SDC1 (syndecan 1) - Rat Genome Database

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Keyword

Gene: SDC1 (syndecan 1) Homo sapiens

Symbol:

SDC1

Name:

syndecan 1

Description:

The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein. [provided by RefSeq, Jul 2008]

Type:

protein-coding

RefSeq Status:

REVIEWED

Also known as:

CD138; CD138 antigen; heparan sulfate proteoglycan fibroblast growth factor receptor; OTTHUMP00000115942; SDC; SYND1; syndecan; syndecan proteoglycan 1; syndecan-1

Orthologs:

Mus musculus : Sdc1 (syndecan 1) MGI
Rattus norvegicus : Sdc1 (syndecan 1)

Latest Assembly:

Human Genome Assembly GRCh37

Position:

Map	Chr	Position	Strand	Source
Human Alternate Assembly CHM1_1	2	20,341,507 - 20,366,149	-	NCBI
Human Genome Assembly HuRef	2	20,158,155 - 20,182,491	-	NCBI
Human Genome Assembly GRCh37	2	20,400,558 - 20,425,194	-	NCBI
Human Genome Assembly Build 36	2	20,264,039 - 20,288,675	-	NCBI
Human Cytogenetic Map	2	p24.1		NCBI
Human Genome Assembly	2	20,322,187 - 20,346,555		NCBI