Gene: IGF1 (insulin-like growth factor 1 (somatomedin C))  Homo sapiens

Symbol: IGF1
Name: insulin-like growth factor 1 (somatomedin C)
Description: The protein encoded by this gene is similar to insulin in function and structure and is a member of a family of proteins involved in mediating growth and development. The encoded protein is processed from a precursor, bound by a specific receptor, and secreted. Defects in this gene are a cause of insulin-like growth factor I deficiency. Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2009]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: IGF-I; IGF-IA; IGF-IB; IGF1A; IGFI; insulin-like growth factor 1; insulin-like growth factor I; insulin-like growth factor IA; insulin-like growth factor IB; mechano growth factor; MGF; OTTHUMP00000195080; OTTHUMP00000195081; OTTHUMP00000195082; OTTHUMP00000195083; OTTHUMP00000195084; somatomedin-C
Orthologs: Mus musculus : Igf1 (insulin-like growth factor 1)  MGI
Rattus norvegicus : Igf1 (insulin-like growth factor 1)
Is Marker For: QTLs:   BW58_H   BW104_H  
Latest Assembly: Human Genome Assembly GRCh37
Position:
MapChrPositionStrandSource
Human Alternate Assembly CHM1_112102,629,902 - 102,714,604-NCBI
Human Genome Assembly HuRef1299,849,028 - 99,933,911-NCBI
Human Genome Assembly GRCh3712102,789,645 - 102,874,378-NCBI
Human Genome Assembly Build 3612101,313,806 - 101,398,454-NCBI
Human Cytogenetic Map12q23.2 NCBI
Human Genome Assembly12101,292,143 - 101,376,791 NCBI
Model

Launch Genome Browser (GBrowse) : build 36 (hg18) build 37 (hg19)


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Human Genome Assembly GRCh37)

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on IGF1
Entrez Gene
Ensembl Gene
Genome Browser: (hg18) (hg19)
HGNC Report
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 70506
Created: 2002-05-02
Species: Homo sapiens
Last Modified: 2013-05-14
Status: ACTIVE