RPS6KB1 (ribosomal protein S6 kinase, 70kDa, polypeptide 1)

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Keyword

Gene: RPS6KB1 (ribosomal protein S6 kinase, 70kDa, polypeptide 1) Homo sapiens

Symbol:

RPS6KB1

Name:

ribosomal protein S6 kinase, 70kDa, polypeptide 1

Description:

This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17. [provided by RefSeq, Jan 2013]

Type:

protein-coding

RefSeq Status:

REVIEWED

Also known as:

70 kDa ribosomal protein S6 kinase 1; OTTHUMP00000198109; OTTHUMP00000198110; p70 ribosomal S6 kinase alpha; p70 S6 kinase alpha; p70 S6 kinase, alpha; p70 S6 kinase, alpha 1; p70 S6 kinase, alpha 2; p70 S6K-alpha; p70 S6KA; p70 S6KA; p70(S6K)-alpha; p70-alpha; p70-S6K; p70-S6K 1; P70S6K1; PS6K; ribosomal protein S6 kinase beta-1; ribosomal protein S6 kinase I; s6 kinase; S6K; S6K-beta-1; S6K-beta-1; S6K1; serine/threonine kinase 14 alpha; serine/threonine-protein kinase 14A; STK14A

Orthologs:

Rattus norvegicus : Rps6kb1 (ribosomal protein S6 kinase, polypeptide 1)

Latest Assembly:

Human Genome Assembly GRCh37

Position:

Map	Chr	Position	Strand	Source
Human Alternate Assembly CHM1_1	17	58,985,551 - 59,042,891	+	NCBI
Human Genome Assembly HuRef	17	53,342,977 - 53,400,248	+	NCBI
Human Genome Assembly GRCh37	17	57,970,443 - 58,027,787	+	NCBI
Human Genome Assembly Build 36	17	55,325,225 - 55,382,569	+	NCBI
Human Cytogenetic Map	17	q23.1		NCBI
Human Genome Assembly	17	55,325,224 - 55,382,566		NCBI