Gene: HSD3B1 (hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1)  Homo sapiens
Symbol: HSD3B1
Name: hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
Description: ENCODES a protein that exhibits 3-beta-hydroxy-delta5-steroid dehydrogenase activity (ortholog); steroid delta-isomerase activity (ortholog); INVOLVED IN steroid biosynthetic process (ortholog); PARTICIPATES IN cortisol biosynthetic pathway; estradiol biosynthetic pathway; steroid hormone biosynthetic pathway; ASSOCIATED WITH Hypertension; Hyperprolactinemia (ortholog); FOUND IN mitochondrial inner membrane; mitochondrial intermembrane space; smooth endoplasmic reticulum membrane (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trichlorophenol
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1; 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type I; 3-beta-HSD I; 3-beta-hydroxy-5-ene steroid dehydrogenase; 3-beta-hydroxy-Delta(5)-steroid dehydrogenase; 3BETAHSD; delta-5-3-ketosteroid isomerase; HSD3B; HSDB3; HSDB3A; hydroxy-delta-5-steroid dehydrogenase, 3 beta-and steroid delta-isomerase 1; I; OTTHUMP00000014488; OTTHUMP00000234748; progesterone reductase; SDR11E1; short chain dehydrogenase/reductase family 11E, member 1; steroid Delta-isomerase; trophoblast antigen FDO161G
Orthologs: Mus musculus : Hsd3b6 (hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 6)  MGI
Rattus norvegicus : Hsd3b1 (hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1)
Related Pseudogenes: HSD3BP1   HSD3BP3   HSD3BP4   HSD3BP5  
Latest Assembly: Human Genome Assembly GRCh37
Position:
MapChrPositionStrandSource
Human Alternate Assembly CHM1_11120,121,424 - 120,129,278+NCBI
Human Genome Assembly HuRef1117,908,314 - 117,916,173+NCBI
Human Genome Assembly GRCh371120,049,826 - 120,057,681+NCBI
Human Genome Assembly Build 361119,851,349 - 119,859,204+NCBI
Human Cytogenetic Map1p13.1 NCBI
Human Genome Assembly1119,761,892 - 119,769,716 NCBI
Model

Launch Genome Browser (GBrowse) : build 36 (hg18) build 37 (hg19)

Annotation    (Toggle Detail/Summary View)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Human Genome Assembly GRCh37)

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
  
More on HSD3B1
Entrez Gene
Ensembl Gene
Genome Browser: (hg18) (hg19)
HGNC Report
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 1347893
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2013-03-06
Status: ACTIVE



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