Gene: PPP3CA (protein phosphatase 3, catalytic subunit, alpha isozyme)  Homo sapiens
Symbol: PPP3CA
Name: protein phosphatase 3, catalytic subunit, alpha isozyme
Description: ENCODES a protein that exhibits calmodulin binding; calmodulin-dependent protein phosphatase activity; drug binding; INVOLVED IN cellular response to drug; protein dephosphorylation; response to calcium ion; PARTICIPATES IN interleukin-12 signaling pathway; Alzheimer disease pathway; amyotrophic lateral sclerosis disease pathway; ASSOCIATED WITH Brain Injuries (ortholog); Cardiomegaly (ortholog); Huntington Disease (ortholog); FOUND IN cytoplasm; nucleus; INTERACTS WITH 17beta-estradiol; 4-hydroxynon-2-enal; 5-fluorouracil
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: calcineurin A alpha; calmodulin-dependent calcineurin A subunit alpha isoform; CALN; CALNA; CALNA1; CAM-PRP catalytic subunit; CCN1; CNA1; OTTHUMP00000165327; OTTHUMP00000165328; OTTHUMP00000219549; OTTHUMP00000219550; OTTHUMP00000219551; PPP2B; protein phosphatase 2B, catalytic subunit, alpha isoform; protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform; protein phosphatase 3 (formerly 2b), catalytic subunit, alpha isoform (calcineurin a alpha); serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform
Orthologs: Mus musculus : Ppp3ca (protein phosphatase 3, catalytic subunit, alpha isoform)  MGI
Rattus norvegicus : Ppp3ca (protein phosphatase 3, catalytic subunit, alpha isozyme)
Latest Assembly: Human Genome Assembly GRCh37
Position:
MapChrPositionStrandSource
Human Alternate Assembly CHM1_14101,746,842 - 102,070,840-NCBI
Human Genome Assembly HuRef497,682,764 - 98,006,594-NCBI
Human Genome Assembly GRCh374101,944,587 - 102,268,628-NCBI
Human Genome Assembly Build 364102,163,610 - 102,487,376-NCBI
Human Cytogenetic Map4q24 NCBI
Human Genome Assembly4102,301,764 - 102,625,531 NCBI
Model

Launch Genome Browser (GBrowse) : build 36 (hg18) build 37 (hg19)

Annotation    (Toggle Detail/Summary View)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
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References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Human Genome Assembly GRCh37)

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
  
More on PPP3CA
Entrez Gene
Ensembl Gene
Genome Browser: (hg18) (hg19)
HGNC Report
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 730900
Created: 2003-12-10
Species: Homo sapiens
Last Modified: 2013-03-05
Status: ACTIVE



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