PTGS1 (prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase))

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Keyword

Gene: PTGS1 (prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)) Homo sapiens

Symbol:

PTGS1

Name:

prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)

Description:

This is one of two genes encoding similar enzymes that catalyze the conversion of arachinodate to prostaglandin. The encoded protein regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. The protein may promote cell proliferation during tumor progression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2012]

Type:

protein-coding

RefSeq Status:

REVIEWED

Also known as:

COX-1; COX1; COX3; cyclooxygenase-1; OTTHUMP00000022052; OTTHUMP00000022053; PCOX1; PES-1; PGG/HS; PGH synthase 1; PGHS-1; PGHS1; PHS 1; PHS1; prostaglandin G/H synthase 1; prostaglandin G/H synthase and cyclooxygenase; prostaglandin H2 synthase 1; prostaglandin-endoperoxide synthase 1; PTGHS

Orthologs:

Mus musculus : Ptgs1 (prostaglandin-endoperoxide synthase 1) MGI
Rattus norvegicus : Ptgs1 (prostaglandin-endoperoxide synthase 1)

Latest Assembly:

Human Genome Assembly GRCh37

Position:

Map	Chr	Position	Strand	Source
Human Alternate Assembly CHM1_1	9	125,144,621 - 125,169,786	+	NCBI
Human Genome Assembly HuRef	9	94,747,532 - 94,772,698	+	NCBI
Human Genome Assembly GRCh37	9	125,132,809 - 125,157,982	+	NCBI
Human Genome Assembly Build 36	9	124,173,050 - 124,197,802	+	NCBI
Human Cytogenetic Map	9	q32-q33.3		NCBI
Human Genome Assembly	9	122,212,782 - 122,237,535		NCBI