CACNG7 (calcium voltage-gated channel auxiliary subunit gamma 7) - Rat Genome Database

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Gene: CACNG7 (calcium voltage-gated channel auxiliary subunit gamma 7) Homo sapiens
Analyze
Symbol: CACNG7
Name: calcium voltage-gated channel auxiliary subunit gamma 7
RGD ID: 732586
HGNC Page HGNC:13626
Description: Enables calcium channel regulator activity. Predicted to be involved in several processes, including neurotransmitter receptor transport, postsynaptic endosome to lysosome; positive regulation of glutamatergic synaptic transmission; and postsynaptic neurotransmitter receptor diffusion trapping. Part of L-type voltage-gated calcium channel complex.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: calcium channel, voltage-dependent, gamma subunit 7; neuronal voltage-gated calcium channel gamma-7 subunit; TARP gamma-7; transmembrane AMPAR regulatory protein gamma-7; voltage-dependent calcium channel gamma-7 subunit
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381953,909,278 - 53,943,950 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1953,909,278 - 53,943,950 (+)EnsemblGRCh38hg38GRCh38
GRCh371954,412,532 - 54,447,204 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361959,107,883 - 59,138,080 (+)NCBINCBI36Build 36hg18NCBI36
Build 341959,107,882 - 59,138,080NCBI
Celera1951,457,105 - 51,485,939 (+)NCBICelera
Cytogenetic Map19q13.42NCBI
HuRef1950,735,318 - 50,764,119 (+)NCBIHuRef
CHM1_11954,417,785 - 54,448,738 (+)NCBICHM1_1
T2T-CHM13v2.01956,988,984 - 57,022,442 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
References

References - curated
# Reference Title Reference Citation
1. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:11170751   PMID:11738816   PMID:11927536   PMID:12477932   PMID:15489334   PMID:17652770   PMID:21127204   PMID:21172611   PMID:21873635   PMID:32296183   PMID:33961781  


Genomics

Comparative Map Data
CACNG7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381953,909,278 - 53,943,950 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1953,909,278 - 53,943,950 (+)EnsemblGRCh38hg38GRCh38
GRCh371954,412,532 - 54,447,204 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361959,107,883 - 59,138,080 (+)NCBINCBI36Build 36hg18NCBI36
Build 341959,107,882 - 59,138,080NCBI
Celera1951,457,105 - 51,485,939 (+)NCBICelera
Cytogenetic Map19q13.42NCBI
HuRef1950,735,318 - 50,764,119 (+)NCBIHuRef
CHM1_11954,417,785 - 54,448,738 (+)NCBICHM1_1
T2T-CHM13v2.01956,988,984 - 57,022,442 (+)NCBIT2T-CHM13v2.0
Cacng7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3973,381,341 - 3,416,737 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl73,381,471 - 3,416,737 (+)EnsemblGRCm39 Ensembl
GRCm3873,332,027 - 3,368,221 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl73,332,955 - 3,368,221 (+)EnsemblGRCm38mm10GRCm38
MGSCv3773,336,685 - 3,366,537 (+)NCBIGRCm37MGSCv37mm9NCBIm37
Celera73,287,413 - 3,318,058 (+)NCBICelera
Cytogenetic Map7A1NCBI
cM Map71.95NCBI
Cacng7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8174,715,483 - 74,746,669 (-)NCBIGRCr8
mRatBN7.2165,800,059 - 65,831,246 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl165,800,355 - 65,831,006 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx171,249,507 - 71,275,759 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0179,672,501 - 79,698,749 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0173,005,758 - 73,032,036 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0164,374,547 - 64,405,380 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl164,374,603 - 64,405,149 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0163,367,593 - 63,397,433 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4164,114,233 - 64,140,485 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1164,191,698 - 64,218,596 (-)NCBI
Celera163,526,185 - 63,552,433 (-)NCBICelera
Cytogenetic Map1q12NCBI
Cacng7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955604241,170 - 260,594 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955604242,627 - 260,594 (-)NCBIChiLan1.0ChiLan1.0
CACNG7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22059,921,106 - 59,952,201 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11961,843,010 - 61,873,991 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01950,849,785 - 50,880,904 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11959,698,941 - 59,726,447 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1959,701,451 - 59,724,809 (+)Ensemblpanpan1.1panPan2
CACNG7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11103,276,743 - 103,293,393 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1103,277,662 - 103,293,995 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1103,338,506 - 103,359,764 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01103,926,808 - 103,948,291 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.11103,559,486 - 103,580,755 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01103,321,255 - 103,342,500 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01104,040,180 - 104,061,457 (-)NCBIUU_Cfam_GSD_1.0
Cacng7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244093492,811,484 - 2,830,589 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936994108,213 - 126,435 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936994107,973 - 126,317 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CACNG7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl656,188,168 - 56,212,505 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1656,188,362 - 56,211,655 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2653,003,529 - 53,027,058 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CACNG7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1646,602,072 - 46,631,975 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl646,605,245 - 46,632,416 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607326,679,331 - 26,709,584 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cacng7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248322,529,705 - 2,546,908 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248322,529,708 - 2,546,916 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in CACNG7
14 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 19q13.33-13.43(chr19:50191219-58535818)x3 copy number gain See cases [RCV000050883] Chr19:50191219..58535818 [GRCh38]
Chr19:50694476..59047185 [GRCh37]
Chr19:55386288..63738997 [NCBI36]
Chr19:19q13.33-13.43		 pathogenic
GRCh38/hg38 19q13.33-13.43(chr19:49907832-58557889)x3 copy number gain See cases [RCV000052925] Chr19:49907832..58557889 [GRCh38]
Chr19:50411089..59069256 [GRCh37]
Chr19:55102901..63761068 [NCBI36]
Chr19:19q13.33-13.43		 pathogenic
GRCh38/hg38 19q13.41-13.43(chr19:51141518-58539965)x3 copy number gain See cases [RCV000052926] Chr19:51141518..58539965 [GRCh38]
Chr19:51644775..59051332 [GRCh37]
Chr19:56336587..63743144 [NCBI36]
Chr19:19q13.41-13.43		 pathogenic
GRCh38/hg38 19q13.33-13.43(chr19:47908540-58539965)x3 copy number gain See cases [RCV000052914] Chr19:47908540..58539965 [GRCh38]
Chr19:48411797..59051332 [GRCh37]
Chr19:53103609..63743144 [NCBI36]
Chr19:19q13.33-13.43		 pathogenic
GRCh38/hg38 19q13.33-13.43(chr19:47929575-58572206)x3 copy number gain See cases [RCV000052915] Chr19:47929575..58572206 [GRCh38]
Chr19:48432832..59083573 [GRCh37]
Chr19:53124644..63775385 [NCBI36]
Chr19:19q13.33-13.43		 pathogenic
NM_031896.4(CACNG7):c.369C>T (p.Ile123=) single nucleotide variant Malignant melanoma [RCV000072339] Chr19:53915450 [GRCh38]
Chr19:54418704 [GRCh37]
Chr19:59110516 [NCBI36]
Chr19:19q13.42		 not provided
NM_031896.4(CACNG7):c.370C>T (p.Arg124Cys) single nucleotide variant Malignant melanoma [RCV000072340] Chr19:53915451 [GRCh38]
Chr19:54418705 [GRCh37]
Chr19:59110517 [NCBI36]
Chr19:19q13.42		 not provided
NM_031896.5(CACNG7):c.784A>G (p.Ile262Val) single nucleotide variant Intellectual disability [RCV001291077] Chr19:53942249 [GRCh38]
Chr19:54445503 [GRCh37]
Chr19:19q13.42		 likely pathogenic
GRCh38/hg38 19q13.41-13.43(chr19:52612432-58581203)x3 copy number gain See cases [RCV000134174] Chr19:52612432..58581203 [GRCh38]
Chr19:53115685..59092570 [GRCh37]
Chr19:57807497..63784382 [NCBI36]
Chr19:19q13.41-13.43		 pathogenic
GRCh38/hg38 19q13.41-13.43(chr19:52955056-58581203)x3 copy number gain See cases [RCV000134139] Chr19:52955056..58581203 [GRCh38]
Chr19:53458309..59092570 [GRCh37]
Chr19:58150121..63784382 [NCBI36]
Chr19:19q13.41-13.43		 pathogenic
GRCh38/hg38 19q13.33-13.43(chr19:50152520-58581203)x3 copy number gain See cases [RCV000135843] Chr19:50152520..58581203 [GRCh38]
Chr19:50655777..59092570 [GRCh37]
Chr19:55347589..63784382 [NCBI36]
Chr19:19q13.33-13.43		 pathogenic
GRCh38/hg38 19q13.41-13.43(chr19:52143873-58445521)x3 copy number gain See cases [RCV000142008] Chr19:52143873..58445521 [GRCh38]
Chr19:52647126..58956888 [GRCh37]
Chr19:57338938..63648700 [NCBI36]
Chr19:19q13.41-13.43		 pathogenic
GRCh37/hg19 19q13.42(chr19:54280799-54486105)x3 copy number gain See cases [RCV000240206] Chr19:54280799..54486105 [GRCh37]
Chr19:19q13.42		 uncertain significance
GRCh37/hg19 19q13.42(chr19:54082353-54486105)x3 copy number gain See cases [RCV000240228] Chr19:54082353..54486105 [GRCh37]
Chr19:19q13.42		 uncertain significance
GRCh37/hg19 19q13.42(chr19:54280799-54635178)x1 copy number loss See cases [RCV000240343] Chr19:54280799..54635178 [GRCh37]
Chr19:19q13.42		 pathogenic
GRCh37/hg19 19q13.33-13.43(chr19:50489390-59095359)x3 copy number gain See cases [RCV000445925] Chr19:50489390..59095359 [GRCh37]
Chr19:19q13.33-13.43		 pathogenic
GRCh37/hg19 19q13.42-13.43(chr19:54344821-58956888)x3 copy number gain See cases [RCV000448186] Chr19:54344821..58956888 [GRCh37]
Chr19:19q13.42-13.43		 pathogenic
GRCh37/hg19 19p13.3-q13.43(chr19:260912-58956888)x3 copy number gain See cases [RCV000511289] Chr19:260912..58956888 [GRCh37]
Chr19:19p13.3-q13.43		 pathogenic|uncertain significance
GRCh37/hg19 19p13.3-q13.43(chr19:260912-58956888) copy number gain See cases [RCV000512296] Chr19:260912..58956888 [GRCh37]
Chr19:19p13.3-q13.43		 pathogenic
GRCh37/hg19 19q13.42(chr19:53867570-55833460)x3 copy number gain not provided [RCV000684091] Chr19:53867570..55833460 [GRCh37]
Chr19:19q13.42		 uncertain significance
GRCh37/hg19 19q13.42-13.43(chr19:54196216-58759679)x3 copy number gain not provided [RCV000684095] Chr19:54196216..58759679 [GRCh37]
Chr19:19q13.42-13.43		 pathogenic
GRCh37/hg19 19q13.42(chr19:54082504-54417191)x3 copy number gain not provided [RCV000684078] Chr19:54082504..54417191 [GRCh37]
Chr19:19q13.42		 uncertain significance
GRCh37/hg19 19p13.3-q13.43(chr19:68029-59110290)x3 copy number gain not provided [RCV000752439] Chr19:68029..59110290 [GRCh37]
Chr19:19p13.3-q13.43		 pathogenic
GRCh37/hg19 19p13.3-q13.43(chr19:260912-59097160)x3 copy number gain not provided [RCV000752444] Chr19:260912..59097160 [GRCh37]
Chr19:19p13.3-q13.43		 pathogenic
GRCh37/hg19 19q13.33-13.43(chr19:50740074-59097160)x3 copy number gain not provided [RCV000740208] Chr19:50740074..59097160 [GRCh37]
Chr19:19q13.33-13.43		 pathogenic
NM_031896.5(CACNG7):c.380G>A (p.Arg127Lys) single nucleotide variant Inborn genetic diseases [RCV003268370] Chr19:53915461 [GRCh38]
Chr19:54418715 [GRCh37]
Chr19:19q13.42		 uncertain significance
NC_000019.10:g.53536530_53981185dup duplication Silver Russell Syndrome-related disorder [RCV000785667] Chr19:53536530..53981185 [GRCh38]
Chr19:54039784..54484439 [GRCh37]
Chr19:19q13.42		 uncertain significance
GRCh37/hg19 19q13.32-13.42(chr19:47939842-54626871) copy number gain not provided [RCV001249294] Chr19:47939842..54626871 [GRCh37]
Chr19:19q13.32-13.42		 not provided
GRCh37/hg19 19q13.42-13.43(chr19:54334195-56434037)x3 copy number gain not provided [RCV001259948] Chr19:54334195..56434037 [GRCh37]
Chr19:19q13.42-13.43		 uncertain significance
GRCh37/hg19 19q13.33-13.43(chr19:48463931-57095254)x3 copy number gain not provided [RCV001259944] Chr19:48463931..57095254 [GRCh37]
Chr19:19q13.33-13.43		 pathogenic
NC_000019.9:g.(?_54297303)_(55678016_?)dup duplication not provided [RCV001981426] Chr19:54297303..55678016 [GRCh37]
Chr19:19q13.42		 uncertain significance
NM_031896.5(CACNG7):c.200G>A (p.Arg67Gln) single nucleotide variant Inborn genetic diseases [RCV002883130] Chr19:53914503 [GRCh38]
Chr19:54417757 [GRCh37]
Chr19:19q13.42		 uncertain significance
NM_031896.5(CACNG7):c.797A>G (p.Asp266Gly) single nucleotide variant Inborn genetic diseases [RCV002729381] Chr19:53942262 [GRCh38]
Chr19:54445516 [GRCh37]
Chr19:19q13.42		 uncertain significance
NM_031896.5(CACNG7):c.147G>T (p.Glu49Asp) single nucleotide variant Inborn genetic diseases [RCV002777982] Chr19:53912978 [GRCh38]
Chr19:54416232 [GRCh37]
Chr19:19q13.42		 uncertain significance
NM_031896.5(CACNG7):c.22G>C (p.Ala8Pro) single nucleotide variant Inborn genetic diseases [RCV002949799] Chr19:53912853 [GRCh38]
Chr19:54416107 [GRCh37]
Chr19:19q13.42		 uncertain significance
NM_031896.5(CACNG7):c.726C>G (p.Ser242Arg) single nucleotide variant Inborn genetic diseases [RCV002743079] Chr19:53942191 [GRCh38]
Chr19:54445445 [GRCh37]
Chr19:19q13.42		 uncertain significance
NM_031896.5(CACNG7):c.242C>T (p.Pro81Leu) single nucleotide variant Inborn genetic diseases [RCV002703053] Chr19:53914545 [GRCh38]
Chr19:54417799 [GRCh37]
Chr19:19q13.42		 uncertain significance
NM_031896.5(CACNG7):c.199C>T (p.Arg67Trp) single nucleotide variant Inborn genetic diseases [RCV003184634] Chr19:53914502 [GRCh38]
Chr19:54417756 [GRCh37]
Chr19:19q13.42		 uncertain significance
NM_031896.5(CACNG7):c.698A>G (p.Gln233Arg) single nucleotide variant Inborn genetic diseases [RCV003383776] Chr19:53942163 [GRCh38]
Chr19:54445417 [GRCh37]
Chr19:19q13.42		 uncertain significance
GRCh37/hg19 19q13.33-13.43(chr19:49625130-57647352)x3 copy number gain not provided [RCV003485200] Chr19:49625130..57647352 [GRCh37]
Chr19:19q13.33-13.43		 likely pathogenic
GRCh37/hg19 19q13.42(chr19:53963333-54421591)x3 copy number gain not provided [RCV003485201] Chr19:53963333..54421591 [GRCh37]
Chr19:19q13.42		 uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2073
Count of miRNA genes:831
Interacting mature miRNAs:973
Transcripts:ENST00000222212, ENST00000391766, ENST00000391767, ENST00000468076
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
ECD00160  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371954,414,675 - 54,415,604UniSTSGRCh37
Build 361959,106,487 - 59,107,416RGDNCBI36
Celera1951,455,709 - 51,456,638RGD
Cytogenetic Map19q13.4UniSTS
HuRef1950,734,002 - 50,734,931UniSTS
ECD00198  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371954,415,627 - 54,416,551UniSTSGRCh37
Build 361959,107,439 - 59,108,363RGDNCBI36
Celera1951,456,661 - 51,457,585RGD
Cytogenetic Map19q13.4UniSTS
HuRef1950,734,954 - 50,735,878UniSTS
ECD08160  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371954,445,209 - 54,445,871UniSTSGRCh37
Build 361959,137,021 - 59,137,683RGDNCBI36
Celera1951,484,881 - 51,485,542RGD
Cytogenetic Map19q13.4UniSTS
HuRef1950,762,367 - 50,763,028UniSTS
ECD11069  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371954,445,976 - 54,446,559UniSTSGRCh37
Build 361959,137,788 - 59,138,371RGDNCBI36
Celera1951,485,647 - 51,486,230RGD
Cytogenetic Map19q13.4UniSTS
HuRef1950,763,133 - 50,763,716UniSTS
ECD13063  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371954,444,396 - 54,444,923UniSTSGRCh37
Build 361959,136,208 - 59,136,735RGDNCBI36
Celera1951,484,068 - 51,484,595RGD
Cytogenetic Map19q13.4UniSTS
HuRef1950,761,553 - 50,762,081UniSTS
ECD16533  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371954,418,336 - 54,418,772UniSTSGRCh37
Build 361959,110,148 - 59,110,584RGDNCBI36
Celera1951,459,370 - 51,459,806RGD
Cytogenetic Map19q13.4UniSTS
HuRef1950,737,663 - 50,738,099UniSTS
ECD17455  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371954,420,585 - 54,420,983UniSTSGRCh37
Build 361959,112,397 - 59,112,795RGDNCBI36
Celera1951,461,619 - 51,462,017RGD
Cytogenetic Map19q13.4UniSTS
HuRef1950,739,913 - 50,740,311UniSTS
ECD18300  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371954,417,567 - 54,417,932UniSTSGRCh37
Build 361959,109,379 - 59,109,744RGDNCBI36
Celera1951,458,601 - 51,458,966RGD
Cytogenetic Map19q13.4UniSTS
HuRef1950,736,894 - 50,737,259UniSTS
ECD18583  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371954,431,161 - 54,431,515UniSTSGRCh37
Build 361959,122,973 - 59,123,327RGDNCBI36
Celera1951,470,844 - 51,471,198RGD
Cytogenetic Map19q13.4UniSTS
HuRef1950,748,453 - 50,748,807UniSTS
ECD19678  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371954,430,473 - 54,430,786UniSTSGRCh37
Build 361959,122,285 - 59,122,598RGDNCBI36
Celera1951,470,156 - 51,470,469RGD
Cytogenetic Map19q13.4UniSTS
HuRef1950,747,765 - 50,748,078UniSTS
ECD22303  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371954,443,260 - 54,443,483UniSTSGRCh37
Build 361959,135,072 - 59,135,295RGDNCBI36
Celera1951,482,933 - 51,483,156RGD
Cytogenetic Map19q13.4UniSTS
HuRef1950,760,418 - 50,760,641UniSTS
stSG605644  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371954,414,279 - 54,415,443UniSTSGRCh37
Build 361959,106,091 - 59,107,255RGDNCBI36
Celera1951,455,313 - 51,456,477RGD
Cytogenetic Map19q13.4UniSTS
HuRef1950,733,606 - 50,734,770UniSTS
stSG605645  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371954,415,425 - 54,416,551UniSTSGRCh37
Build 361959,107,237 - 59,108,363RGDNCBI36
Celera1951,456,459 - 51,457,585RGD
Cytogenetic Map19q13.4UniSTS
HuRef1950,734,752 - 50,735,878UniSTS
stSG605647  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371954,417,864 - 54,419,288UniSTSGRCh37
Build 361959,109,676 - 59,111,100RGDNCBI36
Celera1951,458,898 - 51,460,322RGD
Cytogenetic Map19q13.4UniSTS
HuRef1950,737,191 - 50,738,615UniSTS
stSG605648  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371954,419,358 - 54,420,662UniSTSGRCh37
Build 361959,111,170 - 59,112,474RGDNCBI36
Celera1951,460,392 - 51,461,696RGD
Cytogenetic Map19q13.4UniSTS
HuRef1950,738,685 - 50,739,990UniSTS
stSG605649  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371954,420,659 - 54,421,858UniSTSGRCh37
Build 361959,112,471 - 59,113,670RGDNCBI36
Celera1951,461,693 - 51,462,892RGD
Cytogenetic Map19q13.4UniSTS
HuRef1950,739,987 - 50,741,186UniSTS
stSG605656  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371954,429,073 - 54,430,204UniSTSGRCh37
Build 361959,120,885 - 59,122,016RGDNCBI36
Celera1951,468,757 - 51,469,887RGD
Cytogenetic Map19q13.4UniSTS
HuRef1950,746,365 - 50,747,496UniSTS
stSG605657  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371954,430,185 - 54,431,406UniSTSGRCh37
Build 361959,121,997 - 59,123,218RGDNCBI36
Celera1951,469,868 - 51,471,089RGD
Cytogenetic Map19q13.4UniSTS
HuRef1950,747,477 - 50,748,698UniSTS
stSG605660  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371954,437,083 - 54,438,111UniSTSGRCh37
Build 361959,128,895 - 59,129,923RGDNCBI36
Celera1951,476,766 - 51,477,794RGD
Cytogenetic Map19q13.4UniSTS
HuRef1950,754,260 - 50,755,288UniSTS
stSG605662  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371954,443,260 - 54,444,387UniSTSGRCh37
Build 361959,135,072 - 59,136,199RGDNCBI36
Celera1951,482,933 - 51,484,059RGD
Cytogenetic Map19q13.4UniSTS
HuRef1950,760,418 - 50,761,544UniSTS
stSG605663  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371954,444,513 - 54,445,757UniSTSGRCh37
Build 361959,136,325 - 59,137,569RGDNCBI36
Celera1951,484,185 - 51,485,428RGD
Cytogenetic Map19q13.4UniSTS
HuRef1950,761,670 - 50,762,914UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component
High
Medium 4 186 2 6 2 184 9 2900 4 19 12
Low 501 37 142 12 49 14 75 131 191 20 435 56 5 1 12 45
Below cutoff 1700 2282 880 256 990 147 2955 1676 559 127 677 1064 113 832 2055 2

Sequence


Reference Sequences
RefSeq Acc Id: ENST00000222212   ⟹   ENSP00000222212
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1953,912,737 - 53,942,386 (+)Ensembl
RefSeq Acc Id: ENST00000391766   ⟹   ENSP00000375646
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1953,912,817 - 53,941,661 (+)Ensembl
RefSeq Acc Id: ENST00000391767   ⟹   ENSP00000375647
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1953,909,278 - 53,943,950 (+)Ensembl
RefSeq Acc Id: ENST00000468076
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1953,909,335 - 53,941,593 (+)Ensembl
RefSeq Acc Id: NM_001384801   ⟹   NP_001371730
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381953,909,278 - 53,943,950 (+)NCBI
T2T-CHM13v2.01956,988,984 - 57,022,442 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001412134   ⟹   NP_001399063
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01956,988,984 - 57,022,442 (+)NCBI
RefSeq Acc Id: NM_031896   ⟹   NP_114102
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381953,909,278 - 53,943,950 (+)NCBI
GRCh371954,412,704 - 54,447,195 (+)NCBI
Build 361959,107,883 - 59,138,080 (+)NCBI Archive
Celera1951,457,105 - 51,485,939 (+)RGD
HuRef1950,735,318 - 50,764,119 (+)ENTREZGENE
CHM1_11954,417,785 - 54,448,738 (+)NCBI
T2T-CHM13v2.01956,988,984 - 57,022,442 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_114102   ⟸   NM_031896
- Peptide Label: isoform 1
- UniProtKB: Q8WXS6 (UniProtKB/Swiss-Prot),   Q8VBX3 (UniProtKB/Swiss-Prot),   Q52LL8 (UniProtKB/Swiss-Prot),   Q9BXT1 (UniProtKB/Swiss-Prot),   P62955 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSP00000375646   ⟸   ENST00000391766
RefSeq Acc Id: ENSP00000375647   ⟸   ENST00000391767
RefSeq Acc Id: ENSP00000222212   ⟸   ENST00000222212
RefSeq Acc Id: NP_001371730   ⟸   NM_001384801
- Peptide Label: isoform 2
RefSeq Acc Id: NP_001399063   ⟸   NM_001412134
- Peptide Label: isoform 3

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P62955-F1-model_v2 AlphaFold P62955 1-275 view protein structure


Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:13626 AgrOrtholog
COSMIC CACNG7 COSMIC
Ensembl Genes ENSG00000105605 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000222212.6 UniProtKB/Swiss-Prot
  ENST00000391766.1 UniProtKB/TrEMBL
  ENST00000391767 ENTREZGENE
  ENST00000391767.6 UniProtKB/Swiss-Prot
Gene3D-CATH 1.20.140.150 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000105605 GTEx
HGNC ID HGNC:13626 ENTREZGENE
Human Proteome Map CACNG7 Human Proteome Map
InterPro PMP22/EMP/MP20/Claudin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  VDCC_g7su UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  VDCC_gsu UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:59284 UniProtKB/Swiss-Prot
NCBI Gene 59284 ENTREZGENE
OMIM 606899 OMIM
PANTHER PTHR12107:SF12 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA SUBUNIT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Claudin_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA26021 PharmGKB
PRINTS VDCCGAMMA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  VDCCGAMMA7 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE PROKAR_LIPOPROTEIN UniProtKB/TrEMBL
UniProt A0A0C4DFY2_HUMAN UniProtKB/TrEMBL
  CCG7_HUMAN UniProtKB/Swiss-Prot, ENTREZGENE
  Q52LL8 ENTREZGENE
  Q8VBX3 ENTREZGENE
  Q8WXS6 ENTREZGENE
  Q9BXT1 ENTREZGENE
UniProt Secondary Q52LL8 UniProtKB/Swiss-Prot
  Q8VBX3 UniProtKB/Swiss-Prot
  Q8WXS6 UniProtKB/Swiss-Prot
  Q9BXT1 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-10 CACNG7  calcium voltage-gated channel auxiliary subunit gamma 7    calcium channel, voltage-dependent, gamma subunit 7  Symbol and/or name change 5135510 APPROVED