(4Z,7Z,10Z,13Z,15E,19Z)-17-hydroxydocosahexaenoic acid decreases expression ISO Alox5 (Mus musculus) 6480464 17-hydroxy-4 more ... CTD PMID:17056761 (4Z,7Z,10Z,13Z,15E,19Z)-17-hydroxydocosahexaenoic acid multiple interactions ISO Alox5 (Mus musculus) 6480464 17-hydroxy-4 more ... CTD PMID:34601004 (5Z,8Z,11Z,13E)-15-HETE multiple interactions EXP 6480464 [benoxaprofen results in decreased activity of ALOX5 protein] which results in increased abundance of 15-hydroxy-5 more ... CTD PMID:2849922 (S)-nicotine multiple interactions EXP 6480464 [RTKI cpd co-treated with AG 1879] inhibits the reaction [Nicotine results in increased expression of ALOX5 protein] more ... CTD PMID:14569062 and PMID:20061081 (S)-nicotine increases expression EXP 6480464 Nicotine results in increased expression of ALOX5 mRNA and Nicotine results in increased expression of ALOX5 protein CTD PMID:14569062 and PMID:20061081 1,2-dimethylhydrazine decreases expression ISO Alox5 (Mus musculus) 6480464 1 and 2-Dimethylhydrazine results in decreased expression of ALOX5 mRNA CTD PMID:22206623 1-O-palmitoyl-2-O-(5-oxovaleryl)-sn-glycero-3-phosphocholine increases expression EXP 6480464 1-palmitoyl-2-(5-oxovaleroyl)-sn-glycero-3-phosphorylcholine results in increased expression of ALOX5 mRNA CTD PMID:16386258 1-octadec-9-enoylglycero-3-phosphate multiple interactions EXP 6480464 ALOX5 protein promotes the reaction [lysophosphatidic acid results in increased abundance of Hydrogen Peroxide] more ... CTD PMID:10698703 17beta-estradiol decreases expression ISO Alox5 (Mus musculus) 6480464 Estradiol results in decreased expression of ALOX5 protein CTD PMID:17143502 17beta-estradiol multiple interactions ISO Alox5 (Rattus norvegicus) 6480464 [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of ALOX5 mRNA CTD PMID:32741896 17beta-estradiol increases expression ISO Alox5 (Mus musculus) 6480464 Estradiol results in increased expression of ALOX5 mRNA CTD PMID:19484750 17beta-estradiol 3-benzoate multiple interactions ISO Alox5 (Rattus norvegicus) 6480464 [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of ALOX5 mRNA CTD PMID:32741896 2,2',4,4'-Tetrabromodiphenyl ether decreases expression EXP 6480464 2 more ... CTD PMID:23146750 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO Alox5 (Rattus norvegicus) 6480464 Tetrachlorodibenzodioxin results in increased expression of ALOX5 mRNA and Tetrachlorodibenzodioxin results in increased expression of ALOX5 protein CTD PMID:28487374 more ... 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Alox5 (Rattus norvegicus) 6480464 Tetrachlorodibenzodioxin affects the expression of ALOX5 mRNA CTD PMID:34747641 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO Alox5 (Rattus norvegicus) 6480464 AHR mRNA promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of ALOX5 mRNA] CTD PMID:28487374 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO Alox5 (Mus musculus) 6480464 Tetrachlorodibenzodioxin results in increased expression of ALOX5 mRNA CTD PMID:28487374 2,6-di-tert-butyl-4-methylphenol affects localization ISO Alox5 (Mus musculus) 6480464 Butylated Hydroxytoluene affects the localization of ALOX5 protein CTD PMID:12376474 2,6-di-tert-butyl-4-methylphenol multiple interactions ISO Alox5 (Mus musculus) 6480464 celecoxib inhibits the reaction [Butylated Hydroxytoluene affects the localization of ALOX5 protein] CTD PMID:12376474 2-acetyl-1-alkyl-sn-glycero-3-phosphocholine increases expression EXP 6480464 Platelet Activating Factor results in increased expression of ALOX5 mRNA CTD PMID:16386258 2-acetyl-1-alkyl-sn-glycero-3-phosphocholine multiple interactions EXP 6480464 [sodium arsenite co-treated with Platelet Activating Factor co-treated with Arachidonic Acid] results in increased phosphorylation of and results in increased activity of ALOX5 protein and [zileuton results in decreased activity of ALOX5 protein] inhibits the reaction [Calcimycin results in increased abundance of Platelet Activating Factor] CTD PMID:10779545 and PMID:8387780 3,3',4,4',5-pentachlorobiphenyl increases expression ISO Alox5 (Rattus norvegicus) 6480464 3 more ... CTD PMID:34256052 3,3',4,4',5-pentachlorobiphenyl multiple interactions ISO Alox5 (Rattus norvegicus) 6480464 AHR gene mutant form inhibits the reaction [3 more ... CTD PMID:34256052 3-[3-(tert-butylsulfanyl)-1-(4-chlorobenzyl)-5-(propan-2-yl)-1H-indol-2-yl]-2,2-dimethylpropanoic acid decreases activity ISO Alox5 (Rattus norvegicus) 6480464 MK-886 results in decreased activity of ALOX5 protein CTD PMID:14726295 and PMID:9445378 3-[3-(tert-butylsulfanyl)-1-(4-chlorobenzyl)-5-(propan-2-yl)-1H-indol-2-yl]-2,2-dimethylpropanoic acid multiple interactions ISO Alox5 (Mus musculus) 6480464 EPHX2 gene mutant form promotes the reaction [MK-886 inhibits the reaction [Lipopolysaccharides results in increased expression of ALOX5 protein]] and MK-886 inhibits the reaction [Lipopolysaccharides results in increased expression of ALOX5 protein] CTD PMID:19896470 3-[3-(tert-butylsulfanyl)-1-(4-chlorobenzyl)-5-(propan-2-yl)-1H-indol-2-yl]-2,2-dimethylpropanoic acid multiple interactions EXP 6480464 MK-886 inhibits the reaction [ALOX5 protein results in increased metabolism of Hydroxyeicosatetraenoic Acids metabolite] and MK-886 inhibits the reaction [Nicotine results in increased expression of ALOX5 protein] CTD PMID:11861792 and PMID:20061081 3-\{1-[3-(dimethylamino)propyl]-1H-indol-3-yl\}-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione multiple interactions EXP 6480464 bisindolylmaleimide I inhibits the reaction [Calcimycin results in increased phosphorylation of and results in increased activity of ALOX5 protein] CTD PMID:10779545 4-hydroxycyclophosphamide multiple interactions ISO Alox5 (Rattus norvegicus) 6480464 [afimoxifene co-treated with 4-hydroxycyclophosphamide] affects the expression of ALOX5 mRNA CTD PMID:25833159 4-hydroxynon-2-enal multiple interactions ISO Alox5 (Mus musculus) 6480464 ALOX5 mutant form inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of MMP9 protein] CTD PMID:19837106 acetamide increases expression ISO Alox5 (Rattus norvegicus) 6480464 acetamide results in increased expression of ALOX5 mRNA CTD PMID:31881176 acrolein increases expression ISO Alox5 (Mus musculus) 6480464 Acrolein results in increased expression of ALOX5 mRNA and Acrolein results in increased expression of ALOX5 protein CTD PMID:20153347 acrolein multiple interactions ISO Alox5 (Mus musculus) 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Acrolein results in increased expression of ALOX5 protein] and RTKI cpd inhibits the reaction [Acrolein results in increased expression of ALOX5 protein] CTD PMID:20153347 acrolein increases activity ISO Alox5 (Mus musculus) 6480464 Acrolein results in increased activity of ALOX5 protein CTD PMID:20153347 acrylamide decreases expression ISO Alox5 (Rattus norvegicus) 6480464 Acrylamide results in decreased expression of ALOX5 mRNA CTD PMID:28959563 afimoxifene multiple interactions ISO Alox5 (Rattus norvegicus) 6480464 [afimoxifene co-treated with 4-hydroxycyclophosphamide] affects the expression of ALOX5 mRNA CTD PMID:25833159 aflatoxin B1 increases expression EXP 6480464 Aflatoxin B1 results in increased expression of ALOX5 mRNA CTD PMID:22100608 aflatoxin B1 increases expression ISO Alox5 (Rattus norvegicus) 6480464 Aflatoxin B1 results in increased expression of ALOX5 mRNA CTD PMID:33354967 aldehydo-D-glucose multiple interactions ISO Alox5 (Rattus norvegicus) 6480464 [Oxygen deficiency co-treated with Glucose deficiency] affects the localization of ALOX5 protein more ... CTD PMID:18951527 aldehydo-D-glucose increases expression EXP 6480464 Glucose results in increased expression of ALOX5 mRNA CTD PMID:31655124 all-trans-retinoic acid increases expression EXP 6480464 Tretinoin results in increased expression of ALOX5 mRNA CTD PMID:16129123 and PMID:33167477 aluminium atom increases expression ISO Alox5 (Rattus norvegicus) 6480464 Aluminum results in increased expression of ALOX5 mRNA and Aluminum results in increased expression of ALOX5 protein CTD PMID:27368151 aluminium atom multiple interactions ISO Alox5 (Rattus norvegicus) 6480464 caffeic acid inhibits the reaction [Aluminum results in increased expression of ALOX5 mRNA] and caffeic acid inhibits the reaction [Aluminum results in increased expression of ALOX5 protein] CTD PMID:27368151 aluminium(0) increases expression ISO Alox5 (Rattus norvegicus) 6480464 Aluminum results in increased expression of ALOX5 mRNA and Aluminum results in increased expression of ALOX5 protein CTD PMID:27368151 aluminium(0) multiple interactions ISO Alox5 (Rattus norvegicus) 6480464 caffeic acid inhibits the reaction [Aluminum results in increased expression of ALOX5 mRNA] and caffeic acid inhibits the reaction [Aluminum results in increased expression of ALOX5 protein] CTD PMID:27368151 ammonium chloride affects expression ISO Alox5 (Rattus norvegicus) 6480464 Ammonium Chloride affects the expression of ALOX5 mRNA CTD PMID:16483693 amphotericin B decreases expression EXP 6480464 Amphotericin B analog results in decreased expression of ALOX5 mRNA CTD PMID:28534445 anthra[1,9-cd]pyrazol-6(2H)-one decreases expression EXP 6480464 pyrazolanthrone results in decreased expression of ALOX5 protein CTD PMID:23539630 antirheumatic drug decreases expression EXP 6480464 Antirheumatic Agents results in decreased expression of ALOX5 mRNA CTD PMID:24449571 arachidonic acid multiple interactions EXP 6480464 [sodium arsenite co-treated with Platelet Activating Factor co-treated with Arachidonic Acid] results in increased phosphorylation of and results in increased activity of ALOX5 protein more ... CTD PMID:10779545 more ... arachidonic acid increases metabolic processing EXP 6480464 ALOX5 protein results in increased metabolism of Arachidonic Acid CTD PMID:18295198 aristolochic acid A increases expression ISO Alox5 (Rattus norvegicus) 6480464 aristolochic acid I results in increased expression of ALOX5 mRNA CTD PMID:36863539 arsane affects expression EXP 6480464 Arsenic affects the expression of ALOX5 mRNA CTD PMID:18414638 arsenic atom affects expression EXP 6480464 Arsenic affects the expression of ALOX5 mRNA CTD PMID:18414638 baicalin multiple interactions ISO Alox5 (Rattus norvegicus) 6480464 baicalin inhibits the reaction [Hydrogen Peroxide affects the localization of and results in increased activity of ALOX5 protein] CTD PMID:20139896 benoxaprofen decreases activity EXP 6480464 benoxaprofen results in decreased activity of ALOX5 protein CTD PMID:2849922 and PMID:3020588 benoxaprofen decreases activity ISO Alox5 (Rattus norvegicus) 6480464 benoxaprofen results in decreased activity of ALOX5 protein CTD PMID:2724698 and PMID:3928952 benoxaprofen multiple interactions EXP 6480464 [benoxaprofen results in decreased activity of ALOX5 protein] which results in decreased chemical synthesis of Leukotriene B4 more ... CTD PMID:2849922 benzene affects response to substance EXP 6480464 ALOX5 gene SNP affects the susceptibility to Benzene CTD PMID:21540635 benzene increases expression EXP 6480464 Benzene results in increased expression of ALOX5 mRNA CTD PMID:33064461 benzo[a]pyrene multiple interactions EXP 6480464 Benzo(a)pyrene promotes the reaction [Calcitriol results in increased expression of ALOX5 mRNA] CTD PMID:19244278 benzo[a]pyrene increases expression EXP 6480464 Benzo(a)pyrene results in increased expression of ALOX5 mRNA CTD PMID:32234424 benzo[a]pyrene increases methylation EXP 6480464 Benzo(a)pyrene results in increased methylation of ALOX5 3' UTR and Benzo(a)pyrene results in increased methylation of ALOX5 promoter CTD PMID:27901495 benzo[a]pyrene decreases methylation EXP 6480464 Benzo(a)pyrene results in decreased methylation of ALOX5 exon CTD PMID:27901495 benzo[a]pyrene increases expression ISO Alox5 (Mus musculus) 6480464 Benzo(a)pyrene results in increased expression of ALOX5 mRNA CTD PMID:19770486 and PMID:23735875 benzo[a]pyrene decreases expression ISO Alox5 (Mus musculus) 6480464 Benzo(a)pyrene results in decreased expression of ALOX5 mRNA CTD PMID:22228805 benzo[a]pyrene multiple interactions ISO Alox5 (Mus musculus) 6480464 Benzo(a)pyrene promotes the reaction [AHR protein binds to ALOX5 promoter] CTD PMID:19654925 benzo[b]fluoranthene increases expression ISO Alox5 (Mus musculus) 6480464 benzo(b)fluoranthene results in increased expression of ALOX5 mRNA CTD PMID:26377693 beta-D-glucosamine 6-sulfate multiple interactions EXP 6480464 glucosamine 6-O-sulfate inhibits the reaction [Lipopolysaccharides results in increased expression of ALOX5 mRNA] CTD PMID:21877189 beta-naphthoflavone increases expression EXP 6480464 beta-Naphthoflavone results in increased expression of ALOX5 mRNA CTD PMID:19737606 bisphenol A increases methylation ISO Alox5 (Rattus norvegicus) 6480464 bisphenol A results in increased methylation of ALOX5 gene CTD PMID:28505145 bisphenol A increases expression ISO Alox5 (Mus musculus) 6480464 bisphenol A results in increased expression of ALOX5 mRNA CTD PMID:32156529 bisphenol A increases expression ISO Alox5 (Rattus norvegicus) 6480464 bisphenol A results in increased expression of ALOX5 mRNA CTD PMID:30816183 and PMID:34973380 Bromoenol lactone multiple interactions EXP 6480464 1-oleoyl-2-acetoyl-sn-glycerol inhibits the reaction [6-(bromomethylene)tetrahydro-3-(1-naphthaleneyl)-2H-pyran-2-one inhibits the reaction [Calcimycin results in increased activity of and results in increased localization of ALOX5 protein]] and 6-(bromomethylene)tetrahydro-3-(1-naphthaleneyl)-2H-pyran-2-one inhibits the reaction [Calcimycin results in increased activity of and results in increased localization of ALOX5 protein] CTD PMID:18218859 butan-1-ol multiple interactions EXP 6480464 1-Butanol inhibits the reaction [Calcimycin results in increased activity of and results in increased localization of ALOX5 protein] more ... CTD PMID:18218859 butanal increases expression EXP 6480464 butyraldehyde results in increased expression of ALOX5 mRNA CTD PMID:26079696 butyric acid increases expression EXP 6480464 Butyric Acid results in increased expression of ALOX5 mRNA CTD PMID:34581912 Calcimycin multiple interactions EXP 6480464 1-Butanol inhibits the reaction [Calcimycin results in increased activity of and results in increased localization of ALOX5 protein] more ... CTD PMID:10779545 more ... Calcimycin increases activity EXP 6480464 Calcimycin results in increased activity of ALOX5 protein CTD PMID:11698504 and PMID:18475477 Calcimycin increases expression ISO Alox5 (Rattus norvegicus) 6480464 Calcimycin results in increased expression of ALOX5 mRNA and Calcimycin results in increased expression of ALOX5 protein CTD PMID:18083043 Calcimycin multiple interactions ISO Alox5 (Rattus norvegicus) 6480464 [[A 78773 co-treated with Calcimycin] results in decreased activity of ALOX5 protein] which results in decreased abundance of Leukotriene B4 more ... CTD PMID:11529688 more ... calcitriol increases activity EXP 6480464 Calcitriol analog results in increased activity of ALOX5 protein CTD PMID:10799658 calcitriol increases expression EXP 6480464 Calcitriol results in increased expression of ALOX5 mRNA CTD PMID:16002434 more ... calcitriol multiple interactions EXP 6480464 Benzo(a)pyrene promotes the reaction [Calcitriol results in increased expression of ALOX5 mRNA] CTD PMID:19244278 calcium atom multiple interactions EXP 6480464 Calcium promotes the reaction [L 708714 binds to ALOX5 protein] CTD PMID:7577949 calcium(0) multiple interactions EXP 6480464 Calcium promotes the reaction [L 708714 binds to ALOX5 protein] CTD PMID:7577949 cantharidin decreases expression ISO Alox5 (Mus musculus) 6480464 Cantharidin results in decreased expression of ALOX5 mRNA CTD PMID:36907384 capsaicin multiple interactions ISO Alox5 (Rattus norvegicus) 6480464 [Capsaicin co-treated with Curcumin] results in decreased activity of ALOX5 protein CTD PMID:16956363 capsaicin decreases activity ISO Alox5 (Rattus norvegicus) 6480464 Capsaicin results in decreased activity of ALOX5 protein CTD PMID:16956363 carbon nanotube decreases expression ISO Alox5 (Mus musculus) 6480464 Nanotubes and Carbon results in decreased expression of ALOX5 mRNA CTD PMID:25554681 celecoxib multiple interactions ISO Alox5 (Mus musculus) 6480464 Celecoxib inhibits the reaction [Butylated Hydroxytoluene affects the localization of ALOX5 protein] CTD PMID:12376474 cetirizine decreases activity EXP 6480464 Cetirizine analog results in decreased activity of ALOX5 protein CTD PMID:15482930 CGP 52608 multiple interactions EXP 6480464 CGP 52608 promotes the reaction [RORA protein binds to ALOX5 gene] CTD PMID:28238834 choline multiple interactions ISO Alox5 (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ALOX5 mRNA CTD PMID:20938992 chromium(6+) affects expression ISO Alox5 (Mus musculus) 6480464 chromium hexavalent ion affects the expression of ALOX5 mRNA CTD PMID:28472532 cis-caffeic acid multiple interactions ISO Alox5 (Rattus norvegicus) 6480464 caffeic acid inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] affects the localization of ALOX5 protein] more ... CTD PMID:18951527 and PMID:27368151 cis-caffeic acid multiple interactions ISO Alox5 (Mus musculus) 6480464 caffeic acid inhibits the reaction [aluminum chloride results in increased expression of ALOX5 mRNA] and caffeic acid inhibits the reaction [aluminum chloride results in increased expression of ALOX5 protein] CTD PMID:18482095 cisplatin multiple interactions EXP 6480464 [Cisplatin co-treated with jinfukang] results in increased expression of ALOX5 mRNA CTD PMID:27392435 cisplatin increases expression EXP 6480464 Cisplatin results in increased expression of ALOX5 mRNA CTD PMID:27392435 and PMID:27594783 coumarin increases expression ISO Alox5 (Rattus norvegicus) 6480464 coumarin results in increased expression of ALOX5 mRNA CTD PMID:18480146 Cuprizon decreases expression EXP 6480464 Cuprizone results in decreased expression of ALOX5 protein CTD PMID:34122009 curcumin decreases activity ISO Alox5 (Rattus norvegicus) 6480464 Curcumin results in decreased activity of ALOX5 protein CTD PMID:16956363 curcumin multiple interactions ISO Alox5 (Rattus norvegicus) 6480464 [Capsaicin co-treated with Curcumin] results in decreased activity of ALOX5 protein CTD PMID:16956363 D-glucitol multiple interactions EXP 6480464 [Sorbitol co-treated with Calcimycin co-treated with Arachidonic Acid] affects the localization of ALOX5 protein more ... CTD PMID:10779545 and PMID:11698504 D-glucose multiple interactions ISO Alox5 (Rattus norvegicus) 6480464 [Oxygen deficiency co-treated with Glucose deficiency] affects the localization of ALOX5 protein more ... CTD PMID:18951527 D-glucose increases expression EXP 6480464 Glucose results in increased expression of ALOX5 mRNA CTD PMID:31655124 dexamethasone multiple interactions ISO Alox5 (Rattus norvegicus) 6480464 Dexamethasone inhibits the reaction [[CCL5 protein co-treated with Calcimycin] results in increased expression of ALOX5 protein] CTD PMID:18083043 dextran sulfate multiple interactions ISO Alox5 (Mus musculus) 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of ALOX5 mRNA CTD PMID:29950665 dioxygen multiple interactions ISO Alox5 (Rattus norvegicus) 6480464 [Oxygen deficiency co-treated with Glucose deficiency] affects the localization of ALOX5 protein more ... CTD PMID:18951527 dioxygen increases expression EXP 6480464 Oxygen deficiency results in increased expression of ALOX5 mRNA CTD PMID:26516004 dithiol decreases activity ISO Alox5 (Rattus norvegicus) 6480464 dithiol results in decreased activity of ALOX5 protein CTD PMID:3928952 docebenone decreases activity EXP 6480464 2 more ... CTD PMID:2724698 docebenone decreases activity ISO Alox5 (Mus musculus) 6480464 2 more ... CTD PMID:25432964 and PMID:7812673 docebenone decreases activity ISO Alox5 (Rattus norvegicus) 6480464 2 more ... CTD PMID:2724698 dorsomorphin multiple interactions EXP 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ALOX5 mRNA CTD PMID:27188386 doxorubicin multiple interactions EXP 6480464 TP53 gene mutant form inhibits the reaction [Doxorubicin results in increased expression of ALOX5 mRNA] and TP53 protein promotes the reaction [Doxorubicin results in increased expression of ALOX5 mRNA] CTD PMID:30258081 doxorubicin increases expression EXP 6480464 Doxorubicin results in increased expression of ALOX5 mRNA CTD PMID:30258081 ebselen decreases activity EXP 6480464 ebselen results in decreased activity of ALOX5 protein CTD PMID:7590103 edaravone multiple interactions ISO Alox5 (Rattus norvegicus) 6480464 Edaravone inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] affects the localization of ALOX5 protein] and Edaravone inhibits the reaction [Hydrogen Peroxide affects the localization of ALOX5 protein] CTD PMID:18951527 elemental selenium multiple interactions ISO Alox5 (Rattus norvegicus) 6480464 [Vitamin E co-treated with Selenium] results in decreased expression of ALOX5 mRNA and [Vitamin E co-treated with Selenium] results in decreased expression of ALOX5 protein CTD PMID:22223226 endosulfan increases expression EXP 6480464 Endosulfan results in increased expression of ALOX5 mRNA CTD PMID:26615145 endosulfan decreases expression ISO Alox5 (Rattus norvegicus) 6480464 Endosulfan results in decreased expression of ALOX5 mRNA CTD PMID:29391264 entinostat increases expression EXP 6480464 entinostat results in increased expression of ALOX5 mRNA CTD PMID:27188386 ethoxyquin decreases activity ISO Alox5 (Rattus norvegicus) 6480464 Ethoxyquin results in decreased activity of ALOX5 protein CTD PMID:3928952 flavonoids increases expression ISO Alox5 (Rattus norvegicus) 6480464 Flavonoids results in increased expression of ALOX5 mRNA CTD PMID:18035473 folic acid multiple interactions ISO Alox5 (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ALOX5 mRNA CTD PMID:20938992 fructose increases expression EXP 6480464 Fructose results in increased expression of ALOX5 mRNA CTD PMID:31655124 furan increases expression ISO Alox5 (Rattus norvegicus) 6480464 furan results in increased expression of ALOX5 mRNA CTD PMID:27387713 glucose multiple interactions ISO Alox5 (Rattus norvegicus) 6480464 [Oxygen deficiency co-treated with Glucose deficiency] affects the localization of ALOX5 protein more ... CTD PMID:18951527 glucose increases expression EXP 6480464 Glucose results in increased expression of ALOX5 mRNA CTD PMID:31655124 histamine multiple interactions EXP 6480464 ALOX5 protein results in increased susceptibility to [Histamine results in increased abundance of Leukotriene B4] and zileuton inhibits the reaction [ALOX5 protein results in increased susceptibility to [Histamine results in increased abundance of Leukotriene B4]] CTD PMID:9609743 hydrogen peroxide multiple interactions EXP 6480464 [Hydrogen Peroxide results in increased activity of ALOX5 protein] which results in increased chemical synthesis of Leukotriene B4 more ... CTD PMID:10491155 and PMID:10698703 hydrogen peroxide decreases activity ISO Alox5 (Rattus norvegicus) 6480464 Hydrogen Peroxide results in decreased activity of ALOX5 protein CTD PMID:12388339 hydrogen peroxide affects localization ISO Alox5 (Rattus norvegicus) 6480464 Hydrogen Peroxide affects the localization of ALOX5 protein CTD PMID:18951527 hydrogen peroxide multiple interactions ISO Alox5 (Rattus norvegicus) 6480464 baicalin inhibits the reaction [Hydrogen Peroxide affects the localization of and results in increased activity of ALOX5 protein] more ... CTD PMID:18951527 and PMID:20139896 hydrogen peroxide increases activity EXP 6480464 Hydrogen Peroxide results in increased activity of ALOX5 protein CTD PMID:10491155 hydroxamic acid decreases activity ISO Alox5 (Rattus norvegicus) 6480464 Hydroxamic Acids analog results in decreased activity of ALOX5 protein CTD PMID:7922131 hydroxyurea multiple interactions EXP 6480464 Hydroxyurea inhibits the reaction [L 708714 binds to ALOX5 protein] CTD PMID:7577949 indometacin multiple interactions ISO Alox5 (Rattus norvegicus) 6480464 [tepoxalin results in decreased activity of ALOX5 protein] inhibits the reaction [Indomethacin results in increased abundance of Leukotriene B4] more ... CTD PMID:35446470 and PMID:9223651 indometacin decreases activity ISO Alox5 (Rattus norvegicus) 6480464 Indomethacin results in decreased activity of ALOX5 protein CTD PMID:3928952 kaempferol multiple interactions EXP 6480464 kaempferol inhibits the reaction [ALOX5 protein results in increased chemical synthesis of Leukotriene B4] CTD PMID:18096136 L-methionine multiple interactions ISO Alox5 (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ALOX5 mRNA CTD PMID:20938992 leukotriene A4 increases chemical synthesis EXP 6480464 ALOX5 protein results in increased chemical synthesis of Leukotriene A4 CTD PMID:18295198 leukotriene B4 multiple interactions EXP 6480464 [benoxaprofen results in decreased activity of ALOX5 protein] which results in decreased chemical synthesis of Leukotriene B4 more ... CTD PMID:10491155 more ... leukotriene B4 increases chemical synthesis EXP 6480464 ALOX5 protein results in increased chemical synthesis of Leukotriene B4 CTD PMID:18096136 leukotriene B4 multiple interactions ISO Alox5 (Rattus norvegicus) 6480464 [[A 78773 co-treated with Calcimycin] results in decreased activity of ALOX5 protein] which results in decreased abundance of Leukotriene B4 more ... CTD PMID:10694244 more ... leukotriene B4 multiple interactions ISO Alox5 (Mus musculus) 6480464 [zileuton results in decreased activity of ALOX5 protein] which results in decreased abundance of Leukotriene B4 more ... CTD PMID:12794006 and PMID:9593866 leukotriene B4 increases secretion EXP 6480464 ALOX5 protein results in increased secretion of Leukotriene B4 CTD PMID:11325678 leukotriene C4 multiple interactions EXP 6480464 [zileuton results in decreased activity of ALOX5 protein] inhibits the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased abundance of Leukotriene C4] and [zileuton results in decreased activity of ALOX5 protein] which results in decreased abundance of Leukotriene C4 CTD PMID:10764316 and PMID:9495842 leukotriene C4 multiple interactions ISO Alox5 (Rattus norvegicus) 6480464 [Calcimycin results in increased activity of and results in increased localization of ALOX5 protein] which results in increased abundance of Leukotriene C4 CTD PMID:9445378 leukotriene C4 multiple interactions ISO Alox5 (Mus musculus) 6480464 ALOX5 protein promotes the reaction [Ovalbumin results in increased abundance of Leukotriene C4] and zileuton inhibits the reaction [ALOX5 protein promotes the reaction [Ovalbumin results in increased abundance of Leukotriene C4]] CTD PMID:12794006 leukotriene D4 increases abundance EXP 6480464 ALOX5 protein results in increased abundance of Leukotriene D4 CTD PMID:12629151 leukotriene D4 multiple interactions ISO Alox5 (Mus musculus) 6480464 ALOX5 protein promotes the reaction [Ovalbumin results in increased abundance of Leukotriene D4] and zileuton inhibits the reaction [ALOX5 protein promotes the reaction [Ovalbumin results in increased abundance of Leukotriene D4]] CTD PMID:12794006 leukotriene D4 multiple interactions EXP 6480464 [zileuton results in decreased activity of ALOX5 protein] which results in decreased abundance of Leukotriene D4 CTD PMID:10764316 leukotriene E4 multiple interactions ISO Alox5 (Mus musculus) 6480464 ALOX5 protein promotes the reaction [Ovalbumin results in increased abundance of Leukotriene E4] and zileuton inhibits the reaction [ALOX5 protein promotes the reaction [Ovalbumin results in increased abundance of Leukotriene E4]] CTD PMID:12794006 leukotriene E4 multiple interactions EXP 6480464 [zileuton results in decreased activity of ALOX5 protein] which results in decreased abundance of Leukotriene E4 CTD PMID:10764316 and PMID:8621850 lipopolysaccharide multiple interactions EXP 6480464 [S-(1 more ... CTD PMID:10779545 more ... lipopolysaccharide increases expression EXP 6480464 Lipopolysaccharides results in increased expression of ALOX5 mRNA CTD PMID:21877189 lipopolysaccharide increases expression ISO Alox5 (Mus musculus) 6480464 Lipopolysaccharides results in increased expression of ALOX5 mRNA and Lipopolysaccharides results in increased expression of ALOX5 protein CTD PMID:19896470 and PMID:20453108 lipopolysaccharide multiple interactions ISO Alox5 (Mus musculus) 6480464 EPHX2 gene mutant form inhibits the reaction [Lipopolysaccharides results in increased expression of ALOX5 protein] more ... CTD PMID:19896470 lipoxin A4 multiple interactions ISO Alox5 (Rattus norvegicus) 6480464 zileuton inhibits the reaction [ALOX5 protein affects the abundance of lipoxin A4] CTD PMID:15326064 lipoxin A4 affects abundance ISO Alox5 (Rattus norvegicus) 6480464 ALOX5 protein affects the abundance of lipoxin A4 CTD PMID:15326064 lonapalene decreases activity EXP 6480464 RS 43179 results in decreased activity of ALOX5 protein CTD PMID:2849922 lonapalene multiple interactions EXP 6480464 [RS 43179 results in decreased activity of ALOX5 protein] which results in decreased chemical synthesis of Leukotriene B4 more ... CTD PMID:2849922 loratadine decreases activity EXP 6480464 Loratadine analog results in decreased activity of ALOX5 protein CTD PMID:15482930 losartan decreases expression ISO Alox5 (Rattus norvegicus) 6480464 Losartan results in decreased expression of ALOX5 protein CTD PMID:21377515 lupeol multiple interactions ISO Alox5 (Rattus norvegicus) 6480464 lupeol inhibits the reaction [COL2A1 results in increased activity of ALOX5 protein] CTD PMID:35446470 luteolin multiple interactions EXP 6480464 Luteolin inhibits the reaction [ALOX5 protein results in increased chemical synthesis of Leukotriene B4] CTD PMID:18096136 masoprocol decreases activity EXP 6480464 Masoprocol results in decreased activity of ALOX5 protein CTD PMID:10698703 more ... masoprocol affects response to substance EXP 6480464 ALOX5 protein affects the susceptibility to Masoprocol CTD PMID:19503098 masoprocol decreases activity ISO Alox5 (Rattus norvegicus) 6480464 Masoprocol results in decreased activity of ALOX5 protein CTD PMID:2724698 and PMID:3928952 masoprocol multiple interactions ISO Alox5 (Rattus norvegicus) 6480464 Masoprocol inhibits the reaction [[CCL5 protein co-treated with Calcimycin] results in increased expression of ALOX5 mRNA] and Masoprocol inhibits the reaction [[CCL5 protein co-treated with Calcimycin] results in increased expression of ALOX5 protein] CTD PMID:18083043 masoprocol multiple interactions EXP 6480464 [Masoprocol results in decreased activity of ALOX5 protein] which results in decreased chemical synthesis of Leukotriene B4 more ... CTD PMID:10698703 and PMID:2849922 meclofenamic acid decreases activity EXP 6480464 Meclofenamic Acid results in decreased activity of ALOX5 protein CTD PMID:3020588 melittin increases activity EXP 6480464 Melitten results in increased activity of ALOX5 protein CTD PMID:18475477 methotrexate affects response to substance EXP 6480464 ALOX5 protein affects the susceptibility to Methotrexate CTD PMID:16217747 methylmercury chloride decreases expression EXP 6480464 methylmercuric chloride results in decreased expression of ALOX5 mRNA CTD PMID:28001369 microcystin-LR increases expression ISO Alox5 (Mus musculus) 6480464 cyanoginosin LR results in increased expression of ALOX5 mRNA CTD PMID:37342990 miquelianin multiple interactions EXP 6480464 quercetin 3-O-glucuronide inhibits the reaction [ALOX5 protein results in increased chemical synthesis of Leukotriene B4] CTD PMID:18096136 montelukast affects response to substance EXP 6480464 ALOX5 gene SNP affects the susceptibility to montelukast CTD PMID:16293801 N-formyl-L-methionyl-L-leucyl-L-phenylalanine multiple interactions EXP 6480464 [zileuton results in decreased activity of ALOX5 protein] inhibits the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased abundance of Leukotriene C4] more ... CTD PMID:10779545 more ... N-nitrosodiethylamine increases expression ISO Alox5 (Mus musculus) 6480464 Diethylnitrosamine results in increased expression of ALOX5 mRNA CTD PMID:24535843 nickel atom increases expression EXP 6480464 Nickel results in increased expression of ALOX5 mRNA CTD PMID:24768652 and PMID:25583101 niclosamide increases expression ISO Alox5 (Mus musculus) 6480464 Niclosamide results in increased expression of ALOX5 mRNA CTD PMID:30258081 niclosamide decreases response to substance EXP 6480464 ALOX5 protein results in decreased susceptibility to Niclosamide CTD PMID:30258081 niclosamide increases expression EXP 6480464 Niclosamide results in increased expression of ALOX5 mRNA CTD PMID:30258081 niclosamide multiple interactions EXP 6480464 TP53 gene mutant form inhibits the reaction [Niclosamide results in increased expression of ALOX5 mRNA] and TP53 protein mutant form inhibits the reaction [Niclosamide results in increased expression of ALOX5 mRNA] CTD PMID:30258081 nicotine multiple interactions EXP 6480464 [RTKI cpd co-treated with AG 1879] inhibits the reaction [Nicotine results in increased expression of ALOX5 protein] more ... CTD PMID:14569062 and PMID:20061081 nicotine increases expression EXP 6480464 Nicotine results in increased expression of ALOX5 mRNA and Nicotine results in increased expression of ALOX5 protein CTD PMID:14569062 and PMID:20061081 nitric oxide multiple interactions ISO Alox5 (Rattus norvegicus) 6480464 Nitric Oxide promotes the reaction [Reactive Oxygen Species results in decreased activity of ALOX5 protein] CTD PMID:12388339 O-methyleugenol increases expression EXP 6480464 methyleugenol results in increased expression of ALOX5 mRNA CTD PMID:32234424 ochratoxin A decreases expression EXP 6480464 ochratoxin A results in decreased expression of ALOX5 mRNA CTD PMID:26505656 ochratoxin A affects expression EXP 6480464 ochratoxin A affects the expression of ALOX5 mRNA CTD PMID:26505656 oxaliplatin increases expression ISO Alox5 (Rattus norvegicus) 6480464 oxaliplatin results in increased expression of ALOX5 mRNA CTD PMID:25729387 ozone multiple interactions EXP 6480464 [Air Pollutants results in increased abundance of Ozone] which affects the expression of ALOX5 mRNA CTD PMID:35430440 paracetamol affects expression ISO Alox5 (Mus musculus) 6480464 Acetaminophen affects the expression of ALOX5 mRNA CTD PMID:17562736 paraquat increases expression ISO Alox5 (Mus musculus) 6480464 Paraquat results in increased expression of ALOX5 mRNA CTD PMID:28012437 paraquat decreases expression ISO Alox5 (Rattus norvegicus) 6480464 Paraquat results in decreased expression of ALOX5 mRNA CTD PMID:32680482 pentanal increases expression EXP 6480464 pentanal results in increased expression of ALOX5 mRNA CTD PMID:26079696 peroxynitrous acid decreases activity ISO Alox5 (Rattus norvegicus) 6480464 Peroxynitrous Acid results in decreased activity of ALOX5 protein CTD PMID:12388339 peroxynitrous acid multiple interactions ISO Alox5 (Rattus norvegicus) 6480464 Peroxynitrous Acid results in increased nitrosation of and affects the expression of ALOX5 protein and zileuton inhibits the reaction [Peroxynitrous Acid results in increased nitrosation of ALOX5 protein] CTD PMID:11561080 PhIP decreases expression EXP 6480464 2-amino-1-methyl-6-phenylimidazo(4 and 5-b)pyridine results in decreased expression of ALOX5 mRNA CTD PMID:20816883 phorbol 13-acetate 12-myristate multiple interactions EXP 6480464 [Tetradecanoylphorbol Acetate co-treated with Calcimycin] affects the localization of ALOX5 protein more ... CTD PMID:10779545 and PMID:11698504 pirinixic acid decreases activity EXP 6480464 pirinixic acid analog results in decreased activity of ALOX5 protein CTD PMID:18710209 more ... poly(propylene imine) macromolecule decreases expression EXP 6480464 poly(propyleneimine) analog results in decreased expression of ALOX5 mRNA CTD PMID:16308212 pregnenolone 16alpha-carbonitrile decreases expression ISO Alox5 (Mus musculus) 6480464 Pregnenolone Carbonitrile results in decreased expression of ALOX5 mRNA CTD PMID:22698814 propanal increases expression EXP 6480464 propionaldehyde results in increased expression of ALOX5 mRNA CTD PMID:26079696 propranolol multiple interactions EXP 6480464 1-oleoyl-2-acetoyl-sn-glycerol inhibits the reaction [Propranolol inhibits the reaction [Calcimycin results in increased activity of and results in increased localization of ALOX5 protein]] and Propranolol inhibits the reaction [Calcimycin results in increased activity of and results in increased localization of ALOX5 protein] CTD PMID:18218859 quercetin multiple interactions EXP 6480464 Quercetin inhibits the reaction [ALOX5 protein results in increased chemical synthesis of Leukotriene B4] CTD PMID:18096136 quercetin 3-sulfate multiple interactions EXP 6480464 quercetin 3'-sulfate inhibits the reaction [ALOX5 protein results in increased chemical synthesis of Leukotriene B4] CTD PMID:18096136 raloxifene multiple interactions ISO Alox5 (Mus musculus) 6480464 [APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of ALOX5 mRNA CTD PMID:24431404 reactive oxygen species decreases activity ISO Alox5 (Rattus norvegicus) 6480464 Reactive Oxygen Species results in decreased activity of ALOX5 protein CTD PMID:12388339 reactive oxygen species multiple interactions ISO Alox5 (Rattus norvegicus) 6480464 Nitric Oxide promotes the reaction [Reactive Oxygen Species results in decreased activity of ALOX5 protein] CTD PMID:12388339 rebaudioside A increases expression EXP 6480464 rebaudioside A results in increased expression of ALOX5 mRNA CTD PMID:31655124 resveratrol multiple interactions EXP 6480464 resveratrol binds to and results in decreased activity of ALOX5 protein and resveratrol inhibits the reaction [[Hydrogen Peroxide results in increased activity of ALOX5 protein] which results in increased chemical synthesis of Leukotriene B4] CTD PMID:10491155 resveratrol decreases expression ISO Alox5 (Mus musculus) 6480464 Resveratrol results in decreased expression of ALOX5 protein CTD PMID:23751068 S-(1,2-dichlorovinyl)-L-cysteine multiple interactions EXP 6480464 [S-(1 more ... CTD PMID:35811015 S-(1,2-dichlorovinyl)-L-cysteine decreases expression EXP 6480464 S-(1 and 2-dichlorovinyl)cysteine results in decreased expression of ALOX5 mRNA CTD PMID:35811015 SB 203580 multiple interactions EXP 6480464 SB 203580 inhibits the reaction [Calcimycin results in increased phosphorylation of and results in increased activity of ALOX5 protein] more ... CTD PMID:10779545 SB 203580 multiple interactions ISO Alox5 (Rattus norvegicus) 6480464 SB 203580 inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] affects the localization of ALOX5 protein] and SB 203580 inhibits the reaction [Hydrogen Peroxide affects the localization of ALOX5 protein] CTD PMID:18951527 SB 203580 multiple interactions ISO Alox5 (Mus musculus) 6480464 SB 203580 inhibits the reaction [2-chloroethyl ethyl sulfide results in increased expression of ALOX5 mRNA] CTD PMID:20382172 SB 431542 multiple interactions EXP 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ALOX5 mRNA CTD PMID:27188386 selenium atom multiple interactions ISO Alox5 (Rattus norvegicus) 6480464 [Vitamin E co-treated with Selenium] results in decreased expression of ALOX5 mRNA and [Vitamin E co-treated with Selenium] results in decreased expression of ALOX5 protein CTD PMID:22223226 silicon dioxide decreases expression EXP 6480464 Silicon Dioxide analog results in decreased expression of ALOX5 mRNA CTD PMID:25895662 silicon dioxide increases expression ISO Alox5 (Rattus norvegicus) 6480464 Silicon Dioxide results in increased expression of ALOX5 mRNA CTD PMID:21602193 sodium arsenite increases expression ISO Alox5 (Mus musculus) 6480464 sodium arsenite results in increased expression of ALOX5 mRNA CTD PMID:25065748 sodium arsenite decreases expression ISO Alox5 (Mus musculus) 6480464 sodium arsenite results in decreased expression of ALOX5 mRNA CTD PMID:37682722 sodium arsenite decreases expression EXP 6480464 sodium arsenite results in decreased expression of ALOX5 mRNA CTD PMID:34032870 sodium arsenite multiple interactions EXP 6480464 [sodium arsenite co-treated with Platelet Activating Factor co-treated with Arachidonic Acid] results in increased phosphorylation of and results in increased activity of ALOX5 protein more ... CTD PMID:10779545 sodium chloride multiple interactions ISO Alox5 (Rattus norvegicus) 6480464 [AGT protein co-treated with Sodium Chloride] affects the expression of ALOX5 mRNA CTD PMID:27225954 sodium dichromate decreases expression EXP 6480464 sodium bichromate results in decreased expression of ALOX5 mRNA CTD PMID:17685462 steviol increases expression EXP 6480464 steviol results in increased expression of ALOX5 mRNA CTD PMID:31655124 stevioside increases expression EXP 6480464 stevioside results in increased expression of ALOX5 mRNA CTD PMID:31655124 sunitinib increases expression EXP 6480464 Sunitinib results in increased expression of ALOX5 mRNA CTD PMID:31533062 tamoxifen multiple interactions EXP 6480464 [Tamoxifen results in increased expression of ALOX5 protein] which results in increased abundance of Leukotriene B4 CTD PMID:9742967 tamoxifen increases expression EXP 6480464 Tamoxifen results in increased expression of ALOX5 protein CTD PMID:9742967 tenidap decreases activity EXP 6480464 tenidap results in decreased activity of ALOX5 protein CTD PMID:2849922 tenidap multiple interactions EXP 6480464 [tenidap results in decreased activity of ALOX5 protein] which results in decreased chemical synthesis of Leukotriene B4 more ... CTD PMID:2849922 tepoxalin multiple interactions ISO Alox5 (Rattus norvegicus) 6480464 [tepoxalin results in decreased activity of ALOX5 protein] inhibits the reaction [Indomethacin results in increased abundance of Leukotriene B4] CTD PMID:9223651 tepoxalin decreases activity ISO Alox5 (Rattus norvegicus) 6480464 tepoxalin results in decreased activity of ALOX5 protein CTD PMID:9223651 tepoxalin decreases activity EXP 6480464 tepoxalin results in decreased activity of ALOX5 protein CTD PMID:12629151 tert-butanol multiple interactions EXP 6480464 tert-Butyl Alcohol inhibits the reaction [Calcimycin results in increased activity of and results in increased localization of ALOX5 protein] CTD PMID:18218859 tert-butyl hydroperoxide decreases expression EXP 6480464 tert-Butylhydroperoxide results in decreased expression of ALOX5 mRNA CTD PMID:15336504 testosterone multiple interactions ISO Alox5 (Rattus norvegicus) 6480464 [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of ALOX5 mRNA CTD PMID:32741896 tetrachloromethane multiple interactions ISO Alox5 (Rattus norvegicus) 6480464 2-(4-(quinolin-2-yl-methoxy)phenyl)-2-cyclopentylacetic acid inhibits the reaction [Carbon Tetrachloride results in increased expression of ALOX5 protein] CTD PMID:16033810 tetrachloromethane increases expression ISO Alox5 (Mus musculus) 6480464 Carbon Tetrachloride results in increased expression of ALOX5 protein CTD PMID:25432964 tetrachloromethane multiple interactions ISO Alox5 (Mus musculus) 6480464 PTGS1 gene mutant form promotes the reaction [Carbon Tetrachloride results in increased expression of ALOX5 protein] and SC 560 promotes the reaction [Carbon Tetrachloride results in increased expression of ALOX5 protein] CTD PMID:25432964 tetrachloromethane increases expression ISO Alox5 (Rattus norvegicus) 6480464 Carbon Tetrachloride results in increased expression of ALOX5 protein CTD PMID:16033810 tetraphene increases expression ISO Alox5 (Mus musculus) 6480464 benz(a)anthracene results in increased expression of ALOX5 mRNA CTD PMID:26377693 thapsigargin multiple interactions EXP 6480464 1-Butanol inhibits the reaction [Thapsigargin results in increased activity of and results in increased localization of ALOX5 protein] more ... CTD PMID:10779545 and PMID:18218859 thimerosal decreases expression EXP 6480464 Thimerosal results in decreased expression of ALOX5 mRNA CTD PMID:27188386 thioacetamide increases expression ISO Alox5 (Rattus norvegicus) 6480464 Thioacetamide results in increased expression of ALOX5 mRNA CTD PMID:34492290 titanium dioxide decreases expression ISO Alox5 (Mus musculus) 6480464 titanium dioxide results in decreased expression of ALOX5 mRNA CTD PMID:27760801 titanium dioxide multiple interactions ISO Alox5 (Mus musculus) 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of ALOX5 mRNA CTD PMID:29950665 titanium dioxide increases expression ISO Alox5 (Mus musculus) 6480464 titanium dioxide results in increased expression of ALOX5 mRNA CTD PMID:23409001 trans-caffeic acid multiple interactions ISO Alox5 (Mus musculus) 6480464 caffeic acid inhibits the reaction [aluminum chloride results in increased expression of ALOX5 mRNA] and caffeic acid inhibits the reaction [aluminum chloride results in increased expression of ALOX5 protein] CTD PMID:18482095 trans-caffeic acid multiple interactions ISO Alox5 (Rattus norvegicus) 6480464 caffeic acid inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] affects the localization of ALOX5 protein] more ... CTD PMID:18951527 and PMID:27368151 trichloroethene decreases expression ISO Alox5 (Rattus norvegicus) 6480464 Trichloroethylene results in decreased expression of ALOX5 mRNA CTD PMID:33387578 triclosan increases expression EXP 6480464 Triclosan results in increased expression of ALOX5 mRNA CTD PMID:30510588 trimellitic anhydride decreases expression ISO Alox5 (Mus musculus) 6480464 trimellitic anhydride results in decreased expression of ALOX5 mRNA CTD PMID:19042947 troglitazone decreases activity ISO Alox5 (Rattus norvegicus) 6480464 troglitazone results in decreased activity of ALOX5 protein CTD PMID:10694244 and PMID:17113579 troglitazone multiple interactions ISO Alox5 (Rattus norvegicus) 6480464 [troglitazone results in decreased activity of ALOX5 protein] which results in decreased abundance of Leukotriene B4 CTD PMID:10694244 tyrphostin AG 1478 multiple interactions EXP 6480464 [RTKI cpd co-treated with AG 1879] inhibits the reaction [Nicotine results in increased expression of ALOX5 protein] and RTKI cpd inhibits the reaction [Nicotine results in increased expression of ALOX5 protein] CTD PMID:14569062 tyrphostin AG 1478 multiple interactions ISO Alox5 (Mus musculus) 6480464 RTKI cpd inhibits the reaction [Acrolein results in increased expression of ALOX5 protein] CTD PMID:20153347 valproic acid increases methylation EXP 6480464 Valproic Acid results in increased methylation of ALOX5 gene CTD PMID:29154799 valproic acid multiple interactions EXP 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ALOX5 mRNA CTD PMID:27188386 valproic acid increases expression EXP 6480464 Valproic Acid results in increased expression of ALOX5 mRNA CTD PMID:23179753 more ... vitamin E decreases activity EXP 6480464 Vitamin E results in decreased activity of ALOX5 protein CTD PMID:11325678 and PMID:12200813 vitamin E multiple interactions ISO Alox5 (Rattus norvegicus) 6480464 [Vitamin E co-treated with Selenium] results in decreased expression of ALOX5 mRNA and [Vitamin E co-treated with Selenium] results in decreased expression of ALOX5 protein CTD PMID:22223226 zileuton multiple interactions EXP 6480464 [zileuton results in decreased activity of ALOX5 protein] inhibits the reaction [Calcimycin results in increased abundance of Platelet Activating Factor] more ... CTD PMID:10698703 more ... zileuton decreases activity ISO Alox5 (Rattus norvegicus) 6480464 zileuton results in decreased activity of ALOX5 protein CTD PMID:10694244 more ... zileuton affects response to substance EXP 6480464 ALOX5 gene SNP affects the susceptibility to zileuton CTD PMID:19214143 zileuton decreases activity EXP 6480464 zileuton results in decreased activity of ALOX5 protein CTD PMID:10377029 more ... zileuton decreases expression ISO Alox5 (Rattus norvegicus) 6480464 zileuton results in decreased expression of ALOX5 mRNA CTD PMID:19309543 zileuton multiple interactions ISO Alox5 (Rattus norvegicus) 6480464 [[zileuton co-treated with Calcimycin] results in decreased activity of ALOX5 protein] which results in decreased abundance of Leukotriene B4 more ... CTD PMID:10694244 more ... zileuton multiple interactions ISO Alox5 (Mus musculus) 6480464 [zileuton results in decreased activity of ALOX5 protein] which results in decreased abundance of Leukotriene B4 more ... CTD PMID:11694324 more ... zileuton decreases activity ISO Alox5 (Mus musculus) 6480464 zileuton results in decreased activity of ALOX5 protein CTD PMID:11694324 more ... zinc atom increases expression EXP 6480464 Zinc deficiency results in increased expression of ALOX5 mRNA CTD PMID:22171008 zinc(0) increases expression EXP 6480464 Zinc deficiency results in increased expression of ALOX5 mRNA CTD PMID:22171008 zoledronic acid increases expression EXP 6480464 zoledronic acid results in increased expression of ALOX5 mRNA CTD PMID:24714768
