453242 PMID:11893929 PMID:16380481 PMID:20165829 PMID:30602124 NCBI chr11:2,129,117...2,161,209
Ensembl chr11:2,132,538...2,161,209 		JBrowse link
G IRF1 interferon regulatory factor 1 multiple interactions ISO Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of IRF1 mRNA] CTD PMID:20737476 NCBI chr 5:132,481,609...132,490,773
Ensembl chr 5:132,440,440...132,508,719 		JBrowse link
G ISYNA1 inositol-3-phosphate synthase 1 increases expression ISO Glucosamine results in increased expression of ISYNA1 mRNA CTD PMID:17109745 NCBI chr19:18,434,388...18,438,133
Ensembl chr19:18,434,388...18,438,167 		JBrowse link
G JAK2 Janus kinase 2 multiple interactions
increases expression		 ISO Glucosamine inhibits the reaction [IL1B results in increased expression of JAK2 mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of JAK2 mRNA] CTD PMID:17109745 NCBI chr 9:4,984,390...5,129,948
Ensembl chr 9:4,984,390...5,129,948 		JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP
ISO		 Glucosamine inhibits the reaction [IL1B protein results in increased activity of JUN protein]
Glucosamine analog inhibits the reaction [Buthionine Sulfoximine results in increased expression of JUN mRNA]		 CTD PMID:17925024 PMID:21825963 NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,776,845...58,784,048 		JBrowse link
G JUNB JunB proto-oncogene, AP-1 transcription factor subunit multiple interactions
decreases expression		 ISO Glucosamine inhibits the reaction [IL1B results in increased expression of JUNB mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of JUNB mRNA] CTD PMID:17109745 NCBI chr19:12,791,486...12,793,315
Ensembl chr19:12,791,486...12,793,315 		JBrowse link
G JUND JunD proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP Glucosamine inhibits the reaction [IL1B protein results in increased activity of JUND protein] CTD PMID:17925024 NCBI chr19:18,279,694...18,281,622
Ensembl chr19:18,279,694...18,281,622 		JBrowse link
G KCNJ16 potassium inwardly rectifying channel subfamily J member 16 increases expression ISO Glucosamine results in increased expression of KCNJ16 mRNA CTD PMID:17178593 NCBI chr17:70,075,225...70,135,608
Ensembl chr17:70,053,429...70,135,608 		JBrowse link
G KIF11 kinesin family member 11 decreases expression ISO Glucosamine results in decreased expression of KIF11 mRNA CTD PMID:17109745 NCBI chr10:92,593,130...92,655,395
Ensembl chr10:92,574,105...92,655,395 		JBrowse link
G KIF4A kinesin family member 4A decreases expression ISO Glucosamine results in decreased expression of KIF4A mRNA CTD PMID:17109745 NCBI chr  X:70,290,104...70,420,886
Ensembl chr  X:70,290,104...70,420,886 		JBrowse link
G KLF10 KLF transcription factor 10 increases expression ISO Glucosamine results in increased expression of KLF10 mRNA CTD PMID:17178593 NCBI chr 8:102,648,784...102,655,725
Ensembl chr 8:102,648,784...102,655,725 		JBrowse link
G LAMA4 laminin subunit alpha 4 multiple interactions
increases expression		 ISO Glucosamine inhibits the reaction [IL1B results in decreased expression of LAMA4 mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of LAMA4 mRNA] CTD PMID:17109745 NCBI chr 6:112,107,931...112,254,985
Ensembl chr 6:112,107,931...112,254,939 		JBrowse link
G LAMB1 laminin subunit beta 1 multiple interactions ISO TXNIP promotes the reaction [Glucosamine results in increased expression of LAMB1 mRNA] CTD PMID:17178593 NCBI chr 7:107,923,799...108,003,161
Ensembl chr 7:107,923,799...108,003,213 		JBrowse link
G LAMC1 laminin subunit gamma 1 multiple interactions ISO TXNIP promotes the reaction [Glucosamine results in increased expression of LAMC1 mRNA] CTD PMID:17178593 NCBI chr 1:183,023,420...183,145,592
Ensembl chr 1:183,023,420...183,145,592 		JBrowse link
G LCN2 lipocalin 2 decreases expression ISO Glucosamine results in decreased expression of LCN2 mRNA CTD PMID:17178593 NCBI chr 9:128,149,453...128,153,453
Ensembl chr 9:128,149,071...128,153,453 		JBrowse link
G LEPR leptin receptor affects response to substance
multiple interactions		 ISO LEPR protein affects the susceptibility to Glucosamine
[LEPR protein affects the susceptibility to Glucosamine] which affects the expression of ALB protein		 CTD PMID:33345901 NCBI chr 1:65,420,652...65,641,559
Ensembl chr 1:65,420,652...65,641,559 		JBrowse link
G LPIN1 lipin 1 increases expression ISO Glucosamine results in increased expression of LPIN1 mRNA CTD PMID:17178593 NCBI chr 2:11,677,544...11,827,409
Ensembl chr 2:11,677,595...11,827,409 		JBrowse link
G LY6S lymphocyte antigen 6 family member S increases expression ISO Glucosamine results in increased expression of LY6A mRNA CTD PMID:17178593 NCBI chr 8:143,040,839...143,076,471
Ensembl chr 8:143,040,839...143,048,319 		JBrowse link
G MAFB MAF bZIP transcription factor B increases expression ISO Glucosamine results in increased expression of MAFB mRNA CTD PMID:17109745 NCBI chr20:40,685,848...40,689,236
Ensembl chr20:40,685,848...40,689,236 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 multiple interactions
increases phosphorylation		 EXP Glucosamine analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MAPK1 protein]; Glucosamine analog promotes the reaction [IL1B results in increased phosphorylation of MAPK1 protein]; Glucosamine inhibits the reaction [IL1B results in increased phosphorylation of MAPK1 protein]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]
Glucosamine analog results in increased phosphorylation of MAPK1 protein		 CTD PMID:18080321 PMID:18340449 PMID:19375915 PMID:19626664 PMID:20307528 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680 		JBrowse link
G MAPK14 mitogen-activated protein kinase 14 multiple interactions EXP Glucosamine inhibits the reaction [IL1B results in increased phosphorylation of MAPK14 protein] CTD PMID:19626664 NCBI chr 6:36,027,808...36,124,214
Ensembl chr 6:36,027,782...36,111,236 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 multiple interactions
increases phosphorylation		 EXP Glucosamine analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MAPK3 protein]; Glucosamine analog promotes the reaction [IL1B results in increased phosphorylation of MAPK3 protein]; Glucosamine inhibits the reaction [IL1B results in increased phosphorylation of MAPK3 protein]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK3 protein]
Glucosamine analog results in increased phosphorylation of MAPK3 protein		 CTD PMID:18080321 PMID:18340449 PMID:19375915 PMID:19626664 PMID:20307528 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506 		JBrowse link
G MAPK8 mitogen-activated protein kinase 8 multiple interactions
increases phosphorylation		 EXP Glucosamine analog promotes the reaction [IL1B results in increased phosphorylation of MAPK8 protein]; Glucosamine inhibits the reaction [IL1B results in increased phosphorylation of MAPK8 protein]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein]
Glucosamine analog results in increased phosphorylation of MAPK8 protein		 CTD PMID:18080321 PMID:19626664 PMID:20307528 NCBI chr10:48,306,677...48,439,360
Ensembl chr10:48,306,639...48,439,360 		JBrowse link
G MCL1 MCL1 apoptosis regulator, BCL2 family member decreases expression EXP Glucosamine results in decreased expression of MCL1 mRNA; Glucosamine results in decreased expression of MCL1 protein CTD PMID:22020377 NCBI chr 1:150,574,558...150,579,610
Ensembl chr 1:150,560,895...150,579,738 		JBrowse link
G MEF2A myocyte enhancer factor 2A multiple interactions
decreases expression		 EXP
ISO		 4-phenylbutyric acid inhibits the reaction [Glucosamine results in decreased expression of MEF2A mRNA]; 4-phenylbutyric acid inhibits the reaction [Glucosamine results in decreased expression of MEF2A protein]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of MEF2A mRNA]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of MEF2A protein]; ursodoxicoltaurine inhibits the reaction [Glucosamine results in decreased expression of MEF2A mRNA]; ursodoxicoltaurine inhibits the reaction [Glucosamine results in decreased expression of MEF2A protein]
Glucosamine results in decreased expression of MEF2A mRNA; Glucosamine results in decreased expression of MEF2A protein		 CTD PMID:20165829 NCBI chr15:99,565,417...99,716,488
Ensembl chr15:99,565,417...99,716,488 		JBrowse link
G METTL1 methyltransferase 1, tRNA methylguanosine decreases expression ISO Glucosamine results in decreased expression of METTL1 mRNA CTD PMID:17178593 NCBI chr12:57,768,471...57,772,105
Ensembl chr12:57,768,471...57,772,119 		JBrowse link
G MFAP3L microfibril associated protein 3 like increases expression ISO Glucosamine results in increased expression of MFAP3L mRNA CTD PMID:17178593 NCBI chr 4:169,986,602...170,027,277
Ensembl chr 4:169,986,597...170,033,031 		JBrowse link
G MKI67 marker of proliferation Ki-67 decreases expression ISO Glucosamine results in decreased expression of MKI67 mRNA CTD PMID:17109745 NCBI chr10:128,096,659...128,126,423
Ensembl chr10:128,096,659...128,126,423 		JBrowse link
G MMP1 matrix metallopeptidase 1 multiple interactions EXP Glucosamine analog inhibits the reaction [IL1B protein results in increased expression of MMP1]; Glucosamine analog inhibits the reaction [IL1B results in increased expression of and results in increased secretion of MMP1 protein]; Glucosamine analog inhibits the reaction [IL1B results in increased expression of MMP1 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased expression of MMP1 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased secretion of MMP1 protein] CTD PMID:15144122 PMID:17925024 PMID:18080321 NCBI chr11:102,789,919...102,798,160
Ensembl chr11:102,789,401...102,798,160 		JBrowse link
G MMP10 matrix metallopeptidase 10 increases expression
multiple interactions		 ISO Glucosamine results in increased expression of MMP10 mRNA
Glucosamine inhibits the reaction [IL1B results in increased expression of MMP10 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of MMP10 mRNA]		 CTD PMID:17109745 NCBI chr11:102,770,502...102,780,628
Ensembl chr11:102,770,502...102,780,628 		JBrowse link
G MMP12 matrix metallopeptidase 12 multiple interactions
increases expression		 ISO Glucosamine inhibits the reaction [IL1B results in increased expression of MMP12 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of MMP12 mRNA] CTD PMID:17109745 NCBI chr11:102,862,736...102,874,982
Ensembl chr11:102,862,736...102,874,982 		JBrowse link
G MMP13 matrix metallopeptidase 13 affects expression
multiple interactions
increases expression		 EXP
ISO		 Glucosamine analog affects the expression of MMP13 mRNA
Glucosamine inhibits the reaction [IL1B results in increased expression of MMP13 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of MMP13 mRNA]
Glucosamine analog inhibits the reaction [IL1B protein results in increased expression of MMP13]; Glucosamine analog inhibits the reaction [IL1B results in increased expression of and results in increased secretion of MMP13 protein]; Glucosamine analog inhibits the reaction [IL1B results in increased expression of MMP13 mRNA]; Glucosamine analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP13 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased expression of MMP13 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased secretion of MMP13 protein]		 CTD PMID:15144122 PMID:17109745 PMID:17337215 PMID:17925024 PMID:18080321 More... NCBI chr11:102,942,995...102,955,732
Ensembl chr11:102,942,995...102,955,732 		JBrowse link
G MMP2 matrix metallopeptidase 2 multiple interactions
increases expression		 EXP
ISO		 Glucosamine analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of MMP2 protein]; Glucosamine analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP2 mRNA]; Glucosamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP2 mRNA]; Glucosamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP2 protein]
IL1B promotes the reaction [Glucosamine results in increased expression of MMP2 mRNA]		 CTD PMID:17109745 PMID:17498959 PMID:19375915 NCBI chr16:55,478,830...55,506,691
Ensembl chr16:55,389,700...55,506,691 		JBrowse link
G MMP3 matrix metallopeptidase 3 multiple interactions
increases expression
decreases expression		 EXP
ISO		 [Glucosamine co-treated with Chondroitin Sulfates] results in decreased expression of MMP3 mRNA; [Glucosamine co-treated with Chondroitin Sulfates] results in decreased secretion of MMP3 protein; Glucosamine analog inhibits the reaction [IL1B protein results in increased expression of MMP3]; Glucosamine analog inhibits the reaction [IL1B results in increased expression of and results in increased secretion of MMP3 protein]; Glucosamine analog inhibits the reaction [IL1B results in increased expression of MMP3 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased expression of MMP3 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased secretion of MMP3 protein]; Glucosamine inhibits the reaction [IL1B results in increased expression of MMP3 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of MMP3 protein]; Glucosamine results in decreased expression of and results in decreased activity of MMP3 protein
Glucosamine results in increased expression of MMP3 mRNA
Glucosamine inhibits the reaction [IL1B protein results in increased expression of MMP3 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of MMP3 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of MMP3 mRNA]
Glucosamine analog results in decreased expression of MMP3 mRNA		 CTD PMID:11229466 PMID:12801482 PMID:15144122 PMID:16300972 PMID:17109745 More... NCBI chr11:102,835,801...102,843,609
Ensembl chr11:102,835,801...102,843,609 		JBrowse link
G MMP9 matrix metallopeptidase 9 multiple interactions
increases expression		 EXP
ISO		 Glucosamine analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of MMP9 protein]; Glucosamine analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; Glucosamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; Glucosamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 protein]
Glucosamine results in increased expression of MMP9 mRNA
Glucosamine inhibits the reaction [IL1B results in increased expression of MMP9 mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of MMP9 mRNA]		 CTD PMID:17109745 PMID:17498959 PMID:19375915 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561 		JBrowse link
G MPO myeloperoxidase decreases activity ISO Glucosamine results in decreased activity of MPO protein CTD PMID:19098112 NCBI chr17:58,269,855...58,280,935
Ensembl chr17:58,269,855...58,280,935 		JBrowse link
G MVD mevalonate diphosphate decarboxylase increases expression ISO Glucosamine results in increased expression of MVD mRNA CTD PMID:17178593 NCBI chr16:88,651,940...88,663,091
Ensembl chr16:88,651,935...88,663,161 		JBrowse link
G NDUFA4 NDUFA4 mitochondrial complex associated increases expression ISO Glucosamine results in increased expression of NDUFA4 mRNA CTD PMID:17109745 NCBI chr 7:10,931,943...10,940,153
Ensembl chr 7:10,931,943...10,940,153 		JBrowse link
G NEDD4 NEDD4 E3 ubiquitin protein ligase decreases expression ISO Glucosamine results in decreased expression of NEDD4 mRNA CTD PMID:17109745 NCBI chr15:55,826,917...55,993,612
Ensembl chr15:55,826,922...55,993,660 		JBrowse link
G NFKB1 nuclear factor kappa B subunit 1 multiple interactions
decreases activity		 EXP
ISO		 Glucosamine inhibits the reaction [Hydrogen Peroxide results in increased expression of and results in increased localization of NFKB1 protein]; Glucosamine inhibits the reaction [IL1B protein results in increased localization of NFKB1 protein]; Glucosamine inhibits the reaction [IL1B results in increased degradation of NFKB1 protein]; Glucosamine inhibits the reaction [NFKB1 results in increased degradation of RELA protein]; Glucosamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NFKB1 protein]
Glucosamine results in decreased activity of NFKB1 protein
Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased expression of NFKB1 protein]		 CTD PMID:12681956 PMID:16431966 PMID:16822504 PMID:17498959 PMID:18036590 More... NCBI chr 4:102,501,359...102,617,302
Ensembl chr 4:102,501,330...102,617,302 		JBrowse link
G NFKBIA NFKB inhibitor alpha multiple interactions
decreases phosphorylation
decreases expression		 EXP
ISO		 Glucosamine analog inhibits the reaction [IL1B results in increased phosphorylation of and results in increased degradation of NFKBIA protein]; Glucosamine inhibits the reaction [IL1B protein results in increased degradation of NFKBIA protein]
Glucosamine results in decreased phosphorylation of NFKBIA protein
Glucosamine results in decreased expression of NFKBIA mRNA
Glucosamine inhibits the reaction [IL1B results in increased expression of NFKBIA mRNA]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of NFKBIA protein]; IL1B inhibits the reaction [Glucosamine results in decreased expression of NFKBIA mRNA]
Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased expression of NFKBIA protein modified form]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of NFKBIA protein]		 CTD PMID:12681956 PMID:17109745 PMID:18080321 PMID:18205790 PMID:19098112 NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749 		JBrowse link
G NFKBIB NFKB inhibitor beta multiple interactions
increases expression		 ISO Glucosamine inhibits the reaction [IL1B results in increased expression of NFKBIB mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of NFKBIB mRNA] CTD PMID:17109745 NCBI chr19:38,899,666...38,908,889
Ensembl chr19:38,899,700...38,908,893 		JBrowse link
G NGEF neuronal guanine nucleotide exchange factor increases expression ISO Glucosamine results in increased expression of NGEF mRNA CTD PMID:17178593 NCBI chr 2:232,878,701...233,013,256
Ensembl chr 2:232,878,701...233,013,256 		JBrowse link
G NGF nerve growth factor multiple interactions ISO Glucosamine inhibits the reaction [IL1B results in increased expression of NGF mRNA] CTD PMID:17109745 NCBI chr 1:115,285,917...115,338,249
Ensembl chr 1:115,285,904...115,338,770 		JBrowse link
G NOS2 nitric oxide synthase 2 multiple interactions
increases expression
decreases expression		 EXP
ISO		 [Glucosamine co-treated with Chondroitin Sulfates co-treated with IL1B protein] results in decreased expression of NOS2 protein; Glucosamine inhibits the reaction [IL1B results in increased expression of NOS2 mRNA]
Glucosamine results in increased expression of NOS2 mRNA
Glucosamine inhibits the reaction [IL1B results in increased expression of NOS2 mRNA]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of NOS2 mRNA]
Glucosamine results in decreased expression of NOS2 mRNA
Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]; Glucosamine inhibits the reaction [Lipopolysaccharides promotes the reaction [RELA protein binds to NOS2 promoter]]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]		 CTD PMID:17109745 PMID:17440993 PMID:17605605 PMID:18077487 PMID:18205790 More... NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529 		JBrowse link
G NR1H4 nuclear receptor subfamily 1 group H member 4 affects expression ISO Glucosamine affects the expression of NR1H4 CTD PMID:19373748 NCBI chr12:100,473,866...100,564,414
Ensembl chr12:100,473,708...100,564,414 		JBrowse link
G NSDHL NAD(P) dependent steroid dehydrogenase-like increases expression ISO Glucosamine results in increased expression of NSDHL mRNA CTD PMID:17178593 NCBI chr  X:152,831,063...152,869,729
Ensembl chr  X:152,830,967...152,869,729 		JBrowse link
G NUCB2 nucleobindin 2 decreases expression ISO Glucosamine results in decreased expression of NUCB2 mRNA CTD PMID:17178593 NCBI chr11:17,276,739...17,349,980
Ensembl chr11:17,208,153...17,349,980 		JBrowse link
G NUF2 NUF2 component of NDC80 kinetochore complex decreases expression ISO Glucosamine results in decreased expression of NUF2 mRNA CTD PMID:17109745 NCBI chr 1:163,321,954...163,355,759
Ensembl chr 1:163,266,576...163,355,764 		JBrowse link
G NUS1 NUS1 dehydrodolichyl diphosphate synthase subunit multiple interactions EXP NUS1 protein inhibits the reaction [Glucosamine inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]]; NUS1 protein inhibits the reaction [Glucosamine results in increased expression of ATF4 mRNA]; NUS1 protein inhibits the reaction [Glucosamine results in increased expression of ATF6 mRNA]; NUS1 protein inhibits the reaction [Glucosamine results in increased expression of DDIT3 mRNA]; NUS1 protein inhibits the reaction [Glucosamine results in increased expression of EIF2AK3 protein]; NUS1 protein inhibits the reaction [Glucosamine results in increased expression of ERN1 mRNA]; NUS1 protein inhibits the reaction [Glucosamine results in increased expression of HSPA5 mRNA]; NUS1 protein inhibits the reaction [Glucosamine results in increased expression of HSPA5 protein]; NUS1 protein inhibits the reaction [Glucosamine results in increased expression of INPP5K mRNA]; NUS1 protein inhibits the reaction [Glucosamine results in increased phosphorylation of EIF2S1 protein]; NUS1 protein inhibits the reaction [Glucosamine results in increased splicing of XBP1 mRNA]; PRKAA1 protein promotes the reaction [NUS1 protein inhibits the reaction [Glucosamine inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]]] CTD PMID:33812996 NCBI chr 6:117,675,469...117,710,727
Ensembl chr 6:117,675,469...117,710,727 		JBrowse link
G OASL2P 2'-5' oligoadenylate synthetase like 2, pseudogene increases expression ISO Glucosamine results in increased expression of OASL2 mRNA CTD PMID:17178593 NCBI chr12:121,053,732...121,059,670
Ensembl chr12:121,053,732...121,059,670 		JBrowse link
G OAT ornithine aminotransferase multiple interactions ISO Glucosamine affects the reaction [IL1B results in decreased expression of OAT mRNA] CTD PMID:17109745 NCBI chr10:124,397,303...124,418,923
Ensembl chr10:124,397,303...124,418,976 		JBrowse link
G OGT O-linked N-acetylglucosamine (GlcNAc) transferase decreases expression ISO Glucosamine results in decreased expression of OGT mRNA CTD PMID:17178593 NCBI chr  X:71,533,104...71,575,892
Ensembl chr  X:71,533,087...71,575,892 		JBrowse link
G ORC2 origin recognition complex subunit 2 decreases expression ISO Glucosamine results in decreased expression of ORC2 mRNA CTD PMID:17178593 NCBI chr 2:200,908,977...200,963,660
Ensembl chr 2:200,908,977...200,963,680 		JBrowse link
G OSM oncostatin M multiple interactions EXP Glucosamine inhibits the reaction [[OSM protein co-treated with IL1B protein] results in decreased methylation of IL1B promoter]; Glucosamine inhibits the reaction [[OSM protein co-treated with IL1B protein] results in increased expression of IL1B mRNA] CTD PMID:21219853 NCBI chr22:30,262,829...30,266,851
Ensembl chr22:30,262,829...30,266,851 		JBrowse link
G OSTN osteocrin multiple interactions
increases expression		 ISO 4-methylumbelliferone 8-carbaldehyde inhibits the reaction [Glucosamine results in increased expression of OSTN mRNA]; 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of OSTN mRNA]; [INS1 protein co-treated with Glucosamine] results in increased expression of OSTN mRNA; ATF6 protein affects the reaction [Glucosamine results in increased expression of OSTN mRNA]; EIF2AK3 protein affects the reaction [Glucosamine results in increased expression of OSTN mRNA]; ERN1 protein affects the reaction [Glucosamine results in increased expression of OSTN mRNA]; GSK2656157 inhibits the reaction [Glucosamine results in increased expression of OSTN mRNA]; OSTN protein affects the reaction [Glucosamine inhibits the reaction [INS1 protein results in increased phosphorylation of AKT1 protein]]; OSTN protein affects the reaction [Glucosamine inhibits the reaction [INS1 protein results in increased uptake of 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose]] CTD PMID:30602124 NCBI chr 3:191,199,241...191,265,615
Ensembl chr 3:191,199,241...191,265,615 		JBrowse link
G OXR1 oxidation resistance 1 decreases expression ISO Glucosamine results in decreased expression of OXR1 mRNA CTD PMID:17178593 NCBI chr 8:106,270,178...106,752,694
Ensembl chr 8:106,270,144...106,752,694 		JBrowse link
G PANK1 pantothenate kinase 1 increases expression ISO Glucosamine results in increased expression of PANK1 mRNA CTD PMID:17178593 NCBI chr10:89,579,495...89,645,242
Ensembl chr10:89,579,497...89,645,242 		JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 increases cleavage
multiple interactions		 EXP Glucosamine results in increased cleavage of PARP1 protein
pepstatin inhibits the reaction [Glucosamine results in increased cleavage of PARP1 protein]		 CTD PMID:16850161 NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154 		JBrowse link
G PDGFA platelet derived growth factor subunit A affects expression
multiple interactions		 ISO Glucosamine affects the expression of PDGFA mRNA
Glucosamine inhibits the reaction [IL1B results in increased expression of PDGFA mRNA]; IL1B affects the reaction [Glucosamine affects the expression of PDGFA mRNA]		 CTD PMID:17109745 NCBI chr 7:497,258...520,700
Ensembl chr 7:497,258...520,296 		JBrowse link
G PDIA4 protein disulfide isomerase family A member 4 decreases expression ISO Glucosamine results in decreased expression of PDIA4 mRNA CTD PMID:17178593 NCBI chr 7:149,003,051...149,028,505
Ensembl chr 7:149,003,062...149,028,662 		JBrowse link
G PDIA6 protein disulfide isomerase family A member 6 decreases expression ISO Glucosamine results in decreased expression of PDIA6 mRNA CTD PMID:17178593 NCBI chr 2:10,783,391...10,837,712
Ensembl chr 2:10,783,391...10,837,977 		JBrowse link
G PDK4 pyruvate dehydrogenase kinase 4 increases expression ISO Glucosamine results in increased expression of PDK4 mRNA CTD PMID:17178593 NCBI chr 7:95,583,499...95,596,516
Ensembl chr 7:95,583,499...95,596,516 		JBrowse link
G PFKP phosphofructokinase, platelet increases expression ISO Glucosamine results in increased expression of PFKP mRNA CTD PMID:17178593 NCBI chr10:3,067,548...3,136,805
Ensembl chr10:3,066,333...3,137,718 		JBrowse link
G PIGA phosphatidylinositol glycan anchor biosynthesis class A decreases expression ISO Glucosamine results in decreased expression of PIGA mRNA CTD PMID:17178593 NCBI chr  X:15,319,451...15,335,554
Ensembl chr  X:15,319,452...15,335,554 		JBrowse link
G PLA2G2A phospholipase A2 group IIA multiple interactions
decreases expression		 ISO Glucosamine inhibits the reaction [IL1B results in increased expression of PLA2G2A mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of PLA2G2A mRNA] CTD PMID:17109745 NCBI chr 1:19,975,431...19,980,434
Ensembl chr 1:19,975,431...19,980,416 		JBrowse link
G PLA2G4A phospholipase A2 group IVA affects expression
multiple interactions		 ISO Glucosamine affects the expression of PLA2G4A mRNA
Glucosamine inhibits the reaction [IL1B results in increased expression of PLA2G4A mRNA]		 CTD PMID:17109745 NCBI chr 1:186,828,949...186,988,981
Ensembl chr 1:186,828,949...186,988,981 		JBrowse link
G PLA2G5 phospholipase A2 group V multiple interactions
decreases expression		 ISO Glucosamine inhibits the reaction [IL1B results in increased expression of PLA2G5 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of PLA2G5 mRNA] CTD PMID:17109745 NCBI chr 1:20,028,408...20,091,911
Ensembl chr 1:20,028,179...20,091,911 		JBrowse link
G PLAT plasminogen activator, tissue type increases expression ISO Glucosamine results in increased expression of PLAT mRNA CTD PMID:17178593 NCBI chr 8:42,174,718...42,207,565
Ensembl chr 8:42,174,718...42,207,709 		JBrowse link
G PLK1 polo like kinase 1 increases expression
decreases expression		 ISO Glucosamine results in increased expression of PLK1 mRNA
Glucosamine results in decreased expression of PLK1 mRNA		 CTD PMID:17109745 PMID:17178593 NCBI chr16:23,678,889...23,690,367
Ensembl chr16:23,677,656...23,690,367 		JBrowse link
G PLPP3 phospholipid phosphatase 3 decreases expression ISO Glucosamine results in decreased expression of PLPP3 mRNA CTD PMID:17109745 NCBI chr 1:56,494,761...56,579,563
Ensembl chr 1:56,494,761...56,645,301 		JBrowse link
G PPARG peroxisome proliferator activated receptor gamma multiple interactions
increases expression		 EXP
ISO		 Glucosamine promotes the reaction [IL1B results in increased expression of PPARG]
Glucosamine results in increased expression of PPARG mRNA		 CTD PMID:15694357 PMID:22089456 NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356 		JBrowse link
G PPARGC1A PPARG coactivator 1 alpha multiple interactions
decreases expression		 EXP
ISO		 4-phenylbutyric acid inhibits the reaction [Glucosamine results in decreased expression of PPARGC1A mRNA]; 4-phenylbutyric acid inhibits the reaction [Glucosamine results in decreased expression of PPARGC1A protein]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of PPARGC1A mRNA]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of PPARGC1A protein]; ursodoxicoltaurine inhibits the reaction [Glucosamine results in decreased expression of PPARGC1A mRNA]; ursodoxicoltaurine inhibits the reaction [Glucosamine results in decreased expression of PPARGC1A protein]
Glucosamine results in decreased expression of PPARGC1A mRNA; Glucosamine results in decreased expression of PPARGC1A protein		 CTD PMID:20165829 NCBI chr 4:23,792,021...24,472,905
Ensembl chr 4:23,755,041...23,904,089 		JBrowse link
G PPM1A protein phosphatase, Mg2+/Mn2+ dependent 1A decreases expression ISO Glucosamine results in decreased expression of PPM1A mRNA CTD PMID:17178593 NCBI chr14:60,245,750...60,299,087
Ensembl chr14:60,245,752...60,299,087 		JBrowse link
G PPP1R15A protein phosphatase 1 regulatory subunit 15A decreases expression ISO Glucosamine results in decreased expression of PPP1R15A mRNA CTD PMID:17178593 NCBI chr19:48,872,421...48,876,058
Ensembl chr19:48,872,212...48,876,059 		JBrowse link
G PRC1 protein regulator of cytokinesis 1 decreases expression ISO Glucosamine results in decreased expression of PRC1 mRNA CTD PMID:17109745 NCBI chr15:90,966,040...90,994,535
Ensembl chr15:90,966,040...90,995,629 		JBrowse link
G PRKAA1 protein kinase AMP-activated catalytic subunit alpha 1 multiple interactions EXP PRKAA1 protein promotes the reaction [Glucosamine inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]]; PRKAA1 protein promotes the reaction [NUS1 protein inhibits the reaction [Glucosamine inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]]] CTD PMID:33812996 NCBI chr 5:40,759,389...40,798,374
Ensembl chr 5:40,759,389...40,798,374 		JBrowse link
G PSME3 proteasome activator subunit 3 decreases expression EXP Glucosamine results in decreased expression of PSME3 CTD PMID:21697645 NCBI chr17:42,833,397...42,843,760
Ensembl chr17:42,824,385...42,843,760 		JBrowse link
G PTGES prostaglandin E synthase multiple interactions EXP [Glucosamine co-treated with Chondroitin Sulfates co-treated with IL1B protein] results in decreased expression of PTGES protein; Glucosamine inhibits the reaction [IL1B results in increased expression of PTGES mRNA] CTD PMID:17605605 PMID:22089456 NCBI chr 9:129,738,349...129,753,042
Ensembl chr 9:129,738,331...129,753,042 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 increases expression
decreases expression
multiple interactions
decreases glycosylation		 EXP
ISO		 Glucosamine analog results in increased expression of PTGS2 protein alternative form
Glucosamine results in decreased expression of PTGS2 mRNA
Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]
Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]; Glucosamine inhibits the reaction [[Lipopolysaccharides results in increased expression of PTGS2 protein] which results in increased secretion of Dinoprostone]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]
Glucosamine results in decreased glycosylation of PTGS2 protein
[Glucosamine co-treated with Chondroitin Sulfates co-treated with IL1B protein] results in decreased expression of PTGS2 protein; Glucosamine inhibits the reaction [IL1B protein results in increased expression of PTGS2 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased expression of PTGS2 protein]		 CTD PMID:12681956 PMID:17440993 PMID:17605605 PMID:18205790 PMID:19656660 More... NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922 		JBrowse link
G PTTG1 PTTG1 regulator of sister chromatid separation, securin decreases expression ISO Glucosamine results in decreased expression of PTTG1 mRNA CTD PMID:17109745 NCBI chr 5:160,421,855...160,428,744
Ensembl chr 5:160,421,855...160,428,739 		JBrowse link
G RAB32 RAB32, member RAS oncogene family increases expression ISO Glucosamine results in increased expression of RAB32 mRNA CTD PMID:17178593 NCBI chr 6:146,543,833...146,554,953
Ensembl chr 6:146,543,833...146,554,953 		JBrowse link
G RACGAP1 Rac GTPase activating protein 1 decreases expression ISO Glucosamine results in decreased expression of RACGAP1 mRNA CTD PMID:17109745 NCBI chr12:49,989,162...50,033,440
Ensembl chr12:49,976,923...50,033,136 		JBrowse link
G RBM39 RNA binding motif protein 39 decreases expression ISO Glucosamine results in decreased expression of RBM39 mRNA CTD PMID:17178593 NCBI chr20:35,701,347...35,742,260
Ensembl chr20:35,701,347...35,742,312 		JBrowse link
G RECQL4 RecQ like helicase 4 increases expression ISO Glucosamine results in increased expression of RECQL4 mRNA CTD PMID:17178593 NCBI chr 8:144,511,288...144,517,833
Ensembl chr 8:144,511,288...144,517,845 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit multiple interactions
decreases activity
increases localization		 EXP
ISO		 Alloxan inhibits the reaction [Glucosamine inhibits the reaction [TNF results in increased phosphorylation of RELA protein]]; Glucosamine analog inhibits the reaction [IL1B results in increased localization of RELA protein]; Glucosamine analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of RELA protein]; Glucosamine inhibits the reaction [Hydrogen Peroxide results in increased expression of and results in increased localization of RELA protein]; Glucosamine inhibits the reaction [IL1B protein results in increased localization of RELA protein]; Glucosamine inhibits the reaction [IL1B results in increased localization of RELA protein]; Glucosamine inhibits the reaction [NFKB1 results in increased degradation of RELA protein]; Glucosamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of RELA protein]; Glucosamine inhibits the reaction [TNF results in increased localization of RELA protein]; Glucosamine inhibits the reaction [TNF results in increased phosphorylation of RELA protein]
Glucosamine results in decreased activity of RELA protein
Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased expression of RELA protein]; Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased localization of RELA protein]; Glucosamine inhibits the reaction [Lipopolysaccharides promotes the reaction [RELA protein binds to NOS2 promoter]]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of RELA mRNA]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased localization of RELA protein]
Glucosamine results in increased localization of RELA protein		 CTD PMID:12681956 PMID:16431966 PMID:16822504 PMID:17238806 PMID:17498959 More... NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090 		JBrowse link
G RELB RELB proto-oncogene, NF-kB subunit multiple interactions ISO Glucosamine inhibits the reaction [IL1B results in increased expression of RELB mRNA] CTD PMID:17109745 NCBI chr19:45,001,464...45,038,192
Ensembl chr19:45,001,461...45,038,192 		JBrowse link
G RHOB ras homolog family member B increases expression ISO Glucosamine results in increased expression of RHOB mRNA CTD PMID:17178593 NCBI chr 2:20,447,074...20,449,440
Ensembl chr 2:20,447,074...20,449,440 		JBrowse link
G RHOC ras homolog family member C decreases expression EXP Glucosamine analog results in decreased expression of RHOC mRNA CTD PMID:16142878 NCBI chr 1:112,701,131...112,707,408
Ensembl chr 1:112,701,127...112,707,434 		JBrowse link
G RND1 Rho family GTPase 1 multiple interactions
decreases expression		 EXP
ISO		 Glucosamine analog inhibits the reaction [TNF results in increased expression of RND1 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of RND1 mRNA]
Glucosamine results in decreased expression of RND1 mRNA		 CTD PMID:17178593 PMID:18173918 NCBI chr12:48,857,145...48,865,870
Ensembl chr12:48,857,145...48,865,870 		JBrowse link
G RPS6 ribosomal protein S6 decreases phosphorylation EXP Glucosamine results in decreased phosphorylation of RPS6 protein CTD PMID:19254699 NCBI chr 9:19,375,715...19,380,236
Ensembl chr 9:19,375,715...19,380,236 		JBrowse link
G RPS6KB1 ribosomal protein S6 kinase B1 decreases phosphorylation EXP Glucosamine results in decreased phosphorylation of RPS6KB1 protein CTD PMID:19254699 NCBI chr17:59,893,121...59,950,574
Ensembl chr17:59,893,046...59,950,574 		JBrowse link
G RUNX2 RUNX family transcription factor 2 increases phosphorylation
increases expression
multiple interactions		 EXP Glucosamine analog results in increased phosphorylation of RUNX2 protein
Glucosamine analog results in increased expression of RUNX2 mRNA
4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [Glucosamine analog results in increased phosphorylation of RUNX2 protein]		 CTD PMID:20458730 NCBI chr 6:45,328,330...45,551,082
Ensembl chr 6:45,328,157...45,664,349 		JBrowse link
G SCD stearoyl-CoA desaturase increases expression ISO Glucosamine results in increased expression of SCD2 mRNA CTD PMID:17178593 NCBI chr10:100,347,233...100,364,826
Ensembl chr10:100,347,233...100,364,826 		JBrowse link
G SDC2 syndecan 2 multiple interactions
decreases expression		 ISO Glucosamine inhibits the reaction [IL1B results in decreased expression of SDC2 mRNA]; IL1B promotes the reaction [Glucosamine results in decreased expression of SDC2 mRNA] CTD PMID:17109745 NCBI chr 8:96,493,813...96,611,790
Ensembl chr 8:96,493,813...96,611,790 		JBrowse link
G SDC4 syndecan 4 multiple interactions
decreases expression		 ISO Glucosamine inhibits the reaction [IL1B results in increased expression of SDC4 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of SDC4 mRNA] CTD PMID:17109745 NCBI chr20:45,325,288...45,348,424
Ensembl chr20:45,325,288...45,348,424 		JBrowse link
G SELENBP1 selenium binding protein 1 decreases expression ISO Glucosamine results in decreased expression of SELENBP1 mRNA CTD PMID:17109745 NCBI chr 1:151,364,304...151,372,705
Ensembl chr 1:151,364,304...151,372,707 		JBrowse link
G SERPINB2 serpin family B member 2 increases expression ISO Glucosamine results in increased expression of SERPINB2 mRNA CTD PMID:17109745 NCBI chr18:63,887,705...63,903,888
Ensembl chr18:63,871,692...63,903,888 		JBrowse link
G SERPINH1 serpin family H member 1 increases expression EXP Glucosamine results in increased expression of SERPINH1 protein CTD PMID:16380481 NCBI chr11:75,562,253...75,572,783
Ensembl chr11:75,562,056...75,572,783 		JBrowse link
G SFRP2 secreted frizzled related protein 2 decreases expression ISO Glucosamine results in decreased expression of SFRP2 mRNA CTD PMID:17109745 NCBI chr 4:153,780,591...153,789,083
Ensembl chr 4:153,780,591...153,789,083 		JBrowse link
G SGK1 serum/glucocorticoid regulated kinase 1 decreases expression ISO Glucosamine results in decreased expression of SGK1 mRNA CTD PMID:17178593 NCBI chr 6:134,169,256...134,318,112
Ensembl chr 6:134,169,248...134,318,112 		JBrowse link
G SHCBP1 SHC binding and spindle associated 1 decreases expression ISO Glucosamine results in decreased expression of SHCBP1 mRNA CTD PMID:17109745 NCBI chr16:46,578,591...46,621,379
Ensembl chr16:46,578,591...46,621,379 		JBrowse link
G SLC17A1 solute carrier family 17 member 1 increases expression ISO Glucosamine results in increased expression of SLC17A1 mRNA CTD PMID:17178593 NCBI chr 6:25,723,743...25,832,052
Ensembl chr 6:25,782,915...25,832,052 		JBrowse link
G SLC23A2 solute carrier family 23 member 2 increases expression ISO Glucosamine results in increased expression of SLC23A2 mRNA CTD PMID:17109745 NCBI chr20:4,852,358...5,010,313
Ensembl chr20:4,852,356...5,010,293 		JBrowse link
G SLC2A2 solute carrier family 2 member 2 decreases expression ISO Glucosamine results in decreased expression of SLC2A2 mRNA CTD PMID:11893929 NCBI chr 3:170,996,347...171,026,720
Ensembl chr 3:170,996,347...171,026,743 		JBrowse link
G SLC2A4 solute carrier family 2 member 4 multiple interactions
decreases expression
increases uptake		 EXP
ISO		 4-phenylbutyric acid inhibits the reaction [Glucosamine results in decreased expression of SLC2A4 mRNA]; 4-phenylbutyric acid inhibits the reaction [Glucosamine results in decreased expression of SLC2A4 protein]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of SLC2A4 mRNA]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of SLC2A4 protein]; ursodoxicoltaurine inhibits the reaction [Glucosamine results in decreased expression of SLC2A4 mRNA]; ursodoxicoltaurine inhibits the reaction [Glucosamine results in decreased expression of SLC2A4 protein]
Glucosamine results in decreased expression of SLC2A4 mRNA; Glucosamine results in decreased expression of SLC2A4 protein
SLC2A4 protein results in increased uptake of Glucosamine
Glucosamine inhibits the reaction [SLC2A4 protein results in increased uptake of Glucose]; Glucose inhibits the reaction [SLC2A4 protein results in increased uptake of Glucosamine]		 CTD PMID:19373748 PMID:20165829 NCBI chr17:7,281,718...7,288,257
Ensembl chr17:7,281,718...7,288,257 		JBrowse link
G SLC2A6 solute carrier family 2 member 6 decreases expression ISO Glucosamine results in decreased expression of SLC2A6 mRNA CTD PMID:17178593 NCBI chr 9:133,471,094...133,479,099
Ensembl chr 9:133,471,094...133,479,127 		JBrowse link
G SLC37A4 solute carrier family 37 member 4 increases expression ISO Glucosamine results in increased expression of SLC37A4 mRNA CTD PMID:17178593 NCBI chr11:119,024,112...119,030,877
Ensembl chr11:119,023,751...119,030,906 		JBrowse link
G SLC4A4 solute carrier family 4 member 4 decreases expression ISO Glucosamine results in decreased expression of SLC4A4 mRNA CTD PMID:17109745 NCBI chr 4:71,062,660...71,572,083
Ensembl chr 4:71,062,667...71,572,087 		JBrowse link
G SLC7A8 solute carrier family 7 member 8 increases expression
multiple interactions		 ISO Glucosamine results in increased expression of SLC7A8 mRNA
Glucosamine inhibits the reaction [IL1B results in increased expression of SLC7A8 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of SLC7A8 mRNA]		 CTD PMID:17109745 NCBI chr14:23,125,295...23,183,660
Ensembl chr14:23,125,295...23,183,674 		JBrowse link
G SMAD2 SMAD family member 2 multiple interactions
increases phosphorylation		 EXP 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [Glucosamine analog results in increased phosphorylation of SMAD2 protein] CTD PMID:20458730 NCBI chr18:47,808,957...47,930,872
Ensembl chr18:47,808,957...47,931,146 		JBrowse link
G SMPD3 sphingomyelin phosphodiesterase 3 decreases expression ISO Glucosamine results in decreased expression of SMPD3 mRNA CTD PMID:17109745 NCBI chr16:68,358,327...68,448,508
Ensembl chr16:68,358,327...68,448,508 		JBrowse link
G SOX4 SRY-box transcription factor 4 multiple interactions
decreases expression		 ISO Glucosamine inhibits the reaction [IL1B results in decreased expression of SOX4 mRNA]
Glucosamine results in decreased expression of SOX4 mRNA		 CTD PMID:17109745 NCBI chr 6:21,593,751...21,598,619
Ensembl chr 6:21,593,751...21,598,619 		JBrowse link
G SRSF3 serine and arginine rich splicing factor 3 decreases expression ISO Glucosamine results in decreased expression of SRSF3 mRNA CTD PMID:17178593 NCBI chr 6:36,594,362...36,605,600
Ensembl chr 6:36,594,353...36,605,600 		JBrowse link
G ST6GAL1 ST6 beta-galactoside alpha-2,6-sialyltransferase 1 increases expression ISO Glucosamine results in increased expression of ST6GAL1 mRNA CTD PMID:17178593 NCBI chr 3:186,930,526...187,078,553
Ensembl chr 3:186,930,325...187,078,553 		JBrowse link
G STAT1 signal transducer and activator of transcription 1 multiple interactions EXP Glucosamine inhibits the reaction [IFNG results in increased localization of STAT1 protein modified form]; Glucosamine inhibits the reaction [IFNG results in increased phosphorylation of and results in increased localization of STAT1 protein] CTD PMID:16431966 PMID:17238806 NCBI chr 2:190,969,149...191,014,171
Ensembl chr 2:190,908,460...191,020,960 		JBrowse link
G TACC3 transforming acidic coiled-coil containing protein 3 decreases expression ISO Glucosamine results in decreased expression of TACC3 mRNA CTD PMID:17109745 NCBI chr 4:1,721,521...1,745,171
Ensembl chr 4:1,712,858...1,745,171 		JBrowse link
G TGFA transforming growth factor alpha multiple interactions ISO [Glucose co-treated with Glucosamine] results in increased expression of TGFA protein; Glucosamine promotes the reaction [Glucose results in increased expression of TGFA mRNA] CTD PMID:1518840 NCBI chr 2:70,447,284...70,553,826
Ensembl chr 2:70,447,284...70,554,193 		JBrowse link
G TGFB1 transforming growth factor beta 1 increases expression ISO Glucosamine analog results in increased expression of TGFB1 mRNA CTD PMID:21466783 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922 		JBrowse link
G TGFBR1 transforming growth factor beta receptor 1 multiple interactions
increases expression		 EXP 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [Glucosamine analog results in increased expression of TGFBR1 protein] CTD PMID:20458730 NCBI chr 9:99,103,647...99,154,192
Ensembl chr 9:99,104,038...99,154,192 		JBrowse link
G THBS4 thrombospondin 4 multiple interactions
decreases expression		 ISO Glucosamine inhibits the reaction [IL1B results in decreased expression of THBS4 mRNA]; IL1B promotes the reaction [Glucosamine results in decreased expression of THBS4 mRNA] CTD PMID:17109745 NCBI chr 5:79,991,332...80,083,287
Ensembl chr 5:79,991,311...80,083,287 		JBrowse link
G TIMP1 TIMP metallopeptidase inhibitor 1 multiple interactions
increases expression		 ISO Glucosamine inhibits the reaction [IL1B results in increased expression of TIMP1 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of TIMP1 mRNA] CTD PMID:17109745 NCBI chr  X:47,582,436...47,586,789
Ensembl chr  X:47,582,408...47,586,789 		JBrowse link
G TIMP2 TIMP metallopeptidase inhibitor 2 affects expression
multiple interactions		 ISO Glucosamine affects the expression of TIMP2 mRNA
Glucosamine inhibits the reaction [IL1B results in decreased expression of TIMP2 mRNA]		 CTD PMID:17109745 NCBI chr17:78,852,977...78,925,387
Ensembl chr17:78,852,977...78,925,387 		JBrowse link
G TIMP3 TIMP metallopeptidase inhibitor 3 multiple interactions
increases expression		 EXP
ISO		 [Glucosamine co-treated with Chondroitin Sulfates co-treated with IL1B protein] results in increased expression of TIMP3 mRNA
Glucosamine results in increased expression of TIMP3 mRNA
Glucosamine inhibits the reaction [IL1B results in decreased expression of TIMP3 mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of TIMP3 mRNA]		 CTD PMID:17109745 PMID:17605605 NCBI chr22:32,801,705...32,863,041
Ensembl chr22:32,801,705...32,863,041 		JBrowse link
G TINAG tubulointerstitial nephritis antigen increases expression ISO Glucosamine results in increased expression of TINAG mRNA CTD PMID:17178593 NCBI chr 6:54,307,862...54,390,142
Ensembl chr 6:54,307,859...54,390,142 		JBrowse link
G TK1 thymidine kinase 1 decreases expression ISO Glucosamine results in decreased expression of TK1 mRNA CTD PMID:17109745 NCBI chr17:78,174,079...78,187,204
Ensembl chr17:78,174,091...78,187,233 		JBrowse link
G TLR1 toll like receptor 1 increases expression ISO Glucosamine results in increased expression of TLR1 mRNA CTD PMID:17178593 NCBI chr 4:38,787,569...38,805,644
Ensembl chr 4:38,790,677...38,856,817 		JBrowse link
G TNF tumor necrosis factor decreases secretion
multiple interactions
decreases expression		 ISO
EXP		 Glucosamine results in decreased secretion of TNF protein
Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]
Glucosamine analog results in decreased expression of TNF mRNA; Glucosamine results in decreased expression of TNF mRNA
Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased secretion of TNF protein]; Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]
[Glucosamine co-treated with Chondroitin Sulfates] results in decreased expression of TNF; Alloxan inhibits the reaction [Glucosamine inhibits the reaction [TNF results in increased phosphorylation of RELA protein]]; Glucosamine analog inhibits the reaction [TNF results in increased expression of CUL2 mRNA]; Glucosamine analog inhibits the reaction [TNF results in increased expression of CXCL8 mRNA]; Glucosamine analog inhibits the reaction [TNF results in increased expression of GSPT1 mRNA]; Glucosamine analog inhibits the reaction [TNF results in increased expression of IL6 mRNA]; Glucosamine analog inhibits the reaction [TNF results in increased expression of RND1 mRNA]; Glucosamine analog inhibits the reaction [TNF results in increased expression of TNFRSF1A mRNA]; Glucosamine analog inhibits the reaction [TNF results in increased expression of TNFRSF1B mRNA]; Glucosamine analog inhibits the reaction [TNF results in increased expression of TRAF6 mRNA]; Glucosamine inhibits the reaction [[IL6 co-treated with TNF] results in increased expression of ICAM1 protein]; Glucosamine inhibits the reaction [IFNG promotes the reaction [TNF results in increased expression of ICAM1 protein]]; Glucosamine inhibits the reaction [IL1B promotes the reaction [TNF results in increased expression of ICAM1 protein]]; Glucosamine inhibits the reaction [TNF promotes the reaction [IFNG results in increased expression of ICAM1 protein]]; Glucosamine inhibits the reaction [TNF promotes the reaction [IL1B results in increased expression of ICAM1 protein]]; Glucosamine inhibits the reaction [TNF results in increased expression of CCL2 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of CCL2 protein]; Glucosamine inhibits the reaction [TNF results in increased expression of CUL2 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of CXCL8 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of GSPT1 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of ICAM1 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of ICAM1 protein]; Glucosamine inhibits the reaction [TNF results in increased expression of IL6 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of RND1 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of TNFRSF1A mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of TNFRSF1B mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of TRAF6 mRNA]; Glucosamine inhibits the reaction [TNF results in increased localization of RELA protein]; Glucosamine inhibits the reaction [TNF results in increased phosphorylation of RELA protein]		 CTD PMID:14507305 PMID:16431966 PMID:16445576 PMID:16822504 PMID:17238806 More... NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TNFAIP6 TNF alpha induced protein 6 multiple interactions
decreases expression		 ISO Glucosamine inhibits the reaction [IL1B results in increased expression of TNFAIP6 mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of TNFAIP6 mRNA] CTD PMID:17109745 NCBI chr 2:151,357,592...151,381,340
Ensembl chr 2:151,357,592...151,380,046 		JBrowse link
G TNFRSF11B TNF receptor superfamily member 11b multiple interactions EXP [Chondroitin Sulfates co-treated with Glucosamine co-treated with Cholecalciferol] results in increased expression of TNFRSF11B mRNA; [Chondroitin Sulfates co-treated with Glucosamine co-treated with Cholecalciferol] results in increased expression of TNFRSF11B protein; [Chondroitin Sulfates co-treated with Glucosamine] results in increased expression of TNFRSF11B mRNA; [Chondroitin Sulfates co-treated with Glucosamine] results in increased expression of TNFRSF11B protein CTD PMID:17996099 NCBI chr 8:118,923,557...118,951,885
Ensembl chr 8:118,923,557...118,951,885 		JBrowse link
G TNFRSF1A TNF receptor superfamily member 1A multiple interactions EXP Glucosamine analog inhibits the reaction [TNF results in increased expression of TNFRSF1A mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of TNFRSF1A mRNA] CTD PMID:18173918 NCBI chr12:6,328,771...6,342,076
Ensembl chr12:6,328,757...6,342,114 		JBrowse link
G TNFRSF1B TNF receptor superfamily member 1B multiple interactions EXP Glucosamine analog inhibits the reaction [TNF results in increased expression of TNFRSF1B mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of TNFRSF1B mRNA] CTD PMID:18173918 NCBI chr 1:12,166,991...12,209,220
Ensembl chr 1:12,166,991...12,209,228 		JBrowse link
G TNFSF11 TNF superfamily member 11 multiple interactions
increases expression		 EXP [Chondroitin Sulfates co-treated with Glucosamine] inhibits the reaction [Cholecalciferol results in increased expression of TNFSF11 mRNA]; Chondroitin Sulfates inhibits the reaction [Glucosamine results in increased expression of TNFSF11 mRNA] CTD PMID:17996099 NCBI chr13:42,562,736...42,608,013
Ensembl chr13:42,562,736...42,608,013 		JBrowse link
G TNK2 tyrosine kinase non receptor 2 multiple interactions ISO Glucosamine inhibits the reaction [IL1B results in increased expression of TNK2 mRNA] CTD PMID:17109745 NCBI chr 3:195,863,364...195,908,551
Ensembl chr 3:195,863,364...195,911,945 		JBrowse link
G TOP2A DNA topoisomerase II alpha decreases expression ISO Glucosamine results in decreased expression of TOP2A mRNA CTD PMID:17109745 NCBI chr17:40,388,525...40,417,896
Ensembl chr17:40,388,525...40,417,896 		JBrowse link
G TRAF6 TNF receptor associated factor 6 multiple interactions EXP Glucosamine analog inhibits the reaction [TNF results in increased expression of TRAF6 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of TRAF6 mRNA] CTD PMID:18173918 NCBI chr11:36,483,769...36,510,272
Ensembl chr11:36,483,769...36,510,272 		JBrowse link
G TRPV4 transient receptor potential cation channel subfamily V member 4 increases expression ISO Glucosamine results in increased expression of TRPV4 mRNA CTD PMID:17178593 NCBI chr12:109,783,087...109,833,398
Ensembl chr12:109,783,087...109,833,406 		JBrowse link
G TXN thioredoxin decreases expression ISO Glucosamine results in decreased expression of TXN1 protein CTD PMID:17178593 NCBI chr 9:110,243,810...110,256,507
Ensembl chr 9:110,243,810...110,256,507 		JBrowse link
G TXNIP thioredoxin interacting protein increases expression
multiple interactions		 ISO Glucosamine results in increased expression of TXNIP protein
Glucosamine results in increased expression of TXNIP mRNA; Glucosamine results in increased expression of TXNIP protein
Glucosamine promotes the reaction [TXNIP results in increased abundance of Reactive Oxygen Species]; TXNIP promotes the reaction [Glucosamine results in increased expression of LAMB1 mRNA]; TXNIP promotes the reaction [Glucosamine results in increased expression of LAMC1 mRNA]		 CTD PMID:17178593 NCBI chr 1:145,992,435...145,996,579
Ensembl chr 1:145,992,435...145,996,579 		JBrowse link
G UCP2 uncoupling protein 2 decreases expression ISO Glucosamine results in decreased expression of UCP2 mRNA CTD PMID:11893929 NCBI chr11:73,974,672...73,983,202
Ensembl chr11:73,974,672...73,982,843 		JBrowse link
G UQCRH ubiquinol-cytochrome c reductase hinge protein increases expression ISO Glucosamine results in increased expression of UQCRH mRNA CTD PMID:17178593 NCBI chr 1:46,303,698...46,316,776
Ensembl chr 1:46,303,698...46,316,776 		JBrowse link
G VAMP1 vesicle associated membrane protein 1 increases expression ISO Glucosamine results in increased expression of VAMP1 mRNA CTD PMID:17109745 NCBI chr12:6,462,237...6,470,677
Ensembl chr12:6,462,237...6,470,677 		JBrowse link
G VCAN versican multiple interactions
decreases expression		 ISO Glucosamine inhibits the reaction [IL1B results in increased expression of VCAN mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of VCAN mRNA] CTD PMID:17109745 NCBI chr 5:83,471,744...83,582,302
Ensembl chr 5:83,471,618...83,582,303 		JBrowse link
G VEGFA vascular endothelial growth factor A multiple interactions
increases expression
decreases expression		 EXP
ISO		 Glucosamine inhibits the reaction [Oxygen deficiency results in increased expression of VEGFA protein]
Glucosamine results in increased expression of VEGFA protein
Glucosamine results in decreased expression of VEGFA protein		 CTD PMID:16324875 PMID:19254699 NCBI chr 6:43,770,211...43,786,487
Ensembl chr 6:43,770,184...43,786,487 		JBrowse link
G VEGFD vascular endothelial growth factor D increases expression
decreases expression		 ISO Glucosamine results in increased expression of VEGFD mRNA
Glucosamine results in decreased expression of VEGFD mRNA		 CTD PMID:17109745 PMID:17178593 NCBI chr  X:15,345,596...15,384,413
Ensembl chr  X:15,345,596...15,384,413 		JBrowse link
G VNN1 vanin 1 increases expression ISO Glucosamine results in increased expression of VNN1 mRNA CTD PMID:17178593 NCBI chr 6:132,680,849...132,714,055
Ensembl chr 6:132,680,849...132,714,055 		JBrowse link
G XBP1 X-box binding protein 1 multiple interactions
increases splicing
increases expression
decreases splicing		 EXP
ISO		 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of XBP1 mRNA]; NUS1 protein inhibits the reaction [Glucosamine results in increased splicing of XBP1 mRNA]; ursodoxicoltaurine inhibits the reaction [Glucosamine results in increased expression of XBP1 mRNA]
Glucosamine results in increased expression of XBP1 protein alternative form
4-methylumbelliferone 8-carbaldehyde affects the reaction [Glucosamine results in increased expression of XBP1 protein alternative form]; 4-methylumbelliferone 8-carbaldehyde inhibits the reaction [Glucosamine results in increased splicing of XBP1 mRNA]; 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of XBP1 protein alternative form]; 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased splicing of XBP1 mRNA]; ERN1 protein affects the reaction [Glucosamine results in increased splicing of XBP1 mRNA]
4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of XBP1 mRNA]; ursodoxicoltaurine inhibits the reaction [Glucosamine results in increased expression of XBP1 mRNA]
Glucosamine results in decreased splicing of XBP1 mRNA		 CTD PMID:19383982 PMID:20165829 PMID:30602124 PMID:33812996 NCBI chr22:28,794,560...28,800,569
Ensembl chr22:28,794,555...28,800,597 		JBrowse link
G XDH xanthine dehydrogenase multiple interactions ISO [XDH protein co-treated with Hypoxanthine] inhibits the reaction [Glucosamine results in increased abundance of Proteoglycans]; [XDH protein co-treated with Hypoxanthine] inhibits the reaction [Glucosamine results in increased expression of B3GAT3 mRNA] CTD PMID:11801247 NCBI chr 2:31,334,321...31,414,742
Ensembl chr 2:31,334,321...31,414,742 		JBrowse link
G ZNF467 zinc finger protein 467 increases expression ISO Glucosamine results in increased expression of ZFP467 mRNA CTD PMID:17178593 NCBI chr 7:149,764,182...149,776,530
Ensembl chr 7:149,764,182...149,773,588 		JBrowse link
calycosin-7-O-beta-D-glucoside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAX BCL2 associated X, apoptosis regulator increases expression
multiple interactions		 EXP
ISO		 calycosin-7-O-beta-D-glucoside results in increased expression of BAX mRNA; calycosin-7-O-beta-D-glucoside results in increased expression of BAX protein
TXN protein affects the reaction [calycosin-7-O-beta-D-glucoside results in increased expression of BAX mRNA]; TXN protein affects the reaction [calycosin-7-O-beta-D-glucoside results in increased expression of BAX protein]		 CTD PMID:36812960 NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798 		JBrowse link
G BCL2 BCL2 apoptosis regulator decreases expression
multiple interactions		 EXP
ISO		 calycosin-7-O-beta-D-glucoside results in decreased expression of BCL2 mRNA; calycosin-7-O-beta-D-glucoside results in decreased expression of BCL2 protein
TXN protein affects the reaction [calycosin-7-O-beta-D-glucoside results in decreased expression of BCL2 mRNA]; TXN protein affects the reaction [calycosin-7-O-beta-D-glucoside results in decreased expression of BCL2 protein]		 CTD PMID:36812960 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128 		JBrowse link
G CASP3 caspase 3 increases expression
increases cleavage
multiple interactions		 EXP
ISO		 calycosin-7-O-beta-D-glucoside results in increased expression of CASP3 mRNA
calycosin-7-O-beta-D-glucoside results in increased cleavage of CASP3 protein
TXN protein affects the reaction [calycosin-7-O-beta-D-glucoside results in increased cleavage of CASP3 protein]; TXN protein affects the reaction [calycosin-7-O-beta-D-glucoside results in increased expression of CASP3 mRNA]		 CTD PMID:36812960 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062 		JBrowse link
G CAT catalase decreases expression EXP
ISO		 calycosin-7-O-beta-D-glucoside results in decreased expression of CAT protein CTD PMID:36812960 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060 		JBrowse link
G EPO erythropoietin increases expression EXP calycosin-7-O-beta-D-glucoside results in increased expression of EPO mRNA CTD PMID:21309574 PMID:37348668 NCBI chr 7:100,720,468...100,723,700
Ensembl chr 7:100,720,468...100,723,700 		JBrowse link
G GPT glutamic--pyruvic transaminase decreases expression ISO calycosin-7-O-beta-D-glucoside results in decreased expression of GPT protein CTD PMID:36812960 NCBI chr 8:144,503,068...144,507,172
Ensembl chr 8:144,502,973...144,507,174 		JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha multiple interactions
increases expression		 EXP calycosin-7-O-beta-D-glucoside results in decreased degradation of and results in increased expression of HIF1A protein modified form; calycosin-7-O-beta-D-glucoside results in increased expression of and results in decreased degradation of HIF1A protein
calycosin-7-O-beta-D-glucoside results in increased expression of HIF1A mRNA; calycosin-7-O-beta-D-glucoside results in increased expression of HIF1A protein		 CTD PMID:21309574 PMID:37348668 NCBI chr14:61,695,513...61,748,258
Ensembl chr14:61,695,513...61,748,259 		JBrowse link
G TXN thioredoxin multiple interactions
decreases expression		 EXP
ISO		 TXN protein affects the reaction [calycosin-7-O-beta-D-glucoside results in decreased expression of BCL2 mRNA]; TXN protein affects the reaction [calycosin-7-O-beta-D-glucoside results in decreased expression of BCL2 protein]; TXN protein affects the reaction [calycosin-7-O-beta-D-glucoside results in increased cleavage of CASP3 protein]; TXN protein affects the reaction [calycosin-7-O-beta-D-glucoside results in increased expression of BAX mRNA]; TXN protein affects the reaction [calycosin-7-O-beta-D-glucoside results in increased expression of BAX protein]; TXN protein affects the reaction [calycosin-7-O-beta-D-glucoside results in increased expression of CASP3 mRNA]
calycosin-7-O-beta-D-glucoside results in decreased expression of TXN protein
calycosin-7-O-beta-D-glucoside results in decreased expression of TXN mRNA; calycosin-7-O-beta-D-glucoside results in decreased expression of TXN protein		 CTD PMID:36812960 NCBI chr 9:110,243,810...110,256,507
Ensembl chr 9:110,243,810...110,256,507 		JBrowse link
D-glucopyranose 6-phosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FBP1 fructose-bisphosphatase 1 multiple interactions ISO [Enzyme Inhibitors results in decreased activity of FBP1 protein] which results in decreased abundance of Glucose-6-Phosphate CTD PMID:31974165 NCBI chr 9:94,603,133...94,640,263
Ensembl chr 9:94,603,133...94,640,249 		JBrowse link
G G6PC1 glucose-6-phosphatase catalytic subunit 1 multiple interactions ISO [Fluoxetine results in decreased expression of G6PC1 protein] which results in increased abundance of Glucose-6-Phosphate CTD PMID:33179799 NCBI chr17:42,900,799...42,914,438
Ensembl chr17:42,900,797...42,914,438 		JBrowse link
G G6PC2 glucose-6-phosphatase catalytic subunit 2 increases hydrolysis EXP G6PC2 protein results in increased hydrolysis of Glucose-6-Phosphate CTD PMID:14722102 NCBI chr 2:168,901,291...168,910,000
Ensembl chr 2:168,901,291...168,910,000 		JBrowse link
G GPD2 glycerol-3-phosphate dehydrogenase 2 multiple interactions ISO GPD2 protein inhibits the reaction [Dihydroxyacetone results in increased abundance of Glucose-6-Phosphate]; GPD2 protein inhibits the reaction [Glucose results in increased abundance of Glucose-6-Phosphate]; GPD2 protein inhibits the reaction [Glycerol results in increased abundance of Glucose-6-Phosphate] CTD PMID:31974165 NCBI chr 2:156,400,281...156,586,403
Ensembl chr 2:156,435,290...156,613,735 		JBrowse link
G NR4A1 nuclear receptor subfamily 4 group A member 1 multiple interactions ISO [Glycerol co-treated with Succinic Acid co-treated with Glucose-6-Phosphate co-treated with Pantothenic Acid co-treated with Niacinamide] results in increased expression of NR4A1 mRNA CTD PMID:20505214 NCBI chr12:52,022,832...52,059,503
Ensembl chr12:52,022,832...52,059,507 		JBrowse link
G PFKFB1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 multiple interactions
increases abundance		 ISO PFKFB1 gene mutant form inhibits the reaction [Metformin results in decreased abundance of Glucose-6-Phosphate metabolite]
PFKFB1 gene mutant form results in increased abundance of Glucose-6-Phosphate		 CTD PMID:31974165 NCBI chr  X:54,932,961...54,998,789
Ensembl chr  X:54,932,961...54,998,534 		JBrowse link
G PRKAA1 protein kinase AMP-activated catalytic subunit alpha 1 multiple interactions ISO [[PRKAA1 gene co-treated with PRKAA2 gene] affects the susceptibility to 4-hydroxy-3-(4-(2-hydroxyphenyl)phenyl)-6-oxo-7H-thieno(2,3-b)pyridine-5-carbonitrile] which results in increased abundance of Glucose-6-Phosphate; [[PRKAA1 gene mutant form co-treated with PRKAA2 gene mutant form] affects the susceptibility to [Glucose co-treated with S 4048]] which results in increased abundance of Glucose-6-Phosphate; [[PRKAA1 gene mutant form co-treated with PRKAA2 gene mutant form] affects the susceptibility to Metformin] which results in increased abundance of Glucose-6-Phosphate CTD PMID:31974165 NCBI chr 5:40,759,389...40,798,374
Ensembl chr 5:40,759,389...40,798,374 		JBrowse link
G PRKAA2 protein kinase AMP-activated catalytic subunit alpha 2 multiple interactions ISO [[PRKAA1 gene co-treated with PRKAA2 gene] affects the susceptibility to 4-hydroxy-3-(4-(2-hydroxyphenyl)phenyl)-6-oxo-7H-thieno(2,3-b)pyridine-5-carbonitrile] which results in increased abundance of Glucose-6-Phosphate; [[PRKAA1 gene mutant form co-treated with PRKAA2 gene mutant form] affects the susceptibility to [Glucose co-treated with S 4048]] which results in increased abundance of Glucose-6-Phosphate; [[PRKAA1 gene mutant form co-treated with PRKAA2 gene mutant form] affects the susceptibility to Metformin] which results in increased abundance of Glucose-6-Phosphate CTD PMID:31974165 NCBI chr 1:56,645,314...56,715,335
Ensembl chr 1:56,645,314...56,715,335 		JBrowse link
daidzein 7-O-beta-D-glucoside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACHE acetylcholinesterase (Yt blood group) increases expression
multiple interactions		 ISO daidzin results in increased expression of ACHE mRNA
4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline inhibits the reaction [daidzin results in increased expression of ACHE mRNA]; 4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline inhibits the reaction [daidzin results in increased expression of and results in increased activity of ACHE protein]; daidzin results in increased expression of and results in increased activity of ACHE protein		 CTD PMID:31034797 NCBI chr 7:100,889,994...100,896,994
Ensembl chr 7:100,889,994...100,896,974 		JBrowse link
G ACSL3 acyl-CoA synthetase long chain family member 3 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of ACSL3 mRNA CTD PMID:27424125 NCBI chr 2:222,861,036...222,944,639
Ensembl chr 2:222,860,942...222,944,639 		JBrowse link
G ALDH1A2 aldehyde dehydrogenase 1 family member A2 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of ALDH1A2 mRNA CTD PMID:27424125 NCBI chr15:57,953,429...58,065,711
Ensembl chr15:57,953,424...58,497,866 		JBrowse link
G ALDH2 aldehyde dehydrogenase 2 family member multiple interactions EXP daidzin inhibits the reaction [ALDH2 protein results in increased hydrolysis of 4-nitrophenyl acetate]; daidzin inhibits the reaction [ALDH2 protein results in increased oxidation of propionaldehyde] CTD PMID:21349255 NCBI chr12:111,766,933...111,817,532
Ensembl chr12:111,766,887...111,817,532 		JBrowse link
G ANPEP alanyl aminopeptidase, membrane multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of ANPEP mRNA CTD PMID:27424125 NCBI chr15:89,784,895...89,814,852
Ensembl chr15:89,784,895...89,815,401 		JBrowse link
G ATOH8 atonal bHLH transcription factor 8 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of ATOH8 mRNA CTD PMID:27424125 NCBI chr 2:85,753,991...85,791,383
Ensembl chr 2:85,751,344...85,791,383 		JBrowse link
G BCKDK branched chain keto acid dehydrogenase kinase multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of BCKDK mRNA CTD PMID:27424125 NCBI chr16:31,108,386...31,117,640
Ensembl chr16:31,106,107...31,112,791 		JBrowse link
G BDNF brain derived neurotrophic factor multiple interactions ISO daidzin inhibits the reaction [Pentylenetetrazole results in decreased expression of BDNF protein] CTD PMID:32450180 NCBI chr11:27,654,893...27,722,030
Ensembl chr11:27,654,893...27,722,058 		JBrowse link
G BPGM bisphosphoglycerate mutase multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of BPGM mRNA CTD PMID:27424125 NCBI chr 7:134,646,853...134,679,816
Ensembl chr 7:134,646,811...134,679,816 		JBrowse link
G CABP5 calcium binding protein 5 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of CABP5 mRNA CTD PMID:27424125 NCBI chr19:48,029,383...48,044,079
Ensembl chr19:48,029,383...48,044,079 		JBrowse link
G CACYBP calcyclin binding protein multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of CACYBP mRNA CTD PMID:27424125 NCBI chr 1:174,999,435...175,012,027
Ensembl chr 1:174,999,163...175,012,027 		JBrowse link
G CASP8AP2 caspase 8 associated protein 2 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of CASP8AP2 mRNA CTD PMID:27424125 NCBI chr 6:89,829,880...89,874,436
Ensembl chr 6:89,829,894...89,874,436 		JBrowse link
G CAT catalase multiple interactions ISO daidzin inhibits the reaction [Pentylenetetrazole results in decreased activity of CAT protein] CTD PMID:32450180 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060 		JBrowse link
G CD200R1 CD200 receptor 1 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of CD200R1 mRNA CTD PMID:27424125 NCBI chr 3:112,921,205...112,975,103
Ensembl chr 3:112,921,205...112,975,103 		JBrowse link
G CFAP251 cilia and flagella associated protein 251 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of CFAP251 mRNA CTD PMID:27424125 NCBI chr12:121,918,592...122,003,919
Ensembl chr12:121,918,592...122,003,927 		JBrowse link
G CYBRD1 cytochrome b reductase 1 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of CYBRD1 mRNA CTD PMID:27424125 NCBI chr 2:171,522,233...171,558,129
Ensembl chr 2:171,522,247...171,558,129 		JBrowse link
G CYP11A1 cytochrome P450 family 11 subfamily A member 1 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of CYP11A1 mRNA CTD PMID:28964809 NCBI chr15:74,337,762...74,367,646
Ensembl chr15:74,337,759...74,367,646 		JBrowse link
G DENND2D DENN domain containing 2D multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of DENND2D mRNA CTD PMID:27424125 NCBI chr 1:111,185,969...111,204,578
Ensembl chr 1:111,185,969...111,204,535 		JBrowse link
G DNMT1 DNA methyltransferase 1 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in increased expression of DNMT1 mRNA CTD PMID:28964809 NCBI chr19:10,133,346...10,194,953
Ensembl chr19:10,133,342...10,231,286 		JBrowse link
G DNMT3A DNA methyltransferase 3 alpha multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in increased expression of DNMT3A mRNA CTD PMID:28964809 NCBI chr 2:25,227,874...25,342,590
Ensembl chr 2:25,227,855...25,342,590 		JBrowse link
G DPP9 dipeptidyl peptidase 9 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of DPP9 mRNA CTD PMID:27424125 NCBI chr19:4,675,227...4,723,842
Ensembl chr19:4,674,341...4,724,673 		JBrowse link
G EDRF1 erythroid differentiation regulatory factor 1 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of EDRF1 mRNA CTD PMID:27424125 NCBI chr10:125,719,709...125,764,139
Ensembl chr10:125,719,515...125,764,143 		JBrowse link
G EFHD1 EF-hand domain family member D1 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of EFHD1 mRNA CTD PMID:27424125 NCBI chr 2:232,606,057...232,682,776
Ensembl chr 2:232,606,057...232,682,776 		JBrowse link
G ESR2 estrogen receptor 2 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in increased expression of ESR2 mRNA CTD PMID:28964809 NCBI chr14:64,226,707...64,338,613
Ensembl chr14:64,084,232...64,338,112 		JBrowse link
G FAM171A2 family with sequence similarity 171 member A2 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of FAM171A2 mRNA CTD PMID:27424125 NCBI chr17:44,353,215...44,363,853
Ensembl chr17:44,353,215...44,363,853 		JBrowse link
G FAM180A family with sequence similarity 180 member A multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of FAM180A mRNA CTD PMID:27424125 NCBI chr 7:135,729,592...135,748,813
Ensembl chr 7:135,728,348...135,748,813 		JBrowse link
G FAM210B family with sequence similarity 210 member B multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of FAM210B mRNA CTD PMID:27424125 NCBI chr20:56,358,974...56,368,663
Ensembl chr20:56,358,974...56,368,663 		JBrowse link
G FAM241B family with sequence similarity 241 member B multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of FAM241B mRNA CTD PMID:27424125 NCBI chr10:69,630,247...69,633,596
Ensembl chr10:69,630,247...69,633,596 		JBrowse link
G FGD6 FYVE, RhoGEF and PH domain containing 6 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of FGD6 mRNA CTD PMID:27424125 NCBI chr12:95,076,749...95,217,467
Ensembl chr12:95,076,749...95,217,482 		JBrowse link
G FHL2 four and a half LIM domains 2 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of FHL2 mRNA CTD PMID:27424125 NCBI chr 2:105,357,712...105,438,529
Ensembl chr 2:105,357,712...105,438,513 		JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit increases expression EXP daidzin results in increased expression of FOS mRNA CTD PMID:17142977 NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,282,230 		JBrowse link
G GALNT15 polypeptide N-acetylgalactosaminyltransferase 15 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of GALNT15 mRNA CTD PMID:27424125 NCBI chr 3:16,174,680...16,248,224
Ensembl chr 3:16,174,680...16,231,992 		JBrowse link
G GNG5 G protein subunit gamma 5 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of GNG5 mRNA CTD PMID:27424125 NCBI chr 1:84,498,325...84,506,581
Ensembl chr 1:84,498,323...84,506,581 		JBrowse link
G HIPK4 homeodomain interacting protein kinase 4 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of HIPK4 mRNA CTD PMID:27424125 NCBI chr19:40,379,271...40,390,181
Ensembl chr19:40,379,271...40,390,181 		JBrowse link
G HMCN1 hemicentin 1 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of HMCN1 mRNA CTD PMID:27424125 NCBI chr 1:185,734,391...186,190,949
Ensembl chr 1:185,734,391...186,190,949 		JBrowse link
G HMOX1 heme oxygenase 1 multiple interactions ISO daidzin inhibits the reaction [Pentylenetetrazole results in decreased expression of HMOX1 protein] CTD PMID:32450180 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214 		JBrowse link
G HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of HSD3B1 mRNA CTD PMID:28964809 NCBI chr 1:119,507,203...119,515,058
Ensembl chr 1:119,507,198...119,515,054 		JBrowse link
G IL6R interleukin 6 receptor multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of IL6R mRNA CTD PMID:27424125 NCBI chr 1:154,405,343...154,469,450
Ensembl chr 1:154,405,193...154,469,450 		JBrowse link
G ISG20L2 interferon stimulated exonuclease gene 20 like 2 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of ISG20L2 mRNA CTD PMID:27424125 NCBI chr 1:156,721,891...156,728,766
Ensembl chr 1:156,721,891...156,728,766 		JBrowse link
G KDM5A lysine demethylase 5A multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of KDM5A mRNA CTD PMID:27424125 NCBI chr12:280,057...389,320
Ensembl chr12:280,057...389,320 		JBrowse link
G KITLG KIT ligand multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of KITLG mRNA CTD PMID:27424125 NCBI chr12:88,492,793...88,580,471
Ensembl chr12:88,492,793...88,580,851 		JBrowse link
G KNSTRN kinetochore localized astrin (SPAG5) binding protein multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of KNSTRN mRNA CTD PMID:27424125 NCBI chr15:40,382,721...40,394,288
Ensembl chr15:40,382,721...40,394,288 		JBrowse link
G LDLRAP1 low density lipoprotein receptor adaptor protein 1 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of LDLRAP1 mRNA CTD PMID:27424125 NCBI chr 1:25,543,606...25,590,400
Ensembl chr 1:25,543,606...25,568,886 		JBrowse link
G LMOD1 leiomodin 1 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of LMOD1 mRNA CTD PMID:27424125 NCBI chr 1:201,896,456...201,946,548
Ensembl chr 1:201,896,456...201,946,548 		JBrowse link
G LRG1 leucine rich alpha-2-glycoprotein 1 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of LRG1 mRNA CTD PMID:27424125 NCBI chr19:4,536,402...4,540,036
Ensembl chr19:4,536,402...4,540,036 		JBrowse link
G LSR lipolysis stimulated lipoprotein receptor multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of LSR mRNA CTD PMID:27424125 NCBI chr19:35,249,002...35,267,964
Ensembl chr19:35,248,330...35,267,964 		JBrowse link
G MRPL33 mitochondrial ribosomal protein L33 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of MRPL33 mRNA CTD PMID:27424125 NCBI chr 2:27,771,719...27,779,733
Ensembl chr 2:27,771,717...27,988,087 		JBrowse link
G MTMR11 myotubularin related protein 11 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of MTMR11 mRNA CTD PMID:27424125 NCBI chr 1:149,928,651...149,936,879
Ensembl chr 1:149,928,651...149,936,879 		JBrowse link
G MYOF myoferlin multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of MYOF mRNA CTD PMID:27424125 NCBI chr10:93,306,429...93,482,334
Ensembl chr10:93,306,429...93,482,334 		JBrowse link
G NEFH neurofilament heavy chain increases expression ISO daidzin results in increased expression of NEFH mRNA; daidzin results in increased expression of NEFH protein CTD PMID:31034797 NCBI chr22:29,480,218...29,491,390
Ensembl chr22:29,480,218...29,491,390 		JBrowse link
G NEFL neurofilament light chain increases expression ISO daidzin results in increased expression of NEFL mRNA; daidzin results in increased expression of NEFL protein CTD PMID:31034797 NCBI chr 8:24,950,955...24,956,612
Ensembl chr 8:24,950,955...24,956,721 		JBrowse link
G NR4A1 nuclear receptor subfamily 4 group A member 1 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of NR4A1 mRNA CTD PMID:27424125 NCBI chr12:52,022,832...52,059,503
Ensembl chr12:52,022,832...52,059,507 		JBrowse link
G NR5A1 nuclear receptor subfamily 5 group A member 1 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of NR5A1 mRNA; [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of NR5A1 protein; [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in increased methylation of NR5A1 promoter; decitabine inhibits the reaction [[Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of NR5A1 mRNA] CTD PMID:28964809 NCBI chr 9:124,481,236...124,507,399
Ensembl chr 9:124,481,236...124,507,420 		JBrowse link
G PGR progesterone receptor increases expression EXP daidzin results in increased expression of PGR protein CTD PMID:17142977 NCBI chr11:101,029,624...101,129,813
Ensembl chr11:101,029,624...101,129,813 		JBrowse link
G PRIMA1 proline rich membrane anchor 1 increases expression
multiple interactions		 ISO daidzin results in increased expression of PRIMA1 mRNA
4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline inhibits the reaction [daidzin results in increased expression of PRIMA1 mRNA]		 CTD PMID:31034797 NCBI chr14:93,718,298...93,788,994
Ensembl chr14:93,718,298...93,788,485 		JBrowse link
G PRKACA protein kinase cAMP-activated catalytic subunit alpha multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of PRKACA mRNA CTD PMID:27424125 NCBI chr19:14,091,688...14,117,762
Ensembl chr19:14,091,688...14,118,084 		JBrowse link
G PRPF40A pre-mRNA processing factor 40 homolog A multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of PRPF40A mRNA CTD PMID:27424125 NCBI chr 2:152,651,732...152,718,019
Ensembl chr 2:152,651,593...152,718,012 		JBrowse link
G PSPC1 paraspeckle component 1 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of PSPC1 mRNA CTD PMID:27424125 NCBI chr13:19,671,205...19,782,945
Ensembl chr13:19,674,752...19,783,019 		JBrowse link
G PTH1R parathyroid hormone 1 receptor multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of PTH1R mRNA CTD PMID:27424125 NCBI chr 3:46,877,721...46,903,799
Ensembl chr 3:46,877,721...46,903,799 		JBrowse link
G RASSF5 Ras association domain family member 5 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of RASSF5 mRNA CTD PMID:27424125 NCBI chr 1:206,507,531...206,589,448
Ensembl chr 1:206,507,531...206,589,448 		JBrowse link
G RGS22 regulator of G protein signaling 22 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of RGS22 mRNA CTD PMID:27424125 NCBI chr 8:99,960,936...100,106,049
Ensembl chr 8:99,960,936...100,131,268 		JBrowse link
G S1PR3 sphingosine-1-phosphate receptor 3 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of S1PR3 mRNA CTD PMID:27424125 NCBI chr 9:88,990,863...89,005,155
Ensembl chr 9:88,990,863...89,005,155 		JBrowse link
G SELPLG selectin P ligand multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of SELPLG mRNA CTD PMID:27424125 NCBI chr12:108,621,895...108,633,894
Ensembl chr12:108,621,895...108,633,894 		JBrowse link
G SIGLEC10 sialic acid binding Ig like lectin 10 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of SIGLEC10 mRNA CTD PMID:27424125 NCBI chr19:51,410,020...51,417,642
Ensembl chr19:51,410,020...51,417,803 		JBrowse link
G SLC16A1 solute carrier family 16 member 1 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of SLC16A1 mRNA CTD PMID:27424125 NCBI chr 1:112,911,847...112,956,196
Ensembl chr 1:112,911,847...112,957,593 		JBrowse link
G SNX30 sorting nexin family member 30 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of SNX30 mRNA CTD PMID:27424125 NCBI chr 9:112,749,723...112,885,769
Ensembl chr 9:112,750,760...112,881,671 		JBrowse link
G SSC5D scavenger receptor cysteine rich family member with 5 domains multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of SSC5D mRNA CTD PMID:27424125 NCBI chr19:55,488,436...55,519,099
Ensembl chr19:55,488,404...55,519,099 		JBrowse link
G STAR steroidogenic acute regulatory protein multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of STAR mRNA; [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of STAR protein CTD PMID:28964809 NCBI chr 8:38,142,700...38,150,952
Ensembl chr 8:38,142,700...38,150,992 		JBrowse link
G STYXL1 serine/threonine/tyrosine interacting like 1 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of STYXL1 mRNA CTD PMID:27424125 NCBI chr 7:75,996,337...76,048,000
Ensembl chr 7:75,996,338...76,048,004 		JBrowse link
G SUMO1 small ubiquitin like modifier 1 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of SUMO1 mRNA CTD PMID:27424125 NCBI chr 2:202,206,171...202,238,597
Ensembl chr 2:202,206,182...202,238,599 		JBrowse link
G TC2N tandem C2 domains, nuclear multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of TC2N mRNA CTD PMID:27424125 NCBI chr14:91,779,746...91,867,536
Ensembl chr14:91,779,746...91,867,536 		JBrowse link
G TP53I11 tumor protein p53 inducible protein 11 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of TP53I11 mRNA CTD PMID:27424125 NCBI chr11:44,932,348...44,951,306
Ensembl chr11:44,885,903...44,951,306 		JBrowse link
G VCPIP1 valosin containing protein interacting protein 1 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of VCPIP1 mRNA CTD PMID:27424125 NCBI chr 8:66,628,487...66,667,231
Ensembl chr 8:66,628,487...66,667,231 		JBrowse link
G VEGFA vascular endothelial growth factor A multiple interactions ISO daidzin inhibits the reaction [Pentylenetetrazole results in increased expression of VEGFA protein] CTD PMID:32450180 NCBI chr 6:43,770,211...43,786,487
Ensembl chr 6:43,770,184...43,786,487 		JBrowse link
etoposide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 affects response to substance
increases expression
multiple interactions		 EXP ABCB1 exon polymorphism affects the susceptibility to Etoposide
Etoposide results in increased expression of ABCB1 mRNA; Etoposide results in increased expression of ABCB1 protein
[[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [Celecoxib results in decreased expression of ABCB1] which results in increased susceptibility to Etoposide		 CTD PMID:12969965 PMID:15239124 PMID:19047049 PMID:19562670 PMID:27570640 More... NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323 		JBrowse link
G ABCC1 ATP binding cassette subfamily C member 1 (ABCC1 blood group) affects response to substance
multiple interactions
increases expression
decreases uptake
decreases response to substance		 EXP
ISO		 ABCC1 protein affects the susceptibility to Etoposide
Glucose inhibits the reaction [Sodium Azide inhibits the reaction [ABCC1 protein results in decreased uptake of Etoposide]]; Sodium Azide inhibits the reaction [ABCC1 protein results in decreased uptake of Etoposide]; Verapamil inhibits the reaction [ABCC1 protein results in decreased susceptibility to Etoposide]; Verapamil inhibits the reaction [ABCC1 protein results in decreased uptake of Etoposide]
Etoposide results in increased expression of ABCC1 mRNA
ABCC1 protein results in decreased susceptibility to Etoposide; ABCC1 results in decreased susceptibility to Etoposide
[GCLC protein co-treated with GCLM protein] promotes the reaction [ABCC1 protein results in decreased susceptibility to Etoposide]; [MYCN protein affects the expression of ABCC1 mRNA] which affects the susceptibility to Etoposide; GSTP1 protein promotes the reaction [ABCC1 protein results in decreased susceptibility to Etoposide]; hesperetin inhibits the reaction [ABCC1 protein results in decreased susceptibility to Etoposide]; naringenin inhibits the reaction [ABCC1 protein results in decreased susceptibility to Etoposide]; resveratrol inhibits the reaction [ABCC1 protein results in decreased susceptibility to Etoposide]; Silymarin inhibits the reaction [ABCC1 protein results in decreased susceptibility to Etoposide]; Tocopherols inhibits the reaction [ABCC1 protein affects the export of Etoposide]; verlukast inhibits the reaction [ABCC1 protein results in decreased susceptibility to Etoposide]		 CTD PMID:7954421 PMID:8968083 PMID:9334814 PMID:10348353 PMID:10856430 More... NCBI chr16:15,949,143...16,143,053
Ensembl chr16:15,949,138...16,143,257 		JBrowse link
G ABCC2 ATP binding cassette subfamily C member 2 affects transport
multiple interactions		 EXP ABCC2 protein affects the transport of Etoposide
Probenecid promotes the reaction [ABCC2 protein affects the transport of Etoposide]		 CTD PMID:15751272 PMID:15849751 NCBI chr10:99,782,640...99,852,594
Ensembl chr10:99,782,640...99,852,594 		JBrowse link
G ABCC3 ATP binding cassette subfamily C member 3 decreases response to substance EXP ABCC3 protein results in decreased susceptibility to Etoposide CTD PMID:15884115 NCBI chr17:50,634,881...50,692,253
Ensembl chr17:50,634,777...50,692,253 		JBrowse link
G ABCG2 ATP binding cassette subfamily G member 2 (JR blood group) multiple interactions EXP [ERBB2 results in increased expression of ABCG2] which results in decreased susceptibility to Etoposide; ABCG2 mutant form inhibits the reaction [ERBB2 results in decreased susceptibility to Etoposide] CTD PMID:21712253 NCBI chr 4:88,090,264...88,231,626
Ensembl chr 4:88,090,150...88,231,628 		JBrowse link
G ABHD4 abhydrolase domain containing 4, N-acyl phospholipase B increases expression ISO Etoposide results in increased expression of ABHD4 mRNA CTD PMID:25270620 NCBI chr14:22,598,300...22,612,963
Ensembl chr14:22,598,290...22,612,963 		JBrowse link
G ABRA actin binding Rho activating protein increases expression EXP Etoposide results in increased expression of ABRA mRNA CTD PMID:29397400 NCBI chr 8:106,759,483...106,770,244
Ensembl chr 8:106,759,483...106,770,244 		JBrowse link
G ACADM acyl-CoA dehydrogenase medium chain affects response to substance EXP ACADM protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 1:75,724,709...75,763,679
Ensembl chr 1:75,724,431...75,787,575 		JBrowse link
G ACE2 angiotensin converting enzyme 2 increases expression
decreases expression		 EXP
ISO		 Etoposide results in increased expression of ACE2 mRNA
Etoposide results in decreased expression of ACE2 mRNA		 CTD PMID:29397400 PMID:32808185 NCBI chr  X:15,518,197...15,607,211
Ensembl chr  X:15,494,566...15,607,236 		JBrowse link
G ACO1 aconitase 1 increases expression ISO Etoposide results in increased expression of ACO1 mRNA CTD PMID:25270620 NCBI chr 9:32,384,643...32,454,769
Ensembl chr 9:32,384,603...32,454,769 		JBrowse link
G ACSL3 acyl-CoA synthetase long chain family member 3 affects response to substance EXP ACSL3 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 2:222,861,036...222,944,639
Ensembl chr 2:222,860,942...222,944,639 		JBrowse link
G ACTA1 actin alpha 1, skeletal muscle decreases expression EXP Etoposide results in decreased expression of ACTA1 mRNA CTD PMID:29397400 NCBI chr 1:229,431,245...229,434,094
Ensembl chr 1:229,430,365...229,434,104 		JBrowse link
G AGRN agrin increases expression EXP Etoposide results in increased expression of AGRN mRNA CTD PMID:17374387 NCBI chr 1:1,020,120...1,056,116
Ensembl chr 1:1,020,120...1,056,118 		JBrowse link
G AHCYL1 adenosylhomocysteinase like 1 affects response to substance EXP AHCYL1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 1:109,984,765...110,023,742
Ensembl chr 1:109,984,765...110,023,742 		JBrowse link
G AHI1 Abelson helper integration site 1 increases expression EXP Etoposide results in increased expression of AHI1 protein alternative form CTD PMID:19379585 NCBI chr 6:135,283,532...135,497,740
Ensembl chr 6:135,283,407...135,498,434 		JBrowse link
G AKAP12 A-kinase anchoring protein 12 affects response to substance EXP AKAP12 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 6:151,239,967...151,358,559
Ensembl chr 6:151,239,967...151,358,559 		JBrowse link
G AKT1 AKT serine/threonine kinase 1 increases response to substance
increases phosphorylation
multiple interactions		 EXP AKT1 protein modified form results in increased susceptibility to Etoposide
Etoposide results in increased phosphorylation of AKT1 protein
Etoposide results in increased phosphorylation of and results in increased activity of AKT1 protein; NFKB1 protein affects the reaction [Etoposide results in increased phosphorylation of AKT1 protein]; pepstatin inhibits the reaction [AKT1 protein modified form results in increased susceptibility to Etoposide]; PTEN protein inhibits the reaction [Etoposide results in increased phosphorylation of and results in increased activity of AKT1 protein]		 CTD PMID:17699715 PMID:17935137 PMID:23396362 PMID:27769712 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,759 		JBrowse link
G ALAD aminolevulinate dehydratase multiple interactions EXP [Cyclophosphamide co-treated with Carmustine co-treated with Etoposide] results in decreased activity of ALAD protein CTD PMID:19162187 NCBI chr 9:113,386,312...113,401,284
Ensembl chr 9:113,386,312...113,401,290 		JBrowse link
G ALAS1 5'-aminolevulinate synthase 1 increases expression ISO Etoposide results in increased expression of ALAS1 mRNA CTD PMID:25270620 NCBI chr 3:52,198,083...52,214,327
Ensembl chr 3:52,198,086...52,214,327 		JBrowse link
G ALDH1A1 aldehyde dehydrogenase 1 family member A1 multiple interactions
increases expression		 EXP FTL protein affects the reaction [Etoposide results in increased expression of ALDH1A1 protein]
Etoposide results in increased expression of ALDH1A1 mRNA; Etoposide results in increased expression of ALDH1A1 protein		 CTD PMID:33969609 NCBI chr 9:72,900,671...72,953,053
Ensembl chr 9:72,900,671...73,080,442 		JBrowse link
G ALDH3A1 aldehyde dehydrogenase 3 family member A1 affects response to substance EXP ALDH3A1 protein affects the susceptibility to Etoposide CTD PMID:15905174 NCBI chr17:19,737,984...19,748,298
Ensembl chr17:19,737,984...19,748,943 		JBrowse link
G ALDOC aldolase, fructose-bisphosphate C affects response to substance
multiple interactions		 EXP
ISO		 ALDOC protein affects the susceptibility to Etoposide
[Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of ALDOC protein		 CTD PMID:16217747 PMID:29733421 NCBI chr17:28,573,120...28,576,895
Ensembl chr17:28,573,115...28,576,948 		JBrowse link
G ALPG alkaline phosphatase, germ cell affects response to substance EXP ALPG protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 2:232,406,844...232,410,714
Ensembl chr 2:232,406,844...232,410,714 		JBrowse link
G ALPP alkaline phosphatase, placental affects response to substance EXP ALPP protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 2:232,378,751...232,382,889
Ensembl chr 2:232,378,724...232,382,889 		JBrowse link
G ANK1 ankyrin 1 increases expression EXP Etoposide results in increased expression of ANK1 mRNA CTD PMID:29397400 NCBI chr 8:41,653,225...41,896,741
Ensembl chr 8:41,653,220...41,896,741 		JBrowse link
G ANKRD10 ankyrin repeat domain 10 decreases expression EXP Etoposide results in decreased expression of ANKRD10 mRNA CTD PMID:21527772 NCBI chr13:110,878,540...110,915,069
Ensembl chr13:110,878,540...110,915,069 		JBrowse link
G ANKRD27 ankyrin repeat domain 27 decreases expression ISO Etoposide results in decreased expression of ANKRD27 mRNA CTD PMID:25270620 NCBI chr19:32,597,006...32,675,180
Ensembl chr19:32,597,006...32,676,597 		JBrowse link
G ANKRD28 ankyrin repeat domain 28 affects response to substance EXP ANKRD28 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 3:15,667,236...15,859,814
Ensembl chr 3:15,667,236...15,859,771 		JBrowse link
G ANXA4 annexin A4 increases expression EXP Etoposide results in increased expression of ANXA4 mRNA CTD PMID:17374387 NCBI chr 2:69,643,808...69,827,112
Ensembl chr 2:69,644,425...69,827,112 		JBrowse link
G ANXA7 annexin A7 multiple interactions ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of ANXA7 protein CTD PMID:29733421 NCBI chr10:73,375,101...73,414,058
Ensembl chr10:73,375,101...73,414,076 		JBrowse link
G APAF1 apoptotic peptidase activating factor 1 increases expression ISO Etoposide results in increased expression of APAF1 mRNA CTD PMID:25270620 NCBI chr12:98,645,290...98,735,433
Ensembl chr12:98,645,149...98,735,433 		JBrowse link
G APEX1 apurinic/apyrimidinic endodeoxyribonuclease 1 decreases response to substance EXP APEX1 protein results in decreased susceptibility to Etoposide CTD PMID:20856196 NCBI chr14:20,455,226...20,457,767
Ensembl chr14:20,455,191...20,457,772 		JBrowse link
G APLP1 amyloid beta precursor like protein 1 decreases expression ISO Etoposide results in decreased expression of APLP1 mRNA CTD PMID:25270620 NCBI chr19:35,868,574...35,879,792
Ensembl chr19:35,867,899...35,879,792 		JBrowse link
G APOBEC3C apolipoprotein B mRNA editing enzyme catalytic subunit 3C affects response to substance EXP APOBEC3C protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr22:39,014,257...39,020,352
Ensembl chr22:39,014,257...39,020,352 		JBrowse link
G APOL2 apolipoprotein L2 increases expression ISO Etoposide results in increased expression of APOL8 mRNA CTD PMID:25270620 NCBI chr22:36,226,209...36,239,954
Ensembl chr22:36,226,209...36,239,954 		JBrowse link
G AQP1 aquaporin 1 (Colton blood group) decreases expression ISO Etoposide results in decreased expression of AQP1 mRNA CTD PMID:25270620 NCBI chr 7:30,911,853...30,925,516
Ensembl chr 7:30,911,853...30,925,517 		JBrowse link
G AR androgen receptor multiple interactions
increases degradation		 EXP calpain inhibitor 2 inhibits the reaction [Etoposide results in increased degradation of AR protein]; CAST inhibits the reaction [Etoposide results in increased degradation of AR protein]; Etoposide inhibits the reaction [Androgens results in increased activity of AR protein]; Etoposide inhibits the reaction [Metribolone results in increased activity of AR protein] CTD PMID:18726991 PMID:28377212 PMID:30818834 NCBI chr  X:67,544,021...67,730,619
Ensembl chr  X:67,544,021...67,730,619 		JBrowse link
G AREG amphiregulin increases expression
decreases expression		 EXP
ISO		 Etoposide results in increased expression of AREG mRNA; Etoposide results in increased expression of AREG protein
Etoposide results in decreased expression of AREG mRNA		 CTD PMID:15228094 PMID:25270620 NCBI chr 4:74,445,136...74,455,005
Ensembl chr 4:74,445,136...74,455,005 		JBrowse link
G ARG2 arginase 2 decreases expression EXP Etoposide results in decreased expression of ARG2 mRNA CTD PMID:29397400 NCBI chr14:67,619,920...67,651,708
Ensembl chr14:67,619,920...67,651,708 		JBrowse link
G ARHGDIB Rho GDP dissociation inhibitor beta increases expression EXP Etoposide results in increased expression of ARHGDIB mRNA CTD PMID:21527772 NCBI chr12:14,942,015...14,961,601
Ensembl chr12:14,942,031...14,961,728 		JBrowse link
G ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 increases response to substance ISO ARIH1 mutant form results in increased susceptibility to Etoposide CTD PMID:25624349 NCBI chr15:72,474,330...72,602,987
Ensembl chr15:72,474,330...72,602,987 		JBrowse link
G ARL6IP5 ADP ribosylation factor like GTPase 6 interacting protein 5 increases response to substance
decreases expression		 EXP ARL6IP5 protein results in increased susceptibility to Etoposide
Etoposide results in decreased expression of ARL6IP5		 CTD PMID:19492242 NCBI chr 3:69,084,937...69,106,092
Ensembl chr 3:69,084,937...69,106,092 		JBrowse link
G ARNT aryl hydrocarbon receptor nuclear translocator multiple interactions EXP ARNT protein affects the reaction [Etoposide results in increased expression of FTL protein] CTD PMID:33969609 NCBI chr 1:150,809,713...150,876,599
Ensembl chr 1:150,809,713...150,876,708 		JBrowse link
G ARSA arylsulfatase A decreases expression ISO Etoposide results in decreased expression of ARSA mRNA CTD PMID:25270620 NCBI chr22:50,622,754...50,628,152
Ensembl chr22:50,622,754...50,628,173 		JBrowse link
G ASAH1 N-acylsphingosine amidohydrolase 1 affects response to substance EXP ASAH1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 8:18,055,992...18,084,961
Ensembl chr 8:18,055,992...18,084,998 		JBrowse link
G ATF2 activating transcription factor 2 multiple interactions EXP Etoposide results in increased phosphorylation of and results in increased activity of ATF2 protein CTD PMID:12663670 NCBI chr 2:175,072,259...175,168,203
Ensembl chr 2:175,072,250...175,168,382 		JBrowse link
G ATF4 activating transcription factor 4 decreases expression ISO Etoposide results in decreased expression of ATF4 mRNA CTD PMID:25270620 NCBI chr22:39,520,559...39,522,686
Ensembl chr22:39,519,695...39,522,683 		JBrowse link
G ATM ATM serine/threonine kinase multiple interactions
increases phosphorylation		 ISO
EXP		 Etoposide results in increased phosphorylation of and results in increased activity of ATM protein
Etoposide results in increased phosphorylation of ATM protein
Etoposide results in increased phosphorylation of and affects the localization of ATM protein; pifithrin inhibits the reaction [Etoposide results in increased phosphorylation of and affects the localization of ATM protein]		 CTD PMID:22242153 PMID:26259609 PMID:37451322 NCBI chr11:108,223,067...108,369,102
Ensembl chr11:108,222,804...108,369,102 		JBrowse link
G ATP13A4 ATPase 13A4 decreases expression ISO Etoposide results in decreased expression of ATP13A4 mRNA CTD PMID:25270620 NCBI chr 3:193,398,967...193,593,119
Ensembl chr 3:193,398,967...193,593,111 		JBrowse link
G ATP1A1 ATPase Na+/K+ transporting subunit alpha 1 affects response to substance EXP ATP1A1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 1:116,373,244...116,404,774
Ensembl chr 1:116,372,668...116,410,261 		JBrowse link
G ATP1A2 ATPase Na+/K+ transporting subunit alpha 2 decreases expression EXP Etoposide results in decreased expression of ATP1A2 mRNA CTD PMID:29397400 NCBI chr 1:160,115,759...160,143,591
Ensembl chr 1:160,115,759...160,143,591 		JBrowse link
G ATP1B4 ATPase Na+/K+ transporting family member beta 4 increases expression EXP Etoposide results in increased expression of ATP1B4 mRNA CTD PMID:29397400 NCBI chr  X:120,362,089...120,383,237
Ensembl chr  X:120,362,085...120,383,249 		JBrowse link
G ATP5ME ATP synthase membrane subunit e multiple interactions ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in increased expression of ATP5ME protein CTD PMID:29733421 NCBI chr 4:672,436...674,276
Ensembl chr 4:672,436...674,330 		JBrowse link
G ATP5PO ATP synthase peripheral stalk subunit OSCP decreases expression ISO Etoposide results in decreased expression of ATP5PO protein CTD PMID:29733421 NCBI chr21:33,903,453...33,915,804
Ensembl chr21:33,903,453...33,915,814 		JBrowse link
G ATP6V0A4 ATPase H+ transporting V0 subunit a4 affects response to substance EXP ATP6V0A4 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 7:138,706,294...138,798,196
Ensembl chr 7:138,706,294...138,799,560 		JBrowse link
G ATP6V1A ATPase H+ transporting V1 subunit A decreases expression
multiple interactions		 ISO Etoposide results in decreased expression of ATP6V1A protein
[Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of ATP6V1A protein		 CTD PMID:29733421 NCBI chr 3:113,747,035...113,812,056
Ensembl chr 3:113,746,770...113,812,056 		JBrowse link
G ATP7A ATPase copper transporting alpha decreases response to substance EXP ATP7A protein results in decreased susceptibility to Etoposide CTD PMID:17510416 NCBI chr  X:77,910,693...78,050,395
Ensembl chr  X:77,910,690...78,050,395 		JBrowse link
G ATR ATR serine/threonine kinase increases phosphorylation ISO Etoposide results in increased phosphorylation of ATR protein CTD PMID:22242153 NCBI chr 3:142,449,235...142,578,733
Ensembl chr 3:142,449,007...142,578,733 		JBrowse link
G ATXN1 ataxin 1 decreases expression EXP Etoposide results in decreased expression of ATXN1 mRNA CTD PMID:24211769 NCBI chr 6:16,299,112...16,761,460
Ensembl chr 6:16,299,112...16,761,491 		JBrowse link
G AURKA aurora kinase A decreases expression ISO Etoposide results in decreased expression of AURKA mRNA CTD PMID:25270620 NCBI chr20:56,369,390...56,392,215
Ensembl chr20:56,369,389...56,392,337 		JBrowse link
G AVPI1 arginine vasopressin induced 1 affects response to substance EXP AVPI1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr10:97,677,424...97,687,241
Ensembl chr10:97,677,424...97,687,241 		JBrowse link
G AVPR1A arginine vasopressin receptor 1A increases expression EXP Etoposide results in increased expression of AVPR1A mRNA CTD PMID:29397400 NCBI chr12:63,142,759...63,151,201
Ensembl chr12:63,142,759...63,151,201 		JBrowse link
G AXL AXL receptor tyrosine kinase increases expression EXP Etoposide results in increased expression of AXL mRNA CTD PMID:21527772 NCBI chr19:41,219,223...41,261,766
Ensembl chr19:41,219,223...41,261,766 		JBrowse link
G BACE2 beta-secretase 2 affects response to substance EXP BACE2 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr21:41,168,160...41,282,530
Ensembl chr21:41,167,801...41,282,530 		JBrowse link
G BAG2 BAG cochaperone 2 affects response to substance EXP BAG2 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 6:57,172,326...57,189,833
Ensembl chr 6:57,172,326...57,189,833 		JBrowse link
G BAK1 BCL2 antagonist/killer 1 increases activity
increases response to substance
affects response to substance
multiple interactions
affects expression		 EXP
ISO		 Etoposide results in increased activity of BAK1 protein
BAK1 protein results in increased susceptibility to Etoposide
BAK1 protein affects the susceptibility to Etoposide
nimesulide inhibits the reaction [Etoposide results in increased activity of BAK1 protein]
Etoposide affects the expression of BAK1 protein		 CTD PMID:15215046 PMID:16077961 PMID:17688235 PMID:21745461 NCBI chr 6:33,572,552...33,580,276
Ensembl chr 6:33,572,547...33,580,293 		JBrowse link
G BAMBI BMP and activin membrane bound inhibitor affects response to substance EXP BAMBI protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr10:28,677,521...28,682,932
Ensembl chr10:28,677,510...28,682,932 		JBrowse link
G BAX BCL2 associated X, apoptosis regulator multiple interactions
increases expression
decreases folding
affects response to substance		 EXP
ISO		 [ABT-737 co-treated with Etoposide] affects the folding of and results in increased activity of BAX protein; [Cisplatin co-treated with Etoposide] affects the localization of BAX protein; [Doxorubicin co-treated with Vincristine co-treated with Etoposide co-treated with Mitotane] results in decreased expression of BAX protein; [IL4 protein co-treated with VCAM1 protein] inhibits the reaction [Etoposide results in decreased folding of BAX protein]; [RASSF1 co-treated with Etoposide] affects the folding of and results in increased activity of BAX protein; [trigonelline co-treated with Etoposide] results in increased expression of BAX protein; [VCAM1 protein co-treated with IL4 protein] inhibits the reaction [Etoposide inhibits the reaction [BAX protein binds to BCL2L1 protein]]; Etoposide inhibits the reaction [BAX protein binds to BCL2L1 protein]; Etoposide results in increased activity of and affects the localization of BAX protein; Etoposide results in increased cleavage of and results in increased expression of BAX protein; Nicotine inhibits the reaction [[Cisplatin co-treated with Etoposide] affects the localization of BAX protein]; nimesulide inhibits the reaction [Etoposide results in increased activity of and affects the localization of BAX protein]
Etoposide results in increased expression of BAX mRNA; Etoposide results in increased expression of BAX protein
BAX protein affects the susceptibility to Etoposide		 CTD PMID:9815696 PMID:10620629 PMID:15131059 PMID:16077961 PMID:16120219 More... NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798 		JBrowse link
G BBC3 BCL2 binding component 3 increases expression
multiple interactions
affects response to substance		 EXP
ISO		 Etoposide results in increased expression of BBC3 mRNA; Etoposide results in increased expression of BBC3 protein
entinostat promotes the reaction [Etoposide results in increased expression of BBC3 protein]; Etoposide promotes the reaction [entinostat results in increased expression of BBC3 protein]; Etoposide promotes the reaction [trichostatin A results in increased expression of BBC3 protein]; Etoposide promotes the reaction [UF010 compound results in increased expression of BBC3 protein]; TP53 protein modified form inhibits the reaction [Etoposide results in increased expression of BBC3 protein]; trichostatin A promotes the reaction [Etoposide results in increased expression of BBC3 protein]; UF010 compound promotes the reaction [Etoposide results in increased expression of BBC3 protein]
BBC3 protein affects the susceptibility to Etoposide		 CTD PMID:20477944 PMID:21801448 PMID:25699604 PMID:37956312 NCBI chr19:47,220,824...47,232,860
Ensembl chr19:47,220,822...47,232,766 		JBrowse link
G BCL2 BCL2 apoptosis regulator multiple interactions
decreases expression		 EXP
ISO		 [Doxorubicin co-treated with Vincristine co-treated with Etoposide co-treated with Mitotane] results in decreased expression of BCL2 protein; [Etoposide co-treated with Ciprofloxacin] results in decreased expression of BCL2 protein; [trigonelline co-treated with Etoposide] results in decreased expression of BCL2 protein; BCL2 protein inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; BCL2 protein inhibits the reaction [Etoposide results in increased degradation of PARP1 protein]; BCL2 protein results in decreased susceptibility to [Cisplatin co-treated with Etoposide]
Etoposide results in decreased expression of BCL2 mRNA; Etoposide results in decreased expression of BCL2 protein
[G(M3) Ganglioside results in increased expression of BCL2 protein] which results in decreased susceptibility to Etoposide; BCL2 protein affects the reaction [[Etoposide results in increased activity of GSK3B protein] which results in increased activity of CASP3 protein]; Lithium Chloride inhibits the reaction [Etoposide results in decreased expression of BCL2 mRNA]; Lithium Chloride inhibits the reaction [Etoposide results in decreased expression of BCL2 protein]		 CTD PMID:8840993 PMID:9815696 PMID:12063570 PMID:15917659 PMID:16571667 More... NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128 		JBrowse link
G BCL2L1 BCL2 like 1 multiple interactions
affects expression
decreases response to substance		 EXP [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of BCL2L1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of BCL2L1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [VCAM1 protein co-treated with IL4 protein] inhibits the reaction [Etoposide inhibits the reaction [BAX protein binds to BCL2L1 protein]]; BCL2L1 protein inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; BCL2L1 protein inhibits the reaction [Etoposide results in increased degradation of PARP1 protein]; BCL2L1 protein results in decreased susceptibility to [Cisplatin co-treated with Etoposide]; Etoposide inhibits the reaction [BAX protein binds to BCL2L1 protein]
Etoposide affects the expression of BCL2L1 protein
BCL2L1 protein results in decreased susceptibility to Etoposide		 CTD PMID:8840993 PMID:10620629 PMID:11468182 PMID:15215046 PMID:15917659 More... NCBI chr20:31,664,452...31,723,963
Ensembl chr20:31,664,452...31,723,989 		JBrowse link
G BCL2L2 BCL2 like 2 decreases response to substance EXP BCL2L2 results in decreased susceptibility to Etoposide CTD PMID:14973057 NCBI chr14:23,306,833...23,311,751
Ensembl chr14:23,298,790...23,311,751 		JBrowse link
G BCL6B BCL6B transcription repressor multiple interactions ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of BCL6B mRNA CTD PMID:29733421 NCBI chr17:7,023,050...7,029,644
Ensembl chr17:7,023,050...7,030,290 		JBrowse link
G BDNF brain derived neurotrophic factor increases expression
multiple interactions		 EXP Etoposide results in increased expression of BDNF mRNA
HIPK2 mutant form inhibits the reaction [Etoposide results in increased expression of BDNF mRNA]		 CTD PMID:20573984 NCBI chr11:27,654,893...27,722,030
Ensembl chr11:27,654,893...27,722,058 		JBrowse link
G BID BH3 interacting domain death agonist multiple interactions
increases expression
increases cleavage		 EXP CASP9 mutant form inhibits the reaction [Etoposide results in increased cleavage of BID protein]; Estradiol inhibits the reaction [Etoposide results in increased expression of BID mRNA] CTD PMID:19426747 PMID:21801448 NCBI chr22:17,734,138...17,774,665
Ensembl chr22:17,734,138...17,774,770 		JBrowse link
G BIK BCL2 interacting killer increases response to substance EXP BIK protein results in increased susceptibility to Etoposide CTD PMID:16007125 NCBI chr22:43,110,750...43,129,712
Ensembl chr22:43,110,750...43,129,712 		JBrowse link
G BIN1 bridging integrator 1 increases response to substance EXP BIN1 protein results in increased susceptibility to Etoposide CTD PMID:21447800 NCBI chr 2:127,048,023...127,107,154
Ensembl chr 2:127,048,027...127,107,288 		JBrowse link
G BIN3 bridging integrator 3 affects response to substance EXP BIN3 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 8:22,620,418...22,669,121
Ensembl chr 8:22,620,418...22,669,148 		JBrowse link
G BIRC2 baculoviral IAP repeat containing 2 affects response to substance
decreases response to substance
increases expression		 EXP BIRC2 protein affects the susceptibility to Etoposide
BIRC2 protein results in decreased susceptibility to Etoposide
Etoposide results in increased expression of BIRC2 mRNA		 CTD PMID:10815900 PMID:14970392 PMID:15050749 PMID:16217747 NCBI chr11:102,347,214...102,378,670
Ensembl chr11:102,347,211...102,378,670 		JBrowse link
G BIRC3 baculoviral IAP repeat containing 3 decreases response to substance
decreases expression
multiple interactions		 EXP BIRC3 protein results in decreased susceptibility to Etoposide
Etoposide results in decreased expression of BIRC3 mRNA
[Etoposide co-treated with KN 62] results in decreased expression of BIRC3 protein		 CTD PMID:14666661 PMID:15050749 PMID:16120219 NCBI chr11:102,317,484...102,339,403
Ensembl chr11:102,317,484...102,339,403 		JBrowse link
G BIRC5 baculoviral IAP repeat containing 5 multiple interactions
decreases response to substance
increases expression		 EXP [FOXO3 protein results in decreased expression of BIRC5 protein] which results in increased susceptibility to Etoposide; BIRC5 protein inhibits the reaction [FOXO3 protein results in increased susceptibility to Etoposide]; BIRC5 protein results in decreased susceptibility to [Cisplatin co-treated with Etoposide]; Estradiol inhibits the reaction [Etoposide results in increased expression of BIRC5 mRNA]
BIRC5 protein results in decreased susceptibility to Etoposide		 CTD PMID:15917659 PMID:16322251 PMID:16364925 PMID:16382892 PMID:19211844 More... NCBI chr17:78,214,253...78,225,635
Ensembl chr17:78,214,186...78,225,636 		JBrowse link
G BIRC7 baculoviral IAP repeat containing 7 decreases response to substance EXP BIRC7 protein results in decreased susceptibility to Etoposide CTD PMID:17437058 NCBI chr20:63,235,905...63,240,495
Ensembl chr20:63,235,883...63,240,495 		JBrowse link
G BLM BLM RecQ like helicase decreases expression EXP Etoposide results in decreased expression of BLM mRNA CTD PMID:24211769 NCBI chr15:90,717,346...90,816,166
Ensembl chr15:90,717,346...90,816,166 		JBrowse link
G BMP6 bone morphogenetic protein 6 multiple interactions EXP Etoposide inhibits the reaction [BMP6 protein results in increased expression of HAMP mRNA] CTD PMID:25633564 NCBI chr 6:7,726,099...7,881,728
Ensembl chr 6:7,726,099...7,881,728 		JBrowse link
G BRCA1 BRCA1 DNA repair associated multiple interactions
increases expression
decreases expression		 EXP BRCA1 protein mutant form inhibits the reaction [Etoposide results in increased expression of CDK2 protein]; BRCA1 protein mutant form inhibits the reaction [Etoposide results in increased expression of RAD52 protein]; BRCA1 protein mutant form inhibits the reaction [Etoposide results in increased expression of RAD54L protein]; BRCA1 protein mutant form inhibits the reaction [Etoposide results in increased expression of XRCC2 protein]; BRCA1 protein mutant form inhibits the reaction [Etoposide results in increased expression of XRCC3 protein]; BRCA1 protein mutant form inhibits the reaction [Etoposide results in increased expression of XRCC4 protein]; pifithrin inhibits the reaction [Etoposide results in increased expression of and affects the localization of BRCA1 protein]
Etoposide results in increased expression of BRCA1 protein
Etoposide results in decreased expression of BRCA1 mRNA		 CTD PMID:15607317 PMID:16417649 PMID:26259609 NCBI chr17:43,044,295...43,170,327
Ensembl chr17:43,044,295...43,170,245 		JBrowse link
G BSCL2 BSCL2 lipid droplet biogenesis associated, seipin increases expression ISO Etoposide results in increased expression of BSCL2 mRNA CTD PMID:22003191 PMID:25270620 NCBI chr11:62,690,262...62,709,537
Ensembl chr11:62,689,289...62,709,845 		JBrowse link
G BTG2 BTG anti-proliferation factor 2 multiple interactions
increases expression		 ISO
EXP		 TRP53 protein affects the reaction [Etoposide results in increased expression of BTG2 mRNA]
TP53 promotes the reaction [Etoposide results in increased expression of BTG2 protein]
Etoposide results in increased expression of BTG2 mRNA; Etoposide results in increased expression of BTG2 protein		 CTD PMID:21382384 PMID:22003191 PMID:24211769 PMID:27358234 NCBI chr 1:203,305,519...203,309,602
Ensembl chr 1:203,305,491...203,309,602 		JBrowse link
G BTG3 BTG anti-proliferation factor 3 decreases expression EXP Etoposide results in decreased expression of BTG3 mRNA CTD PMID:24211769 NCBI chr21:17,593,653...17,612,901
Ensembl chr21:17,593,653...17,612,945 		JBrowse link
G BUB1 BUB1 mitotic checkpoint serine/threonine kinase decreases expression EXP Etoposide results in decreased expression of BUB1 mRNA CTD PMID:16120219 NCBI chr 2:110,637,528...110,678,063
Ensembl chr 2:110,637,528...110,678,063 		JBrowse link
G BUB1B BUB1 mitotic checkpoint serine/threonine kinase B decreases expression EXP Etoposide results in decreased expression of BUB1B mRNA CTD PMID:16120219 NCBI chr15:40,161,069...40,221,123
Ensembl chr15:40,161,023...40,221,123 		JBrowse link
G C1QBP complement C1q binding protein decreases response to substance EXP C1QBP protein results in decreased susceptibility to Etoposide CTD PMID:25354864 NCBI chr17:5,432,777...5,439,155
Ensembl chr17:5,432,777...5,448,830 		JBrowse link
G C4orf19 chromosome 4 open reading frame 19 affects response to substance EXP C4ORF19 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 4:37,453,255...37,593,510
Ensembl chr 4:37,453,925...37,623,495 		JBrowse link
G C5orf22 chromosome 5 open reading frame 22 affects response to substance EXP C5ORF22 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 5:31,532,301...31,555,053
Ensembl chr 5:31,532,287...31,555,053 		JBrowse link
G CAB39 calcium binding protein 39 decreases expression EXP Etoposide results in decreased expression of CAB39 mRNA CTD PMID:17374387 NCBI chr 2:230,712,842...230,821,075
Ensembl chr 2:230,712,842...230,821,075 		JBrowse link
G CADPS2 calcium dependent secretion activator 2 affects response to substance EXP CADPS2 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 7:122,318,411...122,886,460
Ensembl chr 7:122,318,411...122,886,759 		JBrowse link
G CALCA calcitonin related polypeptide alpha multiple interactions
decreases response to substance		 EXP 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [CALCA protein results in decreased susceptibility to Etoposide] CTD PMID:16222118 NCBI chr11:14,966,668...14,972,351
Ensembl chr11:14,966,622...14,972,354 		JBrowse link
G CALM1 calmodulin 1 increases expression EXP Etoposide results in increased expression of CALM1 mRNA CTD PMID:29397400 NCBI chr14:90,396,502...90,408,268
Ensembl chr14:90,396,502...90,408,268 		JBrowse link
G CARD10 caspase recruitment domain family member 10 multiple interactions
increases expression		 EXP Estradiol inhibits the reaction [Etoposide results in increased expression of CARD10 mRNA] CTD PMID:19426747 NCBI chr22:37,490,362...37,519,415
Ensembl chr22:37,490,362...37,519,542 		JBrowse link
G CASP2 caspase 2 increases expression
increases splicing		 EXP Etoposide results in increased expression of CASP2 mRNA alternative form
Etoposide results in increased splicing of CASP2 mRNA		 CTD PMID:14757846 NCBI chr 7:143,288,351...143,307,696
Ensembl chr 7:143,288,215...143,307,696 		JBrowse link
G CASP3 caspase 3 affects expression
increases cleavage
multiple interactions
increases activity
increases expression		 EXP
ISO		 Etoposide affects the expression of CASP3 protein
Etoposide results in increased cleavage of CASP3 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Etoposide results in increased cleavage of CASP3 protein]; 3',4'-dihydroxyflavone analog inhibits the reaction [Etoposide results in increased cleavage of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of BCL2L1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of BCL2L1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [CASP8 co-treated with TP53] affects the reaction [Etoposide results in increased cleavage of CASP3 protein]; [Etoposide co-treated with Mifepristone] results in increased activity of CASP3 protein; [RASSF1 co-treated with Etoposide] results in increased cleavage of CASP3 protein; [STAT1 protein results in increased activity of CASP3 protein] which results in increased susceptibility to Etoposide; [trigonelline co-treated with Etoposide] results in increased cleavage of CASP3 protein; Acetylcysteine inhibits the reaction [Etoposide results in increased cleavage of CASP3 protein]; Aspirin inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; BCL2 protein inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; BCL2L1 protein inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; benzyloxycarbonyl-leucyl-glutamyl-histidyl-aspartic acid fluoromethyl ketone inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; benzyloxycarbonyl-valyl-alanyl-aspartyl-fluoromethane inhibits the reaction [Etoposide results in increased cleavage of CASP3 protein]; CASP8 mutant form inhibits the reaction [Etoposide results in increased cleavage of CASP3 protein]; CD40LG protein inhibits the reaction [Etoposide promotes the reaction [CASP3 protein results in increased cleavage of PARP1 protein]]; CDKN1A mutant form inhibits the reaction [Aspirin inhibits the reaction [Etoposide results in increased activity of CASP3 protein]]; Dehydroascorbic Acid promotes the reaction [Etoposide results in increased activity of CASP3 protein]; Etoposide promotes the reaction [CASP3 protein results in increased cleavage of PARP1 protein]; Etoposide promotes the reaction [Gold results in increased activity of CASP3 protein]; Etoposide promotes the reaction [Nanotubes, Carbon results in increased activity of CASP3 protein]; Etoposide promotes the reaction [Silver results in increased activity of CASP3 protein]; Etoposide results in increased cleavage of and results in increased activity of CASP3 protein; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Etoposide results in increased cleavage of CASP3 protein]; nimesulide inhibits the reaction [Etoposide results in increased cleavage of CASP3 protein]; Oxygen deficiency inhibits the reaction [Etoposide results in increased expression of CASP3 protein]; palbociclib inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; pifithrin promotes the reaction [Etoposide results in increased activity of CASP3 protein]; pifithrin promotes the reaction [Etoposide results in increased cleavage of CASP3 protein]; Tetrachlorodibenzodioxin inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; TMSB4X protein inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; TP73 mutant form inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; TP73 mutant form inhibits the reaction [Etoposide results in increased cleavage of CASP3 protein]; Wortmannin promotes the reaction [Etoposide results in increased cleavage of and results in increased activity of CASP3 protein]
Etoposide results in increased expression of CASP3 protein; Etoposide results in increased expression of CASP3 protein modified form
[Etoposide results in increased activity of GSK3B protein] which results in increased activity of CASP3 protein; Etoposide results in increased activity of CASP3 protein
2-tert-butylhydroquinone inhibits the reaction [Etoposide results in increased cleavage of and results in increased activity of CASP3 protein]; BCL2 protein affects the reaction [[Etoposide results in increased activity of GSK3B protein] which results in increased activity of CASP3 protein]; Etoposide results in increased cleavage of and results in increased activity of CASP3 protein; HIPK2 gene mutant form promotes the reaction [Etoposide results in increased activity of CASP3 protein]; Metoclopramide inhibits the reaction [Etoposide results in increased activity of CASP3 protein]		 CTD PMID:8840993 PMID:10759716 PMID:12871656 PMID:15215046 PMID:15924153 More... NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062 		JBrowse link
G CASP7 caspase 7 multiple interactions
increases activity		 EXP
ISO		 [STAT1 protein results in increased activity of CASP7 protein] which results in increased susceptibility to Etoposide; benzyloxycarbonyl-leucyl-glutamyl-histidyl-aspartic acid fluoromethyl ketone inhibits the reaction [Etoposide results in increased activity of CASP7 protein]; palbociclib inhibits the reaction [Etoposide results in increased activity of CASP7 protein]; pifithrin promotes the reaction [Etoposide results in increased activity of CASP7 protein]; Tetrachlorodibenzodioxin inhibits the reaction [Etoposide results in increased activity of CASP7 protein]; TP73 mutant form inhibits the reaction [Etoposide results in increased activity of CASP7 protein]
2-tert-butylhydroquinone inhibits the reaction [Etoposide results in increased activity of CASP7 protein]		 CTD PMID:18056177 PMID:18649362 PMID:20299546 PMID:21801448 PMID:22275372 More... NCBI chr10:113,679,194...113,730,909
Ensembl chr10:113,679,162...113,730,907 		JBrowse link
G CASP8 caspase 8 multiple interactions
increases response to substance
increases cleavage
increases activity
decreases response to substance		 EXP 3-(3-chloro-4-hydroxyphenylamino)-4-(4-nitrophenyl)-1H-pyrrole-2,5-dione inhibits the reaction [Etoposide results in increased activity of CASP8 protein]; [CASP8 co-treated with TP53] affects the reaction [Etoposide results in increased cleavage of and results in increased activity of CASP9 protein]; [CASP8 co-treated with TP53] affects the reaction [Etoposide results in increased cleavage of CASP3 protein]; [CASP8 co-treated with TP53] affects the reaction [Etoposide results in increased cleavage of PARP1 protein]; [CASP8 co-treated with TP53] inhibits the reaction [CASP8 protein mutant form results in decreased susceptibility to Etoposide]; acetyl-leucyl-glutamyl-histidyl-aspartal inhibits the reaction [Etoposide results in increased activity of CASP8 protein]; CASP8 mutant form inhibits the reaction [Etoposide results in increased cleavage of CASP3 protein]; CASP8 mutant form inhibits the reaction [Etoposide results in increased cleavage of CASP9 protein]; Etoposide results in increased cleavage of and results in increased activity of CASP8 protein; Etoposide results in increased expression of and results in increased cleavage of CASP8 protein; Lithium inhibits the reaction [Etoposide results in increased activity of CASP8 protein]; nimesulide inhibits the reaction [Etoposide results in increased cleavage of and results in increased activity of CASP8 protein]; TP73 mutant form inhibits the reaction [Etoposide results in increased cleavage of CASP8 protein]
CASP8 protein results in increased susceptibility to Etoposide		 CTD PMID:15475000 PMID:21745461 PMID:21801448 PMID:22010212 NCBI chr 2:201,233,463...201,287,711
Ensembl chr 2:201,233,443...201,361,836 		JBrowse link
G CASP9 caspase 9 multiple interactions
increases cleavage
increases activity
affects expression		 EXP [CASP8 co-treated with TP53] affects the reaction [Etoposide results in increased cleavage of and results in increased activity of CASP9 protein]; [Cisplatin co-treated with Etoposide] results in increased activity of CASP9 protein; CASP8 mutant form inhibits the reaction [Etoposide results in increased cleavage of CASP9 protein]; CASP9 mutant form inhibits the reaction [Etoposide results in increased cleavage of BID protein]; Etoposide results in increased cleavage of and results in increased activity of CASP9 protein; HTATIP2 protein promotes the reaction [Etoposide results in increased activity of CASP9 protein]; MYC protein promotes the reaction [Etoposide results in increased cleavage of CASP9 protein]; Nicotine inhibits the reaction [[Cisplatin co-treated with Etoposide] results in increased activity of CASP9 protein]; nimesulide inhibits the reaction [Etoposide results in increased cleavage of and results in increased activity of CASP9 protein]; TMSB4X protein inhibits the reaction [Etoposide results in increased cleavage of and results in increased activity of CASP9 protein]; Wortmannin promotes the reaction [Etoposide results in increased cleavage of CASP9 protein]
Etoposide affects the expression of CASP9 protein		 CTD PMID:12925536 PMID:15215046 PMID:16364925 PMID:16799960 PMID:17935137 More... NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534 		JBrowse link
G CASQ2 calsequestrin 2 decreases expression EXP Etoposide results in decreased expression of CASQ2 mRNA CTD PMID:29397400 NCBI chr 1:115,700,021...115,768,714
Ensembl chr 1:115,698,038...115,793,195 		JBrowse link
G CAST calpastatin multiple interactions EXP CAST inhibits the reaction [Etoposide results in increased degradation of AR protein] CTD PMID:18726991 NCBI chr 5:95,961,429...96,774,683
Ensembl chr 5:96,525,267...96,779,595
Ensembl chr 5:96,525,267...96,779,595 		JBrowse link
G CAT catalase increases response to substance
increases activity
multiple interactions		 EXP
ISO		 CAT results in increased susceptibility to Etoposide
Etoposide results in increased activity of CAT protein
EPO protein inhibits the reaction [Etoposide results in increased activity of CAT protein]		 CTD PMID:21689642 PMID:25451571 PMID:29069929 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060 		JBrowse link
G CCDC51 coiled-coil domain containing 51 decreases expression EXP Etoposide results in decreased expression of CCDC51 mRNA CTD PMID:24211769 NCBI chr 3:48,432,173...48,446,652
Ensembl chr 3:48,432,164...48,440,456 		JBrowse link
G CCDC6 coiled-coil domain containing 6 increases response to substance
decreases response to substance		 EXP CCDC6 results in increased susceptibility to Etoposide
CCDC6 results in decreased susceptibility to Etoposide		 CTD PMID:22363533 PMID:22655027 NCBI chr10:59,788,747...59,906,556
Ensembl chr10:59,788,747...59,906,556 		JBrowse link
G CCL3 C-C motif chemokine ligand 3 increases expression EXP Etoposide results in increased expression of CCL3 protein CTD PMID:10540334 NCBI chr17:36,088,256...36,090,143
Ensembl chr17:36,088,256...36,090,169 		JBrowse link
G CCN2 cellular communication network factor 2 increases expression EXP Etoposide results in increased expression of CCN2 mRNA CTD PMID:29397400 NCBI chr 6:131,948,176...131,951,372
Ensembl chr 6:131,948,176...131,951,372 		JBrowse link
G CCNA2 cyclin A2 multiple interactions
decreases expression		 EXP Etoposide affects the expression of and affects the localization of CCNA2 protein
Etoposide results in decreased expression of CCNA2 mRNA; Etoposide results in decreased expression of CCNA2 protein		 CTD PMID:16120219 PMID:17390037 NCBI chr 4:121,816,444...121,823,883
Ensembl chr 4:121,816,444...121,823,883 		JBrowse link
G CCNB1 cyclin B1 decreases expression EXP Etoposide results in decreased expression of CCNB1 mRNA; Etoposide results in decreased expression of CCNB1 protein CTD PMID:16120219 NCBI chr 5:69,167,150...69,178,245
Ensembl chr 5:69,167,135...69,178,245 		JBrowse link
G CCND1 cyclin D1 increases expression EXP Etoposide results in increased expression of CCND1 mRNA CTD PMID:16120219 NCBI chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474 		JBrowse link
G CCNG1 cyclin G1 increases expression ISO Etoposide results in increased expression of CCNG1 mRNA CTD PMID:25270620 NCBI chr 5:163,437,571...163,457,640
Ensembl chr 5:163,437,569...163,446,151 		JBrowse link
G CCNG2 cyclin G2 increases expression EXP Etoposide results in increased expression of CCNG2 mRNA CTD PMID:18754885 NCBI chr 4:77,157,207...77,170,060
Ensembl chr 4:77,157,207...77,433,388 		JBrowse link
G CCS copper chaperone for superoxide dismutase increases expression EXP Etoposide results in increased expression of CCS mRNA CTD PMID:21527772 NCBI chr11:66,593,185...66,606,019
Ensembl chr11:66,593,153...66,606,019 		JBrowse link
G CCT8 chaperonin containing TCP1 subunit 8 multiple interactions ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of CCT8 protein CTD PMID:29733421 NCBI chr21:29,056,326...29,073,648
Ensembl chr21:29,055,805...29,073,797 		JBrowse link
G CD274 CD274 molecule increases expression EXP Etoposide results in increased expression of CD274 protein CTD PMID:17920123 NCBI chr 9:5,450,542...5,470,554
Ensembl chr 9:5,450,503...5,470,566 		JBrowse link
G CD40LG CD40 ligand multiple interactions
decreases response to substance		 EXP CD40LG protein inhibits the reaction [Etoposide promotes the reaction [CASP3 protein results in increased cleavage of PARP1 protein]]
CD40LG protein results in decreased susceptibility to Etoposide		 CTD PMID:16545138 NCBI chr  X:136,648,158...136,660,390
Ensembl chr  X:136,648,158...136,660,390 		JBrowse link
G CD44 CD44 molecule (IN blood group) affects response to substance
multiple interactions		 EXP CD44 protein affects the susceptibility to Etoposide
[[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of BCL2L1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of BCL2L1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in decreased susceptibility to Etoposide; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in decreased susceptibility to Etoposide; Resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in decreased susceptibility to Etoposide]; Resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in decreased susceptibility to Etoposide]		 CTD PMID:15215046 PMID:19047049 NCBI chr11:35,139,171...35,232,402
Ensembl chr11:35,138,882...35,232,402 		JBrowse link
G CD55 CD55 molecule (Cromer blood group) affects response to substance EXP CD55 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 1:207,321,678...207,360,966
Ensembl chr 1:207,321,519...207,386,804 		JBrowse link
G CD59 CD59 molecule (CD59 blood group) multiple interactions EXP [Cisplatin co-treated with Etoposide] results in decreased expression of CD59 protein CTD PMID:21826740 NCBI chr11:33,703,010...33,736,479
Ensembl chr11:33,703,010...33,736,479 		JBrowse link
G CDC25A cell division cycle 25A decreases expression EXP Etoposide results in decreased expression of CDC25A mRNA CTD PMID:24211769 NCBI chr 3:48,157,146...48,188,417
Ensembl chr 3:48,157,146...48,188,417 		JBrowse link
G CDC25C cell division cycle 25C decreases expression EXP Etoposide results in decreased expression of CDC25C mRNA CTD PMID:16120219 NCBI chr 5:138,285,265...138,338,355
Ensembl chr 5:138,285,269...138,338,355 		JBrowse link
G CDC42BPG CDC42 binding protein kinase gamma increases expression ISO Etoposide results in increased expression of CDC42BPG mRNA CTD PMID:25270620 NCBI chr11:64,823,052...64,844,653
Ensembl chr11:64,823,052...64,844,653 		JBrowse link
G CDC45 cell division cycle 45 decreases expression EXP Etoposide results in decreased expression of CDC45 mRNA CTD PMID:16120219 NCBI chr22:19,479,466...19,520,612
Ensembl chr22:19,479,457...19,520,612 		JBrowse link
G CDC6 cell division cycle 6 decreases expression EXP Etoposide results in decreased expression of CDC6 mRNA CTD PMID:16120219 NCBI chr17:40,287,879...40,304,657
Ensembl chr17:40,287,879...40,304,657 		JBrowse link
G CDK2 cyclin dependent kinase 2 multiple interactions
increases expression
affects response to substance		 EXP BRCA1 protein mutant form inhibits the reaction [Etoposide results in increased expression of CDK2 protein]; CDK2 affects the reaction [Etoposide results in increased phosphorylation of TPI1 protein]
CDK2 protein affects the susceptibility to Etoposide		 CTD PMID:16217747 PMID:16417649 PMID:20149834 NCBI chr12:55,966,830...55,972,789
Ensembl chr12:55,966,781...55,972,789 		JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A multiple interactions
increases expression		 EXP
ISO		 [Etoposide results in increased susceptibility to Benzo(a)pyrene] which results in increased expression of CDKN1A protein; [RASSF1 co-treated with Etoposide] results in increased expression of CDKN1A protein; CDKN1A mutant form inhibits the reaction [Aspirin inhibits the reaction [Etoposide results in increased activity of CASP3 protein]]; CDKN1A protein affects the reaction [Etoposide results in decreased expression of UBE2C protein]; entinostat promotes the reaction [Etoposide results in increased expression of CDKN1A protein]; Etoposide promotes the reaction [entinostat results in increased expression of CDKN1A protein]; Etoposide promotes the reaction [trichostatin A results in increased expression of CDKN1A protein]; Etoposide promotes the reaction [UF010 compound results in increased expression of CDKN1A protein]; KEAP1 protein affects the reaction [Etoposide results in increased expression of CDKN1A protein]; Resveratrol inhibits the reaction [Etoposide results in increased expression of CDKN1A mRNA]; TP53 affects the reaction [Etoposide results in increased expression of CDKN1A mRNA]; TP53 promotes the reaction [Etoposide results in increased expression of CDKN1A protein]; TP53 protein promotes the reaction [[Etoposide results in increased susceptibility to Benzo(a)pyrene] which results in increased expression of CDKN1A protein]; TP53 protein promotes the reaction [Etoposide results in increased expression of CDKN1A protein]; trichostatin A promotes the reaction [Etoposide results in increased expression of CDKN1A protein]; UF010 compound promotes the reaction [Etoposide results in increased expression of CDKN1A protein]
Etoposide results in increased expression of CDKN1A mRNA; Etoposide results in increased expression of CDKN1A protein
[CDKN2A gene mutant form results in increased expression of CDKN2A protein alternative form] inhibits the reaction [Etoposide results in increased expression of CDKN1A protein]; TRP53 affects the reaction [Etoposide results in increased expression of CDKN1A mRNA]
cordycepin inhibits the reaction [Etoposide results in increased expression of CDKN1A mRNA]; Etoposide promotes the reaction [Niacin deficiency results in increased expression of CDKN1A protein]; mithramycin A inhibits the reaction [Etoposide results in increased expression of CDKN1A mRNA]; salubrinal inhibits the reaction [Etoposide results in increased expression of CDKN1A mRNA]		 CTD PMID:14601052 PMID:16120219 PMID:16882877 PMID:17516866 PMID:21212465 More... NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,337 		JBrowse link
G CDKN1B cyclin dependent kinase inhibitor 1B increases expression
multiple interactions		 EXP Etoposide results in increased expression of CDKN1B protein
wortmannin promotes the reaction [Etoposide results in increased expression of CDKN1B protein]		 CTD PMID:17935137 NCBI chr12:12,717,368...12,722,369
Ensembl chr12:12,685,498...12,722,369 		JBrowse link
G CDKN2A cyclin dependent kinase inhibitor 2A multiple interactions
increases expression		 ISO [CDKN2A gene mutant form results in increased expression of CDKN2A protein alternative form] inhibits the reaction [Etoposide results in increased expression of CDKN1A protein]; [CDKN2A gene mutant form results in increased expression of CDKN2A protein alternative form] inhibits the reaction [Etoposide results in increased expression of TRP53 protein]
Etoposide results in increased expression of CDKN2A mRNA
cordycepin inhibits the reaction [Etoposide results in increased expression of CDKN2A mRNA]; mithramycin A inhibits the reaction [Etoposide results in increased expression of CDKN2A mRNA]; salubrinal inhibits the reaction [Etoposide results in increased expression of CDKN2A mRNA]		 CTD PMID:21526190 PMID:23690541 NCBI chr 9:21,967,752...21,995,324
Ensembl chr 9:21,967,752...21,995,301 		JBrowse link
G CDKN3 cyclin dependent kinase inhibitor 3 decreases expression EXP Etoposide results in decreased expression of CDKN3 mRNA CTD PMID:16120219 NCBI chr14:54,397,007...54,420,218
Ensembl chr14:54,396,849...54,420,218 		JBrowse link
G CEACAM1 CEA cell adhesion molecule 1 increases expression EXP Etoposide results in increased expression of CEACAM1 mRNA CTD PMID:17374387 NCBI chr19:42,507,306...42,528,481
Ensembl chr19:42,507,304...42,561,234 		JBrowse link
G CEBPA CCAAT enhancer binding protein alpha decreases expression
increases degradation		 EXP Etoposide results in decreased expression of CEBPA mRNA; Etoposide results in decreased expression of CEBPA protein
Etoposide results in increased degradation of CEBPA protein		 CTD PMID:19662097 NCBI chr19:33,299,934...33,302,534
Ensembl chr19:33,299,934...33,302,534 		JBrowse link
G CEBPZ CCAAT enhancer binding protein zeta decreases expression EXP Etoposide results in decreased expression of CEBPZ mRNA CTD PMID:17374387 NCBI chr 2:37,201,612...37,231,596
Ensembl chr 2:37,201,612...37,231,596 		JBrowse link
G CEL carboxyl ester lipase increases expression EXP Etoposide results in increased expression of CEL mRNA CTD PMID:21527772 NCBI chr 9:133,061,981...133,071,861
Ensembl chr 9:133,061,981...133,071,861 		JBrowse link
G CENPF centromere protein F decreases expression EXP Etoposide results in decreased expression of CENPF mRNA CTD PMID:16120219 NCBI chr 1:214,603,195...214,664,571
Ensembl chr 1:214,603,185...214,664,574 		JBrowse link
G CERCAM cerebral endothelial cell adhesion molecule increases expression ISO Etoposide results in increased expression of CERCAM mRNA CTD PMID:25270620 NCBI chr 9:128,419,160...128,437,351
Ensembl chr 9:128,411,751...128,437,351 		JBrowse link
G CES1 carboxylesterase 1 increases expression ISO Etoposide results in increased expression of CES1D mRNA CTD PMID:25270620 NCBI chr16:55,802,851...55,833,096
Ensembl chr16:55,802,851...55,833,337 		JBrowse link
G CETP cholesteryl ester transfer protein multiple interactions
increases expression		 EXP [Tretinoin co-treated with Etoposide] results in increased expression of CETP mRNA; Etoposide promotes the reaction [NR1H2 protein results in increased expression of CETP mRNA]; Etoposide promotes the reaction [NR1H3 protein results in increased expression of CETP mRNA]; Etoposide promotes the reaction [RXRA protein results in increased expression of CETP mRNA]; NR1H2 mutant form inhibits the reaction [Etoposide results in increased expression of CETP mRNA]; NR1H3 mutant form inhibits the reaction [Etoposide results in increased expression of CETP mRNA]; Tretinoin promotes the reaction [Etoposide promotes the reaction [RXRA protein results in increased expression of CETP mRNA]]; Tretinoin promotes the reaction [Etoposide results in increased expression of CETP protein]
Etoposide results in increased expression of CETP mRNA; Etoposide results in increased expression of CETP protein		 CTD PMID:25914138 NCBI chr16:56,961,950...56,983,845
Ensembl chr16:56,961,923...56,983,845 		JBrowse link
G CFLAR CASP8 and FADD like apoptosis regulator increases expression EXP Etoposide results in increased expression of CFLAR protein CTD PMID:14601052 NCBI chr 2:201,116,164...201,176,687
Ensembl chr 2:201,116,154...201,176,687 		JBrowse link
G CGREF1 cell growth regulator with EF-hand domain 1 increases expression ISO Etoposide results in increased expression of CGREF1 mRNA CTD PMID:25270620 NCBI chr 2:27,099,353...27,119,128
Ensembl chr 2:27,098,889...27,119,128 		JBrowse link
G CHAC1 ChaC glutathione specific gamma-glutamylcyclotransferase 1 decreases expression ISO Etoposide results in decreased expression of CHAC1 mRNA CTD PMID:25270620 NCBI chr15:40,953,471...40,956,512
Ensembl chr15:40,952,962...40,956,512 		JBrowse link
G CHAF1A chromatin assembly factor 1 subunit A decreases expression EXP Etoposide results in decreased expression of CHAF1A mRNA CTD PMID:24211769 NCBI chr19:4,402,640...4,450,830
Ensembl chr19:4,402,640...4,445,018 		JBrowse link
G CHEK1 checkpoint kinase 1 affects response to substance
multiple interactions		 EXP CHEK1 protein affects the susceptibility to Etoposide
TP53 protein affects the reaction [CHEK1 protein affects the susceptibility to Etoposide]		 CTD PMID:18698031 NCBI chr11:125,625,136...125,681,124
Ensembl chr11:125,625,163...125,676,255 		JBrowse link
G CHEK2 checkpoint kinase 2 increases phosphorylation
multiple interactions		 ISO
EXP		 Etoposide results in increased phosphorylation of CHEK2 protein
4-fluoro-2-(4-(4-(2-hydroxypropan-2-yl)pyrrolidin-3-ylamino)-6,7-dimethoxyquinazolin-2-yl)phenol inhibits the reaction [Etoposide results in increased phosphorylation of CHEK2 protein]; pifithrin inhibits the reaction [Etoposide results in increased phosphorylation of CHEK2 protein]		 CTD PMID:21186793 PMID:22242153 PMID:26259609 NCBI chr22:28,687,743...28,741,834
Ensembl chr22:28,687,743...28,742,422 		JBrowse link
G CHI3L1 chitinase 3 like 1 decreases response to substance EXP CHI3L1 results in decreased susceptibility to Etoposide CTD PMID:20506295 NCBI chr 1:203,178,931...203,186,704
Ensembl chr 1:203,178,931...203,186,704 		JBrowse link
G CHUK component of inhibitor of nuclear factor kappa B kinase complex decreases expression EXP Etoposide results in decreased expression of CHUK protein CTD PMID:30177839 NCBI chr10:100,186,319...100,229,596
Ensembl chr10:100,188,300...100,229,596 		JBrowse link
G CIAPIN1 cytokine induced apoptosis inhibitor 1 decreases response to substance EXP CIAPIN1 protein results in decreased susceptibility to Etoposide CTD PMID:18389626 NCBI chr16:57,428,187...57,447,385
Ensembl chr16:57,428,187...57,447,420 		JBrowse link
G CKM creatine kinase, M-type decreases expression EXP Etoposide results in decreased expression of CKM mRNA CTD PMID:29397400 NCBI chr19:45,306,413...45,322,875
Ensembl chr19:45,306,413...45,322,875 		JBrowse link
G CKMT1B creatine kinase, mitochondrial 1B affects response to substance EXP CKMT1B protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr15:43,592,857...43,599,406
Ensembl chr15:43,593,054...43,604,901
Ensembl chr15:43,593,054...43,604,901 		JBrowse link
G COA7 cytochrome c oxidase assembly factor 7 decreases expression EXP Etoposide results in decreased expression of COA7 mRNA CTD PMID:24211769 NCBI chr 1:52,684,449...52,698,347
Ensembl chr 1:52,684,449...52,698,347 		JBrowse link
G COBL cordon-bleu WH2 repeat protein decreases expression ISO Etoposide results in decreased expression of COBL mRNA CTD PMID:25270620 NCBI chr 7:51,016,212...51,316,809
Ensembl chr 7:51,016,212...51,316,818 		JBrowse link
G COL15A1 collagen type XV alpha 1 chain affects response to substance EXP COL15A1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 9:98,943,907...99,070,787
Ensembl chr 9:98,943,179...99,070,787 		JBrowse link
G COL4A1 collagen type IV alpha 1 chain decreases expression ISO Etoposide results in decreased expression of COL4A1 mRNA CTD PMID:25270620 NCBI chr13:110,148,963...110,307,157
Ensembl chr13:110,148,963...110,307,202 		JBrowse link
G COL9A3 collagen type IX alpha 3 chain affects response to substance EXP COL9A3 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr20:62,816,213...62,841,159
Ensembl chr20:62,816,244...62,841,159 		JBrowse link
G COX6A2 cytochrome c oxidase subunit 6A2 decreases expression EXP Etoposide results in decreased expression of COX6A2 mRNA CTD PMID:29397400 NCBI chr16:31,427,731...31,428,360
Ensembl chr16:31,427,731...31,428,360 		JBrowse link
G CPS1 carbamoyl-phosphate synthase 1 affects response to substance EXP CPS1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 2:210,477,685...210,679,107
Ensembl chr 2:210,477,682...210,679,107 		JBrowse link
G CPT2 carnitine palmitoyltransferase 2 decreases expression EXP Etoposide results in decreased expression of CPT2 mRNA CTD PMID:24211769 NCBI chr 1:53,196,824...53,214,197
Ensembl chr 1:53,196,792...53,214,197 		JBrowse link
G CRABP2 cellular retinoic acid binding protein 2 increases expression EXP Etoposide results in increased expression of CRABP2 mRNA CTD PMID:21527772 NCBI chr 1:156,699,606...156,705,784
Ensembl chr 1:156,699,606...156,705,816 		JBrowse link
G CREB1 cAMP responsive element binding protein 1 multiple interactions ISO
EXP		 Etoposide results in increased expression of and results in increased phosphorylation of CREB1 protein; HIPK2 gene mutant form inhibits the reaction [Etoposide results in increased expression of and results in increased phosphorylation of CREB1 protein] CTD PMID:20573984 NCBI chr 2:207,529,962...207,605,988
Ensembl chr 2:207,529,737...207,605,988 		JBrowse link
G CREM cAMP responsive element modulator affects response to substance EXP CREM protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr10:35,126,846...35,212,958
Ensembl chr10:35,126,791...35,212,958 		JBrowse link
G CRIP2 cysteine rich protein 2 increases expression ISO Etoposide results in increased expression of CRIP2 mRNA CTD PMID:25270620 NCBI chr14:105,472,945...105,480,170
Ensembl chr14:105,472,962...105,480,162 		JBrowse link
G CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 affects response to substance EXP CSGALNACT1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 8:19,404,161...19,757,908
Ensembl chr 8:19,404,161...19,758,029 		JBrowse link
G CST1 cystatin SN affects response to substance EXP CST1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr20:23,747,562...23,750,935
Ensembl chr20:23,747,562...23,751,268 		JBrowse link
G CTH cystathionine gamma-lyase affects response to substance EXP CTH protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 1:70,411,268...70,439,851
Ensembl chr 1:70,411,218...70,439,851 		JBrowse link
G CTNNB1 catenin beta 1 multiple interactions EXP [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of BCL2L1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in decreased susceptibility to Etoposide; resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in decreased susceptibility to Etoposide] CTD PMID:19047049 NCBI chr 3:41,199,505...41,240,443
Ensembl chr 3:41,194,741...41,260,096 		JBrowse link
G CXCL12 C-X-C motif chemokine ligand 12 decreases expression EXP Etoposide results in decreased expression of CXCL12 mRNA; Etoposide results in decreased expression of CXCL12 protein CTD PMID:22363485 NCBI chr10:44,370,165...44,385,097
Ensembl chr10:44,370,165...44,386,493 		JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 increases expression
multiple interactions		 EXP Etoposide results in increased expression of CXCL8 mRNA; Etoposide results in increased expression of CXCL8 protein
SB 203580 inhibits the reaction [Etoposide results in increased expression of CXCL8 protein]; Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [Etoposide results in increased expression of CXCL8 protein]		 CTD PMID:10540334 NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716 		JBrowse link
G CYCS cytochrome c, somatic affects localization EXP Etoposide affects the localization of CYCS protein CTD PMID:10759716 NCBI chr 7:25,118,656...25,125,260
Ensembl chr 7:25,118,656...25,125,260 		JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 increases expression
multiple interactions		 EXP Etoposide results in increased expression of CYP1A1 mRNA; Etoposide results in increased expression of CYP1A1 protein
Etoposide promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 protein]; TP53 protein promotes the reaction [Etoposide promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 protein]]; TP53 protein promotes the reaction [Etoposide results in increased expression of CYP1A1 protein]		 CTD PMID:29471073 PMID:31542801 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536 		JBrowse link
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 increases expression EXP Etoposide results in increased expression of CYP1A2 mRNA CTD PMID:31542801 NCBI chr15:74,748,845...74,756,607
Ensembl chr15:74,748,845...74,756,607 		JBrowse link
G CYP26A1 cytochrome P450 family 26 subfamily A member 1 decreases response to substance EXP CYP26A1 protein results in decreased susceptibility to Etoposide CTD PMID:15703382 NCBI chr10:93,073,475...93,077,885
Ensembl chr10:93,073,475...93,077,885 		JBrowse link
G CYP27B1 cytochrome P450 family 27 subfamily B member 1 increases expression EXP Etoposide results in increased expression of CYP27B1 mRNA CTD PMID:17716971 NCBI chr12:57,762,334...57,767,078
Ensembl chr12:57,762,334...57,768,986 		JBrowse link
G CYP2C8 cytochrome P450 family 2 subfamily C member 8 increases expression ISO Etoposide results in increased expression of CYP2C29 mRNA CTD PMID:25270620 NCBI chr10:95,036,772...95,069,497
Ensembl chr10:95,036,772...95,069,497 		JBrowse link
G CYP2S1 cytochrome P450 family 2 subfamily S member 1 decreases expression ISO Etoposide results in decreased expression of CYP2S1 mRNA CTD PMID:25270620 NCBI chr19:41,193,219...41,207,539
Ensembl chr19:41,193,210...41,207,539 		JBrowse link
G CYP3A4 cytochrome P450 family 3 subfamily A member 4 multiple interactions
increases expression
decreases methylation
affects response to substance		 EXP [Etoposide results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA; Cyclosporine inhibits the reaction [CYP3A4 protein results in decreased methylation of Etoposide]; Dexamethasone inhibits the reaction [CYP3A4 protein results in decreased methylation of Etoposide]; Erythromycin inhibits the reaction [CYP3A4 protein results in decreased methylation of Etoposide]; Midazolam inhibits the reaction [CYP3A4 protein results in decreased methylation of Etoposide]
Etoposide results in increased expression of CYP3A4 mRNA
CYP3A4 gene polymorphism affects the susceptibility to Etoposide; CYP3A4 protein affects the susceptibility to Etoposide		 CTD PMID:8114683 PMID:12969965 PMID:17279585 PMID:25455453 PMID:31542801 NCBI chr 7:99,756,967...99,784,184
Ensembl chr 7:99,756,960...99,784,248 		JBrowse link
G CYP3A5 cytochrome P450 family 3 subfamily A member 5 affects response to substance
decreases methylation		 EXP CYP3A5 gene polymorphism affects the susceptibility to Etoposide
CYP3A5 protein results in decreased methylation of Etoposide		 CTD PMID:8114683 PMID:12969965 NCBI chr 7:99,648,194...99,679,996
Ensembl chr 7:99,648,194...99,679,996 		JBrowse link
G CYREN cell cycle regulator of NHEJ affects localization EXP Etoposide affects the localization of CYREN protein alternative form CTD PMID:24610814 NCBI chr 7:135,092,303...135,172,469
Ensembl chr 7:135,092,363...135,170,795 		JBrowse link
G DAB2 DAB adaptor protein 2 affects response to substance EXP DAB2 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 5:39,371,677...39,424,980
Ensembl chr 5:39,371,675...39,462,300 		JBrowse link
G DAPK1 death associated protein kinase 1 increases expression
multiple interactions		 EXP Etoposide results in increased expression of DAPK1 protein; Etoposide results in increased expression of DAPK1 protein modified form
DAPK1 protein promotes the reaction [Etoposide results in decreased expression of IKBKB protein]; DAPK1 protein promotes the reaction [Etoposide results in increased expression of ETS1 protein]; DAPK1 protein promotes the reaction [Etoposide results in increased expression of TP53 protein modified form]; DAPK1 protein promotes the reaction [Etoposide results in increased expression of TP53 protein]		 CTD PMID:30177839 NCBI chr 9:87,497,228...87,708,634
Ensembl chr 9:87,497,228...87,708,634 		JBrowse link
G DBF4 DBF4-CDC7 kinase regulatory subunit decreases expression ISO Etoposide results in decreased expression of DBF4 mRNA CTD PMID:25270620 NCBI chr 7:87,876,493...87,909,553
Ensembl chr 7:87,876,216...87,909,553 		JBrowse link
G DBN1 drebrin 1 affects response to substance EXP DBN1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 5:177,456,610...177,473,634
Ensembl chr 5:177,456,608...177,474,401 		JBrowse link
G DCAF4 DDB1 and CUL4 associated factor 4 increases expression ISO Etoposide results in increased expression of DCAF4 mRNA CTD PMID:25270620 NCBI chr14:72,926,464...72,962,098
Ensembl chr14:72,926,377...72,959,703 		JBrowse link
G DCT dopachrome tautomerase affects response to substance EXP DCT protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr13:94,436,811...94,549,406
Ensembl chr13:94,436,811...94,479,682 		JBrowse link
G DDIT4 DNA damage inducible transcript 4 affects response to substance EXP DDIT4 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr10:72,273,924...72,276,036
Ensembl chr10:72,273,919...72,276,036 		JBrowse link
G DDR1 discoidin domain receptor tyrosine kinase 1 increases expression ISO Etoposide results in increased expression of DDR1 mRNA CTD PMID:25270620 NCBI chr 6:30,880,970...30,900,156
Ensembl chr 6:30,876,421...30,900,156 		JBrowse link
G DES desmin decreases expression EXP Etoposide results in decreased expression of DES mRNA CTD PMID:29397400 NCBI chr 2:219,418,377...219,426,734
Ensembl chr 2:219,418,377...219,426,735 		JBrowse link
G DKK3 dickkopf WNT signaling pathway inhibitor 3 affects response to substance EXP DKK3 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr11:11,963,036...12,009,745
Ensembl chr11:11,956,207...12,009,769 		JBrowse link
G DMD dystrophin affects response to substance
decreases expression		 EXP DMD protein affects the susceptibility to Etoposide
Etoposide results in decreased expression of DMD mRNA		 CTD PMID:16217747 PMID:29397400 NCBI chr  X:31,119,222...33,339,388
Ensembl chr  X:31,097,677...33,339,609 		JBrowse link
G DMRT1 doublesex and mab-3 related transcription factor 1 decreases expression ISO Etoposide results in decreased expression of DMRT1 mRNA CTD PMID:25270620 NCBI chr 9:841,697...969,090
Ensembl chr 9:841,690...969,090 		JBrowse link
G DNMT1 DNA methyltransferase 1 decreases response to substance ISO
EXP		 DNMT1 protein results in decreased susceptibility to Etoposide CTD PMID:18314485 NCBI chr19:10,133,346...10,194,953
Ensembl chr19:10,133,342...10,231,286 		JBrowse link
G DNMT3B DNA methyltransferase 3 beta decreases response to substance EXP DNMT3B protein results in decreased susceptibility to Etoposide CTD PMID:18314485 NCBI chr20:32,762,385...32,809,356
Ensembl chr20:32,762,385...32,809,359 		JBrowse link
G DPP7 dipeptidyl peptidase 7 multiple interactions EXP Etoposide promotes the reaction [[DPP7 protein results in increased cleavage of Dipeptides] which results in increased abundance of 4-nitroaniline] CTD PMID:16725115 NCBI chr 9:137,110,546...137,118,306
Ensembl chr 9:137,110,542...137,118,309 		JBrowse link
G DPYSL2 dihydropyrimidinase like 2 decreases expression ISO Etoposide results in decreased expression of DPYSL2 protein CTD PMID:29733421 NCBI chr 8:26,514,031...26,658,175
Ensembl chr 8:26,514,031...26,658,178 		JBrowse link
G DPYSL4 dihydropyrimidinase like 4 increases expression EXP Etoposide results in increased expression of DPYSL4 mRNA CTD PMID:21527772 NCBI chr10:132,186,948...132,205,759
Ensembl chr10:132,186,948...132,205,759 		JBrowse link
G DUSP2 dual specificity phosphatase 2 affects response to substance EXP DUSP2 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 2:96,143,169...96,145,440
Ensembl chr 2:96,143,169...96,145,440 		JBrowse link
G DUSP4 dual specificity phosphatase 4 affects response to substance
increases expression		 EXP DUSP4 protein affects the susceptibility to Etoposide
Etoposide results in increased expression of DUSP4 mRNA		 CTD PMID:16217747 PMID:29397400 NCBI chr 8:29,333,064...29,350,684
Ensembl chr 8:29,333,064...29,350,684 		JBrowse link
G E2F1 E2F transcription factor 1 multiple interactions EXP E2F1 protein affects the reaction [Etoposide results in increased expression of HIC1 mRNA]; Etoposide promotes the reaction [E2F1 protein binds to HIC1 promoter] CTD PMID:19491197 NCBI chr20:33,675,477...33,686,385
Ensembl chr20:33,675,477...33,686,385 		JBrowse link
G EDN1 endothelin 1 multiple interactions EXP EDN1 mutant form inhibits the reaction [VEGFC protein results in decreased susceptibility to Etoposide] CTD PMID:24184161 NCBI chr 6:12,230,516...12,297,194
Ensembl chr 6:12,290,361...12,297,194 		JBrowse link
G EDNRB endothelin receptor type B decreases expression ISO Etoposide results in decreased expression of EDNRB mRNA CTD PMID:25270620 NCBI chr13:77,895,481...77,975,527
Ensembl chr13:77,895,481...77,975,529 		JBrowse link
G EFS embryonal Fyn-associated substrate increases expression ISO Etoposide results in increased expression of EFS mRNA CTD PMID:25270620 NCBI chr14:23,356,406...23,365,172
Ensembl chr14:23,356,403...23,365,752 		JBrowse link
G EGF epidermal growth factor multiple interactions EXP [EGF protein results in decreased expression of TOP2A protein] which results in decreased susceptibility to Etoposide CTD PMID:16969495 NCBI chr 4:109,912,883...110,013,766
Ensembl chr 4:109,912,883...110,013,766 		JBrowse link
G EGFL8 EGF like domain multiple 8 affects response to substance EXP EGFL8 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 6:32,164,595...32,168,281
Ensembl chr 6:32,164,595...32,168,281 		JBrowse link
G EGFR epidermal growth factor receptor decreases expression EXP Etoposide results in decreased expression of EGFR mRNA; Etoposide results in decreased expression of EGFR protein CTD PMID:15228094 NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628 		JBrowse link
G EI24 EI24 autophagy associated transmembrane protein increases expression EXP Etoposide results in increased expression of EI24 mRNA CTD PMID:17374387 NCBI chr11:125,569,477...125,584,684
Ensembl chr11:125,569,280...125,584,684 		JBrowse link
G EIF2S2 eukaryotic translation initiation factor 2 subunit beta decreases expression ISO Etoposide results in decreased expression of EIF2S2 mRNA CTD PMID:25270620 NCBI chr20:34,088,309...34,112,243
Ensembl chr20:34,088,309...34,112,243 		JBrowse link
G EIF3A eukaryotic translation initiation factor 3 subunit A increases response to substance EXP
ISO		 EIF3A results in increased susceptibility to Etoposide CTD PMID:21610145 NCBI chr10:119,033,670...119,080,817
Ensembl chr10:119,033,670...119,080,817 		JBrowse link
G EMP1 epithelial membrane protein 1 increases expression EXP Etoposide results in increased expression of EMP1 mRNA CTD PMID:21527772 NCBI chr12:13,196,726...13,219,941
Ensembl chr12:13,196,723...13,219,941 		JBrowse link
G EMP2 epithelial membrane protein 2 affects response to substance EXP EMP2 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr16:10,528,422...10,580,598
Ensembl chr16:10,528,422...10,580,632 		JBrowse link
G EMP3 epithelial membrane protein 3 (MAM blood group) increases expression EXP Etoposide results in increased expression of EMP3 mRNA CTD PMID:21527772 NCBI chr19:48,325,552...48,330,553
Ensembl chr19:48,321,509...48,330,553 		JBrowse link
G EN2 engrailed homeobox 2 affects response to substance EXP EN2 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 7:155,458,129...155,464,831
Ensembl chr 7:155,458,129...155,464,831 		JBrowse link
G ENO1 enolase 1 decreases expression ISO Etoposide results in decreased expression of ENO1 protein CTD PMID:29733421 NCBI chr 1:8,861,000...8,878,686
Ensembl chr 1:8,861,000...8,879,190 		JBrowse link
G ENTPD2 ectonucleoside triphosphate diphosphohydrolase 2 decreases expression ISO Etoposide results in decreased expression of ENTPD2 mRNA CTD PMID:25270620 NCBI chr 9:137,048,107...137,054,061
Ensembl chr 9:137,048,107...137,054,061 		JBrowse link
G EP300 E1A binding protein p300 multiple interactions EXP [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of BCL2L1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of BCL2L1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in decreased susceptibility to Etoposide; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in decreased susceptibility to Etoposide; resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in decreased susceptibility to Etoposide]; resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in decreased susceptibility to Etoposide] CTD PMID:19047049 NCBI chr22:41,092,592...41,180,077
Ensembl chr22:41,092,510...41,180,077 		JBrowse link
G EPB41L3 erythrocyte membrane protein band 4.1 like 3 affects response to substance EXP EPB41L3 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr18:5,392,386...5,630,663
Ensembl chr18:5,392,381...5,630,700 		JBrowse link
G EPHX1 epoxide hydrolase 1 increases expression ISO Etoposide results in increased expression of EPHX1 mRNA CTD PMID:21382384 PMID:25270620 NCBI chr 1:225,810,124...225,845,563
Ensembl chr 1:225,810,124...225,845,563 		JBrowse link
G EPM2AIP1 EPM2A interacting protein 1 increases expression EXP Etoposide results in increased expression of EPM2AIP1 mRNA CTD PMID:17374387 NCBI chr 3:36,985,043...36,993,131
Ensembl chr 3:36,985,043...36,993,131 		JBrowse link
G EPO erythropoietin multiple interactions EXP EPO protein inhibits the reaction [Etoposide results in increased activity of CAT protein]; EPO protein results in increased susceptibility to [Organoplatinum Compounds co-treated with Etoposide] CTD PMID:18403296 PMID:29069929 NCBI chr 7:100,720,468...100,723,700
Ensembl chr 7:100,720,468...100,723,700 		JBrowse link
G ERBB2 erb-b2 receptor tyrosine kinase 2 multiple interactions
decreases expression
decreases response to substance
affects response to substance		 EXP 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [ERBB2 results in decreased susceptibility to Etoposide]; 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [ERBB2 results in decreased susceptibility to Etoposide]; [ERBB2 results in increased expression of ABCG2] which results in decreased susceptibility to Etoposide; ABCG2 mutant form inhibits the reaction [ERBB2 results in decreased susceptibility to Etoposide]; Curcumin analog inhibits the reaction [ERBB2 protein results in decreased susceptibility to Etoposide]
Etoposide results in decreased expression of ERBB2 mRNA
ERBB2 protein results in decreased susceptibility to Etoposide; ERBB2 results in decreased susceptibility to Etoposide
ERBB2 protein affects the susceptibility to Etoposide		 CTD PMID:10327070 PMID:15228094 PMID:21712253 PMID:25866362 NCBI chr17:39,688,094...39,728,658
Ensembl chr17:39,687,914...39,730,426 		JBrowse link
G ERBB3 erb-b2 receptor tyrosine kinase 3 affects response to substance
decreases expression		 EXP ERBB3 protein affects the susceptibility to Etoposide
Etoposide results in decreased expression of ERBB3 mRNA		 CTD PMID:15228094 PMID:16217747 PMID:29397400 NCBI chr12:56,080,108...56,103,505
Ensembl chr12:56,076,799...56,103,505 		JBrowse link
G ERBB4 erb-b2 receptor tyrosine kinase 4 decreases expression EXP Etoposide results in decreased expression of ERBB4 mRNA CTD PMID:15228094 NCBI chr 2:211,375,717...212,538,802
Ensembl chr 2:211,375,717...212,538,841 		JBrowse link
G EREG epiregulin increases expression EXP Etoposide results in increased expression of EREG mRNA CTD PMID:15228094 NCBI chr 4:74,365,145...74,388,749
Ensembl chr 4:74,365,145...74,388,749 		JBrowse link
G ERVFRD-1 endogenous retrovirus group FRD member 1, envelope affects response to substance EXP ERVFRD-1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 6:11,102,489...11,111,725
Ensembl chr 6:11,102,324...11,111,845 		JBrowse link
G ESR1 estrogen receptor 1 multiple interactions EXP Etoposide inhibits the reaction [Estradiol results in increased activity of ESR1 protein] CTD PMID:30818834 NCBI chr 6:151,656,672...152,129,619
Ensembl chr 6:151,656,691...152,129,619 		JBrowse link
G ESR2 estrogen receptor 2 increases response to substance
multiple interactions		 EXP ESR2 protein results in increased susceptibility to Etoposide
TP53 protein inhibits the reaction [ESR2 protein results in increased susceptibility to Etoposide]		 CTD PMID:20623183 NCBI chr14:64,226,707...64,338,613
Ensembl chr14:64,084,232...64,338,112 		JBrowse link
G ESRP1 epithelial splicing regulatory protein 1 affects response to substance EXP ESRP1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 8:94,641,174...94,707,466
Ensembl chr 8:94,641,074...94,707,466 		JBrowse link
G ESRRA estrogen related receptor alpha multiple interactions EXP Etoposide inhibits the reaction [XCT790 results in decreased activity of ESRRA protein]; Etoposide promotes the reaction [PPARGC1A protein results in increased activity of ESRRA protein] CTD PMID:30818834 NCBI chr11:64,305,524...64,316,743
Ensembl chr11:64,305,497...64,316,743 		JBrowse link
G ETS1 ETS proto-oncogene 1, transcription factor multiple interactions
increases expression		 EXP DAPK1 protein promotes the reaction [Etoposide results in increased expression of ETS1 protein]; ETS1 protein promotes the reaction [Etoposide results in decreased expression of IKBKB protein]; TP53 protein promotes the reaction [Etoposide results in increased expression of ETS1 protein] CTD PMID:30177839 NCBI chr11:128,458,765...128,587,558
Ensembl chr11:128,458,761...128,587,558 		JBrowse link
G ETV6 ETS variant transcription factor 6 increases response to substance
increases mutagenesis		 EXP ETV6 gene mutant form results in increased susceptibility to Etoposide
Etoposide results in increased mutagenesis of ETV6 gene		 CTD PMID:15217836 PMID:28624474 NCBI chr12:11,649,674...11,895,377
Ensembl chr12:11,649,674...11,895,377 		JBrowse link
G EXOC4 exocyst complex component 4 increases expression ISO Etoposide results in increased expression of EXOC4 mRNA CTD PMID:25270620 NCBI chr 7:133,253,078...134,100,951
Ensembl chr 7:133,253,073...134,066,589 		JBrowse link
G F11R F11 receptor increases expression EXP Etoposide results in increased expression of F11R mRNA CTD PMID:29397400 NCBI chr 1:160,995,211...161,021,152
Ensembl chr 1:160,995,211...161,021,175 		JBrowse link
G F2R coagulation factor II thrombin receptor affects response to substance EXP F2R protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 5:76,716,126...76,735,770
Ensembl chr 5:76,716,126...76,735,770 		JBrowse link
G F3 coagulation factor III, tissue factor increases expression EXP Etoposide results in increased expression of F3 mRNA CTD PMID:12542493 NCBI chr 1:94,529,173...94,541,759
Ensembl chr 1:94,529,173...94,541,759 		JBrowse link
G FADS3 fatty acid desaturase 3 increases expression EXP Etoposide results in increased expression of FADS3 mRNA CTD PMID:21527772 NCBI chr11:61,873,526...61,892,224
Ensembl chr11:61,873,519...61,892,051 		JBrowse link
G FAM171A1 family with sequence similarity 171 member A1 affects response to substance EXP FAM171A1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr10:15,211,643...15,374,554
Ensembl chr10:15,211,643...15,371,289 		JBrowse link
G FAS Fas cell surface death receptor multiple interactions
increases expression		 EXP
ISO		 3-(3-chloro-4-hydroxyphenylamino)-4-(4-nitrophenyl)-1H-pyrrole-2,5-dione inhibits the reaction [Etoposide results in increased expression of and affects the localization of FAS protein]; Etoposide results in increased expression of and affects the localization of FAS protein; Lithium inhibits the reaction [Etoposide results in increased expression of and affects the localization of FAS protein]
Etoposide results in increased expression of FAS mRNA
Etoposide results in increased expression of FAS mRNA; Etoposide results in increased expression of FAS protein		 CTD PMID:12513834 PMID:15475000 PMID:16192531 PMID:29397400 NCBI chr10:88,964,050...89,017,059
Ensembl chr10:88,953,813...89,029,605 		JBrowse link
G FASLG Fas ligand multiple interactions
increases expression
increases activity		 EXP
ISO		 [linsidomine results in increased abundance of Nitric Oxide] inhibits the reaction [Etoposide results in increased activity of FASLG promoter]; [S-Nitroso-N-Acetylpenicillamine results in increased abundance of Nitric Oxide] inhibits the reaction [Etoposide results in increased activity of FASLG promoter]; [S-Nitrosoglutathione results in increased abundance of Nitric Oxide] inhibits the reaction [Etoposide results in increased activity of FASLG promoter]; [spermine nitric oxide complex results in increased abundance of Nitric Oxide] inhibits the reaction [Etoposide results in increased activity of FASLG promoter]; Nitric Oxide inhibits the reaction [Etoposide results in increased activity of FASLG promoter]
Etoposide results in increased expression of FASL mRNA		 CTD PMID:10811113 PMID:12513834 NCBI chr 1:172,659,103...172,666,876
Ensembl chr 1:172,659,103...172,666,876 		JBrowse link
G FASN fatty acid synthase increases expression EXP Etoposide results in increased expression of FASN mRNA CTD PMID:17089011 NCBI chr17:82,078,338...82,098,236
Ensembl chr17:82,078,338...82,098,294 		JBrowse link
G FBL fibrillarin affects localization EXP Etoposide analog affects the localization of FBL protein CTD PMID:10942594 NCBI chr19:39,834,458...39,846,379
Ensembl chr19:39,834,458...39,846,379 		JBrowse link
G FDFT1 farnesyl-diphosphate farnesyltransferase 1 affects response to substance EXP FDFT1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 8:11,795,582...11,839,309
Ensembl chr 8:11,795,573...11,839,395 		JBrowse link
G FDXR ferredoxin reductase increases expression EXP Etoposide results in increased expression of FDXR mRNA CTD PMID:17374387 NCBI chr17:74,862,497...74,872,994
Ensembl chr17:74,862,497...74,873,031 		JBrowse link
G FGF2 fibroblast growth factor 2 affects response to substance EXP FGF2 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 4:122,826,682...122,898,236
Ensembl chr 4:122,826,682...122,898,236 		JBrowse link
G FHL1 four and a half LIM domains 1 affects response to substance EXP FHL1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr  X:136,146,702...136,211,359
Ensembl chr  X:136,146,702...136,211,359 		JBrowse link
G FHL2 four and a half LIM domains 2 decreases expression EXP Etoposide results in decreased expression of FHL2 mRNA CTD PMID:29397400 NCBI chr 2:105,357,712...105,438,529
Ensembl chr 2:105,357,712...105,438,513 		JBrowse link
G FLNC filamin C increases expression EXP Etoposide results in increased expression of FLNC mRNA CTD PMID:21527772 NCBI chr 7:128,830,406...128,859,272
Ensembl chr 7:128,830,406...128,859,274 		JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit decreases response to substance
increases expression
multiple interactions		 ISO
EXP		 FOS protein results in decreased susceptibility to Etoposide
Etoposide results in increased expression of FOS
[Etoposide co-treated with Cyclic AMP] results in increased expression of FOS mRNA; Acetylcysteine inhibits the reaction [Etoposide results in increased expression of FOS]		 CTD PMID:10711420 PMID:18314485 PMID:23824011 NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,282,230 		JBrowse link
G FOSL1 FOS like 1, AP-1 transcription factor subunit increases expression ISO Etoposide results in increased expression of FOSL1 mRNA CTD PMID:25270620 NCBI chr11:65,892,049...65,900,545
Ensembl chr11:65,892,049...65,900,573 		JBrowse link
G FOXF2 forkhead box F2 affects response to substance EXP FOXF2 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 6:1,389,576...1,395,603
Ensembl chr 6:1,389,576...1,395,603 		JBrowse link
G FOXJ2 forkhead box J2 decreases expression EXP Etoposide results in decreased expression of FOXJ2 mRNA CTD PMID:24211769 NCBI chr12:8,032,716...8,055,517
Ensembl chr12:8,032,716...8,055,517 		JBrowse link
G FOXO1 forkhead box O1 increases phosphorylation
multiple interactions		 EXP Etoposide results in increased phosphorylation of FOXO1 protein
wortmannin inhibits the reaction [Etoposide results in increased phosphorylation of FOXO1 protein]		 CTD PMID:17935137 NCBI chr13:40,555,667...40,666,641
Ensembl chr13:40,555,667...40,666,641 		JBrowse link
G FOXO3 forkhead box O3 increases phosphorylation
increases response to substance
multiple interactions		 EXP Etoposide results in increased phosphorylation of FOXO3 protein
FOXO3 protein results in increased susceptibility to Etoposide
[FOXO3 protein results in decreased expression of BIRC5 protein] which results in increased susceptibility to Etoposide; BIRC5 protein inhibits the reaction [FOXO3 protein results in increased susceptibility to Etoposide]; wortmannin inhibits the reaction [Etoposide results in increased phosphorylation of FOXO3 protein]		 CTD PMID:17935137 PMID:19211844 NCBI chr 6:108,559,825...108,684,774
Ensembl chr 6:108,559,835...108,684,774 		JBrowse link
G FTH1 ferritin heavy chain 1 multiple interactions
increases expression		 ISO HIPK2 protein promotes the reaction [Etoposide results in increased expression of FTH1 mRNA] CTD PMID:20980392 NCBI chr11:61,964,285...61,967,634
Ensembl chr11:61,959,718...61,967,634 		JBrowse link
G FTL ferritin light chain increases expression
multiple interactions		 EXP Etoposide results in increased expression of FTL mRNA; Etoposide results in increased expression of FTL protein
1-cyclopropyl-4-(4-((5-methyl-3-(3-(4-(trifluoromethoxy)phenyl)-1,2,4-oxadiazol-5-yl)-1H-pyrazol-1-yl)methyl)pyridin-2-yl)piperazine inhibits the reaction [Etoposide results in increased expression of FTL protein]; ARNT protein affects the reaction [Etoposide results in increased expression of FTL protein]; Etoposide promotes the reaction [HIF1A protein binds to FTL promoter]; FTL protein affects the reaction [Etoposide results in increased expression of ALDH1A1 protein]; FTL protein affects the reaction [Etoposide results in increased expression of KLF4 protein]; FTL protein affects the reaction [Etoposide results in increased expression of SOX2 protein]; HIF1A protein affects the reaction [Etoposide results in increased expression of FTL protein]		 CTD PMID:33969609 NCBI chr19:48,965,309...48,966,879
Ensembl chr19:48,965,309...48,966,879 		JBrowse link
G FUT8 fucosyltransferase 8 affects response to substance EXP FUT8 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr14:65,356,842...65,744,121
Ensembl chr14:65,410,592...65,744,121 		JBrowse link
G FYN FYN proto-oncogene, Src family tyrosine kinase affects response to substance
decreases expression		 EXP
ISO		 FYN protein affects the susceptibility to Etoposide
Etoposide results in decreased expression of FYN mRNA		 CTD PMID:16217747 PMID:25270620 NCBI chr 6:111,660,332...111,873,452
Ensembl chr 6:111,660,332...111,873,452 		JBrowse link
G FZD1 frizzled class receptor 1 decreases expression EXP Etoposide results in decreased expression of FZD1 mRNA CTD PMID:24211769 NCBI chr 7:91,264,433...91,271,326
Ensembl chr 7:91,264,433...91,271,326 		JBrowse link
G FZD5 frizzled class receptor 5 decreases expression ISO Etoposide results in decreased expression of FZD5 mRNA CTD PMID:25270620 NCBI chr 2:207,762,598...207,769,906
Ensembl chr 2:207,762,598...207,769,906 		JBrowse link
G GADD45A growth arrest and DNA damage inducible alpha increases response to substance
multiple interactions
increases expression		 EXP GADD45A protein results in increased susceptibility to Etoposide
IKBKB protein inhibits the reaction [Etoposide results in increased expression of GADD45A protein]
Etoposide results in increased expression of GADD45A mRNA; Etoposide results in increased expression of GADD45A protein		 CTD PMID:19003803 PMID:21527772 PMID:29397400 PMID:30177839 PMID:31542801 NCBI chr 1:67,685,201...67,688,334
Ensembl chr 1:67,685,201...67,688,334 		JBrowse link
G GANAB glucosidase II alpha subunit decreases expression
multiple interactions		 ISO Etoposide results in decreased expression of GANAB protein
[Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of GANAB protein		 CTD PMID:29733421 NCBI chr11:62,624,829...62,646,613
Ensembl chr11:62,624,826...62,646,726 		JBrowse link
G GAPDH glyceraldehyde-3-phosphate dehydrogenase increases expression ISO Etoposide results in increased expression of GAPDH protein CTD PMID:29733421 NCBI chr12:6,534,517...6,538,371
Ensembl chr12:6,534,512...6,538,374 		JBrowse link
G GCLC glutamate-cysteine ligase catalytic subunit multiple interactions EXP [GCLC protein co-treated with GCLM protein] promotes the reaction [ABCC1 protein results in decreased susceptibility to Etoposide]; [GCLC protein co-treated with GCLM protein] results in decreased susceptibility to Etoposide CTD PMID:10900222 NCBI chr 6:53,497,341...53,545,101
Ensembl chr 6:53,497,341...53,616,970 		JBrowse link
G GCLM glutamate-cysteine ligase modifier subunit multiple interactions EXP [GCLC protein co-treated with GCLM protein] promotes the reaction [ABCC1 protein results in decreased susceptibility to Etoposide]; [GCLC protein co-treated with GCLM protein] results in decreased susceptibility to Etoposide CTD PMID:10900222 NCBI chr 1:93,885,199...93,909,430
Ensembl chr 1:93,885,199...93,909,456 		JBrowse link
G GDF15 growth differentiation factor 15 multiple interactions
increases expression		 EXP Etoposide promotes the reaction [[TP53 protein binds to GDF15 promoter] which results in increased expression of GDF15 mRNA]
[Etoposide results in increased expression of TP53 protein] which results in increased expression of GDF15 protein; Etoposide results in increased expression of GDF15 mRNA; Etoposide results in increased expression of GDF15 protein		 CTD PMID:11895857 PMID:16120219 PMID:24211769 PMID:29397400 NCBI chr19:18,386,158...18,389,176
Ensembl chr19:18,374,731...18,389,176 		JBrowse link
G GJA1 gap junction protein alpha 1 multiple interactions
increases response to substance		 ISO GJA1 protein affects the reaction [Simvastatin results in increased susceptibility to Etoposide]; Tetradecanoylphorbol Acetate affects the reaction [GJA1 protein results in increased susceptibility to Etoposide] CTD PMID:23978459 NCBI chr 6:121,435,646...121,449,727
Ensembl chr 6:121,435,595...121,449,727 		JBrowse link
G GJA5 gap junction protein alpha 5 decreases expression EXP Etoposide results in decreased expression of GJA5 mRNA CTD PMID:29397400 NCBI chr 1:147,756,199...147,773,351
Ensembl chr 1:147,756,199...147,773,362 		JBrowse link
G GLS2 glutaminase 2 increases expression EXP Etoposide results in increased expression of GLS2 mRNA CTD PMID:21527772 PMID:29397400 NCBI chr12:56,470,952...56,488,161
Ensembl chr12:56,470,944...56,488,414 		JBrowse link
G GPIHBP1 glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1 decreases expression ISO Etoposide results in decreased expression of GPIHBP1 mRNA CTD PMID:25270620 NCBI chr 8:143,213,218...143,217,170
Ensembl chr 8:143,213,218...143,217,170 		JBrowse link
G GPM6B glycoprotein M6B affects response to substance EXP GPM6B protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr  X:13,770,939...13,938,638
Ensembl chr  X:13,770,939...13,938,638 		JBrowse link
G GPNMB glycoprotein nmb increases expression EXP Etoposide results in increased expression of GPNMB mRNA CTD PMID:29397400 NCBI chr 7:23,246,775...23,275,108
Ensembl chr 7:23,235,967...23,275,108 		JBrowse link
G GPR37 G protein-coupled receptor 37 affects response to substance EXP GPR37 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 7:124,743,885...124,765,792
Ensembl chr 7:124,743,885...124,765,792 		JBrowse link
G GPSM2 G protein signaling modulator 2 affects response to substance EXP GPSM2 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 1:108,876,985...108,934,545
Ensembl chr 1:108,875,350...108,934,545 		JBrowse link
G GPX1 glutathione peroxidase 1 increases expression EXP Etoposide results in increased expression of GPX1 mRNA CTD PMID:29397400 NCBI chr 3:49,357,176...49,358,353
Ensembl chr 3:49,357,174...49,358,605 		JBrowse link
G GPX3 glutathione peroxidase 3 increases expression ISO Etoposide results in increased expression of GPX3 mRNA CTD PMID:25270620 NCBI chr 5:151,020,591...151,028,988
Ensembl chr 5:151,020,591...151,028,988 		JBrowse link
G GRIA3 glutamate ionotropic receptor AMPA type subunit 3 increases expression ISO Etoposide results in increased expression of GRIA3 mRNA CTD PMID:25270620 NCBI chr  X:123,184,278...123,490,915
Ensembl chr  X:123,184,153...123,490,915 		JBrowse link
G GRPEL1 GrpE like 1, mitochondrial decreases expression EXP Etoposide results in decreased expression of GRPEL1 mRNA CTD PMID:24211769 NCBI chr 4:7,058,895...7,068,064
Ensembl chr 4:7,058,671...7,068,085 		JBrowse link
G GSK3B glycogen synthase kinase 3 beta multiple interactions
increases activity		 ISO BCL2 protein affects the reaction [[Etoposide results in increased activity of GSK3B protein] which results in increased activity of CASP3 protein]
[Etoposide results in increased activity of GSK3B protein] which results in increased activity of CASP3 protein; Etoposide results in increased activity of GSK3B protein		 CTD PMID:19408126 NCBI chr 3:119,821,321...120,094,447
Ensembl chr 3:119,821,321...120,094,994 		JBrowse link
G GSTM1 glutathione S-transferase mu 1 affects response to substance EXP GSTM1 gene polymorphism affects the susceptibility to Etoposide CTD PMID:15713801 NCBI chr 1:109,687,817...109,693,745
Ensembl chr 1:109,687,814...109,709,039 		JBrowse link
G GSTM4 glutathione S-transferase mu 4 affects response to substance EXP GSTM4 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 1:109,656,099...109,667,727
Ensembl chr 1:109,656,099...109,665,496 		JBrowse link
G GSTP1 glutathione S-transferase pi 1 multiple interactions
decreases response to substance
affects response to substance		 EXP Curcumin inhibits the reaction [GSTP1 protein results in decreased susceptibility to Etoposide]; Ethacrynic Acid inhibits the reaction [GSTP1 protein results in decreased susceptibility to Etoposide]; GSTP1 protein promotes the reaction [ABCC1 protein results in decreased susceptibility to Etoposide]; Sulfinpyrazone inhibits the reaction [GSTP1 protein results in decreased susceptibility to Etoposide]; verlukast inhibits the reaction [GSTP1 protein results in decreased susceptibility to Etoposide]
GSTP1 gene polymorphism affects the susceptibility to Etoposide		 CTD PMID:10900222 PMID:12969965 PMID:15999103 NCBI chr11:67,583,812...67,586,653
Ensembl chr11:67,583,742...67,586,656 		JBrowse link
G GSTT2 glutathione S-transferase theta 2 (gene/pseudogene) affects response to substance EXP GSTT2 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr22:23,980,134...23,983,915
Ensembl chr22:23,980,058...23,983,915 		JBrowse link
G H2AX H2A.X variant histone multiple interactions
decreases response to substance
increases expression
increases phosphorylation		 EXP
ISO		 Celecoxib inhibits the reaction [Etoposide results in increased phosphorylation of H2AX protein]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Etoposide results in increased phosphorylation of H2AX protein]; nimesulide inhibits the reaction [Etoposide results in increased phosphorylation of H2AX protein]; palbociclib inhibits the reaction [Etoposide results in increased expression of H2AX protein]; pifithrin promotes the reaction [Etoposide results in increased expression of H2AX protein]
H2AX protein results in decreased susceptibility to Etoposide
4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Etoposide results in increased expression of H2AX protein]; RAD54B protein affects the reaction [Etoposide results in increased expression of H2AX protein]; TOP2B protein affects the reaction [Etoposide results in increased expression of H2AX protein]
4,4'-(1,2-dimethyl-1,2-ethanediyl)bis-2,6-piperazinedione inhibits the reaction [Etoposide results in increased expression of H2AX protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Etoposide results in increased expression of H2AX protein]; Bortezomib inhibits the reaction [Etoposide results in increased expression of H2AX protein]; Razoxane inhibits the reaction [Etoposide results in increased expression of H2AX protein]
Etoposide results in increased expression of H2AX protein; Etoposide results in increased expression of H2AX protein modified form		 CTD PMID:17875725 PMID:20643100 PMID:20978201 PMID:21555580 PMID:21745461 More... NCBI chr11:119,093,874...119,095,465
Ensembl chr11:119,093,874...119,095,465 		JBrowse link
G HAL histidine ammonia-lyase decreases expression ISO Etoposide results in decreased expression of HAL mRNA CTD PMID:25270620 NCBI chr12:95,972,662...95,996,344
Ensembl chr12:95,972,662...95,996,365 		JBrowse link
G HAMP hepcidin antimicrobial peptide decreases expression
multiple interactions		 ISO
EXP		 Etoposide results in decreased expression of HAMP mRNA
Etoposide inhibits the reaction [BMP6 protein results in increased expression of HAMP mRNA]		 CTD PMID:25270620 PMID:25633564 NCBI chr19:35,282,528...35,285,143
Ensembl chr19:35,280,716...35,285,143 		JBrowse link
G HBEGF heparin binding EGF like growth factor increases expression EXP Etoposide results in increased expression of HBEGF mRNA CTD PMID:15228094 NCBI chr 5:140,332,843...140,346,603
Ensembl chr 5:140,332,843...140,346,603 		JBrowse link
G HBP1 HMG-box transcription factor 1 decreases expression EXP Etoposide results in decreased expression of HBP1 mRNA CTD PMID:24211769 NCBI chr 7:107,169,003...107,202,522
Ensembl chr 7:107,168,961...107,202,522 		JBrowse link
G HDAC4 histone deacetylase 4 affects response to substance EXP HDAC4 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 2:239,048,168...239,401,649
Ensembl chr 2:239,048,168...239,401,654 		JBrowse link
G HEPH hephaestin affects response to substance EXP HEPH protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr  X:66,162,671...66,268,863
Ensembl chr  X:66,162,671...66,268,867 		JBrowse link
G HIC1 HIC ZBTB transcriptional repressor 1 multiple interactions
increases expression		 EXP E2F1 protein affects the reaction [Etoposide results in increased expression of HIC1 mRNA]; Etoposide promotes the reaction [E2F1 protein binds to HIC1 promoter] CTD PMID:19491197 NCBI chr17:2,055,103...2,063,241
Ensembl chr17:2,054,154...2,063,241 		JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha multiple interactions EXP Etoposide promotes the reaction [HIF1A protein binds to FTL promoter]; HIF1A mutant form inhibits the reaction [Oxygen deficiency results in decreased susceptibility to Etoposide]; HIF1A protein affects the reaction [Etoposide results in increased expression of FTL protein] CTD PMID:23144690 PMID:33969609 NCBI chr14:61,695,513...61,748,258
Ensembl chr14:61,695,513...61,748,259 		JBrowse link
G HIPK2 homeodomain interacting protein kinase 2 increases activity
multiple interactions
decreases response to substance		 EXP
ISO		 Etoposide results in increased activity of HIPK2 protein
HIPK2 gene mutant form inhibits the reaction [Etoposide results in increased expression of and results in increased phosphorylation of CREB1 protein]; HIPK2 gene mutant form promotes the reaction [Etoposide results in increased activity of CASP3 protein]; HIPK2 protein promotes the reaction [Etoposide results in increased expression of FTH1 mRNA]; HIPK2 protein promotes the reaction [Etoposide results in increased expression of NQO1 mRNA]
HIPK2 results in decreased susceptibility to Etoposide
HIPK2 mutant form inhibits the reaction [Etoposide results in increased expression of BDNF mRNA]		 CTD PMID:20573984 PMID:20980392 NCBI chr 7:139,561,570...139,777,998
Ensembl chr 7:139,561,570...139,777,998 		JBrowse link
G HLA-A major histocompatibility complex, class I, A affects expression EXP Etoposide affects the expression of HLA-A mRNA CTD PMID:25811541 NCBI chr 6:29,942,532...29,945,870
Ensembl chr 6:29,941,260...29,949,572 		JBrowse link
G HLA-B major histocompatibility complex, class I, B affects expression EXP Etoposide affects the expression of HLA-B mRNA CTD PMID:25811541 NCBI chr 6:31,353,875...31,357,179
Ensembl chr 6:31,353,872...31,367,067 		JBrowse link
G HLA-E major histocompatibility complex, class I, E affects expression EXP Etoposide affects the expression of HLA-E mRNA CTD PMID:25811541 NCBI chr 6:30,489,509...30,494,194
Ensembl chr 6:30,489,509...30,494,194 		JBrowse link
G HMCES 5-hydroxymethylcytosine binding, ES cell specific decreases expression ISO Etoposide results in decreased expression of HMCES mRNA CTD PMID:25270620 NCBI chr 3:129,278,832...129,306,186
Ensembl chr 3:129,278,828...129,306,186 		JBrowse link
G HMG20B high mobility group 20B affects response to substance EXP HMG20B protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr19:3,572,944...3,579,083
Ensembl chr19:3,572,777...3,579,088 		JBrowse link
G HMGA2 high mobility group AT-hook 2 affects response to substance EXP HMGA2 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr12:65,824,460...65,966,291
Ensembl chr12:65,824,460...65,966,291 		JBrowse link
G HMGB1 high mobility group box 1 decreases response to substance
increases secretion		 EXP HMGB1 protein results in decreased susceptibility to Etoposide
Etoposide results in increased secretion of HMGB1 protein		 CTD PMID:27807322 NCBI chr13:30,456,704...30,617,597
Ensembl chr13:30,456,704...30,617,597 		JBrowse link
G HNRNPH2 heterogeneous nuclear ribonucleoprotein H2 decreases expression ISO Etoposide results in decreased expression of HNRNPH2 protein CTD PMID:29733421 NCBI chr  X:101,408,222...101,414,133
Ensembl chr  X:101,408,222...101,414,133 		JBrowse link
G HOXA5 homeobox A5 affects response to substance EXP HOXA5 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 7:27,141,052...27,143,681
Ensembl chr 7:27,141,052...27,143,681 		JBrowse link
G HSP90AA1 heat shock protein 90 alpha family class A member 1 multiple interactions ISO [Bleomycin co-treated with Cisplatin co-treated with Etoposide] results in increased expression of HSP90AA1 protein CTD PMID:24478030 NCBI chr14:102,080,742...102,139,749
Ensembl chr14:102,080,742...102,139,699 		JBrowse link
G HSP90B1 heat shock protein 90 beta family member 1 multiple interactions ISO [Bleomycin co-treated with Cisplatin co-treated with Etoposide] results in increased expression of HSP90B1 protein CTD PMID:24478030 NCBI chr12:103,930,410...103,947,926
Ensembl chr12:103,930,107...103,953,931 		JBrowse link
G HSPA2 heat shock protein family A (Hsp70) member 2 affects response to substance EXP HSPA2 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr14:64,535,905...64,543,237
Ensembl chr14:64,535,905...64,546,173 		JBrowse link
G HSPE1 heat shock protein family E (Hsp10) member 1 increases expression ISO Etoposide results in increased expression of HSPE1 protein CTD PMID:29733421 NCBI chr 2:197,500,379...197,503,449
Ensembl chr 2:197,500,140...197,503,449 		JBrowse link
G HTATIP2 HIV-1 Tat interactive protein 2 affects response to substance
increases response to substance
multiple interactions		 EXP
ISO		 HTATIP2 protein affects the susceptibility to Etoposide
HTATIP2 protein results in increased susceptibility to Etoposide
HTATIP2 protein promotes the reaction [Etoposide results in increased activity of CASP9 protein]; HTATIP2 protein promotes the reaction [Etoposide results in increased activity of PARP1 protein]		 CTD PMID:16217747 PMID:16799960 NCBI chr11:20,363,714...20,383,782
Ensembl chr11:20,363,685...20,383,782 		JBrowse link
G HTR4 5-hydroxytryptamine receptor 4 affects response to substance EXP HTR4 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 5:148,451,032...148,654,527
Ensembl chr 5:148,446,042...148,677,235 		JBrowse link
G IER5 immediate early response 5 increases expression EXP Etoposide results in increased expression of IER5 mRNA CTD PMID:21527772 NCBI chr 1:181,088,700...181,092,900
Ensembl chr 1:181,088,700...181,092,900 		JBrowse link
G IFITM1 interferon induced transmembrane protein 1 affects response to substance EXP IFITM1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr11:314,040...315,272
Ensembl chr11:310,041...315,272 		JBrowse link
G IGDCC4 immunoglobulin superfamily DCC subclass member 4 increases expression ISO Etoposide results in increased expression of IGDCC4 mRNA CTD PMID:25270620 NCBI chr15:65,381,484...65,422,947
Ensembl chr15:65,381,484...65,422,947 		JBrowse link
G IGF1R insulin like growth factor 1 receptor affects response to substance EXP IGF1R protein affects the susceptibility to Etoposide CTD PMID:15499378 NCBI chr15:98,648,539...98,964,530
Ensembl chr15:98,648,539...98,964,530 		JBrowse link
G IGFBP7 insulin like growth factor binding protein 7 affects response to substance EXP IGFBP7 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 4:57,030,773...57,110,385
Ensembl chr 4:57,030,773...57,110,385 		JBrowse link
G IGH immunoglobulin heavy locus increases mutagenesis EXP Etoposide results in increased mutagenesis of IGH gene CTD PMID:28624474 NCBI chr14:105,586,437...106,879,844 JBrowse link
G IGSF11 immunoglobulin superfamily member 11 decreases expression ISO Etoposide results in decreased expression of IGSF11 mRNA CTD PMID:25270620 NCBI chr 3:118,900,557...119,146,020
Ensembl chr 3:118,900,557...119,146,068 		JBrowse link
G IKBKB inhibitor of nuclear factor kappa B kinase subunit beta affects response to substance
multiple interactions
decreases expression		 ISO
EXP		 IKBKB protein affects the susceptibility to Etoposide
DAPK1 protein promotes the reaction [Etoposide results in decreased expression of IKBKB protein]; ETS1 protein promotes the reaction [Etoposide results in decreased expression of IKBKB protein]; IKBKB protein inhibits the reaction [Etoposide results in increased expression of GADD45A protein]; IKBKB protein promotes the reaction [Etoposide results in increased expression of MDM2 protein modified form]; IKBKB protein promotes the reaction [Etoposide results in increased expression of MDM2 protein]; TP53 protein promotes the reaction [Etoposide results in decreased expression of IKBKB protein]		 CTD PMID:20159942 PMID:30177839 NCBI chr 8:42,271,302...42,332,460
Ensembl chr 8:42,271,302...42,332,460 		JBrowse link
G IL1B interleukin 1 beta increases expression ISO Etoposide results in increased expression of IL1B mRNA CTD PMID:18523641 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL4 interleukin 4 decreases response to substance
multiple interactions		 EXP IL4 protein results in decreased susceptibility to Etoposide
[IL4 protein co-treated with VCAM1 protein] inhibits the reaction [Etoposide results in decreased folding of BAX protein]; [VCAM1 protein co-treated with IL4 protein] inhibits the reaction [Etoposide inhibits the reaction [BAX protein binds to BCL2L1 protein]]; [VCAM1 protein co-treated with IL4 protein] results in decreased susceptibility to Etoposide		 CTD PMID:10620629 NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678 		JBrowse link
G IL6 interleukin 6 multiple interactions
increases expression
increases secretion		 ISO (4-(5-(4-fluorophenyl)-2-methylsulfanyl-3H-imidazol-4-yl)pyridin-2-yl)-(1-phenylethyl)amine inhibits the reaction [Etoposide results in increased expression of IL6 mRNA]; (4-(5-(4-fluorophenyl)-2-methylsulfanyl-3H-imidazol-4-yl)pyridin-2-yl)-(1-phenylethyl)amine inhibits the reaction [Etoposide results in increased secretion of IL6 protein]
Etoposide results in increased expression of IL6 mRNA; Etoposide results in increased expression of IL6 protein		 CTD PMID:15135310 PMID:17003255 PMID:18523641 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G INKA2 inka box actin regulator 2 increases expression ISO Etoposide results in increased expression of INKA2 mRNA CTD PMID:25270620 NCBI chr 1:111,722,064...111,755,797
Ensembl chr 1:111,680,630...111,755,824 		JBrowse link
G INSIG1 insulin induced gene 1 affects response to substance EXP INSIG1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 7:155,297,878...155,310,235
Ensembl chr 7:155,297,776...155,310,235 		JBrowse link
G INTS15 integrator complex subunit 15 decreases expression EXP Etoposide results in decreased expression of INTS15 mRNA CTD PMID:24211769 NCBI chr 7:6,590,021...6,608,726
Ensembl chr 7:6,590,021...6,608,726 		JBrowse link
G IREB2 iron responsive element binding protein 2 multiple interactions
decreases expression		 EXP 1-cyclopropyl-4-(4-((5-methyl-3-(3-(4-(trifluoromethoxy)phenyl)-1,2,4-oxadiazol-5-yl)-1H-pyrazol-1-yl)methyl)pyridin-2-yl)piperazine inhibits the reaction [Etoposide results in decreased expression of IREB2 protein]
Etoposide results in decreased expression of IREB2 mRNA; Etoposide results in decreased expression of IREB2 protein		 CTD PMID:33969609 NCBI chr15:78,437,431...78,501,453
Ensembl chr15:78,437,431...78,501,453 		JBrowse link
G IRS2 insulin receptor substrate 2 affects response to substance EXP IRS2 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr13:109,752,695...109,786,583
Ensembl chr13:109,752,695...109,786,583 		JBrowse link
G IRX4 iroquois homeobox 4 decreases expression EXP Etoposide results in decreased expression of IRX4 mRNA CTD PMID:29397400 NCBI chr 5:1,877,413...1,887,179
Ensembl chr 5:1,877,413...1,887,236 		JBrowse link
G ISG15 ISG15 ubiquitin like modifier increases expression EXP Etoposide results in increased expression of ISG15 mRNA CTD PMID:21527772 NCBI chr 1:1,013,497...1,014,540
Ensembl chr 1:1,001,138...1,014,540 		JBrowse link
G ISG20 interferon stimulated exonuclease gene 20 affects response to substance EXP ISG20 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr15:88,635,632...88,656,483
Ensembl chr15:88,635,670...88,656,483 		JBrowse link
G ISG20L2 interferon stimulated exonuclease gene 20 like 2 decreases expression EXP Etoposide results in decreased expression of ISG20L2 mRNA CTD PMID:24211769 NCBI chr 1:156,721,891...156,728,766
Ensembl chr 1:156,721,891...156,728,766 		JBrowse link
G ITGA2B integrin subunit alpha 2b increases expression EXP Etoposide results in increased expression of ITGA2B mRNA CTD PMID:21527772 NCBI chr17:44,372,181...44,389,649
Ensembl chr17:44,372,180...44,389,649 		JBrowse link
G ITGB3 integrin subunit beta 3 increases response to substance EXP ITGB3 protein results in increased susceptibility to Etoposide CTD PMID:21332719 NCBI chr17:47,253,827...47,313,743
Ensembl chr17:47,253,827...47,313,743 		JBrowse link
G ITPR1 inositol 1,4,5-trisphosphate receptor type 1 affects response to substance EXP ITPR1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 3:4,493,348...4,847,506
Ensembl chr 3:4,493,345...4,847,506 		JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP [Etoposide co-treated with Cyclic AMP] results in increased expression of JUN mRNA CTD PMID:10711420 NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,776,845...58,784,048 		JBrowse link
G KCNAB2 potassium voltage-gated channel subfamily A regulatory beta subunit 2 affects response to substance EXP KCNAB2 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 1:5,992,676...6,101,180
Ensembl chr 1:5,990,927...6,101,193 		JBrowse link
G KCNE3 potassium voltage-gated channel subfamily E regulatory subunit 3 decreases expression ISO Etoposide results in decreased expression of KCNE3 mRNA CTD PMID:25270620 NCBI chr11:74,454,841...74,467,549
Ensembl chr11:74,454,841...74,467,729 		JBrowse link
G KCNN2 potassium calcium-activated channel subfamily N member 2 decreases expression EXP Etoposide results in decreased expression of KCNN2 mRNA CTD PMID:29397400 NCBI chr 5:114,055,978...114,496,496
Ensembl chr 5:114,055,926...114,496,500 		JBrowse link
G KEAP1 kelch like ECH associated protein 1 decreases response to substance
multiple interactions
increases response to substance		 EXP KEAP1 protein results in decreased susceptibility to Etoposide
KEAP1 protein affects the reaction [Etoposide results in increased expression of CDKN1A protein]
KEAP1 mRNA results in increased susceptibility to Etoposide		 CTD PMID:22684020 PMID:26708503 PMID:27982581 NCBI chr19:10,486,125...10,503,356
Ensembl chr19:10,486,125...10,503,558 		JBrowse link
G KIF1A kinesin family member 1A increases expression EXP Etoposide results in increased expression of KIF1A mRNA CTD PMID:21527772 NCBI chr 2:240,713,767...240,821,403
Ensembl chr 2:240,713,761...240,824,293 		JBrowse link
G KIF20A kinesin family member 20A decreases expression EXP Etoposide results in decreased expression of KIF20A mRNA CTD PMID:24211769 NCBI chr 5:138,179,112...138,187,723
Ensembl chr 5:138,178,719...138,187,723 		JBrowse link
G KIF23 kinesin family member 23 decreases expression ISO Etoposide results in decreased expression of KIF23 mRNA CTD PMID:25270620 NCBI chr15:69,414,349...69,448,427
Ensembl chr15:69,414,246...69,448,427 		JBrowse link
G KIT KIT proto-oncogene, receptor tyrosine kinase increases expression
multiple interactions		 ISO Etoposide results in increased expression of KIT protein
[Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in increased expression of KIT protein		 CTD PMID:29733421 NCBI chr 4:54,657,957...54,740,715
Ensembl chr 4:54,657,267...54,740,783 		JBrowse link
G KLF4 KLF transcription factor 4 increases expression
multiple interactions		 EXP Etoposide results in increased expression of KLF4 mRNA; Etoposide results in increased expression of KLF4 protein
FTL protein affects the reaction [Etoposide results in increased expression of KLF4 protein]		 CTD PMID:33969609 NCBI chr 9:107,484,852...107,489,769
Ensembl chr 9:107,484,852...107,490,482 		JBrowse link
G KLF5 KLF transcription factor 5 increases expression EXP Etoposide results in increased expression of KLF5 mRNA CTD PMID:29397400 NCBI chr13:73,054,976...73,077,538
Ensembl chr13:73,054,976...73,077,541 		JBrowse link
G KLF6 KLF transcription factor 6 decreases expression EXP Etoposide results in decreased expression of KLF6 mRNA CTD PMID:24211769 NCBI chr10:3,775,996...3,785,209
Ensembl chr10:3,775,996...3,785,281 		JBrowse link
G KLHL26 kelch like family member 26 increases expression ISO Etoposide results in increased expression of KLHL26 mRNA CTD PMID:25270620 NCBI chr19:18,637,028...18,671,721
Ensembl chr19:18,637,025...18,671,721 		JBrowse link
G KLK2 kallikrein related peptidase 2 multiple interactions EXP Etoposide inhibits the reaction [Dihydrotestosterone results in increased expression of KLK2 mRNA] CTD PMID:20601956 NCBI chr19:50,873,439...50,880,567
Ensembl chr19:50,861,568...50,880,567 		JBrowse link
G KLK3 kallikrein related peptidase 3 multiple interactions EXP Etoposide inhibits the reaction [Dihydrotestosterone results in increased expression of KLK3 mRNA] CTD PMID:20601956 NCBI chr19:50,854,915...50,860,764
Ensembl chr19:50,854,915...50,860,764 		JBrowse link
G KMT2A lysine methyltransferase 2A increases response to substance
increases mutagenesis
increases cleavage		 EXP KMT2A gene mutant form results in increased susceptibility to Etoposide
Etoposide results in increased mutagenesis of KMT2A gene
Etoposide results in increased cleavage of KMT2A gene		 CTD PMID:14712291 PMID:24086652 PMID:28624474 NCBI chr11:118,436,492...118,526,832
Ensembl chr11:118,436,456...118,526,832 		JBrowse link
G KRT19 keratin 19 increases expression EXP Etoposide results in increased expression of KRT19 mRNA CTD PMID:29397400 NCBI chr17:41,523,617...41,528,308
Ensembl chr17:41,523,617...41,528,308 		JBrowse link
G KRT80 keratin 80 increases expression EXP Etoposide results in increased expression of KRT80 mRNA CTD PMID:21527772 NCBI chr12:52,168,996...52,192,014
Ensembl chr12:52,168,996...52,192,014 		JBrowse link
G KYNU kynureninase affects response to substance EXP KYNU protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 2:142,877,664...143,055,833
Ensembl chr 2:142,877,657...143,055,833 		JBrowse link
G LANCL1 LanC like glutathione S-transferase 1 affects response to substance EXP LANCL1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 2:210,431,251...210,477,584
Ensembl chr 2:210,427,131...210,477,652 		JBrowse link
G LAP3 leucine aminopeptidase 3 decreases expression ISO Etoposide results in decreased expression of LAP3 mRNA CTD PMID:25270620 NCBI chr 4:17,577,198...17,607,970
Ensembl chr 4:17,577,198...17,607,972 		JBrowse link
G LCN2 lipocalin 2 increases response to substance ISO LCN2 protein results in increased susceptibility to Etoposide CTD PMID:19860839 NCBI chr 9:128,149,453...128,153,453
Ensembl chr 9:128,149,071...128,153,453 		JBrowse link
G LDB3 LIM domain binding 3 decreases expression EXP Etoposide results in decreased expression of LDB3 mRNA CTD PMID:29397400 NCBI chr10:86,666,788...86,736,072
Ensembl chr10:86,666,785...86,736,072 		JBrowse link
G LGALS3 galectin 3 affects response to substance EXP LGALS3 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr14:55,129,252...55,145,430
Ensembl chr14:55,124,110...55,145,423 		JBrowse link
G LGALS7 galectin 7 increases expression EXP Etoposide results in increased expression of LGALS7 mRNA CTD PMID:21527772 NCBI chr19:38,770,968...38,773,517
Ensembl chr19:38,789,200...38,791,754
Ensembl chr19:38,789,200...38,791,754 		JBrowse link
G LHX1 LIM homeobox 1 multiple interactions
decreases expression		 ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of LHX1 mRNA
Etoposide results in decreased expression of LHX1 mRNA		 CTD PMID:29733421 NCBI chr17:36,936,785...36,944,612
Ensembl chr17:36,936,785...36,944,612 		JBrowse link
G LHX2 LIM homeobox 2 decreases expression EXP Etoposide results in decreased expression of LHX2 mRNA CTD PMID:24211769 NCBI chr 9:124,011,768...124,033,301
Ensembl chr 9:124,001,670...124,033,301 		JBrowse link
G LIF LIF interleukin 6 family cytokine increases expression EXP Etoposide results in increased expression of LIF mRNA CTD PMID:29397400 NCBI chr22:30,240,453...30,246,759
Ensembl chr22:30,240,453...30,246,759 		JBrowse link
G LIMCH1 LIM and calponin homology domains 1 affects response to substance EXP LIMCH1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 4:41,359,607...41,700,044
Ensembl chr 4:41,359,607...41,700,044 		JBrowse link
G LIPA lipase A, lysosomal acid type affects response to substance EXP LIPA protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr10:89,213,572...89,251,775
Ensembl chr10:89,213,569...89,414,557 		JBrowse link
G LRRC47 leucine rich repeat containing 47 decreases expression EXP Etoposide results in decreased expression of LRRC47 mRNA CTD PMID:24211769 NCBI chr 1:3,778,559...3,796,498
Ensembl chr 1:3,778,559...3,796,498 		JBrowse link
G LTBR lymphotoxin beta receptor multiple interactions
increases expression		 EXP Estradiol inhibits the reaction [Etoposide results in increased expression of LTBR mRNA] CTD PMID:19426747 NCBI chr12:6,375,160...6,391,566
Ensembl chr12:6,375,045...6,391,571 		JBrowse link
G LXN latexin increases response to substance ISO LXN protein results in increased susceptibility to Etoposide CTD PMID:25341047 NCBI chr 3:158,666,414...158,672,648
Ensembl chr 3:158,645,822...158,672,648 		JBrowse link
G LY6E lymphocyte antigen 6 family member E affects response to substance EXP LY6E protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 8:143,018,529...143,022,409
Ensembl chr 8:143,017,982...143,023,832 		JBrowse link
G MACF1 microtubule actin crosslinking factor 1 affects response to substance EXP MACF1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 1:39,084,167...39,487,138
Ensembl chr 1:39,081,316...39,487,177 		JBrowse link
G MAGEA12 MAGE family member A12 affects response to substance EXP MAGEA12 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr  X:152,733,757...152,737,669
Ensembl chr  X:152,733,757...152,737,669 		JBrowse link
G MAGEA6 MAGE family member A6 affects response to substance EXP MAGEA6 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr  X:152,766,136...152,769,689
Ensembl chr  X:152,766,136...152,769,716 		JBrowse link
G MAGEC1 MAGE family member C1 affects response to substance EXP MAGEC1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr  X:141,903,894...141,909,374
Ensembl chr  X:141,903,894...141,909,374 		JBrowse link
G MAN2B1 mannosidase alpha class 2B member 1 increases expression ISO Etoposide results in increased expression of MAN2B1 mRNA CTD PMID:25270620 NCBI chr19:12,646,512...12,666,742
Ensembl chr19:12,646,511...12,666,742 		JBrowse link
G MAP2K3 mitogen-activated protein kinase kinase 3 increases expression EXP Etoposide results in increased expression of MAP2K3 mRNA CTD PMID:17374387 NCBI chr17:21,284,711...21,315,240
Ensembl chr17:21,284,672...21,315,232 		JBrowse link
G MAP3K5 mitogen-activated protein kinase kinase kinase 5 decreases expression EXP Etoposide results in decreased expression of MAP3K5 mRNA CTD PMID:17374387 NCBI chr 6:136,557,046...136,793,091
Ensembl chr 6:136,557,046...136,793,097 		JBrowse link
G MAP7 microtubule associated protein 7 affects response to substance EXP MAP7 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 6:136,342,734...136,550,422
Ensembl chr 6:136,342,281...136,550,819 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 multiple interactions
increases phosphorylation		 EXP 3',4'-dihydroxyflavone analog inhibits the reaction [Etoposide results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [Etoposide results in increased phosphorylation of MAPK1 protein]; U 0126 inhibits the reaction [Etoposide results in increased phosphorylation of MAPK1 protein] CTD PMID:16014620 PMID:19720055 PMID:26046675 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680 		JBrowse link
G MAPK12 mitogen-activated protein kinase 12 increases activity
affects response to substance
multiple interactions		 EXP Etoposide results in increased activity of MAPK12 protein
MAPK12 protein affects the susceptibility to Etoposide
[MAPK12 protein results in increased phosphorylation of TOP2A protein] which results in increased susceptibility to Etoposide; [MAPK12 protein results in increased stability of TOP2A protein] which results in increased susceptibility to Etoposide		 CTD PMID:21878638 NCBI chr22:50,252,901...50,261,683
Ensembl chr22:50,245,450...50,261,716 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 multiple interactions
increases phosphorylation		 EXP 3',4'-dihydroxyflavone analog inhibits the reaction [Etoposide results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [Etoposide results in increased phosphorylation of MAPK3 protein]; U 0126 inhibits the reaction [Etoposide results in increased phosphorylation of MAPK3 protein] CTD PMID:16014620 PMID:19720055 PMID:26046675 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506 		JBrowse link
G MAPKAPK2 MAPK activated protein kinase 2 multiple interactions
increases phosphorylation		 ISO (4-(5-(4-fluorophenyl)-2-methylsulfanyl-3H-imidazol-4-yl)pyridin-2-yl)-(1-phenylethyl)amine inhibits the reaction [Etoposide results in increased phosphorylation of MAPKAPK2 protein] CTD PMID:17003255 NCBI chr 1:206,684,905...206,734,281
Ensembl chr 1:206,684,905...206,734,281 		JBrowse link
G MATN2 matrilin 2 affects response to substance EXP MATN2 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 8:97,869,064...98,036,724
Ensembl chr 8:97,868,840...98,036,724 		JBrowse link
G MBP myelin basic protein affects response to substance EXP MBP protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr18:76,978,833...77,133,708
Ensembl chr18:76,978,827...77,133,683 		JBrowse link
G MCAM melanoma cell adhesion molecule increases expression ISO Etoposide results in increased expression of MCAM mRNA CTD PMID:25270620 NCBI chr11:119,308,529...119,317,130
Ensembl chr11:119,308,529...119,321,521 		JBrowse link
G MCL1 MCL1 apoptosis regulator, BCL2 family member multiple interactions
decreases expression		 EXP wortmannin promotes the reaction [Etoposide results in decreased expression of MCL1 protein] CTD PMID:17935137 NCBI chr 1:150,574,558...150,579,610
Ensembl chr 1:150,560,895...150,579,738 		JBrowse link
G MCM10 minichromosome maintenance 10 replication initiation factor decreases expression EXP Etoposide results in decreased expression of MCM10 mRNA CTD PMID:24211769 NCBI chr10:13,161,558...13,211,110
Ensembl chr10:13,161,558...13,211,110 		JBrowse link
G MCM2 minichromosome maintenance complex component 2 decreases expression EXP Etoposide results in decreased expression of MCM2 mRNA CTD PMID:16120219 NCBI chr 3:127,598,411...127,622,436
Ensembl chr 3:127,598,223...127,622,436 		JBrowse link
G MCM6 minichromosome maintenance complex component 6 decreases expression EXP Etoposide results in decreased expression of MCM6 mRNA CTD PMID:16120219 NCBI chr 2:135,839,626...135,876,443
Ensembl chr 2:135,839,626...135,876,443 		JBrowse link
G MCM7 minichromosome maintenance complex component 7 decreases expression EXP Etoposide results in decreased expression of MCM7 mRNA CTD PMID:16120219 NCBI chr 7:100,092,728...100,101,397
Ensembl chr 7:100,092,233...100,101,940 		JBrowse link
G MCM8 minichromosome maintenance 8 homologous recombination repair factor decreases expression EXP Etoposide results in decreased expression of MCM8 mRNA CTD PMID:16120219 NCBI chr20:5,950,652...5,998,977
Ensembl chr20:5,950,652...5,998,977 		JBrowse link
G MDFIC MyoD family inhibitor domain containing affects response to substance EXP MDFIC protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 7:114,922,094...115,019,917
Ensembl chr 7:114,922,094...115,019,917 		JBrowse link
G MDH2 malate dehydrogenase 2 multiple interactions ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of MDH2 protein CTD PMID:29733421 NCBI chr 7:76,048,106...76,067,508
Ensembl chr 7:76,048,051...76,067,508 		JBrowse link
G MDM2 MDM2 proto-oncogene multiple interactions
decreases expression
increases phosphorylation
increases expression
decreases response to substance		 EXP
ISO		 benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Etoposide promotes the reaction [MDM2 protein binds to TOP2A protein]]; Cadmium Chloride affects the reaction [Etoposide results in increased phosphorylation of MDM2 protein]; Etoposide promotes the reaction [MDM2 protein binds to TOP2A protein]; IKBKB protein promotes the reaction [Etoposide results in increased expression of MDM2 protein modified form]; IKBKB protein promotes the reaction [Etoposide results in increased expression of MDM2 protein]; Wortmannin promotes the reaction [Etoposide results in increased phosphorylation of MDM2 protein]
Etoposide results in decreased expression of MDM2 protein
Etoposide results in increased expression of MDM2 mRNA; Etoposide results in increased expression of MDM2 protein; Etoposide results in increased expression of MDM2 protein modified form
Tetrachlorodibenzodioxin inhibits the reaction [Etoposide results in increased expression of MDM2 protein]
MDM2 promoter SNP results in decreased susceptibility to Etoposide		 CTD PMID:15459018 PMID:16120219 PMID:17575151 PMID:17935137 PMID:18096571 More... NCBI chr12:68,808,172...68,850,686
Ensembl chr12:68,808,177...68,845,544 		JBrowse link
G ME2 malic enzyme 2 decreases expression ISO Etoposide results in decreased expression of ME2 protein CTD PMID:29733421 NCBI chr18:50,879,118...50,954,257
Ensembl chr18:50,879,080...50,954,257 		JBrowse link
G MIR135B microRNA 135b increases expression EXP Etoposide results in increased expression of MIR135B mRNA CTD PMID:27570640 NCBI chr 1:205,448,302...205,448,398
Ensembl chr 1:205,448,302...205,448,398 		JBrowse link
G MIR139 microRNA 139 increases expression EXP Etoposide results in increased expression of MIR139 mRNA CTD PMID:29397400 NCBI chr11:72,615,063...72,615,130
Ensembl chr11:72,615,063...72,615,130 		JBrowse link
G MIR182 microRNA 182 increases expression EXP Etoposide results in increased expression of MIR182 mRNA CTD PMID:29397400 NCBI chr 7:129,770,383...129,770,492
Ensembl chr 7:129,770,383...129,770,492 		JBrowse link
G MIR196B microRNA 196b increases expression EXP Etoposide results in increased expression of MIR196B mRNA CTD PMID:27570640 NCBI chr 7:27,169,480...27,169,563
Ensembl chr 7:27,169,480...27,169,563 		JBrowse link
G MIR34C microRNA 34c increases expression EXP Etoposide results in increased expression of MIR34C mRNA CTD PMID:29397400 NCBI chr11:111,513,439...111,513,515
Ensembl chr11:111,513,439...111,513,515 		JBrowse link
G MIR4423 microRNA 4423 increases expression EXP Etoposide results in increased expression of MIR4423 mRNA CTD PMID:29397400 NCBI chr 1:85,133,794...85,133,873
Ensembl chr 1:85,133,794...85,133,873 		JBrowse link
G MIR654 microRNA 654 increases response to substance EXP MIR654 mRNA results in increased susceptibility to Etoposide CTD PMID:20145152 NCBI chr14:101,040,219...101,040,299
Ensembl chr14:101,040,219...101,040,299 		JBrowse link
G MIR765 microRNA 765 increases response to substance EXP MIR765 mRNA results in increased susceptibility to Etoposide CTD PMID:20145152 NCBI chr 1:156,936,131...156,936,244
Ensembl chr 1:156,936,131...156,936,244 		JBrowse link
G MLANA melan-A affects response to substance EXP MLANA protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 9:5,890,889...5,910,606
Ensembl chr 9:5,890,889...5,910,606 		JBrowse link
G MLLT11 MLLT11 transcription factor 7 cofactor affects response to substance EXP MLLT11 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 1:151,060,397...151,069,544
Ensembl chr 1:151,060,397...151,069,544 		JBrowse link
G MMP1 matrix metallopeptidase 1 decreases expression
multiple interactions		 EXP Etoposide results in decreased expression of MMP1 protein
pifithrin inhibits the reaction [Etoposide results in decreased expression of MMP1 protein]		 CTD PMID:18557930 NCBI chr11:102,789,919...102,798,160
Ensembl chr11:102,789,401...102,798,160 		JBrowse link
G MOCOS molybdenum cofactor sulfurase affects response to substance EXP MOCOS protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr18:36,187,497...36,272,157
Ensembl chr18:36,187,497...36,272,157 		JBrowse link
G MPO myeloperoxidase increases metabolic processing EXP MPO protein results in increased metabolism of Etoposide CTD PMID:16841962 NCBI chr17:58,269,855...58,280,935
Ensembl chr17:58,269,855...58,280,935 		JBrowse link
G MPZL1 myelin protein zero like 1 decreases expression EXP Etoposide results in decreased expression of MPZL1 mRNA CTD PMID:24211769 NCBI chr 1:167,721,982...167,791,919
Ensembl chr 1:167,721,192...167,791,919 		JBrowse link
G MR1 major histocompatibility complex, class I-related increases expression
affects expression		 EXP Etoposide results in increased expression of MR1 mRNA
Etoposide affects the expression of MR1 mRNA		 CTD PMID:21527772 PMID:25811541 NCBI chr 1:181,033,387...181,061,938
Ensembl chr 1:181,033,374...181,061,938 		JBrowse link
G MRAS muscle RAS oncogene homolog decreases expression ISO Etoposide results in decreased expression of MRAS mRNA CTD PMID:25270620 NCBI chr 3:138,347,648...138,405,535
Ensembl chr 3:138,347,648...138,405,534 		JBrowse link
G MRC1 mannose receptor C-type 1 decreases expression ISO Etoposide results in decreased expression of MRC1 mRNA CTD PMID:25270620 NCBI chr10:17,809,348...17,911,164
Ensembl chr10:17,809,348...17,911,164 		JBrowse link
G MRM2 mitochondrial rRNA methyltransferase 2 decreases expression EXP Etoposide results in decreased expression of MRM2 mRNA CTD PMID:24211769 NCBI chr 7:2,234,195...2,242,205
Ensembl chr 7:2,234,195...2,242,205 		JBrowse link
G MSC musculin decreases expression ISO Etoposide results in decreased expression of MSC mRNA CTD PMID:25270620 NCBI chr 8:71,841,560...71,844,412
Ensembl chr 8:71,841,560...71,844,412 		JBrowse link
G MSH6 mutS homolog 6 decreases expression EXP Etoposide results in decreased expression of MSH6 mRNA CTD PMID:24211769 NCBI chr 2:47,783,145...47,810,101
Ensembl chr 2:47,695,530...47,810,063 		JBrowse link
G MT-ND4 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4 increases expression EXP Etoposide results in increased expression of ND4 mRNA CTD PMID:26259609 NCBI chr MT:10,760...12,137
Ensembl chr MT:10,760...12,137 		JBrowse link
G MT2A metallothionein 2A multiple interactions
decreases expression		 EXP XAF1 protein affects the reaction [Etoposide results in decreased expression of MT2A protein] CTD PMID:28507149 NCBI chr16:56,608,584...56,609,497
Ensembl chr16:56,608,584...56,609,497 		JBrowse link
G MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase decreases expression ISO Etoposide results in decreased expression of MTHFD2 mRNA CTD PMID:25270620 NCBI chr 2:74,198,615...74,217,565
Ensembl chr 2:74,186,172...74,217,565 		JBrowse link
G MTOR mechanistic target of rapamycin kinase increases phosphorylation EXP Etoposide results in increased phosphorylation of MTOR protein CTD PMID:27769712 NCBI chr 1:11,106,535...11,262,551
Ensembl chr 1:11,106,535...11,262,556 		JBrowse link
G MTUS1 microtubule associated scaffold protein 1 affects response to substance EXP MTUS1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 8:17,643,802...17,801,521
Ensembl chr 8:17,643,795...17,801,094 		JBrowse link
G MXI1 MAX interactor 1, dimerization protein affects response to substance EXP MXI1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr10:110,207,605...110,287,365
Ensembl chr10:110,207,605...110,287,365 		JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor decreases expression
increases response to substance
multiple interactions		 EXP Etoposide results in decreased expression of MYC; Etoposide results in decreased expression of MYC mRNA
MYC protein results in increased susceptibility to Etoposide
MYC protein promotes the reaction [Etoposide results in increased cleavage of CASP9 protein]		 CTD PMID:9454737 PMID:21324178 PMID:21527772 NCBI chr 8:127,735,434...127,742,951
Ensembl chr 8:127,735,434...127,742,951 		JBrowse link
G MYCN MYCN proto-oncogene, bHLH transcription factor multiple interactions
decreases response to substance		 EXP [MYCN protein affects the expression of ABCC1 mRNA] which affects the susceptibility to Etoposide
MYCN protein results in decreased susceptibility to Etoposide		 CTD PMID:10348353 NCBI chr 2:15,940,550...15,947,004
Ensembl chr 2:15,940,550...15,947,007 		JBrowse link
G MYH7 myosin heavy chain 7 decreases expression EXP Etoposide results in decreased expression of MYH7 mRNA CTD PMID:29397400 NCBI chr14:23,412,740...23,435,660
Ensembl chr14:23,412,740...23,435,660 		JBrowse link
G MYL2 myosin light chain 2 decreases expression EXP Etoposide results in decreased expression of MYL2 mRNA CTD PMID:29397400 NCBI chr12:110,910,845...110,921,449
Ensembl chr12:110,909,996...111,052,434 		JBrowse link
G MYL3 myosin light chain 3 decreases expression EXP Etoposide results in decreased expression of MYL3 mRNA CTD PMID:29397400 NCBI chr 3:46,857,872...46,882,182
Ensembl chr 3:46,835,110...46,882,178 		JBrowse link
G MYOM2 myomesin 2 decreases expression EXP Etoposide results in decreased expression of MYOM2 mRNA CTD PMID:29397400 NCBI chr 8:2,045,046...2,145,456
Ensembl chr 8:2,045,046...2,165,552 		JBrowse link
G MYOT myotilin increases expression EXP Etoposide results in increased expression of MYOT mRNA CTD PMID:29397400 NCBI chr 5:137,867,860...137,887,851
Ensembl chr 5:137,867,858...137,887,851 		JBrowse link
G MYT1 myelin transcription factor 1 decreases expression EXP Etoposide results in decreased expression of MYT1 mRNA CTD PMID:16120219 NCBI chr20:64,164,452...64,242,253
Ensembl chr20:64,102,394...64,242,253 		JBrowse link
G NABP2 nucleic acid binding protein 2 multiple interactions
increases acetylation		 EXP 4-(4-((5-(4,5-dimethyl-2-nitrophenyl)-2-furanyl)methylene)-4,5-dihydro-3-methyl-5-oxo-1H-pyrazol-1-yl)benzoic acid inhibits the reaction [Etoposide results in increased acetylation of NABP2 protein] CTD PMID:26170237 NCBI chr12:56,222,015...56,229,854
Ensembl chr12:56,222,015...56,229,854 		JBrowse link
G NAP1L1 nucleosome assembly protein 1 like 1 affects response to substance EXP NAP1L1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr12:76,036,585...76,084,685
Ensembl chr12:76,036,585...76,084,735 		JBrowse link
G NCK2 NCK adaptor protein 2 decreases expression EXP Etoposide results in decreased expression of NCK2 mRNA CTD PMID:17374387 NCBI chr 2:105,744,453...105,894,272
Ensembl chr 2:105,744,912...105,894,274 		JBrowse link
G NECTIN2 nectin cell adhesion molecule 2 decreases expression ISO Etoposide results in decreased expression of NECTIN2 mRNA CTD PMID:25270620 NCBI chr19:44,846,297...44,889,223
Ensembl chr19:44,846,175...44,889,223 		JBrowse link
G NEDD9 neural precursor cell expressed, developmentally down-regulated 9 affects response to substance EXP NEDD9 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 6:11,183,298...11,382,348
Ensembl chr 6:11,183,298...11,382,348 		JBrowse link
G NEK2 NIMA related kinase 2 decreases expression EXP Etoposide results in decreased expression of NEK2 mRNA CTD PMID:16120219 NCBI chr 1:211,658,256...211,675,621
Ensembl chr 1:211,658,657...211,675,630 		JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 decreases response to substance
multiple interactions		 EXP NFE2L2 mRNA results in decreased susceptibility to Etoposide; NFE2L2 protein results in decreased susceptibility to Etoposide
NFE2L2 protein affects the reaction [Etoposide results in increased expression of SRXN1 protein]; NFE2L2 protein affects the reaction [Etoposide results in increased expression of TP53 protein]; trigonelline inhibits the reaction [NFE2L2 protein results in decreased susceptibility to Etoposide]		 CTD PMID:26708503 PMID:27982581 PMID:33148531 NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756 		JBrowse link
G NFKB1 nuclear factor kappa B subunit 1 multiple interactions EXP NFKB1 protein affects the reaction [Etoposide results in increased expression of TP53 protein]; NFKB1 protein affects the reaction [Etoposide results in increased phosphorylation of AKT1 protein] CTD PMID:23396362 NCBI chr 4:102,501,359...102,617,302
Ensembl chr 4:102,501,330...102,617,302 		JBrowse link
G NFKBIA NFKB inhibitor alpha multiple interactions
increases degradation		 EXP wortmannin inhibits the reaction [Etoposide results in increased degradation of NFKBIA protein] CTD PMID:12637521 PMID:17935137 NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749 		JBrowse link
G NHERF1 NHERF family PDZ scaffold protein 1 increases expression ISO Etoposide results in increased expression of NHERF1 mRNA CTD PMID:25270620 NCBI chr17:74,748,628...74,769,353
Ensembl chr17:74,748,628...74,769,353 		JBrowse link
G NIBAN1 niban apoptosis regulator 1 affects response to substance EXP NIBAN1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 1:184,791,032...184,974,508
Ensembl chr 1:184,790,724...184,974,508 		JBrowse link
G NIT2 nitrilase family member 2 multiple interactions ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of NIT2 protein CTD PMID:29733421 NCBI chr 3:100,334,757...100,361,635
Ensembl chr 3:100,334,739...100,361,635 		JBrowse link
G NMT2 N-myristoyltransferase 2 affects response to substance EXP NMT2 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr10:15,105,700...15,168,693
Ensembl chr10:15,102,584...15,168,693 		JBrowse link
G NOS2 nitric oxide synthase 2 increases expression ISO
EXP		 Etoposide results in increased expression of NOS2 mRNA
Etoposide results in increased expression of NOS2 protein		 CTD PMID:15135310 PMID:26259609 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529 		JBrowse link
G NPAS1 neuronal PAS domain protein 1 increases expression EXP Etoposide results in increased expression of NPAS1 mRNA CTD PMID:21527772 NCBI chr19:47,019,837...47,045,775
Ensembl chr19:47,019,837...47,045,775 		JBrowse link
G NPNT nephronectin increases expression ISO Etoposide results in increased expression of NPNT mRNA CTD PMID:25270620 NCBI chr 4:105,895,471...105,971,671
Ensembl chr 4:105,894,775...106,004,027 		JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 affects response to substance
increases expression
multiple interactions		 EXP
ISO		 NQO1 protein affects the susceptibility to Etoposide
Etoposide results in increased expression of NQO1 mRNA
HIPK2 protein promotes the reaction [Etoposide results in increased expression of NQO1 mRNA]		 CTD PMID:16217747 PMID:20980392 PMID:29397400 NCBI chr16:69,709,401...69,726,560
Ensembl chr16:69,706,996...69,726,668 		JBrowse link
G NR0B1 nuclear receptor subfamily 0 group B member 1 decreases expression ISO Etoposide results in decreased expression of NR0B1 mRNA CTD PMID:25270620 NCBI chr  X:30,304,206...30,309,390
Ensembl chr  X:30,304,206...30,309,390 		JBrowse link
G NR1H2 nuclear receptor subfamily 1 group H member 2 affects localization
affects response to substance
multiple interactions		 EXP Etoposide affects the localization of NR1H2 protein
NR1H2 protein affects the susceptibility to Etoposide
Etoposide promotes the reaction [NR1H2 protein results in increased expression of CETP mRNA]; NR1H2 mutant form inhibits the reaction [Etoposide results in increased expression of CETP mRNA]		 CTD PMID:25914138 NCBI chr19:50,376,457...50,383,388
Ensembl chr19:50,329,653...50,383,388 		JBrowse link
G NR1H3 nuclear receptor subfamily 1 group H member 3 multiple interactions
affects response to substance
increases expression		 EXP Etoposide promotes the reaction [NR1H3 protein results in increased expression of CETP mRNA]; Etoposide results in increased expression of and affects the localization of NR1H3 protein; NR1H3 mutant form inhibits the reaction [Etoposide results in increased expression of CETP mRNA]
NR1H3 protein affects the susceptibility to Etoposide
Etoposide results in increased expression of NR1H3 mRNA		 CTD PMID:25914138 NCBI chr11:47,248,300...47,269,033
Ensembl chr11:47,248,300...47,269,033 		JBrowse link
G NR1I2 nuclear receptor subfamily 1 group I member 2 affects response to substance
multiple interactions
increases activity		 EXP NR1I2 protein affects the susceptibility to Etoposide
[Etoposide results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA		 CTD PMID:17279585 PMID:25455453 NCBI chr 3:119,782,101...119,818,487
Ensembl chr 3:119,780,484...119,818,487 		JBrowse link
G NR1I3 nuclear receptor subfamily 1 group I member 3 multiple interactions EXP Etoposide inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased activity of NR1I3 protein] CTD PMID:30818834 NCBI chr 1:161,229,669...161,238,203
Ensembl chr 1:161,229,666...161,238,244 		JBrowse link
G NRAP nebulin related anchoring protein decreases expression EXP Etoposide results in decreased expression of NRAP mRNA CTD PMID:29397400 NCBI chr10:113,588,714...113,664,041
Ensembl chr10:113,588,714...113,664,070 		JBrowse link
G NRG1 neuregulin 1 increases expression EXP Etoposide results in increased expression of NRG1 mRNA CTD PMID:29397400 NCBI chr 8:31,639,245...32,774,046
Ensembl chr 8:31,639,222...32,855,666 		JBrowse link
G NRIP1 nuclear receptor interacting protein 1 affects response to substance
decreases expression		 EXP NRIP1 protein affects the susceptibility to Etoposide
Etoposide results in decreased expression of NRIP1 mRNA; Etoposide results in decreased expression of NRIP1 protein		 CTD PMID:16217747 PMID:25914138 NCBI chr21:14,961,235...15,065,936
Ensembl chr21:14,961,235...15,065,936 		JBrowse link
G NUPR1 nuclear protein 1, transcriptional regulator affects response to substance
decreases expression		 EXP
ISO		 NUPR1 protein affects the susceptibility to Etoposide
Etoposide results in decreased expression of NUPR1 mRNA		 CTD PMID:16217747 PMID:25270620 NCBI chr16:28,532,708...28,538,974
Ensembl chr16:28,532,708...28,539,008 		JBrowse link
G OAT ornithine aminotransferase multiple interactions ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of OAT protein CTD PMID:29733421 NCBI chr10:124,397,303...124,418,923
Ensembl chr10:124,397,303...124,418,976 		JBrowse link
G OCA2 OCA2 melanosomal transmembrane protein affects response to substance EXP OCA2 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr15:27,719,008...28,099,315
Ensembl chr15:27,754,875...28,099,315 		JBrowse link
G OGG1 8-oxoguanine DNA glycosylase decreases expression
multiple interactions		 ISO Etoposide results in decreased expression of OGG1 mRNA
wogonin inhibits the reaction [Etoposide results in decreased expression of OGG1 mRNA]		 CTD PMID:23872129 NCBI chr 3:9,749,952...9,783,108
Ensembl chr 3:9,749,944...9,788,219 		JBrowse link
G P2RX7 purinergic receptor P2X 7 increases expression ISO Etoposide results in increased expression of P2RX7 mRNA CTD PMID:25270620 NCBI chr12:121,132,876...121,188,032
Ensembl chr12:121,132,819...121,188,032 		JBrowse link
G PABPC1 poly(A) binding protein cytoplasmic 1 decreases expression ISO Etoposide results in decreased expression of PABPC1 protein CTD PMID:29733421 NCBI chr 8:100,702,916...100,722,088
Ensembl chr 8:100,685,816...100,722,809 		JBrowse link
G PALB2 partner and localizer of BRCA2 decreases expression EXP Etoposide results in decreased expression of PALB2 mRNA CTD PMID:24211769 NCBI chr16:23,603,165...23,641,310
Ensembl chr16:23,603,160...23,641,321 		JBrowse link
G PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 increases expression ISO Etoposide results in increased expression of PAPSS2 mRNA CTD PMID:25270620 NCBI chr10:87,659,878...87,747,705
Ensembl chr10:87,659,613...87,747,705 		JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 increases cleavage
multiple interactions
increases degradation		 ISO
EXP		 Etoposide results in increased cleavage of PARP1 protein
3',4'-dihydroxyflavone analog inhibits the reaction [Etoposide results in increased cleavage of PARP1 protein]; [CASP8 co-treated with TP53] affects the reaction [Etoposide results in increased cleavage of PARP1 protein]; [Colforsin co-treated with Theophylline] inhibits the reaction [Etoposide results in increased cleavage of PARP1 protein]; [trigonelline co-treated with Etoposide] results in increased cleavage of PARP1 protein; BCL2 protein inhibits the reaction [Etoposide results in increased degradation of PARP1 protein]; BCL2L1 protein inhibits the reaction [Etoposide results in increased degradation of PARP1 protein]; benzyloxycarbonyl-valyl-alanyl-aspartyl-fluoromethane inhibits the reaction [Etoposide results in increased cleavage of PARP1 protein]; CD40LG protein inhibits the reaction [Etoposide promotes the reaction [CASP3 protein results in increased cleavage of PARP1 protein]]; Etoposide promotes the reaction [CASP3 protein results in increased cleavage of PARP1 protein]; HTATIP2 protein promotes the reaction [Etoposide results in increased activity of PARP1 protein]; Nicotine inhibits the reaction [Etoposide results in increased cleavage of PARP1 protein]; PTEN protein modified form promotes the reaction [Etoposide results in increased cleavage of PARP1 protein]; PTEN protein promotes the reaction [Etoposide results in increased cleavage of PARP1 protein]; Wortmannin promotes the reaction [Etoposide results in increased cleavage of PARP1 protein]; XAF1 protein affects the reaction [Etoposide results in increased cleavage of PARP1 protein]
Niacin deficiency affects the reaction [Etoposide results in increased cleavage of PARP1 protein]		 CTD PMID:8840993 PMID:9454737 PMID:12690110 PMID:16014620 PMID:16545138 More... NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154 		JBrowse link
G PBK PDZ binding kinase affects response to substance EXP PBK protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 8:27,809,624...27,837,817
Ensembl chr 8:27,809,624...27,838,082 		JBrowse link
G PCBP2 poly(rC) binding protein 2 multiple interactions ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of PCBP2 protein CTD PMID:29733421 NCBI chr12:53,452,102...53,481,162
Ensembl chr12:53,452,102...53,481,162 		JBrowse link
G PCBP4 poly(rC) binding protein 4 decreases expression ISO Etoposide results in decreased expression of PCBP4 mRNA CTD PMID:25270620 NCBI chr 3:51,957,454...51,967,466
Ensembl chr 3:51,957,454...51,974,016 		JBrowse link
G PCK2 phosphoenolpyruvate carboxykinase 2, mitochondrial decreases expression ISO Etoposide results in decreased expression of PCK2 mRNA CTD PMID:25270620 NCBI chr14:24,094,171...24,104,125
Ensembl chr14:24,094,053...24,110,598 		JBrowse link
G PDE2A phosphodiesterase 2A decreases expression ISO Etoposide results in decreased expression of PDE2A mRNA CTD PMID:25270620 NCBI chr11:72,576,141...72,674,422
Ensembl chr11:72,576,141...72,674,591 		JBrowse link
G PDE4B phosphodiesterase 4B affects response to substance EXP PDE4B protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 1:65,792,510...66,374,579
Ensembl chr 1:65,792,514...66,374,579 		JBrowse link
G PDGFC platelet derived growth factor C affects response to substance EXP PDGFC protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 4:156,760,454...156,971,799
Ensembl chr 4:156,760,454...156,971,799 		JBrowse link
G PDIA3 protein disulfide isomerase family A member 3 multiple interactions ISO [Bleomycin co-treated with Cisplatin co-treated with Etoposide] results in increased expression of PDIA3 protein CTD PMID:24478030 NCBI chr15:43,746,438...43,773,278
Ensembl chr15:43,746,394...43,773,279 		JBrowse link
G PDK1 pyruvate dehydrogenase kinase 1 decreases expression EXP Etoposide results in decreased expression of PDK1 mRNA CTD PMID:29397400 NCBI chr 2:172,555,373...172,724,312
Ensembl chr 2:172,555,373...172,608,669 		JBrowse link
G PDK4 pyruvate dehydrogenase kinase 4 increases expression EXP Etoposide results in increased expression of PDK4 mRNA CTD PMID:29397400 NCBI chr 7:95,583,499...95,596,516
Ensembl chr 7:95,583,499...95,596,516 		JBrowse link
G PDLIM3 PDZ and LIM domain 3 increases expression EXP Etoposide results in increased expression of PDLIM3 mRNA CTD PMID:29397400 NCBI chr 4:185,500,660...185,535,507
Ensembl chr 4:185,500,660...185,535,507 		JBrowse link
G PELO pelota mRNA surveillance and ribosome rescue factor decreases expression EXP Etoposide results in decreased expression of PELO mRNA CTD PMID:24211769 NCBI chr 5:52,787,916...52,804,044
Ensembl chr 5:52,787,916...52,804,044 		JBrowse link
G PERP p53 apoptosis effector related to PMP22 increases expression ISO Etoposide results in increased expression of PERP mRNA CTD PMID:21382384 PMID:25270620 NCBI chr 6:138,088,505...138,107,419
Ensembl chr 6:138,088,505...138,107,419 		JBrowse link
G PHGDH phosphoglycerate dehydrogenase affects response to substance EXP PHGDH protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 1:119,711,934...119,744,215
Ensembl chr 1:119,648,411...119,744,218 		JBrowse link
G PHLDA3 pleckstrin homology like domain family A member 3 increases expression ISO Etoposide results in increased expression of PHLDA3 mRNA CTD PMID:25270620 NCBI chr 1:201,464,278...201,469,188
Ensembl chr 1:201,464,278...201,469,237 		JBrowse link
G PIGA phosphatidylinositol glycan anchor biosynthesis class A multiple interactions EXP [Cisplatin co-treated with Etoposide] results in increased mutagenesis of PIGA CTD PMID:21826740 NCBI chr  X:15,319,451...15,335,554
Ensembl chr  X:15,319,452...15,335,554 		JBrowse link
G PIP5K1B phosphatidylinositol-4-phosphate 5-kinase type 1 beta affects response to substance EXP PIP5K1B protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 9:68,705,240...69,009,176
Ensembl chr 9:68,705,240...69,009,176 		JBrowse link
G PLAU plasminogen activator, urokinase increases expression EXP Etoposide results in increased expression of PLAU mRNA CTD PMID:21527772 NCBI chr10:73,909,164...73,917,494
Ensembl chr10:73,909,177...73,917,496 		JBrowse link
G PLK1 polo like kinase 1 decreases expression ISO Etoposide results in decreased expression of PLK1 mRNA CTD PMID:25270620 NCBI chr16:23,678,889...23,690,367
Ensembl chr16:23,677,656...23,690,367 		JBrowse link
G PLK2 polo like kinase 2 increases expression EXP Etoposide results in increased expression of PLK2 mRNA CTD PMID:21527772 NCBI chr 5:58,453,982...58,460,086
Ensembl chr 5:58,453,982...58,460,139 		JBrowse link
G PLK3 polo like kinase 3 increases expression EXP Etoposide results in increased expression of PLK3 mRNA CTD PMID:17374387 NCBI chr 1:44,800,377...44,805,990
Ensembl chr 1:44,800,377...44,805,990 		JBrowse link
G PLP1 proteolipid protein 1 affects response to substance EXP PLP1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr  X:103,776,506...103,792,619
Ensembl chr  X:103,773,718...103,792,619 		JBrowse link
G PLPP2 phospholipid phosphatase 2 decreases expression ISO Etoposide results in decreased expression of PLPP2 mRNA CTD PMID:25270620 NCBI chr19:281,043...291,403
Ensembl chr19:281,040...291,403 		JBrowse link
G PM20D1 peptidase M20 domain containing 1 increases expression ISO Etoposide results in increased expression of PM20D1 mRNA CTD PMID:25270620 NCBI chr 1:205,828,025...205,850,132
Ensembl chr 1:205,828,025...205,850,132 		JBrowse link
G PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 increases expression EXP Etoposide results in increased expression of PMAIP1 mRNA CTD PMID:21801448 NCBI chr18:59,899,996...59,904,305
Ensembl chr18:59,899,996...59,904,305 		JBrowse link
G PMEL premelanosome protein affects response to substance EXP PMEL protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr12:55,954,105...55,966,709
Ensembl chr12:55,954,105...55,973,317 		JBrowse link
G PMP2 peripheral myelin protein 2 affects response to substance EXP PMP2 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 8:81,440,326...81,447,439
Ensembl chr 8:81,440,326...81,447,439 		JBrowse link
G PMP22 peripheral myelin protein 22 affects response to substance EXP PMP22 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr17:15,229,779...15,265,326
Ensembl chr17:15,229,773...15,272,292 		JBrowse link
G POLQ DNA polymerase theta decreases response to substance ISO POLQ results in decreased susceptibility to Etoposide CTD PMID:21883722 NCBI chr 3:121,431,431...121,545,988
Ensembl chr 3:121,431,431...121,545,988 		JBrowse link
G POLR1H RNA polymerase I subunit H decreases response to substance
multiple interactions		 EXP POLR1H protein results in decreased susceptibility to Etoposide
Verapamil inhibits the reaction [POLR1H protein results in decreased susceptibility to Etoposide]		 CTD PMID:14726695 NCBI chr 6:30,060,062...30,064,907
Ensembl chr 6:30,058,899...30,064,909 		JBrowse link
G POMZP3 POM121 and ZP3 fusion affects response to substance EXP POMZP3 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 7:76,609,986...76,627,279
Ensembl chr 7:76,609,986...76,627,279 		JBrowse link
G POSTN periostin increases expression EXP Etoposide results in increased expression of POSTN mRNA CTD PMID:29397400 NCBI chr13:37,562,585...37,598,768
Ensembl chr13:37,562,583...37,598,844 		JBrowse link
G POU5F1 POU class 5 homeobox 1 increases expression EXP Etoposide results in increased expression of POU5F1 mRNA; Etoposide results in increased expression of POU5F1 protein CTD PMID:33969609 NCBI chr 6:31,164,337...31,170,682
Ensembl chr 6:31,164,337...31,180,731 		JBrowse link
G PPARGC1A PPARG coactivator 1 alpha increases expression
multiple interactions		 EXP Etoposide results in increased expression of PPARGC1A mRNA
Etoposide promotes the reaction [PPARGC1A protein results in increased activity of ESRRA protein]		 CTD PMID:26259609 PMID:30818834 NCBI chr 4:23,792,021...24,472,905
Ensembl chr 4:23,755,041...23,904,089 		JBrowse link
G PPARGC1B PPARG coactivator 1 beta increases expression EXP Etoposide results in increased expression of PPARGC1B mRNA CTD PMID:26259609 NCBI chr 5:149,730,310...149,857,959
Ensembl chr 5:149,730,298...149,855,022 		JBrowse link
G PPM1D protein phosphatase, Mg2+/Mn2+ dependent 1D increases expression EXP Etoposide results in increased expression of PPM1D protein CTD PMID:25078064 NCBI chr17:60,600,193...60,666,280
Ensembl chr17:60,600,193...60,666,280 		JBrowse link
G PPP1R13L protein phosphatase 1 regulatory subunit 13 like decreases response to substance
multiple interactions
increases expression		 EXP PPP1R13L results in decreased susceptibility to Etoposide
Etoposide results in increased expression of and results in increased localization of PPP1R13L protein
Etoposide results in increased expression of PPP1R13L mRNA		 CTD PMID:17570360 PMID:19299014 NCBI chr19:45,379,638...45,406,361
Ensembl chr19:45,379,638...45,406,349 		JBrowse link
G PRC1 protein regulator of cytokinesis 1 decreases expression EXP Etoposide results in decreased expression of PRC1 mRNA CTD PMID:17374387 NCBI chr15:90,966,040...90,994,535
Ensembl chr15:90,966,040...90,995,629 		JBrowse link
G PRDX1 peroxiredoxin 1 decreases expression ISO Etoposide results in decreased expression of PRDX1 protein CTD PMID:29733421 NCBI chr 1:45,511,051...45,522,890
Ensembl chr 1:45,510,914...45,542,732 		JBrowse link
G PRKAB1 protein kinase AMP-activated non-catalytic subunit beta 1 increases expression EXP Etoposide results in increased expression of PRKAB1 mRNA CTD PMID:24211769 NCBI chr12:119,667,952...119,681,619
Ensembl chr12:119,667,864...119,681,624 		JBrowse link
G PRKCD protein kinase C delta multiple interactions EXP Etoposide results in increased cleavage of and results in increased activity of PRKCD protein CTD PMID:19662097 NCBI chr 3:53,161,209...53,192,717
Ensembl chr 3:53,156,009...53,192,717 		JBrowse link
G PRKCZ protein kinase C zeta increases response to substance EXP PRKCZ protein results in increased susceptibility to Etoposide CTD PMID:21863889 NCBI chr 1:2,048,504...2,185,395
Ensembl chr 1:2,050,411...2,185,395 		JBrowse link
G PRKDC protein kinase, DNA-activated, catalytic subunit increases phosphorylation
multiple interactions		 EXP Etoposide results in increased phosphorylation of PRKDC protein
PRKDC protein promotes the reaction [Etoposide results in increased phosphorylation of SP1 protein]		 CTD PMID:17441964 NCBI chr 8:47,773,111...47,960,136
Ensembl chr 8:47,773,111...47,960,178 		JBrowse link
G PRKX protein kinase cAMP-dependent X-linked catalytic subunit increases expression EXP Etoposide results in increased expression of PRKX mRNA CTD PMID:29397400 NCBI chr  X:3,604,340...3,713,649
Ensembl chr  X:3,604,340...3,713,649 		JBrowse link
G PRNP prion protein (Kanno blood group) decreases response to substance EXP PRNP protein results in decreased susceptibility to Etoposide CTD PMID:15386405 NCBI chr20:4,686,456...4,701,588
Ensembl chr20:4,686,350...4,701,590 		JBrowse link
G PROCR protein C receptor increases expression EXP Etoposide results in increased expression of PROCR mRNA CTD PMID:21527772 NCBI chr20:35,171,096...35,216,259
Ensembl chr20:35,172,072...35,216,240 		JBrowse link
G PSMD13 proteasome 26S subunit, non-ATPase 13 multiple interactions ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of PSMD13 protein CTD PMID:29733421 NCBI chr11:236,976...252,984
Ensembl chr11:236,966...252,984 		JBrowse link
G PTEN phosphatase and tensin homolog multiple interactions
increases response to substance		 EXP PTEN protein inhibits the reaction [Etoposide results in increased phosphorylation of and results in increased activity of AKT1 protein]; PTEN protein modified form promotes the reaction [Etoposide results in increased cleavage of PARP1 protein]; PTEN protein promotes the reaction [Etoposide results in increased cleavage of PARP1 protein]; wortmannin inhibits the reaction [PTEN protein results in increased susceptibility to Etoposide] CTD PMID:16807353 PMID:17935137 NCBI chr10:87,863,625...87,971,930
Ensembl chr10:87,862,638...87,971,930 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 increases expression
multiple interactions		 EXP Etoposide results in increased expression of PTGS2 protein
PTGS2 mutant form inhibits the reaction [VEGFC protein results in decreased susceptibility to Etoposide]		 CTD PMID:24184161 PMID:26259609 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922 		JBrowse link
G PUS3 pseudouridine synthase 3 decreases expression EXP Etoposide results in decreased expression of PUS3 mRNA CTD PMID:24211769 NCBI chr11:125,893,485...125,903,206
Ensembl chr11:125,893,485...125,903,221 		JBrowse link
G PYGM glycogen phosphorylase, muscle associated decreases expression EXP Etoposide results in decreased expression of PYGM mRNA CTD PMID:29397400 NCBI chr11:64,746,389...64,760,715
Ensembl chr11:64,746,389...64,759,974 		JBrowse link
G RAB17 RAB17, member RAS oncogene family affects response to substance EXP RAB17 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 2:237,574,326...237,590,734
Ensembl chr 2:237,574,322...237,601,614 		JBrowse link
G RAB20 RAB20, member RAS oncogene family affects response to substance EXP RAB20 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr13:110,523,066...110,561,722
Ensembl chr13:110,523,066...110,561,722 		JBrowse link
G RAD51 RAD51 recombinase affects localization ISO Etoposide affects the localization of RAD51 protein CTD PMID:9885240 NCBI chr15:40,694,733...40,732,340
Ensembl chr15:40,694,774...40,732,340 		JBrowse link
G RAD52 RAD52 homolog, DNA repair protein multiple interactions
increases expression		 EXP BRCA1 protein mutant form inhibits the reaction [Etoposide results in increased expression of RAD52 protein]
Etoposide results in increased expression of RAD52 mRNA; Etoposide results in increased expression of RAD52 protein		 CTD PMID:16417649 PMID:19799994 NCBI chr12:911,736...991,122
Ensembl chr12:911,736...990,053 		JBrowse link
G RAD54B RAD54 homolog B multiple interactions ISO RAD54B protein affects the reaction [Etoposide results in increased expression of H2AX protein] CTD PMID:33823233 NCBI chr 8:94,371,960...94,475,115
Ensembl chr 8:94,371,960...94,475,115 		JBrowse link
G RAD54L RAD54 like increases expression
multiple interactions		 EXP Etoposide results in increased expression of RAD54L protein
BRCA1 protein mutant form inhibits the reaction [Etoposide results in increased expression of RAD54L protein]		 CTD PMID:16417649 NCBI chr 1:46,247,688...46,278,473
Ensembl chr 1:46,246,461...46,278,480 		JBrowse link
G RASIP1 Ras interacting protein 1 affects response to substance EXP RASIP1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr19:48,720,585...48,740,610
Ensembl chr19:48,720,585...48,740,610 		JBrowse link
G RASSF1 Ras association domain family member 1 multiple interactions
increases response to substance		 EXP [RASSF1 co-treated with Etoposide] affects the folding of and results in increased activity of BAX protein; [RASSF1 co-treated with Etoposide] results in increased cleavage of CASP3 protein; [RASSF1 co-treated with Etoposide] results in increased expression of CDKN1A protein; ABT-737 promotes the reaction [RASSF1 results in increased susceptibility to Etoposide] CTD PMID:21880625 NCBI chr 3:50,329,788...50,340,836
Ensembl chr 3:50,329,782...50,340,980 		JBrowse link
G RB1 RB transcriptional corepressor 1 affects response to substance
decreases phosphorylation
multiple interactions		 EXP RB1 protein affects the susceptibility to Etoposide
Etoposide results in decreased phosphorylation of RB1 protein
[Colforsin co-treated with Theophylline] inhibits the reaction [Etoposide results in decreased phosphorylation of RB1 protein]		 CTD PMID:9454737 PMID:17640669 NCBI chr13:48,303,751...48,481,890
Ensembl chr13:48,303,744...48,599,436 		JBrowse link
G RBM17 RNA binding motif protein 17 decreases response to substance EXP RBM17 protein results in decreased susceptibility to Etoposide CTD PMID:16061639 NCBI chr10:6,089,034...6,117,447
Ensembl chr10:6,089,034...6,117,457 		JBrowse link
G RBM34 RNA binding motif protein 34 decreases expression EXP Etoposide results in decreased expression of RBM34 mRNA CTD PMID:24211769 NCBI chr 1:235,131,183...235,161,250
Ensembl chr 1:235,131,183...235,161,283 		JBrowse link
G RCAN1 regulator of calcineurin 1 affects response to substance EXP RCAN1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr21:34,516,442...34,615,113
Ensembl chr21:34,513,142...34,615,113 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit multiple interactions EXP [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of BCL2L1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in decreased susceptibility to Etoposide; resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in decreased susceptibility to Etoposide] CTD PMID:19047049 NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090 		JBrowse link
G RETSAT retinol saturase increases expression EXP Etoposide results in increased expression of RETSAT mRNA CTD PMID:21527772 NCBI chr 2:85,341,955...85,354,528
Ensembl chr 2:85,341,955...85,354,531 		JBrowse link
G RFC1 replication factor C subunit 1 decreases expression EXP Etoposide results in decreased expression of RFC1 mRNA CTD PMID:24211769 NCBI chr 4:39,287,456...39,366,362
Ensembl chr 4:39,287,456...39,366,375 		JBrowse link
G RGCC regulator of cell cycle increases expression EXP Etoposide results in increased expression of RGCC mRNA CTD PMID:29397400 NCBI chr13:41,457,550...41,470,871
Ensembl chr13:41,457,550...41,470,871 		JBrowse link
G RIPK2 receptor interacting serine/threonine kinase 2 multiple interactions
increases expression		 EXP Estradiol inhibits the reaction [Etoposide results in increased expression of RIPK2 mRNA] CTD PMID:19426747 NCBI chr 8:89,757,816...89,791,064
Ensembl chr 8:89,757,806...89,791,064 		JBrowse link
G RIPPLY3 ripply transcriptional repressor 3 increases expression EXP Etoposide results in increased expression of RIPPLY3 mRNA CTD PMID:21527772 NCBI chr21:37,006,150...37,019,662
Ensembl chr21:37,006,150...37,019,662 		JBrowse link
G RNF113A ring finger protein 113A decreases expression EXP Etoposide results in decreased expression of RNF113A mRNA CTD PMID:24211769 NCBI chr  X:119,870,475...119,871,733
Ensembl chr  X:119,870,475...119,871,733 		JBrowse link
G ROBO1 roundabout guidance receptor 1 affects response to substance EXP ROBO1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 3:78,597,239...79,767,998
Ensembl chr 3:78,597,239...79,767,998 		JBrowse link
G ROBO3 roundabout guidance receptor 3 increases expression EXP Etoposide results in increased expression of ROBO3 mRNA CTD PMID:21527772 NCBI chr11:124,865,432...124,881,471
Ensembl chr11:124,865,432...124,881,471 		JBrowse link
G ROPN1 rhophilin associated tail protein 1 affects response to substance EXP ROPN1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 3:123,969,015...123,992,124
Ensembl chr 3:123,968,521...123,992,178 		JBrowse link
G RPL6 ribosomal protein L6 decreases response to substance EXP RPL6 protein results in decreased susceptibility to Etoposide CTD PMID:15846068 NCBI chr12:112,405,181...112,418,835
Ensembl chr12:112,405,189...112,418,838 		JBrowse link
G RPS27L ribosomal protein S27 like increases expression EXP Etoposide results in increased expression of RPS27L protein CTD PMID:18056458 NCBI chr15:63,148,249...63,157,477
Ensembl chr15:63,125,872...63,158,021 		JBrowse link
G RPS6 ribosomal protein S6 increases phosphorylation EXP Etoposide results in increased phosphorylation of RPS6 protein CTD PMID:23396362 NCBI chr 9:19,375,715...19,380,236
Ensembl chr 9:19,375,715...19,380,236 		JBrowse link
G RRAS RAS related increases expression EXP Etoposide results in increased expression of RRAS mRNA CTD PMID:21527772 NCBI chr19:49,635,292...49,640,143
Ensembl chr19:49,635,292...49,640,143 		JBrowse link
G RRM2B ribonucleotide reductase regulatory TP53 inducible subunit M2B increases expression EXP Etoposide results in increased expression of RRM2B mRNA CTD PMID:21704725 NCBI chr 8:102,204,501...102,238,961
Ensembl chr 8:102,204,502...102,238,961 		JBrowse link
G RTKN rhotekin increases expression ISO Etoposide results in increased expression of RTKN mRNA CTD PMID:25270620 NCBI chr 2:74,425,835...74,441,937
Ensembl chr 2:74,425,835...74,442,422 		JBrowse link
G RUNX1 RUNX family transcription factor 1 increases response to substance
increases mutagenesis		 EXP RUNX1 gene mutant form results in increased susceptibility to Etoposide
Etoposide results in increased mutagenesis of RUNX1 gene		 CTD PMID:15217836 PMID:28624474 NCBI chr21:34,787,801...35,049,302
Ensembl chr21:34,787,801...36,004,667 		JBrowse link
G RUNX3 RUNX family transcription factor 3 increases response to substance EXP RUNX3 protein results in increased susceptibility to Etoposide CTD PMID:15756676 NCBI chr 1:24,899,511...24,965,138
Ensembl chr 1:24,899,511...24,965,121 		JBrowse link
G RXRA retinoid X receptor alpha multiple interactions EXP Etoposide promotes the reaction [RXRA protein results in increased expression of CETP mRNA]; Tretinoin promotes the reaction [Etoposide promotes the reaction [RXRA protein results in increased expression of CETP mRNA]] CTD PMID:25914138 NCBI chr 9:134,326,455...134,440,585
Ensembl chr 9:134,317,098...134,440,585 		JBrowse link
G RYR2 ryanodine receptor 2 decreases expression EXP Etoposide results in decreased expression of RYR2 mRNA CTD PMID:29397400 NCBI chr 1:237,042,184...237,833,988
Ensembl chr 1:237,042,184...237,833,988 		JBrowse link
G S100P S100 calcium binding protein P affects response to substance
increases response to substance		 EXP S100P protein affects the susceptibility to Etoposide
S100P protein results in increased susceptibility to Etoposide		 CTD PMID:16217747 PMID:18636193 NCBI chr 4:6,693,878...6,697,170
Ensembl chr 4:6,693,878...6,697,170 		JBrowse link
G SCN3B sodium voltage-gated channel beta subunit 3 increases expression ISO Etoposide results in increased expression of SCN3B mRNA CTD PMID:25270620 NCBI chr11:123,629,188...123,654,624
Ensembl chr11:123,629,187...123,655,244 		JBrowse link
G SCN4B sodium voltage-gated channel beta subunit 4 increases expression EXP Etoposide results in increased expression of SCN4B mRNA CTD PMID:29397400 NCBI chr11:118,133,377...118,152,823
Ensembl chr11:118,133,377...118,152,888 		JBrowse link
G SDC1 syndecan 1 increases expression EXP Etoposide results in increased expression of SDC1 mRNA CTD PMID:17374387 NCBI chr 2:20,200,797...20,225,475
Ensembl chr 2:20,200,797...20,225,433 		JBrowse link
G SDHAF1 succinate dehydrogenase complex assembly factor 1 decreases expression EXP Etoposide results in decreased expression of SDHAF1 mRNA CTD PMID:24211769 NCBI chr19:35,995,188...35,996,312
Ensembl chr19:35,995,188...35,996,312 		JBrowse link
G SERPINE2 serpin family E member 2 increases expression ISO Etoposide results in increased expression of SERPINE2 mRNA CTD PMID:25270620 NCBI chr 2:223,975,045...224,039,286
Ensembl chr 2:223,975,045...224,039,318 		JBrowse link
G SESN1 sestrin 1 increases expression EXP Etoposide results in increased expression of SESN1 mRNA CTD PMID:24211769 NCBI chr 6:108,984,309...109,094,846
Ensembl chr 6:108,984,309...109,094,846 		JBrowse link
G SFN stratifin increases expression EXP Etoposide results in increased expression of SFN mRNA CTD PMID:21527772 NCBI chr 1:26,863,149...26,864,456
Ensembl chr 1:26,863,149...26,864,456 		JBrowse link
G SLBP stem-loop histone mRNA binding protein decreases expression EXP Etoposide results in decreased expression of SLBP mRNA CTD PMID:24211769 NCBI chr 4:1,692,731...1,712,319
Ensembl chr 4:1,692,731...1,712,344 		JBrowse link
G SLC16A6 solute carrier family 16 member 6 affects response to substance EXP SLC16A6 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr17:68,267,026...68,291,479
Ensembl chr17:68,267,026...68,291,267 		JBrowse link
G SLC1A5 solute carrier family 1 member 5 decreases expression EXP Etoposide results in decreased expression of SLC1A5 mRNA CTD PMID:24211769 NCBI chr19:46,774,883...46,788,594
Ensembl chr19:46,774,883...46,788,594 		JBrowse link
G SLC22A18 solute carrier family 22 member 18 affects response to substance EXP SLC22A18 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr11:2,899,691...2,925,246
Ensembl chr11:2,899,721...2,925,246 		JBrowse link
G SLC27A3 solute carrier family 27 member 3 affects response to substance EXP SLC27A3 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 1:153,775,407...153,780,157
Ensembl chr 1:153,774,354...153,780,157 		JBrowse link
G SLC2A6 solute carrier family 2 member 6 increases expression EXP Etoposide results in increased expression of SLC2A6 mRNA CTD PMID:21527772 NCBI chr 9:133,471,094...133,479,099
Ensembl chr 9:133,471,094...133,479,127 		JBrowse link
G SLC35F2 solute carrier family 35 member F2 decreases expression ISO Etoposide results in decreased expression of SLC35F2 mRNA CTD PMID:25270620 NCBI chr11:107,790,991...107,858,787
Ensembl chr11:107,790,991...107,928,293 		JBrowse link
G SLC45A3 solute carrier family 45 member 3 multiple interactions EXP Etoposide inhibits the reaction [Dihydrotestosterone results in increased expression of SLC45A3 mRNA] CTD PMID:20601956 NCBI chr 1:205,657,851...205,680,509
Ensembl chr 1:205,657,851...205,680,509 		JBrowse link
G SLC4A11 solute carrier family 4 member 11 increases expression ISO Etoposide results in increased expression of SLC4A11 mRNA CTD PMID:25270620 NCBI chr20:3,227,417...3,239,559
Ensembl chr20:3,227,417...3,239,559 		JBrowse link
G SLC7A11 solute carrier family 7 member 11 affects response to substance EXP SLC7A11 protein affects the susceptibility to Etoposide CTD PMID:31226288 NCBI chr 4:138,164,097...138,312,671
Ensembl chr 4:138,164,097...138,242,349 		JBrowse link
G SLC7A3 solute carrier family 7 member 3 decreases expression ISO Etoposide results in decreased expression of SLC7A3 mRNA CTD PMID:25270620 NCBI chr  X:70,925,579...70,931,096
Ensembl chr  X:70,925,579...70,931,125 		JBrowse link
G SLC7A5 solute carrier family 7 member 5 affects response to substance EXP SLC7A5 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr16:87,830,023...87,869,507
Ensembl chr16:87,830,023...87,869,507 		JBrowse link
G SLC8A1 solute carrier family 8 member A1 decreases expression EXP Etoposide results in decreased expression of SLC8A1 mRNA CTD PMID:29397400 NCBI chr 2:40,097,270...40,512,435
Ensembl chr 2:40,097,270...40,611,053 		JBrowse link
G SLCO2B1 solute carrier organic anion transporter family member 2B1 multiple interactions EXP Etoposide inhibits the reaction [SLCO2B1 protein results in increased uptake of Cascade Blue] CTD PMID:30863990 NCBI chr11:75,151,107...75,206,549
Ensembl chr11:75,100,563...75,206,549 		JBrowse link
G SMAD2 SMAD family member 2 multiple interactions
increases phosphorylation		 EXP 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [Etoposide results in increased phosphorylation of SMAD2 protein] CTD PMID:22363485 NCBI chr18:47,808,957...47,930,872
Ensembl chr18:47,808,957...47,931,146 		JBrowse link
G SMPDL3A sphingomyelin phosphodiesterase acid like 3A affects response to substance EXP SMPDL3A protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 6:122,789,258...122,809,720
Ensembl chr 6:122,789,049...122,809,720 		JBrowse link
G SOD2 superoxide dismutase 2 increases expression
decreases response to substance		 EXP Etoposide results in increased expression of SOD2 protein
SOD2 protein results in decreased susceptibility to Etoposide		 CTD PMID:10759716 NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529 		JBrowse link
G SOHLH1 spermatogenesis and oogenesis specific basic helix-loop-helix 1 decreases expression ISO Etoposide results in decreased expression of SOHLH1 mRNA CTD PMID:29733421 NCBI chr 9:135,693,407...135,702,112
Ensembl chr 9:135,693,407...135,704,498 		JBrowse link
G SORBS1 sorbin and SH3 domain containing 1 affects response to substance EXP SORBS1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr10:95,311,773...95,561,371
Ensembl chr10:95,311,771...95,561,414 		JBrowse link
G SORBS2 sorbin and SH3 domain containing 2 affects response to substance EXP SORBS2 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 4:185,585,523...185,956,372
Ensembl chr 4:185,585,444...185,956,652 		JBrowse link
G SORT1 sortilin 1 affects response to substance EXP SORT1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 1:109,309,575...109,397,918
Ensembl chr 1:109,309,568...109,397,918 		JBrowse link
G SOX10 SRY-box transcription factor 10 affects response to substance EXP SOX10 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr22:37,972,312...37,984,555
Ensembl chr22:37,970,686...37,987,422 		JBrowse link
G SOX2 SRY-box transcription factor 2 multiple interactions EXP FTL protein affects the reaction [Etoposide results in increased expression of SOX2 protein] CTD PMID:33969609 NCBI chr 3:181,711,925...181,714,436
Ensembl chr 3:181,711,925...181,714,436 		JBrowse link
G SP1 Sp1 transcription factor increases phosphorylation
increases expression
increases activity
multiple interactions		 EXP
ISO		 Etoposide results in increased phosphorylation of SP1 protein
Etoposide results in increased expression of SP1 mRNA
Etoposide results in increased activity of SP1 protein
cordycepin inhibits the reaction [Etoposide results in increased activity of SP1 protein]; cordycepin inhibits the reaction [Etoposide results in increased expression of SP1 mRNA]
PRKDC protein promotes the reaction [Etoposide results in increased phosphorylation of SP1 protein]; wortmannin inhibits the reaction [Etoposide results in increased phosphorylation of SP1 protein]		 CTD PMID:17441964 PMID:23690541 NCBI chr12:53,380,176...53,416,446
Ensembl chr12:53,380,176...53,416,446 		JBrowse link
G SPATA18 spermatogenesis associated 18 increases expression EXP Etoposide results in increased expression of SPATA18 mRNA CTD PMID:21527772 PMID:29397400 NCBI chr 4:52,051,304...52,097,299
Ensembl chr 4:52,051,304...52,097,299 		JBrowse link
G SPP1 secreted phosphoprotein 1 affects response to substance
decreases expression		 EXP
ISO		 SPP1 protein affects the susceptibility to Etoposide
Etoposide results in decreased expression of SPP1 mRNA		 CTD PMID:16217747 PMID:25270620 NCBI chr 4:87,975,714...87,983,411
Ensembl chr 4:87,975,667...87,983,532 		JBrowse link
G SPTSSA serine palmitoyltransferase small subunit A affects response to substance EXP SPTSSA protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr14:34,432,788...34,462,240
Ensembl chr14:34,432,788...34,462,240 		JBrowse link
G SRXN1 sulfiredoxin 1 increases expression
multiple interactions		 ISO
EXP		 Etoposide results in increased expression of SRXN1 mRNA; Etoposide results in increased expression of SRXN1 protein
NFE2L2 protein affects the reaction [Etoposide results in increased expression of SRXN1 protein]; TP53 protein affects the reaction [Etoposide results in increased expression of SRXN1 protein]		 CTD PMID:22003191 PMID:27358234 PMID:27982581 NCBI chr20:646,615...653,200
Ensembl chr20:646,615...653,200 		JBrowse link
G ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 decreases response to substance ISO ST3GAL5 protein results in decreased susceptibility to Etoposide CTD PMID:16571667 NCBI chr 2:85,837,120...85,889,034
Ensembl chr 2:85,837,120...85,905,199 		JBrowse link
G ST6GALNAC2 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 affects response to substance EXP ST6GALNAC2 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr17:76,565,377...76,585,860
Ensembl chr17:76,565,377...76,586,956 		JBrowse link
G ST7 suppression of tumorigenicity 7 affects response to substance EXP ST7 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 7:116,953,501...117,230,176
Ensembl chr 7:116,953,238...117,230,176 		JBrowse link
G STAT1 signal transducer and activator of transcription 1 multiple interactions EXP [STAT1 protein results in increased activity of CASP3 protein] which results in increased susceptibility to Etoposide; [STAT1 protein results in increased activity of CASP7 protein] which results in increased susceptibility to Etoposide CTD PMID:18649362 NCBI chr 2:190,969,149...191,014,171
Ensembl chr 2:190,908,460...191,020,960 		JBrowse link
G STC1 stanniocalcin 1 increases expression EXP Etoposide results in increased expression of STC1 mRNA CTD PMID:29397400 NCBI chr 8:23,841,929...23,854,806
Ensembl chr 8:23,841,929...23,854,806 		JBrowse link
G STIP1 stress induced phosphoprotein 1 increases expression ISO Etoposide results in increased expression of STIP1 protein CTD PMID:29733421 NCBI chr11:64,185,272...64,204,543
Ensembl chr11:64,185,272...64,204,543 		JBrowse link
G STK17A serine/threonine kinase 17a increases expression ISO Etoposide results in increased expression of STK17A mRNA CTD PMID:21489989 NCBI chr 7:43,583,108...43,627,379
Ensembl chr 7:43,582,758...43,650,713 		JBrowse link
G STMN1 stathmin 1 affects response to substance EXP STMN1 affects the susceptibility to Etoposide CTD PMID:17172428 NCBI chr 1:25,884,179...25,906,880
Ensembl chr 1:25,884,181...25,906,991 		JBrowse link
G STMN2 stathmin 2 decreases expression ISO Etoposide results in decreased expression of STMN2 mRNA CTD PMID:25270620 NCBI chr 8:79,611,117...79,666,158
Ensembl chr 8:79,611,117...79,666,158 		JBrowse link
G STOM stomatin increases expression EXP Etoposide results in increased expression of STOM mRNA CTD PMID:21527772 NCBI chr 9:121,338,987...121,370,250
Ensembl chr 9:121,338,987...121,370,304 		JBrowse link
G SYTL1 synaptotagmin like 1 increases expression ISO Etoposide results in increased expression of SYTL1 mRNA CTD PMID:25270620 NCBI chr 1:27,342,022...27,353,932
Ensembl chr 1:27,342,020...27,353,937 		JBrowse link
G TAP1 transporter 1, ATP binding cassette subfamily B member increases expression EXP Etoposide results in increased expression of TAP1 mRNA CTD PMID:17374387 PMID:21527772 NCBI chr 6:32,845,209...32,853,704
Ensembl chr 6:32,845,209...32,853,816 		JBrowse link
G TAX1BP3 Tax1 binding protein 3 increases expression EXP Etoposide results in increased expression of TAX1BP3 mRNA CTD PMID:17374387 NCBI chr17:3,662,895...3,668,578
Ensembl chr17:3,662,895...3,668,679 		JBrowse link
G TBC1D8 TBC1 domain family member 8 increases expression ISO Etoposide results in increased expression of TBC1D8 mRNA CTD PMID:25270620 NCBI chr 2:101,007,228...101,151,382
Ensembl chr 2:101,007,228...101,252,866 		JBrowse link
G TBL1X transducin beta like 1 X-linked decreases expression ISO Etoposide results in decreased expression of TBL1X mRNA CTD PMID:25270620 NCBI chr  X:9,463,295...9,719,740
Ensembl chr  X:9,463,320...9,741,037 		JBrowse link
G TBPL1 TATA-box binding protein like 1 affects localization ISO Etoposide affects the localization of TBPL1 protein CTD PMID:17085973 NCBI chr 6:133,952,174...133,990,432
Ensembl chr 6:133,952,170...133,990,432 		JBrowse link
G TCAP titin-cap decreases expression EXP Etoposide results in decreased expression of TCAP mRNA CTD PMID:29397400 NCBI chr17:39,665,349...39,666,554
Ensembl chr17:39,665,349...39,666,554 		JBrowse link
G TCFL5 transcription factor like 5 affects response to substance EXP TCFL5 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr20:62,841,005...62,861,822
Ensembl chr20:62,841,005...62,861,822 		JBrowse link
G TCP1 t-complex 1 multiple interactions ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of TCP1 protein CTD PMID:29733421 NCBI chr 6:159,778,498...159,789,602
Ensembl chr 6:159,778,498...159,789,703 		JBrowse link
G TDRD3 tudor domain containing 3 affects response to substance EXP TDRD3 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr13:60,395,533...60,573,879
Ensembl chr13:60,396,457...60,573,878 		JBrowse link
G TENT5A terminal nucleotidyltransferase 5A affects response to substance EXP TENT5A protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 6:81,745,730...81,752,681
Ensembl chr 6:81,491,439...81,752,774 		JBrowse link
G TEX264 testis expressed 264, ER-phagy receptor decreases expression ISO Etoposide results in decreased expression of TEX264 mRNA CTD PMID:25270620 NCBI chr 3:51,671,252...51,704,323
Ensembl chr 3:51,662,693...51,704,323 		JBrowse link
G TFAM transcription factor A, mitochondrial increases expression EXP Etoposide results in increased expression of TFAM mRNA CTD PMID:26259609 NCBI chr10:58,385,410...58,399,220
Ensembl chr10:58,385,345...58,399,220 		JBrowse link
G TFAP2A transcription factor AP-2 alpha affects response to substance
increases response to substance		 EXP TFAP2A protein affects the susceptibility to Etoposide
TFAP2A protein results in increased susceptibility to Etoposide		 CTD PMID:16204029 PMID:16217747 NCBI chr 6:10,396,677...10,419,659
Ensembl chr 6:10,393,186...10,419,659 		JBrowse link
G TFEC transcription factor EC decreases expression EXP Etoposide results in decreased expression of TFEC mRNA CTD PMID:24211769 NCBI chr 7:115,935,152...116,159,896
Ensembl chr 7:115,935,148...116,159,896 		JBrowse link
G TFF3 trefoil factor 3 affects response to substance EXP TFF3 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr21:42,311,667...42,315,409
Ensembl chr21:42,311,667...42,315,409 		JBrowse link
G TFPI tissue factor pathway inhibitor affects response to substance EXP TFPI protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 2:187,464,230...187,554,435
Ensembl chr 2:187,464,230...187,565,760 		JBrowse link
G TFPI2 tissue factor pathway inhibitor 2 affects response to substance EXP TFPI2 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 7:93,885,396...93,890,753
Ensembl chr 7:93,885,396...93,890,753 		JBrowse link
G TFRC transferrin receptor decreases expression
multiple interactions		 EXP Etoposide results in decreased expression of TFRC mRNA; Etoposide results in decreased expression of TFRC protein
1-cyclopropyl-4-(4-((5-methyl-3-(3-(4-(trifluoromethoxy)phenyl)-1,2,4-oxadiazol-5-yl)-1H-pyrazol-1-yl)methyl)pyridin-2-yl)piperazine inhibits the reaction [Etoposide results in decreased expression of TFRC protein]		 CTD PMID:33969609 NCBI chr 3:196,049,284...196,082,090
Ensembl chr 3:196,012,511...196,082,153 		JBrowse link
G TGDS TDP-glucose 4,6-dehydratase affects response to substance EXP TGDS protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr13:94,574,054...94,596,273
Ensembl chr13:94,574,054...94,596,242 		JBrowse link
G TGFA transforming growth factor alpha increases expression EXP Etoposide results in increased expression of TGFA mRNA CTD PMID:15228094 NCBI chr 2:70,447,284...70,553,826
Ensembl chr 2:70,447,284...70,554,193 		JBrowse link
G TGIF2 TGFB induced factor homeobox 2 decreases expression ISO Etoposide results in decreased expression of TGIF2 mRNA CTD PMID:25270620 NCBI chr20:36,573,464...36,593,950
Ensembl chr20:36,573,488...36,593,950 		JBrowse link
G THBS4 thrombospondin 4 increases expression EXP Etoposide results in increased expression of THBS4 mRNA CTD PMID:29397400 NCBI chr 5:79,991,332...80,083,287
Ensembl chr 5:79,991,311...80,083,287 		JBrowse link
G TIPIN TIMELESS interacting protein decreases expression EXP Etoposide results in decreased expression of TIPIN mRNA CTD PMID:24211769 NCBI chr15:66,336,191...66,386,717
Ensembl chr15:66,336,191...66,386,746 		JBrowse link
G TM7SF3 transmembrane 7 superfamily member 3 increases expression ISO Etoposide results in increased expression of TM7SF3 mRNA CTD PMID:25270620 NCBI chr12:26,971,579...27,014,384
Ensembl chr12:26,971,579...27,014,434 		JBrowse link
G TMBIM4 transmembrane BAX inhibitor motif containing 4 increases expression ISO Etoposide results in increased expression of TMBIM4 mRNA CTD PMID:25270620 NCBI chr12:66,135,846...66,169,996
Ensembl chr12:66,135,846...66,170,027 		JBrowse link
G TMC6 transmembrane channel like 6 affects response to substance EXP TMC6 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr17:78,107,397...78,132,427
Ensembl chr17:78,107,397...78,132,407 		JBrowse link
G TMEM185B transmembrane protein 185B decreases expression EXP Etoposide results in decreased expression of TMEM185B mRNA CTD PMID:24211769 NCBI chr 2:120,217,479...120,223,400
Ensembl chr 2:120,217,479...120,223,400 		JBrowse link
G TMEM204 transmembrane protein 204 decreases expression ISO Etoposide results in decreased expression of TMEM204 mRNA CTD PMID:25270620 NCBI chr16:1,528,678...1,555,568
Ensembl chr16:1,528,688...1,555,580 		JBrowse link
G TMEM47 transmembrane protein 47 affects response to substance EXP TMEM47 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr  X:34,627,075...34,657,285
Ensembl chr  X:34,627,075...34,657,285 		JBrowse link
G TMEM97 transmembrane protein 97 affects response to substance EXP TMEM97 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr17:28,319,200...28,328,685
Ensembl chr17:28,319,200...28,328,685 		JBrowse link
G TMPRSS2 transmembrane serine protease 2 multiple interactions EXP Etoposide inhibits the reaction [Dihydrotestosterone results in increased expression of TMPRSS2 mRNA] CTD PMID:20601956 NCBI chr21:41,464,305...41,508,158
Ensembl chr21:41,464,300...41,531,116 		JBrowse link
G TMSB4X thymosin beta 4 X-linked multiple interactions
decreases response to substance		 EXP TMSB4X protein inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; TMSB4X protein inhibits the reaction [Etoposide results in increased cleavage of and results in increased activity of CASP9 protein]
TMSB4X protein results in decreased susceptibility to Etoposide		 CTD PMID:16364925 NCBI chr  X:12,975,110...12,977,223
Ensembl chr  X:12,975,110...12,977,227 		JBrowse link
G TNF tumor necrosis factor increases expression ISO Etoposide results in increased expression of TNF mRNA CTD PMID:15135310 PMID:18523641 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TNFRSF10B TNF receptor superfamily member 10b multiple interactions
increases expression		 EXP Etoposide promotes the reaction [TP53 protein binds to TNFRSF10B promoter]
Etoposide results in increased expression of TNFRSF10B mRNA		 CTD PMID:15964798 NCBI chr 8:23,020,133...23,069,031
Ensembl chr 8:23,020,133...23,069,031 		JBrowse link
G TNFRSF11B TNF receptor superfamily member 11b increases expression ISO Etoposide results in increased expression of TNFRSF11B mRNA CTD PMID:11459812 NCBI chr 8:118,923,557...118,951,885
Ensembl chr 8:118,923,557...118,951,885 		JBrowse link
G TNFRSF12A TNF receptor superfamily member 12A multiple interactions
increases expression		 EXP Estradiol inhibits the reaction [Etoposide results in increased expression of TNFRSF12A mRNA] CTD PMID:19426747 NCBI chr16:3,020,368...3,022,383
Ensembl chr16:3,018,445...3,022,383 		JBrowse link
G TNFRSF14 TNF receptor superfamily member 14 increases expression EXP Etoposide results in increased expression of TNFRSF14 mRNA CTD PMID:21527772 NCBI chr 1:2,554,234...2,563,829
Ensembl chr 1:2,555,639...2,565,382 		JBrowse link
G TNFRSF1A TNF receptor superfamily member 1A affects response to substance ISO TNFRSF1A protein affects the susceptibility to Etoposide CTD PMID:20159942 NCBI chr12:6,328,771...6,342,076
Ensembl chr12:6,328,757...6,342,114 		JBrowse link
G TNFSF11 TNF superfamily member 11 decreases expression ISO Etoposide results in decreased expression of TNFSF11 mRNA CTD PMID:11459812 NCBI chr13:42,562,736...42,608,013
Ensembl chr13:42,562,736...42,608,013 		JBrowse link
G TNFSF9 TNF superfamily member 9 increases expression EXP Etoposide results in increased expression of TNFSF9 mRNA CTD PMID:17374387 NCBI chr19:6,531,026...6,535,924
Ensembl chr19:6,531,026...6,535,924 		JBrowse link
G TNKS tankyrase affects response to substance EXP TNKS protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 8:9,555,912...9,782,346
Ensembl chr 8:9,555,912...9,782,346 		JBrowse link
G TOP2A DNA topoisomerase II alpha affects binding
decreases activity
multiple interactions
affects activity
decreases expression
increases response to substance
affects response to substance
decreases response to substance		 EXP
ISO		 Etoposide binds to TOP2A protein
Etoposide analog results in decreased activity of TOP2A protein; Etoposide metabolite results in decreased activity of TOP2A protein; Etoposide results in decreased activity of TOP2A protein
[Ciprofloxacin binds to TOP2A protein] inhibits the reaction [Etoposide binds to TOP2A protein]; [EGF protein results in decreased expression of TOP2A protein] which results in decreased susceptibility to Etoposide; [MAPK12 protein results in increased phosphorylation of TOP2A protein] which results in increased susceptibility to Etoposide; [MAPK12 protein results in increased stability of TOP2A protein] which results in increased susceptibility to Etoposide; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Etoposide promotes the reaction [MDM2 protein binds to TOP2A protein]]; delphinidin results in decreased susceptibility to [Etoposide affects the activity of TOP2A protein]; Etoposide metabolite inhibits the reaction [TOP2A protein binds to Nucleic Acids, Nucleotides, and Nucleosides]; Etoposide metabolite inhibits the reaction [TOP2A protein results in increased hydrolysis of Adenosine Triphosphate]; Etoposide promotes the reaction [MDM2 protein binds to TOP2A protein]; TOP2A results in decreased susceptibility to [Carboplatin co-treated with Etoposide co-treated with Ifosfamide]; TOP2A results in decreased susceptibility to [Cisplatin co-treated with Etoposide]
Etoposide results in decreased expression of TOP2A protein
TOP2A protein results in increased susceptibility to Etoposide
TOP2A protein modified form affects the susceptibility to Etoposide
TOP2A gene mutant form results in decreased susceptibility to Etoposide; TOP2A protein mutant form results in decreased susceptibility to Etoposide		 CTD PMID:10856430 PMID:11325482 PMID:11470519 PMID:11531262 PMID:11676865 More... NCBI chr17:40,388,525...40,417,896
Ensembl chr17:40,388,525...40,417,896 		JBrowse link
G TOP2B DNA topoisomerase II beta decreases response to substance
decreases activity
affects response to substance
decreases expression
multiple interactions
increases response to substance		 EXP
ISO		 TOP2B protein mutant form results in decreased susceptibility to Etoposide
Etoposide results in decreased activity of TOP2B protein
TOP2B protein affects the susceptibility to Etoposide
Etoposide results in decreased expression of TOP2B protein
TOP2B protein affects the reaction [Etoposide results in increased expression of H2AX protein]
TOP2B protein mutant form results in increased susceptibility to Etoposide		 CTD PMID:10856430 PMID:15322234 PMID:16239602 PMID:17875725 PMID:26198043 More... NCBI chr 3:25,597,905...25,664,907
Ensembl chr 3:25,597,978...25,664,909 		JBrowse link
G TOP3A DNA topoisomerase III alpha decreases expression EXP Etoposide results in decreased expression of TOP3A mRNA CTD PMID:24211769 NCBI chr17:18,271,428...18,314,994
Ensembl chr17:18,271,428...18,315,007 		JBrowse link
G TOR1A torsin family 1 member A decreases expression EXP Etoposide results in decreased expression of TOR1A mRNA CTD PMID:24211769 NCBI chr 9:129,812,942...129,824,136
Ensembl chr 9:129,812,942...129,824,244 		JBrowse link
G TP53 tumor protein p53 increases acetylation
affects activity
increases expression
multiple interactions
increases activity
increases phosphorylation
affects response to substance
increases response to substance		 EXP
ISO		 Etoposide results in increased acetylation of TP53 protein; Etoposide results in increased acetylation of TP53 protein mutant form
Etoposide affects the activity of TP53 protein; Etoposide metabolite affects the activity of TP53 protein
Etoposide results in increased expression of TRP53 protein
[CDKN2A gene mutant form results in increased expression of CDKN2A protein alternative form] inhibits the reaction [Etoposide results in increased expression of TRP53 protein]; Etoposide results in increased phosphorylation of and results in increased activity of TRP53 protein; TRP53 affects the reaction [Etoposide results in increased expression of CDKN1A mRNA]; TRP53 affects the reaction [Etoposide results in increased expression of TPT1 mRNA]; TRP53 affects the reaction [Etoposide results in increased expression of TPT1 protein]; TRP53 protein affects the reaction [Etoposide results in increased expression of BTG2 mRNA]
Etoposide results in increased activity of TP53 protein
Etoposide results in increased phosphorylation of TP53 protein
TRP53 protein affects the susceptibility to Etoposide
2,4,4'-trichlorobiphenyl inhibits the reaction [Etoposide results in increased expression of TP53 protein]; 2,4,5,2',5'-pentachlorobiphenyl inhibits the reaction [Etoposide results in increased expression of TP53 protein]; 3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [Etoposide results in increased expression of TP53 protein]; [CASP8 co-treated with TP53] affects the reaction [Etoposide results in increased cleavage of and results in increased activity of CASP9 protein]; [CASP8 co-treated with TP53] affects the reaction [Etoposide results in increased cleavage of CASP3 protein]; [CASP8 co-treated with TP53] affects the reaction [Etoposide results in increased cleavage of PARP1 protein]; [CASP8 co-treated with TP53] inhibits the reaction [CASP8 protein mutant form results in decreased susceptibility to Etoposide]; [Doxorubicin co-treated with Vincristine co-treated with Etoposide co-treated with Mitotane] results in decreased expression of TP53 protein; [Etoposide results in increased acetylation of TP53 protein mutant form] which results in increased expression of UBE2C protein; [TP53 protein results in increased susceptibility to Etoposide] which results in decreased chemical synthesis of benzo(a)pyrene 7,8-dihydrodiol; Cadmium Chloride affects the reaction [Etoposide results in increased phosphorylation of TP53 protein]; DAPK1 protein promotes the reaction [Etoposide results in increased expression of TP53 protein modified form]; DAPK1 protein promotes the reaction [Etoposide results in increased expression of TP53 protein]; entinostat promotes the reaction [Etoposide results in increased expression of and results in increased acetylation of TP53 protein]; Etoposide promotes the reaction [[TP53 protein binds to GDF15 promoter] which results in increased expression of GDF15 mRNA]; Etoposide promotes the reaction [entinostat results in increased expression of TP53 protein]; Etoposide promotes the reaction [TP53 protein binds to TNFRSF10B promoter]; Etoposide promotes the reaction [TP53 protein results in increased chemical synthesis of benzo(a)pyrene 7,8-dihydrodiol]; Etoposide promotes the reaction [trichostatin A results in increased expression of TP53 protein]; Etoposide promotes the reaction [UF010 compound results in increased expression of TP53 protein]; Etoposide results in increased expression of and results in increased acetylation of TP53 protein; Etoposide results in increased phosphorylation of and affects the localization of TP53 protein; Etoposide results in increased phosphorylation of and results in increased activity of TP53 protein; NFE2L2 protein affects the reaction [Etoposide results in increased expression of TP53 protein]; NFKB1 protein affects the reaction [Etoposide results in increased expression of TP53 protein]; Oxygen deficiency inhibits the reaction [Etoposide results in increased phosphorylation of TP53 protein]; pifithrin inhibits the reaction [Etoposide results in increased activity of TP53 protein]; Tetrachlorodibenzodioxin inhibits the reaction [Etoposide results in increased acetylation of TP53 protein]; Tetrachlorodibenzodioxin inhibits the reaction [Etoposide results in increased phosphorylation of and results in increased activity of TP53 protein]; TP53 affects the reaction [Etoposide results in increased expression of CDKN1A mRNA]; TP53 affects the reaction [Etoposide results in increased expression of TPT1 mRNA]; TP53 promotes the reaction [Etoposide results in increased expression of BTG2 protein]; TP53 promotes the reaction [Etoposide results in increased expression of CDKN1A protein]; TP53 protein affects the reaction [CHEK1 protein affects the susceptibility to Etoposide]; TP53 protein affects the reaction [Etoposide results in decreased expression of UBE2C mRNA]; TP53 protein affects the reaction [Etoposide results in increased expression of SRXN1 protein]; TP53 protein inhibits the reaction [ESR2 protein results in increased susceptibility to Etoposide]; TP53 protein inhibits the reaction [Etoposide results in decreased expression of UBE2C protein]; TP53 protein modified form inhibits the reaction [Etoposide results in increased expression of BBC3 protein]; TP53 protein promotes the reaction [[Etoposide results in increased susceptibility to Benzo(a)pyrene] which results in increased expression of CDKN1A protein]; TP53 protein promotes the reaction [Etoposide promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 protein]]; TP53 protein promotes the reaction [Etoposide results in decreased expression of IKBKB protein]; TP53 protein promotes the reaction [Etoposide results in increased expression of CDKN1A protein]; TP53 protein promotes the reaction [Etoposide results in increased expression of CYP1A1 protein]; TP53 protein promotes the reaction [Etoposide results in increased expression of ETS1 protein]; trichostatin A promotes the reaction [Etoposide results in increased expression of and results in increased acetylation of TP53 protein]; UF010 compound promotes the reaction [Etoposide results in increased expression of and results in increased acetylation of TP53 protein]
[Etoposide results in increased expression of TP53 protein] which results in increased expression of GDF15 protein; Etoposide results in increased expression of TP53 protein
cordycepin promotes the reaction [Etoposide results in increased expression of TP53 protein]; Etoposide promotes the reaction [Acetaminophen results in increased phosphorylation of TP53 protein]; Etoposide results in increased expression of and results in increased phosphorylation of TP53 protein; Niacin deficiency inhibits the reaction [Etoposide results in increased expression of TP53 protein]; Tetrachlorodibenzodioxin inhibits the reaction [Etoposide results in increased expression of and results in increased phosphorylation of TP53 protein]
TP53 protein results in increased susceptibility to Etoposide; TP53 results in increased susceptibility to Etoposide		 CTD PMID:9815696 PMID:11895857 PMID:12082016 PMID:15131059 PMID:15459018 More... NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,546 		JBrowse link
G TP53BP1 tumor protein p53 binding protein 1 increases expression
multiple interactions		 EXP Etoposide results in increased expression of TP53BP1 protein
pifithrin inhibits the reaction [Etoposide results in increased expression of and affects the localization of TP53BP1 protein]		 CTD PMID:26259609 PMID:27358234 NCBI chr15:43,403,061...43,510,640
Ensembl chr15:43,403,061...43,510,728 		JBrowse link
G TP53I3 tumor protein p53 inducible protein 3 increases expression EXP Etoposide results in increased expression of TP53I3 mRNA CTD PMID:17374387 NCBI chr 2:24,077,433...24,084,834
Ensembl chr 2:24,077,433...24,085,861 		JBrowse link
G TP53TG1 TP53 target 1 increases expression EXP Etoposide results in increased expression of TP53TG1 mRNA CTD PMID:17374387 NCBI chr 7:87,325,347...87,345,492
Ensembl chr 7:87,322,943...87,345,560 		JBrowse link
G TP73 tumor protein p73 multiple interactions
increases expression		 EXP [[Etoposide results in increased expression of TP73 protein] which results in increased expression of VDR protein] which results in increased susceptibility to Calcitriol; TP73 mutant form inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; TP73 mutant form inhibits the reaction [Etoposide results in increased activity of CASP7 protein]; TP73 mutant form inhibits the reaction [Etoposide results in increased cleavage of CASP3 protein]; TP73 mutant form inhibits the reaction [Etoposide results in increased cleavage of CASP8 protein]; TP73 protein affects the reaction [Etoposide results in increased expression of VDR mRNA]
Etoposide results in increased expression of TP73 mRNA; Etoposide results in increased expression of TP73 protein		 CTD PMID:17716971 PMID:21801448 NCBI chr 1:3,652,516...3,736,201
Ensembl chr 1:3,652,516...3,736,201 		JBrowse link
G TPI1 triosephosphate isomerase 1 multiple interactions
increases phosphorylation		 EXP CDK2 affects the reaction [Etoposide results in increased phosphorylation of TPI1 protein] CTD PMID:20149834 NCBI chr12:6,867,420...6,870,948
Ensembl chr12:6,867,119...6,870,948 		JBrowse link
G TPP2 tripeptidyl peptidase 2 multiple interactions
affects localization		 EXP
ISO		 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Etoposide affects the localization of TPP2 protein]; SB 203580 inhibits the reaction [Etoposide affects the localization of TPP2 protein]; U 0126 inhibits the reaction [Etoposide affects the localization of TPP2 protein]
4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Etoposide affects the localization of TPP2 protein]; Sirolimus promotes the reaction [Etoposide affects the localization of TPP2 protein]; U 0126 inhibits the reaction [Etoposide affects the localization of TPP2 protein]; wortmannin promotes the reaction [Etoposide affects the localization of TPP2 protein]		 CTD PMID:20643100 NCBI chr13:102,596,986...102,679,958
Ensembl chr13:102,596,958...102,679,958 		JBrowse link
G TPT1 tumor protein, translationally-controlled 1 increases expression
multiple interactions		 EXP
ISO		 Etoposide results in increased expression of TPT1 mRNA
TRP53 affects the reaction [Etoposide results in increased expression of TPT1 mRNA]; TRP53 affects the reaction [Etoposide results in increased expression of TPT1 protein]
Etoposide results in increased expression of TPT1 mRNA; Etoposide results in increased expression of TPT1 protein
TP53 affects the reaction [Etoposide results in increased expression of TPT1 mRNA]		 CTD PMID:24067374 NCBI chr13:45,333,471...45,341,183
Ensembl chr13:45,333,471...45,341,284 		JBrowse link
G TRAF2 TNF receptor associated factor 2 affects response to substance ISO TRAF2 protein affects the susceptibility to Etoposide CTD PMID:20159942 NCBI chr 9:136,881,958...136,926,607
Ensembl chr 9:136,881,912...136,926,607 		JBrowse link
G TRIB2 tribbles pseudokinase 2 affects response to substance EXP TRIB2 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 2:12,716,936...12,742,734
Ensembl chr 2:12,716,910...12,742,734 		JBrowse link
G TRIB3 tribbles pseudokinase 3 decreases expression ISO Etoposide results in decreased expression of TRIB3 mRNA CTD PMID:25270620 NCBI chr20:380,760...397,559
Ensembl chr20:362,835...397,559 		JBrowse link
G TRIM2 tripartite motif containing 2 affects response to substance
decreases expression		 EXP
ISO		 TRIM2 protein affects the susceptibility to Etoposide
Etoposide results in decreased expression of TRIM2 mRNA		 CTD PMID:16217747 PMID:25270620 NCBI chr 4:153,152,163...153,339,317
Ensembl chr 4:153,152,163...153,339,319 		JBrowse link
G TRIM38 tripartite motif containing 38 decreases expression EXP Etoposide results in decreased expression of TRIM38 mRNA CTD PMID:24211769 NCBI chr 6:25,962,802...25,991,231
Ensembl chr 6:25,962,802...25,991,231 		JBrowse link
G TRPV1 transient receptor potential cation channel subfamily V member 1 increases expression EXP Etoposide results in increased expression of TRPV1 mRNA CTD PMID:29397400 NCBI chr17:3,565,446...3,609,411
Ensembl chr17:3,565,444...3,609,411 		JBrowse link
G TTK TTK protein kinase decreases expression EXP Etoposide results in decreased expression of TTK mRNA CTD PMID:16120219 NCBI chr 6:80,004,649...80,042,527
Ensembl chr 6:80,003,887...80,042,527 		JBrowse link
G TUBA4A tubulin alpha 4a increases expression EXP Etoposide results in increased expression of TUBA4A mRNA CTD PMID:21527772 NCBI chr 2:219,249,710...219,254,740
Ensembl chr 2:219,249,710...219,277,902 		JBrowse link
G TXN2 thioredoxin 2 decreases response to substance EXP TXN2 protein results in decreased susceptibility to Etoposide CTD PMID:12080052 NCBI chr22:36,467,046...36,481,640
Ensembl chr22:36,467,046...36,481,640 		JBrowse link
G TXNIP thioredoxin interacting protein increases expression EXP Etoposide results in increased expression of TXNIP protein CTD PMID:18270325 NCBI chr 1:145,992,435...145,996,579
Ensembl chr 1:145,992,435...145,996,579 		JBrowse link
G TXNL1 thioredoxin like 1 decreases expression ISO Etoposide results in decreased expression of TXNL1 protein CTD PMID:29733421 NCBI chr18:56,597,209...56,638,592
Ensembl chr18:56,597,209...56,651,600 		JBrowse link
G TYMS thymidylate synthetase affects response to substance EXP TYMS gene polymorphism affects the susceptibility to Etoposide CTD PMID:15713801 NCBI chr18:657,653...673,578
Ensembl chr18:657,653...673,578 		JBrowse link
G TYRP1 tyrosinase related protein 1 affects response to substance EXP TYRP1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 9:12,693,385...12,710,285
Ensembl chr 9:12,685,439...12,710,285 		JBrowse link
G UBE2C ubiquitin conjugating enzyme E2 C decreases expression
multiple interactions		 EXP Etoposide results in decreased expression of UBE2C mRNA; Etoposide results in decreased expression of UBE2C protein
[Etoposide results in increased acetylation of TP53 protein mutant form] which results in increased expression of UBE2C protein; CDKN1A protein affects the reaction [Etoposide results in decreased expression of UBE2C protein]; TP53 protein affects the reaction [Etoposide results in decreased expression of UBE2C mRNA]; TP53 protein inhibits the reaction [Etoposide results in decreased expression of UBE2C protein]		 CTD PMID:17374387 PMID:27129209 NCBI chr20:45,812,644...45,816,952
Ensembl chr20:45,812,576...45,816,957 		JBrowse link
G UBL3 ubiquitin like 3 affects response to substance EXP UBL3 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr13:29,764,371...29,850,617
Ensembl chr13:29,764,371...29,850,617 		JBrowse link
G UCP2 uncoupling protein 2 decreases expression EXP Etoposide results in decreased expression of UCP2 mRNA CTD PMID:29397400 NCBI chr11:73,974,672...73,983,202
Ensembl chr11:73,974,672...73,982,843 		JBrowse link
G UGT1A1 UDP glucuronosyltransferase family 1 member A1 affects response to substance
increases glucuronidation		 EXP UGT1A1 gene polymorphism affects the susceptibility to Etoposide
UGT1A1 protein results in increased glucuronidation of Etoposide		 CTD PMID:12969965 PMID:17151191 NCBI chr 2:233,760,270...233,773,300
Ensembl chr 2:233,760,270...233,773,300 		JBrowse link
G UGT1A3 UDP glucuronosyltransferase family 1 member A3 increases glucuronidation EXP UGT1A3 protein results in increased glucuronidation of Etoposide CTD PMID:17151191 NCBI chr 2:233,729,042...233,773,300
Ensembl chr 2:233,729,042...233,773,300 		JBrowse link
G UGT1A8 UDP glucuronosyltransferase family 1 member A8 increases glucuronidation EXP UGT1A8 protein results in increased glucuronidation of Etoposide CTD PMID:17151191 NCBI chr 2:233,617,633...233,773,300
Ensembl chr 2:233,617,633...233,773,300 		JBrowse link
G UNC5C unc-5 netrin receptor C increases response to substance EXP UNC5C results in increased susceptibility to Etoposide CTD PMID:21600761 NCBI chr 4:95,162,504...95,548,973
Ensembl chr 4:95,162,504...95,549,206 		JBrowse link
G UPP2 uridine phosphorylase 2 increases expression ISO Etoposide results in increased expression of UPP2 mRNA CTD PMID:25270620 NCBI chr 2:157,995,179...158,136,154
Ensembl chr 2:157,876,679...158,136,154 		JBrowse link
G UTP3 UTP3 small subunit processome component decreases expression EXP Etoposide results in decreased expression of UTP3 mRNA CTD PMID:24211769 NCBI chr 4:70,688,532...70,690,551
Ensembl chr 4:70,688,532...70,690,551 		JBrowse link
G VCAM1 vascular cell adhesion molecule 1 multiple interactions
decreases response to substance		 EXP [IL4 protein co-treated with VCAM1 protein] inhibits the reaction [Etoposide results in decreased folding of BAX protein]; [VCAM1 protein co-treated with IL4 protein] inhibits the reaction [Etoposide inhibits the reaction [BAX protein binds to BCL2L1 protein]]; [VCAM1 protein co-treated with IL4 protein] results in decreased susceptibility to Etoposide
VCAM1 protein results in decreased susceptibility to Etoposide		 CTD PMID:10620629 NCBI chr 1:100,719,742...100,739,045
Ensembl chr 1:100,719,742...100,739,045 		JBrowse link
G VCAN versican affects response to substance EXP VCAN protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 5:83,471,744...83,582,302
Ensembl chr 5:83,471,618...83,582,303 		JBrowse link
G VDAC1 voltage dependent anion channel 1 multiple interactions ISO Etoposide promotes the reaction [VDAC1 protein binds to VDAC1 protein] CTD PMID:20937774 NCBI chr 5:133,971,871...134,114,540
Ensembl chr 5:133,971,871...134,004,975 		JBrowse link
G VDR vitamin D receptor multiple interactions
affects response to substance
increases expression		 EXP [[Etoposide results in increased expression of TP73 protein] which results in increased expression of VDR protein] which results in increased susceptibility to Calcitriol; TP73 protein affects the reaction [Etoposide results in increased expression of VDR mRNA]
VDR gene polymorphism affects the susceptibility to Etoposide; VDR intron polymorphism affects the susceptibility to Etoposide		 CTD PMID:12969965 PMID:15713801 PMID:17716971 NCBI chr12:47,841,537...47,904,994
Ensembl chr12:47,841,537...47,943,048 		JBrowse link
G VEGFA vascular endothelial growth factor A decreases response to substance EXP VEGFA mRNA results in decreased susceptibility to Etoposide CTD PMID:18494554 NCBI chr 6:43,770,211...43,786,487
Ensembl chr 6:43,770,184...43,786,487 		JBrowse link
G VEGFC vascular endothelial growth factor C multiple interactions
decreases response to substance		 EXP EDN1 mutant form inhibits the reaction [VEGFC protein results in decreased susceptibility to Etoposide]; PTGS2 mutant form inhibits the reaction [VEGFC protein results in decreased susceptibility to Etoposide] CTD PMID:24184161 NCBI chr 4:176,683,538...176,792,922
Ensembl chr 4:176,683,538...176,792,922 		JBrowse link
G VKORC1 vitamin K epoxide reductase complex subunit 1 increases expression ISO Etoposide results in increased expression of VKORC1 mRNA CTD PMID:25270620 NCBI chr16:31,090,854...31,094,797
Ensembl chr16:31,090,842...31,095,980 		JBrowse link
G WIF1 WNT inhibitory factor 1 increases response to substance EXP WIF1 protein results in increased susceptibility to Etoposide CTD PMID:15389810 NCBI chr12:65,050,626...65,121,305
Ensembl chr12:65,050,626...65,121,305 		JBrowse link
G WIPI1 WD repeat domain, phosphoinositide interacting 1 affects response to substance EXP WIPI1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr17:68,421,281...68,457,496
Ensembl chr17:68,420,948...68,457,513 		JBrowse link
G WNT3A Wnt family member 3A increases response to substance EXP WNT3A protein results in increased susceptibility to Etoposide CTD PMID:19864107 NCBI chr 1:228,006,998...228,061,271
Ensembl chr 1:228,006,998...228,061,271 		JBrowse link
G WRN WRN RecQ like helicase increases response to substance EXP WRN gene mutant form results in increased susceptibility to Etoposide CTD PMID:10725663 NCBI chr 8:31,033,810...31,176,138
Ensembl chr 8:31,033,788...31,176,138 		JBrowse link
G XAF1 XIAP associated factor 1 increases response to substance
multiple interactions
increases expression		 EXP XAF1 protein results in increased susceptibility to Etoposide
XAF1 protein affects the reaction [Etoposide results in decreased expression of MT2A protein]; XAF1 protein affects the reaction [Etoposide results in increased cleavage of PARP1 protein]
Etoposide results in increased expression of XAF1 mRNA; Etoposide results in increased expression of XAF1 protein		 CTD PMID:15843754 PMID:17570219 PMID:28507149 NCBI chr17:6,755,447...6,775,647
Ensembl chr17:6,755,447...6,775,647 		JBrowse link
G XRCC1 X-ray repair cross complementing 1 multiple interactions
affects response to substance
increases expression		 EXP 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Etoposide results in increased expression of XRCC1 mRNA]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Etoposide results in increased expression of XRCC1 protein]; resveratrol inhibits the reaction [Etoposide results in increased expression of XRCC1 mRNA]; resveratrol inhibits the reaction [Etoposide results in increased expression of XRCC1 protein]; U 0126 inhibits the reaction [Etoposide results in increased expression of XRCC1 mRNA]; U 0126 inhibits the reaction [Etoposide results in increased expression of XRCC1 protein]
XRCC1 protein affects the susceptibility to Etoposide
Etoposide results in increased expression of XRCC1 mRNA; Etoposide results in increased expression of XRCC1 protein		 CTD PMID:26046675 NCBI chr19:43,543,311...43,575,527
Ensembl chr19:43,543,311...43,580,473 		JBrowse link
G XRCC2 X-ray repair cross complementing 2 multiple interactions
increases expression		 EXP BRCA1 protein mutant form inhibits the reaction [Etoposide results in increased expression of XRCC2 protein] CTD PMID:16417649 NCBI chr 7:152,644,776...152,676,141
Ensembl chr 7:152,644,776...152,676,193 		JBrowse link
G XRCC3 X-ray repair cross complementing 3 multiple interactions
increases expression		 EXP BRCA1 protein mutant form inhibits the reaction [Etoposide results in increased expression of XRCC3 protein] CTD PMID:16417649 NCBI chr14:103,697,617...103,715,451
Ensembl chr14:103,697,609...103,715,504 		JBrowse link
G XRCC4 X-ray repair cross complementing 4 multiple interactions
decreases response to substance
increases expression		 EXP BRCA1 protein mutant form inhibits the reaction [Etoposide results in increased expression of XRCC4 protein]
XRCC4 results in decreased susceptibility to Etoposide		 CTD PMID:16417649 PMID:21785230 NCBI chr 5:83,077,547...83,374,473
Ensembl chr 5:83,077,498...83,353,787 		JBrowse link
G XRCC5 X-ray repair cross complementing 5 affects response to substance EXP XRCC5 protein affects the susceptibility to Etoposide CTD PMID:12384553 NCBI chr 2:216,109,348...216,206,293
Ensembl chr 2:216,107,464...216,206,303 		JBrowse link
G ZBED1 zinc finger BED-type containing 1 decreases expression EXP Etoposide results in decreased expression of ZBED1 mRNA CTD PMID:24211769 NCBI chr  X:2,486,435...2,500,976
NCBI chr  Y:2,486,435...2,500,976
Ensembl chr  Y:2,486,414...2,500,976
Ensembl chr  X:2,486,414...2,500,976 		JBrowse link
G ZBTB24 zinc finger and BTB domain containing 24 decreases expression EXP Etoposide results in decreased expression of ZBTB24 mRNA CTD PMID:24211769 NCBI chr 6:109,462,594...109,483,219
Ensembl chr 6:109,460,632...109,483,239 		JBrowse link
G ZDHHC11 zinc finger DHHC-type containing 11 affects response to substance EXP ZDHHC11 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 5:795,605...860,563
Ensembl chr 5:795,605...858,973 		JBrowse link
G ZFP36L1 ZFP36 ring finger protein like 1 decreases expression EXP Etoposide results in decreased expression of ZFP36L1 mRNA CTD PMID:24211769 NCBI chr14:68,787,655...68,796,243
Ensembl chr14:68,787,660...68,796,253 		JBrowse link
G ZMAT3 zinc finger matrin-type 3 increases expression EXP Etoposide results in increased expression of ZMAT3 mRNA CTD PMID:29397400 NCBI chr 3:179,017,223...179,072,513
Ensembl chr 3:178,960,121...179,072,215 		JBrowse link
G ZNF200 zinc finger protein 200 decreases expression EXP Etoposide results in decreased expression of ZNF200 mRNA CTD PMID:24211769 NCBI chr16:3,222,325...3,235,158
Ensembl chr16:3,222,325...3,236,221 		JBrowse link
G ZNF202 zinc finger protein 202 decreases expression EXP Etoposide results in decreased expression of ZNF202 mRNA CTD PMID:24211769 NCBI chr11:123,723,914...123,741,660
Ensembl chr11:123,723,914...123,741,675 		JBrowse link
G ZNF232 zinc finger protein 232 decreases expression EXP Etoposide results in decreased expression of ZNF232 mRNA CTD PMID:24211769 NCBI chr17:5,105,734...5,123,116
Ensembl chr17:5,105,269...5,123,162 		JBrowse link
G ZNF32 zinc finger protein 32 affects response to substance EXP ZNF32 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr10:43,643,862...43,648,881
Ensembl chr10:43,643,860...43,648,881 		JBrowse link
G ZNF365 zinc finger protein 365 increases expression ISO Etoposide results in increased expression of ZFP365 mRNA CTD PMID:25270620 NCBI chr10:62,643,643...62,672,010
Ensembl chr10:62,520,448...62,672,011 		JBrowse link
G ZNF45 zinc finger protein 45 decreases expression EXP Etoposide results in decreased expression of ZNF45 mRNA CTD PMID:24211769 NCBI chr19:43,912,624...43,935,282
Ensembl chr19:43,912,624...43,935,282 		JBrowse link
G ZNF544 zinc finger protein 544 decreases expression EXP Etoposide results in decreased expression of ZNF544 mRNA CTD PMID:24211769 NCBI chr19:58,228,914...58,277,455
Ensembl chr19:58,228,594...58,277,495 		JBrowse link
G ZNF750 zinc finger protein 750 increases expression ISO Etoposide results in increased expression of ZFP750 mRNA CTD PMID:25270620 NCBI chr17:82,829,434...82,840,022
Ensembl chr17:82,829,434...82,840,022 		JBrowse link
genistein 7-O-beta-D-glucoside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACHE acetylcholinesterase (Yt blood group) increases expression
multiple interactions		 ISO genistin results in increased expression of ACHE mRNA
genistin results in increased expression of and results in increased activity of ACHE protein		 CTD PMID:27019979 NCBI chr 7:100,889,994...100,896,994
Ensembl chr 7:100,889,994...100,896,974 		JBrowse link
G ACSL3 acyl-CoA synthetase long chain family member 3 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of ACSL3 mRNA CTD PMID:27424125 NCBI chr 2:222,861,036...222,944,639
Ensembl chr 2:222,860,942...222,944,639 		JBrowse link
G ALDH1A2 aldehyde dehydrogenase 1 family member A2 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of ALDH1A2 mRNA CTD PMID:27424125 NCBI chr15:57,953,429...58,065,711
Ensembl chr15:57,953,424...58,497,866 		JBrowse link
G ANPEP alanyl aminopeptidase, membrane multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of ANPEP mRNA CTD PMID:27424125 NCBI chr15:89,784,895...89,814,852
Ensembl chr15:89,784,895...89,815,401 		JBrowse link
G ATOH8 atonal bHLH transcription factor 8 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of ATOH8 mRNA CTD PMID:27424125 NCBI chr 2:85,753,991...85,791,383
Ensembl chr 2:85,751,344...85,791,383 		JBrowse link
G BCKDK branched chain keto acid dehydrogenase kinase multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of BCKDK mRNA CTD PMID:27424125 NCBI chr16:31,108,386...31,117,640
Ensembl chr16:31,106,107...31,112,791 		JBrowse link
G BPGM bisphosphoglycerate mutase multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of BPGM mRNA CTD PMID:27424125 NCBI chr 7:134,646,853...134,679,816
Ensembl chr 7:134,646,811...134,679,816 		JBrowse link
G CABP5 calcium binding protein 5 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of CABP5 mRNA CTD PMID:27424125 NCBI chr19:48,029,383...48,044,079
Ensembl chr19:48,029,383...48,044,079 		JBrowse link
G CACYBP calcyclin binding protein multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of CACYBP mRNA CTD PMID:27424125 NCBI chr 1:174,999,435...175,012,027
Ensembl chr 1:174,999,163...175,012,027 		JBrowse link
G CASP8AP2 caspase 8 associated protein 2 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of CASP8AP2 mRNA CTD PMID:27424125 NCBI chr 6:89,829,880...89,874,436
Ensembl chr 6:89,829,894...89,874,436 		JBrowse link
G CD200R1 CD200 receptor 1 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of CD200R1 mRNA CTD PMID:27424125 NCBI chr 3:112,921,205...112,975,103
Ensembl chr 3:112,921,205...112,975,103 		JBrowse link
G CEBPB CCAAT enhancer binding protein beta multiple interactions ISO genistin inhibits the reaction [Lipopolysaccharides results in increased activity of CEBPB protein] CTD PMID:15832817 NCBI chr20:50,190,583...50,192,690
Ensembl chr20:50,190,830...50,192,668 		JBrowse link
G CFAP251 cilia and flagella associated protein 251 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of CFAP251 mRNA CTD PMID:27424125 NCBI chr12:121,918,592...122,003,919
Ensembl chr12:121,918,592...122,003,927 		JBrowse link
G CYBRD1 cytochrome b reductase 1 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of CYBRD1 mRNA CTD PMID:27424125 NCBI chr 2:171,522,233...171,558,129
Ensembl chr 2:171,522,247...171,558,129 		JBrowse link
G CYP11A1 cytochrome P450 family 11 subfamily A member 1 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of CYP11A1 mRNA CTD PMID:28964809 NCBI chr15:74,337,762...74,367,646
Ensembl chr15:74,337,759...74,367,646 		JBrowse link
G DENND2D DENN domain containing 2D multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of DENND2D mRNA CTD PMID:27424125 NCBI chr 1:111,185,969...111,204,578
Ensembl chr 1:111,185,969...111,204,535 		JBrowse link
G DNMT1 DNA methyltransferase 1 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in increased expression of DNMT1 mRNA CTD PMID:28964809 NCBI chr19:10,133,346...10,194,953
Ensembl chr19:10,133,342...10,231,286 		JBrowse link
G DNMT3A DNA methyltransferase 3 alpha multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in increased expression of DNMT3A mRNA CTD PMID:28964809 NCBI chr 2:25,227,874...25,342,590
Ensembl chr 2:25,227,855...25,342,590 		JBrowse link
G DPP9 dipeptidyl peptidase 9 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of DPP9 mRNA CTD PMID:27424125 NCBI chr19:4,675,227...4,723,842
Ensembl chr19:4,674,341...4,724,673 		JBrowse link
G EDRF1 erythroid differentiation regulatory factor 1 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of EDRF1 mRNA CTD PMID:27424125 NCBI chr10:125,719,709...125,764,139
Ensembl chr10:125,719,515...125,764,143 		JBrowse link
G EFHD1 EF-hand domain family member D1 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of EFHD1 mRNA CTD PMID:27424125 NCBI chr 2:232,606,057...232,682,776
Ensembl chr 2:232,606,057...232,682,776 		JBrowse link
G ESR2 estrogen receptor 2 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in increased expression of ESR2 mRNA CTD PMID:28964809 NCBI chr14:64,226,707...64,338,613
Ensembl chr14:64,084,232...64,338,112 		JBrowse link
G FAM171A2 family with sequence similarity 171 member A2 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of FAM171A2 mRNA CTD PMID:27424125 NCBI chr17:44,353,215...44,363,853
Ensembl chr17:44,353,215...44,363,853 		JBrowse link
G FAM180A family with sequence similarity 180 member A multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of FAM180A mRNA CTD PMID:27424125 NCBI chr 7:135,729,592...135,748,813
Ensembl chr 7:135,728,348...135,748,813 		JBrowse link
G FAM210B family with sequence similarity 210 member B multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of FAM210B mRNA CTD PMID:27424125 NCBI chr20:56,358,974...56,368,663
Ensembl chr20:56,358,974...56,368,663 		JBrowse link
G FAM241B family with sequence similarity 241 member B multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of FAM241B mRNA CTD PMID:27424125 NCBI chr10:69,630,247...69,633,596
Ensembl chr10:69,630,247...69,633,596 		JBrowse link
G FGD6 FYVE, RhoGEF and PH domain containing 6 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of FGD6 mRNA CTD PMID:27424125 NCBI chr12:95,076,749...95,217,467
Ensembl chr12:95,076,749...95,217,482 		JBrowse link
G FHL2 four and a half LIM domains 2 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of FHL2 mRNA CTD PMID:27424125 NCBI chr 2:105,357,712...105,438,529
Ensembl chr 2:105,357,712...105,438,513 		JBrowse link
G G6PD glucose-6-phosphate dehydrogenase increases expression EXP genistin analog results in increased expression of G6PD mRNA CTD PMID:16719502 NCBI chr  X:154,531,390...154,547,569
Ensembl chr  X:154,517,825...154,547,572 		JBrowse link
G GALNT15 polypeptide N-acetylgalactosaminyltransferase 15 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of GALNT15 mRNA CTD PMID:27424125 NCBI chr 3:16,174,680...16,248,224
Ensembl chr 3:16,174,680...16,231,992 		JBrowse link
G GNG5 G protein subunit gamma 5 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of GNG5 mRNA CTD PMID:27424125 NCBI chr 1:84,498,325...84,506,581
Ensembl chr 1:84,498,323...84,506,581 		JBrowse link
G HIPK4 homeodomain interacting protein kinase 4 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of HIPK4 mRNA CTD PMID:27424125 NCBI chr19:40,379,271...40,390,181
Ensembl chr19:40,379,271...40,390,181 		JBrowse link
G HMCN1 hemicentin 1 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of HMCN1 mRNA CTD PMID:27424125 NCBI chr 1:185,734,391...186,190,949
Ensembl chr 1:185,734,391...186,190,949 		JBrowse link
G HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of HSD3B1 mRNA CTD PMID:28964809 NCBI chr 1:119,507,203...119,515,058
Ensembl chr 1:119,507,198...119,515,054 		JBrowse link
G IL6R interleukin 6 receptor multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of IL6R mRNA CTD PMID:27424125 NCBI chr 1:154,405,343...154,469,450
Ensembl chr 1:154,405,193...154,469,450 		JBrowse link
G ISG20L2 interferon stimulated exonuclease gene 20 like 2 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of ISG20L2 mRNA CTD PMID:27424125 NCBI chr 1:156,721,891...156,728,766
Ensembl chr 1:156,721,891...156,728,766 		JBrowse link
G KDM5A lysine demethylase 5A multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of KDM5A mRNA CTD PMID:27424125 NCBI chr12:280,057...389,320
Ensembl chr12:280,057...389,320 		JBrowse link
G KITLG KIT ligand multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of KITLG mRNA CTD PMID:27424125 NCBI chr12:88,492,793...88,580,471
Ensembl chr12:88,492,793...88,580,851 		JBrowse link
G KNSTRN kinetochore localized astrin (SPAG5) binding protein multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of KNSTRN mRNA CTD PMID:27424125 NCBI chr15:40,382,721...40,394,288
Ensembl chr15:40,382,721...40,394,288 		JBrowse link
G LDLRAP1 low density lipoprotein receptor adaptor protein 1 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of LDLRAP1 mRNA CTD PMID:27424125 NCBI chr 1:25,543,606...25,590,400
Ensembl chr 1:25,543,606...25,568,886 		JBrowse link
G LMOD1 leiomodin 1 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of LMOD1 mRNA CTD PMID:27424125 NCBI chr 1:201,896,456...201,946,548
Ensembl chr 1:201,896,456...201,946,548 		JBrowse link
G LRG1 leucine rich alpha-2-glycoprotein 1 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of LRG1 mRNA CTD PMID:27424125 NCBI chr19:4,536,402...4,540,036
Ensembl chr19:4,536,402...4,540,036 		JBrowse link
G LSR lipolysis stimulated lipoprotein receptor multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of LSR mRNA CTD PMID:27424125 NCBI chr19:35,249,002...35,267,964
Ensembl chr19:35,248,330...35,267,964 		JBrowse link
G LTF lactotransferrin increases expression ISO genistin results in increased expression of LTF mRNA CTD PMID:20049207 NCBI chr 3:46,435,645...46,485,234
Ensembl chr 3:46,435,645...46,485,234 		JBrowse link
G MRPL33 mitochondrial ribosomal protein L33 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of MRPL33 mRNA CTD PMID:27424125 NCBI chr 2:27,771,719...27,779,733
Ensembl chr 2:27,771,717...27,988,087 		JBrowse link
G MT1A metallothionein 1A increases expression EXP genistin analog results in increased expression of MT1A mRNA CTD PMID:16719502 NCBI chr16:56,638,666...56,640,087
Ensembl chr16:56,638,666...56,640,087 		JBrowse link
G MT1E metallothionein 1E increases expression EXP genistin analog results in increased expression of MT1E mRNA CTD PMID:16719502 NCBI chr16:56,625,781...56,627,112
Ensembl chr16:56,625,475...56,627,112 		JBrowse link
G MT1X metallothionein 1X increases expression EXP genistin analog results in increased expression of MT1X mRNA CTD PMID:16719502 NCBI chr16:56,682,470...56,684,196
Ensembl chr16:56,682,470...56,684,196 		JBrowse link
G MT2A metallothionein 2A increases expression EXP genistin analog results in increased expression of MT2A mRNA CTD PMID:16719502 NCBI chr16:56,608,584...56,609,497
Ensembl chr16:56,608,584...56,609,497 		JBrowse link
G MTMR11 myotubularin related protein 11 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of MTMR11 mRNA CTD PMID:27424125 NCBI chr 1:149,928,651...149,936,879
Ensembl chr 1:149,928,651...149,936,879 		JBrowse link
G MYOF myoferlin multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of MYOF mRNA CTD PMID:27424125 NCBI chr10:93,306,429...93,482,334
Ensembl chr10:93,306,429...93,482,334 		JBrowse link
G NOS2 nitric oxide synthase 2 multiple interactions ISO genistin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein] CTD PMID:15832817 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529 		JBrowse link
G NR4A1 nuclear receptor subfamily 4 group A member 1 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of NR4A1 mRNA CTD PMID:27424125 NCBI chr12:52,022,832...52,059,503
Ensembl chr12:52,022,832...52,059,507 		JBrowse link
G NR5A1 nuclear receptor subfamily 5 group A member 1 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of NR5A1 mRNA; [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of NR5A1 protein; [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in increased methylation of NR5A1 promoter; decitabine inhibits the reaction [[Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of NR5A1 mRNA] CTD PMID:28964809 NCBI chr 9:124,481,236...124,507,399
Ensembl chr 9:124,481,236...124,507,420 		JBrowse link
G PRIMA1 proline rich membrane anchor 1 increases expression ISO genistin results in increased expression of PRIMA1 mRNA CTD PMID:27019979 NCBI chr14:93,718,298...93,788,994
Ensembl chr14:93,718,298...93,788,485 		JBrowse link
G PRKACA protein kinase cAMP-activated catalytic subunit alpha multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of PRKACA mRNA CTD PMID:27424125 NCBI chr19:14,091,688...14,117,762
Ensembl chr19:14,091,688...14,118,084 		JBrowse link
G PRPF40A pre-mRNA processing factor 40 homolog A multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of PRPF40A mRNA CTD PMID:27424125 NCBI chr 2:152,651,732...152,718,019
Ensembl chr 2:152,651,593...152,718,012 		JBrowse link
G PSPC1 paraspeckle component 1 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of PSPC1 mRNA CTD PMID:27424125 NCBI chr13:19,671,205...19,782,945
Ensembl chr13:19,674,752...19,783,019 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO genistin inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA] CTD PMID:21341175 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922 		JBrowse link
G PTH1R parathyroid hormone 1 receptor multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of PTH1R mRNA CTD PMID:27424125 NCBI chr 3:46,877,721...46,903,799
Ensembl chr 3:46,877,721...46,903,799 		JBrowse link
G RASSF5 Ras association domain family member 5 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of RASSF5 mRNA CTD PMID:27424125 NCBI chr 1:206,507,531...206,589,448
Ensembl chr 1:206,507,531...206,589,448 		JBrowse link
G RGS22 regulator of G protein signaling 22 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of RGS22 mRNA CTD PMID:27424125 NCBI chr 8:99,960,936...100,106,049
Ensembl chr 8:99,960,936...100,131,268 		JBrowse link
G S1PR3 sphingosine-1-phosphate receptor 3 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of S1PR3 mRNA CTD PMID:27424125 NCBI chr 9:88,990,863...89,005,155
Ensembl chr 9:88,990,863...89,005,155 		JBrowse link
G SELPLG selectin P ligand multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of SELPLG mRNA CTD PMID:27424125 NCBI chr12:108,621,895...108,633,894
Ensembl chr12:108,621,895...108,633,894 		JBrowse link
G SIGLEC10 sialic acid binding Ig like lectin 10 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of SIGLEC10 mRNA CTD PMID:27424125 NCBI chr19:51,410,020...51,417,642
Ensembl chr19:51,410,020...51,417,803 		JBrowse link
G SLC16A1 solute carrier family 16 member 1 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of SLC16A1 mRNA CTD PMID:27424125 NCBI chr 1:112,911,847...112,956,196
Ensembl chr 1:112,911,847...112,957,593 		JBrowse link
G SLC30A1 solute carrier family 30 member 1 increases expression EXP genistin analog results in increased expression of SLC30A1 mRNA CTD PMID:16719502 NCBI chr 1:211,571,568...211,579,161
Ensembl chr 1:211,571,568...211,579,161 		JBrowse link
G SNX30 sorting nexin family member 30 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of SNX30 mRNA CTD PMID:27424125 NCBI chr 9:112,749,723...112,885,769
Ensembl chr 9:112,750,760...112,881,671 		JBrowse link
G SSC5D scavenger receptor cysteine rich family member with 5 domains multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of SSC5D mRNA CTD PMID:27424125 NCBI chr19:55,488,436...55,519,099
Ensembl chr19:55,488,404...55,519,099 		JBrowse link
G STAR steroidogenic acute regulatory protein multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of STAR mRNA; [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of STAR protein CTD PMID:28964809 NCBI chr 8:38,142,700...38,150,952
Ensembl chr 8:38,142,700...38,150,992 		JBrowse link
G STYXL1 serine/threonine/tyrosine interacting like 1 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of STYXL1 mRNA CTD PMID:27424125 NCBI chr 7:75,996,337...76,048,000
Ensembl chr 7:75,996,338...76,048,004 		JBrowse link
G SUMO1 small ubiquitin like modifier 1 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of SUMO1 mRNA CTD PMID:27424125 NCBI chr 2:202,206,171...202,238,597
Ensembl chr 2:202,206,182...202,238,599 		JBrowse link
G TC2N tandem C2 domains, nuclear multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of TC2N mRNA CTD PMID:27424125 NCBI chr14:91,779,746...91,867,536
Ensembl chr14:91,779,746...91,867,536 		JBrowse link
G TP53I11 tumor protein p53 inducible protein 11 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of TP53I11 mRNA CTD PMID:27424125 NCBI chr11:44,932,348...44,951,306
Ensembl chr11:44,885,903...44,951,306 		JBrowse link
G VCPIP1 valosin containing protein interacting protein 1 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of VCPIP1 mRNA CTD PMID:27424125 NCBI chr 8:66,628,487...66,667,231
Ensembl chr 8:66,628,487...66,667,231 		JBrowse link
ginsenoside C-K term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CXCL8 C-X-C motif chemokine ligand 8 multiple interactions EXP ginsenoside M1 inhibits the reaction [TNF protein results in increased secretion of CXCL8 protein] CTD PMID:21875580 NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716 		JBrowse link
G CXCR1 C-X-C motif chemokine receptor 1 multiple interactions EXP ginsenoside M1 inhibits the reaction [TNF protein results in increased expression of CXCR1 protein] CTD PMID:21875580 NCBI chr 2:218,162,841...218,166,962
Ensembl chr 2:218,162,841...218,166,962 		JBrowse link
G ICAM1 intercellular adhesion molecule 1 multiple interactions EXP ginsenoside M1 inhibits the reaction [TNF protein results in increased expression of ICAM1 protein] CTD PMID:21875580 NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615 		JBrowse link
G IFNG interferon gamma decreases expression ISO ginsenoside M1 results in decreased expression of IFNG mRNA CTD PMID:15914323 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740 		JBrowse link
G IL1B interleukin 1 beta decreases expression ISO ginsenoside M1 results in decreased expression of IL1B mRNA CTD PMID:15914323 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL4 interleukin 4 decreases expression ISO ginsenoside M1 results in decreased expression of IL4 mRNA CTD PMID:15914323 NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678 		JBrowse link
G IL6 interleukin 6 multiple interactions EXP ginsenoside M1 inhibits the reaction [Galactose results in increased secretion of IL6 protein] CTD PMID:29412148 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G ITGA4 integrin subunit alpha 4 multiple interactions EXP ginsenoside M1 inhibits the reaction [TNF protein results in increased expression of [ITGA4 protein binds to ITGB1 protein]] CTD PMID:21875580 NCBI chr 2:181,457,205...181,538,940
Ensembl chr 2:181,457,202...181,538,940 		JBrowse link
G ITGAL integrin subunit alpha L multiple interactions EXP ginsenoside M1 inhibits the reaction [TNF protein results in increased expression of [ITGAL protein binds to ITGB2 protein]] CTD PMID:21875580 NCBI chr16:30,472,742...30,523,185
Ensembl chr16:30,472,658...30,523,567 		JBrowse link
G ITGB1 integrin subunit beta 1 multiple interactions EXP ginsenoside M1 inhibits the reaction [TNF protein results in increased expression of [ITGA4 protein binds to ITGB1 protein]] CTD PMID:21875580 NCBI chr10:32,900,318...32,958,230
Ensembl chr10:32,887,273...33,005,792 		JBrowse link
G ITGB2 integrin subunit beta 2 multiple interactions EXP ginsenoside M1 inhibits the reaction [TNF protein results in increased expression of [ITGAL protein binds to ITGB2 protein]] CTD PMID:21875580 NCBI chr21:44,885,953...44,928,815
Ensembl chr21:44,885,953...44,931,989 		JBrowse link
G MMP9 matrix metallopeptidase 9 decreases secretion EXP ginsenoside M1 results in decreased secretion of MMP9 protein CTD PMID:21875580 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561 		JBrowse link
G NFKB1 nuclear factor kappa B subunit 1 multiple interactions ISO ginsenoside M1 results in decreased activity of [NFKB1 protein binds to RELA protein] CTD PMID:15802804 NCBI chr 4:102,501,359...102,617,302
Ensembl chr 4:102,501,330...102,617,302 		JBrowse link
G NOS2 nitric oxide synthase 2 multiple interactions ISO ginsenoside M1 results in decreased expression of and results in decreased activity of NOS2 protein CTD PMID:15802804 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529 		JBrowse link
G P2RX4 purinergic receptor P2X 4 multiple interactions EXP [ginsenoside M1 co-treated with Adenosine Triphosphate] results in increased activity of P2RX4 protein; ginsenoside M1 promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX4 protein] CTD PMID:30545933 NCBI chr12:121,210,129...121,234,106
Ensembl chr12:121,210,065...121,234,106 		JBrowse link
G P2RX7 purinergic receptor P2X 7 decreases response to substance ISO P2RX7 gene mutant form results in decreased susceptibility to ginsenoside M1 CTD PMID:30545933 NCBI chr12:121,132,876...121,188,032
Ensembl chr12:121,132,819...121,188,032 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 decreases expression ISO ginsenoside M1 results in decreased expression of PTGS2 mRNA
ginsenoside M1 results in decreased expression of PTGS2 protein		 CTD PMID:15802804 PMID:15914323 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit multiple interactions ISO ginsenoside M1 results in decreased activity of [NFKB1 protein binds to RELA protein] CTD PMID:15802804 NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090 		JBrowse link
G SELE selectin E multiple interactions EXP ginsenoside M1 inhibits the reaction [TNF protein results in increased expression of SELE protein] CTD PMID:21875580 NCBI chr 1:169,722,640...169,734,079
Ensembl chr 1:169,722,640...169,764,705 		JBrowse link
G TNF tumor necrosis factor multiple interactions
decreases expression
decreases response to substance		 EXP
ISO		 ginsenoside M1 inhibits the reaction [TNF protein results in increased expression of [ITGA4 protein binds to ITGB1 protein]]; ginsenoside M1 inhibits the reaction [TNF protein results in increased expression of [ITGAL protein binds to ITGB2 protein]]; ginsenoside M1 inhibits the reaction [TNF protein results in increased expression of CXCR1 protein]; ginsenoside M1 inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]; ginsenoside M1 inhibits the reaction [TNF protein results in increased expression of SELE protein]; ginsenoside M1 inhibits the reaction [TNF protein results in increased expression of VCAM1 protein]; ginsenoside M1 inhibits the reaction [TNF protein results in increased secretion of CXCL8 protein]
ginsenoside M1 results in decreased expression of TNF mRNA
ginsenoside M1 results in decreased susceptibility to TNF protein		 CTD PMID:15914323 PMID:21875580 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G VCAM1 vascular cell adhesion molecule 1 multiple interactions EXP ginsenoside M1 inhibits the reaction [TNF protein results in increased expression of VCAM1 protein] CTD PMID:21875580 NCBI chr 1:100,719,742...100,739,045
Ensembl chr 1:100,719,742...100,739,045 		JBrowse link
ginsenoside F1 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CXCL8 C-X-C motif chemokine ligand 8 multiple interactions EXP ginsenoside F1 inhibits the reaction [Galactose results in increased expression of CXCL8 mRNA]; ginsenoside F1 inhibits the reaction [Galactose results in increased secretion of CXCL8 protein] CTD PMID:29412148 NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716 		JBrowse link
G IL6 interleukin 6 multiple interactions EXP ginsenoside F1 inhibits the reaction [Galactose results in increased secretion of IL6 protein] CTD PMID:29412148 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit multiple interactions EXP ginsenoside F1 inhibits the reaction [Galactose affects the localization of RELA protein] CTD PMID:29412148 NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090 		JBrowse link
ginsenoside F2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 multiple interactions EXP ginsenoside F2 analog inhibits the reaction [ABCB1 protein results in increased transport of Digoxin] CTD PMID:24380838 NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323 		JBrowse link
ginsenoside Rb1 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKT1 AKT serine/threonine kinase 1 multiple interactions
increases phosphorylation		 EXP 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [ginsenoside Rb1 results in increased phosphorylation of AKT1 protein]; fulvestrant inhibits the reaction [ginsenoside Rb1 results in increased phosphorylation of AKT1 protein]; Pertussis Toxin inhibits the reaction [ginsenoside Rb1 results in increased phosphorylation of AKT1 protein] CTD PMID:19781563 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,759 		JBrowse link
G ATP6V1A ATPase H+ transporting V1 subunit A multiple interactions EXP ginsenoside Rb1 inhibits the reaction [alpha-Chlorohydrin results in decreased expression of ATP6V1A mRNA] CTD PMID:34812491 NCBI chr 3:113,747,035...113,812,056
Ensembl chr 3:113,746,770...113,812,056 		JBrowse link
G ATP6V1B2 ATPase H+ transporting V1 subunit B2 multiple interactions EXP ginsenoside Rb1 inhibits the reaction [alpha-Chlorohydrin results in decreased expression of ATP6V1B2 mRNA] CTD PMID:34812491 NCBI chr 8:20,197,381...20,221,696
Ensembl chr 8:20,197,381...20,226,819 		JBrowse link
G BMP2 bone morphogenetic protein 2 multiple interactions
increases expression		 ISO ginsenoside Rb1 inhibits the reaction [aluminum chloride results in decreased expression of BMP2 mRNA]
ginsenoside Rb1 results in increased expression of BMP2 mRNA		 CTD PMID:27470910 NCBI chr20:6,767,686...6,780,246
Ensembl chr20:6,767,686...6,780,246 		JBrowse link
G CASP3 caspase 3 multiple interactions EXP ginsenoside Rb1 inhibits the reaction [Oxidopamine results in increased activity of CASP3 protein] CTD PMID:19781563 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062 		JBrowse link
G CLCN7 chloride voltage-gated channel 7 multiple interactions EXP ginsenoside Rb1 inhibits the reaction [alpha-Chlorohydrin results in decreased expression of CLCN7 mRNA] CTD PMID:34812491 NCBI chr16:1,444,935...1,475,028
Ensembl chr16:1,444,934...1,475,077 		JBrowse link
G CTSB cathepsin B multiple interactions EXP ginsenoside Rb1 inhibits the reaction [alpha-Chlorohydrin results in decreased expression of CTSB mRNA] CTD PMID:34812491 NCBI chr 8:11,842,524...11,868,087
Ensembl chr 8:11,842,524...11,869,533 		JBrowse link
G CTSD cathepsin D multiple interactions EXP ginsenoside Rb1 inhibits the reaction [alpha-Chlorohydrin results in decreased expression of CTSD mRNA] CTD PMID:34812491 NCBI chr11:1,752,755...1,763,927
Ensembl chr11:1,752,752...1,764,573 		JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO ginsenoside Rb1 inhibits the reaction [TNFSF11 protein results in increased expression of FOS mRNA] CTD PMID:22386813 NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,282,230 		JBrowse link
G HMOX1 heme oxygenase 1 multiple interactions
increases expression		 EXP
ISO		 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [ginsenoside Rb1 results in increased expression of HMOX1 protein]; Cycloheximide inhibits the reaction [ginsenoside Rb1 results in increased expression of HMOX1 mRNA]; Cycloheximide inhibits the reaction [ginsenoside Rb1 results in increased expression of HMOX1 protein]; Dactinomycin inhibits the reaction [ginsenoside Rb1 results in increased expression of HMOX1 mRNA]; Dactinomycin inhibits the reaction [ginsenoside Rb1 results in increased expression of HMOX1 protein]; fulvestrant inhibits the reaction [ginsenoside Rb1 results in increased expression of HMOX1 mRNA]; fulvestrant inhibits the reaction [ginsenoside Rb1 results in increased expression of HMOX1 protein]; ginsenoside Rb1 results in increased expression of and results in increased activity of HMOX1 protein; Pertussis Toxin inhibits the reaction [ginsenoside Rb1 results in increased expression of HMOX1 mRNA]; Pertussis Toxin inhibits the reaction [ginsenoside Rb1 results in increased expression of HMOX1 protein]
[astragaloside A co-treated with ginsenoside Rg1 co-treated with ginsenoside Rb1 co-treated with notoginsenoside R1] results in increased expression of HMOX1 mRNA; [astragaloside A co-treated with ginsenoside Rg1 co-treated with ginsenoside Rb1 co-treated with notoginsenoside R1] results in increased expression of HMOX1 protein		 CTD PMID:19781563 PMID:25422538 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214 		JBrowse link
G IGF1 insulin like growth factor 1 multiple interactions
increases expression		 ISO ginsenoside Rb1 inhibits the reaction [aluminum chloride results in decreased expression of IGF1 mRNA]
ginsenoside Rb1 results in increased expression of IGF1 mRNA		 CTD PMID:27470910 NCBI chr12:102,395,874...102,481,839
Ensembl chr12:102,395,874...102,481,744 		JBrowse link
G IL6 interleukin 6 multiple interactions ISO ginsenoside Rb1 inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein] CTD PMID:17655881 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G ITGAM integrin subunit alpha M multiple interactions ISO ginsenoside Rb1 inhibits the reaction [Lipopolysaccharides results in increased expression of ITGAM protein] CTD PMID:17655881 NCBI chr16:31,259,975...31,332,877
Ensembl chr16:31,259,967...31,332,892 		JBrowse link
G ITGB2 integrin subunit beta 2 multiple interactions ISO ginsenoside Rb1 inhibits the reaction [Lipopolysaccharides results in increased expression of ITGB2 protein] CTD PMID:17655881 NCBI chr21:44,885,953...44,928,815
Ensembl chr21:44,885,953...44,931,989 		JBrowse link
G KCNE1 potassium voltage-gated channel subfamily E regulatory subunit 1 increases expression EXP ginsenoside Rb1 results in increased expression of KCNE1 CTD PMID:24615935 NCBI chr21:34,446,688...34,512,210
Ensembl chr21:34,446,688...34,512,214 		JBrowse link
G KCNH2 potassium voltage-gated channel subfamily H member 2 affects activity EXP ginsenoside Rb1 affects the activity of KCNH2 protein CTD PMID:15842772 NCBI chr 7:150,944,961...150,978,321
Ensembl chr 7:150,944,961...150,978,321 		JBrowse link
G LAMP1 lysosomal associated membrane protein 1 multiple interactions EXP ginsenoside Rb1 inhibits the reaction [alpha-Chlorohydrin results in decreased expression of LAMP1 mRNA] CTD PMID:34812491 NCBI chr13:113,297,239...113,323,672
Ensembl chr13:113,297,239...113,323,672 		JBrowse link
G MAP2 microtubule associated protein 2 increases expression ISO ginsenoside Rb1 results in increased expression of MAP2 mRNA CTD PMID:24599032 NCBI chr 2:209,424,047...209,734,112
Ensembl chr 2:209,424,047...209,734,147 		JBrowse link
G NFATC1 nuclear factor of activated T cells 1 multiple interactions ISO ginsenoside Rb1 inhibits the reaction [TNFSF11 protein results in increased expression of NFATC1 mRNA] CTD PMID:22386813 NCBI chr18:79,395,930...79,529,323
Ensembl chr18:79,395,856...79,529,325 		JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 multiple interactions
affects localization
increases expression		 EXP
ISO		 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [ginsenoside Rb1 results in increased localization of NFE2L2 protein]; [ginsenoside Rb1 co-treated with ginsenoside 20S-protopanaxatriol] results in increased expression of NFE2L2 protein; fulvestrant inhibits the reaction [ginsenoside Rb1 results in increased localization of NFE2L2 protein]; ginsenoside Rb1 results in increased activity of and results in increased localization of NFE2L2 protein; Pertussis Toxin inhibits the reaction [ginsenoside Rb1 results in increased localization of NFE2L2 protein]
ginsenoside Rb1 affects the localization of NFE2L2 protein
[astragaloside A co-treated with ginsenoside Rg1 co-treated with ginsenoside Rb1 co-treated with notoginsenoside R1] affects the localization of NFE2L2 protein
ginsenoside Rb1 results in increased expression of NFE2L2 mRNA		 CTD PMID:19781563 PMID:22780686 PMID:25422538 NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756 		JBrowse link
G P2RX4 purinergic receptor P2X 4 multiple interactions EXP ginsenoside Rb1 promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX4 protein] CTD PMID:30545933 NCBI chr12:121,210,129...121,234,106
Ensembl chr12:121,210,065...121,234,106 		JBrowse link
G PGR progesterone receptor increases expression EXP ginsenoside Rb1 results in increased expression of PGR protein CTD PMID:16204943 NCBI chr11:101,029,624...101,129,813
Ensembl chr11:101,029,624...101,129,813 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit multiple interactions ISO ginsenoside Rb1 inhibits the reaction [TNFSF11 protein affects the localization of RELA protein] CTD PMID:22386813 NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090 		JBrowse link
G RUNX2 RUNX family transcription factor 2 increases expression
multiple interactions		 ISO ginsenoside Rb1 results in increased expression of RUNX2 mRNA
ginsenoside Rb1 inhibits the reaction [aluminum chloride results in decreased expression of RUNX2 mRNA]		 CTD PMID:27470910 NCBI chr 6:45,328,330...45,551,082
Ensembl chr 6:45,328,157...45,664,349 		JBrowse link
G SLCO1B3 solute carrier organic anion transporter family member 1B3 multiple interactions EXP ginsenoside Rb1 binds to and results in decreased activity of SLCO1B3 protein CTD PMID:25297453 NCBI chr12:20,810,705...20,916,911
Ensembl chr12:20,810,702...20,916,911 		JBrowse link
G SQSTM1 sequestosome 1 multiple interactions
decreases expression		 EXP ginsenoside Rb1 inhibits the reaction [alpha-Chlorohydrin results in increased expression of SQSTM1 protein]
ginsenoside Rb1 results in decreased expression of SQSTM1 protein		 CTD PMID:34812491 NCBI chr 5:179,806,393...179,838,078
Ensembl chr 5:179,806,398...179,838,078 		JBrowse link
G TFEB transcription factor EB multiple interactions EXP [ginsenoside Rb1 co-treated with alpha-Chlorohydrin] affects the localization of TFEB protein; ginsenoside Rb1 inhibits the reaction [alpha-Chlorohydrin results in decreased expression of TFEB mRNA] CTD PMID:34812491 NCBI chr 6:41,683,978...41,736,223
Ensembl chr 6:41,683,978...41,736,259 		JBrowse link
G TGFB1 transforming growth factor beta 1 multiple interactions
increases expression		 ISO ginsenoside Rb1 inhibits the reaction [aluminum chloride results in decreased expression of TGFB1 mRNA]
ginsenoside Rb1 results in increased expression of TGFB1 mRNA		 CTD PMID:27470910 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922 		JBrowse link
G TNF tumor necrosis factor multiple interactions ISO ginsenoside Rb1 inhibits the reaction [TNFSF11 protein results in increased expression of TNF mRNA] CTD PMID:22386813 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TNFSF11 TNF superfamily member 11 multiple interactions
decreases response to substance		 ISO ginsenoside Rb1 inhibits the reaction [TNFSF11 protein affects the localization of RELA protein]; ginsenoside Rb1 inhibits the reaction [TNFSF11 protein results in increased expression of FOS mRNA]; ginsenoside Rb1 inhibits the reaction [TNFSF11 protein results in increased expression of NFATC1 mRNA]; ginsenoside Rb1 inhibits the reaction [TNFSF11 protein results in increased expression of TNF mRNA]
ginsenoside Rb1 results in decreased susceptibility to TNFSF11 protein		 CTD PMID:22386813 NCBI chr13:42,562,736...42,608,013
Ensembl chr13:42,562,736...42,608,013 		JBrowse link
ginsenoside Rb2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCC2 ATP binding cassette subfamily C member 2 increases expression ISO ginsenoside Rb2 results in increased expression of ABCC2 mRNA CTD PMID:23835644 NCBI chr10:99,782,640...99,852,594
Ensembl chr10:99,782,640...99,852,594 		JBrowse link
G LPL lipoprotein lipase increases secretion
decreases secretion		 ISO ginsenoside Rb2 results in increased secretion of LPL protein
ginsenoside Rb2 results in decreased secretion of LPL protein		 CTD PMID:8988629 NCBI chr 8:19,939,253...19,967,259
Ensembl chr 8:19,901,717...19,967,259 		JBrowse link
ginsenoside Rc term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLCO1B3 solute carrier organic anion transporter family member 1B3 multiple interactions EXP ginsenoside Rc binds to and results in decreased activity of SLCO1B3 protein CTD PMID:25297453 NCBI chr12:20,810,705...20,916,911
Ensembl chr12:20,810,702...20,916,911 		JBrowse link
ginsenoside Rd term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKT1 AKT serine/threonine kinase 1 multiple interactions ISO ginsenoside Rd results in increased phosphorylation of and results in increased activity of AKT1 protein CTD PMID:24599032 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,759 		JBrowse link
G APP amyloid beta precursor protein multiple interactions ISO ginsenoside Rd inhibits the reaction [APP protein modified form results in decreased expression of BCL2 mRNA]; ginsenoside Rd inhibits the reaction [APP protein modified form results in increased expression of BAX mRNA]; ginsenoside Rd inhibits the reaction [APP protein modified form results in increased expression of CASP3 protein modified form]; ginsenoside Rd inhibits the reaction [APP protein modified form results in increased expression of CYCS mRNA] CTD PMID:26111763 NCBI chr21:25,880,550...26,171,128
Ensembl chr21:25,880,535...26,171,128 		JBrowse link
G BAX BCL2 associated X, apoptosis regulator multiple interactions ISO ginsenoside Rd inhibits the reaction [APP protein modified form results in increased expression of BAX mRNA] CTD PMID:26111763 NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798 		JBrowse link
G BCL2 BCL2 apoptosis regulator multiple interactions ISO ginsenoside Rd inhibits the reaction [APP protein modified form results in decreased expression of BCL2 mRNA] CTD PMID:26111763 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128 		JBrowse link
G CASP3 caspase 3 multiple interactions ISO ginsenoside Rd inhibits the reaction [APP protein modified form results in increased expression of CASP3 protein modified form] CTD PMID:26111763 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062 		JBrowse link
G CAT catalase increases expression ISO ginsenoside Rd results in increased expression of CAT protein CTD PMID:9933756 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060 		JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A increases expression
multiple interactions		 ISO ginsenoside Rd results in increased expression of CDKN1A mRNA
staurosporine aglycone inhibits the reaction [ginsenoside Rd results in increased expression of CDKN1A mRNA]		 CTD PMID:24599032 NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,337 		JBrowse link
G CHAT choline O-acetyltransferase increases expression
multiple interactions		 ISO ginsenoside Rd results in increased expression of CHAT mRNA; ginsenoside Rd results in increased expression of CHAT protein
staurosporine aglycone inhibits the reaction [ginsenoside Rd results in increased expression of CHAT mRNA]; staurosporine aglycone inhibits the reaction [ginsenoside Rd results in increased expression of CHAT protein]		 CTD PMID:24599032 NCBI chr10:49,609,095...49,667,942
Ensembl chr10:49,609,095...49,667,942 		JBrowse link
G CYCS cytochrome c, somatic multiple interactions ISO ginsenoside Rd inhibits the reaction [APP protein modified form results in increased expression of CYCS mRNA] CTD PMID:26111763 NCBI chr 7:25,118,656...25,125,260
Ensembl chr 7:25,118,656...25,125,260 		JBrowse link
G LPL lipoprotein lipase decreases secretion ISO ginsenoside Rd results in decreased secretion of LPL protein CTD PMID:8988629 NCBI chr 8:19,939,253...19,967,259
Ensembl chr 8:19,901,717...19,967,259 		JBrowse link
G MAP2 microtubule associated protein 2 increases expression ISO ginsenoside Rd results in increased expression of MAP2 mRNA; ginsenoside Rd results in increased expression of MAP2 protein CTD PMID:24599032 NCBI chr 2:209,424,047...209,734,112
Ensembl chr 2:209,424,047...209,734,147 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 multiple interactions ISO ginsenoside Rd results in increased phosphorylation of and results in increased activity of MAPK1 protein CTD PMID:24599032 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 multiple interactions ISO ginsenoside Rd results in increased phosphorylation of and results in increased activity of MAPK3 protein CTD PMID:24599032 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506 		JBrowse link
G NGF nerve growth factor increases expression ISO ginsenoside Rd results in increased expression of NGF mRNA CTD PMID:24599032 NCBI chr 1:115,285,917...115,338,249
Ensembl chr 1:115,285,904...115,338,770 		JBrowse link
G NGFR nerve growth factor receptor increases expression ISO ginsenoside Rd results in increased expression of NGFR mRNA; ginsenoside Rd results in increased expression of NGFR protein CTD PMID:24599032 NCBI chr17:49,495,293...49,515,008
Ensembl chr17:49,495,293...49,515,008 		JBrowse link
G P2RX4 purinergic receptor P2X 4 multiple interactions EXP ginsenoside Rd promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX4 protein] CTD PMID:30545933 NCBI chr12:121,210,129...121,234,106
Ensembl chr12:121,210,065...121,234,106 		JBrowse link
G P2RX7 purinergic receptor P2X 7 decreases response to substance ISO P2RX7 gene mutant form results in decreased susceptibility to ginsenoside Rd CTD PMID:30545933 NCBI chr12:121,132,876...121,188,032
Ensembl chr12:121,132,819...121,188,032 		JBrowse link
G SLC18A3 solute carrier family 18 member A3 increases expression ISO ginsenoside Rd results in increased expression of SLC18A3 mRNA CTD PMID:24599032 NCBI chr10:49,610,310...49,612,720
Ensembl chr10:49,610,310...49,612,720 		JBrowse link
G SLC5A7 solute carrier family 5 member 7 increases expression ISO ginsenoside Rd results in increased expression of SLC5A7 mRNA CTD PMID:24599032 NCBI chr 2:107,986,524...108,013,994
Ensembl chr 2:107,986,523...108,013,994 		JBrowse link
G SLCO1B3 solute carrier organic anion transporter family member 1B3 multiple interactions EXP ginsenoside Rd binds to and results in decreased activity of SLCO1B3 protein CTD PMID:25297453 NCBI chr12:20,810,705...20,916,911
Ensembl chr12:20,810,702...20,916,911 		JBrowse link
ginsenoside Re term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB11 ATP binding cassette subfamily B member 11 increases transport ISO
EXP		 ABCB11 protein results in increased transport of ginsenoside Re CTD PMID:25297453 NCBI chr 2:168,915,390...169,031,324
Ensembl chr 2:168,915,498...169,031,324 		JBrowse link
G ABCC1 ATP binding cassette subfamily C member 1 (ABCC1 blood group) increases transport EXP ABCC1 protein results in increased transport of ginsenoside Re CTD PMID:25297453 NCBI chr16:15,949,143...16,143,053
Ensembl chr16:15,949,138...16,143,257 		JBrowse link
G ABCC2 ATP binding cassette subfamily C member 2 increases transport ISO
EXP		 ABCC2 protein results in increased transport of ginsenoside Re CTD PMID:25297453 NCBI chr10:99,782,640...99,852,594
Ensembl chr10:99,782,640...99,852,594 		JBrowse link
G ABCG2 ATP binding cassette subfamily G member 2 (JR blood group) increases transport ISO
EXP		 ABCG2 protein results in increased transport of ginsenoside Re CTD PMID:25297453 NCBI chr 4:88,090,264...88,231,626
Ensembl chr 4:88,090,150...88,231,628 		JBrowse link
G ADIPOQ adiponectin, C1Q and collagen domain containing increases expression
multiple interactions		 ISO ginsenoside Re results in increased expression of ADIPOQ mRNA
ginsenoside Re results in increased expression of and results in increased secretion of ADIPOQ protein		 CTD PMID:23545455 NCBI chr 3:186,842,710...186,858,463
Ensembl chr 3:186,842,704...186,858,463 		JBrowse link
G AIF1 allograft inflammatory factor 1 multiple interactions
decreases expression		 ISO 3-((3,5-bis(trifluoromethyl)phenyl)methyloxy)-2-phenylpiperidine inhibits the reaction [norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased expression of AIF1 protein]]]]; ginsenoside Re affects the reaction [GPX1 protein affects the expression of AIF1 protein]; ginsenoside Re inhibits the reaction [Methamphetamine results in increased expression of AIF1 protein]; ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased expression of AIF1 protein]]; norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased expression of AIF1 protein]]]
ginsenoside Re results in decreased expression of AIF1 protein		 CTD PMID:29467000 PMID:36682417 NCBI chr 6:31,615,234...31,617,015
Ensembl chr 6:31,615,217...31,617,021 		JBrowse link
G AKT1 AKT serine/threonine kinase 1 multiple interactions
increases phosphorylation		 ISO ginsenoside Re results in increased phosphorylation of and results in increased activity of AKT1 protein
ginsenoside Re results in increased phosphorylation of AKT1 protein		 CTD PMID:17878692 PMID:17885204 PMID:24599032 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,759 		JBrowse link
G AR androgen receptor multiple interactions EXP ginsenoside Re binds to and affects the activity of AR protein CTD PMID:16985185 NCBI chr  X:67,544,021...67,730,619
Ensembl chr  X:67,544,021...67,730,619 		JBrowse link
G BAX BCL2 associated X, apoptosis regulator decreases expression
multiple interactions		 ISO ginsenoside Re results in decreased expression of BAX mRNA; ginsenoside Re results in decreased expression of BAX protein
3-((3,5-bis(trifluoromethyl)phenyl)methyloxy)-2-phenylpiperidine inhibits the reaction [norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased expression of BAX protein]]]]; Acetylcysteine inhibits the reaction [ginsenoside Re inhibits the reaction [3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester results in increased expression of BAX protein]]; Cyclosporine inhibits the reaction [ginsenoside Re inhibits the reaction [3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester results in increased expression of BAX protein]]; ginsenoside Re inhibits the reaction [3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester results in increased expression of BAX protein]; ginsenoside Re inhibits the reaction [Methamphetamine results in increased expression of BAX protein]; ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased expression of BAX protein]]; norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased expression of BAX protein]]]		 CTD PMID:12674765 PMID:15621629 PMID:29467000 PMID:37308051 NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798 		JBrowse link
G BCL2 BCL2 apoptosis regulator increases expression
multiple interactions		 ISO ginsenoside Re results in increased expression of BCL2 mRNA; ginsenoside Re results in increased expression of BCL2 protein
3-((3,5-bis(trifluoromethyl)phenyl)methyloxy)-2-phenylpiperidine inhibits the reaction [norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in decreased expression of BCL2 protein]]]]; 3-nitropropionic acid inhibits the reaction [ginsenoside Re inhibits the reaction [3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester results in decreased expression of BCL2 protein]]; ginsenoside Re inhibits the reaction [3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester results in decreased expression of BCL2 protein]; ginsenoside Re inhibits the reaction [Methamphetamine results in decreased expression of BCL2 protein]; ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in decreased expression of BCL2 protein]]; norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in decreased expression of BCL2 protein]]]		 CTD PMID:15621629 PMID:29467000 PMID:37308051 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128 		JBrowse link
G BCL2L1 BCL2 like 1 multiple interactions ISO 3-nitropropionic acid inhibits the reaction [ginsenoside Re inhibits the reaction [3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester results in decreased expression of BCL2L1 protein]]; ginsenoside Re inhibits the reaction [3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester results in decreased expression of BCL2L1 protein] CTD PMID:37308051 NCBI chr20:31,664,452...31,723,963
Ensembl chr20:31,664,452...31,723,989 		JBrowse link
G CASP3 caspase 3 multiple interactions ISO
EXP		 3-((3,5-bis(trifluoromethyl)phenyl)methyloxy)-2-phenylpiperidine inhibits the reaction [norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased cleavage of CASP3 protein]]]]; 3-nitropropionic acid inhibits the reaction [ginsenoside Re inhibits the reaction [3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester results in increased cleavage of CASP3 protein]]; ginsenoside Re inhibits the reaction [3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester results in increased cleavage of CASP3 protein]; ginsenoside Re inhibits the reaction [Lipopolysaccharides results in increased activity of CASP3 protein]; ginsenoside Re inhibits the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased cleavage of CASP3 protein]]; ginsenoside Re results in decreased cleavage of and results in decreased activity of CASP3 protein; norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased cleavage of CASP3 protein]]] CTD PMID:15621629 PMID:23102375 PMID:25523949 PMID:29467000 PMID:37308051 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062 		JBrowse link
G CAT catalase multiple interactions ISO ginsenoside Re inhibits the reaction [Methamphetamine results in increased activity of CAT protein]; PRKCD affects the reaction [ginsenoside Re inhibits the reaction [Methamphetamine results in increased activity of CAT protein]] CTD PMID:24430743 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060 		JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A increases expression ISO ginsenoside Re results in increased expression of CDKN1A mRNA CTD PMID:24599032 NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,337 		JBrowse link
G CHAT choline O-acetyltransferase increases expression
multiple interactions		 ISO ginsenoside Re results in increased expression of CHAT mRNA; ginsenoside Re results in increased expression of CHAT protein
staurosporine aglycone inhibits the reaction [ginsenoside Re results in increased expression of CHAT mRNA]; staurosporine aglycone inhibits the reaction [ginsenoside Re results in increased expression of CHAT protein]		 CTD PMID:24599032 NCBI chr10:49,609,095...49,667,942
Ensembl chr10:49,609,095...49,667,942 		JBrowse link
G CHUK component of inhibitor of nuclear factor kappa B kinase complex multiple interactions ISO ginsenoside Re inhibits the reaction [TNF protein results in increased phosphorylation of CHUK protein] CTD PMID:17885204 NCBI chr10:100,186,319...100,229,596
Ensembl chr10:100,188,300...100,229,596 		JBrowse link
G CLDN1 claudin 1 multiple interactions ISO ginsenoside Re inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of CLDN1 protein] CTD PMID:22849695 NCBI chr 3:190,305,707...190,322,446
Ensembl chr 3:190,305,707...190,322,446 		JBrowse link
G CRP C-reactive protein increases expression ISO ginsenoside Re results in increased expression of CRP protein CTD PMID:16797897 NCBI chr 1:159,712,289...159,714,589
Ensembl chr 1:159,712,289...159,714,589 		JBrowse link
G CYBA cytochrome b-245 alpha chain multiple interactions ISO ginsenoside Re inhibits the reaction [GPX1 protein affects the reaction [Phencyclidine results in increased activity of CYBA protein]]; ginsenoside Re inhibits the reaction [Phencyclidine results in increased activity of CYBA protein] CTD PMID:29037473 NCBI chr16:88,643,289...88,651,053
Ensembl chr16:88,643,275...88,651,083 		JBrowse link
G CYP8B1 cytochrome P450 family 8 subfamily B member 1 increases expression ISO ginsenoside Re results in increased expression of CYP8B1 mRNA CTD PMID:23835644 NCBI chr 3:42,872,192...42,875,879
Ensembl chr 3:42,856,005...42,875,898 		JBrowse link
G ESR1 estrogen receptor 1 multiple interactions EXP ginsenoside Re binds to and affects the activity of ESR1 protein CTD PMID:16985185 NCBI chr 6:151,656,672...152,129,619
Ensembl chr 6:151,656,691...152,129,619 		JBrowse link
G FABP4 fatty acid binding protein 4 increases expression ISO ginsenoside Re results in increased expression of FABP4 mRNA CTD PMID:23545455 NCBI chr 8:81,478,419...81,483,233
Ensembl chr 8:81,478,419...81,483,236 		JBrowse link
G FAS Fas cell surface death receptor decreases expression
multiple interactions		 EXP
ISO		 ginsenoside Re results in decreased expression of FAS mRNA
ginsenoside Re inhibits the reaction [Dietary Fats results in increased expression of FAS mRNA]		 CTD PMID:21971952 NCBI chr10:88,964,050...89,017,059
Ensembl chr10:88,953,813...89,029,605 		JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit increases expression EXP ginsenoside Re results in increased expression of FOS mRNA CTD PMID:16204943 NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,282,230 		JBrowse link
G G6PC1 glucose-6-phosphatase catalytic subunit 1 decreases expression EXP ginsenoside Re results in decreased expression of G6PC1 mRNA CTD PMID:21971952 NCBI chr17:42,900,799...42,914,438
Ensembl chr17:42,900,797...42,914,438 		JBrowse link
G GPAM glycerol-3-phosphate acyltransferase, mitochondrial multiple interactions ISO ginsenoside Re inhibits the reaction [Dietary Fats results in increased expression of GPAM mRNA] CTD PMID:21971952 NCBI chr10:112,149,865...112,227,677
Ensembl chr10:112,149,865...112,215,377 		JBrowse link
G GPX1 glutathione peroxidase 1 multiple interactions ISO ginsenoside Re affects the reaction [GPX1 protein affects the expression of AIF1 protein]; ginsenoside Re affects the reaction [GPX1 protein affects the expression of and affects the localization of RELA protein]; ginsenoside Re affects the reaction [GPX1 protein affects the expression of PTAFR protein]; ginsenoside Re affects the reaction [GPX1 protein affects the phosphorylation of MAPK1 protein]; ginsenoside Re affects the reaction [GPX1 protein affects the phosphorylation of MAPK3 protein]; ginsenoside Re inhibits the reaction [GPX1 protein affects the reaction [Phencyclidine affects the localization of NCF1 protein]]; ginsenoside Re inhibits the reaction [GPX1 protein affects the reaction [Phencyclidine results in decreased activity of SOD2 protein]]; ginsenoside Re inhibits the reaction [GPX1 protein affects the reaction [Phencyclidine results in increased activity of CYBA protein]]; ginsenoside Re inhibits the reaction [GPX1 protein affects the reaction [Phencyclidine results in increased activity of SOD1 protein]] CTD PMID:29037473 PMID:36682417 NCBI chr 3:49,357,176...49,358,353
Ensembl chr 3:49,357,174...49,358,605 		JBrowse link
G GSK3B glycogen synthase kinase 3 beta increases phosphorylation ISO ginsenoside Re results in increased phosphorylation of GSK3B protein CTD PMID:17885204 NCBI chr 3:119,821,321...120,094,447
Ensembl chr 3:119,821,321...120,094,994 		JBrowse link
G HSPD1 heat shock protein family D (Hsp60) member 1 increases expression ISO ginsenoside Re results in increased expression of HSPD1 protein CTD PMID:23144451 NCBI chr 2:197,486,584...197,500,274
Ensembl chr 2:197,486,584...197,516,737 		JBrowse link
G IFNG interferon gamma decreases expression EXP ginsenoside Re results in decreased expression of IFNG protein CTD PMID:20230918 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740 		JBrowse link
G IKBKB inhibitor of nuclear factor kappa B kinase subunit beta multiple interactions ISO ginsenoside Re inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of IKBKB protein] CTD PMID:22849695 NCBI chr 8:42,271,302...42,332,460
Ensembl chr 8:42,271,302...42,332,460 		JBrowse link
G IL1B interleukin 1 beta multiple interactions ISO ginsenoside Re inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B protein]; ginsenoside Re inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]; ginsenoside Re metabolite inhibits the reaction [Oxazolone results in increased expression of IL1B mRNA]; ginsenoside Re metabolite inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1B mRNA] CTD PMID:16557482 PMID:22494059 PMID:22849695 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL6 interleukin 6 multiple interactions ISO ginsenoside Re inhibits the reaction [TNF protein results in increased expression of IL6 mRNA] CTD PMID:17885204 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G INS-IGF2 INS-IGF2 readthrough multiple interactions ISO ginsenoside Re inhibits the reaction [Dietary Fats inhibits the reaction [INS1 protein results in increased localization of SLC2A4 protein]] CTD PMID:22571876 NCBI chr11:2,129,117...2,161,209
Ensembl chr11:2,132,538...2,161,209 		JBrowse link
G IRAK1 interleukin 1 receptor associated kinase 1 multiple interactions ISO ginsenoside Re inhibits the reaction [Lipopolysaccharides results in increased degradation of IRAK1 protein]; ginsenoside Re inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of IRAK1 protein] CTD PMID:22849695 NCBI chr  X:154,010,507...154,019,902
Ensembl chr  X:154,010,506...154,019,902 		JBrowse link
G IRAK4 interleukin 1 receptor associated kinase 4 multiple interactions ISO ginsenoside Re inhibits the reaction [Lipopolysaccharides results in increased degradation of IRAK4 protein] CTD PMID:22849695 NCBI chr12:43,758,951...43,789,541
Ensembl chr12:43,758,944...43,798,307 		JBrowse link
G IRGM immunity related GTPase M decreases expression EXP ginsenoside Re results in decreased expression of IRGM protein CTD PMID:20230918 NCBI chr 5:150,846,521...150,902,402
Ensembl chr 5:150,846,521...150,900,736 		JBrowse link
G IRS1 insulin receptor substrate 1 multiple interactions
increases expression
increases phosphorylation		 ISO ginsenoside Re inhibits the reaction [TNF protein results in increased phosphorylation of IRS1 protein]
ginsenoside Re results in increased expression of IRS1 mRNA
ginsenoside Re results in increased phosphorylation of IRS1 protein		 CTD PMID:17885204 PMID:23545455 NCBI chr 2:226,731,312...226,799,820
Ensembl chr 2:226,731,312...226,799,820 		JBrowse link
G KCNE1 potassium voltage-gated channel subfamily E regulatory subunit 1 increases expression EXP ginsenoside Re results in increased expression of KCNE1 CTD PMID:24615935 NCBI chr21:34,446,688...34,512,210
Ensembl chr21:34,446,688...34,512,214 		JBrowse link
G LPL lipoprotein lipase increases secretion ISO ginsenoside Re results in increased secretion of LPL protein CTD PMID:8988629 NCBI chr 8:19,939,253...19,967,259
Ensembl chr 8:19,901,717...19,967,259 		JBrowse link
G LRPPRC leucine rich pentatricopeptide repeat containing increases expression ISO ginsenoside Re results in increased expression of LRPPRC protein CTD PMID:23144451 NCBI chr 2:43,886,224...43,996,265
Ensembl chr 2:43,886,224...43,996,226 		JBrowse link
G MAP2 microtubule associated protein 2 increases expression ISO ginsenoside Re results in increased expression of MAP2 mRNA; ginsenoside Re results in increased expression of MAP2 protein CTD PMID:24599032 NCBI chr 2:209,424,047...209,734,112
Ensembl chr 2:209,424,047...209,734,147 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 multiple interactions
increases phosphorylation		 ISO ginsenoside Re affects the reaction [GPX1 protein affects the phosphorylation of MAPK1 protein]; ginsenoside Re results in increased phosphorylation of and results in increased activity of MAPK1 protein
ginsenoside Re results in increased phosphorylation of MAPK1 protein		 CTD PMID:24599032 PMID:36682417 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 multiple interactions
increases phosphorylation		 ISO ginsenoside Re affects the reaction [GPX1 protein affects the phosphorylation of MAPK3 protein]; ginsenoside Re results in increased phosphorylation of and results in increased activity of MAPK3 protein
ginsenoside Re results in increased phosphorylation of MAPK3 protein		 CTD PMID:24599032 PMID:36682417 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506 		JBrowse link
G MPO myeloperoxidase multiple interactions ISO ginsenoside Re inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein] CTD PMID:22849695 NCBI chr17:58,269,855...58,280,935
Ensembl chr17:58,269,855...58,280,935 		JBrowse link
G MYL9 myosin light chain 9 affects phosphorylation ISO ginsenoside Re affects the phosphorylation of MYL9 protein CTD PMID:24658813 NCBI chr20:36,541,519...36,551,447
Ensembl chr20:36,541,497...36,551,447 		JBrowse link
G MYLK myosin light chain kinase affects expression ISO ginsenoside Re affects the expression of MYLK mRNA; ginsenoside Re affects the expression of MYLK protein CTD PMID:24658813 NCBI chr 3:123,610,049...123,884,332
Ensembl chr 3:123,610,049...123,884,332 		JBrowse link
G NCF1 neutrophil cytosolic factor 1 multiple interactions ISO ginsenoside Re inhibits the reaction [GPX1 protein affects the reaction [Phencyclidine affects the localization of NCF1 protein]]; ginsenoside Re inhibits the reaction [Phencyclidine affects the localization of NCF1 protein] CTD PMID:29037473 NCBI chr 7:74,774,011...74,789,315
Ensembl chr 7:74,774,011...74,789,315 		JBrowse link
G NFKBIA NFKB inhibitor alpha multiple interactions ISO ginsenoside Re inhibits the reaction [TNF protein results in increased degradation of NFKBIA protein] CTD PMID:17885204 NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749 		JBrowse link
G NGF nerve growth factor increases expression ISO ginsenoside Re results in increased expression of NGF mRNA CTD PMID:24599032 NCBI chr 1:115,285,917...115,338,249
Ensembl chr 1:115,285,904...115,338,770 		JBrowse link
G NGFR nerve growth factor receptor increases expression ISO ginsenoside Re results in increased expression of NGFR mRNA; ginsenoside Re results in increased expression of NGFR protein CTD PMID:24599032 NCBI chr17:49,495,293...49,515,008
Ensembl chr17:49,495,293...49,515,008 		JBrowse link
G NOS2 nitric oxide synthase 2 decreases expression
multiple interactions		 ISO ginsenoside Re results in decreased expression of NOS2 protein
ginsenoside Re inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]		 CTD PMID:15621629 PMID:23102375 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529 		JBrowse link
G NOS3 nitric oxide synthase 3 multiple interactions
increases phosphorylation		 EXP 2-aminoethoxydiphenyl borate inhibits the reaction [ginsenoside Re results in increased phosphorylation of NOS3 protein]; Calcium deficiency inhibits the reaction [ginsenoside Re results in increased phosphorylation of NOS3 protein]; Mifepristone inhibits the reaction [ginsenoside Re results in increased phosphorylation of NOS3 protein] CTD PMID:17490654 NCBI chr 7:150,991,017...151,014,588
Ensembl chr 7:150,991,017...151,014,588 		JBrowse link
G NR0B2 nuclear receptor subfamily 0 group B member 2 increases expression EXP ginsenoside Re results in increased expression of NR0B2 mRNA CTD PMID:21971952 NCBI chr 1:26,911,489...26,913,975
Ensembl chr 1:26,911,489...26,913,975 		JBrowse link
G NR3C1 nuclear receptor subfamily 3 group C member 1 multiple interactions
increases activity		 EXP [ginsenoside Re results in increased activity of NR3C1 protein] which results in increased abundance of Nitric Oxide CTD PMID:17490654 NCBI chr 5:143,277,931...143,435,512
Ensembl chr 5:143,277,931...143,435,512 		JBrowse link
G OCLN occludin multiple interactions ISO ginsenoside Re inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of OCLN protein] CTD PMID:22849695 NCBI chr 5:69,492,547...69,558,104
Ensembl chr 5:69,492,292...69,558,104 		JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 multiple interactions EXP ginsenoside Re inhibits the reaction [Methamphetamine results in increased cleavage of PARP1 protein] CTD PMID:25523949 NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154 		JBrowse link
G PCK1 phosphoenolpyruvate carboxykinase 1 multiple interactions
decreases expression		 ISO
EXP		 ginsenoside Re inhibits the reaction [Dietary Fats results in increased expression of PCK1 mRNA]
ginsenoside Re results in decreased expression of PCK1 mRNA		 CTD PMID:21971952 NCBI chr20:57,561,110...57,568,121
Ensembl chr20:57,561,080...57,568,121 		JBrowse link
G PDYN prodynorphin multiple interactions ISO 3-((3,5-bis(trifluoromethyl)phenyl)methyloxy)-2-phenylpiperidine inhibits the reaction [norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in decreased expression of BCL2 protein]]]]; 3-((3,5-bis(trifluoromethyl)phenyl)methyloxy)-2-phenylpiperidine inhibits the reaction [norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in decreased expression of TH protein]]]]; 3-((3,5-bis(trifluoromethyl)phenyl)methyloxy)-2-phenylpiperidine inhibits the reaction [norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased cleavage of CASP3 protein]]]]; 3-((3,5-bis(trifluoromethyl)phenyl)methyloxy)-2-phenylpiperidine inhibits the reaction [norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased expression of AIF1 protein]]]]; 3-((3,5-bis(trifluoromethyl)phenyl)methyloxy)-2-phenylpiperidine inhibits the reaction [norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased expression of BAX protein]]]]; ginsenoside Re inhibits the reaction [Methamphetamine results in decreased expression of PDYN mRNA]; ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in decreased expression of BCL2 protein]]; ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in decreased expression of TH protein]]; ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased cleavage of CASP3 protein]]; ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased expression of AIF1 protein]]; ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased expression of BAX protein]]; norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in decreased expression of BCL2 protein]]]; norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in decreased expression of TH protein]]]; norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased cleavage of CASP3 protein]]]; norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased expression of AIF1 protein]]]; norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased expression of BAX protein]]] CTD PMID:29467000 NCBI chr20:1,978,756...1,994,285
Ensembl chr20:1,978,757...1,994,285 		JBrowse link
G PGR progesterone receptor multiple interactions
increases expression		 EXP ginsenoside Re binds to and affects the activity of PGR protein
ginsenoside Re results in increased expression of PGR protein		 CTD PMID:16204943 PMID:16985185 NCBI chr11:101,029,624...101,129,813
Ensembl chr11:101,029,624...101,129,813 		JBrowse link
G PPARG peroxisome proliferator activated receptor gamma increases expression ISO ginsenoside Re results in increased expression of PPARG mRNA CTD PMID:23545455 NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356 		JBrowse link
G PRKAA1 protein kinase AMP-activated catalytic subunit alpha 1 increases phosphorylation
multiple interactions		 EXP
ISO		 ginsenoside Re results in increased phosphorylation of PRKAA1 protein
ginsenoside Re inhibits the reaction [Dietary Fats results in decreased phosphorylation of PRKAA1 protein]		 CTD PMID:21971952 NCBI chr 5:40,759,389...40,798,374
Ensembl chr 5:40,759,389...40,798,374 		JBrowse link
G PRKCD protein kinase C delta multiple interactions
increases response to substance		 ISO
EXP		 3-nitropropionic acid inhibits the reaction [ginsenoside Re inhibits the reaction [3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester results in increased cleavage of and results in increased phosphorylation of PRKCD protein]]; ginsenoside Re inhibits the reaction [3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester results in increased cleavage of and results in increased phosphorylation of PRKCD protein]; ginsenoside Re inhibits the reaction [Methamphetamine affects the localization of PRKCD protein]; PRKCD affects the reaction [ginsenoside Re inhibits the reaction [Methamphetamine results in increased activity of CAT protein]]; PRKCD affects the reaction [ginsenoside Re inhibits the reaction [Methamphetamine results in increased activity of SOD1 protein]]
ginsenoside Re inhibits the reaction [Methamphetamine affects the localization of PRKCD protein]; ginsenoside Re inhibits the reaction [Methamphetamine results in increased expression of and results in increased cleavage of PRKCD protein]
PRKCD results in increased susceptibility to ginsenoside Re		 CTD PMID:24430743 PMID:25523949 PMID:37308051 NCBI chr 3:53,161,209...53,192,717
Ensembl chr 3:53,156,009...53,192,717 		JBrowse link
G PTAFR platelet activating factor receptor multiple interactions
decreases expression		 ISO ginsenoside Re affects the reaction [GPX1 protein affects the expression of PTAFR protein]
ginsenoside Re results in decreased expression of PTAFR protein		 CTD PMID:36682417 NCBI chr 1:28,147,166...28,193,856
Ensembl chr 1:28,147,166...28,193,936 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO ginsenoside Re inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]; ginsenoside Re metabolite inhibits the reaction [Oxazolone results in increased expression of PTGS2 mRNA]; ginsenoside Re metabolite inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA] CTD PMID:16557482 PMID:23102375 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit multiple interactions ISO ginsenoside Re affects the reaction [GPX1 protein affects the expression of and affects the localization of RELA protein]; ginsenoside Re results in decreased expression of and affects the localization of RELA protein CTD PMID:36682417 NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090 		JBrowse link
G RPS6KB1 ribosomal protein S6 kinase B1 increases phosphorylation ISO ginsenoside Re results in increased phosphorylation of RPS6KB1 protein CTD PMID:17885204 NCBI chr17:59,893,121...59,950,574
Ensembl chr17:59,893,046...59,950,574 		JBrowse link
G SCD stearoyl-CoA desaturase decreases expression EXP ginsenoside Re results in decreased expression of SCD mRNA CTD PMID:21971952 NCBI chr10:100,347,233...100,364,826
Ensembl chr10:100,347,233...100,364,826 		JBrowse link
G SLC18A3 solute carrier family 18 member A3 increases expression ISO ginsenoside Re results in increased expression of SLC18A3 mRNA CTD PMID:24599032 NCBI chr10:49,610,310...49,612,720
Ensembl chr10:49,610,310...49,612,720 		JBrowse link
G SLC2A4 solute carrier family 2 member 4 multiple interactions
increases localization		 ISO ginsenoside Re inhibits the reaction [Dietary Fats inhibits the reaction [INS1 protein results in increased localization of SLC2A4 protein]]
ginsenoside Re results in increased localization of SLC2A4 protein		 CTD PMID:17885204 PMID:22571876 PMID:23545455 NCBI chr17:7,281,718...7,288,257
Ensembl chr17:7,281,718...7,288,257 		JBrowse link
G SLC5A7 solute carrier family 5 member 7 increases expression ISO ginsenoside Re results in increased expression of SLC5A7 mRNA CTD PMID:24599032 NCBI chr 2:107,986,524...108,013,994
Ensembl chr 2:107,986,523...108,013,994 		JBrowse link
G SLCO1B3 solute carrier organic anion transporter family member 1B3 multiple interactions EXP
ISO		 SLCO1B3 protein binds to and results in increased transport of ginsenoside Re
SLCO1B2 protein binds to and results in increased transport of ginsenoside Re		 CTD PMID:25297453 NCBI chr12:20,810,705...20,916,911
Ensembl chr12:20,810,702...20,916,911 		JBrowse link
G SOCS3 suppressor of cytokine signaling 3 multiple interactions ISO ginsenoside Re inhibits the reaction [TNF protein results in increased expression of SOCS3 mRNA] CTD PMID:17885204 NCBI chr17:78,356,778...78,360,925
Ensembl chr17:78,356,778...78,360,077 		JBrowse link
G SOD1 superoxide dismutase 1 multiple interactions
decreases activity		 ISO ginsenoside Re inhibits the reaction [GPX1 protein affects the reaction [Phencyclidine results in increased activity of SOD1 protein]]; ginsenoside Re inhibits the reaction [Methamphetamine results in increased activity of SOD1 protein]; PRKCD affects the reaction [ginsenoside Re inhibits the reaction [Methamphetamine results in increased activity of SOD1 protein]]
ginsenoside Re results in decreased activity of SOD1 protein		 CTD PMID:24430743 PMID:29037473 PMID:36682417 NCBI chr21:31,659,693...31,668,931
Ensembl chr21:31,659,666...31,668,931 		JBrowse link
G SOD2 superoxide dismutase 2 multiple interactions ISO ginsenoside Re inhibits the reaction [3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester results in decreased activity of SOD2 protein]; ginsenoside Re inhibits the reaction [GPX1 protein affects the reaction [Phencyclidine results in decreased activity of SOD2 protein]] CTD PMID:29037473 PMID:37308051 NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529 		JBrowse link
G SREBF1 sterol regulatory element binding transcription factor 1 multiple interactions
decreases expression		 ISO
EXP		 ginsenoside Re inhibits the reaction [Dietary Fats results in increased expression of SREBF1 mRNA]
ginsenoside Re results in decreased expression of SREBF1 mRNA		 CTD PMID:21971952 NCBI chr17:17,811,334...17,836,986
Ensembl chr17:17,810,399...17,837,002 		JBrowse link
G STK11 serine/threonine kinase 11 increases phosphorylation EXP ginsenoside Re results in increased phosphorylation of STK11 protein CTD PMID:21971952 NCBI chr19:1,205,778...1,228,431
Ensembl chr19:1,177,558...1,228,431 		JBrowse link
G TAC1 tachykinin precursor 1 multiple interactions ISO ginsenoside Re inhibits the reaction [Methamphetamine results in increased expression of TAC1 mRNA]; ginsenoside Re inhibits the reaction [Methamphetamine results in increased expression of TAC1 protein modified form]; norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [Methamphetamine results in increased expression of TAC1 mRNA]]; norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [Methamphetamine results in increased expression of TAC1 protein modified form]] CTD PMID:29467000 NCBI chr 7:97,732,086...97,740,472
Ensembl chr 7:97,732,084...97,740,472 		JBrowse link
G TBC1D4 TBC1 domain family member 4 increases phosphorylation ISO ginsenoside Re results in increased phosphorylation of TBC1D4 protein CTD PMID:17885204 NCBI chr13:75,283,503...75,482,169
Ensembl chr13:75,283,503...75,482,169 		JBrowse link
G TFF1 trefoil factor 1 increases expression EXP ginsenoside Re results in increased expression of TFF1 mRNA CTD PMID:16204943 NCBI chr21:42,362,282...42,366,535
Ensembl chr21:42,362,282...42,366,535 		JBrowse link
G TH tyrosine hydroxylase multiple interactions EXP
ISO		 ginsenoside Re inhibits the reaction [Methamphetamine results in decreased expression of and results in decreased activity of TH protein]
3-((3,5-bis(trifluoromethyl)phenyl)methyloxy)-2-phenylpiperidine inhibits the reaction [norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in decreased expression of TH protein]]]]; ginsenoside Re inhibits the reaction [Methamphetamine results in decreased expression of TH protein]; ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in decreased expression of TH protein]]; norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in decreased expression of TH protein]]]		 CTD PMID:25523949 PMID:29467000 NCBI chr11:2,163,929...2,171,815
Ensembl chr11:2,163,929...2,171,815 		JBrowse link
G TJP1 tight junction protein 1 multiple interactions ISO ginsenoside Re inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of TJP1 protein] CTD PMID:22849695 NCBI chr15:29,699,367...29,969,049
Ensembl chr15:29,699,367...29,968,915 		JBrowse link
G TLR4 toll like receptor 4 multiple interactions ISO ginsenoside Re inhibits the reaction [Lipopolysaccharides binds to TLR4 protein] CTD PMID:22849695 NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735 		JBrowse link
G TNF tumor necrosis factor multiple interactions ISO ginsenoside Re inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; ginsenoside Re inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]; ginsenoside Re inhibits the reaction [TNF protein results in increased degradation of NFKBIA protein]; ginsenoside Re inhibits the reaction [TNF protein results in increased expression of IL6 mRNA]; ginsenoside Re inhibits the reaction [TNF protein results in increased expression of SOCS3 mRNA]; ginsenoside Re inhibits the reaction [TNF protein results in increased phosphorylation of CHUK protein]; ginsenoside Re inhibits the reaction [TNF protein results in increased phosphorylation of IRS1 protein]; ginsenoside Re metabolite inhibits the reaction [Oxazolone results in increased expression of TNF mRNA]; ginsenoside Re metabolite inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF mRNA]; ginsenoside Re results in decreased expression of and results in decreased secretion of TNF protein CTD PMID:16557482 PMID:17885204 PMID:22494059 PMID:22849695 PMID:23545455 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
ginsenoside Rf term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOA1 apolipoprotein A1 multiple interactions
decreases expression		 ISO ginsenoside Rf inhibits the reaction [pirinixic acid results in decreased expression of APOA1 mRNA]; ginsenoside Rf inhibits the reaction [pirinixic acid results in decreased expression of APOA1 protein]; PPARA protein affects the reaction [ginsenoside Rf inhibits the reaction [pirinixic acid results in decreased expression of APOA1 mRNA]]
ginsenoside Rf results in decreased expression of APOA1 protein		 CTD PMID:16297877 NCBI chr11:116,835,751...116,837,950
Ensembl chr11:116,835,751...116,837,622 		JBrowse link
G APOC3 apolipoprotein C3 multiple interactions
decreases expression
increases expression		 ISO ginsenoside Rf inhibits the reaction [pirinixic acid results in decreased expression of APOC3 mRNA]; ginsenoside Rf inhibits the reaction [pirinixic acid results in decreased expression of APOC3 protein]; PPARA protein affects the reaction [ginsenoside Rf inhibits the reaction [pirinixic acid results in decreased expression of APOC3 mRNA]]; PPARA protein affects the reaction [ginsenoside Rf results in increased expression of APOC3 mRNA]
ginsenoside Rf results in decreased expression of APOC3 protein		 CTD PMID:16297877 NCBI chr11:116,829,907...116,833,072
Ensembl chr11:116,829,706...116,833,072 		JBrowse link
G KCNH2 potassium voltage-gated channel subfamily H member 2 affects activity EXP ginsenoside Rf affects the activity of KCNH2 protein CTD PMID:15842772 NCBI chr 7:150,944,961...150,978,321
Ensembl chr 7:150,944,961...150,978,321 		JBrowse link
G PPARA peroxisome proliferator activated receptor alpha multiple interactions
decreases expression		 ISO ginsenoside Rf binds to and results in decreased activity of PPARA protein; ginsenoside Rf inhibits the reaction [pirinixic acid results in increased activity of PPARA protein]; ginsenoside Rf inhibits the reaction [pirinixic acid results in increased expression of PPARA mRNA]; PPARA protein affects the reaction [ginsenoside Rf inhibits the reaction [pirinixic acid results in decreased expression of APOA1 mRNA]]; PPARA protein affects the reaction [ginsenoside Rf inhibits the reaction [pirinixic acid results in decreased expression of APOC3 mRNA]]; PPARA protein affects the reaction [ginsenoside Rf results in increased expression of APOC3 mRNA]
ginsenoside Rf results in decreased expression of PPARA mRNA		 CTD PMID:16297877 NCBI chr22:46,150,526...46,243,756
Ensembl chr22:46,150,521...46,243,755 		JBrowse link
ginsenoside Rg1 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB11 ATP binding cassette subfamily B member 11 increases transport
multiple interactions		 ISO
EXP		 ABCB11 protein results in increased transport of ginsenoside Rg1
ginsenoside Rg1 inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of ABCB11 mRNA]; ginsenoside Rg1 inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of ABCB11 protein]
ginsenoside Rg1 promotes the reaction [Carbon Tetrachloride results in increased expression of ABCB11 protein]		 CTD PMID:25297453 PMID:29964319 PMID:32198087 NCBI chr 2:168,915,390...169,031,324
Ensembl chr 2:168,915,498...169,031,324 		JBrowse link
G ABCC1 ATP binding cassette subfamily C member 1 (ABCC1 blood group) increases transport EXP ABCC1 protein results in increased transport of ginsenoside Rg1 CTD PMID:25297453 NCBI chr16:15,949,143...16,143,053
Ensembl chr16:15,949,138...16,143,257 		JBrowse link
G ABCC2 ATP binding cassette subfamily C member 2 increases transport
multiple interactions
increases expression		 ISO
EXP		 ABCC2 protein results in increased transport of ginsenoside Rg1
ginsenoside Rg1 inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of ABCC2 mRNA]; ginsenoside Rg1 inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of ABCC2 protein]
ginsenoside Rg1 results in increased expression of ABCC2 protein
ginsenoside Rg1 promotes the reaction [Carbon Tetrachloride results in increased expression of ABCC2 protein]; Tretinoin inhibits the reaction [ginsenoside Rg1 promotes the reaction [Carbon Tetrachloride results in increased expression of ABCC2 protein]]		 CTD PMID:25297453 PMID:29964319 PMID:32198087 NCBI chr10:99,782,640...99,852,594
Ensembl chr10:99,782,640...99,852,594 		JBrowse link
G ABCC3 ATP binding cassette subfamily C member 3 increases expression
multiple interactions		 ISO ginsenoside Rg1 results in increased expression of ABCC3 protein
ginsenoside Rg1 promotes the reaction [Carbon Tetrachloride results in increased expression of ABCC3 protein]; Tretinoin inhibits the reaction [ginsenoside Rg1 promotes the reaction [Carbon Tetrachloride results in increased expression of ABCC3 protein]]		 CTD PMID:29964319 NCBI chr17:50,634,881...50,692,253
Ensembl chr17:50,634,777...50,692,253 		JBrowse link
G ABCC4 ATP binding cassette subfamily C member 4 (PEL blood group) multiple interactions
increases expression		 ISO ginsenoside Rg1 promotes the reaction [Carbon Tetrachloride results in increased expression of ABCC4 protein]
ginsenoside Rg1 results in increased expression of ABCC4 protein		 CTD PMID:29964319 NCBI chr13:95,019,835...95,301,451
Ensembl chr13:95,019,835...95,301,475 		JBrowse link
G ABCG2 ATP binding cassette subfamily G member 2 (JR blood group) increases transport ISO
EXP		 ABCG2 protein results in increased transport of ginsenoside Rg1 CTD PMID:25297453 NCBI chr 4:88,090,264...88,231,626
Ensembl chr 4:88,090,150...88,231,628 		JBrowse link
G ACHE acetylcholinesterase (Yt blood group) decreases activity ISO ginsenoside Rg1 results in decreased activity of ACHE protein CTD PMID:20564503 NCBI chr 7:100,889,994...100,896,994
Ensembl chr 7:100,889,994...100,896,974 		JBrowse link
G ADAM10 ADAM metallopeptidase domain 10 multiple interactions ISO ginsenoside Rg1 inhibits the reaction [[APP protein alternative form co-treated with Dexamethasone] results in decreased expression of ADAM10 mRNA] CTD PMID:22484447 NCBI chr15:58,588,809...58,749,707
Ensembl chr15:58,588,809...58,749,791 		JBrowse link
G AKT1 AKT serine/threonine kinase 1 multiple interactions ISO
EXP		 ginsenoside Rg1 inhibits the reaction [Chlorpyrifos results in decreased phosphorylation of AKT1 protein]; ginsenoside Rg1 inhibits the reaction [Dibutyl Phthalate results in decreased expression of AKT1 mRNA]; ginsenoside Rg1 inhibits the reaction [Dibutyl Phthalate results in decreased phosphorylation of AKT1 protein]
ginsenoside Rg1 inhibits the reaction [Doxorubicin results in increased expression of AKT1 mRNA]
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [ginsenoside Rg1 inhibits the reaction [Lipopolysaccharides results in decreased phosphorylation of AKT1 protein]]; ginsenoside Rg1 inhibits the reaction [Lipopolysaccharides results in decreased phosphorylation of AKT1 protein]		 CTD PMID:33331133 PMID:34783124 PMID:34859534 PMID:36811218 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,759 		JBrowse link
G APAF1 apoptotic peptidase activating factor 1 multiple interactions EXP ginsenoside Rg1 promotes the reaction [Doxorubicin results in increased expression of APAF1 mRNA] CTD PMID:34783124 NCBI chr12:98,645,290...98,735,433
Ensembl chr12:98,645,149...98,735,433 		JBrowse link
G APP amyloid beta precursor protein multiple interactions ISO ginsenoside Rg1 inhibits the reaction [[APP protein alternative form co-treated with Dexamethasone] results in decreased expression of ADAM10 mRNA]; ginsenoside Rg1 inhibits the reaction [[APP protein alternative form co-treated with Dexamethasone] results in increased expression of APP mRNA]; ginsenoside Rg1 inhibits the reaction [[APP protein alternative form co-treated with Dexamethasone] results in increased expression of APP protein alternative form]; ginsenoside Rg1 inhibits the reaction [[APP protein alternative form co-treated with Dexamethasone] results in increased expression of APP protein]; ginsenoside Rg1 inhibits the reaction [[APP protein alternative form co-treated with Dexamethasone] results in increased expression of BACE1 mRNA]; ginsenoside Rg1 results in decreased susceptibility to [APP protein alternative form co-treated with Dexamethasone] CTD PMID:22484447 NCBI chr21:25,880,550...26,171,128
Ensembl chr21:25,880,535...26,171,128 		JBrowse link
G ATF6 activating transcription factor 6 multiple interactions EXP ginsenoside Rg1 inhibits the reaction [Lipopolysaccharides results in increased expression of ATF6 protein] CTD PMID:30918470 NCBI chr 1:161,766,320...161,964,070
Ensembl chr 1:161,766,298...161,977,574 		JBrowse link
G ATM ATM serine/threonine kinase multiple interactions EXP ginsenoside Rg1 promotes the reaction [Doxorubicin results in increased expression of ATM mRNA] CTD PMID:34783124 NCBI chr11:108,223,067...108,369,102
Ensembl chr11:108,222,804...108,369,102 		JBrowse link
G BACE1 beta-secretase 1 multiple interactions ISO ginsenoside Rg1 inhibits the reaction [[APP protein alternative form co-treated with Dexamethasone] results in increased expression of BACE1 mRNA] CTD PMID:22484447 NCBI chr11:117,285,698...117,316,256
Ensembl chr11:117,285,232...117,316,259 		JBrowse link
G BAD BCL2 associated agonist of cell death multiple interactions ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [ginsenoside Rg1 inhibits the reaction [Rotenone results in increased phosphorylation of BAD protein]]; ginsenoside Rg1 inhibits the reaction [Rotenone results in increased phosphorylation of BAD protein]; Mifepristone inhibits the reaction [ginsenoside Rg1 inhibits the reaction [Rotenone results in increased phosphorylation of BAD protein]]; SH-6 compound inhibits the reaction [ginsenoside Rg1 inhibits the reaction [Rotenone results in increased phosphorylation of BAD protein]] CTD PMID:17123556 NCBI chr11:64,269,828...64,284,704
Ensembl chr11:64,269,830...64,284,704 		JBrowse link
G BAX BCL2 associated X, apoptosis regulator increases expression
multiple interactions		 ISO
EXP		 ginsenoside Rg1 results in increased expression of BAX protein
ginsenoside Rg1 inhibits the reaction [Chlorpyrifos results in increased expression of BAX protein]
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [ginsenoside Rg1 inhibits the reaction [Lipopolysaccharides results in increased expression of BAX protein]]; ginsenoside Rg1 inhibits the reaction [Lipopolysaccharides results in increased expression of BAX protein]
ginsenoside Rg1 promotes the reaction [Doxorubicin results in increased expression of BAX mRNA]		 CTD PMID:28371286 PMID:34783124 PMID:34859534 PMID:36811218 NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798 		JBrowse link
G BCL2 BCL2 apoptosis regulator decreases expression
multiple interactions		 ISO ginsenoside Rg1 results in decreased expression of BCL2 protein
ginsenoside Rg1 inhibits the reaction [Chlorpyrifos results in decreased expression of BCL2 protein]
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [ginsenoside Rg1 inhibits the reaction [Lipopolysaccharides results in decreased expression of BCL2 protein]]; ginsenoside Rg1 inhibits the reaction [Lipopolysaccharides results in decreased expression of BCL2 protein]; ginsenoside Rg1 inhibits the reaction [Oxygen deficiency results in decreased expression of BCL2 protein]		 CTD PMID:26593335 PMID:28371286 PMID:34859534 PMID:36811218 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128 		JBrowse link
G CASP3 caspase 3 multiple interactions
increases activity		 EXP
ISO		 ginsenoside Rg1 inhibits the reaction [cobaltous chloride results in increased activity of CASP3 protein]; ginsenoside Rg1 promotes the reaction [Doxorubicin results in increased expression of CASP3 mRNA]
ginsenoside Rg1 inhibits the reaction [Chlorpyrifos results in increased cleavage of CASP3 protein]
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [ginsenoside Rg1 inhibits the reaction [Lipopolysaccharides results in increased cleavage of CASP3 protein]]; ginsenoside Rg1 inhibits the reaction [Lipopolysaccharides results in increased cleavage of CASP3 protein]
ginsenoside Rg1 results in increased activity of CASP3 protein		 CTD PMID:24386346 PMID:28371286 PMID:34783124 PMID:34859534 PMID:36811218 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062 		JBrowse link
G CASP9 caspase 9 increases activity
multiple interactions		 ISO
EXP		 ginsenoside Rg1 results in increased activity of CASP9 protein
ginsenoside Rg1 inhibits the reaction [Chlorpyrifos results in increased cleavage of CASP9 protein]
ginsenoside Rg1 promotes the reaction [Doxorubicin results in increased expression of CASP9 mRNA]
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [ginsenoside Rg1 inhibits the reaction [Lipopolysaccharides results in increased cleavage of CASP9 protein]]; ginsenoside Rg1 inhibits the reaction [Lipopolysaccharides results in increased cleavage of CASP9 protein]		 CTD PMID:28371286 PMID:34783124 PMID:34859534 PMID:36811218 NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534 		JBrowse link
G CAT catalase multiple interactions ISO ginsenoside Rg1 inhibits the reaction [Carbon Tetrachloride results in decreased activity of CAT protein]
ginsenoside Rg1 inhibits the reaction [Oxygen deficiency results in decreased expression of CAT protein]		 CTD PMID:29964319 PMID:37923178 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060 		JBrowse link
G CCNE1 cyclin E1 multiple interactions EXP ginsenoside Rg1 affects the reaction [tert-Butylhydroperoxide affects the expression of CCNE1 protein] CTD PMID:15606011 NCBI chr19:29,811,991...29,824,312
Ensembl chr19:29,811,991...29,824,312 		JBrowse link
G CDH1 cadherin 1 multiple interactions ISO ginsenoside Rg1 inhibits the reaction [Dibutyl Phthalate results in decreased expression of CDH1 mRNA]; ginsenoside Rg1 inhibits the reaction [Dibutyl Phthalate results in decreased expression of CDH1 protein] CTD PMID:33331133 NCBI chr16:68,737,292...68,835,537
Ensembl chr16:68,737,292...68,835,537 		JBrowse link
G CDK2 cyclin dependent kinase 2 multiple interactions EXP ginsenoside Rg1 affects the reaction [tert-Butylhydroperoxide affects the expression of CDK2 protein] CTD PMID:15606011 NCBI chr12:55,966,830...55,972,789
Ensembl chr12:55,966,781...55,972,789 		JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A multiple interactions EXP ginsenoside Rg1 affects the reaction [tert-Butylhydroperoxide affects the expression of CDKN1A protein]; ginsenoside Rg1 promotes the reaction [Doxorubicin results in increased expression of CDKN1A mRNA] CTD PMID:15606011 PMID:34783124 NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,337 		JBrowse link
G CREB1 cAMP responsive element binding protein 1 multiple interactions ISO ginsenoside Rg1 inhibits the reaction [Dibutyl Phthalate results in decreased expression of CREB1 protein] CTD PMID:33331133 NCBI chr 2:207,529,962...207,605,988
Ensembl chr 2:207,529,737...207,605,988 		JBrowse link
G CYP2B6 cytochrome P450 family 2 subfamily B member 6 multiple interactions ISO ginsenoside Rg1 inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of CYP2B10 mRNA]; ginsenoside Rg1 inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of CYP2B10 protein] CTD PMID:32198087 NCBI chr19:40,991,282...41,018,398
Ensembl chr19:40,991,282...41,018,398 		JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 multiple interactions ISO ginsenoside Rg1 inhibits the reaction [Carbon Tetrachloride results in increased expression of CYP2E1 mRNA] CTD PMID:29964319 NCBI chr10:133,527,363...133,539,123
Ensembl chr10:133,520,406...133,561,220 		JBrowse link
G CYP3A4 cytochrome P450 family 3 subfamily A member 4 multiple interactions ISO ginsenoside Rg1 inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of CYP3A4 mRNA]; ginsenoside Rg1 inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of CYP3A4 protein] CTD PMID:32198087 NCBI chr 7:99,756,967...99,784,184
Ensembl chr 7:99,756,960...99,784,248 		JBrowse link
G DDIT3 DNA damage inducible transcript 3 multiple interactions EXP ginsenoside Rg1 inhibits the reaction [Lipopolysaccharides results in increased expression of DDIT3 protein] CTD PMID:30918470 NCBI chr12:57,516,588...57,520,517
Ensembl chr12:57,516,588...57,521,737 		JBrowse link
G EIF4BP1 eukaryotic translation initiation factor 4B pseudogene 1 increases phosphorylation EXP ginsenoside Rg1 results in increased phosphorylation of EIF4BP1 protein CTD PMID:24386346 NCBI chr14:44,077,336...44,077,882
Ensembl chr14:44,077,534...44,077,884 		JBrowse link
G ERN1 endoplasmic reticulum to nucleus signaling 1 multiple interactions EXP ginsenoside Rg1 inhibits the reaction [Lipopolysaccharides results in increased expression of ERN1 protein] CTD PMID:30918470 NCBI chr17:64,039,142...64,130,144
Ensembl chr17:64,039,080...64,130,819 		JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit increases expression EXP ginsenoside Rg1 results in increased expression of FOS mRNA CTD PMID:16204943 NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,282,230 		JBrowse link
G FSHB follicle stimulating hormone subunit beta multiple interactions ISO ginsenoside Rg1 inhibits the reaction [Dibutyl Phthalate results in increased expression of FSHB protein] CTD PMID:33331133 NCBI chr11:30,231,014...30,235,194
Ensembl chr11:30,231,014...30,235,261 		JBrowse link
G FSHR follicle stimulating hormone receptor multiple interactions ISO ginsenoside Rg1 inhibits the reaction [Dibutyl Phthalate results in decreased expression of FSHR protein] CTD PMID:33331133 NCBI chr 2:48,962,157...49,154,515
Ensembl chr 2:48,962,157...49,154,527 		JBrowse link
G GCLC glutamate-cysteine ligase catalytic subunit increases expression
multiple interactions		 ISO ginsenoside Rg1 results in increased expression of GCLC mRNA
ginsenoside Rg1 inhibits the reaction [Carbon Tetrachloride results in decreased expression of GCLC mRNA]; NFE2L2 protein affects the reaction [ginsenoside Rg1 inhibits the reaction [Carbon Tetrachloride results in decreased expression of GCLC mRNA]]		 CTD PMID:29964319 NCBI chr 6:53,497,341...53,545,101
Ensembl chr 6:53,497,341...53,616,970 		JBrowse link
G GCLM glutamate-cysteine ligase modifier subunit increases expression
multiple interactions		 ISO ginsenoside Rg1 results in increased expression of GCLM protein
ginsenoside Rg1 inhibits the reaction [Carbon Tetrachloride results in decreased expression of GCLM protein]		 CTD PMID:29964319 NCBI chr 1:93,885,199...93,909,430
Ensembl chr 1:93,885,199...93,909,456 		JBrowse link
G GJA1 gap junction protein alpha 1 multiple interactions ISO ginsenoside Rg1 inhibits the reaction [Dibutyl Phthalate results in decreased expression of GJA1 mRNA]; ginsenoside Rg1 inhibits the reaction [Dibutyl Phthalate results in decreased expression of GJA1 protein] CTD PMID:33331133 NCBI chr 6:121,435,646...121,449,727
Ensembl chr 6:121,435,595...121,449,727 		JBrowse link
G GLUD1 glutamate dehydrogenase 1 multiple interactions ISO ginsenoside Rg1 inhibits the reaction [Oxygen deficiency results in increased expression of GLUD1 protein] CTD PMID:26593335 NCBI chr10:87,050,202...87,094,843
Ensembl chr10:87,050,202...87,094,843 		JBrowse link
G GPT glutamic--pyruvic transaminase multiple interactions ISO ginsenoside Rg1 inhibits the reaction [Carbon Tetrachloride results in increased expression of GPT protein] CTD PMID:29964319 NCBI chr 8:144,503,068...144,507,172
Ensembl chr 8:144,502,973...144,507,174 		JBrowse link
G GSK3B glycogen synthase kinase 3 beta multiple interactions ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [ginsenoside Rg1 inhibits the reaction [Lipopolysaccharides results in decreased phosphorylation of GSK3B protein]]; ginsenoside Rg1 inhibits the reaction [Lipopolysaccharides results in decreased phosphorylation of GSK3B protein] CTD PMID:34859534 NCBI chr 3:119,821,321...120,094,447
Ensembl chr 3:119,821,321...120,094,994 		JBrowse link
G H2AX H2A.X variant histone multiple interactions EXP ginsenoside Rg1 promotes the reaction [Doxorubicin results in increased expression of H2AX mRNA] CTD PMID:34783124 NCBI chr11:119,093,874...119,095,465
Ensembl chr11:119,093,874...119,095,465 		JBrowse link
G HMOX1 heme oxygenase 1 multiple interactions
increases expression		 ISO [astragaloside A co-treated with ginsenoside Rg1 co-treated with ginsenoside Rb1 co-treated with notoginsenoside R1] results in increased expression of HMOX1 mRNA; [astragaloside A co-treated with ginsenoside Rg1 co-treated with ginsenoside Rb1 co-treated with notoginsenoside R1] results in increased expression of HMOX1 protein; ginsenoside Rg1 inhibits the reaction [Carbon Tetrachloride results in decreased expression of HMOX1 mRNA]; NFE2L2 protein affects the reaction [ginsenoside Rg1 inhibits the reaction [Carbon Tetrachloride results in decreased expression of HMOX1 mRNA]]; Tretinoin inhibits the reaction [ginsenoside Rg1 inhibits the reaction [Carbon Tetrachloride results in decreased expression of HMOX1 mRNA]]
ginsenoside Rg1 results in increased expression of HMOX1 mRNA; ginsenoside Rg1 results in increased expression of HMOX1 protein		 CTD PMID:25422538 PMID:29964319 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214 		JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 multiple interactions EXP ginsenoside Rg1 inhibits the reaction [Lipopolysaccharides results in increased expression of HSPA5 protein] CTD PMID:30918470 NCBI chr 9:125,234,853...125,241,343
Ensembl chr 9:125,234,853...125,241,382 		JBrowse link
G IFNG interferon gamma multiple interactions ISO ginsenoside Rg1 inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of IFNG protein] CTD PMID:32198087 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740 		JBrowse link
G IL1B interleukin 1 beta multiple interactions ISO 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [ginsenoside Rg1 inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B]]; ginsenoside Rg1 inhibits the reaction [Carbon Tetrachloride results in increased expression of IL1B protein]; ginsenoside Rg1 inhibits the reaction [Chlorpyrifos results in increased expression of IL1B protein]; ginsenoside Rg1 inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B]
ginsenoside Rg1 inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of IL1B protein]		 CTD PMID:22214447 PMID:29964319 PMID:32198087 PMID:36811218 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL6 interleukin 6 multiple interactions ISO
EXP		 ginsenoside Rg1 inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]; ginsenoside Rg1 inhibits the reaction [Oxygen deficiency results in increased expression of IL6 protein]
ginsenoside Rg1 inhibits the reaction [Carbon Tetrachloride results in increased expression of IL6 protein]; ginsenoside Rg1 inhibits the reaction [Chlorpyrifos results in increased expression of IL6 protein]; ginsenoside Rg1 inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]		 CTD PMID:17655881 PMID:29964319 PMID:30918470 PMID:36811218 PMID:37923178 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G INHA inhibin subunit alpha multiple interactions ISO ginsenoside Rg1 inhibits the reaction [Dibutyl Phthalate results in decreased expression of INHA protein] CTD PMID:33331133 NCBI chr 2:219,572,310...219,575,711
Ensembl chr 2:219,569,162...219,575,711 		JBrowse link
G KCNH2 potassium voltage-gated channel subfamily H member 2 affects activity EXP ginsenoside Rg1 affects the activity of KCNH2 protein CTD PMID:15842772 NCBI chr 7:150,944,961...150,978,321
Ensembl chr 7:150,944,961...150,978,321 		JBrowse link
G KEAP1 kelch like ECH associated protein 1 multiple interactions ISO ginsenoside Rg1 inhibits the reaction [Carbon Tetrachloride results in increased expression of KEAP1 protein] CTD PMID:29964319 NCBI chr19:10,486,125...10,503,356
Ensembl chr19:10,486,125...10,503,558 		JBrowse link
G LHB luteinizing hormone subunit beta multiple interactions ISO ginsenoside Rg1 inhibits the reaction [Dibutyl Phthalate results in decreased expression of LHB protein] CTD PMID:33331133 NCBI chr19:49,015,980...49,019,498
Ensembl chr19:49,015,980...49,017,091 		JBrowse link
G LPL lipoprotein lipase increases secretion ISO ginsenoside Rg1 results in increased secretion of LPL protein CTD PMID:8988629 NCBI chr 8:19,939,253...19,967,259
Ensembl chr 8:19,901,717...19,967,259 		JBrowse link
G MAP2 microtubule associated protein 2 increases expression ISO ginsenoside Rg1 results in increased expression of MAP2 mRNA CTD PMID:24599032 NCBI chr 2:209,424,047...209,734,112
Ensembl chr 2:209,424,047...209,734,147 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 multiple interactions
affects phosphorylation		 ISO PLCG1 affects the reaction [ginsenoside Rg1 affects the phosphorylation of MAPK1 protein] CTD PMID:22214447 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 affects phosphorylation
multiple interactions		 ISO ginsenoside Rg1 affects the phosphorylation of MAPK3 protein
PLCG1 affects the reaction [ginsenoside Rg1 affects the phosphorylation of MAPK3 protein]		 CTD PMID:22214447 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506 		JBrowse link
G MAPK8 mitogen-activated protein kinase 8 multiple interactions EXP ginsenoside Rg1 inhibits the reaction [cobaltous chloride results in increased phosphorylation of MAPK8 protein] CTD PMID:24386346 NCBI chr10:48,306,677...48,439,360
Ensembl chr10:48,306,639...48,439,360 		JBrowse link
G MAPK9 mitogen-activated protein kinase 9 multiple interactions EXP ginsenoside Rg1 inhibits the reaction [cobaltous chloride results in increased phosphorylation of MAPK9 protein] CTD PMID:24386346 NCBI chr 5:180,233,143...180,292,083
Ensembl chr 5:180,233,143...180,292,099 		JBrowse link
G MET MET proto-oncogene, receptor tyrosine kinase multiple interactions
increases expression		 EXP Mifepristone inhibits the reaction [ginsenoside Rg1 results in increased expression of MET protein]; MIR23A mRNA inhibits the reaction [ginsenoside Rg1 results in increased expression of MET protein] CTD PMID:26115870 NCBI chr 7:116,672,196...116,798,377
Ensembl chr 7:116,672,196...116,798,377 		JBrowse link
G MFN2 mitofusin 2 multiple interactions ISO ginsenoside Rg1 inhibits the reaction [Oxygen deficiency results in decreased expression of MFN2 mRNA]; ginsenoside Rg1 inhibits the reaction [Oxygen deficiency results in decreased expression of MFN2 protein] CTD PMID:26593335 NCBI chr 1:11,980,444...12,013,508
Ensembl chr 1:11,980,181...12,015,211 		JBrowse link
G MIR23A microRNA 23a decreases expression
multiple interactions		 EXP ginsenoside Rg1 results in decreased expression of MIR23A mRNA
Mifepristone inhibits the reaction [ginsenoside Rg1 results in decreased expression of MIR23A mRNA]; MIR23A mRNA inhibits the reaction [ginsenoside Rg1 results in increased expression of MET protein]		 CTD PMID:26115870 NCBI chr19:13,836,587...13,836,659
Ensembl chr19:13,836,587...13,836,659 		JBrowse link
G MMP2 matrix metallopeptidase 2 increases expression ISO ginsenoside Rg1 results in increased expression of MMP2 protein CTD PMID:23738715 NCBI chr16:55,478,830...55,506,691
Ensembl chr16:55,389,700...55,506,691 		JBrowse link
G MMP9 matrix metallopeptidase 9 increases expression ISO ginsenoside Rg1 results in increased expression of MMP9 protein CTD PMID:23738715 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561 		JBrowse link
G MTOR mechanistic target of rapamycin kinase multiple interactions EXP
ISO		 ginsenoside Rg1 inhibits the reaction [cobaltous chloride results in decreased activity of [MTOR protein binds to RAPTOR protein]]; ginsenoside Rg1 results in increased activity of [MTOR protein binds to RAPTOR protein]
ginsenoside Rg1 inhibits the reaction [Dibutyl Phthalate results in decreased expression of MTOR protein]		 CTD PMID:24386346 PMID:33331133 NCBI chr 1:11,106,535...11,262,551
Ensembl chr 1:11,106,535...11,262,556 		JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 multiple interactions
affects localization
increases expression		 EXP
ISO		 [ginsenoside Rg1 co-treated with ginsenoside 20S-protopanaxatriol] results in increased expression of NFE2L2 protein
ginsenoside Rg1 affects the localization of NFE2L2 protein
[astragaloside A co-treated with ginsenoside Rg1 co-treated with ginsenoside Rb1 co-treated with notoginsenoside R1] affects the localization of NFE2L2 protein; ginsenoside Rg1 inhibits the reaction [Carbon Tetrachloride results in decreased expression of NFE2L2 protein]; NFE2L2 protein affects the reaction [ginsenoside Rg1 inhibits the reaction [Carbon Tetrachloride results in decreased expression of GCLC mRNA]]; NFE2L2 protein affects the reaction [ginsenoside Rg1 inhibits the reaction [Carbon Tetrachloride results in decreased expression of HMOX1 mRNA]]; NFE2L2 protein affects the reaction [ginsenoside Rg1 inhibits the reaction [Carbon Tetrachloride results in decreased expression of NQO1 mRNA]]; Tretinoin inhibits the reaction [ginsenoside Rg1 inhibits the reaction [Carbon Tetrachloride results in decreased expression of NFE2L2 protein]]
ginsenoside Rg1 results in increased expression of NFE2L2 mRNA		 CTD PMID:22780686 PMID:25422538 PMID:29964319 NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756 		JBrowse link
G NFKBIA NFKB inhibitor alpha affects phosphorylation
multiple interactions		 ISO ginsenoside Rg1 affects the phosphorylation of NFKBIA protein
PLCG1 affects the reaction [ginsenoside Rg1 affects the phosphorylation of NFKBIA protein]		 CTD PMID:22214447 NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749 		JBrowse link
G NOS2 nitric oxide synthase 2 multiple interactions ISO 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [ginsenoside Rg1 inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2]]; ginsenoside Rg1 inhibits the reaction [Carbon Tetrachloride results in increased expression of NOS2 protein]; ginsenoside Rg1 inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2] CTD PMID:22214447 PMID:29964319 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529 		JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 multiple interactions ISO ginsenoside Rg1 inhibits the reaction [Carbon Tetrachloride results in decreased expression of NQO1 mRNA]; ginsenoside Rg1 inhibits the reaction [Carbon Tetrachloride results in decreased expression of NQO1 protein]; NFE2L2 protein affects the reaction [ginsenoside Rg1 inhibits the reaction [Carbon Tetrachloride results in decreased expression of NQO1 mRNA]]; Tretinoin inhibits the reaction [ginsenoside Rg1 inhibits the reaction [Carbon Tetrachloride results in decreased expression of NQO1 mRNA]] CTD PMID:29964319 NCBI chr16:69,709,401...69,726,560
Ensembl chr16:69,706,996...69,726,668 		JBrowse link
G NR1H4 nuclear receptor subfamily 1 group H member 4 multiple interactions ISO ginsenoside Rg1 inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of NR1H4 mRNA]; ginsenoside Rg1 inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of NR1H4 protein] CTD PMID:32198087 NCBI chr12:100,473,866...100,564,414
Ensembl chr12:100,473,708...100,564,414 		JBrowse link
G PGR progesterone receptor increases expression EXP ginsenoside Rg1 results in increased expression of PGR protein CTD PMID:16204943 NCBI chr11:101,029,624...101,129,813
Ensembl chr11:101,029,624...101,129,813 		JBrowse link
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha multiple interactions ISO ginsenoside Rg1 inhibits the reaction [Dibutyl Phthalate results in decreased expression of PIK3CA mRNA] CTD PMID:33331133 NCBI chr 3:179,148,126...179,240,093
Ensembl chr 3:179,148,114...179,240,093 		JBrowse link
G PLCG1 phospholipase C gamma 1 multiple interactions ISO PLCG1 affects the reaction [ginsenoside Rg1 affects the phosphorylation of MAPK1 protein]; PLCG1 affects the reaction [ginsenoside Rg1 affects the phosphorylation of MAPK3 protein]; PLCG1 affects the reaction [ginsenoside Rg1 affects the phosphorylation of NFKBIA protein] CTD PMID:22214447 NCBI chr20:41,137,543...41,177,626
Ensembl chr20:41,136,960...41,196,801 		JBrowse link
G PRKAA1 protein kinase AMP-activated catalytic subunit alpha 1 multiple interactions EXP ginsenoside Rg1 inhibits the reaction [cobaltous chloride results in increased phosphorylation of PRKAA1 protein] CTD PMID:24386346 NCBI chr 5:40,759,389...40,798,374
Ensembl chr 5:40,759,389...40,798,374 		JBrowse link
G PTEN phosphatase and tensin homolog multiple interactions ISO ginsenoside Rg1 inhibits the reaction [Dibutyl Phthalate results in increased expression of PTEN protein] CTD PMID:33331133 NCBI chr10:87,863,625...87,971,930
Ensembl chr10:87,862,638...87,971,930 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [ginsenoside Rg1 inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2]]; ginsenoside Rg1 inhibits the reaction [Carbon Tetrachloride results in increased expression of PTGS2 protein]; ginsenoside Rg1 inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2] CTD PMID:22214447 PMID:29964319 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922 		JBrowse link
G RAD51 RAD51 recombinase multiple interactions EXP ginsenoside Rg1 promotes the reaction [Doxorubicin results in increased expression of RAD51 mRNA] CTD PMID:34783124 NCBI chr15:40,694,733...40,732,340
Ensembl chr15:40,694,774...40,732,340 		JBrowse link
G RPS6 ribosomal protein S6 increases phosphorylation EXP ginsenoside Rg1 results in increased phosphorylation of RPS6 protein CTD PMID:24386346 NCBI chr 9:19,375,715...19,380,236
Ensembl chr 9:19,375,715...19,380,236 		JBrowse link
G RPTOR regulatory associated protein of MTOR complex 1 multiple interactions EXP ginsenoside Rg1 inhibits the reaction [cobaltous chloride results in decreased activity of [MTOR protein binds to RAPTOR protein]]; ginsenoside Rg1 results in increased activity of [MTOR protein binds to RAPTOR protein] CTD PMID:24386346 NCBI chr17:80,544,838...80,966,368
Ensembl chr17:80,544,819...80,966,371 		JBrowse link
G SIRT1 sirtuin 1 multiple interactions EXP ginsenoside Rg1 inhibits the reaction [Lipopolysaccharides results in increased expression of SIRT1 protein] CTD PMID:30918470 NCBI chr10:67,884,656...67,918,390
Ensembl chr10:67,884,656...67,918,390 		JBrowse link
G SLC10A1 solute carrier family 10 member 1 multiple interactions ISO ginsenoside Rg1 inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of SLC10A1 mRNA]; ginsenoside Rg1 inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of SLC10A1 protein] CTD PMID:32198087 NCBI chr14:69,775,416...69,797,241
Ensembl chr14:69,775,416...69,797,241 		JBrowse link
G SLCO1B3 solute carrier organic anion transporter family member 1B3 multiple interactions EXP
ISO		 SLCO1B3 protein binds to and results in increased transport of ginsenoside Rg1
SLCO1B2 protein binds to and results in increased transport of ginsenoside Rg1		 CTD PMID:25297453 NCBI chr12:20,810,705...20,916,911
Ensembl chr12:20,810,702...20,916,911 		JBrowse link
G SOD1 superoxide dismutase 1 multiple interactions ISO ginsenoside Rg1 inhibits the reaction [Oxygen deficiency results in decreased expression of SOD1 protein] CTD PMID:37923178 NCBI chr21:31,659,693...31,668,931
Ensembl chr21:31,659,666...31,668,931 		JBrowse link
G SULT2A1 sulfotransferase family 2A member 1 multiple interactions ISO ginsenoside Rg1 inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of SULT2A1 mRNA]; ginsenoside Rg1 inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of SULT2A1 protein] CTD PMID:32198087 NCBI chr19:47,870,467...47,886,315
Ensembl chr19:47,870,467...47,886,315 		JBrowse link
G TFF1 trefoil factor 1 increases expression EXP ginsenoside Rg1 results in increased expression of TFF1 mRNA CTD PMID:16204943 NCBI chr21:42,362,282...42,366,535
Ensembl chr21:42,362,282...42,366,535 		JBrowse link
G TNF tumor necrosis factor multiple interactions ISO
EXP		 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [ginsenoside Rg1 inhibits the reaction [Lipopolysaccharides results in increased expression of TNF]]; ginsenoside Rg1 inhibits the reaction [Carbon Tetrachloride results in increased expression of TNF protein]; ginsenoside Rg1 inhibits the reaction [Chlorpyrifos results in increased expression of TNF protein]; ginsenoside Rg1 inhibits the reaction [Lipopolysaccharides results in increased expression of TNF]; ginsenoside Rg1 inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]
ginsenoside Rg1 inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of TNF protein]; ginsenoside Rg1 inhibits the reaction [Oxygen deficiency results in increased expression of TNF protein]		 CTD PMID:22214447 PMID:29964319 PMID:30918470 PMID:32198087 PMID:36811218 More... NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TP53 tumor protein p53 multiple interactions EXP ginsenoside Rg1 promotes the reaction [Doxorubicin results in increased expression of TP53 mRNA] CTD PMID:34783124 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,546 		JBrowse link
G UGT1A1 UDP glucuronosyltransferase family 1 member A1 multiple interactions ISO ginsenoside Rg1 inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of UGT1A1 mRNA]; ginsenoside Rg1 inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of UGT1A1 protein] CTD PMID:32198087 NCBI chr 2:233,760,270...233,773,300
Ensembl chr 2:233,760,270...233,773,300 		JBrowse link
G XRCC1 X-ray repair cross complementing 1 multiple interactions EXP ginsenoside Rg1 promotes the reaction [Doxorubicin results in increased expression of XRCC1 mRNA] CTD PMID:34783124 NCBI chr19:43,543,311...43,575,527
Ensembl chr19:43,543,311...43,580,473 		JBrowse link
ginsenoside Rg2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCC2 ATP binding cassette subfamily C member 2 increases expression ISO ginsenoside Rg2 results in increased expression of ABCC2 mRNA CTD PMID:23835644 NCBI chr10:99,782,640...99,852,594
Ensembl chr10:99,782,640...99,852,594 		JBrowse link
G AKT1 AKT serine/threonine kinase 1 multiple interactions ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [ginsenoside Rg2 inhibits the reaction [APP protein modified form results in decreased phosphorylation of AKT1 protein]]; ginsenoside Rg2 inhibits the reaction [APP protein modified form results in decreased phosphorylation of AKT1 protein] CTD PMID:28756148 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,759 		JBrowse link
G APP amyloid beta precursor protein multiple interactions ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [ginsenoside Rg2 inhibits the reaction [APP protein modified form results in decreased phosphorylation of AKT1 protein]]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [ginsenoside Rg2 inhibits the reaction [APP protein modified form results in increased activity of CASP3 protein]]; ginsenoside Rg2 inhibits the reaction [APP protein modified form results in decreased expression of BCL2 protein]; ginsenoside Rg2 inhibits the reaction [APP protein modified form results in decreased phosphorylation of AKT1 protein]; ginsenoside Rg2 inhibits the reaction [APP protein modified form results in increased activity of and results in increased cleavage of CASP3 protein]; ginsenoside Rg2 inhibits the reaction [APP protein modified form results in increased expression of BAX protein] CTD PMID:28756148 NCBI chr21:25,880,550...26,171,128
Ensembl chr21:25,880,535...26,171,128 		JBrowse link
G BAX BCL2 associated X, apoptosis regulator multiple interactions ISO ginsenoside Rg2 inhibits the reaction [APP protein modified form results in increased expression of BAX protein] CTD PMID:28756148 NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798 		JBrowse link
G BCL2 BCL2 apoptosis regulator multiple interactions ISO ginsenoside Rg2 inhibits the reaction [APP protein modified form results in decreased expression of BCL2 protein] CTD PMID:28756148 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128 		JBrowse link
G BECN2 beclin 2 multiple interactions ISO
EXP		 ginsenoside Rg2 inhibits the reaction [BECN2 protein binds to GPRASP1 protein] CTD PMID:27305347 NCBI chr 1:241,957,767...241,959,062
Ensembl chr 1:241,957,767...241,959,062 		JBrowse link
G CASP3 caspase 3 multiple interactions ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [ginsenoside Rg2 inhibits the reaction [APP protein modified form results in increased activity of CASP3 protein]]; ginsenoside Rg2 inhibits the reaction [APP protein modified form results in increased activity of and results in increased cleavage of CASP3 protein] CTD PMID:28756148 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062 		JBrowse link
G CRTC2 CREB regulated transcription coactivator 2 multiple interactions EXP [ginsenoside Rg2 results in increased activity of NR0B2 protein] which results in decreased activity of CRTC2 protein CTD PMID:22062806 NCBI chr 1:153,947,675...153,958,612
Ensembl chr 1:153,947,669...153,958,615 		JBrowse link
G G6PC3 glucose-6-phosphatase catalytic subunit 3 decreases expression
multiple interactions		 EXP ginsenoside Rg2 results in decreased expression of G6PC3 mRNA
dorsomorphin inhibits the reaction [ginsenoside Rg2 results in decreased expression of G6PC3 mRNA]		 CTD PMID:22062806 NCBI chr17:44,070,673...44,076,344
Ensembl chr17:44,070,620...44,082,151 		JBrowse link
G GPRASP1 G protein-coupled receptor associated sorting protein 1 multiple interactions EXP
ISO		 ginsenoside Rg2 inhibits the reaction [BECN2 protein binds to GPRASP1 protein] CTD PMID:27305347 NCBI chr  X:102,651,483...102,659,083
Ensembl chr  X:102,651,092...102,659,083 		JBrowse link
G GSK3B glycogen synthase kinase 3 beta increases phosphorylation
multiple interactions		 EXP ginsenoside Rg2 results in increased phosphorylation of GSK3B protein
[[ginsenoside Rg2 results in increased phosphorylation of GSK3B protein] co-treated with [ginsenoside Rg2 results in increased expression of NR0B2 mRNA]] results in decreased chemical synthesis of Glucose; dorsomorphin inhibits the reaction [ginsenoside Rg2 results in increased phosphorylation of GSK3B protein]		 CTD PMID:22062806 NCBI chr 3:119,821,321...120,094,447
Ensembl chr 3:119,821,321...120,094,994 		JBrowse link
G MAP1LC3B microtubule associated protein 1 light chain 3 beta multiple interactions
increases expression		 EXP bafilomycin A1 promotes the reaction [ginsenoside Rg2 results in increased expression of MAP1LC3B protein modified form] CTD PMID:27305347 NCBI chr16:87,392,336...87,404,774
Ensembl chr16:87,383,953...87,404,779 		JBrowse link
G NR0B2 nuclear receptor subfamily 0 group B member 2 multiple interactions
increases expression
increases activity		 EXP [[ginsenoside Rg2 results in increased phosphorylation of GSK3B protein] co-treated with [ginsenoside Rg2 results in increased expression of NR0B2 mRNA]] results in decreased chemical synthesis of Glucose; [ginsenoside Rg2 results in increased activity of NR0B2 protein] which results in decreased activity of CRTC2 protein CTD PMID:22062806 NCBI chr 1:26,911,489...26,913,975
Ensembl chr 1:26,911,489...26,913,975 		JBrowse link
G PCK1 phosphoenolpyruvate carboxykinase 1 multiple interactions
decreases expression		 EXP dorsomorphin inhibits the reaction [ginsenoside Rg2 results in decreased expression of PCK1 mRNA] CTD PMID:22062806 NCBI chr20:57,561,110...57,568,121
Ensembl chr20:57,561,080...57,568,121 		JBrowse link
G PPARGC1A PPARG coactivator 1 alpha multiple interactions
decreases expression		 EXP dorsomorphin inhibits the reaction [ginsenoside Rg2 results in decreased expression of PPARGC1A mRNA] CTD PMID:22062806 NCBI chr 4:23,792,021...24,472,905
Ensembl chr 4:23,755,041...23,904,089 		JBrowse link
G SQSTM1 sequestosome 1 multiple interactions
decreases expression		 EXP
ISO		 bafilomycin A1 promotes the reaction [ginsenoside Rg2 results in decreased expression of SQSTM1 protein] CTD PMID:27305347 NCBI chr 5:179,806,393...179,838,078
Ensembl chr 5:179,806,398...179,838,078 		JBrowse link
G STK11 serine/threonine kinase 11 increases phosphorylation
multiple interactions		 EXP ginsenoside Rg2 results in increased phosphorylation of STK11 protein
dorsomorphin inhibits the reaction [ginsenoside Rg2 results in increased phosphorylation of STK11 protein]		 CTD PMID:22062806 NCBI chr19:1,205,778...1,228,431
Ensembl chr19:1,177,558...1,228,431 		JBrowse link
glucobrassicin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GPX2 glutathione peroxidase 2 multiple interactions
decreases expression		 EXP glucobrassicin analog inhibits the reaction [glucoraphanin analog results in increased expression of GPX2 mRNA]
glucobrassicin analog results in decreased expression of GPX2 protein		 CTD PMID:20868228 NCBI chr14:64,939,158...64,942,745
Ensembl chr14:64,939,152...64,942,746 		JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 multiple interactions
decreases activity		 EXP glucobrassicin analog inhibits the reaction [glucoraphanin results in increased activity of NQO1 protein]
glucobrassicin analog results in decreased activity of NQO1 protein		 CTD PMID:20868228 NCBI chr16:69,709,401...69,726,560
Ensembl chr16:69,706,996...69,726,668 		JBrowse link
glucoerucin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 increases expression ISO glucoerucin results in increased expression of CYP1A1 protein CTD PMID:20833222 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536 		JBrowse link
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 increases expression ISO glucoerucin results in increased expression of CYP1A2 protein CTD PMID:20833222 NCBI chr15:74,748,845...74,756,607
Ensembl chr15:74,748,845...74,756,607 		JBrowse link
G CYP1B1 cytochrome P450 family 1 subfamily B member 1 increases expression ISO glucoerucin results in increased expression of CYP1B1 protein CTD PMID:20833222 NCBI chr 2:38,067,509...38,076,151
Ensembl chr 2:38,066,973...38,109,902 		JBrowse link
G EPHX1 epoxide hydrolase 1 increases expression ISO glucoerucin results in increased expression of EPHX1 protein CTD PMID:21132492 NCBI chr 1:225,810,124...225,845,563
Ensembl chr 1:225,810,124...225,845,563 		JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 increases activity ISO glucoerucin results in increased activity of NQO1 protein CTD PMID:20833222 NCBI chr16:69,709,401...69,726,560
Ensembl chr16:69,706,996...69,726,668 		JBrowse link
glucoraphanin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 increases expression ISO glucoraphanin results in increased expression of CYP1A1 protein CTD PMID:20833222 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536 		JBrowse link
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 increases expression ISO glucoraphanin results in increased expression of CYP1A2 protein CTD PMID:20833222 NCBI chr15:74,748,845...74,756,607
Ensembl chr15:74,748,845...74,756,607 		JBrowse link
G CYP1B1 cytochrome P450 family 1 subfamily B member 1 increases expression ISO glucoraphanin results in increased expression of CYP1B1 protein CTD PMID:20833222 NCBI chr 2:38,067,509...38,076,151
Ensembl chr 2:38,066,973...38,109,902 		JBrowse link
G EPHX1 epoxide hydrolase 1 increases expression ISO glucoraphanin results in increased expression of EPHX1 protein CTD PMID:21132492 NCBI chr 1:225,810,124...225,845,563
Ensembl chr 1:225,810,124...225,845,563 		JBrowse link
G GPX1 glutathione peroxidase 1 decreases expression ISO Glucoraphanin decreases expression of Gpx1 mRNA in the jejunum RGD PMID:23271678 RGD:152998882 NCBI chr 3:49,357,176...49,358,353
Ensembl chr 3:49,357,174...49,358,605 		JBrowse link
G GPX2 glutathione peroxidase 2 increases expression
increases expression
multiple interactions		 EXP
ISO		 glucoraphanin analog results in increased expression of GPX2 mRNA; glucoraphanin analog results in increased expression of GPX2 protein
Glucoraphanin increases expression of Gpx2 mRNA in the jejunum
Benzo(a)pyrene inhibits the reaction [glucoraphanin results in increased expression of GPX2 mRNA]; glucobrassicin analog inhibits the reaction [glucoraphanin analog results in increased expression of GPX2 mRNA]		 CTD
RGD		 PMID:20868228 PMID:23271678 RGD:152998882 NCBI chr14:64,939,158...64,942,745
Ensembl chr14:64,939,152...64,942,746 		JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 affects localization EXP glucoraphanin analog affects the localization of NFE2L2 protein CTD PMID:20868228 NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756 		JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 multiple interactions
increases activity		 EXP
ISO		 glucobrassicin analog inhibits the reaction [glucoraphanin results in increased activity of NQO1 protein]
glucoraphanin analog results in increased activity of NQO1 protein		 CTD PMID:20833222 PMID:20868228 NCBI chr16:69,709,401...69,726,560
Ensembl chr16:69,706,996...69,726,668 		JBrowse link
glycitin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACSL3 acyl-CoA synthetase long chain family member 3 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of ACSL3 mRNA CTD PMID:27424125 NCBI chr 2:222,861,036...222,944,639
Ensembl chr 2:222,860,942...222,944,639 		JBrowse link
G ALDH1A2 aldehyde dehydrogenase 1 family member A2 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of ALDH1A2 mRNA CTD PMID:27424125 NCBI chr15:57,953,429...58,065,711
Ensembl chr15:57,953,424...58,497,866 		JBrowse link
G ANPEP alanyl aminopeptidase, membrane multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of ANPEP mRNA CTD PMID:27424125 NCBI chr15:89,784,895...89,814,852
Ensembl chr15:89,784,895...89,815,401 		JBrowse link
G APP amyloid beta precursor protein multiple interactions ISO glycitin inhibits the reaction [APP protein binds to APP protein] CTD PMID:17323972 NCBI chr21:25,880,550...26,171,128
Ensembl chr21:25,880,535...26,171,128 		JBrowse link
G ATOH8 atonal bHLH transcription factor 8 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of ATOH8 mRNA CTD PMID:27424125 NCBI chr 2:85,753,991...85,791,383
Ensembl chr 2:85,751,344...85,791,383 		JBrowse link
G BCKDK branched chain keto acid dehydrogenase kinase multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of BCKDK mRNA CTD PMID:27424125 NCBI chr16:31,108,386...31,117,640
Ensembl chr16:31,106,107...31,112,791 		JBrowse link
G BPGM bisphosphoglycerate mutase multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of BPGM mRNA CTD PMID:27424125 NCBI chr 7:134,646,853...134,679,816
Ensembl chr 7:134,646,811...134,679,816 		JBrowse link
G CABP5 calcium binding protein 5 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of CABP5 mRNA CTD PMID:27424125 NCBI chr19:48,029,383...48,044,079
Ensembl chr19:48,029,383...48,044,079 		JBrowse link
G CACYBP calcyclin binding protein multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of CACYBP mRNA CTD PMID:27424125 NCBI chr 1:174,999,435...175,012,027
Ensembl chr 1:174,999,163...175,012,027 		JBrowse link
G CASP8AP2 caspase 8 associated protein 2 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of CASP8AP2 mRNA CTD PMID:27424125 NCBI chr 6:89,829,880...89,874,436
Ensembl chr 6:89,829,894...89,874,436 		JBrowse link
G CD200R1 CD200 receptor 1 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of CD200R1 mRNA CTD PMID:27424125 NCBI chr 3:112,921,205...112,975,103
Ensembl chr 3:112,921,205...112,975,103 		JBrowse link
G CFAP251 cilia and flagella associated protein 251 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of CFAP251 mRNA CTD PMID:27424125 NCBI chr12:121,918,592...122,003,919
Ensembl chr12:121,918,592...122,003,927 		JBrowse link
G CYBRD1 cytochrome b reductase 1 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of CYBRD1 mRNA CTD PMID:27424125 NCBI chr 2:171,522,233...171,558,129
Ensembl chr 2:171,522,247...171,558,129 		JBrowse link
G CYP11A1 cytochrome P450 family 11 subfamily A member 1 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of CYP11A1 mRNA CTD PMID:28964809 NCBI chr15:74,337,762...74,367,646
Ensembl chr15:74,337,759...74,367,646 		JBrowse link
G DENND2D DENN domain containing 2D multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of DENND2D mRNA CTD PMID:27424125 NCBI chr 1:111,185,969...111,204,578
Ensembl chr 1:111,185,969...111,204,535 		JBrowse link
G DNMT1 DNA methyltransferase 1 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in increased expression of DNMT1 mRNA CTD PMID:28964809 NCBI chr19:10,133,346...10,194,953
Ensembl chr19:10,133,342...10,231,286 		JBrowse link
G DNMT3A DNA methyltransferase 3 alpha multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in increased expression of DNMT3A mRNA CTD PMID:28964809 NCBI chr 2:25,227,874...25,342,590
Ensembl chr 2:25,227,855...25,342,590 		JBrowse link
G DPP9 dipeptidyl peptidase 9 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of DPP9 mRNA CTD PMID:27424125 NCBI chr19:4,675,227...4,723,842
Ensembl chr19:4,674,341...4,724,673 		JBrowse link
G EDRF1 erythroid differentiation regulatory factor 1 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of EDRF1 mRNA CTD PMID:27424125 NCBI chr10:125,719,709...125,764,139
Ensembl chr10:125,719,515...125,764,143 		JBrowse link
G EFHD1 EF-hand domain family member D1 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of EFHD1 mRNA CTD PMID:27424125 NCBI chr 2:232,606,057...232,682,776
Ensembl chr 2:232,606,057...232,682,776 		JBrowse link
G ESR2 estrogen receptor 2 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in increased expression of ESR2 mRNA CTD PMID:28964809 NCBI chr14:64,226,707...64,338,613
Ensembl chr14:64,084,232...64,338,112 		JBrowse link
G FAM171A2 family with sequence similarity 171 member A2 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of FAM171A2 mRNA CTD PMID:27424125 NCBI chr17:44,353,215...44,363,853
Ensembl chr17:44,353,215...44,363,853 		JBrowse link
G FAM180A family with sequence similarity 180 member A multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of FAM180A mRNA CTD PMID:27424125 NCBI chr 7:135,729,592...135,748,813
Ensembl chr 7:135,728,348...135,748,813 		JBrowse link
G FAM210B family with sequence similarity 210 member B multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of FAM210B mRNA CTD PMID:27424125 NCBI chr20:56,358,974...56,368,663
Ensembl chr20:56,358,974...56,368,663 		JBrowse link
G FAM241B family with sequence similarity 241 member B multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of FAM241B mRNA CTD PMID:27424125 NCBI chr10:69,630,247...69,633,596
Ensembl chr10:69,630,247...69,633,596 		JBrowse link
G FGD6 FYVE, RhoGEF and PH domain containing 6 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of FGD6 mRNA CTD PMID:27424125 NCBI chr12:95,076,749...95,217,467
Ensembl chr12:95,076,749...95,217,482 		JBrowse link
G FHL2 four and a half LIM domains 2 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of FHL2 mRNA CTD PMID:27424125 NCBI chr 2:105,357,712...105,438,529
Ensembl chr 2:105,357,712...105,438,513 		JBrowse link
G GALNT15 polypeptide N-acetylgalactosaminyltransferase 15 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of GALNT15 mRNA CTD PMID:27424125 NCBI chr 3:16,174,680...16,248,224
Ensembl chr 3:16,174,680...16,231,992 		JBrowse link
G GNG5 G protein subunit gamma 5 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of GNG5 mRNA CTD PMID:27424125 NCBI chr 1:84,498,325...84,506,581
Ensembl chr 1:84,498,323...84,506,581 		JBrowse link
G HIPK4 homeodomain interacting protein kinase 4 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of HIPK4 mRNA CTD PMID:27424125 NCBI chr19:40,379,271...40,390,181
Ensembl chr19:40,379,271...40,390,181 		JBrowse link
G HMCN1 hemicentin 1 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of HMCN1 mRNA CTD PMID:27424125 NCBI chr 1:185,734,391...186,190,949
Ensembl chr 1:185,734,391...186,190,949 		JBrowse link
G HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of HSD3B1 mRNA CTD PMID:28964809 NCBI chr 1:119,507,203...119,515,058
Ensembl chr 1:119,507,198...119,515,054 		JBrowse link
G IL6R interleukin 6 receptor multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of IL6R mRNA CTD PMID:27424125 NCBI chr 1:154,405,343...154,469,450
Ensembl chr 1:154,405,193...154,469,450 		JBrowse link
G ISG20L2 interferon stimulated exonuclease gene 20 like 2 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of ISG20L2 mRNA CTD PMID:27424125 NCBI chr 1:156,721,891...156,728,766
Ensembl chr 1:156,721,891...156,728,766 		JBrowse link
G KDM5A lysine demethylase 5A multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of KDM5A mRNA CTD PMID:27424125 NCBI chr12:280,057...389,320
Ensembl chr12:280,057...389,320 		JBrowse link
G KITLG KIT ligand multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of KITLG mRNA CTD PMID:27424125 NCBI chr12:88,492,793...88,580,471
Ensembl chr12:88,492,793...88,580,851 		JBrowse link
G KNSTRN kinetochore localized astrin (SPAG5) binding protein multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of KNSTRN mRNA CTD PMID:27424125 NCBI chr15:40,382,721...40,394,288
Ensembl chr15:40,382,721...40,394,288 		JBrowse link
G LDLRAP1 low density lipoprotein receptor adaptor protein 1 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of LDLRAP1 mRNA CTD PMID:27424125 NCBI chr 1:25,543,606...25,590,400
Ensembl chr 1:25,543,606...25,568,886 		JBrowse link
G LMOD1 leiomodin 1 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of LMOD1 mRNA CTD PMID:27424125 NCBI chr 1:201,896,456...201,946,548
Ensembl chr 1:201,896,456...201,946,548 		JBrowse link
G LRG1 leucine rich alpha-2-glycoprotein 1 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of LRG1 mRNA CTD PMID:27424125 NCBI chr19:4,536,402...4,540,036
Ensembl chr19:4,536,402...4,540,036 		JBrowse link
G LSR lipolysis stimulated lipoprotein receptor multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of LSR mRNA CTD PMID:27424125 NCBI chr19:35,249,002...35,267,964
Ensembl chr19:35,248,330...35,267,964 		JBrowse link
G MRPL33 mitochondrial ribosomal protein L33 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of MRPL33 mRNA CTD PMID:27424125 NCBI chr 2:27,771,719...27,779,733
Ensembl chr 2:27,771,717...27,988,087 		JBrowse link
G MTMR11 myotubularin related protein 11 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of MTMR11 mRNA CTD PMID:27424125 NCBI chr 1:149,928,651...149,936,879
Ensembl chr 1:149,928,651...149,936,879 		JBrowse link
G MYOF myoferlin multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of MYOF mRNA CTD PMID:27424125 NCBI chr10:93,306,429...93,482,334
Ensembl chr10:93,306,429...93,482,334 		JBrowse link
G NR4A1 nuclear receptor subfamily 4 group A member 1 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of NR4A1 mRNA CTD PMID:27424125 NCBI chr12:52,022,832...52,059,503
Ensembl chr12:52,022,832...52,059,507 		JBrowse link
G NR5A1 nuclear receptor subfamily 5 group A member 1 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of NR5A1 mRNA; [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of NR5A1 protein; [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in increased methylation of NR5A1 promoter; decitabine inhibits the reaction [[Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of NR5A1 mRNA] CTD PMID:28964809 NCBI chr 9:124,481,236...124,507,399
Ensembl chr 9:124,481,236...124,507,420 		JBrowse link
G PRKACA protein kinase cAMP-activated catalytic subunit alpha multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of PRKACA mRNA CTD PMID:27424125 NCBI chr19:14,091,688...14,117,762
Ensembl chr19:14,091,688...14,118,084 		JBrowse link
G PRPF40A pre-mRNA processing factor 40 homolog A multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of PRPF40A mRNA CTD PMID:27424125 NCBI chr 2:152,651,732...152,718,019
Ensembl chr 2:152,651,593...152,718,012 		JBrowse link
G PSPC1 paraspeckle component 1 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of PSPC1 mRNA CTD PMID:27424125 NCBI chr13:19,671,205...19,782,945
Ensembl chr13:19,674,752...19,783,019 		JBrowse link
G PTH1R parathyroid hormone 1 receptor multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of PTH1R mRNA CTD PMID:27424125 NCBI chr 3:46,877,721...46,903,799
Ensembl chr 3:46,877,721...46,903,799 		JBrowse link
G RASSF5 Ras association domain family member 5 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of RASSF5 mRNA CTD PMID:27424125 NCBI chr 1:206,507,531...206,589,448
Ensembl chr 1:206,507,531...206,589,448 		JBrowse link
G RGS22 regulator of G protein signaling 22 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of RGS22 mRNA CTD PMID:27424125 NCBI chr 8:99,960,936...100,106,049
Ensembl chr 8:99,960,936...100,131,268 		JBrowse link
G S1PR3 sphingosine-1-phosphate receptor 3 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of S1PR3 mRNA CTD PMID:27424125 NCBI chr 9:88,990,863...89,005,155
Ensembl chr 9:88,990,863...89,005,155 		JBrowse link
G SELPLG selectin P ligand multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of SELPLG mRNA CTD PMID:27424125 NCBI chr12:108,621,895...108,633,894
Ensembl chr12:108,621,895...108,633,894 		JBrowse link
G SIGLEC10 sialic acid binding Ig like lectin 10 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of SIGLEC10 mRNA CTD PMID:27424125 NCBI chr19:51,410,020...51,417,642
Ensembl chr19:51,410,020...51,417,803 		JBrowse link
G SLC16A1 solute carrier family 16 member 1 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of SLC16A1 mRNA CTD PMID:27424125 NCBI chr 1:112,911,847...112,956,196
Ensembl chr 1:112,911,847...112,957,593 		JBrowse link
G SNX30 sorting nexin family member 30 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of SNX30 mRNA CTD PMID:27424125 NCBI chr 9:112,749,723...112,885,769
Ensembl chr 9:112,750,760...112,881,671 		JBrowse link
G SSC5D scavenger receptor cysteine rich family member with 5 domains multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of SSC5D mRNA CTD PMID:27424125 NCBI chr19:55,488,436...55,519,099
Ensembl chr19:55,488,404...55,519,099 		JBrowse link
G STAR steroidogenic acute regulatory protein multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of STAR mRNA; [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of STAR protein CTD PMID:28964809 NCBI chr 8:38,142,700...38,150,952
Ensembl chr 8:38,142,700...38,150,992 		JBrowse link
G STYXL1 serine/threonine/tyrosine interacting like 1 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of STYXL1 mRNA CTD PMID:27424125 NCBI chr 7:75,996,337...76,048,000
Ensembl chr 7:75,996,338...76,048,004 		JBrowse link
G SUMO1 small ubiquitin like modifier 1 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of SUMO1 mRNA CTD PMID:27424125 NCBI chr 2:202,206,171...202,238,597
Ensembl chr 2:202,206,182...202,238,599 		JBrowse link
G TC2N tandem C2 domains, nuclear multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of TC2N mRNA CTD PMID:27424125 NCBI chr14:91,779,746...91,867,536
Ensembl chr14:91,779,746...91,867,536 		JBrowse link
G TP53I11 tumor protein p53 inducible protein 11 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of TP53I11 mRNA CTD PMID:27424125 NCBI chr11:44,932,348...44,951,306
Ensembl chr11:44,885,903...44,951,306 		JBrowse link
G VCPIP1 valosin containing protein interacting protein 1 multiple interactions EXP [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of VCPIP1 mRNA CTD PMID:27424125 NCBI chr 8:66,628,487...66,667,231
Ensembl chr 8:66,628,487...66,667,231 		JBrowse link
gypenoside LXXV term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKT1 AKT serine/threonine kinase 1 multiple interactions
increases phosphorylation		 ISO 2-chloro-5-nitrobenzanilide inhibits the reaction [gypenoside LXXV results in increased phosphorylation of AKT1 protein] CTD PMID:35192202 PMID:36325883 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,759 		JBrowse link
G CCL2 C-C motif chemokine ligand 2 multiple interactions ISO gypenoside LXXV inhibits the reaction [LEPR gene mutant form results in increased expression of CCL2 protein] CTD PMID:35192202 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208 		JBrowse link
G CCN2 cellular communication network factor 2 increases expression
multiple interactions		 ISO gypenoside LXXV results in increased expression of CTGF mRNA
gypenoside LXXV results in increased expression of and results in increased secretion of CTGF protein		 CTD PMID:31018484 NCBI chr 6:131,948,176...131,951,372
Ensembl chr 6:131,948,176...131,951,372 		JBrowse link
G IL1B interleukin 1 beta multiple interactions ISO gypenoside LXXV inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of IL1B protein]; gypenoside LXXV inhibits the reaction [LEPR gene mutant form results in increased expression of IL1B protein] CTD PMID:33050067 PMID:35192202 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL6 interleukin 6 multiple interactions ISO gypenoside LXXV inhibits the reaction [LEPR gene mutant form results in increased expression of IL6 protein] CTD PMID:35192202 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G IRS1 insulin receptor substrate 1 decreases phosphorylation
multiple interactions		 ISO gypenoside LXXV results in decreased phosphorylation of IRS1 protein
2-chloro-5-nitrobenzanilide inhibits the reaction [gypenoside LXXV results in decreased expression of and results in decreased phosphorylation of IRS1 protein]; gypenoside LXXV results in decreased expression of and results in decreased phosphorylation of IRS1 protein		 CTD PMID:35192202 PMID:36325883 NCBI chr 2:226,731,312...226,799,820
Ensembl chr 2:226,731,312...226,799,820 		JBrowse link
G LEPR leptin receptor multiple interactions ISO gypenoside LXXV inhibits the reaction [LEPR gene mutant form results in increased expression of CCL2 protein]; gypenoside LXXV inhibits the reaction [LEPR gene mutant form results in increased expression of IL1B protein]; gypenoside LXXV inhibits the reaction [LEPR gene mutant form results in increased expression of IL6 protein]; gypenoside LXXV inhibits the reaction [LEPR gene mutant form results in increased expression of TNF protein] CTD PMID:35192202 NCBI chr 1:65,420,652...65,641,559
Ensembl chr 1:65,420,652...65,641,559 		JBrowse link
G NR3C2 nuclear receptor subfamily 3 group C member 2 multiple interactions ISO gypenoside LXXV binds to and affects the localization of NR3C2 protein CTD PMID:31018484 NCBI chr 4:148,078,764...148,445,508
Ensembl chr 4:148,078,762...148,444,698 		JBrowse link
G PPARG peroxisome proliferator activated receptor gamma increases expression
multiple interactions		 ISO gypenoside LXXV results in increased expression of PPARG protein
2-chloro-5-nitrobenzanilide inhibits the reaction [gypenoside LXXV results in increased expression of PPARG protein]
2-chloro-5-nitrobenzanilide inhibits the reaction [gypenoside LXXV binds to and results in increased activity of PPARG protein]; gypenoside LXXV binds to and results in increased activity of PPARG protein		 CTD PMID:35192202 PMID:36325883 NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit multiple interactions ISO gypenoside LXXV results in decreased expression of and results in decreased phosphorylation of RELA protein CTD PMID:33050067 NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090 		JBrowse link
G SLC2A4 solute carrier family 2 member 4 multiple interactions
affects localization
increases expression		 ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [gypenoside LXXV affects the localization of SLC2A4 protein]; 2-chloro-5-nitrobenzanilide inhibits the reaction [gypenoside LXXV affects the localization of SLC2A4 protein]; 2-chloro-5-nitrobenzanilide inhibits the reaction [gypenoside LXXV results in increased expression of SLC2A4 protein] CTD PMID:35192202 PMID:36325883 NCBI chr17:7,281,718...7,288,257
Ensembl chr17:7,281,718...7,288,257 		JBrowse link
G TGFB1 transforming growth factor beta 1 decreases expression ISO gypenoside LXXV results in decreased expression of TGFB1 protein CTD PMID:33050067 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922 		JBrowse link
G TNF tumor necrosis factor multiple interactions ISO gypenoside LXXV inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of TNF protein]; gypenoside LXXV inhibits the reaction [LEPR gene mutant form results in increased expression of TNF protein]; gypenoside LXXV inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA] CTD PMID:33050067 PMID:35192202 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
hydroquinone O-beta-D-glucopyranoside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA10 ATP binding cassette subfamily A member 10 decreases expression EXP Arbutin results in decreased expression of ABCA10 mRNA CTD PMID:17103032 NCBI chr17:69,148,007...69,244,848
Ensembl chr17:69,147,214...69,244,846 		JBrowse link
G ABCA13 ATP binding cassette subfamily A member 13 decreases expression EXP Arbutin results in decreased expression of ABCA13 mRNA CTD PMID:17103032 NCBI chr 7:48,171,458...48,647,497
Ensembl chr 7:48,171,458...48,647,497 		JBrowse link
G ABCC13 ATP binding cassette subfamily C member 13 (pseudogene) decreases expression EXP Arbutin results in decreased expression of ABCC13 mRNA CTD PMID:17103032 NCBI chr21:14,273,799...14,301,386
Ensembl chr21:14,236,206...14,338,017
Ensembl chr21:14,236,206...14,338,017 		JBrowse link
G ACMSD aminocarboxymuconate semialdehyde decarboxylase decreases expression EXP Arbutin results in decreased expression of ACMSD mRNA CTD PMID:17103032 NCBI chr 2:134,838,616...134,902,034
Ensembl chr 2:134,838,616...134,902,034 		JBrowse link
G ACVRL1 activin A receptor like type 1 decreases expression EXP Arbutin results in decreased expression of ACVRL1 mRNA CTD PMID:17103032 NCBI chr12:51,906,944...51,923,361
Ensembl chr12:51,906,908...51,923,361 		JBrowse link
G ADAM19 ADAM metallopeptidase domain 19 decreases expression EXP Arbutin results in decreased expression of ADAM19 mRNA CTD PMID:17103032 NCBI chr 5:157,477,304...157,575,775
Ensembl chr 5:157,395,534...157,575,775 		JBrowse link
G ADAM20 ADAM metallopeptidase domain 20 decreases expression EXP Arbutin results in decreased expression of ADAM20 mRNA CTD PMID:17103032 NCBI chr14:70,522,358...70,579,452
Ensembl chr14:70,522,358...70,535,015 		JBrowse link
G ADAM7 ADAM metallopeptidase domain 7 increases expression EXP Arbutin results in increased expression of ADAM7 mRNA CTD PMID:17103032 NCBI chr 8:24,441,026...24,509,565
Ensembl chr 8:24,440,930...24,526,970 		JBrowse link
G ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif 3 decreases expression EXP Arbutin results in decreased expression of ADAMTS3 mRNA CTD PMID:17103032 NCBI chr 4:72,280,969...72,569,221
Ensembl chr 4:72,280,969...72,569,221 		JBrowse link
G ADAMTS9 ADAM metallopeptidase with thrombospondin type 1 motif 9 decreases expression EXP Arbutin results in decreased expression of ADAMTS9 mRNA CTD PMID:17103032 NCBI chr 3:64,515,654...64,688,000
Ensembl chr 3:64,515,654...64,688,000 		JBrowse link
G ADRB3 adrenoceptor beta 3 decreases expression EXP Arbutin results in decreased expression of ADRB3 mRNA CTD PMID:17103032 NCBI chr 8:37,962,990...37,966,599
Ensembl chr 8:37,962,990...37,966,599 		JBrowse link
G AEBP2 AE binding protein 2 increases expression EXP Arbutin results in increased expression of AEBP2 mRNA CTD PMID:17103032 NCBI chr12:19,404,072...19,522,227
Ensembl chr12:19,404,045...19,720,801 		JBrowse link
G AFAP1 actin filament associated protein 1 decreases expression EXP Arbutin results in decreased expression of AFAP1 mRNA CTD PMID:17103032 NCBI chr 4:7,758,713...7,939,861
Ensembl chr 4:7,758,714...7,939,926 		JBrowse link
G AGBL4 AGBL carboxypeptidase 4 decreases expression EXP Arbutin results in decreased expression of AGBL4 mRNA CTD PMID:17103032 NCBI chr 1:48,522,511...50,023,954
Ensembl chr 1:48,532,854...50,023,954 		JBrowse link
G AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3 decreases expression EXP Arbutin results in decreased expression of AGPAT3 mRNA CTD PMID:17103032 NCBI chr21:43,865,223...43,987,592
Ensembl chr21:43,865,223...43,987,592 		JBrowse link
G AHNAK AHNAK nucleoprotein decreases expression EXP Arbutin results in decreased expression of AHNAK mRNA CTD PMID:17103032 NCBI chr11:62,433,544...62,546,806
Ensembl chr11:62,433,542...62,556,235 		JBrowse link
G AKT1 AKT serine/threonine kinase 1 decreases expression EXP Arbutin results in decreased expression of AKT1 mRNA CTD PMID:17103032 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,759 		JBrowse link
G ALB albumin multiple interactions EXP ALB protein binds to and affects the transport of Arbutin CTD PMID:8831264 NCBI chr 4:73,404,287...73,421,482
Ensembl chr 4:73,397,114...73,421,482 		JBrowse link
G AMTN amelotin decreases expression EXP Arbutin results in decreased expression of AMTN mRNA CTD PMID:17103032 NCBI chr 4:70,518,569...70,532,743
Ensembl chr 4:70,518,569...70,532,743 		JBrowse link
G ANKRD17 ankyrin repeat domain 17 increases expression EXP Arbutin results in increased expression of ANKRD17 mRNA CTD PMID:17103032 NCBI chr 4:73,073,376...73,258,798
Ensembl chr 4:73,073,376...73,258,798 		JBrowse link
G ANKRD23 ankyrin repeat domain 23 increases expression EXP Arbutin results in increased expression of ANKRD23 mRNA CTD PMID:17103032 NCBI chr 2:96,837,912...96,844,021
Ensembl chr 2:96,824,526...96,857,934 		JBrowse link
G AP1S1 adaptor related protein complex 1 subunit sigma 1 decreases expression EXP Arbutin results in decreased expression of AP1S1 mRNA CTD PMID:17103032 NCBI chr 7:101,154,476...101,161,276
Ensembl chr 7:101,154,456...101,161,596 		JBrowse link
G APOM apolipoprotein M increases expression EXP Arbutin results in increased expression of APOM mRNA CTD PMID:17103032 NCBI chr 6:31,652,404...31,658,210
Ensembl chr 6:31,652,416...31,658,210 		JBrowse link
G APTX aprataxin decreases expression EXP Arbutin results in decreased expression of APTX mRNA CTD PMID:17103032 NCBI chr 9:32,972,616...33,025,120
Ensembl chr 9:32,886,601...33,025,130 		JBrowse link
G ARFIP2 ADP ribosylation factor interacting protein 2 decreases expression EXP Arbutin results in decreased expression of ARFIP2 mRNA CTD PMID:17103032 NCBI chr11:6,476,519...6,481,331
Ensembl chr11:6,474,683...6,481,479 		JBrowse link
G ARHGEF2 Rho/Rac guanine nucleotide exchange factor 2 decreases expression EXP Arbutin results in decreased expression of ARHGEF2 mRNA CTD PMID:17103032 NCBI chr 1:155,946,854...155,979,617
Ensembl chr 1:155,946,851...156,007,070 		JBrowse link
G ARL2 ADP ribosylation factor like GTPase 2 decreases expression EXP Arbutin results in decreased expression of ARL2 mRNA CTD PMID:17103032 NCBI chr11:65,014,160...65,022,184
Ensembl chr11:65,014,160...65,022,184 		JBrowse link
G ARL6IP1 ADP ribosylation factor like GTPase 6 interacting protein 1 increases expression EXP Arbutin results in increased expression of ARL6IP1 mRNA CTD PMID:17103032 NCBI chr16:18,791,667...18,801,549
Ensembl chr16:18,791,669...18,801,572 		JBrowse link
G ARX aristaless related homeobox decreases expression EXP Arbutin results in decreased expression of ARX mRNA CTD PMID:17103032 NCBI chr  X:25,003,694...25,015,965
Ensembl chr  X:25,003,694...25,016,420 		JBrowse link
G ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 increases expression EXP Arbutin results in increased expression of ASAP1 mRNA CTD PMID:17103032 NCBI chr 8:130,052,104...130,443,674
Ensembl chr 8:130,052,104...130,443,674 		JBrowse link
G ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 decreases expression EXP Arbutin results in decreased expression of ASAP3 mRNA CTD PMID:17103032 NCBI chr 1:23,428,563...23,484,631
Ensembl chr 1:23,428,563...23,484,637 		JBrowse link
G ATAD3B ATPase family AAA domain containing 3B decreases expression EXP Arbutin results in decreased expression of ATAD3B mRNA CTD PMID:17103032 NCBI chr 1:1,471,765...1,509,466
Ensembl chr 1:1,471,765...1,497,848 		JBrowse link
G ATF6B activating transcription factor 6 beta decreases expression EXP Arbutin results in decreased expression of ATF6B mRNA CTD PMID:17103032 NCBI chr 6:32,115,264...32,128,246
Ensembl chr 6:32,115,264...32,128,253 		JBrowse link
G B4GALNT4 beta-1,4-N-acetyl-galactosaminyltransferase 4 decreases expression EXP Arbutin results in decreased expression of B4GALNT4 mRNA CTD PMID:17103032 NCBI chr11:369,499...382,117
Ensembl chr11:369,499...382,117 		JBrowse link
G BAG5 BAG cochaperone 5 decreases expression EXP Arbutin results in decreased expression of BAG5 mRNA CTD PMID:17103032 NCBI chr14:103,556,551...103,562,657
Ensembl chr14:103,556,545...103,562,657 		JBrowse link
G BCAS2 BCAS2 pre-mRNA processing factor increases expression EXP Arbutin results in increased expression of BCAS2 mRNA CTD PMID:17103032 NCBI chr 1:114,567,557...114,581,615
Ensembl chr 1:114,567,557...114,581,629 		JBrowse link
G BCKDK branched chain keto acid dehydrogenase kinase decreases expression EXP Arbutin results in decreased expression of BCKDK mRNA CTD PMID:17103032 NCBI chr16:31,108,386...31,117,640
Ensembl chr16:31,106,107...31,112,791 		JBrowse link
G BMPR1B bone morphogenetic protein receptor type 1B decreases expression EXP Arbutin results in decreased expression of BMPR1B mRNA CTD PMID:17103032 NCBI chr 4:94,757,955...95,158,450
Ensembl chr 4:94,757,955...95,158,448 		JBrowse link
G BNIP2 BCL2 interacting protein 2 increases expression EXP Arbutin results in increased expression of BNIP2 mRNA CTD PMID:17103032 NCBI chr15:59,659,146...59,689,320
Ensembl chr15:59,659,146...59,689,339 		JBrowse link
G BRSK1 BR serine/threonine kinase 1 decreases expression EXP Arbutin results in decreased expression of BRSK1 mRNA CTD PMID:17103032 NCBI chr19:55,283,997...55,312,562
Ensembl chr19:55,282,072...55,312,562 		JBrowse link
G BST2 bone marrow stromal cell antigen 2 decreases expression EXP Arbutin results in decreased expression of BST2 mRNA CTD PMID:17103032 NCBI chr19:17,402,939...17,405,630
Ensembl chr19:17,402,939...17,405,630 		JBrowse link
G BTN2A1 butyrophilin subfamily 2 member A1 decreases expression EXP Arbutin results in decreased expression of BTN2A1 mRNA CTD PMID:17103032 NCBI chr 6:26,457,955...26,476,622
Ensembl chr 6:26,457,904...26,476,621 		JBrowse link
G C19orf33 chromosome 19 open reading frame 33 decreases expression EXP Arbutin results in decreased expression of C19ORF33 mRNA CTD PMID:17103032 NCBI chr19:38,304,251...38,305,006
Ensembl chr19:38,304,164...38,305,006 		JBrowse link
G C1orf87 chromosome 1 open reading frame 87 decreases expression EXP Arbutin results in decreased expression of C1ORF87 mRNA CTD PMID:17103032 NCBI chr 1:59,990,394...60,073,770
Ensembl chr 1:59,987,269...60,073,770 		JBrowse link
G C1QB complement C1q B chain decreases expression EXP Arbutin results in decreased expression of C1QB mRNA CTD PMID:17103032 NCBI chr 1:22,653,236...22,661,637
Ensembl chr 1:22,652,762...22,661,637 		JBrowse link
G CACNG7 calcium voltage-gated channel auxiliary subunit gamma 7 decreases expression EXP Arbutin results in decreased expression of CACNG7 mRNA CTD PMID:17103032 NCBI chr19:53,909,278...53,943,950
Ensembl chr19:53,909,278...53,943,950 		JBrowse link
G CAPNS2 calpain small subunit 2 increases expression EXP Arbutin results in increased expression of CAPNS2 mRNA CTD PMID:17103032 NCBI chr16:55,566,684...55,567,687
Ensembl chr16:55,566,684...55,567,687 		JBrowse link
G CASP8 caspase 8 decreases expression EXP Arbutin results in decreased expression of CASP8 mRNA CTD PMID:17103032 NCBI chr 2:201,233,463...201,287,711
Ensembl chr 2:201,233,443...201,361,836 		JBrowse link
G CAT catalase multiple interactions ISO Arbutin inhibits the reaction [potassium bromate results in decreased activity of CAT protein] CTD PMID:36284482 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060 		JBrowse link
G CBX6 chromobox 6 decreases expression EXP Arbutin results in decreased expression of CBX6 mRNA CTD PMID:17103032 NCBI chr22:38,861,422...38,872,216
Ensembl chr22:38,861,422...38,872,249 		JBrowse link
G CCAR1 cell division cycle and apoptosis regulator 1 increases expression EXP Arbutin results in increased expression of CCAR1 mRNA CTD PMID:17103032 NCBI chr10:68,721,239...68,792,377
Ensembl chr10:68,721,012...68,792,377 		JBrowse link
G CCDC170 coiled-coil domain containing 170 decreases expression EXP Arbutin results in decreased expression of CCDC170 mRNA CTD PMID:17103032 NCBI chr 6:151,494,017...151,621,193
Ensembl chr 6:151,494,017...151,621,193 		JBrowse link
G CCDC28B coiled-coil domain containing 28B decreases expression EXP Arbutin results in decreased expression of CCDC28B mRNA CTD PMID:17103032 NCBI chr 1:32,196,011...32,205,387
Ensembl chr 1:32,200,595...32,205,453 		JBrowse link
G CCNYL1 cyclin Y like 1 increases expression EXP Arbutin results in increased expression of CCNYL1 mRNA CTD PMID:17103032 NCBI chr 2:207,711,640...207,756,174
Ensembl chr 2:207,711,540...207,761,839 		JBrowse link
G CCT8 chaperonin containing TCP1 subunit 8 increases expression EXP Arbutin results in increased expression of CCT8 mRNA CTD PMID:17103032 NCBI chr21:29,056,326...29,073,648
Ensembl chr21:29,055,805...29,073,797 		JBrowse link
G CD151 CD151 molecule (Raph blood group) decreases expression EXP Arbutin results in decreased expression of CD151 mRNA CTD PMID:17103032 NCBI chr11:832,952...838,831
Ensembl chr11:832,887...839,831 		JBrowse link
G CD160 CD160 molecule decreases expression EXP Arbutin results in decreased expression of CD160 mRNA CTD PMID:17103032 NCBI chr 1:145,719,499...145,739,288
Ensembl chr 1:145,719,471...145,739,288 		JBrowse link
G CD163L1 CD163 molecule like 1 decreases expression EXP Arbutin results in decreased expression of CD163L1 mRNA CTD PMID:17103032 NCBI chr12:7,318,768...7,444,153
Ensembl chr12:7,346,685...7,479,897 		JBrowse link
G CD2BP2 CD2 cytoplasmic tail binding protein 2 decreases expression EXP Arbutin results in decreased expression of CD2BP2 mRNA CTD PMID:17103032 NCBI chr16:30,350,773...30,355,308
Ensembl chr16:30,350,773...30,355,308 		JBrowse link
G CD3G CD3 gamma subunit of T-cell receptor complex decreases expression EXP Arbutin results in decreased expression of CD3G mRNA CTD PMID:17103032 NCBI chr11:118,344,344...118,355,161
Ensembl chr11:118,344,344...118,355,161 		JBrowse link
G CDIN1 CDAN1 interacting nuclease 1 increases expression EXP Arbutin results in increased expression of CDIN1 mRNA CTD PMID:17103032 NCBI chr15:36,579,626...36,810,244
Ensembl chr15:36,579,626...36,810,248 		JBrowse link
G CDK16 cyclin dependent kinase 16 decreases expression EXP Arbutin results in decreased expression of CDK16 mRNA CTD PMID:17103032 NCBI chr  X:47,218,303...47,229,997
Ensembl chr  X:47,217,860...47,229,997 		JBrowse link
G CEACAM1 CEA cell adhesion molecule 1 decreases expression EXP Arbutin results in decreased expression of CEACAM1 mRNA CTD PMID:17103032 NCBI chr19:42,507,306...42,528,481
Ensembl chr19:42,507,304...42,561,234 		JBrowse link
G CFAP161 cilia and flagella associated protein 161 decreases expression EXP Arbutin results in decreased expression of CFAP161 mRNA CTD PMID:17103032 NCBI chr15:81,099,408...81,149,179
Ensembl chr15:81,007,033...81,149,179 		JBrowse link
G CFAP70 cilia and flagella associated protein 70 decreases expression EXP Arbutin results in decreased expression of CFAP70 mRNA CTD PMID:17103032 NCBI chr10:73,253,762...73,362,979
Ensembl chr10:73,253,762...73,358,864 		JBrowse link
G CLEC4C C-type lectin domain family 4 member C decreases expression EXP Arbutin results in decreased expression of CLEC4C mRNA CTD PMID:17103032 NCBI chr12:7,729,383...7,749,541
Ensembl chr12:7,729,383...7,751,605 		JBrowse link
G CNKSR2 connector enhancer of kinase suppressor of Ras 2 decreases expression EXP Arbutin results in decreased expression of CNKSR2 mRNA CTD PMID:17103032 NCBI chr  X:21,374,418...21,654,689
Ensembl chr  X:21,372,801...21,654,695 		JBrowse link
G COL17A1 collagen type XVII alpha 1 chain decreases expression EXP Arbutin results in decreased expression of COL17A1 mRNA CTD PMID:17103032 NCBI chr10:104,031,286...104,085,880
Ensembl chr10:104,031,286...104,085,880 		JBrowse link
G CPB1 carboxypeptidase B1 decreases expression EXP Arbutin results in decreased expression of CPB1 mRNA CTD PMID:17103032 NCBI chr 3:148,827,811...148,860,187
Ensembl chr 3:148,791,102...148,860,187 		JBrowse link
G CPE carboxypeptidase E increases expression EXP Arbutin results in increased expression of CPE mRNA CTD PMID:17103032 NCBI chr 4:165,379,008...165,498,547
Ensembl chr 4:165,361,194...165,498,547 		JBrowse link
G CPNE5 copine 5 increases expression EXP Arbutin results in increased expression of CPNE5 mRNA CTD PMID:17103032 NCBI chr 6:36,740,775...36,839,998
Ensembl chr 6:36,740,775...36,839,444 		JBrowse link
G CYP17A1 cytochrome P450 family 17 subfamily A member 1 decreases expression ISO Arbutin results in decreased expression of CYP17A1 mRNA; Arbutin results in decreased expression of CYP17A1 protein CTD PMID:37783241 NCBI chr10:102,830,531...102,837,413
Ensembl chr10:102,830,531...102,837,472 		JBrowse link
G CYP2U1 cytochrome P450 family 2 subfamily U member 1 increases expression EXP Arbutin results in increased expression of CYP2U1 mRNA CTD PMID:17103032 NCBI chr 4:107,931,549...107,953,461
Ensembl chr 4:107,931,549...107,953,461 		JBrowse link
G CYRIB CYFIP related Rac1 interactor B increases expression EXP Arbutin results in increased expression of CYRIB mRNA CTD PMID:17103032 NCBI chr 8:129,839,593...130,017,129
Ensembl chr 8:129,839,593...130,017,504 		JBrowse link
G DDX46 DEAD-box helicase 46 increases expression EXP Arbutin results in increased expression of DDX46 mRNA CTD PMID:17103032 NCBI chr 5:134,758,779...134,831,121
Ensembl chr 5:134,758,771...134,855,133 		JBrowse link
G DIAPH2 diaphanous related formin 2 decreases expression EXP Arbutin results in decreased expression of DIAPH2 mRNA CTD PMID:17103032 NCBI chr  X:96,684,842...97,604,997
Ensembl chr  X:96,684,712...97,604,997 		JBrowse link
G DLGAP4 DLG associated protein 4 increases expression EXP Arbutin results in increased expression of DLGAP4 mRNA CTD PMID:17103032 NCBI chr20:36,306,339...36,528,633
Ensembl chr20:36,306,336...36,528,637 		JBrowse link
G DLX1 distal-less homeobox 1 decreases expression EXP Arbutin results in decreased expression of DLX1 mRNA CTD PMID:17103032 NCBI chr 2:172,085,507...172,089,674
Ensembl chr 2:172,084,740...172,089,677 		JBrowse link
G DMXL1 Dmx like 1 decreases expression EXP Arbutin results in decreased expression of DMXL1 mRNA CTD PMID:17103032 NCBI chr 5:119,071,027...119,249,127
Ensembl chr 5:119,037,772...119,249,138 		JBrowse link
G DNAH7 dynein axonemal heavy chain 7 decreases expression EXP Arbutin results in decreased expression of DNAH7 mRNA CTD PMID:17103032 NCBI chr 2:195,737,703...196,068,837
Ensembl chr 2:195,737,703...196,068,837 		JBrowse link
G DNAI3 dynein axonemal intermediate chain 3 decreases expression EXP Arbutin results in decreased expression of DNAI3 mRNA CTD PMID:17103032 NCBI chr 1:85,062,327...85,133,138
Ensembl chr 1:84,999,147...85,133,138 		JBrowse link
G DNAJB9 DnaJ heat shock protein family (Hsp40) member B9 increases expression EXP Arbutin results in increased expression of DNAJB9 mRNA CTD PMID:17103032 NCBI chr 7:108,569,874...108,574,850
Ensembl chr 7:108,569,867...108,574,850 		JBrowse link
G DPP7 dipeptidyl peptidase 7 decreases expression EXP Arbutin results in decreased expression of DPP7 mRNA CTD PMID:17103032 NCBI chr 9:137,110,546...137,118,306
Ensembl chr 9:137,110,542...137,118,309 		JBrowse link
G DPYSL2 dihydropyrimidinase like 2 decreases expression EXP Arbutin results in decreased expression of DPYSL2 mRNA CTD PMID:17103032 NCBI chr 8:26,514,031...26,658,175
Ensembl chr 8:26,514,031...26,658,178 		JBrowse link
G ECE1 endothelin converting enzyme 1 increases expression EXP Arbutin results in increased expression of ECE1 mRNA CTD PMID:17103032 NCBI chr 1:21,217,250...21,345,504
Ensembl chr 1:21,217,247...21,345,572 		JBrowse link
G EEPD1 endonuclease/exonuclease/phosphatase family domain containing 1 increases expression EXP Arbutin results in increased expression of EEPD1 mRNA CTD PMID:17103032 NCBI chr 7:36,153,254...36,301,538
Ensembl chr 7:36,153,254...36,301,538 		JBrowse link
G EFHC2 EF-hand domain containing 2 decreases expression EXP Arbutin results in decreased expression of EFHC2 mRNA CTD PMID:17103032 NCBI chr  X:44,147,872...44,343,672
Ensembl chr  X:44,147,872...44,343,672 		JBrowse link
G EFL1 elongation factor like GTPase 1 increases expression EXP Arbutin results in increased expression of EFL1 mRNA CTD PMID:17103032 NCBI chr15:82,130,233...82,262,734
Ensembl chr15:82,130,206...82,262,773 		JBrowse link
G EFNA3 ephrin A3 decreases expression EXP Arbutin results in decreased expression of EFNA3 mRNA CTD PMID:17103032 NCBI chr 1:155,078,837...155,087,538
Ensembl chr 1:155,078,837...155,087,538 		JBrowse link
G EFS embryonal Fyn-associated substrate decreases expression EXP Arbutin results in decreased expression of EFS mRNA CTD PMID:17103032 NCBI chr14:23,356,406...23,365,172
Ensembl chr14:23,356,403...23,365,752 		JBrowse link
G EID1 EP300 interacting inhibitor of differentiation 1 increases expression EXP Arbutin results in increased expression of EID1 mRNA CTD PMID:17103032 NCBI chr15:48,878,134...48,880,173
Ensembl chr15:48,878,134...48,880,173 		JBrowse link
G ELANE elastase, neutrophil expressed decreases expression EXP Arbutin results in decreased expression of ELANE mRNA CTD PMID:17103032 NCBI chr19:852,303...856,243
Ensembl chr19:851,014...856,247 		JBrowse link
G EMX2 empty spiracles homeobox 2 decreases expression EXP Arbutin results in decreased expression of EMX2 mRNA CTD PMID:17103032 NCBI chr10:117,542,746...117,549,546
Ensembl chr10:117,542,445...117,549,546 		JBrowse link
G ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 decreases expression EXP Arbutin results in decreased expression of ENPP1 mRNA CTD PMID:17103032 NCBI chr 6:131,808,020...131,895,155
Ensembl chr 6:131,808,016...131,895,155 		JBrowse link
G EPS8 EGFR pathway substrate 8, signaling adaptor increases expression EXP Arbutin results in increased expression of EPS8 mRNA CTD PMID:17103032 NCBI chr12:15,620,134...15,789,388
Ensembl chr12:15,620,134...15,882,329 		JBrowse link
G EPX eosinophil peroxidase increases expression EXP Arbutin results in increased expression of EPX mRNA CTD PMID:17103032 NCBI chr17:58,192,726...58,205,174
Ensembl chr17:58,192,726...58,205,174 		JBrowse link
G ERC1 ELKS/RAB6-interacting/CAST family member 1 increases expression EXP Arbutin results in increased expression of ERC1 mRNA CTD PMID:17103032 NCBI chr12:989,959...1,495,933
Ensembl chr12:990,509...1,495,933 		JBrowse link
G ERC2-IT1 ERC2 intronic transcript 1 decreases expression EXP Arbutin results in decreased expression of ERC2-IT1 mRNA CTD PMID:17103032 NCBI chr 3:55,657,206...55,659,469
Ensembl chr 3:55,657,206...55,659,382 		JBrowse link
G ESR2 estrogen receptor 2 increases expression EXP
ISO		 Arbutin results in increased expression of ESR2 protein CTD PMID:29360751 NCBI chr14:64,226,707...64,338,613
Ensembl chr14:64,084,232...64,338,112 		JBrowse link
G EVI2B ecotropic viral integration site 2B decreases expression EXP Arbutin results in decreased expression of EVI2B mRNA CTD PMID:17103032 NCBI chr17:31,303,770...31,314,054
Ensembl chr17:31,303,770...31,314,105 		JBrowse link
G EXD1 exonuclease 3'-5' domain containing 1 decreases expression EXP Arbutin results in decreased expression of EXD1 mRNA CTD PMID:17103032 NCBI chr15:41,182,728...41,230,757
Ensembl chr15:41,182,725...41,230,757 		JBrowse link
G F13B coagulation factor XIII B chain decreases expression EXP Arbutin results in decreased expression of F13B mRNA CTD PMID:17103032 NCBI chr 1:197,038,741...197,067,260
Ensembl chr 1:197,038,741...197,067,260 		JBrowse link
G FAM3D FAM3 metabolism regulating signaling molecule D decreases expression EXP Arbutin results in decreased expression of FAM3D mRNA CTD PMID:17103032 NCBI chr 3:58,633,946...58,666,774
Ensembl chr 3:58,633,946...58,666,834 		JBrowse link
G FANCD2OS FANCD2 opposite strand decreases expression EXP Arbutin results in decreased expression of FANCD2OS mRNA CTD PMID:17103032 NCBI chr 3:10,081,320...10,108,457
Ensembl chr 3:10,081,317...10,108,255 		JBrowse link
G FASLG Fas ligand decreases expression EXP Arbutin results in decreased expression of FASLG mRNA CTD PMID:17103032 NCBI chr 1:172,659,103...172,666,876
Ensembl chr 1:172,659,103...172,666,876 		JBrowse link
G FBXO11 F-box protein 11 increases expression EXP Arbutin results in increased expression of FBXO11 mRNA CTD PMID:17103032 NCBI chr 2:47,806,920...47,906,498
Ensembl chr 2:47,789,316...47,906,498 		JBrowse link
G FBXO16 F-box protein 16 increases expression EXP Arbutin results in increased expression of FBXO16 mRNA CTD PMID:17103032 NCBI chr 8:28,428,412...28,490,229
Ensembl chr 8:28,348,287...28,490,278 		JBrowse link
G FGF5 fibroblast growth factor 5 decreases expression EXP Arbutin results in decreased expression of FGF5 mRNA CTD PMID:17103032 NCBI chr 4:80,266,588...80,291,017
Ensembl chr 4:80,266,639...80,336,680 		JBrowse link
G FGFR3 fibroblast growth factor receptor 3 decreases expression EXP Arbutin results in decreased expression of FGFR3 mRNA CTD PMID:17103032 NCBI chr 4:1,793,293...1,808,867
Ensembl chr 4:1,793,293...1,808,872 		JBrowse link
G FMNL3 formin like 3 decreases expression EXP Arbutin results in decreased expression of FMNL3 mRNA CTD PMID:17103032 NCBI chr12:49,636,499...49,707,405
Ensembl chr12:49,636,499...49,708,165 		JBrowse link
G FPGT fucose-1-phosphate guanylyltransferase decreases expression EXP Arbutin results in decreased expression of FPGT mRNA CTD PMID:17103032 NCBI chr 1:74,198,242...74,208,702
Ensembl chr 1:74,198,238...74,234,086 		JBrowse link
G FRAS1 Fraser extracellular matrix complex subunit 1 decreases expression EXP Arbutin results in decreased expression of FRAS1 mRNA CTD PMID:17103032 NCBI chr 4:78,057,323...78,544,269
Ensembl chr 4:78,057,323...78,544,269 		JBrowse link
G FRMPD4 FERM and PDZ domain containing 4 decreases expression EXP Arbutin results in decreased expression of FRMPD4 mRNA CTD PMID:17103032 NCBI chr  X:11,822,439...12,724,523
Ensembl chr  X:11,822,423...12,724,523 		JBrowse link
G FSHB follicle stimulating hormone subunit beta increases expression ISO Arbutin results in increased expression of FSHB protein CTD PMID:29360751 NCBI chr11:30,231,014...30,235,194
Ensembl chr11:30,231,014...30,235,261 		JBrowse link
G GALC galactosylceramidase increases expression EXP Arbutin results in increased expression of GALC mRNA CTD PMID:17103032 NCBI chr14:87,933,014...87,993,667
Ensembl chr14:87,837,820...87,993,665 		JBrowse link
G GAREM1 GRB2 associated regulator of MAPK1 subtype 1 increases expression EXP Arbutin results in increased expression of GAREM1 mRNA CTD PMID:17103032 NCBI chr18:32,263,522...32,470,882
Ensembl chr18:32,124,877...32,470,882 		JBrowse link
G GET3 guided entry of tail-anchored proteins factor 3, ATPase decreases expression EXP Arbutin results in decreased expression of GET3 mRNA CTD PMID:17103032 NCBI chr19:12,737,106...12,748,323
Ensembl chr19:12,737,139...12,748,323 		JBrowse link
G GIPC1 GIPC PDZ domain containing family member 1 decreases expression EXP Arbutin results in decreased expression of GIPC1 mRNA CTD PMID:17103032 NCBI chr19:14,477,762...14,496,127
Ensembl chr19:14,477,760...14,496,149 		JBrowse link
G GLT8D2 glycosyltransferase 8 domain containing 2 decreases expression EXP Arbutin results in decreased expression of GLT8D2 mRNA CTD PMID:17103032 NCBI chr12:103,988,987...104,064,437
Ensembl chr12:103,988,987...104,064,183 		JBrowse link
G GMPR guanosine monophosphate reductase decreases expression EXP Arbutin results in decreased expression of GMPR mRNA CTD PMID:17103032 NCBI chr 6:16,238,587...16,295,549
Ensembl chr 6:16,238,587...16,295,549 		JBrowse link
G GNL2 G protein nucleolar 2 increases expression EXP Arbutin results in increased expression of GNL2 mRNA CTD PMID:17103032 NCBI chr 1:37,566,816...37,595,937
Ensembl chr 1:37,566,816...37,595,937 		JBrowse link
G GPC3 glypican 3 decreases expression EXP Arbutin results in decreased expression of GPC3 mRNA CTD PMID:17103032 NCBI chr  X:133,535,745...133,985,594
Ensembl chr  X:133,535,745...133,987,100 		JBrowse link
G GPD2 glycerol-3-phosphate dehydrogenase 2 increases expression EXP Arbutin results in increased expression of GPD2 mRNA CTD PMID:17103032 NCBI chr 2:156,400,281...156,586,403
Ensembl chr 2:156,435,290...156,613,735 		JBrowse link
G GPER1 G protein-coupled estrogen receptor 1 increases expression ISO
EXP		 Arbutin results in increased expression of GPER1 protein CTD PMID:29360751 NCBI chr 7:1,087,118...1,093,810
Ensembl chr 7:1,082,208...1,093,815 		JBrowse link
G GPR155 G protein-coupled receptor 155 decreases expression EXP Arbutin results in decreased expression of GPR155 mRNA CTD PMID:17103032 NCBI chr 2:174,431,571...174,487,029
Ensembl chr 2:174,431,571...174,487,094 		JBrowse link
G GPR26 G protein-coupled receptor 26 decreases expression EXP Arbutin results in decreased expression of GPR26 mRNA CTD PMID:17103032 NCBI chr10:123,666,355...123,697,399
Ensembl chr10:123,666,355...123,697,399 		JBrowse link
G GPR32 G protein-coupled receptor 32 increases expression EXP Arbutin results in increased expression of GPR32 mRNA CTD PMID:17103032 NCBI chr19:50,770,464...50,771,732
Ensembl chr19:50,770,464...50,771,732 		JBrowse link
G GPR55 G protein-coupled receptor 55 decreases expression EXP Arbutin results in decreased expression of GPR55 mRNA CTD PMID:17103032 NCBI chr 2:230,907,328...230,961,201
Ensembl chr 2:230,907,318...230,961,066 		JBrowse link
G GPRC5D G protein-coupled receptor class C group 5 member D decreases expression EXP Arbutin results in decreased expression of GPRC5D mRNA CTD PMID:17103032 NCBI chr12:12,940,575...12,952,170
Ensembl chr12:12,940,575...12,952,170 		JBrowse link
G GPT glutamic--pyruvic transaminase multiple interactions EXP
ISO		 Arbutin inhibits the reaction [Ethanol results in increased expression of GPT protein] CTD PMID:34346143 NCBI chr 8:144,503,068...144,507,172
Ensembl chr 8:144,502,973...144,507,174 		JBrowse link
G GSDMA gasdermin A decreases expression EXP Arbutin results in decreased expression of GSDMA mRNA CTD PMID:17103032 NCBI chr17:39,963,004...39,977,768
Ensembl chr17:39,953,263...39,977,768 		JBrowse link
G GUCY1A2 guanylate cyclase 1 soluble subunit alpha 2 decreases expression EXP Arbutin results in decreased expression of GUCY1A2 mRNA CTD PMID:17103032 NCBI chr11:106,674,019...107,018,476
Ensembl chr11:106,674,019...107,018,476 		JBrowse link
G H1-1 H1.1 linker histone, cluster member increases expression EXP Arbutin results in increased expression of H1-1 mRNA CTD PMID:17103032 NCBI chr 6:26,017,032...26,017,787
Ensembl chr 6:26,017,032...26,017,787 		JBrowse link
G H2AC6 H2A clustered histone 6 increases expression EXP Arbutin results in increased expression of H2AC6 mRNA CTD PMID:17103032 NCBI chr 6:26,124,172...26,124,690
Ensembl chr 6:26,124,145...26,139,116 		JBrowse link
G HAND1 heart and neural crest derivatives expressed 1 increases expression EXP Arbutin results in increased expression of HAND1 mRNA CTD PMID:17103032 NCBI chr 5:154,474,972...154,478,227
Ensembl chr 5:154,474,972...154,478,227 		JBrowse link
G HLF HLF transcription factor, PAR bZIP family member decreases expression EXP Arbutin results in decreased expression of HLF mRNA CTD PMID:17103032 NCBI chr17:55,264,960...55,325,187
Ensembl chr17:55,264,960...55,325,187 		JBrowse link
G HMOX1 heme oxygenase 1 multiple interactions ISO Arbutin inhibits the reaction [Ethanol results in decreased expression of HMOX1 mRNA] CTD PMID:34346143 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214 		JBrowse link
G HOXB8 homeobox B8 decreases expression EXP Arbutin results in decreased expression of HOXB8 mRNA CTD PMID:17103032 NCBI chr17:48,612,346...48,615,292
Ensembl chr17:48,611,377...48,615,292 		JBrowse link
G HPS3 HPS3 biogenesis of lysosomal organelles complex 2 subunit 1 decreases expression EXP Arbutin results in decreased expression of HPS3 mRNA CTD PMID:17103032 NCBI chr 3:149,129,638...149,173,732
Ensembl chr 3:149,129,638...149,173,732 		JBrowse link
G HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 decreases expression EXP
ISO		 Arbutin results in decreased expression of HSD3B1 mRNA
Arbutin results in decreased expression of HSD3B1 mRNA; Arbutin results in decreased expression of HSD3B1 protein		 CTD PMID:17103032 PMID:37783241 NCBI chr 1:119,507,203...119,515,058
Ensembl chr 1:119,507,198...119,515,054 		JBrowse link
G HTATSF1 HIV-1 Tat specific factor 1 increases expression EXP Arbutin results in increased expression of HTATSF1 mRNA CTD PMID:17103032 NCBI chr  X:136,497,229...136,512,346
Ensembl chr  X:136,497,079...136,512,346 		JBrowse link
G IFIT3 interferon induced protein with tetratricopeptide repeats 3 decreases expression EXP Arbutin results in decreased expression of IFIT3 mRNA CTD PMID:17103032 NCBI chr10:89,327,997...89,340,968
Ensembl chr10:89,327,307...89,377,473 		JBrowse link
G IGDCC3 immunoglobulin superfamily DCC subclass member 3 decreases expression EXP Arbutin results in decreased expression of IGDCC3 mRNA CTD PMID:17103032 NCBI chr15:65,327,127...65,378,002
Ensembl chr15:65,327,127...65,378,002 		JBrowse link
G IL23A interleukin 23 subunit alpha decreases expression EXP Arbutin results in decreased expression of IL23A mRNA CTD PMID:17103032 NCBI chr12:56,338,884...56,340,410
Ensembl chr12:56,334,174...56,340,410 		JBrowse link
G IL3RA interleukin 3 receptor subunit alpha increases expression EXP Arbutin results in increased expression of IL3RA mRNA CTD PMID:17103032 NCBI chr  X:1,336,785...1,382,689
NCBI chr  Y:1,336,785...1,382,689
Ensembl chr  Y:1,336,616...1,382,689
Ensembl chr  X:1,336,616...1,382,689 		JBrowse link
G IL6 interleukin 6 multiple interactions ISO Arbutin inhibits the reaction [Ethanol results in increased expression of IL6 protein] CTD PMID:34346143 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G IL6ST interleukin 6 cytokine family signal transducer decreases expression EXP Arbutin results in decreased expression of IL6ST mRNA CTD PMID:17103032 NCBI chr 5:55,935,095...55,994,963
Ensembl chr 5:55,935,095...55,995,022 		JBrowse link
G INA internexin neuronal intermediate filament protein alpha decreases expression EXP Arbutin results in decreased expression of INA mRNA CTD PMID:17103032 NCBI chr10:103,277,138...103,290,346
Ensembl chr10:103,277,138...103,290,346 		JBrowse link
G INPP4B inositol polyphosphate-4-phosphatase type II B increases expression EXP Arbutin results in increased expression of INPP4B mRNA CTD PMID:17103032 NCBI chr 4:142,023,160...142,846,535
Ensembl chr 4:142,023,160...142,847,432 		JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit decreases expression EXP Arbutin results in decreased expression of JUN mRNA CTD PMID:17103032 NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,776,845...58,784,048 		JBrowse link
G KCNAB3 potassium voltage-gated channel subfamily A regulatory beta subunit 3 decreases expression EXP Arbutin results in decreased expression of KCNAB3 mRNA CTD PMID:17103032 NCBI chr17:7,921,859...7,929,856
Ensembl chr17:7,921,859...7,929,856 		JBrowse link
G KCTD17 potassium channel tetramerization domain containing 17 decreases expression EXP Arbutin results in decreased expression of KCTD17 mRNA CTD PMID:17103032 NCBI chr22:37,051,742...37,063,390
Ensembl chr22:37,051,739...37,063,390 		JBrowse link
G KIF26B kinesin family member 26B decreases expression EXP Arbutin results in decreased expression of KIF26B mRNA CTD PMID:17103032 NCBI chr 1:245,154,985...245,709,432
Ensembl chr 1:245,154,985...245,709,432 		JBrowse link
G KLHL13 kelch like family member 13 increases expression EXP Arbutin results in increased expression of KLHL13 mRNA CTD PMID:17103032 NCBI chr  X:117,897,813...118,117,340
Ensembl chr  X:117,897,813...118,117,340 		JBrowse link
G KLRC4 killer cell lectin like receptor C4 increases expression EXP Arbutin results in increased expression of KLRC4 mRNA CTD PMID:17103032 NCBI chr12:10,407,384...10,409,757
Ensembl chr12:10,407,384...10,409,757 		JBrowse link
G LCTL lactase like decreases expression EXP Arbutin results in decreased expression of LCTL mRNA CTD PMID:17103032 NCBI chr15:66,547,532...66,565,998
Ensembl chr15:66,547,179...66,565,998 		JBrowse link
G LGALS14 galectin 14 decreases expression EXP Arbutin results in decreased expression of LGALS14 mRNA CTD PMID:17103032 NCBI chr19:39,704,481...39,709,444
Ensembl chr19:39,704,481...39,709,444 		JBrowse link
G LHCGR luteinizing hormone/choriogonadotropin receptor decreases expression ISO Arbutin results in decreased expression of LHCGR mRNA; Arbutin results in decreased expression of LHCGR protein CTD PMID:37783241 NCBI chr 2:48,686,774...48,755,724
Ensembl chr 2:48,686,774...48,755,730 		JBrowse link
G LILRP2 leukocyte immunoglobulin-like receptor pseudogene 2 decreases expression EXP Arbutin results in decreased expression of LILRP2 mRNA CTD PMID:17103032 NCBI chr19:54,707,916...54,713,452
Ensembl chr19:54,707,916...54,713,453
Ensembl chr19:54,707,916...54,713,453 		JBrowse link
G LRP5 LDL receptor related protein 5 decreases expression EXP Arbutin results in decreased expression of LRP5 mRNA CTD PMID:17103032 NCBI chr11:68,298,412...68,449,275
Ensembl chr11:68,312,591...68,449,275 		JBrowse link
G LRP6 LDL receptor related protein 6 decreases expression EXP Arbutin results in decreased expression of LRP6 mRNA CTD PMID:17103032 NCBI chr12:12,116,025...12,267,044
Ensembl chr12:12,116,025...12,267,044 		JBrowse link
G LRRC4 leucine rich repeat containing 4 decreases expression EXP Arbutin results in decreased expression of LRRC4 mRNA CTD PMID:17103032 NCBI chr 7:128,027,071...128,032,128
Ensembl chr 7:128,027,071...128,032,107 		JBrowse link
G LRRTM4 leucine rich repeat transmembrane neuronal 4 decreases expression EXP Arbutin results in decreased expression of LRRTM4 mRNA CTD PMID:17103032 NCBI chr 2:76,747,685...77,522,376
Ensembl chr 2:76,747,685...77,593,319 		JBrowse link
G MAFK MAF bZIP transcription factor K decreases expression EXP Arbutin results in decreased expression of MAFK mRNA CTD PMID:17103032 NCBI chr 7:1,530,702...1,543,043
Ensembl chr 7:1,530,702...1,543,043 		JBrowse link
G MAP4K5 mitogen-activated protein kinase kinase kinase kinase 5 decreases expression EXP Arbutin results in decreased expression of MAP4K5 mRNA CTD PMID:17103032 NCBI chr14:50,418,521...50,561,126
Ensembl chr14:50,418,501...50,561,126 		JBrowse link
G MAPK8 mitogen-activated protein kinase 8 decreases expression EXP Arbutin results in decreased expression of MAPK8 mRNA CTD PMID:17103032 NCBI chr10:48,306,677...48,439,360
Ensembl chr10:48,306,639...48,439,360 		JBrowse link
G MCM8 minichromosome maintenance 8 homologous recombination repair factor increases expression EXP Arbutin results in increased expression of MCM8 mRNA CTD PMID:17103032 NCBI chr20:5,950,652...5,998,977
Ensembl chr20:5,950,652...5,998,977 		JBrowse link
G MDFI MyoD family inhibitor decreases expression EXP Arbutin results in decreased expression of MDFI mRNA CTD PMID:17103032 NCBI chr 6:41,637,018...41,654,244
Ensembl chr 6:41,636,882...41,654,244 		JBrowse link
G MFAP4 microfibril associated protein 4 decreases expression EXP Arbutin results in decreased expression of MFAP4 mRNA CTD PMID:17103032 NCBI chr17:19,383,445...19,387,190
Ensembl chr17:19,383,442...19,387,190 		JBrowse link
G MIDN midnolin decreases expression EXP Arbutin results in decreased expression of MIDN mRNA CTD PMID:17103032 NCBI chr19:1,248,583...1,259,143
Ensembl chr19:1,248,553...1,259,143 		JBrowse link
G MIR9-1HG MIR9-1 host gene decreases expression EXP Arbutin results in decreased expression of MIR9-1HG mRNA CTD PMID:17103032 NCBI chr 1:156,404,252...156,429,548
Ensembl chr 1:156,404,250...156,456,763 		JBrowse link
G MKI67 marker of proliferation Ki-67 increases expression EXP Arbutin results in increased expression of MKI67 mRNA CTD PMID:17103032 NCBI chr10:128,096,659...128,126,423
Ensembl chr10:128,096,659...128,126,423 		JBrowse link
G MMGT1 membrane magnesium transporter 1 increases expression EXP Arbutin results in increased expression of MMGT1 mRNA CTD PMID:17103032 NCBI chr  X:135,960,588...135,973,988
Ensembl chr  X:135,960,588...135,974,029 		JBrowse link
G MS4A6E membrane spanning 4-domains A6E decreases expression EXP Arbutin results in decreased expression of MS4A6E mRNA CTD PMID:17103032 NCBI chr11:60,327,255...60,349,072
Ensembl chr11:60,327,255...60,396,596 		JBrowse link
G MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like decreases expression EXP Arbutin results in decreased expression of MTHFD1L mRNA CTD PMID:17103032 NCBI chr 6:150,865,702...151,101,887
Ensembl chr 6:150,865,679...151,101,887 		JBrowse link
G MVD mevalonate diphosphate decarboxylase decreases expression EXP Arbutin results in decreased expression of MVD mRNA CTD PMID:17103032 NCBI chr16:88,651,940...88,663,091
Ensembl chr16:88,651,935...88,663,161 		JBrowse link
G MYO3B myosin IIIB decreases expression EXP Arbutin results in decreased expression of MYO3B mRNA CTD PMID:17103032 NCBI chr 2:170,178,147...170,655,167
Ensembl chr 2:170,178,145...170,655,171 		JBrowse link
G NCALD neurocalcin delta decreases expression EXP Arbutin results in decreased expression of NCALD mRNA CTD PMID:17103032 NCBI chr 8:101,686,542...102,124,907
Ensembl chr 8:101,686,542...102,124,907 		JBrowse link
G NEGR1 neuronal growth regulator 1 decreases expression EXP Arbutin results in decreased expression of NEGR1 mRNA CTD PMID:17103032 NCBI chr 1:71,395,943...72,282,539
Ensembl chr 1:71,395,943...72,282,539 		JBrowse link
G NEU4 neuraminidase 4 increases expression EXP Arbutin results in increased expression of NEU4 mRNA CTD PMID:17103032 NCBI chr 2:241,809,193...241,817,413
Ensembl chr 2:241,809,065...241,817,413 		JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 multiple interactions ISO Arbutin inhibits the reaction [Ethanol results in decreased expression of NFE2L2 mRNA] CTD PMID:34346143 NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756 		JBrowse link
G NKD1 NKD inhibitor of WNT signaling pathway 1 decreases expression EXP Arbutin results in decreased expression of NKD1 mRNA CTD PMID:17103032 NCBI chr16:50,548,396...50,649,249
Ensembl chr16:50,548,396...50,649,249 		JBrowse link
G NMI N-myc and STAT interactor increases expression EXP Arbutin results in increased expression of NMI mRNA CTD PMID:17103032 NCBI chr 2:151,270,470...151,289,668
Ensembl chr 2:151,270,470...151,289,894 		JBrowse link
G NOXRED1 NADP dependent oxidoreductase domain containing 1 decreases expression EXP Arbutin results in decreased expression of NOXRED1 mRNA CTD PMID:17103032 NCBI chr14:77,394,021...77,426,013
Ensembl chr14:77,394,021...77,423,523 		JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 multiple interactions ISO Arbutin inhibits the reaction [Ethanol results in increased expression of NQO1 mRNA] CTD PMID:34346143 NCBI chr16:69,709,401...69,726,560
Ensembl chr16:69,706,996...69,726,668 		JBrowse link
G NR2F1 nuclear receptor subfamily 2 group F member 1 increases expression EXP Arbutin results in increased expression of NR2F1 mRNA CTD PMID:17103032 NCBI chr 5:93,583,222...93,594,611
Ensembl chr 5:93,583,222...93,594,611 		JBrowse link
G NRP2 neuropilin 2 increases expression EXP Arbutin results in increased expression of NRP2 mRNA CTD PMID:17103032 NCBI chr 2:205,682,501...205,798,131
Ensembl chr 2:205,681,990...205,798,133 		JBrowse link
G NTF4 neurotrophin 4 decreases expression EXP Arbutin results in decreased expression of NTF4 mRNA CTD PMID:17103032 NCBI chr19:49,058,284...49,065,035
Ensembl chr19:49,061,066...49,065,076 		JBrowse link
G OLFML1 olfactomedin like 1 decreases expression EXP Arbutin results in decreased expression of OLFML1 mRNA CTD PMID:17103032 NCBI chr11:7,485,506...7,511,377
Ensembl chr11:7,485,388...7,511,377 		JBrowse link
G OSBP2 oxysterol binding protein 2 decreases expression EXP Arbutin results in decreased expression of OSBP2 mRNA CTD PMID:17103032 NCBI chr22:30,693,782...30,907,813
Ensembl chr22:30,693,782...30,907,824 		JBrowse link
G OSBPL11 oxysterol binding protein like 11 increases expression EXP Arbutin results in increased expression of OSBPL11 mRNA CTD PMID:17103032 NCBI chr 3:125,528,858...125,595,497
Ensembl chr 3:125,528,858...125,595,497 		JBrowse link
G OTX1 orthodenticle homeobox 1 decreases expression EXP Arbutin results in decreased expression of OTX1 mRNA CTD PMID:17103032 NCBI chr 2:63,049,735...63,057,831
Ensembl chr 2:63,050,057...63,057,836 		JBrowse link
G PACSIN2 protein kinase C and casein kinase substrate in neurons 2 decreases expression EXP Arbutin results in decreased expression of PACSIN2 mRNA CTD PMID:17103032 NCBI chr22:42,869,766...43,015,149
Ensembl chr22:42,835,412...43,015,149 		JBrowse link
G PARG poly(ADP-ribose) glycohydrolase increases expression EXP Arbutin results in increased expression of PARG mRNA CTD PMID:17103032 NCBI chr10:49,818,279...49,942,027
Ensembl chr10:49,818,279...49,970,203 		JBrowse link
G PCGF6 polycomb group ring finger 6 increases expression EXP Arbutin results in increased expression of PCGF6 mRNA CTD PMID:17103032 NCBI chr10:103,302,796...103,351,140
Ensembl chr10:103,302,796...103,351,144 		JBrowse link
G PCMTD2 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 increases expression EXP Arbutin results in increased expression of PCMTD2 mRNA CTD PMID:17103032 NCBI chr20:64,255,748...64,276,226
Ensembl chr20:64,255,695...64,304,820 		JBrowse link
G PCNX2 pecanex 2 decreases expression EXP Arbutin results in decreased expression of PCNX2 mRNA CTD PMID:17103032 NCBI chr 1:232,983,435...233,327,329
Ensembl chr 1:232,983,435...233,295,725 		JBrowse link
G PDZK1 PDZ domain containing 1 decreases expression EXP Arbutin results in decreased expression of PDZK1 mRNA CTD PMID:17103032 NCBI chr 1:145,670,852...145,707,400
Ensembl chr 1:145,670,852...145,708,148 		JBrowse link
G PERM1 PPARGC1 and ESRR induced regulator, muscle 1 decreases expression EXP Arbutin results in decreased expression of PERM1 mRNA CTD PMID:17103032 NCBI chr 1:975,198...982,093
Ensembl chr 1:975,198...982,117 		JBrowse link
G PF4 platelet factor 4 decreases expression EXP Arbutin results in decreased expression of PF4 mRNA CTD PMID:17103032 NCBI chr 4:73,980,811...73,982,124
Ensembl chr 4:73,980,811...73,982,027 		JBrowse link
G PGM2 phosphoglucomutase 2 increases expression EXP Arbutin results in increased expression of PGM2 mRNA CTD PMID:17103032 NCBI chr 4:37,826,686...37,862,937
Ensembl chr 4:37,826,660...37,862,937 		JBrowse link
G PIGQ phosphatidylinositol glycan anchor biosynthesis class Q decreases expression EXP Arbutin results in decreased expression of PIGQ mRNA CTD PMID:17103032 NCBI chr16:569,968...584,109
Ensembl chr16:566,995...584,109 		JBrowse link
G PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 decreases expression EXP Arbutin results in decreased expression of PIN1 mRNA CTD PMID:17103032 NCBI chr19:9,835,318...9,849,689
Ensembl chr19:9,835,257...9,849,689 		JBrowse link
G PITPNB phosphatidylinositol transfer protein beta increases expression EXP Arbutin results in increased expression of PITPNB mRNA CTD PMID:17103032 NCBI chr22:27,851,669...27,919,256
Ensembl chr22:27,851,669...27,920,134 		JBrowse link
G PKHD1 PKHD1 ciliary IPT domain containing fibrocystin/polyductin decreases expression EXP Arbutin results in decreased expression of PKHD1 mRNA CTD PMID:17103032 NCBI chr 6:51,615,299...52,087,615
Ensembl chr 6:51,615,299...52,087,613 		JBrowse link
G POGLUT2 protein O-glucosyltransferase 2 increases expression EXP Arbutin results in increased expression of POGLUT2 mRNA CTD PMID:17103032 NCBI chr13:102,784,281...102,798,976
Ensembl chr13:102,784,281...102,799,040 		JBrowse link
G POLE2 DNA polymerase epsilon 2, accessory subunit increases expression EXP Arbutin results in increased expression of POLE2 mRNA CTD PMID:17103032 NCBI chr14:49,643,555...49,688,214
Ensembl chr14:49,643,555...49,688,422 		JBrowse link
G PPHLN1 periphilin 1 increases expression EXP Arbutin results in increased expression of PPHLN1 mRNA CTD PMID:17103032 NCBI chr12:42,326,167...42,448,621
Ensembl chr12:42,238,447...42,459,715 		JBrowse link
G PRG2 proteoglycan 2, pro eosinophil major basic protein decreases expression EXP Arbutin results in decreased expression of PRG2 mRNA CTD PMID:17103032 NCBI chr11:57,386,780...57,390,650
Ensembl chr11:57,386,780...57,390,650 		JBrowse link
G PRKX protein kinase cAMP-dependent X-linked catalytic subunit decreases expression EXP Arbutin results in decreased expression of PRKX mRNA CTD PMID:17103032 NCBI chr  X:3,604,340...3,713,649
Ensembl chr  X:3,604,340...3,713,649 		JBrowse link
G PRMT2 protein arginine methyltransferase 2 decreases expression EXP Arbutin results in decreased expression of PRMT2 mRNA CTD PMID:17103032 NCBI chr21:46,635,674...46,665,124
Ensembl chr21:46,635,595...46,665,124 		JBrowse link
G PRR18 proline rich 18 decreases expression EXP Arbutin results in decreased expression of PRR18 mRNA CTD PMID:17103032 NCBI chr 6:166,305,300...166,308,392
Ensembl chr 6:166,305,300...166,308,448 		JBrowse link
G PRRX1 paired related homeobox 1 decreases expression EXP Arbutin results in decreased expression of PRRX1 mRNA CTD PMID:17103032 NCBI chr 1:170,662,768...170,739,421
Ensembl chr 1:170,662,728...170,739,421 		JBrowse link
G PRSS2 serine protease 2 decreases expression EXP Arbutin results in decreased expression of PRSS2 mRNA CTD PMID:17103032 NCBI chr 7:142,770,970...142,774,560
Ensembl chr 7:142,760,398...142,774,564 		JBrowse link
G PSMD13 proteasome 26S subunit, non-ATPase 13 decreases expression EXP Arbutin results in decreased expression of PSMD13 mRNA CTD PMID:17103032 NCBI chr11:236,976...252,984
Ensembl chr11:236,966...252,984 		JBrowse link
G PSMD3 proteasome 26S subunit, non-ATPase 3 decreases expression EXP Arbutin results in decreased expression of PSMD3 mRNA CTD PMID:17103032 NCBI chr17:39,980,807...39,997,959
Ensembl chr17:39,980,807...39,997,959 		JBrowse link
G RAB3GAP1 RAB3 GTPase activating protein catalytic subunit 1 increases expression EXP Arbutin results in increased expression of RAB3GAP1 mRNA CTD PMID:17103032 NCBI chr 2:135,052,292...135,176,396
Ensembl chr 2:135,052,289...135,176,667 		JBrowse link
G RAB6B RAB6B, member RAS oncogene family decreases expression EXP Arbutin results in decreased expression of RAB6B mRNA CTD PMID:17103032 NCBI chr 3:133,824,235...133,895,882
Ensembl chr 3:133,824,235...133,895,882 		JBrowse link
G RASGEF1B RasGEF domain family member 1B decreases expression EXP Arbutin results in decreased expression of RASGEF1B mRNA CTD PMID:17103032 NCBI chr 4:81,426,393...81,471,907
Ensembl chr 4:81,426,393...82,044,244 		JBrowse link
G RFPL2 ret finger protein like 2 decreases expression EXP Arbutin results in decreased expression of RFPL2 mRNA CTD PMID:17103032 NCBI chr22:32,190,438...32,205,073
Ensembl chr22:32,190,435...32,205,073 		JBrowse link
G RFPL3 ret finger protein like 3 decreases expression EXP Arbutin results in decreased expression of RFPL3 mRNA CTD PMID:17103032 NCBI chr22:32,354,885...32,361,161
Ensembl chr22:32,354,885...32,361,161 		JBrowse link
G RNF208 ring finger protein 208 decreases expression EXP Arbutin results in decreased expression of RNF208 mRNA CTD PMID:17103032 NCBI chr 9:137,220,259...137,223,408
Ensembl chr 9:137,220,247...137,222,240 		JBrowse link
G RPS6KA3 ribosomal protein S6 kinase A3 increases expression EXP Arbutin results in increased expression of RPS6KA3 mRNA CTD PMID:17103032 NCBI chr  X:20,149,911...20,267,097
Ensembl chr  X:20,149,911...20,267,519 		JBrowse link
G RSBN1 round spermatid basic protein 1 decreases expression EXP Arbutin results in decreased expression of RSBN1 mRNA CTD PMID:17103032 NCBI chr 1:113,761,832...113,812,476
Ensembl chr 1:113,761,832...113,812,476 		JBrowse link
G SAA4 serum amyloid A4, constitutive decreases expression EXP Arbutin results in decreased expression of SAA4 mRNA CTD PMID:17103032 NCBI chr11:18,231,355...18,236,802
Ensembl chr11:18,231,355...18,236,802 		JBrowse link
G SCCPDH saccharopine dehydrogenase (putative) increases expression EXP Arbutin results in increased expression of SCCPDH mRNA CTD PMID:17103032 NCBI chr 1:246,724,409...246,768,137
Ensembl chr 1:246,724,409...246,768,137 		JBrowse link
G SCN1B sodium voltage-gated channel beta subunit 1 increases expression EXP Arbutin results in increased expression of SCN1B mRNA CTD PMID:17103032 NCBI chr19:35,030,470...35,040,449
Ensembl chr19:35,030,470...35,040,449 		JBrowse link
G SDC4 syndecan 4 decreases expression EXP Arbutin results in decreased expression of SDC4 mRNA CTD PMID:17103032 NCBI chr20:45,325,288...45,348,424
Ensembl chr20:45,325,288...45,348,424 		JBrowse link
G SEMG1 semenogelin 1 decreases expression EXP Arbutin results in decreased expression of SEMG1 mRNA CTD PMID:17103032 NCBI chr20:45,207,033...45,209,768
Ensembl chr20:45,207,033...45,209,768 		JBrowse link
G SERPINA5 serpin family A member 5 decreases expression EXP Arbutin results in decreased expression of SERPINA5 mRNA CTD PMID:17103032 NCBI chr14:94,581,426...94,593,118
Ensembl chr14:94,561,442...94,593,118 		JBrowse link
G SERPIND1 serpin family D member 1 decreases expression EXP Arbutin results in decreased expression of SERPIND1 mRNA CTD PMID:17103032 NCBI chr22:20,774,113...20,787,720
Ensembl chr22:20,774,113...20,787,720 		JBrowse link
G SF3B1 splicing factor 3b subunit 1 increases expression EXP Arbutin results in increased expression of SF3B1 mRNA CTD PMID:17103032 NCBI chr 2:197,389,784...197,435,093
Ensembl chr 2:197,388,515...197,435,079 		JBrowse link
G SFRP5 secreted frizzled related protein 5 decreases expression EXP Arbutin results in decreased expression of SFRP5 mRNA CTD PMID:17103032 NCBI chr10:97,766,751...97,771,999
Ensembl chr10:97,766,751...97,771,999 		JBrowse link
G SFXN2 sideroflexin 2 decreases expression EXP Arbutin results in decreased expression of SFXN2 mRNA CTD PMID:17103032 NCBI chr10:102,714,636...102,743,492
Ensembl chr10:102,714,538...102,743,492 		JBrowse link
G SH3GL2 SH3 domain containing GRB2 like 2, endophilin A1 decreases expression EXP Arbutin results in decreased expression of SH3GL2 mRNA CTD PMID:17103032 NCBI chr 9:17,579,066...17,797,124
Ensembl chr 9:17,579,066...17,797,124 		JBrowse link
G SIN3B SIN3 transcription regulator family member B decreases expression EXP Arbutin results in decreased expression of SIN3B mRNA CTD PMID:17103032 NCBI chr19:16,829,398...16,880,349
Ensembl chr19:16,829,398...16,880,353 		JBrowse link
G SLC13A2 solute carrier family 13 member 2 decreases expression EXP Arbutin results in decreased expression of SLC13A2 mRNA CTD PMID:17103032 NCBI chr17:28,473,644...28,497,781
Ensembl chr17:28,473,293...28,497,781 		JBrowse link
G SLC15A3 solute carrier family 15 member 3 decreases expression EXP Arbutin results in decreased expression of SLC15A3 mRNA CTD PMID:17103032 NCBI chr11:60,937,084...60,952,176
Ensembl chr11:60,937,060...60,952,653 		JBrowse link
G SLC18A2 solute carrier family 18 member A2 decreases expression EXP Arbutin results in decreased expression of SLC18A2 mRNA CTD PMID:17103032 NCBI chr10:117,241,114...117,279,430
Ensembl chr10:117,241,093...117,279,430 		JBrowse link
G SLC23A3 solute carrier family 23 member 3 increases expression EXP Arbutin results in increased expression of SLC23A3 mRNA CTD PMID:17103032 NCBI chr 2:219,161,465...219,170,029
Ensembl chr 2:219,161,465...219,170,095 		JBrowse link
G SLC25A2 solute carrier family 25 member 2 decreases expression EXP Arbutin results in decreased expression of SLC25A2 mRNA CTD PMID:17103032 NCBI chr 5:141,302,635...141,304,049
Ensembl chr 5:141,302,635...141,304,049 		JBrowse link
G SLC27A4 solute carrier family 27 member 4 decreases expression EXP Arbutin results in decreased expression of SLC27A4 mRNA CTD PMID:17103032 NCBI chr 9:128,340,527...128,361,470
Ensembl chr 9:128,340,527...128,361,470 		JBrowse link
G SLC7A3 solute carrier family 7 member 3 decreases expression EXP Arbutin results in decreased expression of SLC7A3 mRNA CTD PMID:17103032 NCBI chr  X:70,925,579...70,931,096
Ensembl chr  X:70,925,579...70,931,125 		JBrowse link
G SLCO5A1 solute carrier organic anion transporter family member 5A1 decreases expression EXP Arbutin results in decreased expression of SLCO5A1 mRNA CTD PMID:17103032 NCBI chr 8:69,667,046...69,834,978
Ensembl chr 8:69,667,046...69,834,978 		JBrowse link
G SNIP1 Smad nuclear interacting protein 1 decreases expression EXP Arbutin results in decreased expression of SNIP1 mRNA CTD PMID:17103032 NCBI chr 1:37,534,449...37,554,293
Ensembl chr 1:37,534,449...37,554,293 		JBrowse link
G SOCS4 suppressor of cytokine signaling 4 decreases expression EXP Arbutin results in decreased expression of SOCS4 mRNA CTD PMID:17103032 NCBI chr14:55,027,236...55,049,489
Ensembl chr14:55,027,230...55,049,489 		JBrowse link
G SOD1 superoxide dismutase 1 multiple interactions ISO Arbutin inhibits the reaction [potassium bromate results in decreased activity of SOD1 protein] CTD PMID:36284482 NCBI chr21:31,659,693...31,668,931
Ensembl chr21:31,659,666...31,668,931 		JBrowse link
G SPATA13 spermatogenesis associated 13 increases expression EXP Arbutin results in increased expression of SPATA13 mRNA CTD PMID:17103032 NCBI chr13:23,979,802...24,307,069
Ensembl chr13:23,979,805...24,307,074
Ensembl chr13:23,979,805...24,307,074 		JBrowse link
G SPATA20 spermatogenesis associated 20 decreases expression EXP Arbutin results in decreased expression of SPATA20 mRNA CTD PMID:17103032 NCBI chr17:50,547,174...50,555,852
Ensembl chr17:50,543,058...50,555,852 		JBrowse link
G SPTLC1 serine palmitoyltransferase long chain base subunit 1 increases expression EXP Arbutin results in increased expression of SPTLC1 mRNA CTD PMID:17103032 NCBI chr 9:92,031,147...92,115,413
Ensembl chr 9:92,000,087...92,115,413 		JBrowse link
G SRD5A1 steroid 5 alpha-reductase 1 decreases activity
decreases expression		 ISO Arbutin results in decreased activity of SRD5A1 protein
Arbutin results in decreased expression of SRD5A1 mRNA; Arbutin results in decreased expression of SRD5A1 protein		 CTD PMID:37783241 NCBI chr 5:6,633,440...6,674,386
Ensembl chr 5:6,633,290...6,676,539 		JBrowse link
G STARD8 StAR related lipid transfer domain containing 8 decreases expression EXP Arbutin results in decreased expression of STARD8 mRNA CTD PMID:17103032 NCBI chr  X:68,647,666...68,725,836
Ensembl chr  X:68,647,666...68,725,842 		JBrowse link
G SYDE1 synapse defective Rho GTPase homolog 1 decreases expression EXP Arbutin results in decreased expression of SYDE1 mRNA CTD PMID:17103032 NCBI chr19:15,107,401...15,114,974
Ensembl chr19:15,107,401...15,114,985 		JBrowse link
G SYMPK symplekin scaffold protein decreases expression EXP Arbutin results in decreased expression of SYMPK mRNA CTD PMID:17103032 NCBI chr19:45,815,410...45,863,147
Ensembl chr19:45,815,410...45,863,225 		JBrowse link
G TAL1 TAL bHLH transcription factor 1, erythroid differentiation factor decreases expression EXP Arbutin results in decreased expression of TAL1 mRNA CTD PMID:17103032 NCBI chr 1:47,216,290...47,232,335
Ensembl chr 1:47,216,290...47,232,225 		JBrowse link
G TARDBP TAR DNA binding protein increases expression EXP Arbutin results in increased expression of TARDBP mRNA CTD PMID:17103032 NCBI chr 1:11,012,654...11,030,528
Ensembl chr 1:11,012,344...11,030,528 		JBrowse link
G TCF12 transcription factor 12 increases expression EXP Arbutin results in increased expression of TCF12 mRNA CTD PMID:17103032 NCBI chr15:56,918,090...57,291,310
Ensembl chr15:56,918,623...57,299,281 		JBrowse link
G TCN1 transcobalamin 1 decreases expression EXP Arbutin results in decreased expression of TCN1 mRNA CTD PMID:17103032 NCBI chr11:59,852,808...59,866,487
Ensembl chr11:59,852,800...59,866,489 		JBrowse link
G TES testin LIM domain protein increases expression EXP Arbutin results in increased expression of TES mRNA CTD PMID:17103032 NCBI chr 7:116,210,539...116,258,783
Ensembl chr 7:116,210,506...116,258,783 		JBrowse link
G TEX13B testis expressed 13B decreases expression EXP Arbutin results in decreased expression of TEX13B mRNA CTD PMID:17103032 NCBI chr  X:107,980,864...107,982,370
Ensembl chr  X:107,980,864...107,982,370 		JBrowse link
G TGFB3 transforming growth factor beta 3 decreases expression EXP Arbutin results in decreased expression of TGFB3 mRNA CTD PMID:17103032 NCBI chr14:75,958,097...75,983,011
Ensembl chr14:75,958,097...75,983,011 		JBrowse link
G TLL1 tolloid like 1 decreases expression EXP Arbutin results in decreased expression of TLL1 mRNA CTD PMID:17103032 NCBI chr 4:165,873,237...166,104,457
Ensembl chr 4:165,873,237...166,104,457 		JBrowse link
G TMEM59L transmembrane protein 59 like decreases expression EXP Arbutin results in decreased expression of TMEM59L mRNA CTD PMID:17103032 NCBI chr19:18,612,870...18,621,039
Ensembl chr19:18,607,430...18,621,039 		JBrowse link
G TNF tumor necrosis factor multiple interactions ISO Arbutin inhibits the reaction [Ethanol results in increased expression of TNF protein] CTD PMID:34346143 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TOR4A torsin family 4 member A decreases expression EXP Arbutin results in decreased expression of TOR4A mRNA CTD PMID:17103032 NCBI chr 9:137,277,726...137,282,641
Ensembl chr 9:137,277,726...137,282,641 		JBrowse link
G TRAM2 translocation associated membrane protein 2 decreases expression EXP Arbutin results in decreased expression of TRAM2 mRNA CTD PMID:17103032 NCBI chr 6:52,497,408...52,577,060
Ensembl chr 6:52,497,408...52,577,060 		JBrowse link
G TREH trehalase decreases expression EXP Arbutin results in decreased expression of TREH mRNA CTD PMID:17103032 NCBI chr11:118,657,316...118,679,650
Ensembl chr11:118,657,316...118,679,690 		JBrowse link
G TSC1 TSC complex subunit 1 increases expression EXP Arbutin results in increased expression of TSC1 mRNA CTD PMID:17103032 NCBI chr 9:132,891,349...132,945,378
Ensembl chr 9:132,891,348...132,946,874 		JBrowse link
G TSC22D2 TSC22 domain family member 2 decreases expression EXP Arbutin results in decreased expression of TSC22D2 mRNA CTD PMID:17103032 NCBI chr 3:150,408,298...150,466,422
Ensembl chr 3:150,408,298...150,466,422 		JBrowse link
G TSHZ2 teashirt zinc finger homeobox 2 decreases expression EXP Arbutin results in decreased expression of TSHZ2 mRNA CTD PMID:17103032 NCBI chr20:52,972,358...53,495,330
Ensembl chr20:52,972,358...53,495,330 		JBrowse link
G TSPOAP1 TSPO associated protein 1 decreases expression EXP Arbutin results in decreased expression of TSPOAP1 mRNA CTD PMID:17103032 NCBI chr17:58,301,231...58,328,795
Ensembl chr17:58,301,228...58,328,795 		JBrowse link
G TTC22 tetratricopeptide repeat domain 22 decreases expression EXP Arbutin results in decreased expression of TTC22 mRNA CTD PMID:17103032 NCBI chr 1:54,779,712...54,801,323
Ensembl chr 1:54,779,712...54,801,323 		JBrowse link
G TULP3 TUB like protein 3 decreases expression EXP Arbutin results in decreased expression of TULP3 mRNA CTD PMID:17103032 NCBI chr12:2,890,891...2,941,138
Ensembl chr12:2,877,223...2,941,138 		JBrowse link
G TYR tyrosinase decreases expression
decreases activity		 ISO Arbutin results in decreased expression of TYR mRNA
Arbutin results in decreased activity of TYR protein		 CTD PMID:21071833 PMID:22705713 NCBI chr11:89,177,875...89,295,759
Ensembl chr11:89,177,875...89,295,759 		JBrowse link
G UBE2D4 ubiquitin conjugating enzyme E2 D4 (putative) decreases expression EXP Arbutin results in decreased expression of UBE2D4 mRNA CTD PMID:17103032 NCBI chr 7:43,926,436...43,956,136
Ensembl chr 7:43,926,436...43,956,136 		JBrowse link
G UBE2M ubiquitin conjugating enzyme E2 M decreases expression EXP Arbutin results in decreased expression of UBE2M mRNA CTD PMID:17103032 NCBI chr19:58,555,712...58,558,611
Ensembl chr19:58,555,712...58,558,954 		JBrowse link
G UBQLN1 ubiquilin 1 increases expression EXP Arbutin results in increased expression of UBQLN1 mRNA CTD PMID:17103032 NCBI chr 9:83,659,968...83,707,958
Ensembl chr 9:83,659,968...83,707,958 		JBrowse link
G USP44 ubiquitin specific peptidase 44 decreases expression EXP Arbutin results in decreased expression of USP44 mRNA CTD PMID:17103032 NCBI chr12:95,516,560...95,551,681
Ensembl chr12:95,516,560...95,551,476 		JBrowse link
G UTP11 UTP11 small subunit processome component increases expression EXP Arbutin results in increased expression of UTP11 mRNA CTD PMID:17103032 NCBI chr 1:38,012,734...38,024,820
Ensembl chr 1:38,009,258...38,024,820 		JBrowse link
G VPS13B vacuolar protein sorting 13 homolog B decreases expression EXP Arbutin results in decreased expression of VPS13B mRNA CTD PMID:17103032 NCBI chr 8:99,013,274...99,877,580
Ensembl chr 8:99,013,266...99,877,580 		JBrowse link
G VPS39 VPS39 subunit of HOPS complex increases expression EXP Arbutin results in increased expression of VPS39 mRNA CTD PMID:17103032 NCBI chr15:42,158,701...42,208,304
Ensembl chr15:42,158,701...42,208,307 		JBrowse link
G VWA3A von Willebrand factor A domain containing 3A decreases expression EXP Arbutin results in decreased expression of VWA3A mRNA CTD PMID:17103032 NCBI chr16:22,092,541...22,156,964
Ensembl chr16:22,092,538...22,156,964 		JBrowse link
G WNT10A Wnt family member 10A decreases expression EXP Arbutin results in decreased expression of WNT10A mRNA CTD PMID:17103032 NCBI chr 2:218,874,116...218,893,928
Ensembl chr 2:218,880,852...218,899,581 		JBrowse link
G XAGE2 X antigen family member 2 increases expression EXP Arbutin results in increased expression of XAGE2 mRNA CTD PMID:17103032 NCBI chr  X:52,369,021...52,375,680
Ensembl chr  X:52,369,021...52,375,680 		JBrowse link
G ZBTB20 zinc finger and BTB domain containing 20 increases expression EXP Arbutin results in increased expression of ZBTB20 mRNA CTD PMID:17103032 NCBI chr 3:114,314,500...115,147,288
Ensembl chr 3:114,314,500...115,147,292 		JBrowse link
G ZBTB7B zinc finger and BTB domain containing 7B decreases expression EXP Arbutin results in decreased expression of ZBTB7B mRNA CTD PMID:17103032 NCBI chr 1:155,001,750...155,018,523
Ensembl chr 1:155,002,630...155,018,523 		JBrowse link
G ZDHHC2 zinc finger DHHC-type palmitoyltransferase 2 decreases expression EXP Arbutin results in decreased expression of ZDHHC2 mRNA CTD PMID:17103032 NCBI chr 8:17,156,482...17,224,799
Ensembl chr 8:17,156,482...17,224,799 		JBrowse link
G ZKSCAN7 zinc finger with KRAB and SCAN domains 7 decreases expression EXP Arbutin results in decreased expression of ZKSCAN7 mRNA CTD PMID:17103032 NCBI chr 3:44,555,193...44,583,483
Ensembl chr 3:44,555,193...44,594,173 		JBrowse link
G ZNF141 zinc finger protein 141 decreases expression EXP Arbutin results in decreased expression of ZNF141 mRNA CTD PMID:17103032 NCBI chr 4:337,814...384,868
Ensembl chr 4:337,814...384,868 		JBrowse link
G ZNF320 zinc finger protein 320 decreases expression EXP Arbutin results in decreased expression of ZNF320 mRNA CTD PMID:17103032 NCBI chr19:52,859,491...52,904,320
Ensembl chr19:52,860,851...52,897,693 		JBrowse link
G ZNF354B zinc finger protein 354B decreases expression EXP Arbutin results in decreased expression of ZNF354B mRNA CTD PMID:17103032 NCBI chr 5:178,859,953...178,885,020
Ensembl chr 5:178,859,953...178,888,122 		JBrowse link
G ZNF41 zinc finger protein 41 decreases expression EXP Arbutin results in decreased expression of ZNF41 mRNA CTD PMID:17103032 NCBI chr  X:47,445,178...47,483,222
Ensembl chr  X:47,445,178...47,483,222 		JBrowse link
G ZNF414 zinc finger protein 414 decreases expression EXP Arbutin results in decreased expression of ZNF414 mRNA CTD PMID:17103032 NCBI chr19:8,509,678...8,514,167
Ensembl chr19:8,509,678...8,514,167 		JBrowse link
G ZNF483 zinc finger protein 483 decreases expression EXP Arbutin results in decreased expression of ZNF483 mRNA CTD PMID:17103032 NCBI chr 9:111,525,179...111,578,136
Ensembl chr 9:111,525,159...111,577,844 		JBrowse link
G ZNF497 zinc finger protein 497 decreases expression EXP Arbutin results in decreased expression of ZNF497 mRNA CTD PMID:17103032 NCBI chr19:58,354,357...58,362,751
Ensembl chr19:58,354,357...58,362,848 		JBrowse link
G ZNF670 zinc finger protein 670 increases expression EXP Arbutin results in increased expression of ZNF670 mRNA CTD PMID:17103032 NCBI chr 1:247,034,637...247,078,811
Ensembl chr 1:247,034,637...247,078,811 		JBrowse link
G ZNF81 zinc finger protein 81 decreases expression EXP Arbutin results in decreased expression of ZNF81 mRNA CTD PMID:17103032 NCBI chr  X:47,836,902...47,925,627
Ensembl chr  X:47,836,902...48,002,561 		JBrowse link
G ZP2 zona pellucida glycoprotein 2 decreases expression EXP Arbutin results in decreased expression of ZP2 mRNA CTD PMID:17103032 NCBI chr16:21,197,450...21,214,510
Ensembl chr16:21,197,450...21,214,510 		JBrowse link
kaempferol 3-O-beta-D-glucoside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APP amyloid beta precursor protein multiple interactions ISO astragalin inhibits the reaction [[Galactose co-treated with Aluminum Chloride] results in decreased expression of APP protein] CTD PMID:35537655 NCBI chr21:25,880,550...26,171,128
Ensembl chr21:25,880,535...26,171,128 		JBrowse link
G CAT catalase multiple interactions ISO astragalin inhibits the reaction [[Galactose co-treated with Aluminum Chloride] results in decreased expression of CAT protein] CTD PMID:35537655 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060 		JBrowse link
G CCL2 C-C motif chemokine ligand 2 multiple interactions ISO astragalin inhibits the reaction [Lipopolysaccharides results in increased expression of CCL2 mRNA] CTD PMID:22210036 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208 		JBrowse link
G CCL3 C-C motif chemokine ligand 3 multiple interactions ISO astragalin inhibits the reaction [Lipopolysaccharides results in increased expression of CCL3 mRNA] CTD PMID:22210036 NCBI chr17:36,088,256...36,090,143
Ensembl chr17:36,088,256...36,090,169 		JBrowse link
G HES1 hes family bHLH transcription factor 1 multiple interactions ISO astragalin inhibits the reaction [[Galactose co-treated with Aluminum Chloride] results in increased expression of HES1 protein] CTD PMID:35537655 NCBI chr 3:194,136,148...194,138,732
Ensembl chr 3:194,136,148...194,138,732 		JBrowse link
G IL10 interleukin 10 multiple interactions ISO astragalin inhibits the reaction [[Galactose co-treated with Aluminum Chloride] results in decreased expression of IL10 protein] CTD PMID:35537655 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541 		JBrowse link
G IL1B interleukin 1 beta multiple interactions ISO astragalin inhibits the reaction [[Galactose co-treated with Aluminum Chloride] results in increased expression of IL1B protein]; astragalin inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA] CTD PMID:22210036 PMID:35537655 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL6 interleukin 6 multiple interactions ISO astragalin inhibits the reaction [[Galactose co-treated with Aluminum Chloride] results in increased expression of IL6 protein]; astragalin inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA] CTD PMID:22210036 PMID:35537655 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G NFKBIA NFKB inhibitor alpha multiple interactions ISO astragalin inhibits the reaction [Lipopolysaccharides results in increased degradation of NFKBIA protein] CTD PMID:22210036 NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749 		JBrowse link
G NOS2 nitric oxide synthase 2 multiple interactions ISO astragalin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; astragalin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein] CTD PMID:22210036 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529 		JBrowse link
G NOTCH1 notch receptor 1 multiple interactions ISO astragalin inhibits the reaction [[Galactose co-treated with Aluminum Chloride] results in increased expression of NOTCH1 protein] CTD PMID:35537655 NCBI chr 9:136,494,433...136,546,048
Ensembl chr 9:136,494,433...136,546,048 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO astragalin inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; astragalin inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein] CTD PMID:22210036 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922 		JBrowse link
G RBPJ recombination signal binding protein for immunoglobulin kappa J region multiple interactions ISO astragalin inhibits the reaction [[Galactose co-treated with Aluminum Chloride] results in increased expression of RBPJ protein] CTD PMID:35537655 NCBI chr 4:26,105,449...26,435,131
Ensembl chr 4:26,163,455...26,435,131 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit multiple interactions ISO astragalin inhibits the reaction [[Galactose co-treated with Aluminum Chloride] results in increased expression of and results in increased phosphorylation of RELA protein]; astragalin inhibits the reaction [Lipopolysaccharides results in increased localization of RELA protein] CTD PMID:22210036 PMID:35537655 NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090 		JBrowse link
G TNF tumor necrosis factor multiple interactions ISO astragalin inhibits the reaction [[Galactose co-treated with Aluminum Chloride] results in increased expression of TNF protein]; astragalin inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA] CTD PMID:22210036 PMID:35537655 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
liquiritin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB11 ATP binding cassette subfamily B member 11 multiple interactions ISO [liquiritin co-treated with 1-Naphthylisothiocyanate] results in increased expression of ABCB11 mRNA CTD PMID:36008890 NCBI chr 2:168,915,390...169,031,324
Ensembl chr 2:168,915,498...169,031,324 		JBrowse link
G ABCC2 ATP binding cassette subfamily C member 2 multiple interactions ISO [liquiritin co-treated with 1-Naphthylisothiocyanate] results in decreased expression of ABCC2 mRNA CTD PMID:36008890 NCBI chr10:99,782,640...99,852,594
Ensembl chr10:99,782,640...99,852,594 		JBrowse link
G ABCC3 ATP binding cassette subfamily C member 3 multiple interactions ISO [liquiritin co-treated with 1-Naphthylisothiocyanate] results in increased expression of ABCC3 mRNA CTD PMID:36008890 NCBI chr17:50,634,881...50,692,253
Ensembl chr17:50,634,777...50,692,253 		JBrowse link
G ABCC4 ATP binding cassette subfamily C member 4 (PEL blood group) multiple interactions ISO [liquiritin co-treated with 1-Naphthylisothiocyanate] results in increased expression of ABCC4 mRNA CTD PMID:36008890 NCBI chr13:95,019,835...95,301,451
Ensembl chr13:95,019,835...95,301,475 		JBrowse link
G CCL2 C-C motif chemokine ligand 2 multiple interactions ISO liquiritin inhibits the reaction [Monocrotaline results in increased expression of CCL2 mRNA]
liquiritin inhibits the reaction [HSPD1 protein results in increased expression of CCL2 mRNA]		 CTD PMID:31589899 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208 		JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 multiple interactions ISO [brucine co-treated with liquiritin] results in decreased activity of CYP2E1 protein CTD PMID:21800547 NCBI chr10:133,527,363...133,539,123
Ensembl chr10:133,520,406...133,561,220 		JBrowse link
G GCLC glutamate-cysteine ligase catalytic subunit multiple interactions
increases expression		 ISO liquiritin inhibits the reaction [Monocrotaline results in decreased expression of GCLC mRNA]
liquiritin results in increased expression of GCLC protein		 CTD PMID:29908794 NCBI chr 6:53,497,341...53,545,101
Ensembl chr 6:53,497,341...53,616,970 		JBrowse link
G GCLM glutamate-cysteine ligase modifier subunit increases expression
multiple interactions		 ISO liquiritin results in increased expression of GCLM protein
liquiritin inhibits the reaction [Monocrotaline results in decreased expression of GCLM mRNA]		 CTD PMID:29908794 NCBI chr 1:93,885,199...93,909,430
Ensembl chr 1:93,885,199...93,909,456 		JBrowse link
G GPT glutamic--pyruvic transaminase multiple interactions ISO liquiritin inhibits the reaction [Monocrotaline results in increased activity of GPT protein]
liquiritin inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of GPT protein]		 CTD PMID:31589899 PMID:36008890 NCBI chr 8:144,503,068...144,507,172
Ensembl chr 8:144,502,973...144,507,174 		JBrowse link
G GSR glutathione-disulfide reductase multiple interactions ISO liquiritin inhibits the reaction [Monocrotaline results in decreased expression of GSR mRNA]; liquiritin inhibits the reaction [Monocrotaline results in decreased expression of GSR protein] CTD PMID:29908794 NCBI chr 8:30,678,066...30,727,846
Ensembl chr 8:30,678,066...30,727,846 		JBrowse link
G HMOX1 heme oxygenase 1 multiple interactions ISO liquiritin inhibits the reaction [Monocrotaline results in increased expression of HMOX1 mRNA]
[liquiritin co-treated with 1-Naphthylisothiocyanate] results in increased expression of HMOX1 mRNA; liquiritin inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of HMOX1 protein]		 CTD PMID:29908794 PMID:36008890 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214 		JBrowse link
G HSPD1 heat shock protein family D (Hsp60) member 1 multiple interactions ISO liquiritin inhibits the reaction [Monocrotaline affects the expression of HSPD1 protein]
liquiritin inhibits the reaction [HSPD1 protein results in increased expression of CCL2 mRNA]; liquiritin inhibits the reaction [HSPD1 protein results in increased expression of IL6 mRNA]; liquiritin inhibits the reaction [HSPD1 protein results in increased expression of NOS2 mRNA]; liquiritin inhibits the reaction [HSPD1 protein results in increased expression of RELA protein]		 CTD PMID:31589899 NCBI chr 2:197,486,584...197,500,274
Ensembl chr 2:197,486,584...197,516,737 		JBrowse link
G IL1B interleukin 1 beta multiple interactions ISO liquiritin inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of IL1B protein] CTD PMID:36008890 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL6 interleukin 6 multiple interactions ISO liquiritin inhibits the reaction [Monocrotaline results in increased expression of IL6 mRNA]
liquiritin inhibits the reaction [HSPD1 protein results in increased expression of IL6 mRNA]		 CTD PMID:31589899 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G KEAP1 kelch like ECH associated protein 1 multiple interactions ISO liquiritin promotes the reaction [1-Naphthylisothiocyanate results in decreased expression of KEAP1 protein] CTD PMID:36008890 NCBI chr19:10,486,125...10,503,356
Ensembl chr19:10,486,125...10,503,558 		JBrowse link
G MMP9 matrix metallopeptidase 9 multiple interactions ISO liquiritin inhibits the reaction [Monocrotaline results in increased expression of MMP9 protein] CTD PMID:29908794 PMID:31589899 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561 		JBrowse link
G MPO myeloperoxidase multiple interactions ISO liquiritin inhibits the reaction [Monocrotaline results in increased activity of MPO protein] CTD PMID:31589899 NCBI chr17:58,269,855...58,280,935
Ensembl chr17:58,269,855...58,280,935 		JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 decreases response to substance
multiple interactions		 ISO NFE2L2 gene mutant form results in decreased susceptibility to liquiritin
liquiritin promotes the reaction [1-Naphthylisothiocyanate results in increased expression of NFE2L2 protein]
liquiritin inhibits the reaction [Monocrotaline results in decreased expression of NFE2L2 mRNA]		 CTD PMID:29908794 PMID:36008890 NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756 		JBrowse link
G NOS2 nitric oxide synthase 2 multiple interactions ISO liquiritin inhibits the reaction [Monocrotaline results in increased expression of NOS2 mRNA]
liquiritin inhibits the reaction [HSPD1 protein results in increased expression of NOS2 mRNA]		 CTD PMID:31589899 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529 		JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 multiple interactions ISO liquiritin inhibits the reaction [Monocrotaline results in decreased expression of NQO1 mRNA]
[liquiritin co-treated with 1-Naphthylisothiocyanate] results in increased expression of NQO1 mRNA		 CTD PMID:29908794 PMID:36008890 NCBI chr16:69,709,401...69,726,560
Ensembl chr16:69,706,996...69,726,668 		JBrowse link
G NR1H4 nuclear receptor subfamily 1 group H member 4 multiple interactions ISO liquiritin inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of NR1H4 mRNA]; liquiritin inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of NR1H4 protein] CTD PMID:36008890 NCBI chr12:100,473,866...100,564,414
Ensembl chr12:100,473,708...100,564,414 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit multiple interactions ISO liquiritin inhibits the reaction [Monocrotaline results in increased expression of RELA protein]
liquiritin inhibits the reaction [HSPD1 protein results in increased expression of RELA protein]		 CTD PMID:31589899 NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090 		JBrowse link
G SIRT1 sirtuin 1 multiple interactions ISO liquiritin inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of SIRT1 mRNA]; liquiritin inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of SIRT1 protein] CTD PMID:36008890 NCBI chr10:67,884,656...67,918,390
Ensembl chr10:67,884,656...67,918,390 		JBrowse link
G SLC10A1 solute carrier family 10 member 1 multiple interactions ISO liquiritin inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of SLC10A1 mRNA] CTD PMID:36008890 NCBI chr14:69,775,416...69,797,241
Ensembl chr14:69,775,416...69,797,241 		JBrowse link
G SQSTM1 sequestosome 1 multiple interactions ISO liquiritin inhibits the reaction [Monocrotaline results in increased expression of SQSTM1 protein] CTD PMID:29908794 NCBI chr 5:179,806,393...179,838,078
Ensembl chr 5:179,806,398...179,838,078 		JBrowse link
G TLR4 toll like receptor 4 multiple interactions ISO liquiritin inhibits the reaction [Monocrotaline results in increased expression of TLR4 protein] CTD PMID:31589899 NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735 		JBrowse link
G TNF tumor necrosis factor multiple interactions ISO liquiritin inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of TNF protein] CTD PMID:36008890 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TXN2 thioredoxin 2 multiple interactions ISO liquiritin inhibits the reaction [Monocrotaline results in decreased expression of TXN2 mRNA]; liquiritin inhibits the reaction [Monocrotaline results in decreased expression of TXN2 protein] CTD PMID:29908794 NCBI chr22:36,467,046...36,481,640
Ensembl chr22:36,467,046...36,481,640 		JBrowse link
G TXNRD2 thioredoxin reductase 2 multiple interactions ISO liquiritin inhibits the reaction [Monocrotaline results in decreased expression of TXNRD2 mRNA]; liquiritin inhibits the reaction [Monocrotaline results in decreased expression of TXNRD2 protein] CTD PMID:29908794 NCBI chr22:19,875,522...19,941,818
Ensembl chr22:19,875,517...19,941,820 		JBrowse link
loganin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACHE acetylcholinesterase (Yt blood group) decreases activity ISO loganin results in decreased activity of ACHE protein CTD PMID:19666019 NCBI chr 7:100,889,994...100,896,994
Ensembl chr 7:100,889,994...100,896,974 		JBrowse link
G ACTA2 actin alpha 2, smooth muscle multiple interactions ISO loganin inhibits the reaction [Bleomycin results in increased expression of ACTA2 mRNA]; loganin inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein] CTD PMID:35279615 NCBI chr10:88,935,074...88,991,337
Ensembl chr10:88,934,822...88,991,339 		JBrowse link
G BCL2 BCL2 apoptosis regulator increases expression ISO loganin results in increased expression of BCL2 mRNA CTD PMID:20966881 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128 		JBrowse link
G CASP1 caspase 1 multiple interactions EXP
ISO		 loganin inhibits the reaction [Glucose results in increased expression of CASP1 mRNA]; loganin inhibits the reaction [Glucose results in increased expression of CASP1 protein]
loganin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of CASP1 protein]		 CTD PMID:37473909 NCBI chr11:105,025,443...105,036,686
Ensembl chr11:105,025,397...105,035,250 		JBrowse link
G CASP3 caspase 3 decreases expression ISO loganin results in decreased expression of CASP3 mRNA CTD PMID:20966881 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062 		JBrowse link
G CASP9 caspase 9 decreases expression ISO loganin results in decreased expression of CASP9 mRNA CTD PMID:20966881 NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534 		JBrowse link
G CCL2 C-C motif chemokine ligand 2 affects expression ISO loganin affects the expression of CCL2 protein CTD PMID:21864639 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208 		JBrowse link
G CYBA cytochrome b-245 alpha chain affects expression ISO loganin affects the expression of CYBA protein CTD PMID:21864639 NCBI chr16:88,643,289...88,651,053
Ensembl chr16:88,643,275...88,651,083 		JBrowse link
G GSDMD gasdermin D multiple interactions ISO
EXP		 loganin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of GSDMD mRNA]; loganin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of GSDMD protein]
loganin inhibits the reaction [Glucose results in increased expression of GSDMD mRNA]; loganin inhibits the reaction [Glucose results in increased expression of GSDMD protein]		 CTD PMID:37473909 NCBI chr 8:143,553,387...143,563,062
Ensembl chr 8:143,553,207...143,563,062 		JBrowse link
G HMOX1 heme oxygenase 1 affects expression ISO loganin affects the expression of HMOX1 protein CTD PMID:21864639 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214 		JBrowse link
G IL18 interleukin 18 multiple interactions ISO
EXP		 loganin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of and results in increased secretion of IL18 protein]; loganin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of IL18 mRNA]
loganin inhibits the reaction [Glucose results in increased expression of IL18 mRNA]; loganin inhibits the reaction [Glucose results in increased expression of IL18 protein]		 CTD PMID:37473909 NCBI chr11:112,143,260...112,164,094
Ensembl chr11:112,143,253...112,164,096 		JBrowse link
G IL1B interleukin 1 beta multiple interactions ISO
EXP		 loganin inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]
loganin inhibits the reaction [Glucose results in increased expression of IL1B mRNA]; loganin inhibits the reaction [Glucose results in increased expression of IL1B protein]
loganin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of and results in increased secretion of IL1B protein]; loganin inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]		 CTD PMID:35279615 PMID:37473909 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL6 interleukin 6 multiple interactions ISO loganin inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA] CTD PMID:35279615 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G LEP leptin affects expression ISO loganin affects the expression of LEP protein CTD PMID:21864639 NCBI chr 7:128,241,278...128,257,629
Ensembl chr 7:128,241,278...128,257,629 		JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 affects expression ISO loganin affects the expression of NFE2L2 protein CTD PMID:21864639 NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756 		JBrowse link
G NLRP3 NLR family pyrin domain containing 3 multiple interactions EXP
ISO		 loganin inhibits the reaction [Glucose results in increased expression of NLRP3 mRNA]; loganin inhibits the reaction [Glucose results in increased expression of NLRP3 protein]
loganin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of NLRP3 mRNA]; loganin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of NLRP3 protein]		 CTD PMID:37473909 NCBI chr 1:247,416,077...247,448,817
Ensembl chr 1:247,332,331...247,449,108 		JBrowse link
G NOS2 nitric oxide synthase 2 affects expression ISO loganin affects the expression of NOS2 protein CTD PMID:21864639 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529 		JBrowse link
G NOX4 NADPH oxidase 4 affects expression ISO loganin affects the expression of NOX4 protein CTD PMID:21864639 NCBI chr11:89,324,353...89,589,557
Ensembl chr11:89,324,353...89,498,187 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 affects expression ISO loganin affects the expression of PTGS2 protein CTD PMID:21864639 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit affects expression
multiple interactions		 ISO loganin affects the expression of RELA protein
loganin inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased phosphorylation of RELA protein]		 CTD PMID:21864639 PMID:35279615 NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090 		JBrowse link
G STAT3 signal transducer and activator of transcription 3 multiple interactions ISO loganin inhibits the reaction [Lipopolysaccharides results in increased expression of STAT3 protein]
loganin inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased phosphorylation of STAT3 protein]		 CTD PMID:35279615 NCBI chr17:42,313,324...42,388,442
Ensembl chr17:42,313,324...42,388,568 		JBrowse link
G TGFB1 transforming growth factor beta 1 multiple interactions ISO loganin inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA] CTD PMID:35279615 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922 		JBrowse link
G TNF tumor necrosis factor multiple interactions ISO loganin inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA] CTD PMID:35279615 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TNFSF11 TNF superfamily member 11 decreases expression ISO loganin results in decreased expression of TNFSF11 mRNA CTD PMID:20966881 NCBI chr13:42,562,736...42,608,013
Ensembl chr13:42,562,736...42,608,013 		JBrowse link
luteolin 7-O-beta-D-glucoside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKT1 AKT serine/threonine kinase 1 multiple interactions
decreases phosphorylation		 EXP [luteolin-7-glucoside co-treated with Hydrogen Peroxide] results in increased phosphorylation of AKT1 protein
luteolin-7-glucoside results in decreased phosphorylation of AKT1 protein		 CTD PMID:31157476 PMID:34165247 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,759 		JBrowse link
G BAX BCL2 associated X, apoptosis regulator increases expression EXP luteolin-7-glucoside results in increased expression of BAX protein CTD PMID:34165247 NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798 		JBrowse link
G BCL2 BCL2 apoptosis regulator multiple interactions
decreases expression		 EXP luteolin-7-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of BCL2 protein]; luteolin-7-glucoside inhibits the reaction [Hydrogen Peroxide results in decreased expression of BCL2 protein]
luteolin-7-glucoside results in decreased expression of BCL2 protein		 CTD PMID:31157476 PMID:31381935 PMID:34165247 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128 		JBrowse link
G BCL2L1 BCL2 like 1 decreases expression EXP luteolin-7-glucoside results in decreased expression of BCL2L1 protein CTD PMID:34165247 NCBI chr20:31,664,452...31,723,963
Ensembl chr20:31,664,452...31,723,989 		JBrowse link
G BID BH3 interacting domain death agonist increases expression EXP luteolin-7-glucoside results in increased expression of BID protein alternative form CTD PMID:34165247 NCBI chr22:17,734,138...17,774,665
Ensembl chr22:17,734,138...17,774,770 		JBrowse link
G CASP3 caspase 3 multiple interactions
increases cleavage		 EXP benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone inhibits the reaction [luteolin-7-glucoside results in increased cleavage of CASP3 protein]; luteolin-7-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of CASP3 protein modified form]; luteolin-7-glucoside inhibits the reaction [Hydrogen Peroxide results in increased cleavage of CASP3 protein] CTD PMID:31157476 PMID:31381935 PMID:34165247 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062 		JBrowse link
G CASP8 caspase 8 increases cleavage EXP luteolin-7-glucoside results in increased cleavage of CASP8 protein CTD PMID:34165247 NCBI chr 2:201,233,463...201,287,711
Ensembl chr 2:201,233,443...201,361,836 		JBrowse link
G CASP9 caspase 9 increases cleavage EXP luteolin-7-glucoside results in increased cleavage of CASP9 protein CTD PMID:34165247 NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534 		JBrowse link
G CAT catalase multiple interactions EXP luteolin-7-glucoside inhibits the reaction [Hydrogen Peroxide results in decreased activity of CAT protein] CTD PMID:31157476 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060 		JBrowse link
G CCNA2 cyclin A2 decreases expression EXP luteolin-7-glucoside results in decreased expression of CCNA2 protein CTD PMID:34165247 NCBI chr 4:121,816,444...121,823,883
Ensembl chr 4:121,816,444...121,823,883 		JBrowse link
G CCNB1 cyclin B1 decreases expression EXP luteolin-7-glucoside results in decreased expression of CCNB1 protein CTD PMID:34165247 NCBI chr 5:69,167,150...69,178,245
Ensembl chr 5:69,167,135...69,178,245 		JBrowse link
G CDK1 cyclin dependent kinase 1 decreases phosphorylation EXP luteolin-7-glucoside results in decreased phosphorylation of CDK1 protein CTD PMID:34165247 NCBI chr10:60,778,331...60,794,852
Ensembl chr10:60,778,331...60,794,852 		JBrowse link
G CDK2 cyclin dependent kinase 2 decreases expression EXP luteolin-7-glucoside results in decreased expression of CDK2 protein CTD PMID:34165247 NCBI chr12:55,966,830...55,972,789
Ensembl chr12:55,966,781...55,972,789 		JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A increases expression EXP luteolin-7-glucoside results in increased expression of CDKN1A protein CTD PMID:34165247 NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,337 		JBrowse link
G ESR1 estrogen receptor 1 multiple interactions
increases activity		 EXP 1,3-bis(4-hydroxyphenyl)-4-methyl-5-(4-(2-piperidinylethoxy)phenol)-1H-pyrazole inhibits the reaction [luteolin-7-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased phosphorylation of ESR1 protein]]; Fulvestrant inhibits the reaction [luteolin-7-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased phosphorylation of ESR1 protein]]; luteolin-7-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased phosphorylation of ESR1 protein]
luteolin-7-glucoside results in increased activity of ESR1 protein		 CTD PMID:31381935 NCBI chr 6:151,656,672...152,129,619
Ensembl chr 6:151,656,691...152,129,619 		JBrowse link
G ESR2 estrogen receptor 2 increases activity
multiple interactions		 EXP luteolin-7-glucoside results in increased activity of ESR2 protein
4-(2-phenyl-5,7-bis(trifluoromethyl)pyrazolo(1,5-a)pyrimidin-3-yl)phenol inhibits the reaction [luteolin-7-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased phosphorylation of ESR2 protein]]; Fulvestrant inhibits the reaction [luteolin-7-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased phosphorylation of ESR2 protein]]; luteolin-7-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased phosphorylation of ESR2 protein]		 CTD PMID:31381935 NCBI chr14:64,226,707...64,338,613
Ensembl chr14:64,084,232...64,338,112 		JBrowse link
G FAS Fas cell surface death receptor increases expression EXP luteolin-7-glucoside results in increased expression of FAS protein CTD PMID:34165247 NCBI chr10:88,964,050...89,017,059
Ensembl chr10:88,953,813...89,029,605 		JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP 1,3-bis(4-hydroxyphenyl)-4-methyl-5-(4-(2-piperidinylethoxy)phenol)-1H-pyrazole inhibits the reaction [luteolin-7-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of FOS protein]]; 4-(2-phenyl-5,7-bis(trifluoromethyl)pyrazolo(1,5-a)pyrimidin-3-yl)phenol inhibits the reaction [luteolin-7-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of FOS protein]]; Fulvestrant inhibits the reaction [luteolin-7-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of FOS protein]]; luteolin-7-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of FOS protein] CTD PMID:31381935 NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,282,230 		JBrowse link
G IL6 interleukin 6 multiple interactions ISO luteolin-7-glucoside inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of IL6 protein] CTD PMID:11123379 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 decreases phosphorylation
multiple interactions		 EXP luteolin-7-glucoside results in decreased phosphorylation of MAPK1 protein
1,3-bis(4-hydroxyphenyl)-4-methyl-5-(4-(2-piperidinylethoxy)phenol)-1H-pyrazole inhibits the reaction [luteolin-7-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased phosphorylation of MAPK1 protein]]; 4-(2-phenyl-5,7-bis(trifluoromethyl)pyrazolo(1,5-a)pyrimidin-3-yl)phenol inhibits the reaction [luteolin-7-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased phosphorylation of MAPK1 protein]]; Fulvestrant inhibits the reaction [luteolin-7-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased phosphorylation of MAPK1 protein]]; luteolin-7-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased phosphorylation of MAPK1 protein]		 CTD PMID:31381935 PMID:34165247 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 multiple interactions
decreases phosphorylation		 EXP 1,3-bis(4-hydroxyphenyl)-4-methyl-5-(4-(2-piperidinylethoxy)phenol)-1H-pyrazole inhibits the reaction [luteolin-7-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased phosphorylation of MAPK3 protein]]; 4-(2-phenyl-5,7-bis(trifluoromethyl)pyrazolo(1,5-a)pyrimidin-3-yl)phenol inhibits the reaction [luteolin-7-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased phosphorylation of MAPK3 protein]]; Fulvestrant inhibits the reaction [luteolin-7-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased phosphorylation of MAPK3 protein]]; luteolin-7-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased phosphorylation of MAPK3 protein]
luteolin-7-glucoside results in decreased phosphorylation of MAPK3 protein		 CTD PMID:31381935 PMID:34165247 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506 		JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 multiple interactions
increases cleavage		 EXP 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [luteolin-7-glucoside results in increased cleavage of PARP1 protein]; benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone inhibits the reaction [luteolin-7-glucoside results in increased cleavage of PARP1 protein]; pyrazolanthrone inhibits the reaction [luteolin-7-glucoside results in increased cleavage of PARP1 protein]; SB 203580 promotes the reaction [luteolin-7-glucoside results in increased cleavage of PARP1 protein]; U 0126 inhibits the reaction [luteolin-7-glucoside results in increased cleavage of PARP1 protein] CTD PMID:34165247 NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154 		JBrowse link
G RIPK1 receptor interacting serine/threonine kinase 1 increases expression EXP luteolin-7-glucoside results in increased expression of RIPK1 protein CTD PMID:34165247 NCBI chr 6:3,063,967...3,115,187
Ensembl chr 6:3,063,824...3,115,187 		JBrowse link
G STAT3 signal transducer and activator of transcription 3 multiple interactions EXP 1,3-bis(4-hydroxyphenyl)-4-methyl-5-(4-(2-piperidinylethoxy)phenol)-1H-pyrazole inhibits the reaction [luteolin-7-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased phosphorylation of STAT3 protein]]; 4-(2-phenyl-5,7-bis(trifluoromethyl)pyrazolo(1,5-a)pyrimidin-3-yl)phenol inhibits the reaction [luteolin-7-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased phosphorylation of STAT3 protein]]; Fulvestrant inhibits the reaction [luteolin-7-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased phosphorylation of STAT3 protein]]; luteolin-7-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased phosphorylation of STAT3 protein] CTD PMID:31381935 NCBI chr17:42,313,324...42,388,442
Ensembl chr17:42,313,324...42,388,568 		JBrowse link
G TNF tumor necrosis factor multiple interactions ISO luteolin-7-glucoside inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of TNF protein] CTD PMID:11123379 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TNFRSF10B TNF receptor superfamily member 10b increases expression EXP luteolin-7-glucoside results in increased expression of TNFRSF10B protein CTD PMID:34165247 NCBI chr 8:23,020,133...23,069,031
Ensembl chr 8:23,020,133...23,069,031 		JBrowse link
G TNFRSF1A TNF receptor superfamily member 1A increases expression EXP luteolin-7-glucoside results in increased expression of TNFRSF1A protein CTD PMID:34165247 NCBI chr12:6,328,771...6,342,076
Ensembl chr12:6,328,757...6,342,114 		JBrowse link
malvidin 3-O-beta-D-glucoside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AQP3 aquaporin 3 (Gill blood group) multiple interactions EXP [malvidin-3-glucoside co-treated with petunidin-3-glucoside] results in increased expression of AQP3 mRNA CTD PMID:33294640 NCBI chr 9:33,441,160...33,447,593
Ensembl chr 9:33,441,156...33,447,596 		JBrowse link
G CA1 carbonic anhydrase 1 decreases activity EXP malvidin-3-glucoside results in decreased activity of CA1 protein CTD PMID:28445001 NCBI chr 8:85,327,608...85,378,113
Ensembl chr 8:85,327,608...85,379,014 		JBrowse link
G CA2 carbonic anhydrase 2 decreases activity EXP malvidin-3-glucoside results in decreased activity of CA2 protein CTD PMID:28445001 NCBI chr 8:85,464,007...85,481,493
Ensembl chr 8:85,463,968...85,481,493 		JBrowse link
G NOS2 nitric oxide synthase 2 multiple interactions ISO malvidin-3-glucoside inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein] CTD PMID:23731018 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529 		JBrowse link
G PDE5A phosphodiesterase 5A decreases activity EXP malvidin-3-glucoside results in decreased activity of PDE5A protein CTD PMID:15769121 NCBI chr 4:119,494,403...119,628,804
Ensembl chr 4:119,494,397...119,628,804 		JBrowse link
G SELE selectin E multiple interactions EXP malvidin-3-glucoside inhibits the reaction [TNF protein results in increased expression of SELE protein] CTD PMID:30611791 NCBI chr 1:169,722,640...169,734,079
Ensembl chr 1:169,722,640...169,764,705 		JBrowse link
G TNF tumor necrosis factor multiple interactions ISO
EXP		 malvidin-3-glucoside inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]
malvidin-3-glucoside inhibits the reaction [TNF protein results in increased expression of SELE protein]		 CTD PMID:23731018 PMID:30611791 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
malvin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CA1 carbonic anhydrase 1 decreases activity EXP malvin results in decreased activity of CA1 protein CTD PMID:28445001 NCBI chr 8:85,327,608...85,378,113
Ensembl chr 8:85,327,608...85,379,014 		JBrowse link
G CA2 carbonic anhydrase 2 decreases activity EXP malvin results in decreased activity of CA2 protein CTD PMID:28445001 NCBI chr 8:85,464,007...85,481,493
Ensembl chr 8:85,463,968...85,481,493 		JBrowse link
monotropein term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IKBKB inhibitor of nuclear factor kappa B kinase subunit beta multiple interactions ISO monotropein inhibits the reaction [Lipopolysaccharides results in increased activity of IKBKB protein] CTD PMID:23261679 NCBI chr 8:42,271,302...42,332,460
Ensembl chr 8:42,271,302...42,332,460 		JBrowse link
G IL1B interleukin 1 beta multiple interactions ISO monotropein inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; monotropein inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B protein] CTD PMID:23261679 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G MPO myeloperoxidase multiple interactions ISO monotropein inhibits the reaction [Dextran Sulfate results in increased activity of MPO protein] CTD PMID:23261679 NCBI chr17:58,269,855...58,280,935
Ensembl chr17:58,269,855...58,280,935 		JBrowse link
G NFKB1 nuclear factor kappa B subunit 1 multiple interactions ISO monotropein inhibits the reaction [Dextran Sulfate affects the localization of NFKB1 protein]; monotropein inhibits the reaction [Lipopolysaccharides affects the localization of NFKB1 protein] CTD PMID:23261679 NCBI chr 4:102,501,359...102,617,302
Ensembl chr 4:102,501,330...102,617,302 		JBrowse link
G NFKBIA NFKB inhibitor alpha multiple interactions
decreases degradation		 ISO monotropein inhibits the reaction [Dextran Sulfate results in increased phosphorylation of NFKBIA protein]; monotropein inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of NFKBIA protein]
monotropein results in decreased degradation of NFKBIA protein		 CTD PMID:23261679 NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749 		JBrowse link
G NOS2 nitric oxide synthase 2 multiple interactions ISO monotropein inhibits the reaction [Dextran Sulfate results in increased expression of NOS2 protein]; monotropein inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; monotropein inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein] CTD PMID:23261679 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO monotropein inhibits the reaction [Dextran Sulfate results in increased expression of PTGS2 protein]; monotropein inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; monotropein inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein] CTD PMID:23261679 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit multiple interactions ISO monotropein inhibits the reaction [Dextran Sulfate affects the localization of RELA protein]; monotropein inhibits the reaction [Lipopolysaccharides affects the localization of RELA protein] CTD PMID:23261679 NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090 		JBrowse link
G TNF tumor necrosis factor multiple interactions ISO monotropein inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; monotropein inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein] CTD PMID:23261679 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
neoglucobrassicin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HPRT1 hypoxanthine phosphoribosyltransferase 1 increases mutagenesis EXP 1-methoxy-3-indolylmethylglucosinolate metabolite results in increased mutagenesis of HPRT1 gene CTD PMID:20846518 NCBI chr  X:134,460,165...134,500,668
Ensembl chr  X:134,460,165...134,520,513 		JBrowse link
G SULT1A1 sulfotransferase family 1A member 1 increases response to substance EXP SULT1A1 protein results in increased susceptibility to 1-methoxy-3-indolylmethylglucosinolate metabolite CTD PMID:20846518 NCBI chr16:28,605,258...28,623,375
Ensembl chr16:28,605,196...28,610,044 		JBrowse link
neomycin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA1 ATP binding cassette subfamily A member 1 multiple interactions ISO [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in decreased expression of ABCA1 mRNA CTD PMID:36464106 NCBI chr 9:104,781,006...104,928,155
Ensembl chr 9:104,781,006...104,928,155 		JBrowse link
G ABCB1 ATP binding cassette subfamily B member 1 multiple interactions ISO [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of ABCB1A mRNA CTD PMID:36464106 NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323 		JBrowse link
G ABCB11 ATP binding cassette subfamily B member 11 multiple interactions ISO [Cephalothin co-treated with Neomycin] results in increased expression of ABCB11 mRNA; [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of ABCB11 mRNA CTD PMID:24657338 PMID:36464106 NCBI chr 2:168,915,390...169,031,324
Ensembl chr 2:168,915,498...169,031,324 		JBrowse link
G ABCC2 ATP binding cassette subfamily C member 2 multiple interactions ISO [Cephalothin co-treated with Neomycin] results in increased expression of ABCC2 mRNA; [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of ABCC2 mRNA]; [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of ABCC2 mRNA CTD PMID:24657338 PMID:36464106 NCBI chr10:99,782,640...99,852,594
Ensembl chr10:99,782,640...99,852,594 		JBrowse link
G ABCC3 ATP binding cassette subfamily C member 3 multiple interactions ISO [Cephalothin co-treated with Neomycin] results in increased expression of ABCC3 mRNA; [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of ABCC3 mRNA CTD PMID:24657338 PMID:36464106 NCBI chr17:50,634,881...50,692,253
Ensembl chr17:50,634,777...50,692,253 		JBrowse link
G ABCG2 ATP binding cassette subfamily G member 2 (JR blood group) multiple interactions ISO [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of ABCG2 mRNA]; [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of ABCG2 mRNA CTD PMID:36464106 NCBI chr 4:88,090,264...88,231,626
Ensembl chr 4:88,090,150...88,231,628 		JBrowse link
G ABCG5 ATP binding cassette subfamily G member 5 multiple interactions ISO [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in decreased expression of ABCG5 mRNA]; [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in decreased expression of ABCG5 mRNA CTD PMID:36464106 NCBI chr 2:43,806,211...43,839,231
Ensembl chr 2:43,812,472...43,838,865 		JBrowse link
G ACACA acetyl-CoA carboxylase alpha multiple interactions ISO [Vancomycin co-treated with Neomycin co-treated with Metronidazole co-treated with elemicin] results in increased expression of ACACA mRNA CTD PMID:34979169 NCBI chr17:37,084,992...37,406,836
Ensembl chr17:37,084,992...37,406,836 		JBrowse link
G ACAT2 acetyl-CoA acetyltransferase 2 multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of ACAT2 protein CTD PMID:30545405 NCBI chr 6:159,762,045...159,779,112
Ensembl chr 6:159,762,045...159,779,112 		JBrowse link
G ACE2 angiotensin converting enzyme 2 multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of ACE2 protein CTD PMID:30545405 NCBI chr  X:15,518,197...15,607,211
Ensembl chr  X:15,494,566...15,607,236 		JBrowse link
G ADA adenosine deaminase decreases activity
multiple interactions		 ISO Neomycin results in decreased activity of ADA protein
Tetrachlorodibenzodioxin inhibits the reaction [Neomycin results in decreased activity of ADA protein]		 CTD PMID:7853360 NCBI chr20:44,619,522...44,651,699
Ensembl chr20:44,584,896...44,652,252 		JBrowse link
G ADIPOQ adiponectin, C1Q and collagen domain containing multiple interactions ISO [Vancomycin co-treated with Neomycin co-treated with Metronidazole co-treated with elemicin] results in increased expression of ADIPOQ mRNA CTD PMID:34979169 NCBI chr 3:186,842,710...186,858,463
Ensembl chr 3:186,842,704...186,858,463 		JBrowse link
G AHSG alpha 2-HS glycoprotein multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of AHSG protein CTD PMID:30545405 NCBI chr 3:186,613,060...186,621,318
Ensembl chr 3:186,613,060...186,621,318 		JBrowse link
G ALDOA aldolase, fructose-bisphosphate A multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of ALDOA protein CTD PMID:30545405 NCBI chr16:30,064,279...30,070,420
Ensembl chr16:30,064,164...30,070,457 		JBrowse link
G ALDOB aldolase, fructose-bisphosphate B multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of ALDOB protein CTD PMID:30545405 NCBI chr 9:101,420,560...101,435,774
Ensembl chr 9:101,420,560...101,449,664 		JBrowse link
G APAF1 apoptotic peptidase activating factor 1 multiple interactions
increases expression		 ISO peoniflorin inhibits the reaction [Neomycin results in increased expression of APAF1 mRNA] CTD PMID:29292089 NCBI chr12:98,645,290...98,735,433
Ensembl chr12:98,645,149...98,735,433 		JBrowse link
G ARG2 arginase 2 multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of ARG2 protein CTD PMID:30545405 NCBI chr14:67,619,920...67,651,708
Ensembl chr14:67,619,920...67,651,708 		JBrowse link
G ARPC3 actin related protein 2/3 complex subunit 3 multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of ARPC3 protein CTD PMID:30545405 NCBI chr12:110,434,823...110,450,337
Ensembl chr12:110,434,823...110,450,422 		JBrowse link
G ASAH1 N-acylsphingosine amidohydrolase 1 multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of ASAH1 protein CTD PMID:30545405 NCBI chr 8:18,055,992...18,084,961
Ensembl chr 8:18,055,992...18,084,998 		JBrowse link
G ATP1A1 ATPase Na+/K+ transporting subunit alpha 1 multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of ATP1A1 protein CTD PMID:30545405 NCBI chr 1:116,373,244...116,404,774
Ensembl chr 1:116,372,668...116,410,261 		JBrowse link
G ATP2A3 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of ATP2A3 protein CTD PMID:30545405 NCBI chr17:3,923,873...3,964,437
Ensembl chr17:3,923,870...3,964,464 		JBrowse link
G ATP5MF ATP synthase membrane subunit f multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of ATP5MF protein CTD PMID:30545405 NCBI chr 7:99,458,195...99,466,167
Ensembl chr 7:99,448,475...99,466,186 		JBrowse link
G ATP5PD ATP synthase peripheral stalk subunit d multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of ATP5PD protein CTD PMID:30545405 NCBI chr17:75,038,863...75,046,969
Ensembl chr17:75,038,863...75,046,985 		JBrowse link
G ATP5PF ATP synthase peripheral stalk subunit F6 multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of ATP5PF protein CTD PMID:30545405 NCBI chr21:25,724,500...25,735,653
Ensembl chr21:25,716,503...25,735,673 		JBrowse link
G B3GALT5 beta-1,3-galactosyltransferase 5 multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of B3GALT5 protein CTD PMID:30545405 NCBI chr21:39,612,940...39,673,137
Ensembl chr21:39,556,442...39,673,137 		JBrowse link
G BAX BCL2 associated X, apoptosis regulator increases expression
multiple interactions		 ISO Neomycin results in increased expression of BAX mRNA
peoniflorin inhibits the reaction [Neomycin results in increased expression of BAX mRNA]		 CTD PMID:29292089 NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798 		JBrowse link
G BCAT1 branched chain amino acid transaminase 1 decreases expression ISO Neomycin results in decreased expression of BCAT1 mRNA CTD PMID:30626089 NCBI chr12:24,810,024...24,949,340
Ensembl chr12:24,810,024...24,949,101 		JBrowse link
G BCL2 BCL2 apoptosis regulator decreases expression
multiple interactions		 ISO Neomycin results in decreased expression of BCL2 mRNA; Neomycin results in decreased expression of BCL2 protein
peoniflorin inhibits the reaction [Neomycin results in decreased expression of BCL2 mRNA]; peoniflorin inhibits the reaction [Neomycin results in decreased expression of BCL2 protein]		 CTD PMID:29292089 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128 		JBrowse link
G CASP3 caspase 3 multiple interactions
increases expression
affects cleavage		 ISO BIX 01294 affects the reaction [Neomycin affects the cleavage of CASP3 protein]; peoniflorin inhibits the reaction [Neomycin results in increased expression of CASP3 mRNA]; peoniflorin inhibits the reaction [Neomycin results in increased expression of CASP3 protein modified form]
Neomycin results in increased expression of CASP3 mRNA; Neomycin results in increased expression of CASP3 protein modified form		 CTD PMID:23429292 PMID:29292089 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062 		JBrowse link
G CASP9 caspase 9 multiple interactions
increases expression		 ISO peoniflorin inhibits the reaction [Neomycin results in increased expression of CASP9 mRNA]; peoniflorin inhibits the reaction [Neomycin results in increased expression of CASP9 protein modified form]
Neomycin results in increased expression of CASP9 mRNA; Neomycin results in increased expression of CASP9 protein modified form		 CTD PMID:29292089 NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534 		JBrowse link
G CASR calcium sensing receptor multiple interactions EXP
ISO		 CASR protein promotes the reaction [Neomycin results in increased phosphorylation of and results in increased activity of MAPK1 protein]; CASR protein promotes the reaction [Neomycin results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Neomycin binds to and results in increased activity of CASR protein
[Neomycin binds to and results in increased activity of CASR protein] which results in increased abundance of Calcium; [Neomycin binds to and results in increased activity of CASR protein] which results in increased abundance of Inositol Phosphates; Neomycin binds to and results in increased activity of CASR protein		 CTD PMID:10231437 PMID:17537980 NCBI chr 3:122,183,668...122,291,629
Ensembl chr 3:122,183,668...122,291,629 		JBrowse link
G CCNG2 cyclin G2 increases expression ISO Neomycin results in increased expression of CCNG2 mRNA CTD PMID:30626089 NCBI chr 4:77,157,207...77,170,060
Ensembl chr 4:77,157,207...77,433,388 		JBrowse link
G CD86 CD86 molecule increases expression EXP Neomycin results in increased expression of CD86 protein CTD PMID:19665512 NCBI chr 3:122,055,362...122,121,136
Ensembl chr 3:122,055,362...122,121,139 		JBrowse link
G CDH1 cadherin 1 decreases expression ISO Neomycin results in decreased expression of CDH1 protein CTD PMID:15953529 NCBI chr16:68,737,292...68,835,537
Ensembl chr16:68,737,292...68,835,537 		JBrowse link
G CLCA4 chloride channel accessory 4 multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of CLCA4 protein CTD PMID:30545405 NCBI chr 1:86,547,078...86,580,754
Ensembl chr 1:86,547,078...86,580,754 		JBrowse link
G CLDN5 claudin 5 multiple interactions ISO [Neomycin co-treated with Metronidazole co-treated with Ampicillin co-treated with Vancomycin] inhibits the reaction [Methamphetamine results in decreased expression of CLDN5 mRNA]; [Neomycin co-treated with Metronidazole co-treated with Ampicillin co-treated with Vancomycin] inhibits the reaction [Methamphetamine results in decreased expression of CLDN5 protein] CTD PMID:35390362 NCBI chr22:19,523,024...19,525,337
Ensembl chr22:19,523,024...19,527,545 		JBrowse link
G CLDN7 claudin 7 multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of CLDN7 protein CTD PMID:30545405 NCBI chr17:7,259,903...7,263,213
Ensembl chr17:7,259,903...7,263,983 		JBrowse link
G CMBL carboxymethylenebutenolidase homolog multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of CMBL protein CTD PMID:30545405 NCBI chr 5:10,277,595...10,307,902
Ensembl chr 5:10,275,875...10,307,902 		JBrowse link
G CNDP2 carnosine dipeptidase 2 multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of CNDP2 protein CTD PMID:30545405 NCBI chr18:74,496,363...74,523,454
Ensembl chr18:74,495,816...74,523,454 		JBrowse link
G COX5A cytochrome c oxidase subunit 5A multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of COX5A protein CTD PMID:30545405 NCBI chr15:74,919,791...74,938,073
Ensembl chr15:74,919,791...74,938,083 		JBrowse link
G COX6B1 cytochrome c oxidase subunit 6B1 multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of COX6B1 protein CTD PMID:30545405 NCBI chr19:35,648,323...35,658,782
Ensembl chr19:35,648,323...35,658,782 		JBrowse link
G COX7A2 cytochrome c oxidase subunit 7A2 multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of COX7A2 protein CTD PMID:30545405 NCBI chr 6:75,237,675...75,250,298
Ensembl chr 6:75,237,675...75,250,323 		JBrowse link
G CSF2 colony stimulating factor 2 multiple interactions ISO [Ampicillin co-treated with Vancomycin co-treated with Neomycin co-treated with Metronidazole] inhibits the reaction [Dextran Sulfate results in increased expression of CSF2 protein]; [Ampicillin co-treated with Vancomycin co-treated with Neomycin co-treated with Metronidazole] results in decreased expression of CSF2 protein CTD PMID:31442584 NCBI chr 5:132,073,789...132,076,170
Ensembl chr 5:132,073,789...132,076,170 		JBrowse link
G CTH cystathionine gamma-lyase decreases expression
multiple interactions		 ISO Neomycin results in decreased expression of CTH mRNA
Plant Oils inhibits the reaction [Neomycin results in decreased expression of CTH mRNA]		 CTD PMID:30626089 NCBI chr 1:70,411,268...70,439,851
Ensembl chr 1:70,411,218...70,439,851 		JBrowse link
G CTSA cathepsin A multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of CTSA protein CTD PMID:30545405 NCBI chr20:45,891,335...45,898,820
Ensembl chr20:45,890,144...45,898,949 		JBrowse link
G CXCL9 C-X-C motif chemokine ligand 9 multiple interactions ISO [Vancomycin co-treated with Neomycin co-treated with Cilastatin, Imipenem Drug Combination] inhibits the reaction [Doxorubicin results in increased expression of CXCL9 mRNA]; [Vancomycin co-treated with Neomycin co-treated with Cilastatin, Imipenem Drug Combination] inhibits the reaction [Nanotubes, Carbon promotes the reaction [Doxorubicin results in increased expression of CXCL9 mRNA]] CTD PMID:32068018 NCBI chr 4:76,001,275...76,007,509
Ensembl chr 4:76,001,275...76,007,509 		JBrowse link
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of CYP1A2 mRNA CTD PMID:30545405 NCBI chr15:74,748,845...74,756,607
Ensembl chr15:74,748,845...74,756,607 		JBrowse link
G CYP27A1 cytochrome P450 family 27 subfamily A member 1 multiple interactions ISO [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in decreased expression of CYP27A1 mRNA]; [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in decreased expression of CYP27A1 mRNA CTD PMID:36464106 NCBI chr 2:218,782,147...218,815,293
Ensembl chr 2:218,781,749...218,815,293 		JBrowse link
G CYP2C18 cytochrome P450 family 2 subfamily C member 18 multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of CYP2C11 mRNA CTD PMID:30545405 NCBI chr10:94,683,729...94,736,190
Ensembl chr10:94,683,729...94,736,190 		JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of CYP2E1 mRNA CTD PMID:30545405 NCBI chr10:133,527,363...133,539,123
Ensembl chr10:133,520,406...133,561,220 		JBrowse link
G CYP3A4 cytochrome P450 family 3 subfamily A member 4 multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of CYP3A2 mRNA CTD PMID:30545405 NCBI chr 7:99,756,967...99,784,184
Ensembl chr 7:99,756,960...99,784,248 		JBrowse link
G CYP7A1 cytochrome P450 family 7 subfamily A member 1 multiple interactions ISO [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in decreased expression of CYP7A1 mRNA]; [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in decreased expression of CYP7A1 mRNA CTD PMID:36464106 NCBI chr 8:58,490,178...58,500,163
Ensembl chr 8:58,490,178...58,500,163 		JBrowse link
G CYP7B1 cytochrome P450 family 7 subfamily B member 1 multiple interactions ISO [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in decreased expression of CYP7B1 mRNA CTD PMID:36464106 NCBI chr 8:64,586,575...64,798,737
Ensembl chr 8:64,587,763...64,798,737 		JBrowse link
G CYP8B1 cytochrome P450 family 8 subfamily B member 1 multiple interactions ISO [Cephalothin co-treated with Neomycin] results in decreased expression of CYP8B1 mRNA; [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in decreased expression of CYP8B1 mRNA]; [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in decreased expression of CYP8B1 mRNA CTD PMID:24657338 PMID:36464106 NCBI chr 3:42,872,192...42,875,879
Ensembl chr 3:42,856,005...42,875,898 		JBrowse link
G EPCAM epithelial cell adhesion molecule multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of EPCAM protein CTD PMID:30545405 NCBI chr 2:47,369,311...47,387,020
Ensembl chr 2:47,345,158...47,387,601 		JBrowse link
G ETFA electron transfer flavoprotein subunit alpha multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of ETFA protein CTD PMID:30545405 NCBI chr15:76,215,353...76,311,469
Ensembl chr15:76,188,555...76,311,730 		JBrowse link
G EZR ezrin multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of EZR protein CTD PMID:30545405 NCBI chr 6:158,765,748...158,819,368
Ensembl chr 6:158,765,741...158,819,368 		JBrowse link
G FASN fatty acid synthase multiple interactions ISO [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of FASN mRNA]; [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of FASN mRNA; [Vancomycin co-treated with Neomycin co-treated with Metronidazole] inhibits the reaction [elemicin results in increased expression of FASN mRNA] CTD PMID:34979169 PMID:36464106 NCBI chr17:82,078,338...82,098,236
Ensembl chr17:82,078,338...82,098,294 		JBrowse link
G FGF19 fibroblast growth factor 19 multiple interactions ISO [Cephalothin co-treated with Neomycin] results in increased expression of FGF15 mRNA CTD PMID:24657338 NCBI chr11:69,698,238...69,704,022
Ensembl chr11:69,698,238...69,704,022 		JBrowse link
G FOXO1 forkhead box O1 increases expression
multiple interactions		 ISO Neomycin results in increased expression of FOXO1 mRNA
Plant Oils inhibits the reaction [Neomycin results in increased expression of FOXO1 mRNA]		 CTD PMID:30626089 NCBI chr13:40,555,667...40,666,641
Ensembl chr13:40,555,667...40,666,641 		JBrowse link
G GADD45G growth arrest and DNA damage inducible gamma increases expression
multiple interactions		 ISO Neomycin results in increased expression of GADD45G mRNA
Plant Oils inhibits the reaction [Neomycin results in increased expression of GADD45G mRNA]		 CTD PMID:30626089 NCBI chr 9:89,605,012...89,606,555
Ensembl chr 9:89,605,012...89,606,555 		JBrowse link
G GCLM glutamate-cysteine ligase modifier subunit multiple interactions ISO [Vancomycin co-treated with Neomycin co-treated with Metronidazole] promotes the reaction [Zinc Oxide analog results in increased expression of GCLM protein] CTD PMID:36535435 NCBI chr 1:93,885,199...93,909,430
Ensembl chr 1:93,885,199...93,909,456 		JBrowse link
G GFPT2 glutamine-fructose-6-phosphate transaminase 2 multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of GFPT2 protein CTD PMID:30545405 NCBI chr 5:180,300,698...180,353,336
Ensembl chr 5:180,300,698...180,353,336 		JBrowse link
G GIPC2 GIPC PDZ domain containing family member 2 multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of GIPC2 protein CTD PMID:30545405 NCBI chr 1:78,044,970...78,138,444
Ensembl chr 1:77,979,542...78,138,444 		JBrowse link
G GNG12 G protein subunit gamma 12 multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of GNG12 protein CTD PMID:30545405 NCBI chr 1:67,701,475...67,833,467
Ensembl chr 1:67,701,475...67,833,467 		JBrowse link
G GPT glutamic--pyruvic transaminase multiple interactions ISO [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased activity of GPT protein]; [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased activity of GPT protein; [Vancomycin co-treated with Neomycin co-treated with Metronidazole] inhibits the reaction [elemicin results in increased activity of GPT protein] CTD PMID:34979169 PMID:36464106 NCBI chr 8:144,503,068...144,507,172
Ensembl chr 8:144,502,973...144,507,174 		JBrowse link
G GPT2 glutamic--pyruvic transaminase 2 decreases expression ISO Neomycin results in decreased expression of GPT2 mRNA CTD PMID:30626089 NCBI chr16:46,884,362...46,931,289
Ensembl chr16:46,884,362...46,931,289 		JBrowse link
G GPX1 glutathione peroxidase 1 multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of GPX1 protein CTD PMID:30545405 NCBI chr 3:49,357,176...49,358,353
Ensembl chr 3:49,357,174...49,358,605 		JBrowse link
G GSTM2 glutathione S-transferase mu 2 multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of GSTM2 mRNA CTD PMID:30545405 NCBI chr 1:109,668,057...109,683,997
Ensembl chr 1:109,668,022...109,709,551 		JBrowse link
G HEXB hexosaminidase subunit beta multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of HEXB protein CTD PMID:30545405 NCBI chr 5:74,640,023...74,721,288
Ensembl chr 5:74,640,023...74,722,647 		JBrowse link
G HLA-DMB major histocompatibility complex, class II, DM beta multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of RT1-DMB protein CTD PMID:30545405 NCBI chr 6:32,934,636...32,941,028
Ensembl chr 6:32,934,629...32,941,028 		JBrowse link
G HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase multiple interactions ISO [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of HMGCR mRNA]; [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of HMGCR mRNA CTD PMID:36464106 NCBI chr 5:75,336,529...75,362,116
Ensembl chr 5:75,336,329...75,364,001 		JBrowse link
G HMOX1 heme oxygenase 1 multiple interactions ISO [Vancomycin co-treated with Neomycin co-treated with Metronidazole] promotes the reaction [Zinc Oxide analog results in increased expression of HMOX1 protein] CTD PMID:36535435 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214 		JBrowse link
G HNRNPH2 heterogeneous nuclear ribonucleoprotein H2 multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of HNRNPH2 protein CTD PMID:30545405 NCBI chr  X:101,408,222...101,414,133
Ensembl chr  X:101,408,222...101,414,133 		JBrowse link
G HP haptoglobin multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of HP protein CTD PMID:30545405 NCBI chr16:72,054,505...72,061,055
Ensembl chr16:72,054,505...72,061,055 		JBrowse link
G HSPD1 heat shock protein family D (Hsp60) member 1 multiple interactions ISO Neomycin inhibits the reaction [Adenosine Triphosphate results in increased expression of HSPD1 protein] CTD PMID:16178011 NCBI chr 2:197,486,584...197,500,274
Ensembl chr 2:197,486,584...197,516,737 		JBrowse link
G HTR4 5-hydroxytryptamine receptor 4 multiple interactions ISO [Vancomycin co-treated with Neomycin co-treated with Metronidazole] promotes the reaction [Zinc Oxide results in increased expression of HTR4 mRNA]; [Vancomycin co-treated with Neomycin co-treated with Metronidazole] results in increased expression of HTR4 mRNA CTD PMID:36535435 NCBI chr 5:148,451,032...148,654,527
Ensembl chr 5:148,446,042...148,677,235 		JBrowse link
G IL18 interleukin 18 multiple interactions ISO [Neomycin co-treated with Metronidazole co-treated with Ampicillin co-treated with Vancomycin] inhibits the reaction [Methamphetamine results in increased secretion of IL18 protein] CTD PMID:35390362 NCBI chr11:112,143,260...112,164,094
Ensembl chr11:112,143,253...112,164,096 		JBrowse link
G IL1B interleukin 1 beta multiple interactions ISO [Neomycin co-treated with Metronidazole co-treated with Ampicillin co-treated with Vancomycin] inhibits the reaction [Methamphetamine results in increased expression of and results in increased secretion of IL1B protein]; [Neomycin co-treated with Metronidazole co-treated with Ampicillin co-treated with Vancomycin] inhibits the reaction [Methamphetamine results in increased expression of IL1B mRNA]; [Vancomycin co-treated with Neomycin co-treated with Cilastatin, Imipenem Drug Combination] inhibits the reaction [Doxorubicin results in increased expression of IL1B protein]; [Vancomycin co-treated with Neomycin co-treated with Cilastatin, Imipenem Drug Combination] inhibits the reaction [Nanotubes, Carbon promotes the reaction [Doxorubicin results in increased expression of IL1B protein]] CTD PMID:32068018 PMID:35390362 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL6 interleukin 6 multiple interactions ISO [Ampicillin co-treated with Vancomycin co-treated with Neomycin co-treated with Metronidazole] inhibits the reaction [Dextran Sulfate results in increased expression of IL6 protein]; [Ampicillin co-treated with Vancomycin co-treated with Neomycin co-treated with Metronidazole] results in decreased expression of IL6 protein; Dextran Sulfate inhibits the reaction [[Ampicillin co-treated with Vancomycin co-treated with Neomycin co-treated with Metronidazole] results in decreased expression of IL6 protein] CTD PMID:31442584 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G INHBA inhibin subunit beta A increases expression ISO Neomycin results in increased expression of INHBA mRNA CTD PMID:30626089 NCBI chr 7:41,685,114...41,705,406
Ensembl chr 7:41,667,168...41,705,834 		JBrowse link
G INS insulin multiple interactions ISO Neomycin inhibits the reaction [INS protein results in increased uptake of cobaltous chloride] CTD PMID:14622148 NCBI chr11:2,159,779...2,161,209
Ensembl chr11:2,159,779...2,161,221 		JBrowse link
G IRS2 insulin receptor substrate 2 increases expression ISO Neomycin results in increased expression of IRS2 mRNA CTD PMID:30626089 NCBI chr13:109,752,695...109,786,583
Ensembl chr13:109,752,695...109,786,583 		JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression		 ISO 3,9-bis((ethylthio)methyl)-K-252a inhibits the reaction [Neomycin results in increased expression of JUN protein modified form] CTD PMID:10627579 NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,776,845...58,784,048 		JBrowse link
G KLF2 KLF transcription factor 2 increases expression ISO Neomycin results in increased expression of KLF2 mRNA CTD PMID:30626089 NCBI chr19:16,324,826...16,328,685
Ensembl chr19:16,324,826...16,328,685 		JBrowse link
G KRT16 keratin 16 multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of KRT16 protein CTD PMID:30545405 NCBI chr17:41,609,778...41,612,767
Ensembl chr17:41,609,778...41,615,899 		JBrowse link
G LDLR low density lipoprotein receptor multiple interactions ISO [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of LDLR mRNA]; [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of LDLR mRNA CTD PMID:36464106 NCBI chr19:11,089,463...11,133,820
Ensembl chr19:11,089,418...11,133,820 		JBrowse link
G LEP leptin multiple interactions ISO [Vancomycin co-treated with Neomycin co-treated with Metronidazole co-treated with elemicin] results in increased expression of LEP mRNA CTD PMID:34979169 NCBI chr 7:128,241,278...128,257,629
Ensembl chr 7:128,241,278...128,257,629 		JBrowse link
G LPIN1 lipin 1 multiple interactions ISO [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of LPIN1 mRNA]; [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of LPIN1 mRNA CTD PMID:36464106 NCBI chr 2:11,677,544...11,827,409
Ensembl chr 2:11,677,595...11,827,409 		JBrowse link
G LYZ lysozyme multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of LYZ2 protein CTD PMID:30545405 NCBI chr12:69,348,381...69,354,234
Ensembl chr12:69,348,381...69,354,234 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 multiple interactions
increases expression		 EXP
ISO		 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Neomycin results in increased phosphorylation of and results in increased activity of MAPK1 protein]; CASR protein promotes the reaction [Neomycin results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Neomycin results in increased phosphorylation of and results in increased activity of MAPK1 protein
Neomycin results in increased expression of MAPK1 protein modified form
peoniflorin inhibits the reaction [Neomycin results in increased expression of MAPK1 protein modified form]		 CTD PMID:17537980 PMID:29292089 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 multiple interactions
increases expression		 EXP
ISO		 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Neomycin results in increased phosphorylation of and results in increased activity of MAPK3 protein]; CASR protein promotes the reaction [Neomycin results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Neomycin results in increased phosphorylation of and results in increased activity of MAPK3 protein
[Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of MAPK3 protein
Neomycin results in increased expression of MAPK3 protein modified form
peoniflorin inhibits the reaction [Neomycin results in increased expression of MAPK3 protein modified form]		 CTD PMID:17537980 PMID:29292089 PMID:30545405 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506 		JBrowse link
G MLXIP MLX interacting protein multiple interactions ISO [Vancomycin co-treated with Neomycin co-treated with Metronidazole] inhibits the reaction [elemicin results in increased expression of MLXIP mRNA] CTD PMID:34979169 NCBI chr12:122,078,756...122,147,344
Ensembl chr12:122,078,756...122,147,344 		JBrowse link
G MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase decreases expression
multiple interactions		 ISO Neomycin results in decreased expression of MTHFD2 mRNA
Plant Oils inhibits the reaction [Neomycin results in decreased expression of MTHFD2 mRNA]		 CTD PMID:30626089 NCBI chr 2:74,198,615...74,217,565
Ensembl chr 2:74,186,172...74,217,565 		JBrowse link
G MYD88 MYD88 innate immune signal transduction adaptor multiple interactions ISO [Neomycin co-treated with Metronidazole co-treated with Ampicillin co-treated with Vancomycin] inhibits the reaction [Methamphetamine results in increased expression of MYD88 mRNA]; [Neomycin co-treated with Metronidazole co-treated with Ampicillin co-treated with Vancomycin] inhibits the reaction [Methamphetamine results in increased expression of MYD88 protein] CTD PMID:35390362 NCBI chr 3:38,138,661...38,143,022
Ensembl chr 3:38,138,552...38,143,024 		JBrowse link
G MYH14 myosin heavy chain 14 multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of MYH14 protein CTD PMID:30545405 NCBI chr19:50,203,622...50,310,540
Ensembl chr19:50,188,186...50,310,542 		JBrowse link
G NDUFA13 NADH:ubiquinone oxidoreductase subunit A13 multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of NDUFA13 protein CTD PMID:30545405 NCBI chr19:19,516,225...19,528,198
Ensembl chr19:19,515,736...19,529,054 		JBrowse link
G NDUFAB1 NADH:ubiquinone oxidoreductase subunit AB1 multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of NDUFAB1 protein CTD PMID:30545405 NCBI chr16:23,581,014...23,596,316
Ensembl chr16:23,581,014...23,596,316 		JBrowse link
G NOG noggin increases expression ISO Neomycin results in increased expression of NOG mRNA CTD PMID:30626089 NCBI chr17:56,593,699...56,595,611
Ensembl chr17:56,593,699...56,595,611 		JBrowse link
G NOS2 nitric oxide synthase 2 multiple interactions ISO [Vancomycin co-treated with Neomycin co-treated with Cilastatin, Imipenem Drug Combination] inhibits the reaction [Doxorubicin results in increased expression of NOS2 mRNA]; [Vancomycin co-treated with Neomycin co-treated with Cilastatin, Imipenem Drug Combination] inhibits the reaction [Nanotubes, Carbon promotes the reaction [Doxorubicin results in increased expression of NOS2 mRNA]] CTD PMID:32068018 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529 		JBrowse link
G NPC1L1 NPC1 like intracellular cholesterol transporter 1 multiple interactions ISO [Cephalothin co-treated with Neomycin] results in increased expression of NPC1L1 mRNA CTD PMID:24657338 NCBI chr 7:44,512,535...44,541,330
Ensembl chr 7:44,512,535...44,541,330 		JBrowse link
G NPC2 NPC intracellular cholesterol transporter 2 multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of NPC2 protein CTD PMID:30545405 NCBI chr14:74,479,935...74,493,512
Ensembl chr14:74,476,192...74,494,177 		JBrowse link
G NR5A2 nuclear receptor subfamily 5 group A member 2 multiple interactions ISO [Cephalothin co-treated with Neomycin] results in increased expression of NR5A2 mRNA CTD PMID:24657338 NCBI chr 1:200,027,710...200,177,415
Ensembl chr 1:200,027,614...200,177,420 		JBrowse link
G OCLN occludin multiple interactions ISO [Neomycin co-treated with Metronidazole co-treated with Ampicillin co-treated with Vancomycin] inhibits the reaction [Methamphetamine results in decreased expression of OCLN mRNA]; [Neomycin co-treated with Metronidazole co-treated with Ampicillin co-treated with Vancomycin] inhibits the reaction [Methamphetamine results in decreased expression of OCLN protein] CTD PMID:35390362 NCBI chr 5:69,492,547...69,558,104
Ensembl chr 5:69,492,292...69,558,104 		JBrowse link
G PFN1 profilin 1 multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of PFN1 protein CTD PMID:30545405 NCBI chr17:4,945,652...4,948,530
Ensembl chr17:4,945,652...4,949,061 		JBrowse link
G PGAM1 phosphoglycerate mutase 1 multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of PGAM1 protein CTD PMID:30545405 NCBI chr10:97,426,191...97,433,444
Ensembl chr10:97,426,191...97,433,444 		JBrowse link
G PMM2 phosphomannomutase 2 multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of PMM2 protein CTD PMID:30545405 NCBI chr16:8,797,839...8,849,325
Ensembl chr16:8,788,823...8,862,534 		JBrowse link
G PPP1CA protein phosphatase 1 catalytic subunit alpha multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of PPP1CA protein CTD PMID:30545405 NCBI chr11:67,398,183...67,401,858
Ensembl chr11:67,398,181...67,421,183 		JBrowse link
G PPP1CB protein phosphatase 1 catalytic subunit beta multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of PPP1CB protein CTD PMID:30545405 NCBI chr 2:28,751,604...28,802,940
Ensembl chr 2:28,751,640...28,802,940 		JBrowse link
G PPP1CC protein phosphatase 1 catalytic subunit gamma multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of PPP1CC protein CTD PMID:30545405 NCBI chr12:110,708,376...110,742,891
Ensembl chr12:110,719,680...110,742,939 		JBrowse link
G PSAT1 phosphoserine aminotransferase 1 decreases expression
multiple interactions		 ISO Neomycin results in decreased expression of PSAT1 mRNA
Plant Oils inhibits the reaction [Neomycin results in decreased expression of PSAT1 mRNA]		 CTD PMID:30626089 NCBI chr 9:78,297,125...78,330,093
Ensembl chr 9:78,297,125...78,330,093 		JBrowse link
G PSMA3 proteasome 20S subunit alpha 3 multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of PSMA3 protein CTD PMID:30545405 NCBI chr14:58,244,843...58,272,004
Ensembl chr14:58,244,843...58,272,012 		JBrowse link
G PSPH phosphoserine phosphatase decreases expression
multiple interactions		 ISO Neomycin results in decreased expression of PSPH mRNA
Plant Oils inhibits the reaction [Neomycin results in decreased expression of PSPH mRNA]		 CTD PMID:30626089 NCBI chr 7:56,011,064...56,051,444
Ensembl chr 7:56,011,051...56,051,604 		JBrowse link
G RALB RAS like proto-oncogene B multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of RALB protein CTD PMID:30545405 NCBI chr 2:120,240,070...120,294,710
Ensembl chr 2:120,240,064...120,294,710 		JBrowse link
G RAN RAN, member RAS oncogene family multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of RAN protein CTD PMID:30545405 NCBI chr12:130,872,066...130,877,678
Ensembl chr12:130,872,037...130,877,678 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit multiple interactions ISO [Neomycin co-treated with Metronidazole co-treated with Ampicillin co-treated with Vancomycin] inhibits the reaction [Methamphetamine results in increased expression of RELA mRNA]; [Neomycin co-treated with Metronidazole co-treated with Ampicillin co-treated with Vancomycin] inhibits the reaction [Methamphetamine results in increased expression of RELA protein] CTD PMID:35390362 NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090 		JBrowse link
G RIDA reactive intermediate imine deaminase A homolog multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of RIDA protein CTD PMID:30545405 NCBI chr 8:98,102,344...98,117,171
Ensembl chr 8:98,102,344...98,117,171 		JBrowse link
G RPL30 ribosomal protein L30 multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of RPL30 protein CTD PMID:30545405 NCBI chr 8:98,041,721...98,045,545
Ensembl chr 8:98,024,851...98,046,469 		JBrowse link
G RPN2 ribophorin II multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of RPN2 protein CTD PMID:30545405 NCBI chr20:37,179,330...37,241,619
Ensembl chr20:37,178,410...37,241,619 		JBrowse link
G RPS23 ribosomal protein S23 multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of RPS23 protein CTD PMID:30545405 NCBI chr 5:82,273,320...82,278,354
Ensembl chr 5:82,273,320...82,278,396 		JBrowse link
G RPS27L ribosomal protein S27 like multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of RPS27L protein CTD PMID:30545405 NCBI chr15:63,148,249...63,157,477
Ensembl chr15:63,125,872...63,158,021 		JBrowse link
G RPS6KB1 ribosomal protein S6 kinase B1 affects phosphorylation ISO Neomycin affects the phosphorylation of RPS6KB1 protein CTD PMID:16537399 NCBI chr17:59,893,121...59,950,574
Ensembl chr17:59,893,046...59,950,574 		JBrowse link
G S100A10 S100 calcium binding protein A10 multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of S100A10 protein CTD PMID:30545405 NCBI chr 1:151,982,915...151,993,859
Ensembl chr 1:151,982,915...151,993,859 		JBrowse link
G S100A11 S100 calcium binding protein A11 multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of S100A11 protein CTD PMID:30545405 NCBI chr 1:152,032,506...152,037,004
Ensembl chr 1:152,032,506...152,047,907 		JBrowse link
G SCARB2 scavenger receptor class B member 2 multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of SCARB2 protein CTD PMID:30545405 NCBI chr 4:76,158,737...76,234,532
Ensembl chr 4:76,158,737...76,234,536 		JBrowse link
G SERPINB6 serpin family B member 6 multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of SERPINB6 protein CTD PMID:30545405 NCBI chr 6:2,948,159...2,971,793
Ensembl chr 6:2,948,159...2,972,165 		JBrowse link
G SHMT2 serine hydroxymethyltransferase 2 decreases expression
multiple interactions		 ISO Neomycin results in decreased expression of SHMT2 mRNA
[Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of SHMT2 protein		 CTD PMID:30545405 PMID:30626089 NCBI chr12:57,229,711...57,234,935
Ensembl chr12:57,229,573...57,234,935 		JBrowse link
G SLC10A1 solute carrier family 10 member 1 multiple interactions ISO [Cephalothin co-treated with Neomycin] results in increased expression of SLC10A1 mRNA CTD PMID:24657338 NCBI chr14:69,775,416...69,797,241
Ensembl chr14:69,775,416...69,797,241 		JBrowse link
G SLC22A7 solute carrier family 22 member 7 multiple interactions ISO [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of SLC22A7 mRNA CTD PMID:36464106 NCBI chr 6:43,295,714...43,305,538
Ensembl chr 6:43,295,694...43,305,538 		JBrowse link
G SLC3A1 solute carrier family 3 member 1 multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of SLC3A1 protein CTD PMID:30545405 NCBI chr 2:44,275,480...44,322,437
Ensembl chr 2:44,275,458...44,321,494 		JBrowse link
G SLC51B SLC51 subunit beta multiple interactions ISO [Cephalothin co-treated with Neomycin] results in decreased expression of SLC51B mRNA CTD PMID:24657338 NCBI chr15:65,045,387...65,053,397
Ensembl chr15:65,045,387...65,053,397 		JBrowse link
G SLCO1B3 solute carrier organic anion transporter family member 1B3 multiple interactions ISO [Cephalothin co-treated with Neomycin] results in increased expression of SLCO1B2 mRNA CTD PMID:24657338 NCBI chr12:20,810,705...20,916,911
Ensembl chr12:20,810,702...20,916,911 		JBrowse link
G SMAD6 SMAD family member 6 increases expression ISO Neomycin results in increased expression of SMAD6 mRNA CTD PMID:30626089 NCBI chr15:66,702,236...66,782,849
Ensembl chr15:66,702,236...66,782,849 		JBrowse link
G SMAD9 SMAD family member 9 increases expression ISO Neomycin results in increased expression of SMAD9 mRNA CTD PMID:30626089 NCBI chr13:36,844,831...36,920,854
Ensembl chr13:36,844,831...36,920,887 		JBrowse link
G SMPD2 sphingomyelin phosphodiesterase 2 multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of SMPD2 protein CTD PMID:30545405 NCBI chr 6:109,440,724...109,443,919
Ensembl chr 6:109,440,724...109,443,919 		JBrowse link
G SQLE squalene epoxidase multiple interactions ISO [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of SQLE mRNA CTD PMID:36464106 NCBI chr 8:124,998,505...125,022,283
Ensembl chr 8:124,998,497...125,022,283 		JBrowse link
G SQSTM1 sequestosome 1 multiple interactions ISO [Vancomycin co-treated with Neomycin co-treated with Metronidazole] promotes the reaction [Zinc Oxide analog results in increased expression of SQSTM1 protein] CTD PMID:36535435 NCBI chr 5:179,806,393...179,838,078
Ensembl chr 5:179,806,398...179,838,078 		JBrowse link
G SREBF1 sterol regulatory element binding transcription factor 1 multiple interactions ISO [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of SREBF1 mRNA]; [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of SREBF1 mRNA CTD PMID:36464106 NCBI chr17:17,811,334...17,836,986
Ensembl chr17:17,810,399...17,837,002 		JBrowse link
G SREBF2 sterol regulatory element binding transcription factor 2 multiple interactions ISO [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of SREBF2 mRNA CTD PMID:36464106 NCBI chr22:41,833,105...41,907,305
Ensembl chr22:41,833,105...41,907,306 		JBrowse link
G SST somatostatin multiple interactions ISO [Vancomycin co-treated with Neomycin co-treated with Metronidazole] promotes the reaction [Zinc Oxide results in increased expression of SST mRNA]; [Vancomycin co-treated with Neomycin co-treated with Metronidazole] results in increased expression of SST mRNA CTD PMID:36535435 NCBI chr 3:187,668,912...187,670,394
Ensembl chr 3:187,668,912...187,670,394 		JBrowse link
G SSTR2 somatostatin receptor 2 multiple interactions ISO [Vancomycin co-treated with Neomycin co-treated with Metronidazole] promotes the reaction [Zinc Oxide results in increased expression of SSTR2 mRNA] CTD PMID:36535435 NCBI chr17:73,165,010...73,176,633
Ensembl chr17:73,165,010...73,176,633 		JBrowse link
G TARS1 threonyl-tRNA synthetase 1 multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of TARS1 protein CTD PMID:30545405 NCBI chr 5:33,440,696...33,468,091
Ensembl chr 5:33,440,696...33,468,091 		JBrowse link
G TGFB2 transforming growth factor beta 2 multiple interactions
increases expression		 ISO Plant Oils inhibits the reaction [Neomycin results in increased expression of TGFB2 mRNA] CTD PMID:30626089 NCBI chr 1:218,345,336...218,444,619
Ensembl chr 1:218,345,336...218,444,619 		JBrowse link
G TJP1 tight junction protein 1 multiple interactions ISO [Neomycin co-treated with Metronidazole co-treated with Ampicillin co-treated with Vancomycin] inhibits the reaction [Methamphetamine results in decreased expression of TJP1 mRNA]; [Neomycin co-treated with Metronidazole co-treated with Ampicillin co-treated with Vancomycin] inhibits the reaction [Methamphetamine results in decreased expression of TJP1 protein] CTD PMID:35390362 NCBI chr15:29,699,367...29,969,049
Ensembl chr15:29,699,367...29,968,915 		JBrowse link
G TLR4 toll like receptor 4 multiple interactions ISO [Neomycin co-treated with Metronidazole co-treated with Ampicillin co-treated with Vancomycin] inhibits the reaction [Methamphetamine results in increased expression of TLR4 mRNA]; [Neomycin co-treated with Metronidazole co-treated with Ampicillin co-treated with Vancomycin] inhibits the reaction [Methamphetamine results in increased expression of TLR4 protein]; TLR4 gene mutant form results in decreased susceptibility to [Neomycin co-treated with Metronidazole co-treated with Ampicillin co-treated with Vancomycin] CTD PMID:35390362 NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735 		JBrowse link
G TM9SF2 transmembrane 9 superfamily member 2 multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of TM9SF2 protein CTD PMID:30545405 NCBI chr13:99,501,472...99,564,048
Ensembl chr13:99,446,311...99,564,048 		JBrowse link
G TMED10 transmembrane p24 trafficking protein 10 multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of TMED10 protein CTD PMID:30545405 NCBI chr14:75,131,469...75,176,612
Ensembl chr14:75,131,469...75,176,612 		JBrowse link
G TNF tumor necrosis factor multiple interactions ISO [Ampicillin co-treated with Vancomycin co-treated with Neomycin co-treated with Metronidazole] inhibits the reaction [Dextran Sulfate results in increased expression of TNF protein]; [Ampicillin co-treated with Vancomycin co-treated with Neomycin co-treated with Metronidazole] results in decreased expression of TNF protein; [Neomycin co-treated with Metronidazole co-treated with Ampicillin co-treated with Vancomycin] inhibits the reaction [Methamphetamine results in increased expression of and results in increased secretion of TNF protein]; [Neomycin co-treated with Metronidazole co-treated with Ampicillin co-treated with Vancomycin] inhibits the reaction [Methamphetamine results in increased expression of TNF mRNA]; [Vancomycin co-treated with Neomycin co-treated with Cilastatin, Imipenem Drug Combination] inhibits the reaction [Doxorubicin results in increased expression of TNF protein]; [Vancomycin co-treated with Neomycin co-treated with Cilastatin, Imipenem Drug Combination] inhibits the reaction [Nanotubes, Carbon promotes the reaction [Doxorubicin results in increased expression of TNF protein]]; Dextran Sulfate inhibits the reaction [[Ampicillin co-treated with Vancomycin co-treated with Neomycin co-treated with Metronidazole] results in decreased expression of TNF protein] CTD PMID:31442584 PMID:32068018 PMID:35390362 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TRAF6 TNF receptor associated factor 6 multiple interactions ISO [Neomycin co-treated with Metronidazole co-treated with Ampicillin co-treated with Vancomycin] inhibits the reaction [Methamphetamine results in increased expression of TRAF6 mRNA]; [Neomycin co-treated with Metronidazole co-treated with Ampicillin co-treated with Vancomycin] inhibits the reaction [Methamphetamine results in increased expression of TRAF6 protein] CTD PMID:35390362 NCBI chr11:36,483,769...36,510,272
Ensembl chr11:36,483,769...36,510,272 		JBrowse link
G TUBAL3 tubulin alpha like 3 multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of TUBAL3 protein CTD PMID:30545405 NCBI chr10:5,393,101...5,404,828
Ensembl chr10:5,393,101...5,404,828 		JBrowse link
G TWF1 twinfilin actin binding protein 1 multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of TWF1 protein CTD PMID:30545405 NCBI chr12:43,793,723...43,806,317
Ensembl chr12:43,793,723...43,806,328 		JBrowse link
G TXN thioredoxin multiple interactions ISO [Vancomycin co-treated with Neomycin co-treated with Metronidazole] promotes the reaction [Zinc Oxide analog results in increased expression of TXN1 protein] CTD PMID:36535435 NCBI chr 9:110,243,810...110,256,507
Ensembl chr 9:110,243,810...110,256,507 		JBrowse link
G TXNDC5 thioredoxin domain containing 5 multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of TXNDC5 protein CTD PMID:30545405 NCBI chr 6:7,881,517...7,910,788
Ensembl chr 6:7,881,517...7,910,788 		JBrowse link
G UQCRC1 ubiquinol-cytochrome c reductase core protein 1 multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of UQCRC1 protein CTD PMID:30545405 NCBI chr 3:48,599,002...48,609,646
Ensembl chr 3:48,599,002...48,610,976 		JBrowse link
G UQCRFS1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of UQCRFS1 protein CTD PMID:30545405 NCBI chr19:29,205,320...29,213,151
Ensembl chr19:29,205,320...29,213,151 		JBrowse link
G UQCRH ubiquinol-cytochrome c reductase hinge protein multiple interactions ISO [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of UQCRH protein CTD PMID:30545405 NCBI chr 1:46,303,698...46,316,776
Ensembl chr 1:46,303,698...46,316,776 		JBrowse link
G VDR vitamin D receptor multiple interactions ISO [Cephalothin co-treated with Neomycin] results in increased expression of VDR mRNA CTD PMID:24657338 NCBI chr12:47,841,537...47,904,994
Ensembl chr12:47,841,537...47,943,048 		JBrowse link
norswertianolin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GCLC glutamate-cysteine ligase catalytic subunit increases expression ISO norswertianolin results in increased expression of GCLC mRNA; norswertianolin results in increased expression of GCLC protein CTD PMID:30800665 NCBI chr 6:53,497,341...53,545,101
Ensembl chr 6:53,497,341...53,616,970 		JBrowse link
G HMOX1 heme oxygenase 1 increases expression ISO norswertianolin results in increased expression of HMOX1 mRNA; norswertianolin results in increased expression of HMOX1 protein CTD PMID:30800665 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214 		JBrowse link
notoginsenoside R1 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 multiple interactions
increases expression		 EXP
ISO		 NR1I2 protein promotes the reaction [notoginsenoside R1 results in increased expression of ABCB1 mRNA]
notoginsenoside R1 results in increased expression of ABCB1A mRNA		 CTD PMID:25472953 NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323 		JBrowse link
G ABCB11 ATP binding cassette subfamily B member 11 increases transport ISO
EXP		 ABCB11 protein results in increased transport of notoginsenoside R1 CTD PMID:25297453 NCBI chr 2:168,915,390...169,031,324
Ensembl chr 2:168,915,498...169,031,324 		JBrowse link
G ABCC1 ATP binding cassette subfamily C member 1 (ABCC1 blood group) increases transport EXP ABCC1 protein results in increased transport of notoginsenoside R1 CTD PMID:25297453 NCBI chr16:15,949,143...16,143,053
Ensembl chr16:15,949,138...16,143,257 		JBrowse link
G ABCC2 ATP binding cassette subfamily C member 2 increases transport ISO
EXP		 ABCC2 protein results in increased transport of notoginsenoside R1 CTD PMID:25297453 NCBI chr10:99,782,640...99,852,594
Ensembl chr10:99,782,640...99,852,594 		JBrowse link
G ABCG2 ATP binding cassette subfamily G member 2 (JR blood group) increases transport ISO
EXP		 ABCG2 protein results in increased transport of notoginsenoside R1 CTD PMID:25297453 NCBI chr 4:88,090,264...88,231,626
Ensembl chr 4:88,090,150...88,231,628 		JBrowse link
G AKT1 AKT serine/threonine kinase 1 multiple interactions
increases phosphorylation		 ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [notoginsenoside R1 inhibits the reaction [triethylene glycol dimethacrylate results in decreased phosphorylation of AKT1 protein]]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [notoginsenoside R1 results in increased phosphorylation of AKT1 protein]; notoginsenoside R1 inhibits the reaction [triethylene glycol dimethacrylate results in decreased phosphorylation of AKT1 protein] CTD PMID:33689844 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,759 		JBrowse link
G APOE apolipoprotein E multiple interactions ISO notoginsenoside R1 inhibits the reaction [APOE gene mutant form results in decreased abundance of Glutathione]; notoginsenoside R1 inhibits the reaction [APOE gene mutant form results in decreased expression of MIR20A mRNA]; notoginsenoside R1 inhibits the reaction [APOE gene mutant form results in increased abundance of Cholesterol]; notoginsenoside R1 inhibits the reaction [APOE gene mutant form results in increased abundance of Triglycerides]; notoginsenoside R1 inhibits the reaction [APOE gene mutant form results in increased expression of IFNG protein]; notoginsenoside R1 inhibits the reaction [APOE gene mutant form results in increased expression of IL2 protein]; notoginsenoside R1 inhibits the reaction [APOE gene mutant form results in increased expression of IL6 protein]; notoginsenoside R1 inhibits the reaction [APOE gene mutant form results in increased expression of MIR126A mRNA]; notoginsenoside R1 inhibits the reaction [APOE gene mutant form results in increased expression of MIR21A mRNA]; notoginsenoside R1 inhibits the reaction [APOE gene mutant form results in increased expression of TNF protein] CTD PMID:24933211 NCBI chr19:44,905,796...44,909,393
Ensembl chr19:44,905,791...44,909,393 		JBrowse link
G APP amyloid beta precursor protein multiple interactions ISO notoginsenoside R1 inhibits the reaction [[APP gene mutant form co-treated with PSEN1 gene mutant form] results in increased expression of APP protein modified form]
notoginsenoside R1 inhibits the reaction [APP protein modified form results in decreased expression of BCL2 protein]; notoginsenoside R1 inhibits the reaction [APP protein modified form results in increased cleavage of CASP3 protein]; notoginsenoside R1 inhibits the reaction [APP protein modified form results in increased expression of BAX protein]; notoginsenoside R1 inhibits the reaction [APP protein modified form results in increased phosphorylation of MAPK1 protein]; notoginsenoside R1 inhibits the reaction [APP protein modified form results in increased phosphorylation of MAPK3 protein]; notoginsenoside R1 inhibits the reaction [APP protein modified form results in increased phosphorylation of MAPK8 protein]; notoginsenoside R1 inhibits the reaction [APP protein modified form results in increased phosphorylation of MAPK9 protein]		 CTD PMID:24975829 PMID:25714973 NCBI chr21:25,880,550...26,171,128
Ensembl chr21:25,880,535...26,171,128 		JBrowse link
G ATP5F1D ATP synthase F1 subunit delta multiple interactions ISO 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid inhibits the reaction [notoginsenoside R1 inhibits the reaction [[Oxygen co-treated with [Oxygen deficiency co-treated with Glucose deficiency]] results in decreased expression of ATP5F1D protein]]; notoginsenoside R1 inhibits the reaction [[Oxygen co-treated with [Oxygen deficiency co-treated with Glucose deficiency]] results in decreased expression of ATP5F1D protein] CTD PMID:25305180 NCBI chr19:1,241,751...1,244,825
Ensembl chr19:1,241,746...1,244,825 		JBrowse link
G BAX BCL2 associated X, apoptosis regulator multiple interactions ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [notoginsenoside R1 inhibits the reaction [triethylene glycol dimethacrylate results in increased expression of BAX protein]]; 3-(2,4-dichloro-5-methoxyphenyl)-2-sulfanyl-4(3H)-quinazolinone inhibits the reaction [notoginsenoside R1 inhibits the reaction [triethylene glycol dimethacrylate results in increased expression of BAX protein]]; Cyclosporine inhibits the reaction [notoginsenoside R1 inhibits the reaction [triethylene glycol dimethacrylate results in increased expression of BAX protein]]; notoginsenoside R1 inhibits the reaction [Excitatory Amino Acid Agonists results in increased expression of BAX protein]; notoginsenoside R1 inhibits the reaction [triethylene glycol dimethacrylate results in increased expression of BAX protein]
notoginsenoside R1 inhibits the reaction [[Oxygen co-treated with [Oxygen deficiency co-treated with Glucose deficiency]] results in increased expression of BAX protein]; notoginsenoside R1 inhibits the reaction [APP protein modified form results in increased expression of BAX protein]		 CTD PMID:19224577 PMID:24975829 PMID:25305180 PMID:33689844 NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798 		JBrowse link
G BCL2 BCL2 apoptosis regulator multiple interactions
increases expression		 ISO notoginsenoside R1 inhibits the reaction [Excitatory Amino Acid Agonists results in decreased expression of BCL2 protein]; notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in decreased expression of BCL2 protein]
notoginsenoside R1 results in increased expression of BCL2
15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid inhibits the reaction [notoginsenoside R1 inhibits the reaction [[Oxygen co-treated with [Oxygen deficiency co-treated with Glucose deficiency]] results in decreased expression of BCL2 protein]]; notoginsenoside R1 inhibits the reaction [[Oxygen co-treated with [Oxygen deficiency co-treated with Glucose deficiency]] results in decreased expression of BCL2 protein]; notoginsenoside R1 inhibits the reaction [APP protein modified form results in decreased expression of BCL2 protein]		 CTD PMID:19224577 PMID:20023602 PMID:23170834 PMID:24975829 PMID:25305180 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128 		JBrowse link
G BGLAP bone gamma-carboxyglutamate protein multiple interactions
increases expression		 EXP fulvestrant inhibits the reaction [notoginsenoside R1 results in increased expression of BGLAP mRNA] CTD PMID:26362186 NCBI chr 1:156,242,184...156,243,317
Ensembl chr 1:156,242,184...156,243,317 		JBrowse link
G BID BH3 interacting domain death agonist multiple interactions ISO notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased expression of BID protein modified form] CTD PMID:23170834 NCBI chr22:17,734,138...17,774,665
Ensembl chr22:17,734,138...17,774,770 		JBrowse link
G CASP3 caspase 3 multiple interactions ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [notoginsenoside R1 inhibits the reaction [triethylene glycol dimethacrylate results in increased cleavage of CASP3 protein]]; 3-(2,4-dichloro-5-methoxyphenyl)-2-sulfanyl-4(3H)-quinazolinone inhibits the reaction [notoginsenoside R1 inhibits the reaction [triethylene glycol dimethacrylate results in increased cleavage of CASP3 protein]]; Cyclosporine inhibits the reaction [notoginsenoside R1 inhibits the reaction [triethylene glycol dimethacrylate results in increased cleavage of CASP3 protein]]; notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased activity of CASP3 protein]; notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased expression of CASP3 protein modified form]; notoginsenoside R1 inhibits the reaction [triethylene glycol dimethacrylate results in increased cleavage of CASP3 protein]
15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid inhibits the reaction [notoginsenoside R1 inhibits the reaction [[Oxygen co-treated with [Oxygen deficiency co-treated with Glucose deficiency]] results in increased cleavage of CASP3 protein]]; notoginsenoside R1 inhibits the reaction [[Oxygen co-treated with [Oxygen deficiency co-treated with Glucose deficiency]] results in increased activity of CASP3 protein]; notoginsenoside R1 inhibits the reaction [[Oxygen co-treated with [Oxygen deficiency co-treated with Glucose deficiency]] results in increased cleavage of CASP3 protein]; notoginsenoside R1 inhibits the reaction [APP protein modified form results in increased cleavage of CASP3 protein]; notoginsenoside R1 inhibits the reaction [Hydrogen Peroxide results in increased activity of CASP3 protein]; notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased activity of CASP3 protein]		 CTD PMID:23170834 PMID:24437944 PMID:24720662 PMID:24975829 PMID:25305180 More... NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062 		JBrowse link
G CASP8 caspase 8 multiple interactions ISO notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased activity of CASP8 protein] CTD PMID:23170834 NCBI chr 2:201,233,463...201,287,711
Ensembl chr 2:201,233,443...201,361,836 		JBrowse link
G CASP9 caspase 9 multiple interactions ISO notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased activity of CASP9 protein] CTD PMID:23170834 NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534 		JBrowse link
G CAT catalase multiple interactions ISO notoginsenoside R1 inhibits the reaction [Streptozocin results in decreased activity of CAT protein] CTD PMID:25503068 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060 		JBrowse link
G CCL2 C-C motif chemokine ligand 2 multiple interactions ISO notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased expression of CCL2 mRNA]; notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased expression of CCL2 protein] CTD PMID:23170834 PMID:25472953 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208 		JBrowse link
G CHAT choline O-acetyltransferase increases expression ISO notoginsenoside R1 results in increased expression of CHAT CTD PMID:25714973 NCBI chr10:49,609,095...49,667,942
Ensembl chr10:49,609,095...49,667,942 		JBrowse link
G CHUK component of inhibitor of nuclear factor kappa B kinase complex multiple interactions ISO notoginsenoside R1 inhibits the reaction [Dextran Sulfate results in increased expression of CHUK protein modified form] CTD PMID:25472953 NCBI chr10:100,186,319...100,229,596
Ensembl chr10:100,188,300...100,229,596 		JBrowse link
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 decreases activity ISO notoginsenoside R1 results in decreased activity of CYP1A2 protein CTD PMID:25834921 NCBI chr15:74,748,845...74,756,607
Ensembl chr15:74,748,845...74,756,607 		JBrowse link
G CYP3A4 cytochrome P450 family 3 subfamily A member 4 increases expression EXP notoginsenoside R1 results in increased expression of CYP3A4 mRNA CTD PMID:25472953 NCBI chr 7:99,756,967...99,784,184
Ensembl chr 7:99,756,960...99,784,248 		JBrowse link
G ESR1 estrogen receptor 1 multiple interactions
increases expression		 EXP
ISO		 notoginsenoside R1 results in increased phosphorylation of and results in increased activity of ESR1 protein
notoginsenoside R1 results in increased expression of ESR1; notoginsenoside R1 results in increased expression of ESR1 mRNA; notoginsenoside R1 results in increased expression of ESR1 protein
[1,3-bis(4-hydroxyphenyl)-4-methyl-5-(4-(2-piperidinylethoxy)phenol)-1H-pyrazole results in decreased activity of ESR1 protein] which results in decreased susceptibility to notoginsenoside R1; [notoginsenoside R1 co-treated with Lipopolysaccharides] results in increased expression of ESR1 protein; fulvestrant inhibits the reaction [[notoginsenoside R1 co-treated with Lipopolysaccharides] results in increased expression of ESR1 protein]		 CTD PMID:23170834 PMID:24720662 PMID:25738436 PMID:26362186 NCBI chr 6:151,656,672...152,129,619
Ensembl chr 6:151,656,691...152,129,619 		JBrowse link
G ESR2 estrogen receptor 2 increases expression ISO notoginsenoside R1 results in increased expression of ESR2 CTD PMID:24720662 NCBI chr14:64,226,707...64,338,613
Ensembl chr14:64,084,232...64,338,112 		JBrowse link
G F3 coagulation factor III, tissue factor multiple interactions EXP notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased expression of F3 mRNA]; notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased expression of F3 protein] CTD PMID:9102164 NCBI chr 1:94,529,173...94,541,759
Ensembl chr 1:94,529,173...94,541,759 		JBrowse link
G FAS Fas cell surface death receptor multiple interactions ISO notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased expression of FAS mRNA] CTD PMID:23170834 NCBI chr10:88,964,050...89,017,059
Ensembl chr10:88,953,813...89,029,605 		JBrowse link
G FN1 fibronectin 1 multiple interactions EXP notoginsenoside R1 inhibits the reaction [Hydrogen Peroxide results in increased expression of and results in increased secretion of FN1 protein]; notoginsenoside R1 inhibits the reaction [Hydrogen Peroxide results in increased expression of FN1 mRNA]; notoginsenoside R1 inhibits the reaction [TNF protein results in increased expression of and results in increased secretion of FN1 protein]; notoginsenoside R1 inhibits the reaction [TNF protein results in increased expression of FN1 mRNA] CTD PMID:16632126 NCBI chr 2:215,360,865...215,436,068
Ensembl chr 2:215,360,440...215,436,073 		JBrowse link
G GCLC glutamate-cysteine ligase catalytic subunit multiple interactions
increases expression		 ISO Cycloheximide inhibits the reaction [notoginsenoside R1 results in increased expression of GCLC protein]; Dactinomycin inhibits the reaction [notoginsenoside R1 results in increased expression of GCLC protein]; fulvestrant inhibits the reaction [notoginsenoside R1 results in increased expression of GCLC protein]; NFE2L2 promotes the reaction [notoginsenoside R1 results in increased expression of GCLC protein]; notoginsenoside R1 promotes the reaction [Hydrogen Peroxide results in increased expression of GCLC protein] CTD PMID:24437944 NCBI chr 6:53,497,341...53,545,101
Ensembl chr 6:53,497,341...53,616,970 		JBrowse link
G GRIN1 glutamate ionotropic receptor NMDA type subunit 1 multiple interactions EXP [GRIN1 protein co-treated with GRIN2B protein] results in increased susceptibility to notoginsenoside R1 CTD PMID:19224577 NCBI chr 9:137,139,154...137,168,756
Ensembl chr 9:137,138,346...137,168,756 		JBrowse link
G GRIN2B glutamate ionotropic receptor NMDA type subunit 2B multiple interactions EXP [GRIN1 protein co-treated with GRIN2B protein] results in increased susceptibility to notoginsenoside R1 CTD PMID:19224577 NCBI chr12:13,537,337...13,982,134
Ensembl chr12:13,437,942...13,982,002 		JBrowse link
G GSK3B glycogen synthase kinase 3 beta multiple interactions
increases expression		 ISO fulvestrant inhibits the reaction [notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in decreased expression of GSK3B protein modified form]]; notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in decreased expression of GSK3B protein modified form]; wortmannin inhibits the reaction [notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in decreased expression of GSK3B protein modified form]]
notoginsenoside R1 results in increased expression of GSK3B protein modified form		 CTD PMID:23170834 PMID:24720662 NCBI chr 3:119,821,321...120,094,447
Ensembl chr 3:119,821,321...120,094,994 		JBrowse link
G HMOX1 heme oxygenase 1 multiple interactions
increases expression		 ISO [astragaloside A co-treated with ginsenoside Rg1 co-treated with ginsenoside Rb1 co-treated with notoginsenoside R1] results in increased expression of HMOX1 mRNA; [astragaloside A co-treated with ginsenoside Rg1 co-treated with ginsenoside Rb1 co-treated with notoginsenoside R1] results in increased expression of HMOX1 protein
notoginsenoside R1 results in increased expression of HMOX1; notoginsenoside R1 results in increased expression of HMOX1 protein
Cycloheximide inhibits the reaction [notoginsenoside R1 results in increased expression of HMOX1 protein]; Dactinomycin inhibits the reaction [notoginsenoside R1 results in increased expression of HMOX1 protein]; fulvestrant inhibits the reaction [notoginsenoside R1 results in increased expression of HMOX1 protein]; NFE2L2 promotes the reaction [notoginsenoside R1 results in increased expression of HMOX1 protein]; notoginsenoside R1 promotes the reaction [Hydrogen Peroxide results in increased expression of HMOX1 protein]		 CTD PMID:24437944 PMID:24720662 PMID:25422538 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214 		JBrowse link
G ICAM1 intercellular adhesion molecule 1 multiple interactions ISO notoginsenoside R1 inhibits the reaction [Dextran Sulfate results in increased expression of ICAM1 mRNA]; notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased expression of ICAM1 mRNA]; notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased expression of ICAM1 protein] CTD PMID:23170834 PMID:25472953 NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615 		JBrowse link
G IDE insulin degrading enzyme multiple interactions
increases expression		 ISO 2-chloro-5-nitrobenzanilide inhibits the reaction [notoginsenoside R1 results in increased expression of IDE] CTD PMID:25714973 NCBI chr10:92,451,684...92,574,093
Ensembl chr10:92,451,684...92,574,096 		JBrowse link
G IFNG interferon gamma multiple interactions ISO notoginsenoside R1 inhibits the reaction [APOE gene mutant form results in increased expression of IFNG protein]; notoginsenoside R1 inhibits the reaction [Dextran Sulfate results in increased expression of IFNG mRNA]; notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased expression of IFNG mRNA]; notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased expression of IFNG protein] CTD PMID:23170834 PMID:24933211 PMID:25472953 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740 		JBrowse link
G IKBKB inhibitor of nuclear factor kappa B kinase subunit beta multiple interactions ISO notoginsenoside R1 inhibits the reaction [Dextran Sulfate results in increased expression of IKBKB protein modified form] CTD PMID:25472953 NCBI chr 8:42,271,302...42,332,460
Ensembl chr 8:42,271,302...42,332,460 		JBrowse link
G IL10 interleukin 10 multiple interactions ISO notoginsenoside R1 promotes the reaction [Lipopolysaccharides results in increased expression of IL10 protein] CTD PMID:23170834 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541 		JBrowse link
G IL15 interleukin 15 multiple interactions ISO notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased expression of IL15 mRNA] CTD PMID:25472953 NCBI chr 4:141,636,583...141,733,987
Ensembl chr 4:141,636,583...141,733,987 		JBrowse link
G IL1A interleukin 1 alpha multiple interactions ISO notoginsenoside R1 inhibits the reaction [Dextran Sulfate results in increased expression of IL1A mRNA] CTD PMID:25472953 NCBI chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493 		JBrowse link
G IL1B interleukin 1 beta multiple interactions ISO notoginsenoside R1 inhibits the reaction [Dextran Sulfate results in increased expression of IL1B mRNA]; notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B protein]
1,3-bis(4-hydroxyphenyl)-4-methyl-5-(4-(2-piperidinylethoxy)phenol)-1H-pyrazole inhibits the reaction [notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]]; fulvestrant inhibits the reaction [notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]]; notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]		 CTD PMID:23170834 PMID:25472953 PMID:25738436 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL2 interleukin 2 multiple interactions ISO notoginsenoside R1 inhibits the reaction [APOE gene mutant form results in increased expression of IL2 protein]; notoginsenoside R1 inhibits the reaction [Dextran Sulfate results in increased expression of IL2 mRNA] CTD PMID:24933211 PMID:25472953 NCBI chr 4:122,451,470...122,456,725
Ensembl chr 4:122,451,470...122,456,725 		JBrowse link
G IL6 interleukin 6 multiple interactions ISO notoginsenoside R1 inhibits the reaction [APOE gene mutant form results in increased expression of IL6 protein]; notoginsenoside R1 inhibits the reaction [Dextran Sulfate results in increased expression of IL6 mRNA]; notoginsenoside R1 inhibits the reaction [Dextran Sulfate results in increased expression of IL6 protein]; notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]; notoginsenoside R1 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein]
1,3-bis(4-hydroxyphenyl)-4-methyl-5-(4-(2-piperidinylethoxy)phenol)-1H-pyrazole inhibits the reaction [notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]]; fulvestrant inhibits the reaction [notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]]; notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]		 CTD PMID:17655881 PMID:23170834 PMID:24933211 PMID:25472953 PMID:25738436 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G ILK integrin linked kinase multiple interactions ISO notoginsenoside R1 inhibits the reaction [Streptozocin results in increased activity of ILK protein] CTD PMID:25503068 NCBI chr11:6,603,774...6,610,870
Ensembl chr11:6,603,708...6,610,874 		JBrowse link
G ITGA3 integrin subunit alpha 3 multiple interactions ISO notoginsenoside R1 inhibits the reaction [Glucose results in decreased expression of ITGA3 mRNA]; notoginsenoside R1 inhibits the reaction [Glucose results in decreased expression of ITGA3 protein]; notoginsenoside R1 inhibits the reaction [Streptozocin results in decreased expression of ITGA3 mRNA]; notoginsenoside R1 inhibits the reaction [Streptozocin results in decreased expression of ITGA3 protein] CTD PMID:25503068 NCBI chr17:50,056,110...50,090,481
Ensembl chr17:50,055,968...50,090,481 		JBrowse link
G ITGAM integrin subunit alpha M multiple interactions ISO notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased expression of ITGAM protein] CTD PMID:17655881 NCBI chr16:31,259,975...31,332,877
Ensembl chr16:31,259,967...31,332,892 		JBrowse link
G ITGB1 integrin subunit beta 1 multiple interactions ISO notoginsenoside R1 inhibits the reaction [Glucose results in decreased expression of ITGB1 mRNA]; notoginsenoside R1 inhibits the reaction [Glucose results in decreased expression of ITGB1 protein]; notoginsenoside R1 inhibits the reaction [Streptozocin results in decreased expression of ITGB1 mRNA]; notoginsenoside R1 inhibits the reaction [Streptozocin results in decreased expression of ITGB1 protein] CTD PMID:25503068 NCBI chr10:32,900,318...32,958,230
Ensembl chr10:32,887,273...33,005,792 		JBrowse link
G ITGB2 integrin subunit beta 2 decreases expression
multiple interactions		 ISO notoginsenoside R1 results in decreased expression of ITGB2 protein
notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased expression of ITGB2 protein]		 CTD PMID:17655881 PMID:18176958 NCBI chr21:44,885,953...44,928,815
Ensembl chr21:44,885,953...44,931,989 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 multiple interactions
increases phosphorylation		 ISO
EXP		 fulvestrant inhibits the reaction [notoginsenoside R1 results in increased phosphorylation of MAPK1 protein]; notoginsenoside R1 inhibits the reaction [[Oxygen deficiency co-treated with Carbon Dioxide] results in increased expression of MAPK1 mRNA]; notoginsenoside R1 inhibits the reaction [[Oxygen deficiency co-treated with Carbon Dioxide] results in increased phosphorylation of MAPK1 protein]; notoginsenoside R1 inhibits the reaction [APP protein modified form results in increased phosphorylation of MAPK1 protein]
notoginsenoside R1 inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK1 protein]; notoginsenoside R1 inhibits the reaction [TNF protein results in increased phosphorylation of MAPK1 protein]		 CTD PMID:16458614 PMID:16632126 PMID:24437944 PMID:24975829 PMID:25004876 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 multiple interactions
increases phosphorylation		 ISO
EXP		 fulvestrant inhibits the reaction [notoginsenoside R1 results in increased phosphorylation of MAPK3 protein]; notoginsenoside R1 inhibits the reaction [[Oxygen deficiency co-treated with Carbon Dioxide] results in increased expression of MAPK3 mRNA]; notoginsenoside R1 inhibits the reaction [[Oxygen deficiency co-treated with Carbon Dioxide] results in increased phosphorylation of MAPK3 protein]; notoginsenoside R1 inhibits the reaction [APP protein modified form results in increased phosphorylation of MAPK3 protein]
notoginsenoside R1 inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK3 protein]; notoginsenoside R1 inhibits the reaction [TNF protein results in increased phosphorylation of MAPK3 protein]		 CTD PMID:16458614 PMID:16632126 PMID:24437944 PMID:24975829 PMID:25004876 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506 		JBrowse link
G MAPK8 mitogen-activated protein kinase 8 multiple interactions ISO notoginsenoside R1 inhibits the reaction [APP protein modified form results in increased phosphorylation of MAPK8 protein] CTD PMID:24975829 NCBI chr10:48,306,677...48,439,360
Ensembl chr10:48,306,639...48,439,360 		JBrowse link
G MAPK9 mitogen-activated protein kinase 9 multiple interactions ISO notoginsenoside R1 inhibits the reaction [APP protein modified form results in increased phosphorylation of MAPK9 protein] CTD PMID:24975829 NCBI chr 5:180,233,143...180,292,083
Ensembl chr 5:180,233,143...180,292,099 		JBrowse link
G MIR126 microRNA 126 multiple interactions ISO notoginsenoside R1 inhibits the reaction [APOE gene mutant form results in increased expression of MIR126A mRNA] CTD PMID:24933211 NCBI chr 9:136,670,602...136,670,686
Ensembl chr 9:136,670,602...136,670,686 		JBrowse link
G MIR20A microRNA 20a multiple interactions ISO notoginsenoside R1 inhibits the reaction [APOE gene mutant form results in decreased expression of MIR20A mRNA] CTD PMID:24933211 NCBI chr13:91,351,065...91,351,135
Ensembl chr13:91,351,065...91,351,135 		JBrowse link
G MIR21 microRNA 21 multiple interactions ISO notoginsenoside R1 inhibits the reaction [APOE gene mutant form results in increased expression of MIR21A mRNA] CTD PMID:24933211 NCBI chr17:59,841,266...59,841,337
Ensembl chr17:59,841,266...59,841,337 		JBrowse link
G MPO myeloperoxidase multiple interactions
decreases expression		 ISO notoginsenoside R1 inhibits the reaction [Dextran Sulfate results in increased activity of MPO protein]; notoginsenoside R1 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]
notoginsenoside R1 results in decreased expression of MPO protein		 CTD PMID:20023602 PMID:25472953 NCBI chr17:58,269,855...58,280,935
Ensembl chr17:58,269,855...58,280,935 		JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 affects localization
multiple interactions		 ISO notoginsenoside R1 affects the localization of NFE2L2 protein
NFE2L2 promotes the reaction [notoginsenoside R1 results in increased expression of GCLC protein]; NFE2L2 promotes the reaction [notoginsenoside R1 results in increased expression of HMOX1 protein]; NFE2L2 promotes the reaction [notoginsenoside R1 results in increased expression of NQO1 protein]; notoginsenoside R1 promotes the reaction [Hydrogen Peroxide affects the localization of NFE2L2 protein]
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [notoginsenoside R1 inhibits the reaction [triethylene glycol dimethacrylate results in decreased expression of and affects the localization of NFE2L2 protein]]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [notoginsenoside R1 results in increased expression of and affects the localization of NFE2L2 protein]; [astragaloside A co-treated with ginsenoside Rg1 co-treated with ginsenoside Rb1 co-treated with notoginsenoside R1] affects the localization of NFE2L2 protein; notoginsenoside R1 inhibits the reaction [triethylene glycol dimethacrylate results in decreased expression of and affects the localization of NFE2L2 protein]; notoginsenoside R1 results in increased expression of and affects the localization of NFE2L2 protein		 CTD PMID:24437944 PMID:24720662 PMID:25422538 PMID:33689844 NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756 		JBrowse link
G NFKBIA NFKB inhibitor alpha multiple interactions EXP
ISO		 notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased degradation of NFKBIA protein]; notoginsenoside R1 promotes the reaction [Lipopolysaccharides results in increased expression of NFKBIA mRNA]
fulvestrant inhibits the reaction [notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in decreased expression of NFKBIA protein]]; notoginsenoside R1 inhibits the reaction [Dextran Sulfate results in increased phosphorylation of NFKBIA protein]; notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in decreased expression of NFKBIA protein]; wortmannin inhibits the reaction [notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in decreased expression of NFKBIA protein]]		 CTD PMID:9102164 PMID:23170834 PMID:25472953 PMID:25738436 NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749 		JBrowse link
G NOS2 nitric oxide synthase 2 multiple interactions ISO notoginsenoside R1 inhibits the reaction [Dextran Sulfate results in increased expression of NOS2 mRNA]; notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]
[notoginsenoside R1 results in increased phosphorylation of and results in increased activity of NOS2 protein] which results in increased chemical synthesis of Nitric Oxide; notoginsenoside R1 results in increased phosphorylation of and results in increased activity of NOS2 protein		 CTD PMID:23170834 PMID:25472953 PMID:26045775 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529 		JBrowse link
G NOS3 nitric oxide synthase 3 multiple interactions ISO notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in decreased expression of NOS3 protein] CTD PMID:23170834 NCBI chr 7:150,991,017...151,014,588
Ensembl chr 7:150,991,017...151,014,588 		JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 multiple interactions
increases expression		 ISO Cycloheximide inhibits the reaction [notoginsenoside R1 results in increased expression of NQO1 protein]; Dactinomycin inhibits the reaction [notoginsenoside R1 results in increased expression of NQO1 protein]; fulvestrant inhibits the reaction [notoginsenoside R1 results in increased expression of NQO1 protein]; NFE2L2 promotes the reaction [notoginsenoside R1 results in increased expression of NQO1 protein]; notoginsenoside R1 promotes the reaction [Hydrogen Peroxide results in increased expression of NQO1 protein] CTD PMID:24437944 NCBI chr16:69,709,401...69,726,560
Ensembl chr16:69,706,996...69,726,668 		JBrowse link
G NR1I2 nuclear receptor subfamily 1 group I member 2 multiple interactions
increases activity
increases response to substance		 EXP
ISO		 notoginsenoside R1 binds to and results in increased activity of NR1I2 protein; NR1I2 protein promotes the reaction [notoginsenoside R1 results in increased expression of ABCB1 mRNA]; NR1I2 protein promotes the reaction [notoginsenoside R1 results in increased expression of UGT1A1 mRNA]
notoginsenoside R1 results in increased activity of NR1I2 protein
NR1I2 protein results in increased susceptibility to notoginsenoside R1		 CTD PMID:25472953 NCBI chr 3:119,782,101...119,818,487
Ensembl chr 3:119,780,484...119,818,487 		JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 multiple interactions ISO notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased expression of PARP1 protein modified form] CTD PMID:23170834 NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154 		JBrowse link
G PLAT plasminogen activator, tissue type increases expression
multiple interactions		 EXP notoginsenoside R1 results in increased expression of PLAT mRNA; notoginsenoside R1 results in increased expression of PLAT protein
notoginsenoside R1 results in increased expression of [PLAT protein binds to SERPINE1 protein]		 CTD PMID:8018658 PMID:9220151 NCBI chr 8:42,174,718...42,207,565
Ensembl chr 8:42,174,718...42,207,709 		JBrowse link
G PLAU plasminogen activator, urokinase increases expression EXP notoginsenoside R1 results in increased expression of PLAU mRNA; notoginsenoside R1 results in increased expression of PLAU protein CTD PMID:9220151 NCBI chr10:73,909,164...73,917,494
Ensembl chr10:73,909,177...73,917,496 		JBrowse link
G PPARG peroxisome proliferator activated receptor gamma multiple interactions
increases expression		 ISO 2-chloro-5-nitrobenzanilide inhibits the reaction [notoginsenoside R1 results in increased expression of PPARG] CTD PMID:25714973 NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356 		JBrowse link
G PPP1R12A protein phosphatase 1 regulatory subunit 12A multiple interactions ISO 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid inhibits the reaction [notoginsenoside R1 inhibits the reaction [[Oxygen co-treated with [Oxygen deficiency co-treated with Glucose deficiency]] results in increased phosphorylation of PPP1R12A protein]]; notoginsenoside R1 inhibits the reaction [[Oxygen co-treated with [Oxygen deficiency co-treated with Glucose deficiency]] results in increased phosphorylation of PPP1R12A protein] CTD PMID:25305180 NCBI chr12:79,773,563...79,935,460
Ensembl chr12:79,773,563...79,935,460 		JBrowse link
G PSEN1 presenilin 1 multiple interactions ISO notoginsenoside R1 inhibits the reaction [[APP gene mutant form co-treated with PSEN1 gene mutant form] results in increased expression of APP protein modified form] CTD PMID:25714973 NCBI chr14:73,136,417...73,223,691
Ensembl chr14:73,136,418...73,223,691 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO notoginsenoside R1 inhibits the reaction [Dextran Sulfate results in increased expression of PTGS2 mRNA]; notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA] CTD PMID:25472953 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit multiple interactions ISO notoginsenoside R1 inhibits the reaction [Dextran Sulfate results in increased expression of RELA protein modified form]; notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased expression of RELA protein modified form]
1,3-bis(4-hydroxyphenyl)-4-methyl-5-(4-(2-piperidinylethoxy)phenol)-1H-pyrazole inhibits the reaction [notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of and affects the localization of RELA protein]]; notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of and affects the localization of RELA protein]		 CTD PMID:23170834 PMID:25472953 PMID:25738436 NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090 		JBrowse link
G ROCK1 Rho associated coiled-coil containing protein kinase 1 multiple interactions ISO notoginsenoside R1 inhibits the reaction [[Oxygen co-treated with [Oxygen deficiency co-treated with Glucose deficiency]] results in increased expression of ROCK1 protein] CTD PMID:25305180 NCBI chr18:20,946,906...21,111,813
Ensembl chr18:20,944,612...21,111,813 		JBrowse link
G RUNX2 RUNX family transcription factor 2 increases expression
multiple interactions		 EXP notoginsenoside R1 results in increased expression of RUNX2 mRNA
fulvestrant inhibits the reaction [notoginsenoside R1 results in increased expression of RUNX2 mRNA]		 CTD PMID:26362186 NCBI chr 6:45,328,330...45,551,082
Ensembl chr 6:45,328,157...45,664,349 		JBrowse link
G SELE selectin E decreases expression ISO notoginsenoside R1 results in decreased expression of SELE protein CTD PMID:18176958 NCBI chr 1:169,722,640...169,734,079
Ensembl chr 1:169,722,640...169,764,705 		JBrowse link
G SERPINE1 serpin family E member 1 multiple interactions
decreases activity		 EXP
ISO		 notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased expression of SERPINE1 mRNA]; notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased expression of SERPINE1 protein]; notoginsenoside R1 inhibits the reaction [TNF protein results in increased expression of and results in increased secretion of SERPINE1 protein]; notoginsenoside R1 inhibits the reaction [TNF protein results in increased expression of SERPINE1 mRNA]; notoginsenoside R1 results in increased expression of [PLAT protein binds to SERPINE1 protein]
notoginsenoside R1 results in decreased activity of SERPINE1 protein		 CTD PMID:8018658 PMID:9102164 PMID:16458614 NCBI chr 7:101,127,104...101,139,247
Ensembl chr 7:101,127,104...101,139,247 		JBrowse link
G SLCO1B3 solute carrier organic anion transporter family member 1B3 multiple interactions EXP
ISO		 SLCO1B3 protein binds to and results in increased transport of notoginsenoside R1
SLCO1B2 protein binds to and results in increased transport of notoginsenoside R1		 CTD PMID:25297453 NCBI chr12:20,810,705...20,916,911
Ensembl chr12:20,810,702...20,916,911 		JBrowse link
G SP7 Sp7 transcription factor multiple interactions
increases expression		 EXP fulvestrant inhibits the reaction [notoginsenoside R1 results in increased expression of SP7 mRNA] CTD PMID:26362186 NCBI chr12:53,326,575...53,344,793
Ensembl chr12:53,326,575...53,345,315 		JBrowse link
G SPARC secreted protein acidic and cysteine rich multiple interactions
increases expression		 EXP fulvestrant inhibits the reaction [notoginsenoside R1 results in increased expression of SPARC mRNA] CTD PMID:26362186 NCBI chr 5:151,661,096...151,686,915
Ensembl chr 5:151,661,096...151,686,975 		JBrowse link
G SQSTM1 sequestosome 1 multiple interactions
affects localization		 ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [notoginsenoside R1 affects the localization of SQSTM1 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [notoginsenoside R1 inhibits the reaction [triethylene glycol dimethacrylate affects the localization of SQSTM1 protein]]; notoginsenoside R1 inhibits the reaction [triethylene glycol dimethacrylate affects the localization of SQSTM1 protein] CTD PMID:33689844 NCBI chr 5:179,806,393...179,838,078
Ensembl chr 5:179,806,398...179,838,078 		JBrowse link
G TNF tumor necrosis factor multiple interactions
decreases expression		 EXP
ISO		 notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; notoginsenoside R1 inhibits the reaction [TNF protein results in increased expression of and results in increased secretion of FN1 protein]; notoginsenoside R1 inhibits the reaction [TNF protein results in increased expression of and results in increased secretion of SERPINE1 protein]; notoginsenoside R1 inhibits the reaction [TNF protein results in increased expression of FN1 mRNA]; notoginsenoside R1 inhibits the reaction [TNF protein results in increased expression of SERPINE1 mRNA]; notoginsenoside R1 inhibits the reaction [TNF protein results in increased phosphorylation of MAPK1 protein]; notoginsenoside R1 inhibits the reaction [TNF protein results in increased phosphorylation of MAPK3 protein]
notoginsenoside R1 results in decreased expression of TNF
1,3-bis(4-hydroxyphenyl)-4-methyl-5-(4-(2-piperidinylethoxy)phenol)-1H-pyrazole inhibits the reaction [notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]]; fulvestrant inhibits the reaction [notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]]; notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]
notoginsenoside R1 inhibits the reaction [APOE gene mutant form results in increased expression of TNF protein]; notoginsenoside R1 inhibits the reaction [Dextran Sulfate results in increased expression of TNF mRNA]; notoginsenoside R1 inhibits the reaction [Dextran Sulfate results in increased expression of TNF protein]; notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; notoginsenoside R1 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]		 CTD PMID:9102164 PMID:16458614 PMID:16632126 PMID:20023602 PMID:23170834 More... NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TNFRSF1A TNF receptor superfamily member 1A multiple interactions ISO notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased expression of TNFRSF1A mRNA] CTD PMID:23170834 NCBI chr12:6,328,771...6,342,076
Ensembl chr12:6,328,757...6,342,114 		JBrowse link
G TP53 tumor protein p53 multiple interactions ISO notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased expression of TRP53 mRNA]; notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased expression of TRP53 protein] CTD PMID:23170834 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,546 		JBrowse link
G UGT1A1 UDP glucuronosyltransferase family 1 member A1 increases expression
multiple interactions		 EXP
ISO		 notoginsenoside R1 results in increased expression of UGT1A1 mRNA
NR1I2 protein promotes the reaction [notoginsenoside R1 results in increased expression of UGT1A1 mRNA]		 CTD PMID:25472953 NCBI chr 2:233,760,270...233,773,300
Ensembl chr 2:233,760,270...233,773,300 		JBrowse link
G VCAM1 vascular cell adhesion molecule 1 multiple interactions ISO notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased expression of VCAM1 protein] CTD PMID:23170834 NCBI chr 1:100,719,742...100,739,045
Ensembl chr 1:100,719,742...100,739,045 		JBrowse link
oleuropein term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACE angiotensin I converting enzyme multiple interactions ISO oleuropein inhibits the reaction [Isoproterenol results in increased activity of ACE protein] CTD PMID:26056852 NCBI chr17:63,477,061...63,498,373
Ensembl chr17:63,477,061...63,498,380 		JBrowse link
G ACTA2 actin alpha 2, smooth muscle multiple interactions ISO oleuropein inhibits the reaction [Rotenone results in increased expression of ACTA2 protein] CTD PMID:36774383 NCBI chr10:88,935,074...88,991,337
Ensembl chr10:88,934,822...88,991,339 		JBrowse link
G ADIPOQ adiponectin, C1Q and collagen domain containing multiple interactions ISO oleuropein inhibits the reaction [Cholesterol, Dietary results in decreased secretion of ADIPOQ protein] CTD PMID:27019295 NCBI chr 3:186,842,710...186,858,463
Ensembl chr 3:186,842,704...186,858,463 		JBrowse link
G AKT1 AKT serine/threonine kinase 1 multiple interactions ISO oleuropein inhibits the reaction [Rotenone results in decreased phosphorylation of AKT1 protein]; oleuropein inhibits the reaction [TNF protein results in increased phosphorylation of AKT1 protein] CTD PMID:34126350 PMID:36774383 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,759 		JBrowse link
G BAX BCL2 associated X, apoptosis regulator multiple interactions ISO oleuropein inhibits the reaction [Acrolein results in increased expression of BAX mRNA]; oleuropein inhibits the reaction [Acrolein results in increased expression of BAX protein]
oleuropein inhibits the reaction [Rotenone results in increased expression of BAX protein]		 CTD PMID:29414845 PMID:36774383 NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798 		JBrowse link
G BCL2 BCL2 apoptosis regulator multiple interactions ISO oleuropein inhibits the reaction [Acrolein results in decreased expression of BCL2 mRNA]; oleuropein inhibits the reaction [Acrolein results in decreased expression of BCL2 protein]; oleuropein inhibits the reaction [decamethrin results in decreased expression of BCL2 protein]
oleuropein affects the reaction [Rotenone results in decreased expression of BCL2 protein]		 CTD PMID:28595958 PMID:29414845 PMID:36774383 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128 		JBrowse link
G BDNF brain derived neurotrophic factor multiple interactions ISO oleuropein affects the reaction [Rotenone results in decreased expression of BDNF protein] CTD PMID:36774383 NCBI chr11:27,654,893...27,722,030
Ensembl chr11:27,654,893...27,722,058 		JBrowse link
G CASP3 caspase 3 multiple interactions ISO oleuropein inhibits the reaction [Rotenone results in increased cleavage of CASP3 protein] CTD PMID:36774383 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062 		JBrowse link
G CAT catalase increases activity
multiple interactions		 ISO oleuropein results in increased activity of CAT protein
oleuropein inhibits the reaction [Rotenone results in decreased activity of CAT protein]
oleuropein inhibits the reaction [decamethrin results in decreased activity of CAT protein]		 CTD PMID:18823963 PMID:28595958 PMID:36774383 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060 		JBrowse link
G CREB1 cAMP responsive element binding protein 1 multiple interactions ISO oleuropein inhibits the reaction [Rotenone results in decreased phosphorylation of CREB1 protein] CTD PMID:36774383 NCBI chr 2:207,529,962...207,605,988
Ensembl chr 2:207,529,737...207,605,988 		JBrowse link
G CSF1R colony stimulating factor 1 receptor multiple interactions ISO oleuropein inhibits the reaction [TNF protein results in increased export of CSF1R protein] CTD PMID:34126350 NCBI chr 5:150,053,295...150,113,365
Ensembl chr 5:150,053,291...150,113,372 		JBrowse link
G CYP19A1 cytochrome P450 family 19 subfamily A member 1 decreases activity EXP oleuropein results in decreased activity of CYP19A1 protein CTD PMID:17910019 NCBI chr15:51,208,057...51,338,596
Ensembl chr15:51,208,057...51,338,601 		JBrowse link
G DDIT3 DNA damage inducible transcript 3 multiple interactions ISO oleuropein inhibits the reaction [Acrolein results in increased expression of DDIT3 protein] CTD PMID:29414845 NCBI chr12:57,516,588...57,520,517
Ensembl chr12:57,516,588...57,521,737 		JBrowse link
G FASN fatty acid synthase multiple interactions ISO oleuropein inhibits the reaction [Cholesterol, Dietary results in increased expression of FASN protein] CTD PMID:27019295 NCBI chr17:82,078,338...82,098,236
Ensembl chr17:82,078,338...82,098,294 		JBrowse link
G GPT glutamic--pyruvic transaminase multiple interactions ISO oleuropein inhibits the reaction [Cholesterol, Dietary results in increased activity of GPT protein]; oleuropein inhibits the reaction [decamethrin results in increased expression of GPT protein]; oleuropein inhibits the reaction [Isoproterenol results in increased expression of and results in increased secretion of GPT protein] CTD PMID:26056852 PMID:27019295 PMID:28595958 NCBI chr 8:144,503,068...144,507,172
Ensembl chr 8:144,502,973...144,507,174 		JBrowse link
G GSK3B glycogen synthase kinase 3 beta multiple interactions ISO oleuropein inhibits the reaction [Rotenone results in decreased expression of and results in decreased phosphorylation of GSK3B protein] CTD PMID:36774383 NCBI chr 3:119,821,321...120,094,447
Ensembl chr 3:119,821,321...120,094,994 		JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 multiple interactions ISO oleuropein inhibits the reaction [Acrolein results in increased expression of HSPA5 protein] CTD PMID:29414845 NCBI chr 9:125,234,853...125,241,343
Ensembl chr 9:125,234,853...125,241,382 		JBrowse link
G ICAM1 intercellular adhesion molecule 1 multiple interactions EXP oleuropein inhibits the reaction [Lipopolysaccharides results in increased expression of ICAM1 protein] CTD PMID:12615669 NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615 		JBrowse link
G IL6 interleukin 6 multiple interactions ISO oleuropein inhibits the reaction [TNF protein results in increased export of IL6 protein] CTD PMID:34126350 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G LDHA lactate dehydrogenase A multiple interactions ISO oleuropein inhibits the reaction [Isoproterenol results in increased expression of and results in increased secretion of LDHA protein] CTD PMID:26056852 NCBI chr11:18,394,563...18,408,425
Ensembl chr11:18,394,560...18,408,425 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 multiple interactions ISO oleuropein inhibits the reaction [TNF protein results in increased phosphorylation of MAPK1 protein] CTD PMID:34126350 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 multiple interactions ISO oleuropein inhibits the reaction [TNF protein results in increased phosphorylation of MAPK3 protein] CTD PMID:34126350 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506 		JBrowse link
G MMP9 matrix metallopeptidase 9 multiple interactions EXP oleuropein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; oleuropein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein] CTD PMID:22595400 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561 		JBrowse link
G NOS2 nitric oxide synthase 2 multiple interactions ISO oleuropein inhibits the reaction [Doxorubicin results in increased expression of NOS2 protein] CTD PMID:17223128 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529 		JBrowse link
G NTRK2 neurotrophic receptor tyrosine kinase 2 multiple interactions ISO oleuropein inhibits the reaction [Rotenone results in decreased expression of and results in decreased phosphorylation of NTRK2 protein] CTD PMID:36774383 NCBI chr 9:84,668,522...85,027,054
Ensembl chr 9:84,668,375...85,095,751 		JBrowse link
G PNLIP pancreatic lipase multiple interactions ISO oleuropein inhibits the reaction [Isoproterenol results in increased activity of PNLIP protein] CTD PMID:26056852 NCBI chr10:116,545,931...116,567,855
Ensembl chr10:116,545,931...116,567,855 		JBrowse link
G PPARG peroxisome proliferator activated receptor gamma multiple interactions ISO oleuropein inhibits the reaction [Cholesterol, Dietary results in increased expression of PPARG protein] CTD PMID:27019295 NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP
ISO		 oleuropein inhibits the reaction [[Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein] which results in increased chemical synthesis of Dinoprostone]; oleuropein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]
oleuropein inhibits the reaction [decamethrin results in increased expression of PTGS2 protein]		 CTD PMID:22595400 PMID:28595958 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit multiple interactions EXP oleuropein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased localization of and results in increased activity of RELA protein] CTD PMID:22595400 NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090 		JBrowse link
G SELE selectin E multiple interactions EXP oleuropein inhibits the reaction [Lipopolysaccharides results in increased expression of SELE protein] CTD PMID:12615669 NCBI chr 1:169,722,640...169,734,079
Ensembl chr 1:169,722,640...169,764,705 		JBrowse link
G SREBF1 sterol regulatory element binding transcription factor 1 multiple interactions ISO oleuropein inhibits the reaction [Cholesterol, Dietary results in increased expression of SREBF1 protein] CTD PMID:27019295 NCBI chr17:17,811,334...17,836,986
Ensembl chr17:17,810,399...17,837,002 		JBrowse link
G TH tyrosine hydroxylase multiple interactions ISO oleuropein inhibits the reaction [Rotenone results in decreased expression of TH protein] CTD PMID:36774383 NCBI chr11:2,163,929...2,171,815
Ensembl chr11:2,163,929...2,171,815 		JBrowse link
G TNF tumor necrosis factor multiple interactions EXP
ISO		 oleuropein inhibits the reaction [TNF protein results in increased expression of VCAM1 protein]
oleuropein inhibits the reaction [TNF protein results in increased export of CSF1R protein]; oleuropein inhibits the reaction [TNF protein results in increased export of IL6 protein]; oleuropein inhibits the reaction [TNF protein results in increased phosphorylation of AKT1 protein]; oleuropein inhibits the reaction [TNF protein results in increased phosphorylation of MAPK1 protein]; oleuropein inhibits the reaction [TNF protein results in increased phosphorylation of MAPK3 protein]		 CTD PMID:12615669 PMID:34126350 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TNNT1 troponin T1, slow skeletal type multiple interactions ISO oleuropein inhibits the reaction [Isoproterenol results in increased expression of and results in increased secretion of TNNT1 protein] CTD PMID:26056852 NCBI chr19:55,132,698...55,149,206
Ensembl chr19:55,132,698...55,149,206 		JBrowse link
G TP53 tumor protein p53 multiple interactions ISO oleuropein inhibits the reaction [decamethrin results in increased expression of TP53 protein] CTD PMID:28595958 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,546 		JBrowse link
G VCAM1 vascular cell adhesion molecule 1 multiple interactions EXP oleuropein inhibits the reaction [Lipopolysaccharides results in increased expression of VCAM1 mRNA]; oleuropein inhibits the reaction [Lipopolysaccharides results in increased expression of VCAM1 protein]; oleuropein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of VCAM1 protein]; oleuropein inhibits the reaction [TNF protein results in increased expression of VCAM1 protein] CTD PMID:12615669 NCBI chr 1:100,719,742...100,739,045
Ensembl chr 1:100,719,742...100,739,045 		JBrowse link
pelargonidin 3-O-beta-D-glucoside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CA1 carbonic anhydrase 1 decreases activity EXP pelargonidin-3-glucoside results in decreased activity of CA1 protein CTD PMID:28445001 NCBI chr 8:85,327,608...85,378,113
Ensembl chr 8:85,327,608...85,379,014 		JBrowse link
G CA2 carbonic anhydrase 2 decreases activity EXP pelargonidin-3-glucoside results in decreased activity of CA2 protein CTD PMID:28445001 NCBI chr 8:85,464,007...85,481,493
Ensembl chr 8:85,463,968...85,481,493 		JBrowse link
pelargonidin 3-O-beta-D-glucoside chloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CA1 carbonic anhydrase 1 decreases activity EXP pelargonidin-3-glucoside results in decreased activity of CA1 protein CTD PMID:28445001 NCBI chr 8:85,327,608...85,378,113
Ensembl chr 8:85,327,608...85,379,014 		JBrowse link
G CA2 carbonic anhydrase 2 decreases activity EXP pelargonidin-3-glucoside results in decreased activity of CA2 protein CTD PMID:28445001 NCBI chr 8:85,464,007...85,481,493
Ensembl chr 8:85,463,968...85,481,493 		JBrowse link
petunidin 3-O-beta-D-glucoside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AQP3 aquaporin 3 (Gill blood group) multiple interactions EXP [malvidin-3-glucoside co-treated with petunidin-3-glucoside] results in increased expression of AQP3 mRNA CTD PMID:33294640 NCBI chr 9:33,441,160...33,447,593
Ensembl chr 9:33,441,156...33,447,596 		JBrowse link
phlorizin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABAT 4-aminobutyrate aminotransferase decreases expression ISO Phlorhizin results in decreased expression of ABAT mRNA CTD PMID:22538082 NCBI chr16:8,674,617...8,784,570
Ensembl chr16:8,674,596...8,784,575 		JBrowse link
G ACAA1 acetyl-CoA acyltransferase 1 increases expression ISO Phlorhizin results in increased expression of ACAA1 mRNA CTD PMID:22538082 NCBI chr 3:38,122,715...38,137,127
Ensembl chr 3:38,103,129...38,137,242 		JBrowse link
G ACAA2 acetyl-CoA acyltransferase 2 decreases expression ISO Phlorhizin results in decreased expression of ACAA2 mRNA CTD PMID:22538082 NCBI chr18:49,782,164...49,813,533
Ensembl chr18:49,782,164...49,813,953 		JBrowse link
G ACAD8 acyl-CoA dehydrogenase family member 8 decreases expression ISO Phlorhizin results in decreased expression of ACAD8 mRNA CTD PMID:22538082 NCBI chr11:134,253,568...134,265,855
Ensembl chr11:134,253,548...134,265,855 		JBrowse link
G ACAD9 acyl-CoA dehydrogenase family member 9 decreases expression ISO Phlorhizin results in decreased expression of ACAD9 mRNA CTD PMID:22538082 NCBI chr 3:128,879,620...128,913,114
Ensembl chr 3:128,879,596...128,924,003 		JBrowse link
G ACADL acyl-CoA dehydrogenase long chain decreases expression ISO Phlorhizin results in decreased expression of ACADL mRNA CTD PMID:22538082 NCBI chr 2:210,187,923...210,225,447
Ensembl chr 2:210,187,126...210,225,447 		JBrowse link
G ACADM acyl-CoA dehydrogenase medium chain decreases expression ISO Phlorhizin results in decreased expression of ACADM mRNA CTD PMID:22538082 NCBI chr 1:75,724,709...75,763,679
Ensembl chr 1:75,724,431...75,787,575 		JBrowse link
G ACAT1 acetyl-CoA acetyltransferase 1 decreases expression ISO Phlorhizin results in decreased expression of ACAT1 mRNA CTD PMID:22538082 NCBI chr11:108,116,705...108,147,603
Ensembl chr11:108,116,695...108,147,603 		JBrowse link
G ACO1 aconitase 1 decreases expression ISO Phlorhizin results in decreased expression of ACO1 mRNA CTD PMID:22538082 NCBI chr 9:32,384,643...32,454,769
Ensembl chr 9:32,384,603...32,454,769 		JBrowse link
G ACOX1 acyl-CoA oxidase 1 decreases expression ISO Phlorhizin results in decreased expression of ACOX1 mRNA CTD PMID:22538082 NCBI chr17:75,941,507...75,979,166
Ensembl chr17:75,941,507...75,979,177 		JBrowse link
G ACOX2 acyl-CoA oxidase 2 decreases expression ISO Phlorhizin results in decreased expression of ACOX2 mRNA CTD PMID:22538082 NCBI chr 3:58,505,136...58,537,190
Ensembl chr 3:58,505,136...58,537,283 		JBrowse link
G ACSL1 acyl-CoA synthetase long chain family member 1 decreases expression ISO Phlorhizin results in decreased expression of ACSL1 mRNA CTD PMID:22538082 NCBI chr 4:184,755,595...184,826,594
Ensembl chr 4:184,755,595...184,826,818 		JBrowse link
G ACTB actin beta increases expression ISO Phlorhizin results in increased expression of ACTB mRNA CTD PMID:22538082 NCBI chr 7:5,527,148...5,530,601
Ensembl chr 7:5,526,409...5,563,902 		JBrowse link
G ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide decreases expression ISO Phlorhizin results in decreased expression of ADH5 mRNA CTD PMID:22538082 NCBI chr 4:99,070,978...99,088,788
Ensembl chr 4:99,070,978...99,088,801 		JBrowse link
G ADHFE1 alcohol dehydrogenase iron containing 1 decreases expression ISO Phlorhizin results in decreased expression of ADHFE1 mRNA CTD PMID:22538082 NCBI chr 8:66,432,504...66,468,907
Ensembl chr 8:66,432,492...66,468,907 		JBrowse link
G ADIPOQ adiponectin, C1Q and collagen domain containing multiple interactions ISO 2,2-bis(4-glycidyloxyphenyl)propane affects the reaction [[cobaltous chloride co-treated with Phlorhizin] affects the expression of ADIPOQ mRNA]; 2,2-bis(4-glycidyloxyphenyl)propane affects the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Phlorhizin] affects the expression of ADIPOQ mRNA]; [cobaltous chloride co-treated with Phlorhizin] affects the expression of ADIPOQ mRNA; [lipopolysaccharide, E coli O55-B5 co-treated with Phlorhizin] affects the expression of ADIPOQ mRNA CTD PMID:32408695 NCBI chr 3:186,842,710...186,858,463
Ensembl chr 3:186,842,704...186,858,463 		JBrowse link
G AKR1A1 aldo-keto reductase family 1 member A1 decreases expression ISO Phlorhizin results in decreased expression of AKR1A1 mRNA CTD PMID:22538082 NCBI chr 1:45,550,826...45,570,049
Ensembl chr 1:45,550,543...45,570,049 		JBrowse link
G AKR7A2 aldo-keto reductase family 7 member A2 increases expression ISO Phlorhizin results in increased expression of AKR7A2 mRNA CTD PMID:22538082 NCBI chr 1:19,302,708...19,312,146
Ensembl chr 1:19,303,965...19,312,144 		JBrowse link
G ALB albumin multiple interactions EXP Phlorhizin inhibits the reaction [Glucose results in decreased uptake of ALB protein] CTD PMID:16313995 NCBI chr 4:73,404,287...73,421,482
Ensembl chr 4:73,397,114...73,421,482 		JBrowse link
G ALDH2 aldehyde dehydrogenase 2 family member decreases expression
increases expression		 ISO Phlorhizin results in decreased expression of ALDH2 mRNA
Phlorhizin results in increased expression of ALDH2 mRNA		 CTD PMID:22538082 NCBI chr12:111,766,933...111,817,532
Ensembl chr12:111,766,887...111,817,532 		JBrowse link
G ALDH3A2 aldehyde dehydrogenase 3 family member A2 decreases expression ISO Phlorhizin results in decreased expression of ALDH3A2 mRNA CTD PMID:22538082 NCBI chr17:19,648,136...19,677,596
Ensembl chr17:19,648,136...19,685,760 		JBrowse link
G ALDH4A1 aldehyde dehydrogenase 4 family member A1 decreases expression ISO Phlorhizin results in decreased expression of ALDH4A1 mRNA CTD PMID:22538082 NCBI chr 1:18,871,430...18,902,555
Ensembl chr 1:18,871,430...18,902,724 		JBrowse link
G ALDH6A1 aldehyde dehydrogenase 6 family member A1 decreases expression ISO Phlorhizin results in decreased expression of ALDH6A1 mRNA CTD PMID:22538082 NCBI chr14:74,056,847...74,084,453
Ensembl chr14:74,056,847...74,084,492 		JBrowse link
G ALDH7A1 aldehyde dehydrogenase 7 family member A1 decreases expression ISO Phlorhizin results in decreased expression of ALDH7A1 mRNA CTD PMID:22538082 NCBI chr 5:126,541,841...126,595,219
Ensembl chr 5:126,531,200...126,595,362 		JBrowse link
G ANAPC2 anaphase promoting complex subunit 2 decreases expression ISO Phlorhizin results in decreased expression of ANAPC2 mRNA CTD PMID:22538082 NCBI chr 9:137,174,784...137,188,560
Ensembl chr 9:137,174,784...137,188,560 		JBrowse link
G ANAPC5 anaphase promoting complex subunit 5 decreases expression ISO Phlorhizin results in decreased expression of ANAPC5 mRNA CTD PMID:22538082 NCBI chr12:121,308,245...121,354,209
Ensembl chr12:121,308,245...121,399,896 		JBrowse link
G AOX1 aldehyde oxidase 1 decreases expression ISO Phlorhizin results in decreased expression of AOX1 mRNA CTD PMID:22538082 NCBI chr 2:200,586,014...200,682,241
Ensembl chr 2:200,586,014...200,677,064 		JBrowse link
G AOX3P aldehyde oxidase 3, pseudogene decreases expression ISO Phlorhizin results in decreased expression of AOX3 mRNA CTD PMID:22538082 NCBI chr 2:200,695,723...200,738,781
Ensembl chr 2:200,678,233...200,732,539 		JBrowse link
G APH1B aph-1 homolog B, gamma-secretase subunit increases expression ISO Phlorhizin results in increased expression of APH1B mRNA CTD PMID:22538082 NCBI chr15:63,277,605...63,309,126
Ensembl chr15:63,276,018...63,309,126 		JBrowse link
G APP amyloid beta precursor protein decreases expression ISO Phlorhizin results in decreased expression of APP mRNA CTD PMID:22538082 NCBI chr21:25,880,550...26,171,128
Ensembl chr21:25,880,535...26,171,128 		JBrowse link
G ATF3 activating transcription factor 3 decreases expression ISO Phlorhizin results in decreased expression of ATF3 mRNA CTD PMID:16123366 NCBI chr 1:212,565,407...212,620,777
Ensembl chr 1:212,565,334...212,620,777 		JBrowse link
G ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 increases expression ISO Phlorhizin results in increased expression of ATP2A2 mRNA CTD PMID:16123366 NCBI chr12:110,280,616...110,351,093
Ensembl chr12:110,280,756...110,351,093 		JBrowse link
G ATP5F1A ATP synthase F1 subunit alpha decreases expression ISO Phlorhizin results in decreased expression of ATP5F1A mRNA CTD PMID:22538082 NCBI chr18:46,080,248...46,104,227
Ensembl chr18:46,080,248...46,104,334 		JBrowse link
G ATP5F1C ATP synthase F1 subunit gamma increases expression ISO Phlorhizin results in increased expression of ATP5F1C mRNA CTD PMID:22538082 NCBI chr10:7,788,177...7,807,801
Ensembl chr10:7,788,147...7,807,815 		JBrowse link
G AUH AU RNA binding methylglutaconyl-CoA hydratase decreases expression ISO Phlorhizin results in decreased expression of AUH mRNA CTD PMID:22538082 NCBI chr 9:91,213,823...91,361,918
Ensembl chr 9:91,213,815...91,361,918 		JBrowse link
G B2M beta-2-microglobulin increases expression ISO Phlorhizin results in increased expression of B2M mRNA CTD PMID:22538082 NCBI chr15:44,711,517...44,718,145
Ensembl chr15:44,711,358...44,718,851 		JBrowse link
G BAD BCL2 associated agonist of cell death multiple interactions ISO [2,2-bis(4-glycidyloxyphenyl)propane co-treated with Phlorhizin] promotes the reaction [[cobaltous chloride co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of BAD protein] CTD PMID:32408695 NCBI chr11:64,269,828...64,284,704
Ensembl chr11:64,269,830...64,284,704 		JBrowse link
G BAG1 BAG cochaperone 1 decreases expression ISO Phlorhizin results in decreased expression of BAG1 mRNA CTD PMID:22538082 NCBI chr 9:33,252,471...33,264,708
Ensembl chr 9:33,247,820...33,264,720 		JBrowse link
G BCKDHB branched chain keto acid dehydrogenase E1 subunit beta decreases expression ISO Phlorhizin results in decreased expression of BCKDHB mRNA CTD PMID:22538082 NCBI chr 6:80,106,610...80,466,676
Ensembl chr 6:80,106,647...80,346,270 		JBrowse link
G BCL2L1 BCL2 like 1 multiple interactions ISO [2,2-bis(4-glycidyloxyphenyl)propane co-treated with Phlorhizin] promotes the reaction [[cobaltous chloride co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of BCL2L1 protein] CTD PMID:32408695 NCBI chr20:31,664,452...31,723,963
Ensembl chr20:31,664,452...31,723,989 		JBrowse link
G BIRC6 baculoviral IAP repeat containing 6 increases expression ISO Phlorhizin results in increased expression of BIRC6 mRNA CTD PMID:22538082 NCBI chr 2:32,357,023...32,618,878
Ensembl chr 2:32,357,023...32,619,571 		JBrowse link
G CAT catalase increases expression ISO Phlorhizin results in increased expression of CAT mRNA CTD PMID:22538082 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060 		JBrowse link
G CCL2 C-C motif chemokine ligand 2 multiple interactions ISO 2,2-bis(4-glycidyloxyphenyl)propane affects the reaction [[cobaltous chloride co-treated with Phlorhizin] affects the expression of CCL2 mRNA]; 2,2-bis(4-glycidyloxyphenyl)propane affects the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Phlorhizin] affects the expression of CCL2 mRNA]; [cobaltous chloride co-treated with Phlorhizin] affects the expression of CCL2 mRNA; [lipopolysaccharide, E coli O55-B5 co-treated with Phlorhizin] affects the expression of CCL2 mRNA CTD PMID:32408695 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208 		JBrowse link
G CCT7 chaperonin containing TCP1 subunit 7 decreases expression ISO Phlorhizin results in decreased expression of CCT7 mRNA CTD PMID:22538082 NCBI chr 2:73,234,308...73,253,005
Ensembl chr 2:73,233,420...73,253,021 		JBrowse link
G CHRM2 cholinergic receptor muscarinic 2 multiple interactions ISO Phlorhizin inhibits the reaction [Streptozocin results in increased expression of CHRM2 mRNA]; Phlorhizin inhibits the reaction [Streptozocin results in increased expression of CHRM2 protein] CTD PMID:18715473 NCBI chr 7:136,868,652...137,020,213
Ensembl chr 7:136,868,652...137,020,255 		JBrowse link
G CLYBL citramalyl-CoA lyase decreases expression ISO Phlorhizin results in decreased expression of CLYBL mRNA CTD PMID:22538082 NCBI chr13:99,606,690...99,909,444
Ensembl chr13:99,606,669...99,909,459 		JBrowse link
G COX15 cytochrome c oxidase assembly homolog COX15 decreases expression ISO Phlorhizin results in decreased expression of COX15 mRNA CTD PMID:22538082 NCBI chr10:99,694,293...99,732,127
Ensembl chr10:99,710,868...99,732,127 		JBrowse link
G COX17 cytochrome c oxidase copper chaperone COX17 decreases expression ISO Phlorhizin results in decreased expression of COX17 mRNA CTD PMID:22538082 NCBI chr 3:119,663,975...119,677,406
Ensembl chr 3:119,654,513...119,677,454 		JBrowse link
G COX7C cytochrome c oxidase subunit 7C increases expression ISO Phlorhizin results in increased expression of COX7C mRNA CTD PMID:22538082 NCBI chr 5:86,617,941...86,620,962
Ensembl chr 5:86,617,928...86,620,962 		JBrowse link
G COX8A cytochrome c oxidase subunit 8A decreases expression ISO Phlorhizin results in decreased expression of COX8A mRNA CTD PMID:22538082 NCBI chr11:63,974,620...63,976,543
Ensembl chr11:63,974,620...63,976,543 		JBrowse link
G CPT1A carnitine palmitoyltransferase 1A decreases expression ISO Phlorhizin results in decreased expression of CPT1A mRNA CTD PMID:16123366 PMID:22538082 NCBI chr11:68,754,620...68,844,277
Ensembl chr11:68,754,620...68,844,410 		JBrowse link
G CPT2 carnitine palmitoyltransferase 2 decreases expression ISO Phlorhizin results in decreased expression of CPT2 mRNA CTD PMID:22538082 NCBI chr 1:53,196,824...53,214,197
Ensembl chr 1:53,196,792...53,214,197 		JBrowse link
G CREBBP CREB binding protein decreases expression ISO Phlorhizin results in decreased expression of CREBBP mRNA CTD PMID:22538082 NCBI chr16:3,725,054...3,880,713
Ensembl chr16:3,725,054...3,880,713 		JBrowse link
G CS citrate synthase decreases expression ISO Phlorhizin results in decreased expression of CS mRNA CTD PMID:22538082 NCBI chr12:56,271,699...56,300,330
Ensembl chr12:56,271,699...56,300,391 		JBrowse link
G CUL1 cullin 1 decreases expression ISO Phlorhizin results in decreased expression of CUL1 mRNA CTD PMID:22538082 NCBI chr 7:148,697,756...148,801,110
Ensembl chr 7:148,697,914...148,801,110 		JBrowse link
G CYB5R3 cytochrome b5 reductase 3 decreases expression ISO Phlorhizin results in decreased expression of CYB5R3 mRNA CTD PMID:22538082 NCBI chr22:42,617,840...42,649,392
Ensembl chr22:42,615,730...42,720,870 		JBrowse link
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 decreases expression ISO Phlorhizin results in decreased expression of CYP1A2 mRNA CTD PMID:22538082 NCBI chr15:74,748,845...74,756,607
Ensembl chr15:74,748,845...74,756,607 		JBrowse link
G CYP2B6 cytochrome P450 family 2 subfamily B member 6 decreases expression ISO Phlorhizin results in decreased expression of CYP2B6 mRNA CTD PMID:22538082 NCBI chr19:40,991,282...41,018,398
Ensembl chr19:40,991,282...41,018,398 		JBrowse link
G CYP2D6 cytochrome P450 family 2 subfamily D member 6 increases expression ISO Phlorhizin results in increased expression of CYP2D6 mRNA CTD PMID:22538082 NCBI chr22:42,126,499...42,130,810
Ensembl chr22:42,126,499...42,130,865 		JBrowse link
G CYP3A5 cytochrome P450 family 3 subfamily A member 5 increases expression
decreases expression		 ISO Phlorhizin results in increased expression of CYP3A7 mRNA
Phlorhizin results in decreased expression of CYP3A7 mRNA		 CTD PMID:22538082 NCBI chr 7:99,648,194...99,679,996
Ensembl chr 7:99,648,194...99,679,996 		JBrowse link
G CYP3A7 cytochrome P450 family 3 subfamily A member 7 decreases expression
increases expression		 ISO Phlorhizin results in decreased expression of CYP3A7 mRNA
Phlorhizin results in increased expression of CYP3A7 mRNA		 CTD PMID:22538082 NCBI chr 7:99,705,036...99,735,196
Ensembl chr 7:99,705,036...99,735,196 		JBrowse link
G CYP4A22 cytochrome P450 family 4 subfamily A member 22 increases expression ISO Phlorhizin results in increased expression of CYP4A11 mRNA CTD PMID:22538082 NCBI chr 1:47,137,441...47,149,727
Ensembl chr 1:47,137,435...47,149,727 		JBrowse link
G CYP4F12 cytochrome P450 family 4 subfamily F member 12 decreases expression ISO Phlorhizin results in decreased expression of CYP4F12 mRNA CTD PMID:22538082 NCBI chr19:15,673,087...15,697,174
Ensembl chr19:15,673,018...15,697,174 		JBrowse link
G DHRS4 dehydrogenase/reductase 4 decreases expression ISO Phlorhizin results in decreased expression of DHRS4 mRNA CTD PMID:22538082 NCBI chr14:23,953,770...23,969,279
Ensembl chr14:23,953,734...23,969,279 		JBrowse link
G DLD dihydrolipoamide dehydrogenase decreases expression ISO Phlorhizin results in decreased expression of DLD mRNA CTD PMID:22538082 NCBI chr 7:107,891,107...107,921,198
Ensembl chr 7:107,891,162...107,931,730 		JBrowse link
G DNAJA2 DnaJ heat shock protein family (Hsp40) member A2 decreases expression ISO Phlorhizin results in decreased expression of DNAJA2 mRNA CTD PMID:22538082 NCBI chr16:46,955,362...46,973,674
Ensembl chr16:46,955,362...46,973,674 		JBrowse link
G DNAJA3 DnaJ heat shock protein family (Hsp40) member A3 decreases expression ISO Phlorhizin results in decreased expression of DNAJA3 mRNA CTD PMID:22538082 NCBI chr16:4,425,868...4,456,775
Ensembl chr16:4,425,805...4,456,775 		JBrowse link
G DNAJB1 DnaJ heat shock protein family (Hsp40) member B1 decreases expression
increases expression		 ISO Phlorhizin results in decreased expression of DNAJB1 mRNA
Phlorhizin results in increased expression of DNAJB1 mRNA		 CTD PMID:22538082 NCBI chr19:14,514,769...14,560,391
Ensembl chr19:14,514,769...14,560,391 		JBrowse link
G DNAJB4 DnaJ heat shock protein family (Hsp40) member B4 decreases expression ISO Phlorhizin results in decreased expression of DNAJB4 mRNA CTD PMID:22538082 NCBI chr 1:77,979,175...78,017,964
Ensembl chr 1:77,979,175...78,017,964 		JBrowse link
G DNAJB6 DnaJ heat shock protein family (Hsp40) member B6 increases expression ISO Phlorhizin results in increased expression of DNAJB6 mRNA CTD PMID:22538082 NCBI chr 7:157,337,004...157,417,439
Ensembl chr 7:157,335,381...157,417,439 		JBrowse link
G DNAJC1 DnaJ heat shock protein family (Hsp40) member C1 decreases expression ISO Phlorhizin results in decreased expression of DNAJC1 mRNA CTD PMID:22538082 NCBI chr10:21,756,548...22,003,730
Ensembl chr10:21,756,548...22,003,769 		JBrowse link
G DNAJC13 DnaJ heat shock protein family (Hsp40) member C13 decreases expression ISO Phlorhizin results in decreased expression of DNAJC13 mRNA CTD PMID:22538082 NCBI chr 3:132,417,502...132,539,032
Ensembl chr 3:132,417,502...132,539,032 		JBrowse link
G DNAJC14 DnaJ heat shock protein family (Hsp40) member C14 increases expression ISO Phlorhizin results in increased expression of DNAJC14 mRNA CTD PMID:22538082 NCBI chr12:55,820,985...55,830,775
Ensembl chr12:55,820,960...55,830,824 		JBrowse link
G DNAJC19 DnaJ heat shock protein family (Hsp40) member C19 decreases expression ISO Phlorhizin results in decreased expression of DNAJC19 mRNA CTD PMID:22538082 NCBI chr 3:180,983,709...180,989,838
Ensembl chr 3:180,983,697...180,989,774 		JBrowse link
G DNAJC3 DnaJ heat shock protein family (Hsp40) member C3 decreases expression ISO Phlorhizin results in decreased expression of DNAJC3 mRNA CTD PMID:22538082 NCBI chr13:95,677,139...95,794,988
Ensembl chr13:95,677,139...95,794,988 		JBrowse link
G DNAJC4 DnaJ heat shock protein family (Hsp40) member C4 increases expression ISO Phlorhizin results in increased expression of DNAJC4 mRNA CTD PMID:22538082 NCBI chr11:64,230,432...64,234,281
Ensembl chr11:64,230,278...64,234,286 		JBrowse link
G DNAJC5 DnaJ heat shock protein family (Hsp40) member C5 decreases expression ISO Phlorhizin results in decreased expression of DNAJC5 mRNA CTD PMID:22538082 NCBI chr20:63,895,126...63,936,011
Ensembl chr20:63,895,126...63,936,031 		JBrowse link
G ECHS1 enoyl-CoA hydratase, short chain 1 decreases expression ISO Phlorhizin results in decreased expression of ECHS1 mRNA CTD PMID:22538082 NCBI chr10:133,362,485...133,373,354
Ensembl chr10:133,362,485...133,373,354 		JBrowse link
G EP300 E1A binding protein p300 decreases expression ISO Phlorhizin results in decreased expression of EP300 mRNA CTD PMID:22538082 NCBI chr22:41,092,592...41,180,077
Ensembl chr22:41,092,510...41,180,077 		JBrowse link
G EPHX1 epoxide hydrolase 1 decreases expression ISO Phlorhizin results in decreased expression of EPHX1 mRNA CTD PMID:22538082 NCBI chr 1:225,810,124...225,845,563
Ensembl chr 1:225,810,124...225,845,563 		JBrowse link
G FAS Fas cell surface death receptor decreases expression ISO Phlorhizin results in decreased expression of FAS mRNA CTD PMID:16123366 NCBI chr10:88,964,050...89,017,059
Ensembl chr10:88,953,813...89,029,605 		JBrowse link
G FBXW7 F-box and WD repeat domain containing 7 decreases expression ISO Phlorhizin results in decreased expression of FBXW7 mRNA CTD PMID:22538082 NCBI chr 4:152,320,544...152,536,092
Ensembl chr 4:152,320,544...152,536,092 		JBrowse link
G FH fumarate hydratase decreases expression ISO Phlorhizin results in decreased expression of FH mRNA CTD PMID:22538082 NCBI chr 1:241,497,603...241,519,755
Ensembl chr 1:241,497,511...241,519,799 		JBrowse link
G FIS1 fission, mitochondrial 1 increases expression ISO Phlorhizin results in increased expression of FIS1 mRNA CTD PMID:22538082 NCBI chr 7:101,239,472...101,245,081
Ensembl chr 7:101,239,458...101,252,316 		JBrowse link
G FKBP5 FKBP prolyl isomerase 5 decreases expression ISO Phlorhizin results in decreased expression of FKBP5 mRNA CTD PMID:22538082 NCBI chr 6:35,573,590...35,728,583
Ensembl chr 6:35,573,585...35,728,583 		JBrowse link
G FMO1 flavin containing dimethylaniline monoxygenase 1 decreases expression ISO Phlorhizin results in decreased expression of FMO1 mRNA CTD PMID:22538082 NCBI chr 1:171,248,494...171,285,978
Ensembl chr 1:171,248,471...171,285,978 		JBrowse link
G G6PC1 glucose-6-phosphatase catalytic subunit 1 multiple interactions ISO Phlorhizin inhibits the reaction [Streptozocin results in increased expression of G6PC1 mRNA] CTD PMID:12446591 NCBI chr17:42,900,799...42,914,438
Ensembl chr17:42,900,797...42,914,438 		JBrowse link
G GCLC glutamate-cysteine ligase catalytic subunit decreases expression ISO Phlorhizin results in decreased expression of GCLC mRNA CTD PMID:22538082 NCBI chr 6:53,497,341...53,545,101
Ensembl chr 6:53,497,341...53,616,970 		JBrowse link
G GCLM glutamate-cysteine ligase modifier subunit decreases expression ISO Phlorhizin results in decreased expression of GCLM mRNA CTD PMID:22538082 NCBI chr 1:93,885,199...93,909,430
Ensembl chr 1:93,885,199...93,909,456 		JBrowse link
G GLRX2 glutaredoxin 2 decreases expression ISO Phlorhizin results in decreased expression of GLRX2 mRNA CTD PMID:22538082 NCBI chr 1:193,096,465...193,106,114
Ensembl chr 1:193,090,866...193,106,114 		JBrowse link
G GPD2 glycerol-3-phosphate dehydrogenase 2 increases expression
decreases expression		 ISO Phlorhizin results in increased expression of GPD2 mRNA
Phlorhizin results in decreased expression of GPD2 mRNA		 CTD PMID:16123366 PMID:22538082 NCBI chr 2:156,400,281...156,586,403
Ensembl chr 2:156,435,290...156,613,735 		JBrowse link
G GPX1 glutathione peroxidase 1 decreases expression ISO Phlorhizin results in decreased expression of GPX1 mRNA CTD PMID:16123366 NCBI chr 3:49,357,176...49,358,353
Ensembl chr 3:49,357,174...49,358,605 		JBrowse link
G GPX7 glutathione peroxidase 7 increases expression ISO Phlorhizin results in increased expression of GPX7 mRNA CTD PMID:22538082 NCBI chr 1:52,602,371...52,609,051
Ensembl chr 1:52,602,371...52,609,051 		JBrowse link
G GSTA5 glutathione S-transferase alpha 5 decreases expression ISO Phlorhizin results in decreased expression of GSTA5 mRNA CTD PMID:22538082 NCBI chr 6:52,831,692...52,846,245
Ensembl chr 6:52,831,655...52,840,843 		JBrowse link
G GSTK1 glutathione S-transferase kappa 1 decreases expression ISO Phlorhizin results in decreased expression of GSTK1 mRNA CTD PMID:22538082 NCBI chr 7:143,263,441...143,269,115
Ensembl chr 7:143,244,093...143,270,854 		JBrowse link
G GSTM1 glutathione S-transferase mu 1 decreases expression
increases expression		 ISO Phlorhizin results in decreased expression of GSTM1 mRNA; Phlorhizin results in decreased expression of GSTM5 mRNA
Phlorhizin results in increased expression of GSTM5 mRNA		 CTD PMID:22538082 NCBI chr 1:109,687,817...109,693,745
Ensembl chr 1:109,687,814...109,709,039 		JBrowse link
G GSTM2 glutathione S-transferase mu 2 increases expression ISO Phlorhizin results in increased expression of GSTM2 mRNA CTD PMID:22538082 NCBI chr 1:109,668,057...109,683,997
Ensembl chr 1:109,668,022...109,709,551 		JBrowse link
G GSTM4 glutathione S-transferase mu 4 increases expression ISO Phlorhizin results in increased expression of GSTM4 mRNA CTD PMID:22538082 NCBI chr 1:109,656,099...109,667,727
Ensembl chr 1:109,656,099...109,665,496 		JBrowse link
G GSTP1 glutathione S-transferase pi 1 increases expression ISO Phlorhizin results in increased expression of GSTP1 mRNA CTD PMID:22538082 NCBI chr11:67,583,812...67,586,653
Ensembl chr11:67,583,742...67,586,656 		JBrowse link
G GSTT1 glutathione S-transferase theta 1 decreases expression
increases expression		 ISO Phlorhizin results in decreased expression of GSTT1 mRNA
Phlorhizin results in increased expression of GSTT1 mRNA		 CTD PMID:22538082
G GSTT2B glutathione S-transferase theta 2B decreases expression ISO Phlorhizin results in decreased expression of GSTT2B mRNA CTD PMID:22538082 NCBI chr22:23,957,414...23,961,206
Ensembl chr22:23,957,414...23,961,195 		JBrowse link
G HACD3 3-hydroxyacyl-CoA dehydratase 3 decreases expression ISO Phlorhizin results in decreased expression of HACD3 mRNA CTD PMID:22538082 NCBI chr15:65,530,463...65,578,349
Ensembl chr15:65,530,418...65,578,349 		JBrowse link
G HADHB hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta increases expression ISO Phlorhizin results in increased expression of HADHB mRNA CTD PMID:22538082 NCBI chr 2:26,244,939...26,290,465
Ensembl chr 2:26,243,170...26,290,465 		JBrowse link
G HERPUD1 homocysteine inducible ER protein with ubiquitin like domain 1 decreases expression ISO Phlorhizin results in decreased expression of HERPUD1 mRNA CTD PMID:22538082 NCBI chr16:56,932,142...56,944,864
Ensembl chr16:56,932,142...56,944,864 		JBrowse link
G HIBADH 3-hydroxyisobutyrate dehydrogenase decreases expression ISO Phlorhizin results in decreased expression of HIBADH mRNA CTD PMID:22538082 NCBI chr 7:27,525,442...27,662,883
Ensembl chr 7:27,525,442...27,662,883 		JBrowse link
G HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 decreases expression ISO Phlorhizin results in decreased expression of HMGCS1 mRNA CTD PMID:22538082 NCBI chr 5:43,287,470...43,313,412
Ensembl chr 5:43,287,470...43,313,512 		JBrowse link
G HMOX1 heme oxygenase 1 decreases expression ISO Phlorhizin results in decreased expression of HMOX1 mRNA CTD PMID:16123366 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214 		JBrowse link
G HRAS HRas proto-oncogene, GTPase increases expression ISO Phlorhizin results in increased expression of HRAS mRNA CTD PMID:22538082 NCBI chr11:532,242...535,576
Ensembl chr11:532,242...537,321 		JBrowse link
G HSD17B10 hydroxysteroid 17-beta dehydrogenase 10 decreases expression ISO Phlorhizin results in decreased expression of HSD17B10 mRNA CTD PMID:22538082 NCBI chr  X:53,431,258...53,434,376
Ensembl chr  X:53,431,258...53,434,370 		JBrowse link
G HSD17B4 hydroxysteroid 17-beta dehydrogenase 4 decreases expression ISO Phlorhizin results in decreased expression of HSD17B4 mRNA CTD PMID:22538082 NCBI chr 5:119,452,497...119,542,332
Ensembl chr 5:119,452,465...119,637,199 		JBrowse link
G HSP90AA1 heat shock protein 90 alpha family class A member 1 decreases expression ISO Phlorhizin results in decreased expression of HSP90AA1 mRNA CTD PMID:22538082 NCBI chr14:102,080,742...102,139,749
Ensembl chr14:102,080,742...102,139,699 		JBrowse link
G HSP90AB1 heat shock protein 90 alpha family class B member 1 decreases expression ISO Phlorhizin results in decreased expression of HSP90AB1 mRNA CTD PMID:22538082 NCBI chr 6:44,246,194...44,253,883
Ensembl chr 6:44,246,166...44,253,888 		JBrowse link
G HSPA13 heat shock protein family A (Hsp70) member 13 decreases expression ISO Phlorhizin results in decreased expression of HSPA13 mRNA CTD PMID:22538082 NCBI chr21:14,371,115...14,383,146
Ensembl chr21:14,371,115...14,383,484 		JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 increases expression ISO Phlorhizin results in increased expression of HSPA5 mRNA CTD PMID:22538082 NCBI chr 9:125,234,853...125,241,343
Ensembl chr 9:125,234,853...125,241,382 		JBrowse link
G HSPA8 heat shock protein family A (Hsp70) member 8 increases expression ISO Phlorhizin results in increased expression of HSPA8 mRNA CTD PMID:22538082 NCBI chr11:123,057,489...123,062,462
Ensembl chr11:123,057,489...123,063,230 		JBrowse link
G HSPA9 heat shock protein family A (Hsp70) member 9 decreases expression ISO Phlorhizin results in decreased expression of HSPA9 mRNA CTD PMID:22538082 NCBI chr 5:138,553,756...138,575,401
Ensembl chr 5:138,553,756...138,575,675 		JBrowse link
G HSPB1 heat shock protein family B (small) member 1 increases expression ISO Phlorhizin results in increased expression of HSPB1 mRNA CTD PMID:22538082 NCBI chr 7:76,302,673...76,304,292
Ensembl chr 7:76,302,673...76,304,295 		JBrowse link
G HSPB8 heat shock protein family B (small) member 8 decreases expression ISO Phlorhizin results in decreased expression of HSPB8 mRNA CTD PMID:22538082 NCBI chr12:119,178,931...119,194,746
Ensembl chr12:119,171,555...119,224,855 		JBrowse link
G HSPD1 heat shock protein family D (Hsp60) member 1 decreases expression ISO Phlorhizin results in decreased expression of HSPD1 mRNA CTD PMID:22538082 NCBI chr 2:197,486,584...197,500,274
Ensembl chr 2:197,486,584...197,516,737 		JBrowse link
G HSPE1 heat shock protein family E (Hsp10) member 1 decreases expression ISO Phlorhizin results in decreased expression of HSPE1 mRNA CTD PMID:22538082 NCBI chr 2:197,500,379...197,503,449
Ensembl chr 2:197,500,140...197,503,449 		JBrowse link
G HTRA2 HtrA serine peptidase 2 decreases expression ISO Phlorhizin results in decreased expression of HTRA2 mRNA CTD PMID:22538082 NCBI chr 2:74,529,405...74,533,556
Ensembl chr 2:74,529,596...74,533,350 		JBrowse link
G ID1 inhibitor of DNA binding 1 decreases expression ISO Phlorhizin results in decreased expression of ID1 mRNA CTD PMID:16123366 NCBI chr20:31,605,289...31,606,510
Ensembl chr20:31,605,283...31,606,515 		JBrowse link
G IDH2 isocitrate dehydrogenase (NADP(+)) 2 increases expression ISO Phlorhizin results in increased expression of IDH2 mRNA CTD PMID:22538082 NCBI chr15:90,083,045...90,102,468
Ensembl chr15:90,083,045...90,102,477 		JBrowse link
G IDH3A isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha decreases expression ISO Phlorhizin results in decreased expression of IDH3A mRNA CTD PMID:22538082 NCBI chr15:78,149,362...78,171,945
Ensembl chr15:78,131,498...78,171,945 		JBrowse link
G IDH3B isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta decreases expression ISO Phlorhizin results in decreased expression of IDH3B mRNA CTD PMID:22538082 NCBI chr20:2,658,395...2,664,216
Ensembl chr20:2,658,395...2,664,219 		JBrowse link
G IDH3G isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit gamma decreases expression ISO Phlorhizin results in decreased expression of IDH3G mRNA CTD PMID:22538082 NCBI chr  X:153,785,768...153,794,375
Ensembl chr  X:153,785,766...153,794,512 		JBrowse link
G IL1B interleukin 1 beta multiple interactions ISO 2,2-bis(4-glycidyloxyphenyl)propane affects the reaction [[cobaltous chloride co-treated with Phlorhizin] affects the expression of IL1B mRNA]; [cobaltous chloride co-treated with Phlorhizin] affects the expression of IL1B mRNA; [lipopolysaccharide, E coli O55-B5 co-treated with Phlorhizin] affects the expression of IL1B mRNA CTD PMID:32408695 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL6 interleukin 6 multiple interactions ISO 2,2-bis(4-glycidyloxyphenyl)propane affects the reaction [[cobaltous chloride co-treated with Phlorhizin] affects the expression of IL6 mRNA]; 2,2-bis(4-glycidyloxyphenyl)propane affects the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Phlorhizin] affects the expression of IL6 mRNA]; [cobaltous chloride co-treated with Phlorhizin] affects the expression of IL6 mRNA; [lipopolysaccharide, E coli O55-B5 co-treated with Phlorhizin] affects the expression of IL6 mRNA CTD PMID:32408695 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G IVD isovaleryl-CoA dehydrogenase decreases expression ISO Phlorhizin results in decreased expression of IVD mRNA CTD PMID:22538082 NCBI chr15:40,405,795...40,435,947
Ensembl chr15:40,405,485...40,435,947 		JBrowse link
G JUNB JunB proto-oncogene, AP-1 transcription factor subunit decreases expression ISO Phlorhizin results in decreased expression of JUNB mRNA CTD PMID:22538082 NCBI chr19:12,791,486...12,793,315
Ensembl chr19:12,791,486...12,793,315 		JBrowse link
G JUND JunD proto-oncogene, AP-1 transcription factor subunit increases expression ISO Phlorhizin results in increased expression of JUND mRNA CTD PMID:22538082 NCBI chr19:18,279,694...18,281,622
Ensembl chr19:18,279,694...18,281,622 		JBrowse link
G KCNJ11 potassium inwardly rectifying channel subfamily J member 11 increases expression ISO Phlorhizin results in increased expression of KCNJ11 mRNA CTD PMID:16123366 NCBI chr11:17,385,248...17,389,346
Ensembl chr11:17,365,172...17,389,331 		JBrowse link
G KEAP1 kelch like ECH associated protein 1 increases expression ISO Phlorhizin results in increased expression of KEAP1 mRNA CTD PMID:22538082 NCBI chr19:10,486,125...10,503,356
Ensembl chr19:10,486,125...10,503,558 		JBrowse link
G KRAS KRAS proto-oncogene, GTPase decreases expression ISO Phlorhizin results in decreased expression of KRAS mRNA CTD PMID:22538082 NCBI chr12:25,205,246...25,250,929
Ensembl chr12:25,205,246...25,250,936 		JBrowse link
G LEP leptin multiple interactions ISO 2,2-bis(4-glycidyloxyphenyl)propane affects the reaction [[cobaltous chloride co-treated with Phlorhizin] affects the expression of LEP mRNA]; [2,2-bis(4-glycidyloxyphenyl)propane co-treated with lipopolysaccharide, E coli O55-B5 co-treated with Phlorhizin] affects the expression of LEP mRNA; [cobaltous chloride co-treated with Phlorhizin] affects the expression of LEP mRNA CTD PMID:32408695 NCBI chr 7:128,241,278...128,257,629
Ensembl chr 7:128,241,278...128,257,629 		JBrowse link
G MAF MAF bZIP transcription factor decreases expression ISO Phlorhizin results in decreased expression of MAF mRNA CTD PMID:22538082 NCBI chr16:79,202,622...79,600,737
Ensembl chr16:79,585,843...79,600,737 		JBrowse link
G MAFG MAF bZIP transcription factor G decreases expression ISO Phlorhizin results in decreased expression of MAFG mRNA CTD PMID:22538082 NCBI chr17:81,918,270...81,931,244
Ensembl chr17:81,918,270...81,927,735 		JBrowse link
G MAOB monoamine oxidase B decreases expression ISO Phlorhizin results in decreased expression of MAOB mRNA CTD PMID:22538082 NCBI chr  X:43,766,610...43,882,450
Ensembl chr  X:43,766,610...43,882,450 		JBrowse link
G MAP2K2 mitogen-activated protein kinase kinase 2 increases expression ISO Phlorhizin results in increased expression of MAP2K2 mRNA CTD PMID:22538082 NCBI chr19:4,090,321...4,124,122
Ensembl chr19:4,090,321...4,124,122 		JBrowse link
G MAP2K6 mitogen-activated protein kinase kinase 6 increases expression ISO Phlorhizin results in increased expression of MAP2K6 mRNA CTD PMID:22538082 NCBI chr17:69,414,697...69,553,865
Ensembl chr17:69,414,697...69,553,865 		JBrowse link
G MAP2K7 mitogen-activated protein kinase kinase 7 increases expression ISO Phlorhizin results in increased expression of MAP2K7 mRNA CTD PMID:22538082 NCBI chr19:7,903,877...7,914,478
Ensembl chr19:7,903,843...7,914,478 		JBrowse link
G MAP3K7 mitogen-activated protein kinase kinase kinase 7 decreases expression ISO Phlorhizin results in decreased expression of MAP3K7 mRNA CTD PMID:22538082 NCBI chr 6:90,513,579...90,587,072
Ensembl chr 6:90,513,573...90,587,086 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 increases expression ISO Phlorhizin results in increased expression of MAPK3 mRNA CTD PMID:22538082 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506 		JBrowse link
G MAPK9 mitogen-activated protein kinase 9 decreases expression ISO Phlorhizin results in decreased expression of MAPK9 mRNA CTD PMID:22538082 NCBI chr 5:180,233,143...180,292,083
Ensembl chr 5:180,233,143...180,292,099 		JBrowse link
G MCCC2 methylcrotonyl-CoA carboxylase subunit 2 decreases expression ISO Phlorhizin results in decreased expression of MCCC2 mRNA CTD PMID:22538082 NCBI chr 5:71,587,340...71,658,706
Ensembl chr 5:71,579,531...71,658,706 		JBrowse link
G MDM2 MDM2 proto-oncogene decreases expression ISO Phlorhizin results in decreased expression of MDM2 mRNA CTD PMID:22538082 NCBI chr12:68,808,172...68,850,686
Ensembl chr12:68,808,177...68,845,544 		JBrowse link
G MED20 mediator complex subunit 20 decreases expression ISO Phlorhizin results in decreased expression of MED20 mRNA CTD PMID:22538082 NCBI chr 6:41,905,354...41,921,139
Ensembl chr 6:41,905,354...41,921,139 		JBrowse link
G MGST1 microsomal glutathione S-transferase 1 increases expression ISO Phlorhizin results in increased expression of MGST1 mRNA CTD PMID:22538082 NCBI chr12:16,347,115...16,593,331
Ensembl chr12:16,347,142...16,609,259 		JBrowse link
G MMUT methylmalonyl-CoA mutase decreases expression ISO Phlorhizin results in decreased expression of MMUT mRNA CTD PMID:22538082 NCBI chr 6:49,430,360...49,463,253
Ensembl chr 6:49,430,360...49,463,253 		JBrowse link
G MYL9 myosin light chain 9 decreases phosphorylation ISO Phlorhizin results in decreased phosphorylation of MYL9 protein CTD PMID:17272349 NCBI chr20:36,541,519...36,551,447
Ensembl chr20:36,541,497...36,551,447 		JBrowse link
G NDUFA12 NADH:ubiquinone oxidoreductase subunit A12 increases expression ISO Phlorhizin results in increased expression of NDUFA12 mRNA CTD PMID:22538082 NCBI chr12:94,971,333...95,003,697
Ensembl chr12:94,895,297...95,003,748 		JBrowse link
G NDUFA2 NADH:ubiquinone oxidoreductase subunit A2 increases expression ISO Phlorhizin results in increased expression of NDUFA2 mRNA CTD PMID:22538082 NCBI chr 5:140,645,285...140,647,630
Ensembl chr 5:140,638,740...140,647,771 		JBrowse link
G NDUFA3 NADH:ubiquinone oxidoreductase subunit A3 decreases expression ISO Phlorhizin results in decreased expression of NDUFA3 mRNA CTD PMID:22538082 NCBI chr19:54,102,855...54,107,568
Ensembl chr19:54,102,728...54,109,257 		JBrowse link
G NDUFA7 NADH:ubiquinone oxidoreductase subunit A7 increases expression ISO Phlorhizin results in increased expression of NDUFA7 mRNA CTD PMID:22538082 NCBI chr19:8,308,595...8,321,375
Ensembl chr19:8,308,768...8,321,375 		JBrowse link
G NDUFAB1 NADH:ubiquinone oxidoreductase subunit AB1 increases expression ISO Phlorhizin results in increased expression of NDUFAB1 mRNA CTD PMID:22538082 NCBI chr16:23,581,014...23,596,316
Ensembl chr16:23,581,014...23,596,316 		JBrowse link
G NDUFAF1 NADH:ubiquinone oxidoreductase complex assembly factor 1 decreases expression ISO Phlorhizin results in decreased expression of NDUFAF1 mRNA CTD PMID:22538082 NCBI chr15:41,387,353...41,403,026
Ensembl chr15:41,387,218...41,409,403 		JBrowse link
G NDUFB6 NADH:ubiquinone oxidoreductase subunit B6 decreases expression ISO Phlorhizin results in decreased expression of NDUFB6 mRNA CTD PMID:22538082 NCBI chr 9:32,553,001...32,573,159
Ensembl chr 9:32,553,001...32,573,184 		JBrowse link
G NDUFS1 NADH:ubiquinone oxidoreductase core subunit S1 decreases expression ISO Phlorhizin results in decreased expression of NDUFS1 mRNA CTD PMID:22538082 NCBI chr 2:206,114,817...206,159,444
Ensembl chr 2:206,114,817...206,159,509 		JBrowse link
G NDUFS4 NADH:ubiquinone oxidoreductase subunit S4 decreases expression ISO Phlorhizin results in decreased expression of NDUFS4 mRNA CTD PMID:22538082 NCBI chr 5:53,560,639...53,683,338
Ensembl chr 5:53,560,633...53,683,338 		JBrowse link
G NDUFS5 NADH:ubiquinone oxidoreductase subunit S5 decreases expression ISO Phlorhizin results in decreased expression of NDUFS5 mRNA CTD PMID:22538082 NCBI chr 1:39,026,350...39,034,615
Ensembl chr 1:39,026,318...39,034,636 		JBrowse link
G NDUFS8 NADH:ubiquinone oxidoreductase core subunit S8 increases expression ISO Phlorhizin results in increased expression of NDUFS8 mRNA CTD PMID:22538082 NCBI chr11:68,030,681...68,036,644
Ensembl chr11:68,030,617...68,036,644 		JBrowse link
G NEDD4 NEDD4 E3 ubiquitin protein ligase decreases expression ISO Phlorhizin results in decreased expression of NEDD4 mRNA CTD PMID:22538082 NCBI chr15:55,826,917...55,993,612
Ensembl chr15:55,826,922...55,993,660 		JBrowse link
G NEUROD1 neuronal differentiation 1 increases expression ISO Phlorhizin results in increased expression of NEUROD1 mRNA CTD PMID:16123366 NCBI chr 2:181,668,295...181,680,517
Ensembl chr 2:181,668,295...181,680,827 		JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 decreases expression ISO Phlorhizin results in decreased expression of NFE2L2 mRNA CTD PMID:22538082 NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756 		JBrowse link
G NFKB1 nuclear factor kappa B subunit 1 multiple interactions ISO [Phlorhizin co-treated with 2,2-bis(4-glycidyloxyphenyl)propane co-treated with cobaltous chloride] affects the expression of NFKB1 mRNA CTD PMID:32408695 NCBI chr 4:102,501,359...102,617,302
Ensembl chr 4:102,501,330...102,617,302 		JBrowse link
G NKX6-1 NK6 homeobox 1 increases expression ISO Phlorhizin results in increased expression of NKX6-1 mRNA CTD PMID:16123366 NCBI chr 4:84,491,985...84,499,292
Ensembl chr 4:84,491,985...84,499,292 		JBrowse link
G NOS3 nitric oxide synthase 3 multiple interactions
decreases expression		 EXP Phlorhizin inhibits the reaction [Hydrogen Peroxide results in increased expression of NOS3 mRNA]
Phlorhizin results in decreased expression of NOS3 mRNA		 CTD PMID:20021702 NCBI chr 7:150,991,017...151,014,588
Ensembl chr 7:150,991,017...151,014,588 		JBrowse link
G NRAS NRAS proto-oncogene, GTPase decreases expression ISO Phlorhizin results in decreased expression of NRAS mRNA CTD PMID:22538082 NCBI chr 1:114,704,469...114,716,771
Ensembl chr 1:114,704,469...114,716,771 		JBrowse link
G OGDH oxoglutarate dehydrogenase decreases expression ISO Phlorhizin results in decreased expression of OGDH mRNA CTD PMID:22538082 NCBI chr 7:44,606,627...44,709,066
Ensembl chr 7:44,606,572...44,709,066 		JBrowse link
G PARK7 Parkinsonism associated deglycase increases expression ISO Phlorhizin results in increased expression of PARK7 mRNA CTD PMID:22538082 NCBI chr 1:7,961,711...7,985,505
Ensembl chr 1:7,954,291...7,985,505 		JBrowse link
G PC pyruvate carboxylase increases expression
decreases expression		 ISO Phlorhizin results in increased expression of PCX mRNA
Phlorhizin results in decreased expression of PC mRNA		 CTD PMID:16123366 PMID:22538082 NCBI chr11:66,848,420...66,958,383
Ensembl chr11:66,848,417...66,958,386 		JBrowse link
G PCCA propionyl-CoA carboxylase subunit alpha decreases expression ISO Phlorhizin results in decreased expression of PCCA mRNA CTD PMID:22538082 NCBI chr13:100,089,093...100,530,435
Ensembl chr13:100,089,015...100,530,437 		JBrowse link
G PCK1 phosphoenolpyruvate carboxykinase 1 decreases expression ISO Phlorhizin results in decreased expression of PCK1 mRNA CTD PMID:22538082 NCBI chr20:57,561,110...57,568,121
Ensembl chr20:57,561,080...57,568,121 		JBrowse link
G PECR peroxisomal trans-2-enoyl-CoA reductase increases expression
decreases expression		 ISO Phlorhizin results in increased expression of PECR mRNA
Phlorhizin results in decreased expression of PECR mRNA		 CTD PMID:22538082 NCBI chr 2:216,029,088...216,081,809
Ensembl chr 2:215,996,329...216,082,955 		JBrowse link
G PIK3C2A phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha decreases expression ISO Phlorhizin results in decreased expression of PIK3C2A mRNA CTD PMID:22538082 NCBI chr11:17,086,575...17,207,986
Ensembl chr11:17,077,730...17,207,986 		JBrowse link
G PIK3C3 phosphatidylinositol 3-kinase catalytic subunit type 3 decreases expression ISO Phlorhizin results in decreased expression of PIK3C3 mRNA CTD PMID:22538082 NCBI chr18:41,955,234...42,087,830
Ensembl chr18:41,955,234...42,087,830 		JBrowse link
G PINK1 PTEN induced kinase 1 increases expression ISO Phlorhizin results in increased expression of PINK1 mRNA CTD PMID:22538082 NCBI chr 1:20,633,458...20,651,511
Ensembl chr 1:20,633,458...20,651,511 		JBrowse link
G PRDX1 peroxiredoxin 1 increases expression ISO Phlorhizin results in increased expression of PRDX1 mRNA CTD PMID:22538082 NCBI chr 1:45,511,051...45,522,890
Ensembl chr 1:45,510,914...45,542,732 		JBrowse link
G PRDX5 peroxiredoxin 5 decreases expression ISO Phlorhizin results in decreased expression of PRDX5 mRNA CTD PMID:22538082 NCBI chr11:64,318,121...64,321,811
Ensembl chr11:64,318,121...64,321,811 		JBrowse link
G PRKCH protein kinase C eta increases expression ISO Phlorhizin results in increased expression of PRKCH mRNA CTD PMID:22538082 NCBI chr14:61,187,468...61,550,976
Ensembl chr14:61,187,559...61,550,976 		JBrowse link
G PRKCI protein kinase C iota decreases expression ISO Phlorhizin results in decreased expression of PRKCI mRNA CTD PMID:22538082 NCBI chr 3:170,222,424...170,305,977
Ensembl chr 3:170,222,424...170,305,977 		JBrowse link
G PRKD3 protein kinase D3 decreases expression ISO Phlorhizin results in decreased expression of PRKD3 mRNA CTD PMID:22538082 NCBI chr 2:37,250,502...37,324,833
Ensembl chr 2:37,250,502...37,324,833 		JBrowse link
G PSMA4 proteasome 20S subunit alpha 4 decreases expression ISO Phlorhizin results in decreased expression of PSMA4 mRNA CTD PMID:22538082 NCBI chr15:78,540,405...78,552,417
Ensembl chr15:78,540,405...78,552,417 		JBrowse link
G PSMB1 proteasome 20S subunit beta 1 increases expression ISO Phlorhizin results in increased expression of PSMB1 mRNA CTD PMID:22538082 NCBI chr 6:170,535,120...170,553,307
Ensembl chr 6:170,535,120...170,553,307 		JBrowse link
G PSMB2 proteasome 20S subunit beta 2 decreases expression ISO Phlorhizin results in decreased expression of PSMB2 mRNA CTD PMID:22538082 NCBI chr 1:35,599,541...35,641,526
Ensembl chr 1:35,599,541...35,641,526 		JBrowse link
G PSMC1 proteasome 26S subunit, ATPase 1 decreases expression ISO Phlorhizin results in decreased expression of PSMC1 mRNA CTD PMID:22538082 NCBI chr14:90,256,553...90,275,429
Ensembl chr14:90,256,527...90,275,429 		JBrowse link
G PSMC4 proteasome 26S subunit, ATPase 4 increases expression
decreases expression		 ISO Phlorhizin results in increased expression of PSMC4 mRNA
Phlorhizin results in decreased expression of PSMC4 mRNA		 CTD PMID:22538082 NCBI chr19:39,971,165...39,981,764
Ensembl chr19:39,971,165...39,981,764 		JBrowse link
G PSMC6 proteasome 26S subunit, ATPase 6 decreases expression ISO Phlorhizin results in decreased expression of PSMC6 mRNA CTD PMID:22538082 NCBI chr14:52,707,200...52,728,590
Ensembl chr14:52,707,178...52,728,590 		JBrowse link
G PSMD10 proteasome 26S subunit, non-ATPase 10 decreases expression ISO Phlorhizin results in decreased expression of PSMD10 mRNA CTD PMID:22538082 NCBI chr  X:108,084,207...108,091,542
Ensembl chr  X:108,084,207...108,091,549 		JBrowse link
G PSMD12 proteasome 26S subunit, non-ATPase 12 decreases expression ISO Phlorhizin results in decreased expression of PSMD12 mRNA CTD PMID:22538082 NCBI chr17:67,337,916...67,366,577
Ensembl chr17:67,337,916...67,366,605 		JBrowse link
G PSMD14 proteasome 26S subunit, non-ATPase 14 decreases expression ISO Phlorhizin results in decreased expression of PSMD14 mRNA CTD PMID:22538082 NCBI chr 2:161,308,425...161,411,717
Ensembl chr 2:161,308,425...161,411,717 		JBrowse link
G PSMD4 proteasome 26S subunit ubiquitin receptor, non-ATPase 4 decreases expression ISO Phlorhizin results in decreased expression of PSMD4 mRNA CTD PMID:22538082 NCBI chr 1:151,254,734...151,267,479
Ensembl chr 1:151,254,709...151,267,479 		JBrowse link
G PSMD6 proteasome 26S subunit, non-ATPase 6 increases expression ISO Phlorhizin results in increased expression of PSMD6 mRNA CTD PMID:22538082 NCBI chr 3:64,010,551...64,024,007
Ensembl chr 3:64,010,550...64,024,010 		JBrowse link
G PSMD7 proteasome 26S subunit, non-ATPase 7 decreases expression ISO Phlorhizin results in decreased expression of PSMD7 mRNA CTD PMID:22538082 NCBI chr16:74,296,814...74,306,288
Ensembl chr16:74,296,814...74,306,288 		JBrowse link
G PSMD9 proteasome 26S subunit, non-ATPase 9 decreases expression ISO Phlorhizin results in decreased expression of PSMD9 mRNA CTD PMID:22538082 NCBI chr12:121,888,790...121,918,297
Ensembl chr12:121,888,732...121,918,297 		JBrowse link
G RAF1 Raf-1 proto-oncogene, serine/threonine kinase decreases expression ISO Phlorhizin results in decreased expression of RAF1 mRNA CTD PMID:22538082 NCBI chr 3:12,583,601...12,664,117
Ensembl chr 3:12,582,101...12,664,201 		JBrowse link
G RDH14 retinol dehydrogenase 14 increases expression ISO Phlorhizin results in increased expression of RDH14 mRNA CTD PMID:22538082 NCBI chr 2:18,554,723...18,560,653
Ensembl chr 2:18,554,723...18,560,679 		JBrowse link
G S100A6 S100 calcium binding protein A6 decreases expression ISO Phlorhizin results in decreased expression of S100A6 mRNA CTD PMID:16123366 NCBI chr 1:153,534,599...153,535,991
Ensembl chr 1:153,534,599...153,536,244 		JBrowse link
G SDHA succinate dehydrogenase complex flavoprotein subunit A decreases expression ISO Phlorhizin results in decreased expression of SDHA mRNA CTD PMID:22538082 NCBI chr 5:218,320...268,746
Ensembl chr 5:218,303...257,082 		JBrowse link
G SDHB succinate dehydrogenase complex iron sulfur subunit B increases expression ISO Phlorhizin results in increased expression of SDHB mRNA CTD PMID:22538082 NCBI chr 1:17,018,722...17,054,032
Ensembl chr 1:17,018,664...17,054,151 		JBrowse link
G SDS serine dehydratase decreases expression ISO Phlorhizin results in decreased expression of SDS mRNA CTD PMID:22538082 NCBI chr12:113,392,445...113,403,887
Ensembl chr12:113,392,445...113,426,301 		JBrowse link
G SLC2A2 solute carrier family 2 member 2 increases expression ISO Phlorhizin results in increased expression of SLC2A2 mRNA CTD PMID:16123366 NCBI chr 3:170,996,347...171,026,720
Ensembl chr 3:170,996,347...171,026,743 		JBrowse link
G SLC35A2 solute carrier family 35 member A2 increases expression ISO Phlorhizin results in increased expression of SLC35A2 mRNA CTD PMID:22538082 NCBI chr  X:48,903,183...48,911,958
Ensembl chr  X:48,903,180...48,911,958 		JBrowse link
G SLC5A1 solute carrier family 5 member 1 multiple interactions
decreases activity
affects binding		 EXP
ISO		 Phlorhizin inhibits the reaction [[Sodium co-treated with SLC5A1 protein] results in increased uptake of methylglucoside]; Phlorhizin inhibits the reaction [SLC5A1 protein results in increased uptake of methylglucoside]
[Phlorhizin results in decreased activity of SLC5A1 protein] which results in decreased uptake of spiraeoside
[Phlorhizin results in decreased activity of SLC5A1 protein] which results in decreased uptake of Glucose
SLC5A1 protein binds to Phlorhizin		 CTD PMID:12663055 PMID:12927799 PMID:16300400 PMID:17288452 PMID:17983207 NCBI chr22:32,043,261...32,113,029
Ensembl chr22:32,043,261...32,113,029 		JBrowse link
G SLC5A2 solute carrier family 5 member 2 decreases activity EXP Phlorhizin results in decreased activity of SLC5A2 protein CTD PMID:21128592 NCBI chr16:31,483,123...31,490,769
Ensembl chr16:31,483,002...31,490,860 		JBrowse link
G SOD1 superoxide dismutase 1 increases expression ISO Phlorhizin results in increased expression of SOD1 mRNA CTD PMID:22538082 NCBI chr21:31,659,693...31,668,931
Ensembl chr21:31,659,666...31,668,931 		JBrowse link
G SOD2 superoxide dismutase 2 decreases expression ISO Phlorhizin results in decreased expression of SOD2 mRNA CTD PMID:22538082 NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529 		JBrowse link
G STIP1 stress induced phosphoprotein 1 decreases expression ISO Phlorhizin results in decreased expression of STIP1 mRNA CTD PMID:22538082 NCBI chr11:64,185,272...64,204,543
Ensembl chr11:64,185,272...64,204,543 		JBrowse link
G SUCLA2 succinate-CoA ligase ADP-forming subunit beta decreases expression ISO Phlorhizin results in decreased expression of SUCLA2 mRNA CTD PMID:22538082 NCBI chr13:47,942,656...48,001,273
Ensembl chr13:47,745,736...48,037,968 		JBrowse link
G SUCLG2 succinate-CoA ligase GDP-forming subunit beta decreases expression ISO Phlorhizin results in decreased expression of SUCLG2 mRNA CTD PMID:22538082 NCBI chr 3:67,360,460...67,654,612
Ensembl chr 3:67,360,460...67,654,612 		JBrowse link
G SUGT1 SGT1 homolog, MIS12 kinetochore complex assembly cochaperone decreases expression ISO Phlorhizin results in decreased expression of SUGT1 mRNA CTD PMID:22538082 NCBI chr13:52,652,836...52,700,909
Ensembl chr13:52,652,709...52,700,909 		JBrowse link
G TXN thioredoxin decreases expression
increases expression		 ISO Phlorhizin results in decreased expression of TXN mRNA
Phlorhizin results in increased expression of TXN mRNA		 CTD PMID:22538082 NCBI chr 9:110,243,810...110,256,507
Ensembl chr 9:110,243,810...110,256,507 		JBrowse link
G TXN2 thioredoxin 2 increases expression ISO Phlorhizin results in increased expression of TXN2 mRNA CTD PMID:22538082 NCBI chr22:36,467,046...36,481,640
Ensembl chr22:36,467,046...36,481,640 		JBrowse link
G UBB ubiquitin B increases expression ISO Phlorhizin results in increased expression of UBB mRNA CTD PMID:22538082 NCBI chr17:16,380,779...16,382,745
Ensembl chr17:16,380,798...16,382,745 		JBrowse link
G UBC ubiquitin C decreases expression ISO Phlorhizin results in decreased expression of UBC mRNA CTD PMID:22538082 NCBI chr12:124,911,646...124,914,650
Ensembl chr12:124,911,604...124,917,368 		JBrowse link
G UBE2B ubiquitin conjugating enzyme E2 B decreases expression ISO Phlorhizin results in decreased expression of UBE2B mRNA CTD PMID:22538082 NCBI chr 5:134,371,569...134,392,108
Ensembl chr 5:134,371,184...134,392,108 		JBrowse link
G UBE2F ubiquitin conjugating enzyme E2 F (putative) decreases expression ISO Phlorhizin results in decreased expression of UBE2F mRNA CTD PMID:22538082 NCBI chr 2:237,967,014...238,042,782
Ensembl chr 2:237,966,827...238,042,782 		JBrowse link
G UBE2H ubiquitin conjugating enzyme E2 H decreases expression ISO Phlorhizin results in decreased expression of UBE2H mRNA CTD PMID:22538082 NCBI chr 7:129,830,732...129,952,960
Ensembl chr 7:129,830,732...129,952,960 		JBrowse link
G UBE2I ubiquitin conjugating enzyme E2 I decreases expression ISO Phlorhizin results in decreased expression of UBE2I mRNA CTD PMID:22538082 NCBI chr16:1,309,152...1,327,017
Ensembl chr16:1,291,444...1,327,018 		JBrowse link
G UBE2L3 ubiquitin conjugating enzyme E2 L3 decreases expression ISO Phlorhizin results in decreased expression of UBE2L3 mRNA CTD PMID:22538082 NCBI chr22:21,549,447...21,624,034
Ensembl chr22:21,549,447...21,624,034 		JBrowse link
G UBE2M ubiquitin conjugating enzyme E2 M increases expression ISO Phlorhizin results in increased expression of UBE2M mRNA CTD PMID:22538082 NCBI chr19:58,555,712...58,558,611
Ensembl chr19:58,555,712...58,558,954 		JBrowse link
G UBE2N ubiquitin conjugating enzyme E2 N decreases expression ISO Phlorhizin results in decreased expression of UBE2N mRNA CTD PMID:22538082 NCBI chr12:93,405,684...93,441,947
Ensembl chr12:93,405,673...93,441,947 		JBrowse link
G UBE2Q1 ubiquitin conjugating enzyme E2 Q1 increases expression ISO Phlorhizin results in increased expression of UBE2Q1 mRNA CTD PMID:22538082 NCBI chr 1:154,548,577...154,558,662
Ensembl chr 1:154,548,577...154,559,028 		JBrowse link
G UBE2R2 ubiquitin conjugating enzyme E2 R2 decreases expression ISO Phlorhizin results in decreased expression of UBE2R2 mRNA CTD PMID:22538082 NCBI chr 9:33,815,168...33,920,399
Ensembl chr 9:33,817,160...33,920,399 		JBrowse link
G UBE2V2 ubiquitin conjugating enzyme E2 V2 decreases expression ISO Phlorhizin results in decreased expression of UBE2V2 mRNA CTD PMID:22538082 NCBI chr 8:47,997,437...48,064,708
Ensembl chr 8:48,008,415...48,064,708 		JBrowse link
G UBE4A ubiquitination factor E4A increases expression ISO Phlorhizin results in increased expression of UBE4A mRNA CTD PMID:22538082 NCBI chr11:118,359,600...118,399,211
Ensembl chr11:118,359,600...118,399,211 		JBrowse link
G UBR2 ubiquitin protein ligase E3 component n-recognin 2 increases expression ISO Phlorhizin results in increased expression of UBR2 mRNA CTD PMID:22538082 NCBI chr 6:42,564,029...42,693,505
Ensembl chr 6:42,564,029...42,693,505 		JBrowse link
G UCHL3 ubiquitin C-terminal hydrolase L3 decreases expression ISO Phlorhizin results in decreased expression of UCHL3 mRNA CTD PMID:22538082 NCBI chr13:75,549,502...75,606,020
Ensembl chr13:75,549,483...75,606,020 		JBrowse link
G UCHL5 ubiquitin C-terminal hydrolase L5 decreases expression ISO Phlorhizin results in decreased expression of UCHL5 mRNA CTD PMID:22538082 NCBI chr 1:193,012,254...193,060,076
Ensembl chr 1:193,012,250...193,060,080 		JBrowse link
G UGT1A1 UDP glucuronosyltransferase family 1 member A1 decreases activity EXP Phlorhizin results in decreased activity of UGT1A1 protein CTD PMID:35868516 NCBI chr 2:233,760,270...233,773,300
Ensembl chr 2:233,760,270...233,773,300 		JBrowse link
G UGT1A10 UDP glucuronosyltransferase family 1 member A10 decreases activity EXP Phlorhizin results in decreased activity of UGT1A10 protein CTD PMID:35868516 NCBI chr 2:233,636,448...233,773,300
Ensembl chr 2:233,636,448...233,773,300 		JBrowse link
G UGT1A3 UDP glucuronosyltransferase family 1 member A3 decreases activity EXP Phlorhizin results in decreased activity of UGT1A3 protein CTD PMID:35868516 NCBI chr 2:233,729,042...233,773,300
Ensembl chr 2:233,729,042...233,773,300 		JBrowse link
G UGT1A7 UDP glucuronosyltransferase family 1 member A7 decreases activity EXP Phlorhizin results in decreased activity of UGT1A7 protein CTD PMID:35868516 NCBI chr 2:233,681,901...233,773,300
Ensembl chr 2:233,681,901...233,773,300 		JBrowse link
G UGT1A8 UDP glucuronosyltransferase family 1 member A8 decreases activity EXP Phlorhizin results in decreased activity of UGT1A8 protein CTD PMID:35868516 NCBI chr 2:233,617,633...233,773,300
Ensembl chr 2:233,617,633...233,773,300 		JBrowse link
G UGT1A9 UDP glucuronosyltransferase family 1 member A9 decreases activity EXP Phlorhizin results in decreased activity of UGT1A9 protein CTD PMID:35868516 NCBI chr 2:233,671,898...233,773,300
Ensembl chr 2:233,671,898...233,773,300 		JBrowse link
G UGT2B15 UDP glucuronosyltransferase family 2 member B15 decreases activity EXP Phlorhizin results in decreased activity of UGT2B15 protein CTD PMID:35868516 NCBI chr 4:68,646,597...68,670,652
Ensembl chr 4:68,646,597...68,670,652 		JBrowse link
G UGT2B17 UDP glucuronosyltransferase family 2 member B17 decreases activity EXP Phlorhizin results in decreased activity of UGT2B17 protein CTD PMID:35868516 NCBI chr 4:68,537,173...68,576,322
Ensembl chr 4:68,537,173...68,576,413 		JBrowse link
G UGT2B4 UDP glucuronosyltransferase family 2 member B4 decreases activity EXP Phlorhizin results in decreased activity of UGT2B4 protein CTD PMID:35868516 NCBI chr 4:69,480,165...69,526,014
Ensembl chr 4:69,480,165...69,526,014 		JBrowse link
G UGT2B7 UDP glucuronosyltransferase family 2 member B7 decreases activity EXP Phlorhizin results in decreased activity of UGT2B7 protein CTD PMID:35868516 NCBI chr 4:69,051,375...69,112,987
Ensembl chr 4:69,051,363...69,112,987 		JBrowse link
G UQCRC2 ubiquinol-cytochrome c reductase core protein 2 decreases expression ISO Phlorhizin results in decreased expression of UQCRC2 mRNA CTD PMID:22538082 NCBI chr16:21,953,361...21,983,660
Ensembl chr16:21,953,288...21,983,660 		JBrowse link
G USP1 ubiquitin specific peptidase 1 increases expression ISO Phlorhizin results in increased expression of USP1 mRNA CTD PMID:22538082 NCBI chr 1:62,436,395...62,451,804
Ensembl chr 1:62,436,297...62,451,804 		JBrowse link
G USP14 ubiquitin specific peptidase 14 decreases expression ISO Phlorhizin results in decreased expression of USP14 mRNA CTD PMID:22538082 NCBI chr18:158,557...214,629
Ensembl chr18:158,383...214,629 		JBrowse link
G USP19 ubiquitin specific peptidase 19 increases expression ISO Phlorhizin results in increased expression of USP19 mRNA CTD PMID:22538082 NCBI chr 3:49,108,050...49,120,823
Ensembl chr 3:49,108,046...49,120,938 		JBrowse link
G USP24 ubiquitin specific peptidase 24 decreases expression ISO Phlorhizin results in decreased expression of USP24 mRNA CTD PMID:22538082 NCBI chr 1:55,066,359...55,215,364
Ensembl chr 1:55,066,359...55,215,378 		JBrowse link
G USP33 ubiquitin specific peptidase 33 decreases expression ISO Phlorhizin results in decreased expression of USP33 mRNA CTD PMID:22538082 NCBI chr 1:77,695,987...77,759,852
Ensembl chr 1:77,695,987...77,759,852 		JBrowse link
G USP4 ubiquitin specific peptidase 4 increases expression ISO Phlorhizin results in increased expression of USP4 mRNA CTD PMID:22538082 NCBI chr 3:49,277,144...49,340,053
Ensembl chr 3:49,277,144...49,340,712 		JBrowse link
G USP45 ubiquitin specific peptidase 45 decreases expression ISO Phlorhizin results in decreased expression of USP45 mRNA CTD PMID:22538082 NCBI chr 6:99,432,325...99,517,846
Ensembl chr 6:99,432,325...99,521,728 		JBrowse link
G USP46 ubiquitin specific peptidase 46 decreases expression ISO Phlorhizin results in decreased expression of USP46 mRNA CTD PMID:22538082 NCBI chr 4:52,590,960...52,659,301
Ensembl chr 4:52,590,960...52,659,301 		JBrowse link
G USP7 ubiquitin specific peptidase 7 decreases expression ISO Phlorhizin results in decreased expression of USP7 mRNA CTD PMID:22538082 NCBI chr16:8,892,097...8,963,906
Ensembl chr16:8,892,097...8,975,328 		JBrowse link
G USP9X ubiquitin specific peptidase 9 X-linked decreases expression ISO Phlorhizin results in decreased expression of USP9X mRNA CTD PMID:22538082 NCBI chr  X:41,085,445...41,236,579
Ensembl chr  X:41,085,445...41,236,579 		JBrowse link
G VEGFA vascular endothelial growth factor A multiple interactions ISO 2,2-bis(4-glycidyloxyphenyl)propane affects the reaction [[cobaltous chloride co-treated with lipopolysaccharide, E coli O55-B5 co-treated with Phlorhizin] results in increased expression of VEGFA mRNA]; 2,2-bis(4-glycidyloxyphenyl)propane affects the reaction [[cobaltous chloride co-treated with Phlorhizin] affects the expression of VEGFA mRNA]; [cobaltous chloride co-treated with lipopolysaccharide, E coli O55-B5 co-treated with Phlorhizin] results in increased expression of VEGFA mRNA; [cobaltous chloride co-treated with Phlorhizin] affects the expression of VEGFA mRNA CTD PMID:32408695 NCBI chr 6:43,770,211...43,786,487
Ensembl chr 6:43,770,184...43,786,487 		JBrowse link
G XIAP X-linked inhibitor of apoptosis decreases expression ISO Phlorhizin results in decreased expression of XIAP mRNA CTD PMID:22538082 NCBI chr  X:123,859,708...123,913,972
Ensembl chr  X:123,859,712...123,913,972 		JBrowse link
phlorizin chalcone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HMOX1 heme oxygenase 1 increases expression EXP isosalipurposide results in increased expression of HMOX1 protein CTD PMID:26028482 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 multiple interactions EXP MAPK1 protein affects the reaction [isosalipurposide affects the localization of NFE2L2 protein] CTD PMID:26028482 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 multiple interactions EXP MAPK3 protein affects the reaction [isosalipurposide affects the localization of NFE2L2 protein] CTD PMID:26028482 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506 		JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 affects localization
multiple interactions		 EXP isosalipurposide affects the localization of NFE2L2 protein
MAPK1 protein affects the reaction [isosalipurposide affects the localization of NFE2L2 protein]; MAPK3 protein affects the reaction [isosalipurposide affects the localization of NFE2L2 protein]		 CTD PMID:26028482 NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756 		JBrowse link
picrocrocin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TRPA1 transient receptor potential cation channel subfamily A member 1 multiple interactions
increases activity		 EXP 2-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)-N-(4-isopropylphenyl)acetamide inhibits the reaction [picrocrocin results in increased activity of TRPA1 protein] CTD PMID:30636360 NCBI chr 8:72,021,250...72,090,010
Ensembl chr 8:72,019,917...72,075,584 		JBrowse link
quercetin 3-O-beta-D-glucofuranoside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACAT2 acetyl-CoA acetyltransferase 2 multiple interactions EXP [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of ACAT2 mRNA CTD PMID:18032389 NCBI chr 6:159,762,045...159,779,112
Ensembl chr 6:159,762,045...159,779,112 		JBrowse link
G AKR7A3 aldo-keto reductase family 7 member A3 multiple interactions ISO [Diethylnitrosamine co-treated with oxfendazole co-treated with isoquercitrin] results in increased expression of AKR7A3 mRNA CTD PMID:20033131 NCBI chr 1:19,274,229...19,288,770
Ensembl chr 1:19,282,573...19,288,770 		JBrowse link
G APOA1 apolipoprotein A1 increases secretion EXP isoquercitrin results in increased secretion of APOA1 protein CTD PMID:24963805 NCBI chr11:116,835,751...116,837,950
Ensembl chr11:116,835,751...116,837,622 		JBrowse link
G ATF6 activating transcription factor 6 increases expression ISO isoquercitrin results in increased expression of ATF6 mRNA CTD PMID:30365939 NCBI chr 1:161,766,320...161,964,070
Ensembl chr 1:161,766,298...161,977,574 		JBrowse link
G ATXN2 ataxin 2 multiple interactions ISO isoquercitrin inhibits the reaction [Oxidopamine results in increased expression of ATXN2 mRNA] CTD PMID:25129099 NCBI chr12:111,452,214...111,599,673
Ensembl chr12:111,443,485...111,599,676 		JBrowse link
G ATXN3 ataxin 3 multiple interactions ISO isoquercitrin inhibits the reaction [Oxidopamine results in increased expression of ATXN3 mRNA] CTD PMID:25129099 NCBI chr14:92,044,775...92,106,582
Ensembl chr14:92,044,496...92,106,621 		JBrowse link
G BCL2 BCL2 apoptosis regulator decreases expression EXP isoquercitrin results in decreased expression of BCL2 mRNA CTD PMID:30597948 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128 		JBrowse link
G CASP3 caspase 3 affects expression EXP isoquercitrin affects the expression of CASP3 mRNA CTD PMID:30597948 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062 		JBrowse link
G CASP8 caspase 8 decreases expression EXP isoquercitrin results in decreased expression of CASP8 mRNA CTD PMID:30597948 NCBI chr 2:201,233,463...201,287,711
Ensembl chr 2:201,233,443...201,361,836 		JBrowse link
G CAT catalase multiple interactions ISO [Diethylnitrosamine co-treated with Dietary Fats co-treated with Canrenoic Acid co-treated with isoquercitrin analog] results in increased expression of CAT mRNA; isoquercitrin inhibits the reaction [Streptozocin results in decreased activity of CAT protein] CTD PMID:30298849 PMID:30817903 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060 		JBrowse link
G CCL2 C-C motif chemokine ligand 2 multiple interactions ISO isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CCL2 mRNA] CTD PMID:21295105 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208 		JBrowse link
G CCL5 C-C motif chemokine ligand 5 multiple interactions ISO isoquercitrin inhibits the reaction [Carrageenan results in increased expression of CCL5 protein] CTD PMID:14654164 NCBI chr17:35,871,491...35,880,360
Ensembl chr17:35,871,491...35,880,793 		JBrowse link
G CDKN2B cyclin dependent kinase inhibitor 2B multiple interactions ISO isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CDKN2B mRNA] CTD PMID:21295105 NCBI chr 9:22,002,903...22,009,313
Ensembl chr 9:22,002,903...22,009,305 		JBrowse link
G CTNNB1 catenin beta 1 affects expression EXP isoquercitrin affects the expression of CTNNB1 mRNA CTD PMID:30597948 NCBI chr 3:41,199,505...41,240,443
Ensembl chr 3:41,194,741...41,260,096 		JBrowse link
G CXCL2 C-X-C motif chemokine ligand 2 multiple interactions ISO isoquercitrin inhibits the reaction [Carrageenan results in increased expression of CXCL2 protein] CTD PMID:14654164 NCBI chr 4:74,097,040...74,099,195
Ensembl chr 4:74,097,040...74,099,196 		JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 increases expression EXP isoquercitrin results in increased expression of CXCL8 mRNA CTD PMID:30597948 NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716 		JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 multiple interactions
decreases activity		 ISO
EXP		 [Diethylnitrosamine co-treated with oxfendazole co-treated with isoquercitrin] results in increased expression of CYP1A1 mRNA
isoquercitrin results in decreased activity of CYP1A1 protein		 CTD PMID:16271822 PMID:20033131 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536 		JBrowse link
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 multiple interactions ISO [Diethylnitrosamine co-treated with oxfendazole co-treated with isoquercitrin] results in increased expression of CYP1A2 mRNA CTD PMID:20033131 NCBI chr15:74,748,845...74,756,607
Ensembl chr15:74,748,845...74,756,607 		JBrowse link
G CYP1B1 cytochrome P450 family 1 subfamily B member 1 decreases activity EXP isoquercitrin results in decreased activity of CYP1B1 protein CTD PMID:16271822 NCBI chr 2:38,067,509...38,076,151
Ensembl chr 2:38,066,973...38,109,902 		JBrowse link
G CYP51A1 cytochrome P450 family 51 subfamily A member 1 multiple interactions EXP [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of CYP51A1 mRNA CTD PMID:18032389 NCBI chr 7:92,112,153...92,134,803
Ensembl chr 7:92,084,987...92,134,803 		JBrowse link
G DHCR7 7-dehydrocholesterol reductase multiple interactions EXP [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of DHCR7 mRNA CTD PMID:18032389 NCBI chr11:71,434,411...71,448,393
Ensembl chr11:71,428,193...71,452,868 		JBrowse link
G EGF epidermal growth factor multiple interactions EXP isoquercitrin inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein]; isoquercitrin inhibits the reaction [EGF protein results in increased phosphorylation of MAPK1 protein]; isoquercitrin inhibits the reaction [EGF protein results in increased phosphorylation of MAPK3 protein]; isoquercitrin inhibits the reaction [EGF protein results in increased phosphorylation of PTK2 protein] CTD PMID:26109002 NCBI chr 4:109,912,883...110,013,766
Ensembl chr 4:109,912,883...110,013,766 		JBrowse link
G EGFR epidermal growth factor receptor multiple interactions EXP isoquercitrin inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein] CTD PMID:26109002 NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628 		JBrowse link
G EGLN1 egl-9 family hypoxia inducible factor 1 multiple interactions ISO isoquercitrin inhibits the reaction [Oxidopamine results in increased expression of EGLN1 mRNA] CTD PMID:25129099 NCBI chr 1:231,363,756...231,422,287
Ensembl chr 1:231,363,751...231,422,287 		JBrowse link
G FDFT1 farnesyl-diphosphate farnesyltransferase 1 multiple interactions EXP [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of FDFT1 mRNA CTD PMID:18032389 NCBI chr 8:11,795,582...11,839,309
Ensembl chr 8:11,795,573...11,839,395 		JBrowse link
G FDPS farnesyl diphosphate synthase multiple interactions EXP [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of FDPS mRNA CTD PMID:18032389 NCBI chr 1:155,308,866...155,320,665
Ensembl chr 1:155,308,748...155,320,666 		JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO [isoquercitrin analog co-treated with Propylthiouracil] results in decreased expression of FOS mRNA CTD PMID:31068541 NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,282,230 		JBrowse link
G GPX2 glutathione peroxidase 2 multiple interactions ISO [Diethylnitrosamine co-treated with oxfendazole co-treated with isoquercitrin] results in increased expression of GPX2 mRNA CTD PMID:20033131 NCBI chr14:64,939,158...64,942,745
Ensembl chr14:64,939,152...64,942,746 		JBrowse link
G GRIA3 glutamate ionotropic receptor AMPA type subunit 3 multiple interactions ISO isoquercitrin analog inhibits the reaction [Propylthiouracil results in increased expression of GRIA3 mRNA] CTD PMID:31068541 NCBI chr  X:123,184,278...123,490,915
Ensembl chr  X:123,184,153...123,490,915 		JBrowse link
G GSTA5 glutathione S-transferase alpha 5 multiple interactions ISO [isoquercitrin co-treated with oxfendazole co-treated with Diethylnitrosamine] results in increased expression of GSTA5 mRNA; isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of GSTA5 mRNA] CTD PMID:20033131 PMID:20045035 NCBI chr 6:52,831,692...52,846,245
Ensembl chr 6:52,831,655...52,840,843 		JBrowse link
G GSTM1 glutathione S-transferase mu 1 multiple interactions ISO [Diethylnitrosamine co-treated with oxfendazole co-treated with isoquercitrin] results in increased expression of GSTM1 mRNA; isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of GSTM1 mRNA] CTD PMID:20033131 PMID:20045035 NCBI chr 1:109,687,817...109,693,745
Ensembl chr 1:109,687,814...109,709,039 		JBrowse link
G HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase multiple interactions EXP [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of HMGCR mRNA CTD PMID:18032389 NCBI chr 5:75,336,529...75,362,116
Ensembl chr 5:75,336,329...75,364,001 		JBrowse link
G HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 multiple interactions EXP [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of HMGCS1 mRNA CTD PMID:18032389 NCBI chr 5:43,287,470...43,313,412
Ensembl chr 5:43,287,470...43,313,512 		JBrowse link
G HMOX1 heme oxygenase 1 multiple interactions ISO isoquercitrin inhibits the reaction [beta-Naphthoflavone results in increased expression of HMOX1 protein]; isoquercitrin inhibits the reaction [Streptozocin results in increased expression of HMOX1 mRNA] CTD PMID:21295105 PMID:30817903 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214 		JBrowse link
G IBSP integrin binding sialoprotein increases expression ISO isoquercitrin results in increased expression of IBSP mRNA CTD PMID:30365939 NCBI chr 4:87,799,554...87,812,435
Ensembl chr 4:87,799,554...87,812,435 		JBrowse link
G IL1A interleukin 1 alpha multiple interactions ISO [isoquercitrin analog co-treated with Propylthiouracil] results in increased expression of IL1A mRNA; [isoquercitrin co-treated with Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of IL1A mRNA CTD PMID:21295105 PMID:31068541 NCBI chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493 		JBrowse link
G IL1B interleukin 1 beta multiple interactions ISO isoquercitrin inhibits the reaction [Streptozocin results in increased expression of IL1B mRNA] CTD PMID:30817903 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL6 interleukin 6 multiple interactions ISO isoquercitrin inhibits the reaction [Streptozocin results in increased expression of IL6 mRNA] CTD PMID:30817903 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G INS-IGF2 INS-IGF2 readthrough multiple interactions ISO isoquercitrin inhibits the reaction [Streptozocin results in increased expression of INS1 protein] CTD PMID:30817903 NCBI chr11:2,129,117...2,161,209
Ensembl chr11:2,132,538...2,161,209 		JBrowse link
G INSIG1 insulin induced gene 1 multiple interactions EXP [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of INSIG1 mRNA CTD PMID:18032389 NCBI chr 7:155,297,878...155,310,235
Ensembl chr 7:155,297,776...155,310,235 		JBrowse link
G JAK1 Janus kinase 1 increases expression EXP isoquercitrin results in increased expression of JAK1 mRNA CTD PMID:30597948 NCBI chr 1:64,833,229...65,067,746
Ensembl chr 1:64,833,223...65,067,754 		JBrowse link
G JAK2 Janus kinase 2 increases expression EXP isoquercitrin results in increased expression of JAK2 mRNA CTD PMID:30597948 NCBI chr 9:4,984,390...5,129,948
Ensembl chr 9:4,984,390...5,129,948 		JBrowse link
G KEAP1 kelch like ECH associated protein 1 multiple interactions ISO isoquercitrin inhibits the reaction [Streptozocin results in decreased expression of KEAP1 mRNA] CTD PMID:30817903 NCBI chr19:10,486,125...10,503,356
Ensembl chr19:10,486,125...10,503,558 		JBrowse link
G LCT lactase multiple interactions ISO [migalastat results in decreased activity of LCT protein] which results in decreased hydrolysis of isoquercitrin CTD PMID:12663055 NCBI chr 2:135,787,850...135,837,184
Ensembl chr 2:135,787,850...135,837,184 		JBrowse link
G LDLR low density lipoprotein receptor multiple interactions EXP [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of LDLR mRNA CTD PMID:18032389 NCBI chr19:11,089,463...11,133,820
Ensembl chr19:11,089,418...11,133,820 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 multiple interactions EXP isoquercitrin inhibits the reaction [EGF protein results in increased phosphorylation of MAPK1 protein] CTD PMID:26109002 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 multiple interactions EXP isoquercitrin inhibits the reaction [EGF protein results in increased phosphorylation of MAPK3 protein] CTD PMID:26109002 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506 		JBrowse link
G MCL1 MCL1 apoptosis regulator, BCL2 family member affects expression EXP isoquercitrin affects the expression of MCL1 mRNA CTD PMID:30597948 NCBI chr 1:150,574,558...150,579,610
Ensembl chr 1:150,560,895...150,579,738 		JBrowse link
G ME1 malic enzyme 1 multiple interactions ISO isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with oxfendazole] results in increased expression of ME1 mRNA] CTD PMID:20033131 NCBI chr 6:83,210,402...83,431,051
Ensembl chr 6:83,210,402...83,431,051 		JBrowse link
G MMP2 matrix metallopeptidase 2 multiple interactions EXP isoquercitrin results in decreased expression of and results in decreased activity of MMP2 protein CTD PMID:18715546 NCBI chr16:55,478,830...55,506,691
Ensembl chr16:55,389,700...55,506,691 		JBrowse link
G MMP9 matrix metallopeptidase 9 multiple interactions EXP isoquercitrin results in decreased expression of and results in decreased activity of MMP9 protein CTD PMID:18715546 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561 		JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 multiple interactions ISO isoquercitrin inhibits the reaction [Streptozocin results in increased expression of NFE2L2 mRNA] CTD PMID:30817903 NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756 		JBrowse link
G NFKB1 nuclear factor kappa B subunit 1 multiple interactions ISO [isoquercitrin analog co-treated with Propylthiouracil] results in decreased expression of NFKB1 mRNA CTD PMID:31068541 NCBI chr 4:102,501,359...102,617,302
Ensembl chr 4:102,501,330...102,617,302 		JBrowse link
G NFKBIA NFKB inhibitor alpha multiple interactions ISO isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of NFKBIA mRNA] CTD PMID:20045035 NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749 		JBrowse link
G NOS2 nitric oxide synthase 2 multiple interactions ISO isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of NOS2 mRNA] CTD PMID:21295105 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529 		JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 multiple interactions ISO [Diethylnitrosamine co-treated with oxfendazole co-treated with isoquercitrin] results in increased expression of NQO1 mRNA; isoquercitrin analog inhibits the reaction [Propylthiouracil results in increased expression of NQO1 mRNA] CTD PMID:20033131 PMID:31068541 NCBI chr16:69,709,401...69,726,560
Ensembl chr16:69,706,996...69,726,668 		JBrowse link
G NR3C2 nuclear receptor subfamily 3 group C member 2 multiple interactions ISO [Diethylnitrosamine co-treated with Dietary Fats co-treated with Canrenoic Acid co-treated with isoquercitrin analog] results in increased expression of NR3C2 mRNA CTD PMID:30298849 NCBI chr 4:148,078,764...148,445,508
Ensembl chr 4:148,078,762...148,444,698 		JBrowse link
G NSF N-ethylmaleimide sensitive factor, vesicle fusing ATPase multiple interactions ISO isoquercitrin inhibits the reaction [Oxidopamine results in decreased expression of NSF mRNA] CTD PMID:25129099 NCBI chr17:46,590,669...46,757,464
Ensembl chr17:46,590,669...46,757,679 		JBrowse link
G NSG1 neuronal vesicle trafficking associated 1 multiple interactions ISO isoquercitrin inhibits the reaction [Oxidopamine results in decreased expression of NSG1 mRNA] CTD PMID:25129099 NCBI chr 4:4,386,532...4,419,058
Ensembl chr 4:4,348,140...4,419,058 		JBrowse link
G OPA1 OPA1 mitochondrial dynamin like GTPase multiple interactions ISO isoquercitrin inhibits the reaction [Oxidopamine results in decreased expression of OPA1 mRNA] CTD PMID:25129099 NCBI chr 3:193,593,208...193,697,811
Ensembl chr 3:193,593,144...193,697,811 		JBrowse link
G OTX2 orthodenticle homeobox 2 multiple interactions ISO isoquercitrin analog inhibits the reaction [Propylthiouracil results in increased expression of OTX2 mRNA] CTD PMID:31068541 NCBI chr14:56,799,905...56,810,479
Ensembl chr14:56,799,905...56,816,693 		JBrowse link
G PARK7 Parkinsonism associated deglycase multiple interactions ISO isoquercitrin inhibits the reaction [Oxidopamine results in increased expression of PARK7 mRNA] CTD PMID:25129099 NCBI chr 1:7,961,711...7,985,505
Ensembl chr 1:7,954,291...7,985,505 		JBrowse link
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha affects expression EXP isoquercitrin affects the expression of PIK3CA mRNA CTD PMID:30597948 NCBI chr 3:179,148,126...179,240,093
Ensembl chr 3:179,148,114...179,240,093 		JBrowse link
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 increases expression EXP isoquercitrin results in increased expression of PIK3R1 mRNA CTD PMID:30597948 NCBI chr 5:68,215,756...68,301,821
Ensembl chr 5:68,215,740...68,301,821 		JBrowse link
G PPID peptidylprolyl isomerase D multiple interactions ISO isoquercitrin inhibits the reaction [Oxidopamine results in increased expression of PPID mRNA] CTD PMID:25129099 NCBI chr 4:158,709,127...158,723,396
Ensembl chr 4:158,709,127...158,723,396 		JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase multiple interactions ISO isoquercitrin inhibits the reaction [Oxidopamine results in increased expression of PRKN mRNA] CTD PMID:25129099 NCBI chr 6:161,347,417...162,727,766
Ensembl chr 6:161,347,417...162,727,775 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PTGS2 mRNA]; isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PTGS2 protein]; isoquercitrin inhibits the reaction [Carrageenan results in increased expression of PTGS2 mRNA]; isoquercitrin inhibits the reaction [Streptozocin results in increased expression of PTGS2 mRNA] CTD PMID:14654164 PMID:20045035 PMID:30817903 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922 		JBrowse link
G PTK2 protein tyrosine kinase 2 multiple interactions EXP isoquercitrin inhibits the reaction [EGF protein results in increased phosphorylation of PTK2 protein] CTD PMID:26109002 NCBI chr 8:140,657,900...141,002,079
Ensembl chr 8:140,657,900...141,002,216 		JBrowse link
G RELB RELB proto-oncogene, NF-kB subunit increases expression EXP isoquercitrin results in increased expression of RELB mRNA CTD PMID:30597948 NCBI chr19:45,001,464...45,038,192
Ensembl chr19:45,001,461...45,038,192 		JBrowse link
G RUNX2 RUNX family transcription factor 2 increases expression ISO isoquercitrin results in increased expression of RUNX2 mRNA CTD PMID:30365939 NCBI chr 6:45,328,330...45,551,082
Ensembl chr 6:45,328,157...45,664,349 		JBrowse link
G SC5D sterol-C5-desaturase multiple interactions EXP [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of SC5D mRNA CTD PMID:18032389 NCBI chr11:121,292,771...121,313,410
Ensembl chr11:121,292,681...121,313,410 		JBrowse link
G SERPINE1 serpin family E member 1 multiple interactions ISO isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SERPINE1 mRNA] CTD PMID:20045035 NCBI chr 7:101,127,104...101,139,247
Ensembl chr 7:101,127,104...101,139,247 		JBrowse link
G SLC5A1 solute carrier family 5 member 1 multiple interactions EXP isoquercitrin inhibits the reaction [SLC5A1 protein results in increased uptake of methylglucoside] CTD PMID:17495124 NCBI chr22:32,043,261...32,113,029
Ensembl chr22:32,043,261...32,113,029 		JBrowse link
G SQLE squalene epoxidase multiple interactions EXP [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of SQLE mRNA CTD PMID:18032389 NCBI chr 8:124,998,505...125,022,283
Ensembl chr 8:124,998,497...125,022,283 		JBrowse link
G SREBF2 sterol regulatory element binding transcription factor 2 multiple interactions EXP [isoquercitrin co-treated with Hydrogen Peroxide] results in increased cleavage of and results in increased activity of SREBF2 protein; [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of SREBF2 mRNA; SREBF2 protein affects the susceptibility to [isoquercitrin co-treated with Hydrogen Peroxide] CTD PMID:18032389 NCBI chr22:41,833,105...41,907,305
Ensembl chr22:41,833,105...41,907,306 		JBrowse link
G STAT3 signal transducer and activator of transcription 3 increases expression EXP isoquercitrin results in increased expression of STAT3 mRNA CTD PMID:30597948 NCBI chr17:42,313,324...42,388,442
Ensembl chr17:42,313,324...42,388,568 		JBrowse link
G STAT6 signal transducer and activator of transcription 6 increases expression EXP isoquercitrin results in increased expression of STAT6 mRNA CTD PMID:30597948 NCBI chr12:57,095,408...57,111,362
Ensembl chr12:57,095,408...57,132,139 		JBrowse link
G STUB1 STIP1 homology and U-box containing protein 1 multiple interactions ISO isoquercitrin inhibits the reaction [Oxidopamine results in increased expression of STUB1 mRNA] CTD PMID:25129099 NCBI chr16:680,410...682,801
Ensembl chr16:680,224...682,870 		JBrowse link
G TH tyrosine hydroxylase multiple interactions ISO isoquercitrin promotes the reaction [Oxidopamine results in decreased expression of TH mRNA] CTD PMID:25129099 NCBI chr11:2,163,929...2,171,815
Ensembl chr11:2,163,929...2,171,815 		JBrowse link
G TIMP1 TIMP metallopeptidase inhibitor 1 increases expression EXP isoquercitrin results in increased expression of TIMP1 protein CTD PMID:18715546 NCBI chr  X:47,582,436...47,586,789
Ensembl chr  X:47,582,408...47,586,789 		JBrowse link
G TNF tumor necrosis factor multiple interactions ISO isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of TNF mRNA]; isoquercitrin inhibits the reaction [Carrageenan results in increased expression of TNF protein]; isoquercitrin inhibits the reaction [Streptozocin results in increased expression of TNF mRNA] CTD PMID:14654164 PMID:21295105 PMID:30817903 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TNFRSF1A TNF receptor superfamily member 1A multiple interactions ISO isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of TNFRSF1A protein] CTD PMID:21295105 NCBI chr12:6,328,771...6,342,076
Ensembl chr12:6,328,757...6,342,114 		JBrowse link
G TP53 tumor protein p53 multiple interactions ISO isoquercitrin inhibits the reaction [Streptozocin results in increased expression of TP53 mRNA] CTD PMID:30817903 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,546 		JBrowse link
G TRADD TNFRSF1A associated via death domain multiple interactions ISO isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of TRADD protein] CTD PMID:21295105 NCBI chr16:67,154,185...67,159,909
Ensembl chr16:67,154,185...67,159,909 		JBrowse link
G TXN thioredoxin multiple interactions ISO isoquercitrin analog inhibits the reaction [Propylthiouracil results in increased expression of TXN1 mRNA] CTD PMID:31068541 NCBI chr 9:110,243,810...110,256,507
Ensembl chr 9:110,243,810...110,256,507 		JBrowse link
G TYK2 tyrosine kinase 2 affects expression EXP isoquercitrin affects the expression of TYK2 mRNA CTD PMID:30597948 NCBI chr19:10,350,533...10,380,572
Ensembl chr19:10,350,533...10,380,608 		JBrowse link
G UCHL1 ubiquitin C-terminal hydrolase L1 multiple interactions ISO isoquercitrin inhibits the reaction [Oxidopamine results in increased expression of UCHL1 mRNA] CTD PMID:25129099 NCBI chr 4:41,256,928...41,268,455
Ensembl chr 4:41,256,413...41,268,455 		JBrowse link
quercetin 3-O-beta-D-glucopyranoside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACAT2 acetyl-CoA acetyltransferase 2 multiple interactions EXP [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of ACAT2 mRNA CTD PMID:18032389 NCBI chr 6:159,762,045...159,779,112
Ensembl chr 6:159,762,045...159,779,112 		JBrowse link
G AKR7A3 aldo-keto reductase family 7 member A3 multiple interactions ISO [Diethylnitrosamine co-treated with oxfendazole co-treated with isoquercitrin] results in increased expression of AKR7A3 mRNA CTD PMID:20033131 NCBI chr 1:19,274,229...19,288,770
Ensembl chr 1:19,282,573...19,288,770 		JBrowse link
G APOA1 apolipoprotein A1 increases secretion EXP isoquercitrin results in increased secretion of APOA1 protein CTD PMID:24963805 NCBI chr11:116,835,751...116,837,950
Ensembl chr11:116,835,751...116,837,622 		JBrowse link
G ATF6 activating transcription factor 6 increases expression ISO isoquercitrin results in increased expression of ATF6 mRNA CTD PMID:30365939 NCBI chr 1:161,766,320...161,964,070
Ensembl chr 1:161,766,298...161,977,574 		JBrowse link
G ATXN2 ataxin 2 multiple interactions ISO isoquercitrin inhibits the reaction [Oxidopamine results in increased expression of ATXN2 mRNA] CTD PMID:25129099 NCBI chr12:111,452,214...111,599,673
Ensembl chr12:111,443,485...111,599,676 		JBrowse link
G ATXN3 ataxin 3 multiple interactions ISO isoquercitrin inhibits the reaction [Oxidopamine results in increased expression of ATXN3 mRNA] CTD PMID:25129099 NCBI chr14:92,044,775...92,106,582
Ensembl chr14:92,044,496...92,106,621 		JBrowse link
G BCL2 BCL2 apoptosis regulator decreases expression EXP isoquercitrin results in decreased expression of BCL2 mRNA CTD PMID:30597948 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128 		JBrowse link
G CASP3 caspase 3 affects expression EXP isoquercitrin affects the expression of CASP3 mRNA CTD PMID:30597948 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062 		JBrowse link
G CASP8 caspase 8 decreases expression EXP isoquercitrin results in decreased expression of CASP8 mRNA CTD PMID:30597948 NCBI chr 2:201,233,463...201,287,711
Ensembl chr 2:201,233,443...201,361,836 		JBrowse link
G CAT catalase multiple interactions ISO [Diethylnitrosamine co-treated with Dietary Fats co-treated with Canrenoic Acid co-treated with isoquercitrin analog] results in increased expression of CAT mRNA; isoquercitrin inhibits the reaction [Streptozocin results in decreased activity of CAT protein] CTD PMID:30298849 PMID:30817903 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060 		JBrowse link
G CCL2 C-C motif chemokine ligand 2 multiple interactions ISO isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CCL2 mRNA] CTD PMID:21295105 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208 		JBrowse link
G CCL5 C-C motif chemokine ligand 5 multiple interactions ISO isoquercitrin inhibits the reaction [Carrageenan results in increased expression of CCL5 protein] CTD PMID:14654164 NCBI chr17:35,871,491...35,880,360
Ensembl chr17:35,871,491...35,880,793 		JBrowse link
G CDKN2B cyclin dependent kinase inhibitor 2B multiple interactions ISO isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CDKN2B mRNA] CTD PMID:21295105 NCBI chr 9:22,002,903...22,009,313
Ensembl chr 9:22,002,903...22,009,305 		JBrowse link
G CTNNB1 catenin beta 1 affects expression EXP isoquercitrin affects the expression of CTNNB1 mRNA CTD PMID:30597948 NCBI chr 3:41,199,505...41,240,443
Ensembl chr 3:41,194,741...41,260,096 		JBrowse link
G CXCL2 C-X-C motif chemokine ligand 2 multiple interactions ISO isoquercitrin inhibits the reaction [Carrageenan results in increased expression of CXCL2 protein] CTD PMID:14654164 NCBI chr 4:74,097,040...74,099,195
Ensembl chr 4:74,097,040...74,099,196 		JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 increases expression EXP isoquercitrin results in increased expression of CXCL8 mRNA CTD PMID:30597948 NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716 		JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 decreases activity
multiple interactions		 EXP
ISO		 isoquercitrin results in decreased activity of CYP1A1 protein
[Diethylnitrosamine co-treated with oxfendazole co-treated with isoquercitrin] results in increased expression of CYP1A1 mRNA		 CTD PMID:16271822 PMID:20033131 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536 		JBrowse link
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 multiple interactions ISO [Diethylnitrosamine co-treated with oxfendazole co-treated with isoquercitrin] results in increased expression of CYP1A2 mRNA CTD PMID:20033131 NCBI chr15:74,748,845...74,756,607
Ensembl chr15:74,748,845...74,756,607 		JBrowse link
G CYP1B1 cytochrome P450 family 1 subfamily B member 1 decreases activity EXP isoquercitrin results in decreased activity of CYP1B1 protein CTD PMID:16271822 NCBI chr 2:38,067,509...38,076,151
Ensembl chr 2:38,066,973...38,109,902 		JBrowse link
G CYP51A1 cytochrome P450 family 51 subfamily A member 1 multiple interactions EXP [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of CYP51A1 mRNA CTD PMID:18032389 NCBI chr 7:92,112,153...92,134,803
Ensembl chr 7:92,084,987...92,134,803 		JBrowse link
G DHCR7 7-dehydrocholesterol reductase multiple interactions EXP [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of DHCR7 mRNA CTD PMID:18032389 NCBI chr11:71,434,411...71,448,393
Ensembl chr11:71,428,193...71,452,868 		JBrowse link
G EGF epidermal growth factor multiple interactions EXP isoquercitrin inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein]; isoquercitrin inhibits the reaction [EGF protein results in increased phosphorylation of MAPK1 protein]; isoquercitrin inhibits the reaction [EGF protein results in increased phosphorylation of MAPK3 protein]; isoquercitrin inhibits the reaction [EGF protein results in increased phosphorylation of PTK2 protein] CTD PMID:26109002 NCBI chr 4:109,912,883...110,013,766
Ensembl chr 4:109,912,883...110,013,766 		JBrowse link
G EGFR epidermal growth factor receptor multiple interactions EXP isoquercitrin inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein] CTD PMID:26109002 NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628 		JBrowse link
G EGLN1 egl-9 family hypoxia inducible factor 1 multiple interactions ISO isoquercitrin inhibits the reaction [Oxidopamine results in increased expression of EGLN1 mRNA] CTD PMID:25129099 NCBI chr 1:231,363,756...231,422,287
Ensembl chr 1:231,363,751...231,422,287 		JBrowse link
G FDFT1 farnesyl-diphosphate farnesyltransferase 1 multiple interactions EXP [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of FDFT1 mRNA CTD PMID:18032389 NCBI chr 8:11,795,582...11,839,309
Ensembl chr 8:11,795,573...11,839,395 		JBrowse link
G FDPS farnesyl diphosphate synthase multiple interactions EXP [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of FDPS mRNA CTD PMID:18032389 NCBI chr 1:155,308,866...155,320,665
Ensembl chr 1:155,308,748...155,320,666 		JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO [isoquercitrin analog co-treated with Propylthiouracil] results in decreased expression of FOS mRNA CTD PMID:31068541 NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,282,230 		JBrowse link
G GPX2 glutathione peroxidase 2 multiple interactions ISO [Diethylnitrosamine co-treated with oxfendazole co-treated with isoquercitrin] results in increased expression of GPX2 mRNA CTD PMID:20033131 NCBI chr14:64,939,158...64,942,745
Ensembl chr14:64,939,152...64,942,746 		JBrowse link
G GRIA3 glutamate ionotropic receptor AMPA type subunit 3 multiple interactions ISO isoquercitrin analog inhibits the reaction [Propylthiouracil results in increased expression of GRIA3 mRNA] CTD PMID:31068541 NCBI chr  X:123,184,278...123,490,915
Ensembl chr  X:123,184,153...123,490,915 		JBrowse link
G GSTA5 glutathione S-transferase alpha 5 multiple interactions ISO [isoquercitrin co-treated with oxfendazole co-treated with Diethylnitrosamine] results in increased expression of GSTA5 mRNA; isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of GSTA5 mRNA] CTD PMID:20033131 PMID:20045035 NCBI chr 6:52,831,692...52,846,245
Ensembl chr 6:52,831,655...52,840,843 		JBrowse link
G GSTM1 glutathione S-transferase mu 1 multiple interactions ISO [Diethylnitrosamine co-treated with oxfendazole co-treated with isoquercitrin] results in increased expression of GSTM1 mRNA; isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of GSTM1 mRNA] CTD PMID:20033131 PMID:20045035 NCBI chr 1:109,687,817...109,693,745
Ensembl chr 1:109,687,814...109,709,039 		JBrowse link
G HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase multiple interactions EXP [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of HMGCR mRNA CTD PMID:18032389 NCBI chr 5:75,336,529...75,362,116
Ensembl chr 5:75,336,329...75,364,001 		JBrowse link
G HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 multiple interactions EXP [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of HMGCS1 mRNA CTD PMID:18032389 NCBI chr 5:43,287,470...43,313,412
Ensembl chr 5:43,287,470...43,313,512 		JBrowse link
G HMOX1 heme oxygenase 1 multiple interactions ISO isoquercitrin inhibits the reaction [beta-Naphthoflavone results in increased expression of HMOX1 protein]; isoquercitrin inhibits the reaction [Streptozocin results in increased expression of HMOX1 mRNA] CTD PMID:21295105 PMID:30817903 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214 		JBrowse link
G IBSP integrin binding sialoprotein increases expression ISO isoquercitrin results in increased expression of IBSP mRNA CTD PMID:30365939 NCBI chr 4:87,799,554...87,812,435
Ensembl chr 4:87,799,554...87,812,435 		JBrowse link
G IL1A interleukin 1 alpha multiple interactions ISO [isoquercitrin analog co-treated with Propylthiouracil] results in increased expression of IL1A mRNA; [isoquercitrin co-treated with Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of IL1A mRNA CTD PMID:21295105 PMID:31068541 NCBI chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493 		JBrowse link
G IL1B interleukin 1 beta multiple interactions ISO isoquercitrin inhibits the reaction [Streptozocin results in increased expression of IL1B mRNA] CTD PMID:30817903 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL6 interleukin 6 multiple interactions ISO isoquercitrin inhibits the reaction [Streptozocin results in increased expression of IL6 mRNA] CTD PMID:30817903 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G INS-IGF2 INS-IGF2 readthrough multiple interactions ISO isoquercitrin inhibits the reaction [Streptozocin results in increased expression of INS1 protein] CTD PMID:30817903 NCBI chr11:2,129,117...2,161,209
Ensembl chr11:2,132,538...2,161,209 		JBrowse link
G INSIG1 insulin induced gene 1 multiple interactions EXP [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of INSIG1 mRNA CTD PMID:18032389 NCBI chr 7:155,297,878...155,310,235
Ensembl chr 7:155,297,776...155,310,235 		JBrowse link
G JAK1 Janus kinase 1 increases expression EXP isoquercitrin results in increased expression of JAK1 mRNA CTD PMID:30597948 NCBI chr 1:64,833,229...65,067,746
Ensembl chr 1:64,833,223...65,067,754 		JBrowse link
G JAK2 Janus kinase 2 increases expression EXP isoquercitrin results in increased expression of JAK2 mRNA CTD PMID:30597948 NCBI chr 9:4,984,390...5,129,948
Ensembl chr 9:4,984,390...5,129,948 		JBrowse link
G KEAP1 kelch like ECH associated protein 1 multiple interactions ISO isoquercitrin inhibits the reaction [Streptozocin results in decreased expression of KEAP1 mRNA] CTD PMID:30817903 NCBI chr19:10,486,125...10,503,356
Ensembl chr19:10,486,125...10,503,558 		JBrowse link
G LCT lactase multiple interactions ISO [migalastat results in decreased activity of LCT protein] which results in decreased hydrolysis of isoquercitrin CTD PMID:12663055 NCBI chr 2:135,787,850...135,837,184
Ensembl chr 2:135,787,850...135,837,184 		JBrowse link
G LDLR low density lipoprotein receptor multiple interactions EXP [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of LDLR mRNA CTD PMID:18032389 NCBI chr19:11,089,463...11,133,820
Ensembl chr19:11,089,418...11,133,820 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 multiple interactions EXP isoquercitrin inhibits the reaction [EGF protein results in increased phosphorylation of MAPK1 protein] CTD PMID:26109002 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 multiple interactions EXP isoquercitrin inhibits the reaction [EGF protein results in increased phosphorylation of MAPK3 protein] CTD PMID:26109002 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506 		JBrowse link
G MCL1 MCL1 apoptosis regulator, BCL2 family member affects expression EXP isoquercitrin affects the expression of MCL1 mRNA CTD PMID:30597948 NCBI chr 1:150,574,558...150,579,610
Ensembl chr 1:150,560,895...150,579,738 		JBrowse link
G ME1 malic enzyme 1 multiple interactions ISO isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with oxfendazole] results in increased expression of ME1 mRNA] CTD PMID:20033131 NCBI chr 6:83,210,402...83,431,051
Ensembl chr 6:83,210,402...83,431,051 		JBrowse link
G MMP2 matrix metallopeptidase 2 multiple interactions EXP isoquercitrin results in decreased expression of and results in decreased activity of MMP2 protein CTD PMID:18715546 NCBI chr16:55,478,830...55,506,691
Ensembl chr16:55,389,700...55,506,691 		JBrowse link
G MMP9 matrix metallopeptidase 9 multiple interactions EXP isoquercitrin results in decreased expression of and results in decreased activity of MMP9 protein CTD PMID:18715546 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561 		JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 multiple interactions ISO isoquercitrin inhibits the reaction [Streptozocin results in increased expression of NFE2L2 mRNA] CTD PMID:30817903 NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756 		JBrowse link
G NFKB1 nuclear factor kappa B subunit 1 multiple interactions ISO [isoquercitrin analog co-treated with Propylthiouracil] results in decreased expression of NFKB1 mRNA CTD PMID:31068541 NCBI chr 4:102,501,359...102,617,302
Ensembl chr 4:102,501,330...102,617,302 		JBrowse link
G NFKBIA NFKB inhibitor alpha multiple interactions ISO isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of NFKBIA mRNA] CTD PMID:20045035 NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749 		JBrowse link
G NOS2 nitric oxide synthase 2 multiple interactions ISO isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of NOS2 mRNA] CTD PMID:21295105 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529 		JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 multiple interactions ISO [Diethylnitrosamine co-treated with oxfendazole co-treated with isoquercitrin] results in increased expression of NQO1 mRNA; isoquercitrin analog inhibits the reaction [Propylthiouracil results in increased expression of NQO1 mRNA] CTD PMID:20033131 PMID:31068541 NCBI chr16:69,709,401...69,726,560
Ensembl chr16:69,706,996...69,726,668 		JBrowse link
G NR3C2 nuclear receptor subfamily 3 group C member 2 multiple interactions ISO [Diethylnitrosamine co-treated with Dietary Fats co-treated with Canrenoic Acid co-treated with isoquercitrin analog] results in increased expression of NR3C2 mRNA CTD PMID:30298849 NCBI chr 4:148,078,764...148,445,508
Ensembl chr 4:148,078,762...148,444,698 		JBrowse link
G NSF N-ethylmaleimide sensitive factor, vesicle fusing ATPase multiple interactions ISO isoquercitrin inhibits the reaction [Oxidopamine results in decreased expression of NSF mRNA] CTD PMID:25129099 NCBI chr17:46,590,669...46,757,464
Ensembl chr17:46,590,669...46,757,679 		JBrowse link
G NSG1 neuronal vesicle trafficking associated 1 multiple interactions ISO isoquercitrin inhibits the reaction [Oxidopamine results in decreased expression of NSG1 mRNA] CTD PMID:25129099 NCBI chr 4:4,386,532...4,419,058
Ensembl chr 4:4,348,140...4,419,058 		JBrowse link
G OPA1 OPA1 mitochondrial dynamin like GTPase multiple interactions ISO isoquercitrin inhibits the reaction [Oxidopamine results in decreased expression of OPA1 mRNA] CTD PMID:25129099 NCBI chr 3:193,593,208...193,697,811
Ensembl chr 3:193,593,144...193,697,811 		JBrowse link
G OTX2 orthodenticle homeobox 2 multiple interactions ISO isoquercitrin analog inhibits the reaction [Propylthiouracil results in increased expression of OTX2 mRNA] CTD PMID:31068541 NCBI chr14:56,799,905...56,810,479
Ensembl chr14:56,799,905...56,816,693 		JBrowse link
G PARK7 Parkinsonism associated deglycase multiple interactions ISO isoquercitrin inhibits the reaction [Oxidopamine results in increased expression of PARK7 mRNA] CTD PMID:25129099 NCBI chr 1:7,961,711...7,985,505
Ensembl chr 1:7,954,291...7,985,505 		JBrowse link
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha affects expression EXP isoquercitrin affects the expression of PIK3CA mRNA CTD PMID:30597948 NCBI chr 3:179,148,126...179,240,093
Ensembl chr 3:179,148,114...179,240,093 		JBrowse link
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 increases expression EXP isoquercitrin results in increased expression of PIK3R1 mRNA CTD PMID:30597948 NCBI chr 5:68,215,756...68,301,821
Ensembl chr 5:68,215,740...68,301,821 		JBrowse link
G PPID peptidylprolyl isomerase D multiple interactions ISO isoquercitrin inhibits the reaction [Oxidopamine results in increased expression of PPID mRNA] CTD PMID:25129099 NCBI chr 4:158,709,127...158,723,396
Ensembl chr 4:158,709,127...158,723,396 		JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase multiple interactions ISO isoquercitrin inhibits the reaction [Oxidopamine results in increased expression of PRKN mRNA] CTD PMID:25129099 NCBI chr 6:161,347,417...162,727,766
Ensembl chr 6:161,347,417...162,727,775 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PTGS2 mRNA]; isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PTGS2 protein]; isoquercitrin inhibits the reaction [Carrageenan results in increased expression of PTGS2 mRNA]; isoquercitrin inhibits the reaction [Streptozocin results in increased expression of PTGS2 mRNA] CTD PMID:14654164 PMID:20045035 PMID:30817903 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922 		JBrowse link
G PTK2 protein tyrosine kinase 2 multiple interactions EXP isoquercitrin inhibits the reaction [EGF protein results in increased phosphorylation of PTK2 protein] CTD PMID:26109002 NCBI chr 8:140,657,900...141,002,079
Ensembl chr 8:140,657,900...141,002,216 		JBrowse link
G RELB RELB proto-oncogene, NF-kB subunit increases expression EXP isoquercitrin results in increased expression of RELB mRNA CTD PMID:30597948 NCBI chr19:45,001,464...45,038,192
Ensembl chr19:45,001,461...45,038,192 		JBrowse link
G RUNX2 RUNX family transcription factor 2 increases expression ISO isoquercitrin results in increased expression of RUNX2 mRNA CTD PMID:30365939 NCBI chr 6:45,328,330...45,551,082
Ensembl chr 6:45,328,157...45,664,349 		JBrowse link
G SC5D sterol-C5-desaturase multiple interactions EXP [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of SC5D mRNA CTD PMID:18032389 NCBI chr11:121,292,771...121,313,410
Ensembl chr11:121,292,681...121,313,410 		JBrowse link
G SERPINE1 serpin family E member 1 multiple interactions ISO isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SERPINE1 mRNA] CTD PMID:20045035 NCBI chr 7:101,127,104...101,139,247
Ensembl chr 7:101,127,104...101,139,247 		JBrowse link
G SLC5A1 solute carrier family 5 member 1 multiple interactions EXP isoquercitrin inhibits the reaction [SLC5A1 protein results in increased uptake of methylglucoside] CTD PMID:17495124 NCBI chr22:32,043,261...32,113,029
Ensembl chr22:32,043,261...32,113,029 		JBrowse link
G SQLE squalene epoxidase multiple interactions EXP [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of SQLE mRNA CTD PMID:18032389 NCBI chr 8:124,998,505...125,022,283
Ensembl chr 8:124,998,497...125,022,283 		JBrowse link
G SREBF2 sterol regulatory element binding transcription factor 2 multiple interactions EXP [isoquercitrin co-treated with Hydrogen Peroxide] results in increased cleavage of and results in increased activity of SREBF2 protein; [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of SREBF2 mRNA; SREBF2 protein affects the susceptibility to [isoquercitrin co-treated with Hydrogen Peroxide] CTD PMID:18032389 NCBI chr22:41,833,105...41,907,305
Ensembl chr22:41,833,105...41,907,306 		JBrowse link
G STAT3 signal transducer and activator of transcription 3 increases expression EXP isoquercitrin results in increased expression of STAT3 mRNA CTD PMID:30597948 NCBI chr17:42,313,324...42,388,442
Ensembl chr17:42,313,324...42,388,568 		JBrowse link
G STAT6 signal transducer and activator of transcription 6 increases expression EXP isoquercitrin results in increased expression of STAT6 mRNA CTD PMID:30597948 NCBI chr12:57,095,408...57,111,362
Ensembl chr12:57,095,408...57,132,139 		JBrowse link
G STUB1 STIP1 homology and U-box containing protein 1 multiple interactions ISO isoquercitrin inhibits the reaction [Oxidopamine results in increased expression of STUB1 mRNA] CTD PMID:25129099 NCBI chr16:680,410...682,801
Ensembl chr16:680,224...682,870 		JBrowse link
G TH tyrosine hydroxylase multiple interactions ISO isoquercitrin promotes the reaction [Oxidopamine results in decreased expression of TH mRNA] CTD PMID:25129099 NCBI chr11:2,163,929...2,171,815
Ensembl chr11:2,163,929...2,171,815 		JBrowse link
G TIMP1 TIMP metallopeptidase inhibitor 1 increases expression EXP isoquercitrin results in increased expression of TIMP1 protein CTD PMID:18715546 NCBI chr  X:47,582,436...47,586,789
Ensembl chr  X:47,582,408...47,586,789 		JBrowse link
G TNF tumor necrosis factor multiple interactions ISO isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of TNF mRNA]; isoquercitrin inhibits the reaction [Carrageenan results in increased expression of TNF protein]; isoquercitrin inhibits the reaction [Streptozocin results in increased expression of TNF mRNA] CTD PMID:14654164 PMID:21295105 PMID:30817903 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TNFRSF1A TNF receptor superfamily member 1A multiple interactions ISO isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of TNFRSF1A protein] CTD PMID:21295105 NCBI chr12:6,328,771...6,342,076
Ensembl chr12:6,328,757...6,342,114 		JBrowse link
G TP53 tumor protein p53 multiple interactions ISO isoquercitrin inhibits the reaction [Streptozocin results in increased expression of TP53 mRNA] CTD PMID:30817903 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,546 		JBrowse link
G TRADD TNFRSF1A associated via death domain multiple interactions ISO isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of TRADD protein] CTD PMID:21295105 NCBI chr16:67,154,185...67,159,909
Ensembl chr16:67,154,185...67,159,909 		JBrowse link
G TXN thioredoxin multiple interactions ISO isoquercitrin analog inhibits the reaction [Propylthiouracil results in increased expression of TXN1 mRNA] CTD PMID:31068541 NCBI chr 9:110,243,810...110,256,507
Ensembl chr 9:110,243,810...110,256,507 		JBrowse link
G TYK2 tyrosine kinase 2 affects expression EXP isoquercitrin affects the expression of TYK2 mRNA CTD PMID:30597948 NCBI chr19:10,350,533...10,380,572
Ensembl chr19:10,350,533...10,380,608 		JBrowse link
G UCHL1 ubiquitin C-terminal hydrolase L1 multiple interactions ISO isoquercitrin inhibits the reaction [Oxidopamine results in increased expression of UCHL1 mRNA] CTD PMID:25129099 NCBI chr 4:41,256,928...41,268,455
Ensembl chr 4:41,256,413...41,268,455 		JBrowse link
quercetin 4'-O-beta-D-glucopyranoside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKT1 AKT serine/threonine kinase 1 multiple interactions EXP 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [spiraeoside inhibits the reaction [Glucose results in decreased phosphorylation of AKT1 protein]]; spiraeoside inhibits the reaction [Glucose results in decreased phosphorylation of AKT1 protein] CTD PMID:32602595 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,759 		JBrowse link
G AP5M1 adaptor related protein complex 5 subunit mu 1 decreases expression EXP spiraeoside results in decreased expression of AP5M1 protein CTD PMID:34116102 NCBI chr14:57,268,971...57,298,742
Ensembl chr14:57,268,924...57,298,742 		JBrowse link
G BAX BCL2 associated X, apoptosis regulator multiple interactions EXP 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [spiraeoside inhibits the reaction [Glucose results in increased expression of BAX protein]]; spiraeoside inhibits the reaction [Glucose results in increased expression of BAX protein] CTD PMID:32602595 NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798 		JBrowse link
G BCL2 BCL2 apoptosis regulator multiple interactions
decreases expression		 EXP 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [spiraeoside inhibits the reaction [Glucose results in decreased expression of BCL2 protein]]; spiraeoside inhibits the reaction [Glucose results in decreased expression of BCL2 protein]
spiraeoside results in decreased expression of BCL2 protein		 CTD PMID:32602595 PMID:34116102 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128 		JBrowse link
G BID BH3 interacting domain death agonist decreases expression EXP spiraeoside results in decreased expression of BID protein CTD PMID:34116102 NCBI chr22:17,734,138...17,774,665
Ensembl chr22:17,734,138...17,774,770 		JBrowse link
G CASP3 caspase 3 decreases expression EXP spiraeoside results in decreased expression of CASP3 protein CTD PMID:34116102 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062 		JBrowse link
G CASP9 caspase 9 decreases expression EXP spiraeoside results in decreased expression of CASP9 protein CTD PMID:34116102 NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534 		JBrowse link
G CAT catalase multiple interactions EXP 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [spiraeoside inhibits the reaction [Glucose results in increased activity of CAT protein]]; spiraeoside inhibits the reaction [Glucose results in increased activity of CAT protein] CTD PMID:32602595 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060 		JBrowse link
G CDK2 cyclin dependent kinase 2 decreases expression EXP spiraeoside results in decreased expression of CDK2 protein CTD PMID:34116102 NCBI chr12:55,966,830...55,972,789
Ensembl chr12:55,966,781...55,972,789 		JBrowse link
G CRYZ crystallin zeta increases activity ISO spiraeoside results in increased activity of CRYZ protein CTD PMID:8968052 NCBI chr 1:74,705,486...74,733,050
Ensembl chr 1:74,705,482...74,733,408 		JBrowse link
G HMOX1 heme oxygenase 1 multiple interactions EXP 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [spiraeoside inhibits the reaction [Glucose results in decreased expression of HMOX1 protein]]; spiraeoside inhibits the reaction [Glucose results in decreased expression of HMOX1 protein] CTD PMID:32602595 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214 		JBrowse link
G LCT lactase multiple interactions ISO [migalastat results in decreased activity of LCT protein] which results in decreased hydrolysis of spiraeoside CTD PMID:12663055 NCBI chr 2:135,787,850...135,837,184
Ensembl chr 2:135,787,850...135,837,184 		JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 multiple interactions EXP 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [spiraeoside inhibits the reaction [Glucose results in decreased expression of NFE2L2 protein]]; spiraeoside inhibits the reaction [Glucose results in decreased expression of NFE2L2 protein] CTD PMID:32602595 NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756 		JBrowse link
G PLCG2 phospholipase C gamma 2 decreases phosphorylation EXP spiraeoside results in decreased phosphorylation of PLCG2 protein CTD PMID:15613018 NCBI chr16:81,779,291...81,962,685
Ensembl chr16:81,779,279...81,962,685 		JBrowse link
G SLC5A1 solute carrier family 5 member 1 multiple interactions ISO
EXP		 [Phlorhizin results in decreased activity of SLC5A1 protein] which results in decreased uptake of spiraeoside
spiraeoside inhibits the reaction [SLC5A1 protein results in increased uptake of methylglucoside]		 CTD PMID:12663055 PMID:17495124 NCBI chr22:32,043,261...32,113,029
Ensembl chr22:32,043,261...32,113,029 		JBrowse link
G SYK spleen associated tyrosine kinase decreases phosphorylation EXP spiraeoside results in decreased phosphorylation of SYK protein CTD PMID:15613018 NCBI chr 9:90,801,600...90,898,549
Ensembl chr 9:90,801,787...90,898,549 		JBrowse link
rebaudioside A term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACE angiotensin I converting enzyme decreases expression EXP rebaudioside A results in decreased expression of ACE mRNA CTD PMID:31655124 NCBI chr17:63,477,061...63,498,373
Ensembl chr17:63,477,061...63,498,380 		JBrowse link
G ACOX1 acyl-CoA oxidase 1 multiple interactions ISO rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of ACOX1 mRNA] CTD PMID:25554529 NCBI chr17:75,941,507...75,979,166
Ensembl chr17:75,941,507...75,979,177 		JBrowse link
G ACTA2 actin alpha 2, smooth muscle multiple interactions ISO rebaudioside A inhibits the reaction [Thioacetamide results in increased expression of ACTA2 protein] CTD PMID:30883860 NCBI chr10:88,935,074...88,991,337
Ensembl chr10:88,934,822...88,991,339 		JBrowse link
G AGTR1 angiotensin II receptor type 1 increases expression EXP rebaudioside A results in increased expression of AGTR1 mRNA CTD PMID:31655124 NCBI chr 3:148,697,903...148,743,003
Ensembl chr 3:148,697,784...148,743,008 		JBrowse link
G ALOX5 arachidonate 5-lipoxygenase increases expression EXP rebaudioside A results in increased expression of ALOX5 mRNA CTD PMID:31655124 NCBI chr10:45,374,216...45,446,117
Ensembl chr10:45,374,176...45,446,119 		JBrowse link
G BAX BCL2 associated X, apoptosis regulator decreases expression EXP rebaudioside A results in decreased expression of BAX mRNA CTD PMID:31655124 NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798 		JBrowse link
G CALCA calcitonin related polypeptide alpha increases expression EXP rebaudioside A results in increased expression of CALCA mRNA CTD PMID:31655124 NCBI chr11:14,966,668...14,972,351
Ensembl chr11:14,966,622...14,972,354 		JBrowse link
G CAT catalase multiple interactions ISO rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of CAT mRNA] CTD PMID:25554529 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060 		JBrowse link
G CAV1 caveolin 1 decreases expression EXP rebaudioside A results in decreased expression of CAV1 mRNA CTD PMID:31655124 NCBI chr 7:116,525,009...116,561,185
Ensembl chr 7:116,524,994...116,561,179 		JBrowse link
G CCL2 C-C motif chemokine ligand 2 decreases expression EXP rebaudioside A results in decreased expression of CCL2 mRNA CTD PMID:31655124 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208 		JBrowse link
G CFLAR CASP8 and FADD like apoptosis regulator decreases expression EXP rebaudioside A results in decreased expression of CFLAR mRNA CTD PMID:31655124 NCBI chr 2:201,116,164...201,176,687
Ensembl chr 2:201,116,154...201,176,687 		JBrowse link
G CPT1A carnitine palmitoyltransferase 1A multiple interactions ISO rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of CPT1A mRNA] CTD PMID:25554529 NCBI chr11:68,754,620...68,844,277
Ensembl chr11:68,754,620...68,844,410 		JBrowse link
G DGAT2 diacylglycerol O-acyltransferase 2 multiple interactions ISO rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of DGAT2 mRNA] CTD PMID:25554529 NCBI chr11:75,768,778...75,801,534
Ensembl chr11:75,759,512...75,801,535 		JBrowse link
G EDN1 endothelin 1 decreases expression EXP rebaudioside A results in decreased expression of EDN1 mRNA CTD PMID:31655124 NCBI chr 6:12,230,516...12,297,194
Ensembl chr 6:12,290,361...12,297,194 		JBrowse link
G EDNRA endothelin receptor type A increases expression EXP rebaudioside A results in increased expression of EDNRA mRNA CTD PMID:31655124 NCBI chr 4:147,481,097...147,544,954
Ensembl chr 4:147,480,917...147,544,954 		JBrowse link
G F2R coagulation factor II thrombin receptor decreases expression EXP rebaudioside A results in decreased expression of F2R mRNA CTD PMID:31655124 NCBI chr 5:76,716,126...76,735,770
Ensembl chr 5:76,716,126...76,735,770 		JBrowse link
G FASLG Fas ligand increases expression EXP rebaudioside A results in increased expression of FASLG mRNA CTD PMID:31655124 NCBI chr 1:172,659,103...172,666,876
Ensembl chr 1:172,659,103...172,666,876 		JBrowse link
G FGF1 fibroblast growth factor 1 increases expression EXP rebaudioside A results in increased expression of FGF1 mRNA CTD PMID:31655124 NCBI chr 5:142,592,178...142,698,070
Ensembl chr 5:142,592,178...142,698,070 		JBrowse link
G FLT1 fms related receptor tyrosine kinase 1 decreases expression EXP rebaudioside A results in decreased expression of FLT1 mRNA CTD PMID:31655124 NCBI chr13:28,300,346...28,495,128
Ensembl chr13:28,300,346...28,495,145 		JBrowse link
G FOXO1 forkhead box O1 multiple interactions ISO rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of FOXO1 mRNA] CTD PMID:25554529 NCBI chr13:40,555,667...40,666,641
Ensembl chr13:40,555,667...40,666,641 		JBrowse link
G G6PC1 glucose-6-phosphatase catalytic subunit 1 multiple interactions ISO rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of G6PC1 mRNA] CTD PMID:25554529 NCBI chr17:42,900,799...42,914,438
Ensembl chr17:42,900,797...42,914,438 		JBrowse link
G IL10 interleukin 10 multiple interactions ISO rebaudioside A inhibits the reaction [Thioacetamide results in increased expression of IL10 protein] CTD PMID:30883860 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541 		JBrowse link
G IL6 interleukin 6 multiple interactions ISO rebaudioside A inhibits the reaction [Thioacetamide results in increased expression of IL6 protein] CTD PMID:30883860 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G INSR insulin receptor multiple interactions ISO rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of INSR mRNA] CTD PMID:25554529 NCBI chr19:7,112,265...7,294,414
Ensembl chr19:7,112,255...7,294,414 		JBrowse link
G IRS1 insulin receptor substrate 1 multiple interactions ISO rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of IRS1 mRNA] CTD PMID:25554529 NCBI chr 2:226,731,312...226,799,820
Ensembl chr 2:226,731,312...226,799,820 		JBrowse link
G IRS2 insulin receptor substrate 2 multiple interactions ISO rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of IRS2 mRNA] CTD PMID:25554529 NCBI chr13:109,752,695...109,786,583
Ensembl chr13:109,752,695...109,786,583 		JBrowse link
G ITGAV integrin subunit alpha V decreases expression EXP rebaudioside A results in decreased expression of ITGAV mRNA CTD PMID:31655124 NCBI chr 2:186,590,056...186,680,901
Ensembl chr 2:186,590,010...186,680,901 		JBrowse link
G KIT KIT proto-oncogene, receptor tyrosine kinase decreases expression EXP rebaudioside A results in decreased expression of KIT mRNA CTD PMID:31655124 NCBI chr 4:54,657,957...54,740,715
Ensembl chr 4:54,657,267...54,740,783 		JBrowse link
G LDLR low density lipoprotein receptor multiple interactions ISO rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of ACOX1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of CAT mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of CPT1A mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of DGAT2 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of FOXO1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of G6PC1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of INSR mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of IRS1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of IRS2 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of LIPC mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of MTOR mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of NFKB1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of NFKBIA mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PCK1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARA mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARD mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARG mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARGC1A mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SCD1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SIRT1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SLC27A1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SLC2A2 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SOD2 mRNA] CTD PMID:25554529 NCBI chr19:11,089,463...11,133,820
Ensembl chr19:11,089,418...11,133,820 		JBrowse link
G LEP leptin multiple interactions ISO rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of ACOX1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of CAT mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of CPT1A mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of DGAT2 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of FOXO1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of G6PC1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of INSR mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of IRS1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of IRS2 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of LIPC mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of MTOR mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of NFKB1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of NFKBIA mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PCK1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARA mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARD mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARG mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARGC1A mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SCD1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SIRT1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SLC27A1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SLC2A2 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SOD2 mRNA] CTD PMID:25554529 NCBI chr 7:128,241,278...128,257,629
Ensembl chr 7:128,241,278...128,257,629 		JBrowse link
G LIPC lipase C, hepatic type multiple interactions ISO rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of LIPC mRNA] CTD PMID:25554529 NCBI chr15:58,431,991...58,569,844
Ensembl chr15:58,410,569...58,569,844 		JBrowse link
G MMP13 matrix metallopeptidase 13 multiple interactions ISO rebaudioside A inhibits the reaction [Thioacetamide results in increased expression of MMP13 protein] CTD PMID:30883860 NCBI chr11:102,942,995...102,955,732
Ensembl chr11:102,942,995...102,955,732 		JBrowse link
G MMP2 matrix metallopeptidase 2 multiple interactions ISO rebaudioside A inhibits the reaction [Thioacetamide results in increased activity of MMP2 protein] CTD PMID:30883860 NCBI chr16:55,478,830...55,506,691
Ensembl chr16:55,389,700...55,506,691 		JBrowse link
G MMP9 matrix metallopeptidase 9 increases expression
multiple interactions		 EXP
ISO		 rebaudioside A results in increased expression of MMP9 mRNA
rebaudioside A inhibits the reaction [Thioacetamide results in increased activity of MMP9 protein]		 CTD PMID:30883860 PMID:31655124 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561 		JBrowse link
G MTOR mechanistic target of rapamycin kinase multiple interactions ISO rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of MTOR mRNA] CTD PMID:25554529 NCBI chr 1:11,106,535...11,262,551
Ensembl chr 1:11,106,535...11,262,556 		JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 multiple interactions ISO rebaudioside A inhibits the reaction [Thioacetamide results in decreased expression of NFE2L2 protein] CTD PMID:30883860 NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756 		JBrowse link
G NFKB1 nuclear factor kappa B subunit 1 multiple interactions ISO rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of NFKB1 mRNA] CTD PMID:25554529 NCBI chr 4:102,501,359...102,617,302
Ensembl chr 4:102,501,330...102,617,302 		JBrowse link
G NFKBIA NFKB inhibitor alpha multiple interactions ISO rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of NFKBIA mRNA] CTD PMID:25554529 NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749 		JBrowse link
G PCK1 phosphoenolpyruvate carboxykinase 1 multiple interactions ISO rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PCK1 mRNA] CTD PMID:25554529 NCBI chr20:57,561,110...57,568,121
Ensembl chr20:57,561,080...57,568,121 		JBrowse link
G PF4 platelet factor 4 increases expression EXP rebaudioside A results in increased expression of PF4 mRNA CTD PMID:31655124 NCBI chr 4:73,980,811...73,982,124
Ensembl chr 4:73,980,811...73,982,027 		JBrowse link
G PPARA peroxisome proliferator activated receptor alpha multiple interactions ISO rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARA mRNA] CTD PMID:25554529 NCBI chr22:46,150,526...46,243,756
Ensembl chr22:46,150,521...46,243,755 		JBrowse link
G PPARD peroxisome proliferator activated receptor delta multiple interactions ISO rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARD mRNA] CTD PMID:25554529 NCBI chr 6:35,342,558...35,428,178
Ensembl chr 6:35,342,558...35,428,191 		JBrowse link
G PPARG peroxisome proliferator activated receptor gamma multiple interactions ISO rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARG mRNA] CTD PMID:25554529 NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356 		JBrowse link
G PPARGC1A PPARG coactivator 1 alpha multiple interactions ISO rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARGC1A mRNA] CTD PMID:25554529 NCBI chr 4:23,792,021...24,472,905
Ensembl chr 4:23,755,041...23,904,089 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 decreases expression EXP rebaudioside A results in decreased expression of PTGS2 mRNA CTD PMID:31655124 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit multiple interactions ISO rebaudioside A inhibits the reaction [Thioacetamide results in increased expression of RELA protein] CTD PMID:30883860 NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090 		JBrowse link
G SELE selectin E decreases expression EXP rebaudioside A results in decreased expression of SELE mRNA CTD PMID:31655124 NCBI chr 1:169,722,640...169,734,079
Ensembl chr 1:169,722,640...169,764,705 		JBrowse link
G SIRT1 sirtuin 1 multiple interactions ISO rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SIRT1 mRNA] CTD PMID:25554529 NCBI chr10:67,884,656...67,918,390
Ensembl chr10:67,884,656...67,918,390 		JBrowse link
G SLC27A1 solute carrier family 27 member 1 multiple interactions ISO rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SLC27A1 mRNA] CTD PMID:25554529 NCBI chr19:17,468,767...17,506,168
Ensembl chr19:17,468,769...17,506,168 		JBrowse link
G SLC2A2 solute carrier family 2 member 2 multiple interactions ISO rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SLC2A2 mRNA] CTD PMID:25554529 NCBI chr 3:170,996,347...171,026,720
Ensembl chr 3:170,996,347...171,026,743 		JBrowse link
G SMAD7 SMAD family member 7 multiple interactions ISO rebaudioside A inhibits the reaction [Thioacetamide results in decreased expression of SMAD7 protein] CTD PMID:30883860 NCBI chr18:48,919,853...48,950,965
Ensembl chr18:48,919,853...48,950,965 		JBrowse link
G SOD2 superoxide dismutase 2 multiple interactions ISO rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SOD2 mRNA] CTD PMID:25554529 NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529 		JBrowse link
G TGFB1 transforming growth factor beta 1 multiple interactions ISO rebaudioside A inhibits the reaction [Thioacetamide results in increased expression of TGFB1 protein] CTD PMID:30883860 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922 		JBrowse link
G TNF tumor necrosis factor multiple interactions ISO rebaudioside A inhibits the reaction [Thioacetamide results in increased expression of TNF protein] CTD PMID:30883860 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TNFSF10 TNF superfamily member 10 decreases expression EXP rebaudioside A results in decreased expression of TNFSF10 mRNA CTD PMID:31655124 NCBI chr 3:172,505,508...172,523,430
Ensembl chr 3:172,505,508...172,523,475 		JBrowse link
salicin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALB albumin multiple interactions EXP ALB protein binds to and affects the transport of salicin CTD PMID:8831264 NCBI chr 4:73,404,287...73,421,482
Ensembl chr 4:73,397,114...73,421,482 		JBrowse link
G TAS2R16 taste 2 receptor member 16 multiple interactions
increases activity		 EXP 4-((diethylamino)sulfonyl)benzoic acid inhibits the reaction [salicin results in increased activity of TAS2R16 protein]; Probenecid inhibits the reaction [salicin results in increased activity of TAS2R16 protein] CTD PMID:21629661 NCBI chr 7:122,994,704...122,995,700
Ensembl chr 7:122,994,704...122,995,700 		JBrowse link
scopolin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IDE insulin degrading enzyme multiple interactions EXP scopolin binds to and affects the activity of IDE protein CTD PMID:23146021 NCBI chr10:92,451,684...92,574,093
Ensembl chr10:92,451,684...92,574,096 		JBrowse link
G UROD uroporphyrinogen decarboxylase multiple interactions EXP scopolin binds to and affects the activity of UROD protein CTD PMID:23209648 NCBI chr 1:45,012,254...45,015,575
Ensembl chr 1:45,010,950...45,015,575 		JBrowse link
sinigrin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKR7A3 aldo-keto reductase family 7 member A3 increases activity ISO sinigrin results in increased activity of AKR7A3 protein CTD PMID:9328168 NCBI chr 1:19,274,229...19,288,770
Ensembl chr 1:19,282,573...19,288,770 		JBrowse link
G GSTA5 glutathione S-transferase alpha 5 increases activity ISO sinigrin results in increased activity of GSTA5 protein CTD PMID:9328168 NCBI chr 6:52,831,692...52,846,245
Ensembl chr 6:52,831,655...52,840,843 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit multiple interactions ISO sinigrin inhibits the reaction [TNF protein affects the localization of RELA protein] CTD PMID:28483571 NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090 		JBrowse link
G TNF tumor necrosis factor multiple interactions ISO sinigrin inhibits the reaction [TNF protein affects the localization of RELA protein]; sinigrin inhibits the reaction [TNF protein results in increased expression of VCAM1 mRNA]; sinigrin inhibits the reaction [TNF protein results in increased expression of VCAM1 protein] CTD PMID:28483571 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G VCAM1 vascular cell adhesion molecule 1 multiple interactions ISO sinigrin inhibits the reaction [TNF protein results in increased expression of VCAM1 mRNA]; sinigrin inhibits the reaction [TNF protein results in increased expression of VCAM1 protein] CTD PMID:28483571 NCBI chr 1:100,719,742...100,739,045
Ensembl chr 1:100,719,742...100,739,045 		JBrowse link
stevioside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACE angiotensin I converting enzyme decreases expression EXP stevioside results in decreased expression of ACE mRNA CTD PMID:31655124 NCBI chr17:63,477,061...63,498,373
Ensembl chr17:63,477,061...63,498,380 		JBrowse link
G ACHE acetylcholinesterase (Yt blood group) multiple interactions ISO stevioside inhibits the reaction [Scopolamine results in increased activity of ACHE protein] CTD PMID:20871768 NCBI chr 7:100,889,994...100,896,994
Ensembl chr 7:100,889,994...100,896,974 		JBrowse link
G ACOX1 acyl-CoA oxidase 1 multiple interactions ISO stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of ACOX1 mRNA] CTD PMID:25554529 NCBI chr17:75,941,507...75,979,166
Ensembl chr17:75,941,507...75,979,177 		JBrowse link
G ACP5 acid phosphatase 5, tartrate resistant decreases secretion ISO stevioside results in decreased secretion of ACP5 protein CTD PMID:21089163 NCBI chr19:11,574,660...11,578,975
Ensembl chr19:11,574,653...11,579,993 		JBrowse link
G AGTR1 angiotensin II receptor type 1 increases expression EXP stevioside results in increased expression of AGTR1 mRNA CTD PMID:31655124 NCBI chr 3:148,697,903...148,743,003
Ensembl chr 3:148,697,784...148,743,008 		JBrowse link
G ALOX5 arachidonate 5-lipoxygenase increases expression EXP stevioside results in increased expression of ALOX5 mRNA CTD PMID:31655124 NCBI chr10:45,374,216...45,446,117
Ensembl chr10:45,374,176...45,446,119 		JBrowse link
G BAX BCL2 associated X, apoptosis regulator decreases expression EXP stevioside results in decreased expression of BAX mRNA CTD PMID:31655124 NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798 		JBrowse link
G CALCA calcitonin related polypeptide alpha increases expression EXP stevioside results in increased expression of CALCA mRNA CTD PMID:31655124 NCBI chr11:14,966,668...14,972,351
Ensembl chr11:14,966,622...14,972,354 		JBrowse link
G CAT catalase multiple interactions ISO stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of CAT mRNA] CTD PMID:25554529 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060 		JBrowse link
G CCL2 C-C motif chemokine ligand 2 decreases expression EXP stevioside results in decreased expression of CCL2 mRNA CTD PMID:31655124 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208 		JBrowse link
G CFLAR CASP8 and FADD like apoptosis regulator decreases expression EXP stevioside results in decreased expression of CFLAR mRNA CTD PMID:31655124 NCBI chr 2:201,116,164...201,176,687
Ensembl chr 2:201,116,154...201,176,687 		JBrowse link
G CPT1A carnitine palmitoyltransferase 1A multiple interactions ISO stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of CPT1A mRNA] CTD PMID:25554529 NCBI chr11:68,754,620...68,844,277
Ensembl chr11:68,754,620...68,844,410 		JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 increases expression EXP stevioside results in increased expression of CYP1A1 mRNA CTD PMID:28887089 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536 		JBrowse link
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 increases expression EXP stevioside results in increased expression of CYP1A2 mRNA; stevioside results in increased expression of CYP1A2 protein CTD PMID:28887089 NCBI chr15:74,748,845...74,756,607
Ensembl chr15:74,748,845...74,756,607 		JBrowse link
G CYP1B1 cytochrome P450 family 1 subfamily B member 1 increases expression EXP stevioside results in increased expression of CYP1B1 mRNA CTD PMID:28887089 NCBI chr 2:38,067,509...38,076,151
Ensembl chr 2:38,066,973...38,109,902 		JBrowse link
G CYP2C9 cytochrome P450 family 2 subfamily C member 9 decreases expression EXP stevioside results in decreased expression of CYP2C9 mRNA CTD PMID:28887089 NCBI chr10:94,938,658...94,990,091
Ensembl chr10:94,938,658...94,990,091 		JBrowse link
G CYP3A4 cytochrome P450 family 3 subfamily A member 4 multiple interactions
increases expression		 EXP stevioside binds to and results in decreased activity of CYP3A4 protein
stevioside results in increased expression of CYP3A4 mRNA; stevioside results in increased expression of CYP3A4 protein		 CTD PMID:28887089 NCBI chr 7:99,756,967...99,784,184
Ensembl chr 7:99,756,960...99,784,248 		JBrowse link
G DGAT2 diacylglycerol O-acyltransferase 2 multiple interactions ISO stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of DGAT2 mRNA] CTD PMID:25554529 NCBI chr11:75,768,778...75,801,534
Ensembl chr11:75,759,512...75,801,535 		JBrowse link
G EDN1 endothelin 1 decreases expression EXP stevioside results in decreased expression of EDN1 mRNA CTD PMID:31655124 NCBI chr 6:12,230,516...12,297,194
Ensembl chr 6:12,290,361...12,297,194 		JBrowse link
G EDNRA endothelin receptor type A increases expression EXP stevioside results in increased expression of EDNRA mRNA CTD PMID:31655124 NCBI chr 4:147,481,097...147,544,954
Ensembl chr 4:147,480,917...147,544,954 		JBrowse link
G F2R coagulation factor II thrombin receptor decreases expression EXP stevioside results in decreased expression of F2R mRNA CTD PMID:31655124 NCBI chr 5:76,716,126...76,735,770
Ensembl chr 5:76,716,126...76,735,770 		JBrowse link
G FASLG Fas ligand increases expression EXP stevioside results in increased expression of FASLG mRNA CTD PMID:31655124 NCBI chr 1:172,659,103...172,666,876
Ensembl chr 1:172,659,103...172,666,876 		JBrowse link
G FGF1 fibroblast growth factor 1 increases expression EXP stevioside results in increased expression of FGF1 mRNA CTD PMID:31655124 NCBI chr 5:142,592,178...142,698,070
Ensembl chr 5:142,592,178...142,698,070 		JBrowse link
G FLT1 fms related receptor tyrosine kinase 1 decreases expression EXP stevioside results in decreased expression of FLT1 mRNA CTD PMID:31655124 NCBI chr13:28,300,346...28,495,128
Ensembl chr13:28,300,346...28,495,145 		JBrowse link
G FOXO1 forkhead box O1 multiple interactions ISO stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of FOXO1 mRNA] CTD PMID:25554529 NCBI chr13:40,555,667...40,666,641
Ensembl chr13:40,555,667...40,666,641 		JBrowse link
G G6PC1 glucose-6-phosphatase catalytic subunit 1 multiple interactions ISO stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of G6PC1 mRNA] CTD PMID:25554529 NCBI chr17:42,900,799...42,914,438
Ensembl chr17:42,900,797...42,914,438 		JBrowse link
G INSR insulin receptor multiple interactions ISO stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of INSR mRNA] CTD PMID:25554529 NCBI chr19:7,112,265...7,294,414
Ensembl chr19:7,112,255...7,294,414 		JBrowse link
G IRS1 insulin receptor substrate 1 multiple interactions ISO stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of IRS1 mRNA] CTD PMID:25554529 NCBI chr 2:226,731,312...226,799,820
Ensembl chr 2:226,731,312...226,799,820 		JBrowse link
G IRS2 insulin receptor substrate 2 multiple interactions ISO stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of IRS2 mRNA] CTD PMID:25554529 NCBI chr13:109,752,695...109,786,583
Ensembl chr13:109,752,695...109,786,583 		JBrowse link
G ITGAV integrin subunit alpha V decreases expression EXP stevioside results in decreased expression of ITGAV mRNA CTD PMID:31655124 NCBI chr 2:186,590,056...186,680,901
Ensembl chr 2:186,590,010...186,680,901 		JBrowse link
G KIT KIT proto-oncogene, receptor tyrosine kinase decreases expression EXP stevioside results in decreased expression of KIT mRNA CTD PMID:31655124 NCBI chr 4:54,657,957...54,740,715
Ensembl chr 4:54,657,267...54,740,783 		JBrowse link
G LDLR low density lipoprotein receptor multiple interactions ISO stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of ACOX1 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of CAT mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of CPT1A mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of DGAT2 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of FOXO1 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of G6PC1 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of INSR mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of IRS1 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of IRS2 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of LIPC mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of MTOR mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of NFKB1 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of NFKBIA mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PCK1 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PLIN2 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARA mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARD mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARG mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARGC1A mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SCD1 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SIRT1 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SLC27A1 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SLC2A2 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SOD2 mRNA] CTD PMID:25554529 NCBI chr19:11,089,463...11,133,820
Ensembl chr19:11,089,418...11,133,820 		JBrowse link
G LEP leptin multiple interactions ISO stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of ACOX1 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of CAT mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of CPT1A mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of DGAT2 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of FOXO1 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of G6PC1 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of INSR mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of IRS1 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of IRS2 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of LIPC mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of MTOR mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of NFKB1 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of NFKBIA mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PCK1 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PLIN2 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARA mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARD mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARG mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARGC1A mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SCD1 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SIRT1 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SLC27A1 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SLC2A2 mRNA]; stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SOD2 mRNA] CTD PMID:25554529 NCBI chr 7:128,241,278...128,257,629
Ensembl chr 7:128,241,278...128,257,629 		JBrowse link
G LIPC lipase C, hepatic type multiple interactions ISO stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of LIPC mRNA] CTD PMID:25554529 NCBI chr15:58,431,991...58,569,844
Ensembl chr15:58,410,569...58,569,844 		JBrowse link
G MMP9 matrix metallopeptidase 9 increases expression EXP stevioside results in increased expression of MMP9 mRNA CTD PMID:31655124 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561 		JBrowse link
G MTOR mechanistic target of rapamycin kinase multiple interactions ISO stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of MTOR mRNA] CTD PMID:25554529 NCBI chr 1:11,106,535...11,262,551
Ensembl chr 1:11,106,535...11,262,556 		JBrowse link
G NFKB1 nuclear factor kappa B subunit 1 multiple interactions ISO stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of NFKB1 mRNA] CTD PMID:25554529 NCBI chr 4:102,501,359...102,617,302
Ensembl chr 4:102,501,330...102,617,302 		JBrowse link
G NFKBIA NFKB inhibitor alpha multiple interactions ISO stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of NFKBIA mRNA] CTD PMID:25554529 NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749 		JBrowse link
G PCK1 phosphoenolpyruvate carboxykinase 1 multiple interactions ISO stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PCK1 mRNA] CTD PMID:25554529 NCBI chr20:57,561,110...57,568,121
Ensembl chr20:57,561,080...57,568,121 		JBrowse link
G PF4 platelet factor 4 increases expression EXP stevioside results in increased expression of PF4 mRNA CTD PMID:31655124 NCBI chr 4:73,980,811...73,982,124
Ensembl chr 4:73,980,811...73,982,027 		JBrowse link
G PLIN2 perilipin 2 multiple interactions ISO stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PLIN2 mRNA] CTD PMID:25554529 NCBI chr 9:19,108,388...19,127,492
Ensembl chr 9:19,108,375...19,149,290 		JBrowse link
G PPARA peroxisome proliferator activated receptor alpha multiple interactions ISO stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARA mRNA] CTD PMID:25554529 NCBI chr22:46,150,526...46,243,756
Ensembl chr22:46,150,521...46,243,755 		JBrowse link
G PPARD peroxisome proliferator activated receptor delta multiple interactions ISO stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARD mRNA] CTD PMID:25554529 NCBI chr 6:35,342,558...35,428,178
Ensembl chr 6:35,342,558...35,428,191 		JBrowse link
G PPARG peroxisome proliferator activated receptor gamma multiple interactions ISO stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARG mRNA] CTD PMID:25554529 NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356 		JBrowse link
G PPARGC1A PPARG coactivator 1 alpha multiple interactions ISO stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARGC1A mRNA] CTD PMID:25554529 NCBI chr 4:23,792,021...24,472,905
Ensembl chr 4:23,755,041...23,904,089 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 decreases expression EXP stevioside results in decreased expression of PTGS2 mRNA CTD PMID:31655124 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922 		JBrowse link
G SELE selectin E decreases expression EXP stevioside results in decreased expression of SELE mRNA CTD PMID:31655124 NCBI chr 1:169,722,640...169,734,079
Ensembl chr 1:169,722,640...169,764,705 		JBrowse link
G SIRT1 sirtuin 1 multiple interactions ISO stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SIRT1 mRNA] CTD PMID:25554529 NCBI chr10:67,884,656...67,918,390
Ensembl chr10:67,884,656...67,918,390 		JBrowse link
G SLC27A1 solute carrier family 27 member 1 multiple interactions ISO stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SLC27A1 mRNA] CTD PMID:25554529 NCBI chr19:17,468,767...17,506,168
Ensembl chr19:17,468,769...17,506,168 		JBrowse link
G SLC2A2 solute carrier family 2 member 2 multiple interactions ISO stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SLC2A2 mRNA] CTD PMID:25554529 NCBI chr 3:170,996,347...171,026,720
Ensembl chr 3:170,996,347...171,026,743 		JBrowse link
G SOD2 superoxide dismutase 2 multiple interactions ISO stevioside affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SOD2 mRNA] CTD PMID:25554529 NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529 		JBrowse link
G TNFSF10 TNF superfamily member 10 decreases expression EXP stevioside results in decreased expression of TNFSF10 mRNA CTD PMID:31655124 NCBI chr 3:172,505,508...172,523,430
Ensembl chr 3:172,505,508...172,523,475 		JBrowse link
syringin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAX BCL2 associated X, apoptosis regulator increases expression EXP syringin results in increased expression of BAX protein CTD PMID:35580997 NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798 		JBrowse link
G BCL2 BCL2 apoptosis regulator decreases expression EXP syringin results in decreased expression of BCL2 protein CTD PMID:35580997 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128 		JBrowse link
G BIRC5 baculoviral IAP repeat containing 5 decreases expression EXP syringin results in decreased expression of BIRC5 protein CTD PMID:35580997 NCBI chr17:78,214,253...78,225,635
Ensembl chr17:78,214,186...78,225,636 		JBrowse link
G CCL11 C-C motif chemokine ligand 11 multiple interactions ISO syringin inhibits the reaction [Ovalbumin results in increased expression of CCL11 protein] CTD PMID:33146439 NCBI chr17:34,285,742...34,288,334
Ensembl chr17:34,285,742...34,288,334 		JBrowse link
G CCND1 cyclin D1 increases expression EXP syringin results in increased expression of CCND1 protein CTD PMID:35580997 NCBI chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474 		JBrowse link
G CDH1 cadherin 1 increases expression EXP syringin results in increased expression of CDH1 protein CTD PMID:35580997 NCBI chr16:68,737,292...68,835,537
Ensembl chr16:68,737,292...68,835,537 		JBrowse link
G IFNG interferon gamma multiple interactions ISO syringin inhibits the reaction [Ovalbumin results in increased expression of IFNG protein] CTD PMID:33146439 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740 		JBrowse link
G IL13 interleukin 13 multiple interactions ISO syringin inhibits the reaction [Ovalbumin results in increased expression of IL13 protein] CTD PMID:33146439 NCBI chr 5:132,656,522...132,661,110
Ensembl chr 5:132,656,263...132,661,110 		JBrowse link
G IL4 interleukin 4 multiple interactions ISO syringin inhibits the reaction [Ovalbumin results in increased expression of IL4 protein] CTD PMID:33146439 NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678 		JBrowse link
G IL5 interleukin 5 multiple interactions ISO syringin inhibits the reaction [Ovalbumin results in increased expression of IL5 protein] CTD PMID:33146439 NCBI chr 5:132,541,445...132,556,815
Ensembl chr 5:132,541,445...132,556,838 		JBrowse link
G IL6 interleukin 6 multiple interactions ISO syringin inhibits the reaction [Ovalbumin results in increased expression of IL6 protein] CTD PMID:33146439 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G MPO myeloperoxidase multiple interactions ISO syringin inhibits the reaction [Ovalbumin results in increased activity of MPO protein] CTD PMID:33146439 NCBI chr17:58,269,855...58,280,935
Ensembl chr17:58,269,855...58,280,935 		JBrowse link
G NFKBIA NFKB inhibitor alpha multiple interactions ISO syringin inhibits the reaction [Ovalbumin results in increased expression of and results in increased phosphorylation of NFKBIA protein] CTD PMID:33146439 NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749 		JBrowse link
G PPARA peroxisome proliferator activated receptor alpha increases phosphorylation EXP syringin results in increased phosphorylation of PPARA protein CTD PMID:23691032 NCBI chr22:46,150,526...46,243,756
Ensembl chr22:46,150,521...46,243,755 		JBrowse link
G PRKAA1 protein kinase AMP-activated catalytic subunit alpha 1 decreases phosphorylation EXP syringin results in decreased phosphorylation of PRKAA1 protein CTD PMID:23691032 NCBI chr 5:40,759,389...40,798,374
Ensembl chr 5:40,759,389...40,798,374 		JBrowse link
G PRKAA2 protein kinase AMP-activated catalytic subunit alpha 2 decreases phosphorylation EXP syringin results in decreased phosphorylation of PRKAA2 protein CTD PMID:23691032 NCBI chr 1:56,645,314...56,715,335
Ensembl chr 1:56,645,314...56,715,335 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit multiple interactions ISO syringin inhibits the reaction [Ovalbumin results in increased expression of and results in increased phosphorylation of RELA protein] CTD PMID:33146439 NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090 		JBrowse link
G SQSTM1 sequestosome 1 decreases expression EXP syringin results in decreased expression of SQSTM1 protein CTD PMID:35580997 NCBI chr 5:179,806,393...179,838,078
Ensembl chr 5:179,806,398...179,838,078 		JBrowse link
G TNF tumor necrosis factor multiple interactions ISO syringin inhibits the reaction [Ovalbumin results in increased expression of TNF protein] CTD PMID:33146439 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TP53 tumor protein p53 increases expression EXP syringin results in increased expression of TP53 protein CTD PMID:35580997 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,546 		JBrowse link
tectoridin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACADM acyl-CoA dehydrogenase medium chain multiple interactions ISO tectoridin inhibits the reaction [Ethanol results in decreased expression of ACADM mRNA] CTD PMID:20637825 NCBI chr 1:75,724,709...75,763,679
Ensembl chr 1:75,724,431...75,787,575 		JBrowse link
G ACOX1 acyl-CoA oxidase 1 multiple interactions ISO tectoridin inhibits the reaction [Ethanol results in decreased expression of ACOX1 mRNA] CTD PMID:20637825 NCBI chr17:75,941,507...75,979,166
Ensembl chr17:75,941,507...75,979,177 		JBrowse link
G CPT1A carnitine palmitoyltransferase 1A multiple interactions ISO tectoridin inhibits the reaction [Ethanol results in decreased expression of CPT1A mRNA] CTD PMID:20637825 NCBI chr11:68,754,620...68,844,277
Ensembl chr11:68,754,620...68,844,410 		JBrowse link
G DGAT1 diacylglycerol O-acyltransferase 1 multiple interactions ISO tectoridin inhibits the reaction [Ethanol results in increased expression of DGAT1 mRNA] CTD PMID:20637825 NCBI chr 8:144,314,584...144,326,852
Ensembl chr 8:144,314,584...144,326,910 		JBrowse link
G DGAT2 diacylglycerol O-acyltransferase 2 multiple interactions ISO tectoridin inhibits the reaction [Ethanol results in increased expression of DGAT2 mRNA] CTD PMID:20637825 NCBI chr11:75,768,778...75,801,534
Ensembl chr11:75,759,512...75,801,535 		JBrowse link
G DPP4 dipeptidyl peptidase 4 multiple interactions ISO [Xiao-Ke-An results in increased abundance of tectoridin] which results in decreased activity of DPP4 protein CTD PMID:32535096 NCBI chr 2:161,992,245...162,074,215
Ensembl chr 2:161,992,245...162,074,394 		JBrowse link
G GPAM glycerol-3-phosphate acyltransferase, mitochondrial multiple interactions ISO tectoridin inhibits the reaction [Ethanol results in increased expression of GPAM mRNA] CTD PMID:20637825 NCBI chr10:112,149,865...112,227,677
Ensembl chr10:112,149,865...112,215,377 		JBrowse link
G PPARA peroxisome proliferator activated receptor alpha multiple interactions ISO tectoridin inhibits the reaction [Ethanol results in decreased expression of PPARA mRNA] CTD PMID:20637825 NCBI chr22:46,150,526...46,243,756
Ensembl chr22:46,150,521...46,243,755 		JBrowse link
teniposide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCC1 ATP binding cassette subfamily C member 1 (ABCC1 blood group) decreases response to substance ISO ABCC1 results in decreased susceptibility to Teniposide CTD PMID:8968083 NCBI chr16:15,949,143...16,143,053
Ensembl chr16:15,949,138...16,143,257 		JBrowse link
G AR androgen receptor multiple interactions EXP Teniposide binds to and results in decreased activity of AR protein CTD PMID:25752796 NCBI chr  X:67,544,021...67,730,619
Ensembl chr  X:67,544,021...67,730,619 		JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A increases expression EXP Teniposide results in increased expression of CDKN1A mRNA; Teniposide results in increased expression of CDKN1A protein CTD PMID:25914138 NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,337 		JBrowse link
G CETP cholesteryl ester transfer protein multiple interactions
increases expression		 EXP [Tretinoin co-treated with Teniposide] results in increased expression of CETP mRNA; CETP protein promotes the reaction [Teniposide results in decreased abundance of Triglycerides]; NR1H2 mutant form inhibits the reaction [Teniposide results in increased expression of CETP mRNA]; NR1H3 mutant form inhibits the reaction [Teniposide results in increased expression of CETP mRNA]; Teniposide promotes the reaction [CETP protein results in decreased abundance of Cholesterol, HDL]; Teniposide promotes the reaction [CETP protein results in decreased abundance of Cholesterol]; Teniposide promotes the reaction [CETP protein results in decreased abundance of Triglycerides]; Teniposide promotes the reaction [NR1H2 protein results in increased expression of CETP mRNA]; Teniposide promotes the reaction [NR1H3 protein results in increased expression of CETP mRNA]; Teniposide promotes the reaction [RXRA protein results in increased expression of CETP mRNA]; Teniposide results in increased expression of and results in increased secretion of CETP protein; Tretinoin promotes the reaction [Teniposide promotes the reaction [RXRA protein results in increased expression of CETP mRNA]]; Tretinoin promotes the reaction [Teniposide results in increased expression of CETP protein] CTD PMID:25914138 NCBI chr16:56,961,950...56,983,845
Ensembl chr16:56,961,923...56,983,845 		JBrowse link
G CYP3A4 cytochrome P450 family 3 subfamily A member 4 multiple interactions
decreases methylation		 EXP Cyclosporine inhibits the reaction [CYP3A4 protein results in decreased methylation of Teniposide]; Dexamethasone inhibits the reaction [CYP3A4 protein results in decreased methylation of Teniposide]; Erythromycin inhibits the reaction [CYP3A4 protein results in decreased methylation of Teniposide]; Midazolam inhibits the reaction [CYP3A4 protein results in decreased methylation of Teniposide] CTD PMID:8114683 NCBI chr 7:99,756,967...99,784,184
Ensembl chr 7:99,756,960...99,784,248 		JBrowse link
G CYP3A5 cytochrome P450 family 3 subfamily A member 5 decreases methylation EXP CYP3A5 protein results in decreased methylation of Teniposide CTD PMID:8114683 NCBI chr 7:99,648,194...99,679,996
Ensembl chr 7:99,648,194...99,679,996 		JBrowse link
G ESR1 estrogen receptor 1 multiple interactions EXP Teniposide binds to and results in decreased activity of ESR1 protein CTD PMID:25752796 NCBI chr 6:151,656,672...152,129,619
Ensembl chr 6:151,656,691...152,129,619 		JBrowse link
G ESR2 estrogen receptor 2 multiple interactions EXP Teniposide binds to and results in decreased activity of ESR2 protein CTD PMID:25752796 NCBI chr14:64,226,707...64,338,613
Ensembl chr14:64,084,232...64,338,112 		JBrowse link
G FGF2 fibroblast growth factor 2 decreases response to substance EXP FGF2 protein results in decreased susceptibility to Teniposide CTD PMID:20221717 NCBI chr 4:122,826,682...122,898,236
Ensembl chr 4:122,826,682...122,898,236 		JBrowse link
G GSTP1 glutathione S-transferase pi 1 multiple interactions EXP Teniposide inhibits the reaction [GSTP1 protein results in increased metabolism of 1-chloro-2,4-dinitrobenzene-glutathione conjugate] CTD PMID:23769903 NCBI chr11:67,583,812...67,586,653
Ensembl chr11:67,583,742...67,586,656 		JBrowse link
G MIR135B microRNA 135b decreases response to substance EXP MIR135B mRNA results in decreased susceptibility to Teniposide CTD PMID:27570640 NCBI chr 1:205,448,302...205,448,398
Ensembl chr 1:205,448,302...205,448,398 		JBrowse link
G MIR196B microRNA 196b decreases response to substance EXP MIR196B mRNA results in decreased susceptibility to Teniposide CTD PMID:27570640 NCBI chr 7:27,169,480...27,169,563
Ensembl chr 7:27,169,480...27,169,563 		JBrowse link
G MTTP microsomal triglyceride transfer protein decreases expression
multiple interactions		 ISO Teniposide results in decreased expression of MTTP mRNA
Teniposide promotes the reaction [CETP protein results in decreased expression of MTTP mRNA]		 CTD PMID:25914138 NCBI chr 4:99,564,130...99,623,997
Ensembl chr 4:99,564,081...99,623,997 		JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor decreases expression EXP Teniposide results in decreased expression of MYC mRNA; Teniposide results in decreased expression of MYC protein CTD PMID:11585056 NCBI chr 8:127,735,434...127,742,951
Ensembl chr 8:127,735,434...127,742,951 		JBrowse link
G NR1H2 nuclear receptor subfamily 1 group H member 2 multiple interactions
affects localization
affects response to substance		 EXP NR1H2 mutant form inhibits the reaction [Teniposide results in increased expression of CETP mRNA]; Teniposide promotes the reaction [NR1H2 protein results in increased expression of CETP mRNA]
Teniposide affects the localization of NR1H2 protein
NR1H2 protein affects the susceptibility to Teniposide		 CTD PMID:25914138 NCBI chr19:50,376,457...50,383,388
Ensembl chr19:50,329,653...50,383,388 		JBrowse link
G NR1H3 nuclear receptor subfamily 1 group H member 3 multiple interactions
increases expression
affects response to substance		 EXP NR1H3 mutant form inhibits the reaction [Teniposide results in increased expression of CETP mRNA]; Teniposide promotes the reaction [NR1H3 protein results in increased expression of CETP mRNA]; Teniposide results in increased expression of and affects the localization of NR1H3 protein
Teniposide results in increased expression of NR1H3 mRNA
NR1H3 protein affects the susceptibility to Teniposide		 CTD PMID:25914138 NCBI chr11:47,248,300...47,269,033
Ensembl chr11:47,248,300...47,269,033 		JBrowse link
G NRIP1 nuclear receptor interacting protein 1 decreases expression EXP Teniposide results in decreased expression of NRIP1 mRNA; Teniposide results in decreased expression of NRIP1 protein CTD PMID:25914138 NCBI chr21:14,961,235...15,065,936
Ensembl chr21:14,961,235...15,065,936 		JBrowse link
G ODC1 ornithine decarboxylase 1 decreases expression EXP Teniposide results in decreased expression of ODC1 protein CTD PMID:11585056 NCBI chr 2:10,439,968...10,448,327
Ensembl chr 2:10,439,968...10,448,327 		JBrowse link
G PGR progesterone receptor multiple interactions EXP Teniposide binds to and results in decreased activity of PGR protein CTD PMID:25752796 NCBI chr11:101,029,624...101,129,813
Ensembl chr11:101,029,624...101,129,813 		JBrowse link
G RXRA retinoid X receptor alpha multiple interactions EXP Teniposide promotes the reaction [RXRA protein results in increased expression of CETP mRNA]; Tretinoin promotes the reaction [Teniposide promotes the reaction [RXRA protein results in increased expression of CETP mRNA]] CTD PMID:25914138 NCBI chr 9:134,326,455...134,440,585
Ensembl chr 9:134,317,098...134,440,585 		JBrowse link
G SLCO2B1 solute carrier organic anion transporter family member 2B1 multiple interactions EXP Teniposide inhibits the reaction [SLCO2B1 protein results in increased uptake of Cascade Blue] CTD PMID:30863990 NCBI chr11:75,151,107...75,206,549
Ensembl chr11:75,100,563...75,206,549 		JBrowse link
G THRA thyroid hormone receptor alpha multiple interactions EXP Teniposide binds to and results in decreased activity of THRA protein CTD PMID:25752796 NCBI chr17:40,062,193...40,093,867
Ensembl chr17:40,058,290...40,093,867 		JBrowse link
G THRB thyroid hormone receptor beta multiple interactions EXP Teniposide binds to and results in decreased activity of THRB protein CTD PMID:25752796 NCBI chr 3:24,117,153...24,495,708
Ensembl chr 3:24,117,153...24,495,756 		JBrowse link
G TOP2A DNA topoisomerase II alpha multiple interactions EXP TOP2A results in decreased susceptibility to [Cisplatin co-treated with Teniposide] CTD PMID:11325482 NCBI chr17:40,388,525...40,417,896
Ensembl chr17:40,388,525...40,417,896 		JBrowse link
trans-piceid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCC2 ATP binding cassette subfamily C member 2 affects export EXP ABCC2 protein affects the export of polydatin CTD PMID:15686436 NCBI chr10:99,782,640...99,852,594
Ensembl chr10:99,782,640...99,852,594 		JBrowse link
G ABCG2 ATP binding cassette subfamily G member 2 (JR blood group) multiple interactions ISO polydatin inhibits the reaction [potassium oxonate results in increased expression of ABCG2 protein] CTD PMID:22865646 NCBI chr 4:88,090,264...88,231,626
Ensembl chr 4:88,090,150...88,231,628 		JBrowse link
G AGT angiotensinogen multiple interactions ISO polydatin inhibits the reaction [AGT protein modified form results in increased expression of CYBB mRNA]; polydatin inhibits the reaction [AGT protein modified form results in increased expression of CYBB protein]; polydatin inhibits the reaction [AGT protein modified form results in increased expression of MYH7 mRNA]; polydatin inhibits the reaction [AGT protein modified form results in increased expression of NOX4 mRNA]; polydatin inhibits the reaction [AGT protein modified form results in increased expression of NOX4 protein]; polydatin inhibits the reaction [AGT protein modified form results in increased expression of NPPA mRNA]; polydatin inhibits the reaction [AGT protein modified form results in increased expression of TGFB1 protein] CTD PMID:25488910 NCBI chr 1:230,702,523...230,745,583
Ensembl chr 1:230,690,776...230,745,576 		JBrowse link
G AHR aryl hydrocarbon receptor decreases localization
multiple interactions		 EXP polydatin results in decreased localization of AHR protein
polydatin promotes the reaction [6-formylindolo(3,2-b)carbazole results in increased localization of AHR protein]		 CTD PMID:21756928 NCBI chr 7:17,298,652...17,346,147
Ensembl chr 7:16,916,359...17,346,152 		JBrowse link
G ARNT aryl hydrocarbon receptor nuclear translocator increases localization EXP polydatin results in increased localization of ARNT protein CTD PMID:21756928 NCBI chr 1:150,809,713...150,876,599
Ensembl chr 1:150,809,713...150,876,708 		JBrowse link
G ATG5 autophagy related 5 multiple interactions EXP polydatin inhibits the reaction [Rotenone results in decreased expression of ATG5 protein] CTD PMID:31926197 NCBI chr 6:106,184,476...106,325,760
Ensembl chr 6:106,045,423...106,325,791 		JBrowse link
G BCL2 BCL2 apoptosis regulator multiple interactions ISO
EXP		 cyclopamine inhibits the reaction [polydatin promotes the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of BCL2 mRNA]]; polydatin promotes the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of BCL2 mRNA]
polydatin inhibits the reaction [Dopamine results in decreased expression of BCL2 protein]		 CTD PMID:27481074 PMID:28980048 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128 		JBrowse link
G CAT catalase multiple interactions ISO cyclopamine inhibits the reaction [polydatin inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in decreased activity of CAT protein]]; polydatin inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in decreased activity of CAT protein]
polydatin inhibits the reaction [Arsenic Trioxide results in decreased activity of CAT protein]		 CTD PMID:27481074 PMID:29130132 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060 		JBrowse link
G CCL2 C-C motif chemokine ligand 2 multiple interactions
decreases secretion
decreases expression		 EXP polydatin inhibits the reaction [leptomycin B results in increased secretion of CCL2 protein]; polydatin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of CCL2 mRNA]; polydatin inhibits the reaction [PD168393 results in increased expression of CCL2 mRNA]
polydatin results in decreased secretion of CCL2 protein
polydatin results in decreased expression of CCL2 mRNA		 CTD PMID:21756928 PMID:21967610 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208 		JBrowse link
G CCND1 cyclin D1 multiple interactions ISO cyclopamine inhibits the reaction [polydatin promotes the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CCND1 mRNA]]; polydatin promotes the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CCND1 mRNA] CTD PMID:27481074 NCBI chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474 		JBrowse link
G CCND2 cyclin D2 multiple interactions ISO cyclopamine inhibits the reaction [polydatin promotes the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CCND2 mRNA]]; polydatin promotes the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CCND2 mRNA] CTD PMID:27481074 NCBI chr12:4,273,762...4,305,353
Ensembl chr12:4,269,771...4,305,353 		JBrowse link
G CXCL10 C-X-C motif chemokine ligand 10 multiple interactions
decreases secretion
decreases expression		 EXP [polydatin co-treated with TGFA protein] results in increased expression of CXCL10 mRNA; polydatin inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased secretion of CXCL10 protein]; polydatin inhibits the reaction [PD168393 results in increased expression of CXCL10 mRNA]
polydatin results in decreased secretion of CXCL10 protein
polydatin results in decreased expression of CXCL10 mRNA		 CTD PMID:21756928 PMID:21967610 NCBI chr 4:76,021,118...76,023,497
Ensembl chr 4:76,021,118...76,023,497 		JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 multiple interactions
increases secretion
decreases expression		 EXP [polydatin co-treated with TGFA protein] results in increased expression of CXCL8 mRNA; polydatin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of CXCL8 mRNA]; polydatin promotes the reaction [[TNF protein co-treated with IFNG protein] results in increased secretion of CXCL8 protein]
polydatin results in increased secretion of CXCL8 protein
polydatin results in decreased expression of CXCL8 mRNA		 CTD PMID:21756928 PMID:21967610 NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716 		JBrowse link
G CYBB cytochrome b-245 beta chain multiple interactions ISO polydatin inhibits the reaction [AGT protein modified form results in increased expression of CYBB mRNA]; polydatin inhibits the reaction [AGT protein modified form results in increased expression of CYBB protein] CTD PMID:25488910 NCBI chr  X:37,780,059...37,813,461
Ensembl chr  X:37,780,018...37,813,461 		JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 increases expression EXP polydatin results in increased expression of CYP1A1 mRNA CTD PMID:21756928 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536 		JBrowse link
G EGFR epidermal growth factor receptor multiple interactions EXP polydatin inhibits the reaction [TGFA protein affects the localization of EGFR protein] CTD PMID:21967610 NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628 		JBrowse link
G ESR2 estrogen receptor 2 multiple interactions ISO ESR2 gene mutant form inhibits the reaction [polydatin results in increased expression of SOD2 protein] CTD PMID:24361291 NCBI chr14:64,226,707...64,338,613
Ensembl chr14:64,084,232...64,338,112 		JBrowse link
G G6PD glucose-6-phosphate dehydrogenase decreases activity EXP polydatin results in decreased activity of G6PD protein CTD PMID:25130191 NCBI chr  X:154,531,390...154,547,569
Ensembl chr  X:154,517,825...154,547,572 		JBrowse link
G GLI1 GLI family zinc finger 1 multiple interactions ISO cyclopamine inhibits the reaction [polydatin promotes the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of GLI1 mRNA]]; cyclopamine inhibits the reaction [polydatin promotes the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased localization of GLI1 protein]]; polydatin promotes the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of GLI1 mRNA]; polydatin promotes the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased localization of GLI1 protein] CTD PMID:27481074 NCBI chr12:57,459,785...57,472,268
Ensembl chr12:57,459,785...57,472,268 		JBrowse link
G HLCS holocarboxylase synthetase decreases activity EXP polydatin results in decreased activity of HLCS protein CTD PMID:26303405 NCBI chr21:36,748,625...36,990,211
Ensembl chr21:36,748,626...36,990,236 		JBrowse link
G IFNG interferon gamma multiple interactions EXP polydatin inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of MAPK1 protein]; polydatin inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of MAPK3 protein]; polydatin inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of RELA protein]; polydatin inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased secretion of CXCL10 protein]; polydatin promotes the reaction [[TNF protein co-treated with IFNG protein] results in increased secretion of CXCL8 protein] CTD PMID:21756928 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740 		JBrowse link
G IL1B interleukin 1 beta multiple interactions ISO polydatin inhibits the reaction [Arsenic Trioxide results in increased expression of IL1B mRNA] CTD PMID:29130132 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL4 interleukin 4 multiple interactions ISO polydatin inhibits the reaction [OVAL protein results in increased secretion of IL4 protein] CTD PMID:23840142 NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678 		JBrowse link
G IL6 interleukin 6 multiple interactions
decreases expression		 EXP polydatin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL6 mRNA]
polydatin results in decreased expression of IL6 mRNA		 CTD PMID:21756928 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G KEAP1 kelch like ECH associated protein 1 multiple interactions EXP
ISO		 polydatin inhibits the reaction [Hydrogen Peroxide results in increased expression of KEAP1 protein]
polydatin inhibits the reaction [TSHR protein results in increased expression of KEAP1 protein]		 CTD PMID:31705858 NCBI chr19:10,486,125...10,503,356
Ensembl chr19:10,486,125...10,503,558 		JBrowse link
G LCT lactase increases hydrolysis ISO LCT protein results in increased hydrolysis of polydatin analog CTD PMID:17009167 NCBI chr 2:135,787,850...135,837,184
Ensembl chr 2:135,787,850...135,837,184 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 multiple interactions
increases phosphorylation
decreases phosphorylation		 EXP polydatin inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of MAPK1 protein]; U 0126 inhibits the reaction [polydatin results in increased phosphorylation of MAPK1 protein]
polydatin results in decreased phosphorylation of MAPK1 protein		 CTD PMID:21756928 PMID:28980048 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 multiple interactions
increases phosphorylation
decreases phosphorylation		 EXP polydatin inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of MAPK3 protein]; U 0126 inhibits the reaction [polydatin results in increased phosphorylation of MAPK3 protein]
polydatin results in decreased phosphorylation of MAPK3 protein		 CTD PMID:21756928 PMID:28980048 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506 		JBrowse link
G MAPK7 mitogen-activated protein kinase 7 multiple interactions
increases phosphorylation		 EXP XMD 8-92 inhibits the reaction [polydatin results in increased phosphorylation of MAPK7 protein] CTD PMID:28980048 NCBI chr17:19,377,750...19,383,544
Ensembl chr17:19,377,721...19,383,544 		JBrowse link
G MFN2 mitofusin 2 multiple interactions EXP polydatin inhibits the reaction [Rotenone results in increased expression of MFN2 protein] CTD PMID:31926197 NCBI chr 1:11,980,444...12,013,508
Ensembl chr 1:11,980,181...12,015,211 		JBrowse link
G MTOR mechanistic target of rapamycin kinase multiple interactions EXP polydatin inhibits the reaction [Rotenone results in increased phosphorylation of MTOR protein] CTD PMID:31926197 NCBI chr 1:11,106,535...11,262,551
Ensembl chr 1:11,106,535...11,262,556 		JBrowse link
G MYH7 myosin heavy chain 7 multiple interactions ISO polydatin inhibits the reaction [AGT protein modified form results in increased expression of MYH7 mRNA] CTD PMID:25488910 NCBI chr14:23,412,740...23,435,660
Ensembl chr14:23,412,740...23,435,660 		JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 multiple interactions EXP
ISO		 [polydatin co-treated with Hydrogen Peroxide] results in increased expression of NFE2L2 protein; NFE2L2 protein affects the reaction [[polydatin co-treated with Hydrogen Peroxide] results in increased expression of NFE2L2 protein]; NFE2L2 protein affects the reaction [polydatin inhibits the reaction [Hydrogen Peroxide results in decreased expression of NQO1 protein]]
polydatin inhibits the reaction [TSHR protein results in decreased expression of NFE2L2 protein]		 CTD PMID:31705858 NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756 		JBrowse link
G NOX4 NADPH oxidase 4 multiple interactions ISO polydatin inhibits the reaction [AGT protein modified form results in increased expression of NOX4 mRNA]; polydatin inhibits the reaction [AGT protein modified form results in increased expression of NOX4 protein] CTD PMID:25488910 NCBI chr11:89,324,353...89,589,557
Ensembl chr11:89,324,353...89,498,187 		JBrowse link
G NPPA natriuretic peptide A multiple interactions ISO polydatin inhibits the reaction [2,2'-dipyridyl disulfide results in increased expression of NPPA protein]; polydatin inhibits the reaction [AGT protein modified form results in increased expression of NPPA mRNA]; polydatin inhibits the reaction [Phenylephrine results in increased expression of NPPA protein] CTD PMID:25449040 PMID:25488910 NCBI chr 1:11,845,709...11,847,783
Ensembl chr 1:11,845,709...11,848,345 		JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 multiple interactions EXP
ISO		 NFE2L2 protein affects the reaction [polydatin inhibits the reaction [Hydrogen Peroxide results in decreased expression of NQO1 protein]]; polydatin inhibits the reaction [Hydrogen Peroxide results in decreased expression of NQO1 protein]
polydatin inhibits the reaction [TSHR protein results in decreased expression of NQO1 protein]		 CTD PMID:31705858 NCBI chr16:69,709,401...69,726,560
Ensembl chr16:69,706,996...69,726,668 		JBrowse link
G ORAI1 ORAI calcium release-activated calcium modulator 1 affects response to substance ISO ORAI1 protein affects the susceptibility to polydatin CTD PMID:22959927 NCBI chr12:121,626,530...121,643,109
Ensembl chr12:121,626,509...121,643,218 		JBrowse link
G PARK7 Parkinsonism associated deglycase multiple interactions EXP [PRKN protein affects the susceptibility to polydatin] which results in increased expression of PARK7 protein; polydatin inhibits the reaction [Rotenone results in increased expression of PARK7 protein] CTD PMID:31926197 NCBI chr 1:7,961,711...7,985,505
Ensembl chr 1:7,954,291...7,985,505 		JBrowse link
G PDE5A phosphodiesterase 5A decreases activity EXP polydatin results in decreased activity of PDE5A protein CTD PMID:15769121 NCBI chr 4:119,494,403...119,628,804
Ensembl chr 4:119,494,397...119,628,804 		JBrowse link
G PPARGC1B PPARG coactivator 1 beta decreases expression EXP polydatin results in decreased expression of PPARGC1B protein CTD PMID:31926197 NCBI chr 5:149,730,310...149,857,959
Ensembl chr 5:149,730,298...149,855,022 		JBrowse link
G PPP1R12A protein phosphatase 1 regulatory subunit 12A multiple interactions ISO polydatin inhibits the reaction [2,2'-dipyridyl disulfide results in increased phosphorylation of PPP1R12A protein]; polydatin inhibits the reaction [Phenylephrine results in increased phosphorylation of PPP1R12A protein] CTD PMID:25449040 NCBI chr12:79,773,563...79,935,460
Ensembl chr12:79,773,563...79,935,460 		JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase affects response to substance
multiple interactions		 EXP PRKN protein affects the susceptibility to polydatin
[PRKN protein affects the susceptibility to polydatin] which results in increased expression of PARK7 protein		 CTD PMID:31926197 NCBI chr 6:161,347,417...162,727,766
Ensembl chr 6:161,347,417...162,727,775 		JBrowse link
G PTGS1 prostaglandin-endoperoxide synthase 1 decreases activity ISO polydatin results in decreased activity of PTGS1 protein CTD PMID:11962253 NCBI chr 9:122,370,533...122,395,703
Ensembl chr 9:122,370,530...122,395,703 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 multiple interactions
decreases activity		 EXP
ISO		 [polydatin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of PTGS2 mRNA
polydatin results in decreased activity of PTGS2 protein		 CTD PMID:11962253 PMID:21756928 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit multiple interactions EXP
ISO		 polydatin inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of RELA protein]; polydatin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased phosphorylation of RELA protein]
polydatin inhibits the reaction [Arsenic Trioxide results in increased expression of RELA mRNA]		 CTD PMID:21756928 PMID:29130132 NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090 		JBrowse link
G RHOA ras homolog family member A multiple interactions ISO polydatin inhibits the reaction [Phenylephrine results in increased activity of RHOA protein] CTD PMID:25449040 NCBI chr 3:49,359,145...49,411,976
Ensembl chr 3:49,359,139...49,412,998 		JBrowse link
G SHH sonic hedgehog signaling molecule multiple interactions ISO polydatin promotes the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of and results in increased secretion of SHH protein] CTD PMID:27481074 NCBI chr 7:155,799,980...155,812,463
Ensembl chr 7:155,799,980...155,812,463 		JBrowse link
G SIRT1 sirtuin 1 multiple interactions EXP polydatin inhibits the reaction [Rotenone results in decreased expression of SIRT1 protein] CTD PMID:31926197 NCBI chr10:67,884,656...67,918,390
Ensembl chr10:67,884,656...67,918,390 		JBrowse link
G SLC22A1 solute carrier family 22 member 1 multiple interactions ISO polydatin inhibits the reaction [potassium oxonate results in decreased expression of SLC22A1 protein] CTD PMID:22865646 NCBI chr 6:160,121,815...160,158,718
Ensembl chr 6:160,121,815...160,158,718 		JBrowse link
G SLC22A12 solute carrier family 22 member 12 multiple interactions ISO polydatin inhibits the reaction [potassium oxonate results in increased expression of SLC22A12 protein] CTD PMID:22865646 NCBI chr11:64,591,220...64,602,344
Ensembl chr11:64,590,641...64,602,353 		JBrowse link
G SLC22A4 solute carrier family 22 member 4 multiple interactions ISO polydatin inhibits the reaction [potassium oxonate results in decreased expression of SLC22A4 protein] CTD PMID:22865646 NCBI chr 5:132,294,394...132,344,190
Ensembl chr 5:132,294,394...132,344,190 		JBrowse link
G SLC22A5 solute carrier family 22 member 5 multiple interactions ISO polydatin inhibits the reaction [potassium oxonate results in decreased expression of SLC22A5 protein] CTD PMID:22865646 NCBI chr 5:132,369,710...132,395,612
Ensembl chr 5:132,369,710...132,395,613 		JBrowse link
G SLC22A6 solute carrier family 22 member 6 multiple interactions ISO polydatin inhibits the reaction [potassium oxonate results in decreased expression of SLC22A6 protein] CTD PMID:22865646 NCBI chr11:62,976,597...62,984,967
Ensembl chr11:62,936,385...62,984,967 		JBrowse link
G SLC2A9 solute carrier family 2 member 9 multiple interactions ISO polydatin inhibits the reaction [potassium oxonate results in increased expression of SLC2A9 protein] CTD PMID:22865646 NCBI chr 4:9,771,025...10,040,270
Ensembl chr 4:9,771,153...10,054,936 		JBrowse link
G SLC5A1 solute carrier family 5 member 1 affects uptake EXP SLC5A1 protein affects the uptake of polydatin CTD PMID:15686436 NCBI chr22:32,043,261...32,113,029
Ensembl chr22:32,043,261...32,113,029 		JBrowse link
G SOD2 superoxide dismutase 2 multiple interactions
increases expression		 EXP
ISO		 polydatin results in increased expression of and results in increased activity of SOD2 protein
polydatin results in increased expression of SOD2 protein
ESR2 gene mutant form inhibits the reaction [polydatin results in increased expression of SOD2 protein]; fulvestrant inhibits the reaction [polydatin results in increased expression of SOD2 protein]		 CTD PMID:24361291 NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529 		JBrowse link
G SQSTM1 sequestosome 1 multiple interactions EXP polydatin promotes the reaction [Rotenone results in decreased expression of SQSTM1 protein] CTD PMID:31926197 NCBI chr 5:179,806,393...179,838,078
Ensembl chr 5:179,806,398...179,838,078 		JBrowse link
G TGFA transforming growth factor alpha multiple interactions EXP [polydatin co-treated with TGFA protein] results in increased expression of CXCL10 mRNA; [polydatin co-treated with TGFA protein] results in increased expression of CXCL8 mRNA; polydatin inhibits the reaction [TGFA protein affects the localization of EGFR protein] CTD PMID:21756928 PMID:21967610 NCBI chr 2:70,447,284...70,553,826
Ensembl chr 2:70,447,284...70,554,193 		JBrowse link
G TGFB1 transforming growth factor beta 1 multiple interactions ISO polydatin inhibits the reaction [AGT protein modified form results in increased expression of TGFB1 protein] CTD PMID:25488910 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922 		JBrowse link
G TNF tumor necrosis factor multiple interactions
decreases expression		 EXP
ISO		 polydatin inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of MAPK1 protein]; polydatin inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of MAPK3 protein]; polydatin inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of RELA protein]; polydatin inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased secretion of CXCL10 protein]; polydatin promotes the reaction [[TNF protein co-treated with IFNG protein] results in increased secretion of CXCL8 protein]
polydatin inhibits the reaction [Arsenic Trioxide results in increased expression of TNF mRNA]
polydatin results in decreased expression of TNF mRNA		 CTD PMID:21756928 PMID:29130132 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TP53 tumor protein p53 multiple interactions ISO polydatin inhibits the reaction [Arsenic Trioxide results in increased expression of TP53 mRNA] CTD PMID:29130132 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,546 		JBrowse link
G TSHR thyroid stimulating hormone receptor multiple interactions ISO polydatin inhibits the reaction [TSHR protein results in decreased expression of NFE2L2 protein]; polydatin inhibits the reaction [TSHR protein results in decreased expression of NQO1 protein]; polydatin inhibits the reaction [TSHR protein results in increased expression of KEAP1 protein] CTD PMID:31705858 NCBI chr14:80,955,621...81,146,306
Ensembl chr14:80,954,989...81,146,306 		JBrowse link
G TUG1 taurine up-regulated 1 decreases expression EXP polydatin results in decreased expression of TUG1 mRNA CTD PMID:30974157 NCBI chr22:30,969,265...30,979,395
Ensembl chr22:30,969,245...30,979,395 		JBrowse link
G UGT1A1 UDP glucuronosyltransferase family 1 member A1 increases hydrolysis EXP UGT1A1 protein results in increased hydrolysis of polydatin metabolite CTD PMID:17009167 NCBI chr 2:233,760,270...233,773,300
Ensembl chr 2:233,760,270...233,773,300 		JBrowse link
G ULK1 unc-51 like autophagy activating kinase 1 multiple interactions EXP polydatin inhibits the reaction [Rotenone results in increased phosphorylation of ULK1 protein] CTD PMID:31926197 NCBI chr12:131,894,622...131,923,150
Ensembl chr12:131,894,622...131,923,150 		JBrowse link
G UMOD uromodulin multiple interactions ISO polydatin inhibits the reaction [potassium oxonate results in increased expression of and results in decreased secretion of UMOD protein] CTD PMID:22865646 NCBI chr16:20,333,051...20,356,301
Ensembl chr16:20,333,051...20,356,301 		JBrowse link
trans-rhaponticin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CAT catalase multiple interactions ISO rhapontin inhibits the reaction [Streptozocin results in decreased activity of CAT protein] CTD PMID:32662907 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060 		JBrowse link
G HMOX1 heme oxygenase 1 multiple interactions ISO rhapontin inhibits the reaction [Streptozocin results in decreased expression of HMOX1 mRNA]; rhapontin inhibits the reaction [Streptozocin results in decreased expression of HMOX1 protein] CTD PMID:32662907 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214 		JBrowse link
G IL10 interleukin 10 multiple interactions ISO rhapontin inhibits the reaction [Streptozocin results in decreased expression of IL10 mRNA]; rhapontin inhibits the reaction [Streptozocin results in decreased expression of IL10 protein] CTD PMID:32662907 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541 		JBrowse link
G INS-IGF2 INS-IGF2 readthrough multiple interactions ISO rhapontin inhibits the reaction [Streptozocin results in decreased expression of INS1 protein] CTD PMID:32662907 NCBI chr11:2,129,117...2,161,209
Ensembl chr11:2,132,538...2,161,209 		JBrowse link
G KEAP1 kelch like ECH associated protein 1 multiple interactions ISO rhapontin inhibits the reaction [Streptozocin results in increased expression of KEAP1 mRNA]; rhapontin inhibits the reaction [Streptozocin results in increased expression of KEAP1 protein] CTD PMID:32662907 NCBI chr19:10,486,125...10,503,356
Ensembl chr19:10,486,125...10,503,558 		JBrowse link
G MMP2 matrix metallopeptidase 2 multiple interactions ISO rhapontin inhibits the reaction [Streptozocin results in increased expression of MMP2 mRNA] CTD PMID:32662907 NCBI chr16:55,478,830...55,506,691
Ensembl chr16:55,389,700...55,506,691 		JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 multiple interactions ISO rhapontin inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 mRNA]; rhapontin inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 protein] CTD PMID:32662907 NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756 		JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 multiple interactions ISO rhapontin inhibits the reaction [Streptozocin results in decreased expression of NQO1 mRNA] CTD PMID:32662907 NCBI chr16:69,709,401...69,726,560
Ensembl chr16:69,706,996...69,726,668 		JBrowse link
G TIMP1 TIMP metallopeptidase inhibitor 1 multiple interactions ISO rhapontin inhibits the reaction [Streptozocin results in decreased expression of TIMP1 mRNA] CTD PMID:32662907 NCBI chr  X:47,582,436...47,586,789
Ensembl chr  X:47,582,408...47,586,789 		JBrowse link
G TNF tumor necrosis factor multiple interactions ISO rhapontin inhibits the reaction [Streptozocin results in increased expression of TNF mRNA] CTD PMID:32662907 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
trilobatin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAX BCL2 associated X, apoptosis regulator multiple interactions ISO trilobatin inhibits the reaction [Hydrogen Peroxide affects the localization of BAX protein] CTD PMID:30104959 NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798 		JBrowse link
G BCL2 BCL2 apoptosis regulator multiple interactions ISO trilobatin inhibits the reaction [Hydrogen Peroxide results in decreased expression of BCL2 protein] CTD PMID:30104959 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128 		JBrowse link
G CAT catalase multiple interactions ISO NFE2L2 protein affects the reaction [trilobatin inhibits the reaction [Isoflurane results in decreased activity of CAT protein]]; trilobatin inhibits the reaction [Isoflurane results in decreased activity of CAT protein] CTD PMID:32663520 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060 		JBrowse link
G ESRRA estrogen related receptor alpha multiple interactions ISO trilobatin inhibits the reaction [Hydrogen Peroxide results in decreased expression of ESRRA protein] CTD PMID:30104959 NCBI chr11:64,305,524...64,316,743
Ensembl chr11:64,305,497...64,316,743 		JBrowse link
G FOXO3 forkhead box O3 multiple interactions ISO trilobatin inhibits the reaction [Hydrogen Peroxide results in decreased expression of FOXO3 protein] CTD PMID:30104959 NCBI chr 6:108,559,825...108,684,774
Ensembl chr 6:108,559,835...108,684,774 		JBrowse link
G GPX1 glutathione peroxidase 1 multiple interactions ISO trilobatin inhibits the reaction [Hydrogen Peroxide results in decreased expression of GPX1 protein] CTD PMID:30104959 NCBI chr 3:49,357,176...49,358,353
Ensembl chr 3:49,357,174...49,358,605 		JBrowse link
G HMOX1 heme oxygenase 1 multiple interactions ISO trilobatin inhibits the reaction [Hydrogen Peroxide results in decreased expression of HMOX1 protein]
trilobatin promotes the reaction [Isoflurane results in increased expression of HMOX1 mRNA]; trilobatin promotes the reaction [Isoflurane results in increased expression of HMOX1 protein]		 CTD PMID:30104959 PMID:32663520 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214 		JBrowse link
G IDH2 isocitrate dehydrogenase (NADP(+)) 2 multiple interactions ISO trilobatin inhibits the reaction [Hydrogen Peroxide results in decreased activity of IDH2 protein]; trilobatin inhibits the reaction [Hydrogen Peroxide results in decreased expression of IDH2 protein] CTD PMID:30104959 NCBI chr15:90,083,045...90,102,468
Ensembl chr15:90,083,045...90,102,477 		JBrowse link
G IL1B interleukin 1 beta multiple interactions ISO trilobatin inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; trilobatin inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein] CTD PMID:25053100 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL6 interleukin 6 multiple interactions ISO trilobatin inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; trilobatin inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]; trilobatin inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein] CTD PMID:25053100 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G KEAP1 kelch like ECH associated protein 1 multiple interactions ISO trilobatin inhibits the reaction [Hydrogen Peroxide results in increased expression of KEAP1 protein] CTD PMID:30104959 NCBI chr19:10,486,125...10,503,356
Ensembl chr19:10,486,125...10,503,558 		JBrowse link
G MT-ATP6 mitochondrially encoded ATP synthase membrane subunit 6 multiple interactions ISO trilobatin inhibits the reaction [Hydrogen Peroxide results in decreased expression of ATP6 mRNA] CTD PMID:30104959 NCBI chr MT:8,527...9,207
Ensembl chr MT:8,527...9,207 		JBrowse link
G MT-CO1 mitochondrially encoded cytochrome c oxidase I multiple interactions ISO trilobatin inhibits the reaction [Hydrogen Peroxide results in decreased expression of COX1 mRNA] CTD PMID:30104959 NCBI chr MT:5,904...7,445
Ensembl chr MT:5,904...7,445 		JBrowse link
G MT-CYB mitochondrially encoded cytochrome b multiple interactions ISO trilobatin inhibits the reaction [Hydrogen Peroxide results in decreased expression of CYTB mRNA] CTD PMID:30104959 NCBI chr MT:14,747...15,887
Ensembl chr MT:14,747...15,887 		JBrowse link
G MT-ND2 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 2 multiple interactions ISO trilobatin inhibits the reaction [Hydrogen Peroxide results in decreased expression of ND2 mRNA] CTD PMID:30104959 NCBI chr MT:4,470...5,511
Ensembl chr MT:4,470...5,511 		JBrowse link
G MT-ND5 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 5 multiple interactions ISO trilobatin inhibits the reaction [Hydrogen Peroxide results in decreased expression of ND5 mRNA] CTD PMID:30104959 NCBI chr MT:12,337...14,148
Ensembl chr MT:12,337...14,148 		JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 multiple interactions ISO NFE2L2 protein affects the reaction [trilobatin inhibits the reaction [Isoflurane results in decreased activity of CAT protein]]; trilobatin promotes the reaction [Isoflurane results in increased expression of NFE2L2 protein]
trilobatin promotes the reaction [Hydrogen Peroxide affects the localization of NFE2L2 protein]		 CTD PMID:30104959 PMID:32663520 NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756 		JBrowse link
G NFKBIA NFKB inhibitor alpha multiple interactions ISO trilobatin inhibits the reaction [Lipopolysaccharides results in increased degradation of NFKBIA protein] CTD PMID:25053100 NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749 		JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 multiple interactions ISO trilobatin promotes the reaction [Isoflurane results in increased expression of NQO1 mRNA]; trilobatin promotes the reaction [Isoflurane results in increased expression of NQO1 protein]
trilobatin inhibits the reaction [Hydrogen Peroxide results in decreased expression of NQO1 protein]		 CTD PMID:30104959 PMID:32663520 NCBI chr16:69,709,401...69,726,560
Ensembl chr16:69,706,996...69,726,668 		JBrowse link
G PPARGC1A PPARG coactivator 1 alpha multiple interactions ISO trilobatin inhibits the reaction [Hydrogen Peroxide results in decreased expression of PPARGC1A protein] CTD PMID:30104959 NCBI chr 4:23,792,021...24,472,905
Ensembl chr 4:23,755,041...23,904,089 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit multiple interactions ISO trilobatin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of RELA protein] CTD PMID:25053100 NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090 		JBrowse link
G SIRT3 sirtuin 3 multiple interactions ISO trilobatin inhibits the reaction [Hydrogen Peroxide results in decreased expression of SIRT3 mRNA]; trilobatin inhibits the reaction [Hydrogen Peroxide results in decreased expression of SIRT3 protein] CTD PMID:30104959 NCBI chr11:215,030...236,931
Ensembl chr11:215,030...236,931 		JBrowse link
G SOD2 superoxide dismutase 2 multiple interactions ISO trilobatin inhibits the reaction [Hydrogen Peroxide results in decreased activity of SOD2 protein]; trilobatin inhibits the reaction [Hydrogen Peroxide results in increased acetylation of SOD2 protein] CTD PMID:30104959 NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529 		JBrowse link
G TNF tumor necrosis factor multiple interactions ISO trilobatin inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; trilobatin inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; trilobatin inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein] CTD PMID:25053100 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G UCP2 uncoupling protein 2 multiple interactions ISO trilobatin inhibits the reaction [Hydrogen Peroxide results in increased expression of UCP2 protein] CTD PMID:30104959 NCBI chr11:73,974,672...73,983,202
Ensembl chr11:73,974,672...73,982,843 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 26089
    role 26005
      biological role 25984
        biochemical role 25213
          metabolite 25143
            fundamental metabolite 15704
              glucose 2916
                D-glucose 2914
                  D-glucopyranose 1855
                    (+)-abscisic acid D-glucopyranosyl ester + 0
                    1-O-D-glucopyranosyl-D-mannitol + 0
                    2-(D-glucopyranosyloxy)-3-hydroxypropyl L-fucopyranoside 0
                    2-amino-2-deoxy-D-glucopyranose + 320
                    2-deoxy-2-fluoro-D-glucopyranose + 0
                    2-deoxy-D-glucopyranose 0
                    2-deoxy-D-glucose + 114
                    2-trans-abscisic acid D-glucosyl ester + 0
                    3-amino-3-deoxy-D-glucopyranose + 0
                    3-dehydro-D-glucose-6-phosphate 0
                    6-O-acetyl-D-glucose + 0
                    6-dehydro-D-glucose 0
                    6-deoxy-D-glucos-6-yl corynomycolate + 0
                    6-tuliposide A 0
                    6-tuliposide B 0
                    C80 D-glucose mono(keto-meromycolate) 0
                    D-Glcp-(1->2)-D-Galp 0
                    D-Glcp-(1->2)-beta-D-Galp 0
                    D-Glcp-(1<->1)-D-Xylp 0
                    D-glucopyranose 1-phosphate + 1
                    D-glucopyranose 3-sulfate 0
                    D-glucopyranose 6-phosphate + 8
                    D-glucopyranose 6-phosphate(2-) + 0
                    D-glucopyranose 6-sulfate 0
                    D-glucosyl group + 1
                    N-D-glucosylarylamine + 0
                    agrocinopine C 0
                    agrocinopine D 0
                    alpha-D-Galp-(1->2)-D-Glcp + 0
                    alpha-D-Galp-(1->3)-D-Glcp 0
                    alpha-D-GlcpNAc-(1->3)-D-Glcp 0
                    alpha-D-Xylp-(1->3)-D-Glcp 0
                    alpha-D-Xylp-(1->6)-D-Glcp + 0
                    alpha-D-glucose + 170
                    alpha-L-Fucp-(1->2)-D-Glcp + 0
                    alpha-L-Fucp-(1->3)-Glcp + 0
                    alpha-L-Fucp-(1->6)-D-Glcp + 0
                    beta-D-Galp-(1->2)-D-Glcp + 0
                    beta-D-Galp-(1->4)-beta-D-Galp-(1->3)-D-Glcp 0
                    beta-D-Galp3S-(1->4)-D-Glcp 0
                    beta-D-Xylp-(1->2)-D-Glcp 0
                    beta-D-Xylp-(1->3)-D-Glcp + 0
                    beta-D-Xylp-(1->4)-D-Glcp + 0
                    beta-D-Xylp-(1->6)-D-Glcp + 0
                    beta-D-glucose + 1710
                    glucose 6-monomycolate 0
                    glucose 6-monomycolate (C36) 0
                    glucose 6-monomycolate (C46) 0
                    glucose 6-monomycolate (C80) 0
                    glucose 6-monomycolate (C85) 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 26089
    subatomic particle 26064
      composite particle 26064
        hadron 26064
          baryon 26064
            nucleon 26016
              atomic nucleus 26064
                atom 26064
                  main group element atom 25891
                    p-block element atom 25891
                      carbon group element atom 25478
                        carbon atom 25437
                          organic molecular entity 25437
                            heteroorganic entity 24805
                              organochalcogen compound 24413
                                organooxygen compound 24093
                                  carbohydrates and carbohydrate derivatives 16793
                                    carbohydrate 16793
                                      monosaccharide 4984
                                        aldose 3338
                                          aldohexose 2963
                                            glucose 2916
                                              D-glucose 2914
                                                D-glucopyranose 1855
                                                  (+)-abscisic acid D-glucopyranosyl ester + 0
                                                  1-O-D-glucopyranosyl-D-mannitol + 0
                                                  2-(D-glucopyranosyloxy)-3-hydroxypropyl L-fucopyranoside 0
                                                  2-amino-2-deoxy-D-glucopyranose + 320
                                                  2-deoxy-2-fluoro-D-glucopyranose + 0
                                                  2-deoxy-D-glucopyranose 0
                                                  2-deoxy-D-glucose + 114
                                                  2-trans-abscisic acid D-glucosyl ester + 0
                                                  3-amino-3-deoxy-D-glucopyranose + 0
                                                  3-dehydro-D-glucose-6-phosphate 0
                                                  6-O-acetyl-D-glucose + 0
                                                  6-dehydro-D-glucose 0
                                                  6-deoxy-D-glucos-6-yl corynomycolate + 0
                                                  6-tuliposide A 0
                                                  6-tuliposide B 0
                                                  C80 D-glucose mono(keto-meromycolate) 0
                                                  D-Glcp-(1->2)-D-Galp 0
                                                  D-Glcp-(1->2)-beta-D-Galp 0
                                                  D-Glcp-(1<->1)-D-Xylp 0
                                                  D-glucopyranose 1-phosphate + 1
                                                  D-glucopyranose 3-sulfate 0
                                                  D-glucopyranose 6-phosphate + 8
                                                  D-glucopyranose 6-phosphate(2-) + 0
                                                  D-glucopyranose 6-sulfate 0
                                                  D-glucosyl group + 1
                                                  N-D-glucosylarylamine + 0
                                                  agrocinopine C 0
                                                  agrocinopine D 0
                                                  alpha-D-Galp-(1->2)-D-Glcp + 0
                                                  alpha-D-Galp-(1->3)-D-Glcp 0
                                                  alpha-D-GlcpNAc-(1->3)-D-Glcp 0
                                                  alpha-D-Xylp-(1->3)-D-Glcp 0
                                                  alpha-D-Xylp-(1->6)-D-Glcp + 0
                                                  alpha-D-glucose + 170
                                                  alpha-L-Fucp-(1->2)-D-Glcp + 0
                                                  alpha-L-Fucp-(1->3)-Glcp + 0
                                                  alpha-L-Fucp-(1->6)-D-Glcp + 0
                                                  beta-D-Galp-(1->2)-D-Glcp + 0
                                                  beta-D-Galp-(1->4)-beta-D-Galp-(1->3)-D-Glcp 0
                                                  beta-D-Galp3S-(1->4)-D-Glcp 0
                                                  beta-D-Xylp-(1->2)-D-Glcp 0
                                                  beta-D-Xylp-(1->3)-D-Glcp + 0
                                                  beta-D-Xylp-(1->4)-D-Glcp + 0
                                                  beta-D-Xylp-(1->6)-D-Glcp + 0
                                                  beta-D-glucose + 1710
                                                  glucose 6-monomycolate 0
                                                  glucose 6-monomycolate (C36) 0
                                                  glucose 6-monomycolate (C46) 0
                                                  glucose 6-monomycolate (C80) 0
                                                  glucose 6-monomycolate (C85) 0
paths to the root