BIK (BCL2-interacting killer (apoptosis-inducing))

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Keyword

Gene: BIK (BCL2-interacting killer (apoptosis-inducing)) Homo sapiens

Symbol:

BIK

Name:

BCL2-interacting killer (apoptosis-inducing)

Description:

The protein encoded by this gene shares a critical BH3 domain with other death-promoting proteins, such as BID, BAK, BAD and BAX, that is required for its pro-apoptotic activity, and for interaction with anti-apoptotic members of the BCL2 family, and viral survival-promoting proteins. Since the activity of this protein is suppressed in the presence of survival-promoting proteins, it is suggested as a likely target for anti-apoptotic proteins. [provided by RefSeq, Sep 2011]

Type:

protein-coding

RefSeq Status:

REVIEWED

Also known as:

apoptosis inducer NBK; apoptosis-inducing NBK; bcl-2-interacting killer; BIP1; BP4; NBK; OTTHUMP00000198290

Orthologs:

Mus musculus : Bik (BCL2-interacting killer) MGI
Rattus norvegicus : Bik (BCL2-interacting killer (apoptosis-inducing))

Latest Assembly:

Human Genome Assembly GRCh37

Position:

Map	Chr	Position	Strand	Source
Human Alternate Assembly CHM1_1	22	27,423,712 - 27,442,677	+	NCBI
Human Genome Assembly HuRef	22	26,465,060 - 26,484,115	+	NCBI
Human Genome Assembly GRCh37	22	43,506,754 - 43,525,718	+	NCBI
Human Genome Assembly Build 36	22	41,836,701 - 41,855,662	+	NCBI
Human Cytogenetic Map	22	q13.31		NCBI
Human Genome Assembly	22	41,831,254 - 41,850,215		NCBI