(+)-albicanol multiple interactions ISO Keap1 (Mus musculus) 6480464 albicanol inhibits the reaction [Galactose results in increased expression of KEAP1 mRNA] and albicanol inhibits the reaction [Galactose results in increased expression of KEAP1 protein] CTD PMID:33761044 (-)-epigallocatechin 3-gallate multiple interactions EXP 6480464 epigallocatechin gallate promotes the reaction [arsenite results in increased expression of KEAP1 mRNA] CTD PMID:29572906 (-)-epigallocatechin 3-gallate increases expression EXP 6480464 epigallocatechin gallate results in increased expression of KEAP1 protein CTD PMID:35218280 (R)-lipoic acid increases expression EXP 6480464 Thioctic Acid results in increased expression of KEAP1 protein CTD PMID:19033392 (R)-lipoic acid multiple interactions ISO Keap1 (Mus musculus) 6480464 Thioctic Acid inhibits the reaction [Silicon results in increased expression of KEAP1 protein] CTD PMID:34252510 (R,R,R)-alpha-tocopherol multiple interactions EXP 6480464 alpha-Tocopherol inhibits the reaction [Hydrogen Peroxide results in increased expression of KEAP1 mRNA] and alpha-Tocopherol inhibits the reaction [Hydrogen Peroxide results in increased expression of KEAP1 protein] CTD PMID:36058301 1,2-dimethylhydrazine multiple interactions ISO Keap1 (Mus musculus) 6480464 [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of KEAP1 mRNA CTD PMID:22206623 1,2-naphthoquinone affects response to substance ISO Keap1 (Mus musculus) 6480464 KEAP1 protein affects the susceptibility to 1 and 2-naphthoquinone CTD PMID:21384861 1,2-naphthoquinone increases metabolic processing ISO Keap1 (Mus musculus) 6480464 1 and 2-naphthoquinone results in increased metabolism of KEAP1 protein CTD PMID:21384861 and PMID:25807370 1-chloro-2,4-dinitrobenzene multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [Dinitrochlorobenzene results in increased expression of KEAP1 protein] more ... CTD PMID:19033392 and PMID:25742418 1-chloro-2,4-dinitrobenzene decreases expression ISO Keap1 (Mus musculus) 6480464 Dinitrochlorobenzene results in decreased expression of KEAP1 mRNA CTD PMID:28219650 1-chloro-2,4-dinitrobenzene increases expression EXP 6480464 Dinitrochlorobenzene results in increased expression of KEAP1 protein CTD PMID:19033392 1-chloro-2,4-dinitrobenzene affects metabolic processing ISO Keap1 (Mus musculus) 6480464 Dinitrochlorobenzene affects the metabolism of KEAP1 protein CTD PMID:18785192 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine decreases expression ISO Keap1 (Mus musculus) 6480464 1-Methyl-4-phenyl-1 more ... CTD PMID:33368846 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine increases expression ISO Keap1 (Mus musculus) 6480464 1-Methyl-4-phenyl-1 more ... CTD PMID:38016618 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine multiple interactions ISO Keap1 (Mus musculus) 6480464 1 more ... CTD PMID:33368846 and PMID:38016618 1-naphthyl isothiocyanate decreases expression ISO Keap1 (Mus musculus) 6480464 1-Naphthylisothiocyanate results in decreased expression of KEAP1 mRNA and 1-Naphthylisothiocyanate results in decreased expression of KEAP1 protein CTD PMID:36008890 and PMID:37348807 1-naphthyl isothiocyanate multiple interactions ISO Keap1 (Mus musculus) 6480464 liquiritin promotes the reaction [1-Naphthylisothiocyanate results in decreased expression of KEAP1 protein] CTD PMID:36008890 2'-(4-ethoxyphenyl)-5-(4-methylpiperazin-1-yl)-2,5'-bibenzimidazole decreases export EXP 6480464 KEAP1 protein results in decreased export of bisbenzimide ethoxide trihydrochloride CTD PMID:25841332 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Keap1 (Mus musculus) 6480464 Tetrachlorodibenzodioxin affects the expression of KEAP1 mRNA CTD PMID:21570461 2,4-di-tert-butylphenol multiple interactions EXP 6480464 [SAG compound co-treated with 2 and 4-di-tert-butylphenol co-treated with Fibroblast Growth Factor 2] results in increased expression of KEAP1 mRNA CTD PMID:36682590 2,4-dinitrotoluene affects expression ISO Keap1 (Rattus norvegicus) 6480464 2 and 4-dinitrotoluene affects the expression of KEAP1 mRNA CTD PMID:21346803 2,5-dihydroxybenzoic acid multiple interactions ISO Keap1 (Mus musculus) 6480464 2 and 5-dihydroxybenzoic acid promotes the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of KEAP1 mRNA] CTD PMID:37120126 2-amino-2-deoxy-D-galactopyranose multiple interactions ISO Keap1 (Mus musculus) 6480464 8-oxoberberine promotes the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased degradation of KEAP1 protein] more ... CTD PMID:35691465 2-tert-butylhydroquinone increases expression EXP 6480464 2-tert-butylhydroquinone results in increased expression of KEAP1 protein CTD PMID:19033392 2-tert-butylhydroquinone increases expression ISO Keap1 (Rattus norvegicus) 6480464 2-tert-butylhydroquinone results in increased expression of KEAP1 protein CTD PMID:31726083 2-tert-butylhydroquinone multiple interactions ISO Keap1 (Rattus norvegicus) 6480464 2-tert-butylhydroquinone promotes the reaction [thallium nitrate results in decreased expression of KEAP1 protein] CTD PMID:31726083 2-tert-butylhydroquinone decreases response to substance EXP 6480464 KEAP1 protein mutant form results in decreased susceptibility to 2-tert-butylhydroquinone CTD PMID:23589329 2-tert-butylhydroquinone multiple interactions EXP 6480464 2-tert-butylhydroquinone inhibits the reaction [KEAP1 protein binds to CUL3 protein] more ... CTD PMID:18417180 and PMID:23589329 2-tert-butylhydroquinone affects binding ISO Keap1 (Mus musculus) 6480464 2-tert-butylhydroquinone binds to KEAP1 protein CTD PMID:19808700 2-tert-butylhydroquinone multiple interactions ISO Keap1 (Mus musculus) 6480464 2-tert-butylhydroquinone inhibits the reaction [2 more ... CTD PMID:18512965 more ... 3,3',4,4',5-pentachlorobiphenyl decreases expression EXP 6480464 3 more ... CTD PMID:24709675 3,3',4,4',5-pentachlorobiphenyl affects expression ISO Keap1 (Mus musculus) 6480464 3 more ... CTD PMID:31563530 3,3',4,4',5-pentachlorobiphenyl multiple interactions EXP 6480464 3 more ... CTD PMID:24709675 3,4-methylenedioxymethamphetamine decreases expression ISO Keap1 (Mus musculus) 6480464 N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased expression of KEAP1 mRNA CTD PMID:26251327 3,4-methylenedioxymethamphetamine increases methylation ISO Keap1 (Mus musculus) 6480464 N-Methyl-3 and 4-methylenedioxyamphetamine results in increased methylation of KEAP1 promoter CTD PMID:26251327 3,5-diethoxycarbonyl-1,4-dihydrocollidine decreases response to substance ISO Keap1 (Mus musculus) 6480464 KEAP1 gene mutant form results in decreased susceptibility to 3 more ... CTD PMID:30825315 3,5-diethoxycarbonyl-1,4-dihydrocollidine multiple interactions ISO Keap1 (Mus musculus) 6480464 KEAP1 gene mutant form promotes the reaction [3 more ... CTD PMID:30825315 3,5-diethoxycarbonyl-1,4-dihydrocollidine affects response to substance ISO Keap1 (Mus musculus) 6480464 KEAP1 gene affects the susceptibility to 3 more ... CTD PMID:30215777 3-chloropropane-1,2-diol increases expression ISO Keap1 (Rattus norvegicus) 6480464 alpha-Chlorohydrin results in increased expression of KEAP1 protein CTD PMID:34915118 3-methyladenine decreases expression EXP 6480464 3-methyladenine results in decreased expression of KEAP1 protein CTD PMID:29781141 3-methylcholanthrene increases expression ISO Keap1 (Mus musculus) 6480464 Methylcholanthrene results in increased expression of KEAP1 mRNA CTD PMID:23712962 3-phenylprop-2-enal affects expression ISO Keap1 (Mus musculus) 6480464 cinnamaldehyde affects the expression of KEAP1 mRNA CTD PMID:28219650 3-phenylprop-2-enal increases expression EXP 6480464 cinnamaldehyde results in increased expression of KEAP1 protein CTD PMID:19033392 4,4'-diaminodiphenylmethane decreases expression ISO Keap1 (Mus musculus) 6480464 4 and 4'-diaminodiphenylmethane results in decreased expression of KEAP1 mRNA CTD PMID:18648102 4,4'-dipyridyl disulfide multiple interactions ISO Keap1 (Mus musculus) 6480464 4 more ... CTD PMID:15865434 4,4'-sulfonyldiphenol increases expression ISO Keap1 (Mus musculus) 6480464 bisphenol S results in increased expression of KEAP1 mRNA and bisphenol S results in increased expression of KEAP1 protein CTD PMID:36541330 4,4'-sulfonyldiphenol decreases methylation EXP 6480464 bisphenol S results in decreased methylation of KEAP1 gene CTD PMID:31601247 4-amino-2,6-dinitrotoluene affects expression ISO Keap1 (Rattus norvegicus) 6480464 4-amino-2 and 6-dinitrotoluene affects the expression of KEAP1 mRNA CTD PMID:21346803 5-aza-2'-deoxycytidine multiple interactions EXP 6480464 [Decitabine affects the methylation of KEAP1 promoter] which affects the expression of KEAP1 mRNA more ... CTD PMID:18555005 and PMID:26409248 5-aza-2'-deoxycytidine increases expression EXP 6480464 Decitabine results in increased expression of KEAP1 mRNA CTD PMID:20124447 5-fluorouracil affects response to substance EXP 6480464 KEAP1 protein affects the susceptibility to Fluorouracil CTD PMID:18692501 7,12-dimethyltetraphene multiple interactions ISO Keap1 (Rattus norvegicus) 6480464 betulin inhibits the reaction [9 more ... CTD PMID:24995432 and PMID:33759307 7,12-dimethyltetraphene increases expression ISO Keap1 (Rattus norvegicus) 6480464 9 more ... CTD PMID:24995432 and PMID:33759307 7,8-dihydroxycoumarin decreases expression EXP 6480464 daphnetin results in decreased expression of KEAP1 protein CTD PMID:30738023 [6]-Shogaol decreases expression EXP 6480464 shogaol metabolite results in decreased expression of KEAP1 protein and shogaol results in decreased expression of KEAP1 protein CTD PMID:25148906 [6]-Shogaol multiple interactions ISO Keap1 (Mus musculus) 6480464 KEAP1 protein affects the reaction [shogaol analog results in increased expression of HMOX1 protein] more ... CTD PMID:23899529 [6]-Shogaol increases alkylation EXP 6480464 shogaol results in increased alkylation of KEAP1 protein CTD PMID:25148906 acrolein multiple interactions EXP 6480464 [KEAP1 gene mutant form results in increased activity of NFE2L2] which results in decreased susceptibility to Acrolein and Buthionine Sulfoximine inhibits the reaction [[KEAP1 gene mutant form results in increased activity of NFE2L2] which results in decreased susceptibility to Acrolein] CTD PMID:19608619 acrolein multiple interactions ISO Keap1 (Mus musculus) 6480464 [Ovalbumin co-treated with Acrolein] results in increased expression of KEAP1 protein CTD PMID:30608172 acrolein increases expression ISO Keap1 (Mus musculus) 6480464 Acrolein results in increased expression of KEAP1 protein CTD PMID:30608172 acrylamide affects expression ISO Keap1 (Rattus norvegicus) 6480464 Acrylamide affects the expression of KEAP1 protein CTD PMID:29426002 acrylamide multiple interactions ISO Keap1 (Mus musculus) 6480464 [NLRP3 gene mutant form affects the susceptibility to Acrylamide] which results in increased expression of KEAP1 protein and Acrylamide inhibits the reaction [Streptozocin results in increased expression of KEAP1 mRNA] CTD PMID:32014472 and PMID:34896238 acrylamide increases expression ISO Keap1 (Mus musculus) 6480464 Acrylamide results in increased expression of KEAP1 mRNA CTD PMID:34896238 Aescin multiple interactions ISO Keap1 (Mus musculus) 6480464 Escin inhibits the reaction [Dietary Fats results in increased expression of KEAP1 protein] more ... CTD PMID:36905866 Aescin multiple interactions EXP 6480464 Escin inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of KEAP1 protein] CTD PMID:36905866 Aescin increases expression ISO Keap1 (Mus musculus) 6480464 Escin results in increased expression of KEAP1 protein CTD PMID:36905866 aflatoxin B1 multiple interactions ISO Keap1 (Mus musculus) 6480464 Curcumin inhibits the reaction [Aflatoxin B1 results in decreased expression of KEAP1 mRNA] and Curcumin inhibits the reaction [Aflatoxin B1 results in decreased expression of KEAP1 protein] CTD PMID:35063475 aflatoxin B1 multiple interactions ISO Keap1 (Rattus norvegicus) 6480464 [Aflatoxin B1 co-treated with caryophyllene] results in increased expression of KEAP1 protein CTD PMID:34506763 aflatoxin B1 decreases expression ISO Keap1 (Mus musculus) 6480464 Aflatoxin B1 results in decreased expression of KEAP1 mRNA and Aflatoxin B1 results in decreased expression of KEAP1 protein CTD PMID:35063475 aldehydo-D-glucose multiple interactions ISO Keap1 (Mus musculus) 6480464 [NFE2L2 protein co-treated with KEAP1 protein] affects the abundance of Glucose CTD PMID:23017736 aldehydo-D-glucose multiple interactions EXP 6480464 solanesol inhibits the reaction [Glucose results in increased expression of KEAP1 mRNA] and solanesol inhibits the reaction [Glucose results in increased expression of KEAP1 protein] CTD PMID:37586544 aldehydo-D-glucose increases expression EXP 6480464 Glucose results in increased expression of KEAP1 mRNA and Glucose results in increased expression of KEAP1 protein CTD PMID:37586544 aldehydo-D-glucose multiple interactions ISO Keap1 (Rattus norvegicus) 6480464 [Oxygen deficiency co-treated with Glucose deficiency] results in decreased expression of KEAP1 protein more ... CTD PMID:35191607 all-trans-retinoic acid multiple interactions EXP 6480464 [Tretinoin co-treated with arsenic trioxide] results in increased expression of KEAP1 mRNA CTD PMID:15894607 all-trans-retinoic acid increases expression ISO Keap1 (Rattus norvegicus) 6480464 Tretinoin results in increased expression of KEAP1 protein CTD PMID:30267739 alpha,alpha-trehalose multiple interactions ISO Keap1 (Rattus norvegicus) 6480464 Trehalose inhibits the reaction [cadmium acetate results in decreased expression of KEAP1 protein] CTD PMID:29140578 alpha-D-galactose multiple interactions ISO Keap1 (Mus musculus) 6480464 albicanol inhibits the reaction [Galactose results in increased expression of KEAP1 mRNA] and albicanol inhibits the reaction [Galactose results in increased expression of KEAP1 protein] CTD PMID:33761044 alpha-D-galactose increases expression ISO Keap1 (Mus musculus) 6480464 Galactose results in increased expression of KEAP1 mRNA and Galactose results in increased expression of KEAP1 protein CTD PMID:33761044 Altertoxin II multiple interactions EXP 6480464 altertoxin II results in increased expression of and affects the localization of KEAP1 protein CTD PMID:27178040 amiodarone decreases expression ISO Keap1 (Rattus norvegicus) 6480464 Amiodarone results in decreased expression of KEAP1 mRNA CTD PMID:17991464 amitraz multiple interactions ISO Keap1 (Rattus norvegicus) 6480464 KEAP1 protein affects the reaction [amitraz results in decreased expression of CAT protein] more ... CTD PMID:31029719 amitraz increases expression ISO Keap1 (Rattus norvegicus) 6480464 amitraz results in increased expression of KEAP1 protein CTD PMID:31029719 ammonium chloride affects expression ISO Keap1 (Rattus norvegicus) 6480464 Ammonium Chloride affects the expression of KEAP1 mRNA CTD PMID:16483693 Ammothamnine multiple interactions ISO Keap1 (Mus musculus) 6480464 [oxymatrine inhibits the reaction [KEAP1 protein binds to NFE2L2 protein]] which results in increased stability of and results in increased localization of NFE2L2 protein and oxymatrine inhibits the reaction [KEAP1 protein binds to NFE2L2 protein] CTD PMID:37196756 andrographolide decreases expression EXP 6480464 andrographolide results in decreased expression of KEAP1 mRNA and andrographolide results in decreased expression of KEAP1 protein CTD PMID:29355602 and PMID:35724838 anethole multiple interactions ISO Keap1 (Rattus norvegicus) 6480464 anethole inhibits the reaction [Isoproterenol results in increased expression of KEAP1 mRNA] and anethole inhibits the reaction [Isoproterenol results in increased expression of KEAP1 protein] CTD PMID:35430261 anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions EXP 6480464 pyrazolanthrone inhibits the reaction [pachastrissamine analog promotes the reaction [KEAP1 protein binds to SQSTM1 protein]] CTD PMID:35123989 aristolochic acid A increases expression ISO Keap1 (Mus musculus) 6480464 aristolochic acid I results in increased expression of KEAP1 protein CTD PMID:24530882 aristolochic acid A multiple interactions ISO Keap1 (Rattus norvegicus) 6480464 Curcumin inhibits the reaction [aristolochic acid I results in decreased expression of KEAP1 mRNA] and Curcumin inhibits the reaction [aristolochic acid I results in decreased expression of KEAP1 protein] CTD PMID:36037877 aristolochic acid A decreases expression ISO Keap1 (Rattus norvegicus) 6480464 aristolochic acid I results in decreased expression of KEAP1 mRNA and aristolochic acid I results in decreased expression of KEAP1 protein CTD PMID:36037877 aristolochic acid A increases expression EXP 6480464 aristolochic acid I results in increased expression of KEAP1 mRNA CTD PMID:33212167 aristolochic acid A multiple interactions ISO Keap1 (Mus musculus) 6480464 bardoxolone methyl inhibits the reaction [aristolochic acid I results in increased expression of KEAP1 protein] CTD PMID:24530882 arotinoid acid multiple interactions EXP 6480464 [4-(2-(5 more ... CTD PMID:34480604 arsane affects response to substance ISO Keap1 (Mus musculus) 6480464 KEAP1 protein affects the susceptibility to Arsenic CTD PMID:19808700 arsane increases methylation EXP 6480464 Arsenic results in increased methylation of KEAP1 promoter CTD PMID:29247444 arsane affects binding ISO Keap1 (Mus musculus) 6480464 Arsenic binds to KEAP1 protein CTD PMID:19808700 arsane increases expression EXP 6480464 Arsenic results in increased expression of KEAP1 mRNA and Arsenic results in increased expression of KEAP1 protein CTD PMID:14567983 arsenic atom increases expression EXP 6480464 Arsenic results in increased expression of KEAP1 mRNA and Arsenic results in increased expression of KEAP1 protein CTD PMID:14567983 arsenic atom increases methylation EXP 6480464 Arsenic results in increased methylation of KEAP1 promoter CTD PMID:29247444 arsenic atom affects response to substance ISO Keap1 (Mus musculus) 6480464 KEAP1 protein affects the susceptibility to Arsenic CTD PMID:19808700 arsenic atom affects binding ISO Keap1 (Mus musculus) 6480464 Arsenic binds to KEAP1 protein CTD PMID:19808700 arsenite(3-) decreases expression EXP 6480464 arsenite results in decreased expression of KEAP1 mRNA and arsenite results in decreased expression of KEAP1 protein CTD PMID:22476201 arsenite(3-) affects response to substance EXP 6480464 KEAP1 protein affects the susceptibility to arsenite CTD PMID:22476201 arsenite(3-) multiple interactions EXP 6480464 epigallocatechin gallate promotes the reaction [arsenite results in increased expression of KEAP1 mRNA] more ... CTD PMID:22476201 and PMID:29572906 arsenite(3-) increases expression EXP 6480464 arsenite results in increased expression of KEAP1 mRNA and arsenite results in increased expression of KEAP1 protein CTD PMID:22476201 and PMID:29572906 arsenous acid decreases expression ISO Keap1 (Rattus norvegicus) 6480464 Arsenic Trioxide results in decreased expression of KEAP1 protein CTD PMID:24634002 and PMID:32920515 arsenous acid multiple interactions ISO Keap1 (Mus musculus) 6480464 18alpha and 20beta-hydroxy-11-oxo-norolean-12-en-3beta-yl-2-O-beta-D-glucopyranurosyl-alpha-D-glucopyranosiduronate magnesium tetrahydrate inhibits the reaction [Arsenic Trioxide results in increased expression of KEAP1 protein] CTD PMID:33846815 arsenous acid increases expression ISO Keap1 (Mus musculus) 6480464 Arsenic Trioxide results in increased expression of KEAP1 protein CTD PMID:33846815 arsenous acid multiple interactions ISO Keap1 (Rattus norvegicus) 6480464 crocin inhibits the reaction [Arsenic Trioxide results in decreased expression of KEAP1 protein] CTD PMID:32920515 arsenous acid affects response to substance EXP 6480464 KEAP1 gene mutant form affects the susceptibility to Arsenic Trioxide CTD PMID:30815697 arsenous acid increases response to substance EXP 6480464 KEAP1 mRNA results in increased susceptibility to Arsenic Trioxide CTD PMID:26708503 arsenous acid increases expression EXP 6480464 Arsenic Trioxide results in increased expression of KEAP1 mRNA and Arsenic Trioxide results in increased expression of KEAP1 protein CTD PMID:15894607 more ... arsenous acid decreases response to substance EXP 6480464 KEAP1 protein results in decreased susceptibility to Arsenic Trioxide CTD PMID:22684020 arsenous acid increases expression ISO Keap1 (Rattus norvegicus) 6480464 Arsenic Trioxide results in increased expression of KEAP1 mRNA CTD PMID:29223816 arsenous acid multiple interactions EXP 6480464 [Tretinoin co-treated with Arsenic Trioxide] results in increased expression of KEAP1 mRNA more ... CTD PMID:15894607 more ... atrazine decreases expression EXP 6480464 Atrazine results in decreased expression of KEAP1 mRNA CTD PMID:22378314 atrazine decreases expression ISO Keap1 (Rattus norvegicus) 6480464 Atrazine results in decreased expression of KEAP1 mRNA and Atrazine results in decreased expression of KEAP1 protein CTD PMID:34624533 atrazine decreases expression ISO Keap1 (Mus musculus) 6480464 Atrazine results in decreased expression of KEAP1 mRNA and Atrazine results in decreased expression of KEAP1 protein CTD PMID:30360616 more ... atrazine multiple interactions ISO Keap1 (Mus musculus) 6480464 Lycopene inhibits the reaction [Atrazine results in decreased expression of KEAP1 mRNA] and Lycopene inhibits the reaction [Atrazine results in decreased expression of KEAP1 protein] CTD PMID:30360616 and PMID:36216167 aureusidin decreases expression ISO Keap1 (Rattus norvegicus) 6480464 aureusidin results in decreased expression of KEAP1 mRNA and aureusidin results in decreased expression of KEAP1 protein CTD PMID:31790703 azathioprine affects response to substance ISO Keap1 (Mus musculus) 6480464 KEAP1 protein affects the susceptibility to Azathioprine CTD PMID:21803983 bafilomycin A1 multiple interactions EXP 6480464 bafilomycin A1 promotes the reaction [pachastrissamine analog promotes the reaction [KEAP1 protein binds to SQSTM1 protein]] CTD PMID:35123989 baicalin multiple interactions ISO Keap1 (Mus musculus) 6480464 baicalin inhibits the reaction [1-Methyl-4-phenyl-1 more ... CTD PMID:38016618 Bardoxolone methyl increases expression EXP 6480464 bardoxolone methyl results in increased expression of KEAP1 protein CTD PMID:27358234 Bardoxolone methyl decreases expression EXP 6480464 bardoxolone methyl results in decreased expression of KEAP1 mRNA CTD PMID:35724838 Bardoxolone methyl multiple interactions ISO Keap1 (Mus musculus) 6480464 bardoxolone methyl inhibits the reaction [aristolochic acid I results in increased expression of KEAP1 protein] CTD PMID:24530882 belinostat decreases expression EXP 6480464 belinostat results in decreased expression of KEAP1 mRNA CTD PMID:19606018 benzene decreases expression EXP 6480464 Benzene results in decreased expression of KEAP1 mRNA CTD PMID:33064461 benzene increases expression ISO Keap1 (Mus musculus) 6480464 Benzene results in increased expression of KEAP1 protein CTD PMID:36306860 benzene-1,2,4-triol increases expression EXP 6480464 hydroxyhydroquinone results in increased expression of KEAP1 mRNA CTD PMID:17572062 benzo[a]pyrene increases expression ISO Keap1 (Mus musculus) 6480464 Benzo(a)pyrene results in increased expression of KEAP1 mRNA CTD PMID:21569818 and PMID:22228805 benzo[a]pyrene decreases expression ISO Keap1 (Rattus norvegicus) 6480464 Benzo(a)pyrene results in decreased expression of KEAP1 protein CTD PMID:36736873 benzo[a]pyrene increases expression EXP 6480464 Benzo(a)pyrene results in increased expression of KEAP1 mRNA CTD PMID:20106945 more ... benzo[a]pyrene decreases expression EXP 6480464 Benzo(a)pyrene results in decreased expression of KEAP1 mRNA and Benzo(a)pyrene results in decreased expression of KEAP1 protein CTD PMID:20498004 and PMID:25946486 benzo[a]pyrene diol epoxide I decreases expression EXP 6480464 7 more ... CTD PMID:19150397 benzoquinones multiple interactions ISO Keap1 (Mus musculus) 6480464 Benzoquinones analog binds to and results in increased metabolism of KEAP1 protein CTD PMID:21651925 betulin multiple interactions ISO Keap1 (Rattus norvegicus) 6480464 betulin inhibits the reaction [9 more ... CTD PMID:33759307 bis(2-ethylhexyl) phthalate multiple interactions ISO Keap1 (Mus musculus) 6480464 Lycopene inhibits the reaction [Diethylhexyl Phthalate results in decreased expression of KEAP1 mRNA] more ... CTD PMID:35917956 and PMID:36610486 bis(2-ethylhexyl) phthalate increases expression ISO Keap1 (Mus musculus) 6480464 Diethylhexyl Phthalate results in increased expression of KEAP1 protein CTD PMID:36610486 bis(2-ethylhexyl) phthalate decreases expression ISO Keap1 (Mus musculus) 6480464 Diethylhexyl Phthalate results in decreased expression of KEAP1 mRNA and Diethylhexyl Phthalate results in decreased expression of KEAP1 protein CTD PMID:35917956 bisdemethoxycurcumin multiple interactions ISO Keap1 (Mus musculus) 6480464 KEAP1 protein inhibits the reaction [bisdemethoxycurcumin results in increased expression of HMOX1 mRNA] CTD PMID:17535857 bisphenol A affects expression ISO Keap1 (Rattus norvegicus) 6480464 bisphenol A affects the expression of KEAP1 mRNA CTD PMID:25181051 bisphenol A decreases expression ISO Keap1 (Rattus norvegicus) 6480464 bisphenol A analog results in decreased expression of KEAP1 mRNA and bisphenol A analog results in decreased expression of KEAP1 protein CTD PMID:35427877 bisphenol A increases expression ISO Keap1 (Mus musculus) 6480464 bisphenol A results in increased expression of KEAP1 mRNA CTD PMID:32156529 bisphenol A multiple interactions EXP 6480464 [[ginger extract results in increased abundance of Oils and Volatile] which co-treated with bisphenol A] affects the expression of KEAP1 protein CTD PMID:33376534 bisphenol A increases methylation ISO Keap1 (Rattus norvegicus) 6480464 bisphenol A results in increased methylation of KEAP1 gene CTD PMID:28505145 bleomycin A2 multiple interactions ISO Keap1 (Rattus norvegicus) 6480464 celastrol inhibits the reaction [Bleomycin results in decreased expression of KEAP1 protein] CTD PMID:26768587 bleomycin A2 decreases expression ISO Keap1 (Rattus norvegicus) 6480464 Bleomycin results in decreased expression of KEAP1 protein CTD PMID:26768587 bromosulfophthalein decreases glutathionylation ISO Keap1 (Mus musculus) 6480464 KEAP1 protein results in decreased glutathionylation of Sulfobromophthalein CTD PMID:19246623 bromosulfophthalein decreases transport ISO Keap1 (Mus musculus) 6480464 KEAP1 protein results in decreased transport of Sulfobromophthalein CTD PMID:19246623 Brusatol multiple interactions EXP 6480464 [KEAP1 protein results in decreased expression of NFE2L2 protein] which results in decreased susceptibility to brusatol more ... CTD PMID:21205897 and PMID:32682831 Brusatol multiple interactions ISO Keap1 (Rattus norvegicus) 6480464 brusatol inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of KEAP1 protein] CTD PMID:34695510 buspirone multiple interactions ISO Keap1 (Rattus norvegicus) 6480464 Buspirone inhibits the reaction [Methotrexate results in increased expression of KEAP1 mRNA] CTD PMID:37341015 C60 fullerene increases expression ISO Keap1 (Rattus norvegicus) 6480464 fullerene C60 results in increased expression of KEAP1 mRNA CTD PMID:19167457 cadmium atom increases degradation ISO Keap1 (Rattus norvegicus) 6480464 Cadmium results in increased degradation of KEAP1 protein CTD PMID:27658547 cadmium atom increases expression ISO Keap1 (Mus musculus) 6480464 Cadmium results in increased expression of KEAP1 mRNA CTD PMID:37270049 cadmium atom multiple interactions ISO Keap1 (Rattus norvegicus) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of KEAP1 mRNA more ... CTD PMID:34695510 and PMID:36718047 cadmium dichloride decreases expression ISO Keap1 (Mus musculus) 6480464 Cadmium Chloride results in decreased expression of KEAP1 mRNA CTD PMID:20061341 cadmium dichloride decreases expression EXP 6480464 Cadmium Chloride results in decreased expression of KEAP1 protein CTD PMID:35122928 cadmium dichloride decreases expression ISO Keap1 (Rattus norvegicus) 6480464 Cadmium Chloride results in decreased expression of KEAP1 protein CTD PMID:35122928 cadmium dichloride affects folding ISO Keap1 (Mus musculus) 6480464 Cadmium Chloride affects the folding of KEAP1 protein CTD PMID:30261176 cadmium dichloride multiple interactions ISO Keap1 (Rattus norvegicus) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of KEAP1 mRNA more ... CTD PMID:34695510 and PMID:36718047 cadmium dichloride affects binding ISO Keap1 (Mus musculus) 6480464 Cadmium Chloride binds to KEAP1 protein CTD PMID:19808700 and PMID:26827822 cadmium dichloride multiple interactions ISO Keap1 (Mus musculus) 6480464 [Cadmium Chloride affects the reaction [NFE2L2 protein binds to KEAP1 protein]] affects the localization of [NFE2L2 protein binds to KEAP1 protein] more ... CTD PMID:18512965 more ... carbendazim multiple interactions ISO Keap1 (Rattus norvegicus) 6480464 Chitosan inhibits the reaction [carbendazim results in increased expression of KEAP1 mRNA] CTD PMID:35705592 carbendazim increases expression ISO Keap1 (Rattus norvegicus) 6480464 carbendazim results in increased expression of KEAP1 mRNA CTD PMID:35705592 carbon disulfide decreases expression ISO Keap1 (Rattus norvegicus) 6480464 Carbon Disulfide results in decreased expression of KEAP1 protein CTD PMID:27530093 carbon monoxide multiple interactions ISO Keap1 (Mus musculus) 6480464 Carbon Monoxide inhibits the reaction [NFE2L2 protein binds to KEAP1 protein] CTD PMID:18845810 CCCP multiple interactions EXP 6480464 [[Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [SQSTM1 protein binds to KEAP1 protein]] promotes the reaction [KEAP1 protein binds to NFE2L2 protein]] which results in decreased activity of NFE2L2 protein more ... CTD PMID:30715550 celastrol multiple interactions ISO Keap1 (Rattus norvegicus) 6480464 celastrol inhibits the reaction [Bleomycin results in decreased expression of KEAP1 protein] CTD PMID:26768587 CGP 52608 multiple interactions EXP 6480464 CGP 52608 promotes the reaction [RORA protein binds to KEAP1 gene] CTD PMID:28238834 chalcones decreases expression ISO Keap1 (Rattus norvegicus) 6480464 Chalcones analog results in decreased expression of KEAP1 protein CTD PMID:23963778 CHIR 99021 multiple interactions EXP 6480464 [4-(2-(5 more ... CTD PMID:34480604 chitosan multiple interactions ISO Keap1 (Rattus norvegicus) 6480464 Chitosan inhibits the reaction [carbendazim results in increased expression of KEAP1 mRNA] CTD PMID:35705592 chlorambucil multiple interactions EXP 6480464 [KEAP1 gene mutant form results in increased activity of NFE2L2] which results in decreased susceptibility to Chlorambucil and Buthionine Sulfoximine inhibits the reaction [[KEAP1 gene mutant form results in increased activity of NFE2L2] which results in decreased susceptibility to Chlorambucil] CTD PMID:19608619 chloroacetaldehyde increases expression EXP 6480464 chloroacetaldehyde results in increased expression of KEAP1 mRNA CTD PMID:25596134 choline multiple interactions ISO Keap1 (Mus musculus) 6480464 KEAP1 affects the reaction [[Choline deficiency co-treated with Methionine deficiency] results in increased expression of CD36 mRNA] more ... CTD PMID:20350562 cidofovir anhydrous increases expression EXP 6480464 Cidofovir results in increased expression of KEAP1 mRNA CTD PMID:25596134 cisplatin multiple interactions EXP 6480464 [Cisplatin co-treated with jinfukang] results in increased expression of KEAP1 mRNA and [KEAP1 protein results in decreased stability of NFE2L2 protein] which results in increased susceptibility to Cisplatin CTD PMID:20530669 and PMID:27392435 cisplatin affects expression ISO Keap1 (Rattus norvegicus) 6480464 Cisplatin affects the expression of KEAP1 protein CTD PMID:30125553 cisplatin increases expression EXP 6480464 Cisplatin results in increased expression of KEAP1 mRNA CTD PMID:25596134 and PMID:27594783 cisplatin increases response to substance EXP 6480464 KEAP1 protein results in increased susceptibility to Cisplatin CTD PMID:25841332 Clivoline increases expression EXP 6480464 clivorine results in increased expression of KEAP1 mRNA CTD PMID:25881548 clodronic acid increases expression EXP 6480464 Clodronic Acid results in increased expression of KEAP1 mRNA CTD PMID:25596134 clofibric acid multiple interactions ISO Keap1 (Rattus norvegicus) 6480464 [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of KEAP1 mRNA CTD PMID:17602206 cobalt atom affects binding ISO Keap1 (Mus musculus) 6480464 Cobalt binds to KEAP1 protein CTD PMID:15865434 cobalt atom multiple interactions ISO Keap1 (Mus musculus) 6480464 Zinc inhibits the reaction [Cobalt binds to KEAP1 protein] CTD PMID:15865434 cobalt dichloride increases expression ISO Keap1 (Rattus norvegicus) 6480464 cobaltous chloride results in increased expression of KEAP1 mRNA CTD PMID:24386269 cobalt dichloride affects response to substance EXP 6480464 KEAP1 protein affects the susceptibility to cobaltous chloride CTD PMID:29966676 cobalt dichloride multiple interactions EXP 6480464 KEAP1 protein inhibits the reaction [cobaltous chloride results in increased expression of GCLC mRNA] more ... CTD PMID:29966676 colistin increases expression ISO Keap1 (Mus musculus) 6480464 Colistin results in increased expression of KEAP1 mRNA and Colistin results in increased expression of KEAP1 protein CTD PMID:34560125 copper atom multiple interactions EXP 6480464 [Chelating Agents binds to Copper] which affects the expression of KEAP1 mRNA and [Chelating Agents binds to Copper] which results in increased expression of KEAP1 mRNA CTD PMID:30911355 copper(0) multiple interactions EXP 6480464 [Chelating Agents binds to Copper] which affects the expression of KEAP1 mRNA and [Chelating Agents binds to Copper] which results in increased expression of KEAP1 mRNA CTD PMID:30911355 copper(II) sulfate multiple interactions ISO Keap1 (Mus musculus) 6480464 Acetylcysteine inhibits the reaction [Copper Sulfate results in decreased expression of KEAP1 mRNA] more ... CTD PMID:37353053 copper(II) sulfate decreases expression ISO Keap1 (Mus musculus) 6480464 Copper Sulfate results in decreased expression of KEAP1 mRNA and Copper Sulfate results in decreased expression of KEAP1 protein CTD PMID:37353053 cortisol multiple interactions EXP 6480464 [4-(2-(5 more ... CTD PMID:34480604 crocin-1 multiple interactions ISO Keap1 (Rattus norvegicus) 6480464 crocin inhibits the reaction [Arsenic Trioxide results in decreased expression of KEAP1 protein] CTD PMID:32920515 CU-O LINKAGE decreases expression EXP 6480464 cupric oxide results in decreased expression of KEAP1 mRNA CTD PMID:32285662 cumene hydroperoxide multiple interactions EXP 6480464 [KEAP1 gene mutant form results in increased activity of NFE2L2] which results in decreased susceptibility to cumene hydroperoxide and Buthionine Sulfoximine inhibits the reaction [[KEAP1 gene mutant form results in increased activity of NFE2L2] which results in decreased susceptibility to cumene hydroperoxide] CTD PMID:19608619 curcumin multiple interactions ISO Keap1 (Mus musculus) 6480464 Curcumin inhibits the reaction [Aflatoxin B1 results in decreased expression of KEAP1 mRNA] more ... CTD PMID:17535857 and PMID:35063475 curcumin multiple interactions EXP 6480464 Curcumin inhibits the reaction [Hydrogen Peroxide results in decreased expression of KEAP1 mRNA] and Curcumin inhibits the reaction [KEAP1 protein results in increased ubiquitination of NFE2L2 protein] CTD PMID:31521693 and PMID:34758851 curcumin decreases expression ISO Keap1 (Rattus norvegicus) 6480464 Curcumin analog results in decreased expression of KEAP1 protein and Curcumin results in decreased expression of KEAP1 protein CTD PMID:30946834 curcumin multiple interactions ISO Keap1 (Rattus norvegicus) 6480464 Curcumin analog promotes the reaction [APP protein modified form results in decreased expression of KEAP1 protein] more ... CTD PMID:30946834 and PMID:36037877 curcumin decreases expression EXP 6480464 Curcumin results in decreased expression of KEAP1 mRNA CTD PMID:31521693 curcumin increases expression EXP 6480464 Curcumin results in increased expression of KEAP1 mRNA CTD PMID:23710286 curcumin decreases expression ISO Keap1 (Mus musculus) 6480464 Curcumin analog results in decreased expression of KEAP1 protein CTD PMID:26991801 cyclophosphamide multiple interactions ISO Keap1 (Rattus norvegicus) 6480464 Quercetin inhibits the reaction [Cyclophosphamide results in decreased expression of KEAP1 mRNA] CTD PMID:37419146 cyclophosphamide decreases expression ISO Keap1 (Rattus norvegicus) 6480464 Cyclophosphamide results in decreased expression of KEAP1 mRNA CTD PMID:37419146 cyclosporin A increases expression EXP 6480464 Cyclosporine results in increased expression of KEAP1 mRNA CTD PMID:25596134 cyclosporin A decreases expression ISO Keap1 (Rattus norvegicus) 6480464 Cyclosporine results in decreased expression of KEAP1 mRNA CTD PMID:25596134 D-glucose multiple interactions ISO Keap1 (Mus musculus) 6480464 [NFE2L2 protein co-treated with KEAP1 protein] affects the abundance of Glucose CTD PMID:23017736 D-glucose increases expression EXP 6480464 Glucose results in increased expression of KEAP1 mRNA and Glucose results in increased expression of KEAP1 protein CTD PMID:37586544 D-glucose multiple interactions EXP 6480464 solanesol inhibits the reaction [Glucose results in increased expression of KEAP1 mRNA] and solanesol inhibits the reaction [Glucose results in increased expression of KEAP1 protein] CTD PMID:37586544 D-glucose multiple interactions ISO Keap1 (Rattus norvegicus) 6480464 [Oxygen deficiency co-treated with Glucose deficiency] results in decreased expression of KEAP1 protein more ... CTD PMID:35191607 decabromodiphenyl ether decreases expression EXP 6480464 decabromobiphenyl ether results in decreased expression of KEAP1 protein CTD PMID:33675858 decabromodiphenyl ether multiple interactions EXP 6480464 Luteolin inhibits the reaction [decabromobiphenyl ether results in decreased expression of KEAP1 protein] CTD PMID:33675858 decabromodiphenyl ether increases expression EXP 6480464 decabromobiphenyl ether results in increased expression of KEAP1 mRNA and decabromobiphenyl ether results in increased expression of KEAP1 protein CTD PMID:34571075 and PMID:35266255 deguelin increases expression EXP 6480464 deguelin results in increased expression of KEAP1 mRNA CTD PMID:33512557 demethoxycurcumin multiple interactions ISO Keap1 (Mus musculus) 6480464 KEAP1 protein inhibits the reaction [demethoxycurcumin results in increased expression of HMOX1 mRNA] CTD PMID:17535857 Dendrobine multiple interactions EXP 6480464 dendrobine inhibits the reaction [Hydrogen Peroxide results in increased expression of KEAP1 mRNA] more ... CTD PMID:36058301 deoxynivalenol decreases expression ISO Keap1 (Mus musculus) 6480464 deoxynivalenol results in decreased expression of KEAP1 mRNA CTD PMID:34400200 diallyl disulfide multiple interactions ISO Keap1 (Mus musculus) 6480464 diallyl disulfide promotes the reaction [lipopolysaccharide and Escherichia coli O111 B4 results in decreased expression of KEAP1 protein] CTD PMID:34896185 diallyl disulfide decreases expression ISO Keap1 (Mus musculus) 6480464 diallyl disulfide results in decreased expression of KEAP1 protein CTD PMID:34896185 diallyl trisulfide decreases expression ISO Keap1 (Rattus norvegicus) 6480464 diallyl trisulfide results in decreased expression of KEAP1 protein CTD PMID:23453443 diallyl trisulfide affects binding EXP 6480464 diallyl trisulfide binds to KEAP1 protein CTD PMID:24489685 diallyl trisulfide multiple interactions EXP 6480464 diallyl trisulfide promotes the reaction [KEAP1 mutant form affects the localization of NFE2L2 protein] CTD PMID:24489685 diarsenic trioxide multiple interactions ISO Keap1 (Rattus norvegicus) 6480464 crocin inhibits the reaction [Arsenic Trioxide results in decreased expression of KEAP1 protein] CTD PMID:32920515 diarsenic trioxide increases expression ISO Keap1 (Mus musculus) 6480464 Arsenic Trioxide results in increased expression of KEAP1 protein CTD PMID:33846815 diarsenic trioxide multiple interactions ISO Keap1 (Mus musculus) 6480464 18alpha and 20beta-hydroxy-11-oxo-norolean-12-en-3beta-yl-2-O-beta-D-glucopyranurosyl-alpha-D-glucopyranosiduronate magnesium tetrahydrate inhibits the reaction [Arsenic Trioxide results in increased expression of KEAP1 protein] CTD PMID:33846815 diarsenic trioxide increases expression ISO Keap1 (Rattus norvegicus) 6480464 Arsenic Trioxide results in increased expression of KEAP1 mRNA CTD PMID:29223816 diarsenic trioxide multiple interactions EXP 6480464 [Tretinoin co-treated with Arsenic Trioxide] results in increased expression of KEAP1 mRNA more ... CTD PMID:15894607 more ... diarsenic trioxide affects response to substance EXP 6480464 KEAP1 gene mutant form affects the susceptibility to Arsenic Trioxide CTD PMID:30815697 diarsenic trioxide decreases expression ISO Keap1 (Rattus norvegicus) 6480464 Arsenic Trioxide results in decreased expression of KEAP1 protein CTD PMID:24634002 and PMID:32920515 diarsenic trioxide increases response to substance EXP 6480464 KEAP1 mRNA results in increased susceptibility to Arsenic Trioxide CTD PMID:26708503 diarsenic trioxide decreases response to substance EXP 6480464 KEAP1 protein results in decreased susceptibility to Arsenic Trioxide CTD PMID:22684020 diarsenic trioxide increases expression EXP 6480464 Arsenic Trioxide results in increased expression of KEAP1 mRNA and Arsenic Trioxide results in increased expression of KEAP1 protein CTD PMID:15894607 more ... dibutyl phthalate decreases expression ISO Keap1 (Rattus norvegicus) 6480464 Dibutyl Phthalate results in decreased expression of KEAP1 mRNA CTD PMID:21266533 dibutyl phthalate decreases expression ISO Keap1 (Mus musculus) 6480464 Dibutyl Phthalate results in decreased expression of KEAP1 mRNA CTD PMID:17361019 dichloroacetyl chloride multiple interactions ISO Keap1 (Mus musculus) 6480464 2-tert-butylhydroquinone inhibits the reaction [2 more ... CTD PMID:32073640 dichloroacetyl chloride increases expression ISO Keap1 (Mus musculus) 6480464 2 more ... CTD PMID:32073640 diethyl maleate increases expression EXP 6480464 diethyl maleate results in increased expression of KEAP1 mRNA and diethyl maleate results in increased expression of KEAP1 protein CTD PMID:27358234 more ... diethyl phthalate increases expression ISO Keap1 (Mus musculus) 6480464 diethyl phthalate results in increased expression of KEAP1 protein CTD PMID:37942807 diethylstilbestrol increases expression ISO Keap1 (Rattus norvegicus) 6480464 Diethylstilbestrol results in increased expression of KEAP1 mRNA CTD PMID:37077353 dihydroartemisinin affects binding EXP 6480464 artenimol analog binds to KEAP1 protein CTD PMID:26340163 dimercaprol affects binding ISO Keap1 (Mus musculus) 6480464 Dimercaprol binds to KEAP1 protein CTD PMID:19808700 dioscin multiple interactions ISO Keap1 (Rattus norvegicus) 6480464 dioscin inhibits the reaction [Doxorubicin results in increased expression of KEAP1 protein] CTD PMID:28082111 diosmetin multiple interactions ISO Keap1 (Rattus norvegicus) 6480464 diosmetin promotes the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in decreased expression of KEAP1 protein] more ... CTD PMID:35191607 dioxygen decreases expression EXP 6480464 Oxygen deficiency results in decreased expression of KEAP1 mRNA and Oxygen deficiency results in decreased expression of KEAP1 protein CTD PMID:25596134 and PMID:34023435 dioxygen multiple interactions EXP 6480464 [Ozone co-treated with Oxygen] inhibits the reaction [KEAP1 protein results in increased degradation of NFE2L2 protein] and [Ozone co-treated with Oxygen] results in increased expression of KEAP1 protein CTD PMID:26270818 and PMID:29864481 dioxygen multiple interactions ISO Keap1 (Rattus norvegicus) 6480464 [Oxygen deficiency co-treated with Blood Glucose deficiency] results in decreased expression of KEAP1 protein more ... CTD PMID:29139225 and PMID:35191607 dioxygen increases expression ISO Keap1 (Rattus norvegicus) 6480464 Oxygen deficiency results in increased expression of KEAP1 protein CTD PMID:29139225 diquat multiple interactions ISO Keap1 (Mus musculus) 6480464 [KEAP1 gene mutant form inhibits the reaction [Diquat results in decreased abundance of Glutathione]] which results in increased expression of GCLC mRNA more ... CTD PMID:22762311 diquat decreases expression ISO Keap1 (Mus musculus) 6480464 Diquat results in decreased expression of KEAP1 protein CTD PMID:36851058 disodium selenite multiple interactions ISO Keap1 (Rattus norvegicus) 6480464 Sodium Selenite inhibits the reaction [Sodium Fluoride results in decreased expression of KEAP1 mRNA] CTD PMID:36736877 divanadium pentaoxide decreases expression EXP 6480464 vanadium pentoxide results in decreased expression of KEAP1 mRNA CTD PMID:17459161 dorsomorphin multiple interactions EXP 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 doxorubicin increases expression ISO Keap1 (Rattus norvegicus) 6480464 Doxorubicin results in increased expression of KEAP1 protein CTD PMID:28082111 and PMID:37030624 doxorubicin increases expression EXP 6480464 Doxorubicin results in increased expression of KEAP1 mRNA CTD PMID:29803840 doxorubicin multiple interactions ISO Keap1 (Mus musculus) 6480464 indole-3-carbinol inhibits the reaction [Doxorubicin results in increased expression of KEAP1 protein] and naringin inhibits the reaction [Doxorubicin results in decreased expression of KEAP1 protein] CTD PMID:29775573 and PMID:36811345 doxorubicin increases expression ISO Keap1 (Mus musculus) 6480464 Doxorubicin results in increased expression of KEAP1 protein CTD PMID:29775573 and PMID:36811345 doxorubicin multiple interactions ISO Keap1 (Rattus norvegicus) 6480464 dioscin inhibits the reaction [Doxorubicin results in increased expression of KEAP1 protein] and SIRT1 protein affects the reaction [Doxorubicin results in increased expression of KEAP1 protein] CTD PMID:28082111 and PMID:37030624 doxorubicin increases response to substance EXP 6480464 KEAP1 mRNA results in increased susceptibility to Doxorubicin CTD PMID:26708503 doxorubicin multiple interactions EXP 6480464 KEAP1 protein results in decreased export of and results in increased susceptibility to Doxorubicin CTD PMID:25841332 doxorubicin affects response to substance ISO Keap1 (Rattus norvegicus) 6480464 KEAP1 protein affects the susceptibility to Doxorubicin CTD PMID:24211725 doxorubicin increases degradation ISO Keap1 (Rattus norvegicus) 6480464 Doxorubicin results in increased degradation of KEAP1 protein CTD PMID:24211725 doxorubicin decreases expression ISO Keap1 (Rattus norvegicus) 6480464 Doxorubicin results in decreased expression of KEAP1 protein CTD PMID:24211725 doxorubicin decreases response to substance EXP 6480464 KEAP1 protein results in decreased susceptibility to Doxorubicin CTD PMID:22684020 elemental selenium increases expression EXP 6480464 Selenium results in increased expression of KEAP1 mRNA CTD PMID:19244175 ethanol multiple interactions ISO Keap1 (Mus musculus) 6480464 [dihydromyricetin co-treated with Ethanol] results in decreased expression of KEAP1 protein CTD PMID:28419832 ethanol affects splicing ISO Keap1 (Mus musculus) 6480464 Ethanol affects the splicing of KEAP1 mRNA CTD PMID:30319688 ethionamide multiple interactions EXP 6480464 KEAP1 mRNA inhibits the reaction [Ethionamide results in increased susceptibility to arsenic trioxide] CTD PMID:26708503 ethylene glycol bis(2-aminoethyl)tetraacetic acid multiple interactions ISO Keap1 (Mus musculus) 6480464 Egtazic Acid promotes the reaction [dexamethasone 21-methanesulfonate binds to KEAP1 protein] CTD PMID:15865434 ethylenediaminetetraacetic acid multiple interactions ISO Keap1 (Mus musculus) 6480464 Edetic Acid promotes the reaction [dexamethasone 21-methanesulfonate binds to KEAP1 protein] CTD PMID:15865434 etoposide decreases response to substance EXP 6480464 KEAP1 protein results in decreased susceptibility to Etoposide CTD PMID:22684020 etoposide multiple interactions EXP 6480464 KEAP1 protein affects the reaction [Etoposide results in increased expression of CDKN1A protein] CTD PMID:27982581 etoposide increases response to substance EXP 6480464 KEAP1 mRNA results in increased susceptibility to Etoposide CTD PMID:26708503 falcarindiol multiple interactions ISO Keap1 (Rattus norvegicus) 6480464 falcarindiol binds to and results in increased alkylation of KEAP1 protein more ... CTD PMID:20026152 falcarindiol affects folding ISO Keap1 (Rattus norvegicus) 6480464 falcarindiol affects the folding of KEAP1 protein CTD PMID:20026152 falcarindiol decreases activity ISO Keap1 (Rattus norvegicus) 6480464 falcarindiol results in decreased activity of KEAP1 protein CTD PMID:20026152 farrerol decreases expression ISO Keap1 (Mus musculus) 6480464 farrerol results in decreased expression of KEAP1 protein CTD PMID:26111761 fenofibrate multiple interactions ISO Keap1 (Mus musculus) 6480464 Fenofibrate inhibits the reaction [tyloxapol results in increased expression of KEAP1 protein] CTD PMID:36905866 finasteride increases expression ISO Keap1 (Rattus norvegicus) 6480464 Finasteride results in increased expression of KEAP1 mRNA CTD PMID:24136188 flavonoids decreases expression ISO Keap1 (Rattus norvegicus) 6480464 Flavonoids results in decreased expression of KEAP1 mRNA CTD PMID:18035473 flutamide increases expression ISO Keap1 (Rattus norvegicus) 6480464 Flutamide results in increased expression of KEAP1 mRNA CTD PMID:24136188 folic acid multiple interactions ISO Keap1 (Mus musculus) 6480464 [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of KEAP1 mRNA CTD PMID:22206623 fumonisin B1 decreases expression EXP 6480464 fumonisin B1 results in decreased expression of KEAP1 mRNA and fumonisin B1 results in decreased expression of KEAP1 protein CTD PMID:33496827 fumonisin B1 decreases expression ISO Keap1 (Mus musculus) 6480464 fumonisin B1 results in decreased expression of KEAP1 mRNA CTD PMID:35697133 fumonisin B1 multiple interactions EXP 6480464 [fumonisin B1 results in increased methylation of KEAP1 promoter] which results in decreased expression of KEAP1 mRNA CTD PMID:33496827 fumonisin B1 increases methylation EXP 6480464 fumonisin B1 results in increased methylation of KEAP1 promoter CTD PMID:33496827 galactose multiple interactions ISO Keap1 (Mus musculus) 6480464 albicanol inhibits the reaction [Galactose results in increased expression of KEAP1 mRNA] and albicanol inhibits the reaction [Galactose results in increased expression of KEAP1 protein] CTD PMID:33761044 galactose increases expression ISO Keap1 (Mus musculus) 6480464 Galactose results in increased expression of KEAP1 mRNA and Galactose results in increased expression of KEAP1 protein CTD PMID:33761044 gefitinib increases expression EXP 6480464 gefitinib results in increased expression of KEAP1 mRNA CTD PMID:27639429 gentamycin decreases expression ISO Keap1 (Rattus norvegicus) 6480464 Gentamicins results in decreased expression of KEAP1 mRNA CTD PMID:33387578 ginsenoside Rg1 multiple interactions ISO Keap1 (Mus musculus) 6480464 ginsenoside Rg1 inhibits the reaction [Carbon Tetrachloride results in increased expression of KEAP1 protein] CTD PMID:29964319 gliclazide multiple interactions ISO Keap1 (Rattus norvegicus) 6480464 Gliclazide inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of KEAP1 mRNA] and Gliclazide inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of KEAP1 protein] CTD PMID:21439372 glucose multiple interactions ISO Keap1 (Mus musculus) 6480464 [NFE2L2 protein co-treated with KEAP1 protein] affects the abundance of Glucose CTD PMID:23017736 glucose increases expression EXP 6480464 Glucose results in increased expression of KEAP1 mRNA and Glucose results in increased expression of KEAP1 protein CTD PMID:37586544 glucose multiple interactions ISO Keap1 (Rattus norvegicus) 6480464 [Oxygen deficiency co-treated with Glucose deficiency] results in decreased expression of KEAP1 protein more ... CTD PMID:35191607 glucose multiple interactions EXP 6480464 solanesol inhibits the reaction [Glucose results in increased expression of KEAP1 mRNA] and solanesol inhibits the reaction [Glucose results in increased expression of KEAP1 protein] CTD PMID:37586544 glutathione multiple interactions EXP 6480464 [KEAP1 gene mutant form results in increased activity of NFE2L2] which results in increased abundance of Glutathione more ... CTD PMID:19608619 and PMID:21972102 glutathione increases abundance ISO Keap1 (Mus musculus) 6480464 KEAP1 gene mutant form results in increased abundance of Glutathione CTD PMID:26827822 glutathione multiple interactions ISO Keap1 (Rattus norvegicus) 6480464 Glutathione inhibits the reaction [falcarindiol binds to and results in increased alkylation of KEAP1 protein] CTD PMID:20026152 glutathione multiple interactions ISO Keap1 (Mus musculus) 6480464 [KEAP1 gene mutant form inhibits the reaction [Diquat results in decreased abundance of Glutathione]] which results in increased expression of GCLC mRNA more ... CTD PMID:20800667 more ... glyburide multiple interactions ISO Keap1 (Rattus norvegicus) 6480464 Glyburide inhibits the reaction [Streptozocin results in decreased expression of KEAP1 mRNA] CTD PMID:30817903 glyphosate increases expression EXP 6480464 Glyphosate results in increased expression of KEAP1 mRNA CTD PMID:36625791 hemin decreases expression ISO Keap1 (Mus musculus) 6480464 Hemin results in decreased expression of KEAP1 protein CTD PMID:27777014 hesperetin affects binding EXP 6480464 hesperetin binds to KEAP1 protein CTD PMID:37487865 hexadecanoic acid multiple interactions EXP 6480464 [Palmitic Acid co-treated with Oleic Acid] results in increased expression of KEAP1 protein and Escin inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of KEAP1 protein] CTD PMID:36905866 hexaflumuron decreases expression ISO Keap1 (Rattus norvegicus) 6480464 hexafluoron results in decreased expression of KEAP1 mRNA CTD PMID:34993831 homocysteine increases expression EXP 6480464 Homocysteine results in increased expression of KEAP1 protein CTD PMID:22964297 hydrogen peroxide multiple interactions ISO Keap1 (Mus musculus) 6480464 Hydrogen Peroxide promotes the reaction [4-(2-pyridylazo)resorcinol inhibits the reaction [Zinc binds to KEAP1 protein]] CTD PMID:15865434 hydrogen peroxide increases expression ISO Keap1 (Rattus norvegicus) 6480464 Hydrogen Peroxide results in increased expression of KEAP1 protein CTD PMID:30104959 hydrogen peroxide decreases expression ISO Keap1 (Rattus norvegicus) 6480464 Hydrogen Peroxide results in decreased expression of KEAP1 protein CTD PMID:32275923 hydrogen peroxide multiple interactions ISO Keap1 (Rattus norvegicus) 6480464 Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of KEAP1 protein] more ... CTD PMID:30104959 and PMID:32275923 hydrogen peroxide increases expression EXP 6480464 Hydrogen Peroxide results in increased expression of KEAP1 mRNA and Hydrogen Peroxide results in increased expression of KEAP1 protein CTD PMID:31705858 and PMID:36058301 hydrogen peroxide multiple interactions EXP 6480464 4-((alpha-L-rhamnosyloxy)benzyl)isothiocyanate inhibits the reaction [Hydrogen Peroxide results in decreased expression of KEAP1 mRNA] more ... CTD PMID:25742418 more ... hydrogen peroxide decreases expression EXP 6480464 Hydrogen Peroxide results in decreased expression of KEAP1 mRNA and Hydrogen Peroxide results in decreased expression of KEAP1 protein CTD PMID:23410634 more ... hydrogen sulfide multiple interactions ISO Keap1 (Rattus norvegicus) 6480464 [sodium bisulfide results in increased abundance of Hydrogen Sulfide] inhibits the reaction [Paraquat promotes the reaction [KEAP1 protein binds to NFE2L2 protein]] and [sodium bisulfide results in increased abundance of Hydrogen Sulfide] inhibits the reaction [Paraquat results in increased expression of KEAP1 protein] CTD PMID:32064027 hydroquinone decreases expression ISO Keap1 (Mus musculus) 6480464 hydroquinone results in decreased expression of KEAP1 protein CTD PMID:23290930 hydroquinone decreases expression EXP 6480464 hydroquinone results in decreased expression of KEAP1 protein CTD PMID:36646296 hypochlorous acid increases expression ISO Keap1 (Mus musculus) 6480464 Hypochlorous Acid results in increased expression of KEAP1 mRNA CTD PMID:17980396 ifosfamide increases expression EXP 6480464 Ifosfamide results in increased expression of KEAP1 mRNA CTD PMID:25596134 imidacloprid decreases expression ISO Keap1 (Rattus norvegicus) 6480464 imidacloprid results in decreased expression of KEAP1 mRNA CTD PMID:34993831 indole-3-methanol multiple interactions ISO Keap1 (Mus musculus) 6480464 indole-3-carbinol inhibits the reaction [Doxorubicin results in increased expression of KEAP1 protein] CTD PMID:29775573 indometacin multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [Indomethacin inhibits the reaction [KEAP1 protein binds to NFE2L2 protein]] more ... CTD PMID:11909699 iron(III) citrate multiple interactions EXP 6480464 [trigonelline co-treated with ferric citrate] results in decreased expression of KEAP1 mRNA CTD PMID:29959986 isoniazide decreases expression ISO Keap1 (Mus musculus) 6480464 Isoniazid results in decreased expression of KEAP1 mRNA CTD PMID:33771660 isoprenaline multiple interactions ISO Keap1 (Rattus norvegicus) 6480464 [Isoproterenol co-treated with POSTN protein] results in decreased expression of KEAP1 mRNA more ... CTD PMID:30303030 and PMID:35430261 isoprenaline increases expression ISO Keap1 (Rattus norvegicus) 6480464 Isoproterenol results in increased expression of KEAP1 mRNA and Isoproterenol results in increased expression of KEAP1 protein CTD PMID:35430261 isoprenaline decreases expression ISO Keap1 (Rattus norvegicus) 6480464 Isoproterenol results in decreased expression of KEAP1 mRNA CTD PMID:30303030 ketoconazole increases expression ISO Keap1 (Rattus norvegicus) 6480464 Ketoconazole results in increased expression of KEAP1 mRNA CTD PMID:37077353 L-ascorbic acid multiple interactions EXP 6480464 [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of KEAP1 mRNA more ... CTD PMID:28285367 more ... L-ascorbic acid decreases expression EXP 6480464 Ascorbic Acid results in decreased expression of KEAP1 protein CTD PMID:31610155 L-ascorbic acid 2-phosphate multiple interactions EXP 6480464 [[ascorbate-2-phosphate co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of KEAP1 mRNA CTD PMID:34480604 L-methionine multiple interactions ISO Keap1 (Mus musculus) 6480464 KEAP1 affects the reaction [[Choline deficiency co-treated with Methionine deficiency] results in increased expression of CD36 mRNA] more ... CTD PMID:20350562 lansoprazole increases oxidation ISO Keap1 (Rattus norvegicus) 6480464 Lansoprazole results in increased oxidation of KEAP1 protein CTD PMID:19628634 lead diacetate multiple interactions EXP 6480464 [lead acetate results in increased abundance of Lead] which results in increased expression of KEAP1 protein more ... CTD PMID:31610155 lead diacetate decreases expression ISO Keap1 (Rattus norvegicus) 6480464 lead acetate results in decreased expression of KEAP1 mRNA CTD PMID:33862172 lead(0) multiple interactions EXP 6480464 [lead acetate results in increased abundance of Lead] which results in increased expression of KEAP1 protein more ... CTD PMID:31610155 leflunomide increases expression ISO Keap1 (Rattus norvegicus) 6480464 leflunomide results in increased expression of KEAP1 mRNA CTD PMID:24136188 linsidomine affects response to substance EXP 6480464 KEAP1 mRNA affects the susceptibility to linsidomine CTD PMID:16092930 lipoic acid increases expression EXP 6480464 Thioctic Acid results in increased expression of KEAP1 protein CTD PMID:19033392 lipoic acid multiple interactions ISO Keap1 (Mus musculus) 6480464 Thioctic Acid inhibits the reaction [Silicon results in increased expression of KEAP1 protein] CTD PMID:34252510 lipopolysaccharide multiple interactions ISO Keap1 (Mus musculus) 6480464 8-oxoberberine promotes the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased degradation of KEAP1 protein] more ... CTD PMID:35691465 liproxstatin-1 increases expression EXP 6480464 liproxstatin-1 results in increased expression of KEAP1 protein CTD PMID:37507096 liquiritin multiple interactions ISO Keap1 (Mus musculus) 6480464 liquiritin promotes the reaction [1-Naphthylisothiocyanate results in decreased expression of KEAP1 protein] CTD PMID:36008890 luteolin multiple interactions EXP 6480464 Luteolin inhibits the reaction [decabromobiphenyl ether results in decreased expression of KEAP1 protein] CTD PMID:33675858 lycopene multiple interactions ISO Keap1 (Mus musculus) 6480464 Lycopene inhibits the reaction [Atrazine results in decreased expression of KEAP1 mRNA] more ... CTD PMID:30360616 more ... lycopene increases expression ISO Keap1 (Mus musculus) 6480464 Lycopene results in increased expression of KEAP1 mRNA CTD PMID:36216167 manganese(II) chloride affects expression ISO Keap1 (Mus musculus) 6480464 manganese chloride affects the expression of KEAP1 protein CTD PMID:25288107 manganese(II) chloride multiple interactions ISO Keap1 (Mus musculus) 6480464 Melatonin affects the reaction [manganese chloride affects the expression of KEAP1 protein] CTD PMID:25288107 melatonin decreases expression ISO Keap1 (Mus musculus) 6480464 Melatonin results in decreased expression of KEAP1 protein CTD PMID:25288107 melatonin multiple interactions ISO Keap1 (Mus musculus) 6480464 Melatonin affects the reaction [manganese chloride affects the expression of KEAP1 protein] CTD PMID:25288107 menadione multiple interactions EXP 6480464 [KEAP1 gene mutant form results in increased activity of NFE2L2] which results in decreased susceptibility to Vitamin K 3 CTD PMID:19608619 menadione decreases expression EXP 6480464 Vitamin K 3 results in decreased expression of KEAP1 mRNA CTD PMID:23410634 mercury dibromide increases expression EXP 6480464 mercuric bromide results in increased expression of KEAP1 mRNA CTD PMID:26272509 mercury dibromide multiple interactions EXP 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of KEAP1 mRNA CTD PMID:27188386 metformin multiple interactions ISO Keap1 (Rattus norvegicus) 6480464 Metformin inhibits the reaction [Streptozocin results in increased expression of KEAP1 mRNA] and Metformin inhibits the reaction [Streptozocin results in increased expression of KEAP1 protein] CTD PMID:33639173 metformin multiple interactions ISO Keap1 (Mus musculus) 6480464 Metformin promotes the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of KEAP1 mRNA] CTD PMID:37120126 metformin decreases expression ISO Keap1 (Rattus norvegicus) 6480464 Metformin results in decreased expression of KEAP1 mRNA CTD PMID:25596134 methotrexate multiple interactions ISO Keap1 (Rattus norvegicus) 6480464 Buspirone inhibits the reaction [Methotrexate results in increased expression of KEAP1 mRNA] CTD PMID:37341015 methotrexate increases expression ISO Keap1 (Rattus norvegicus) 6480464 Methotrexate results in increased expression of KEAP1 mRNA CTD PMID:37341015 microcystin-LR affects binding EXP 6480464 cyanoginosin LR binds to KEAP1 protein CTD PMID:20722399 monascin multiple interactions EXP 6480464 monascin inhibits the reaction [S100B protein results in increased expression of KEAP1 protein] CTD PMID:23331247 N'-(2,4-dimethylphenyl)-N-methylformamidine increases expression ISO Keap1 (Rattus norvegicus) 6480464 U 40481 results in increased expression of KEAP1 protein CTD PMID:31029719 N'-(2,4-dimethylphenyl)-N-methylformamidine multiple interactions ISO Keap1 (Rattus norvegicus) 6480464 KEAP1 protein affects the reaction [U 40481 results in decreased expression of CAT protein] more ... CTD PMID:31029719 N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine multiple interactions ISO Keap1 (Mus musculus) 6480464 N more ... CTD PMID:15865434 N-acetyl-1,4-benzoquinone imine multiple interactions ISO Keap1 (Mus musculus) 6480464 KEAP1 protein inhibits the reaction [NQO1 protein results in increased metabolism of N-acetyl-4-benzoquinoneimine] CTD PMID:19246624 N-acetyl-1,4-benzoquinone imine affects metabolic processing ISO Keap1 (Mus musculus) 6480464 N-acetyl-4-benzoquinoneimine affects the metabolism of KEAP1 protein CTD PMID:18785192 N-acetyl-L-cysteine multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [Dinitrochlorobenzene results in increased expression of KEAP1 protein] and Acetylcysteine inhibits the reaction [Indomethacin inhibits the reaction [KEAP1 protein binds to NFE2L2 protein]] CTD PMID:11909699 and PMID:19033392 N-acetyl-L-cysteine multiple interactions ISO Keap1 (Mus musculus) 6480464 Acetylcysteine inhibits the reaction [Copper Sulfate results in decreased expression of KEAP1 mRNA] more ... CTD PMID:37353053 and PMID:37369159 N-acetyl-L-cysteine multiple interactions ISO Keap1 (Rattus norvegicus) 6480464 Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of KEAP1 protein] CTD PMID:30104959 N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal multiple interactions ISO Keap1 (Mus musculus) 6480464 [2-tert-butylhydroquinone co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] promotes the reaction [NFE2L2 protein binds to KEAP1 protein] and benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [NFE2L2 protein binds to KEAP1 protein] CTD PMID:18512965 N-methyl-4-phenylpyridinium multiple interactions ISO Keap1 (Mus musculus) 6480464 [1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in decreased expression of KEAP1 protein and baicalin promotes the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in decreased expression of KEAP1 protein] CTD PMID:38016618 N-methylnicotinate multiple interactions EXP 6480464 [trigonelline co-treated with ferric citrate] results in decreased expression of KEAP1 mRNA CTD PMID:29959986 N-nitrosodiethylamine multiple interactions ISO Keap1 (Rattus norvegicus) 6480464 [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of KEAP1 mRNA CTD PMID:17602206 NADP zwitterion affects abundance ISO Keap1 (Mus musculus) 6480464 KEAP1 protein affects the abundance of NADP CTD PMID:21775727 NADP(+) affects abundance ISO Keap1 (Mus musculus) 6480464 KEAP1 protein affects the abundance of NADP CTD PMID:21775727 naphthalene-1,2-diol increases metabolic processing ISO Keap1 (Mus musculus) 6480464 1 and 2-dihydroxynaphthalene analog results in increased metabolism of KEAP1 protein CTD PMID:25807370 naphthalene-1,2-diol multiple interactions ISO Keap1 (Mus musculus) 6480464 Glutathione inhibits the reaction [1 and 2-dihydroxynaphthalene analog results in increased metabolism of KEAP1 protein] CTD PMID:25807370 naringin multiple interactions ISO Keap1 (Mus musculus) 6480464 naringin inhibits the reaction [Doxorubicin results in decreased expression of KEAP1 protein] CTD PMID:36811345 nefazodone increases expression ISO Keap1 (Rattus norvegicus) 6480464 nefazodone results in increased expression of KEAP1 mRNA CTD PMID:24136188 nickel atom increases expression EXP 6480464 Nickel results in increased expression of KEAP1 protein CTD PMID:19033392 nicotinamide multiple interactions ISO Keap1 (Rattus norvegicus) 6480464 [Streptozocin co-treated with Niacinamide] results in increased expression of KEAP1 mRNA more ... CTD PMID:21439372 nicotinamide multiple interactions ISO Keap1 (Mus musculus) 6480464 2 more ... CTD PMID:37120126 ochratoxin A decreases expression EXP 6480464 ochratoxin A results in decreased expression of KEAP1 mRNA CTD PMID:32905824 oleic acid multiple interactions EXP 6480464 [Palmitic Acid co-treated with Oleic Acid] results in increased expression of KEAP1 protein and Escin inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of KEAP1 protein] CTD PMID:36905866 oxidopamine affects response to substance EXP 6480464 KEAP1 mRNA affects the susceptibility to Oxidopamine CTD PMID:16092930 ozone multiple interactions EXP 6480464 [Ozone co-treated with Oxygen] inhibits the reaction [KEAP1 protein results in increased degradation of NFE2L2 protein] and [Ozone co-treated with Oxygen] results in increased expression of KEAP1 protein CTD PMID:26270818 and PMID:29864481 ozone increases expression ISO Keap1 (Mus musculus) 6480464 [Ozone results in increased expression of HIF1A] which results in increased expression of KEAP1 CTD PMID:24040961 p-chloromercuribenzoic acid increases expression EXP 6480464 p-Chloromercuribenzoic Acid results in increased expression of KEAP1 mRNA CTD PMID:26272509 p-chloromercuribenzoic acid multiple interactions EXP 6480464 [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of KEAP1 mRNA CTD PMID:27188386 paclitaxel multiple interactions EXP 6480464 [KEAP1 protein results in decreased stability of NFE2L2 protein] which results in increased susceptibility to Paclitaxel CTD PMID:20530669 paracetamol increases expression EXP 6480464 Acetaminophen results in increased expression of KEAP1 mRNA CTD PMID:25881548 paracetamol decreases expression ISO Keap1 (Rattus norvegicus) 6480464 Acetaminophen results in decreased expression of KEAP1 mRNA CTD PMID:33387578 paracetamol affects expression ISO Keap1 (Mus musculus) 6480464 Acetaminophen affects the expression of KEAP1 protein CTD PMID:29331651 paracetamol decreases response to substance ISO Keap1 (Mus musculus) 6480464 KEAP1 gene mutant form results in decreased susceptibility to Acetaminophen CTD PMID:16293230 and PMID:25499718 paracetamol decreases expression EXP 6480464 Acetaminophen results in decreased expression of KEAP1 mRNA CTD PMID:21420995 paracetamol increases response to substance ISO Keap1 (Mus musculus) 6480464 KEAP1 results in increased susceptibility to Acetaminophen CTD PMID:20404090 paracetamol affects sulfation ISO Keap1 (Mus musculus) 6480464 KEAP1 protein affects the sulfation of Acetaminophen CTD PMID:19246624 paracetamol affects glucuronidation ISO Keap1 (Mus musculus) 6480464 KEAP1 protein affects the glucuronidation of Acetaminophen CTD PMID:19246624 paracetamol multiple interactions ISO Keap1 (Mus musculus) 6480464 ABCC3 protein affects the reaction [KEAP1 protein affects the glucuronidation of Acetaminophen] CTD PMID:19246624 paracetamol affects glutathionylation ISO Keap1 (Mus musculus) 6480464 KEAP1 protein affects the glutathionylation of Acetaminophen CTD PMID:19246624 paraquat multiple interactions ISO Keap1 (Rattus norvegicus) 6480464 [sodium bisulfide results in increased abundance of Hydrogen Sulfide] inhibits the reaction [Paraquat promotes the reaction [KEAP1 protein binds to NFE2L2 protein]] more ... CTD PMID:32064027 paraquat decreases expression EXP 6480464 Paraquat results in decreased expression of KEAP1 protein CTD PMID:37507096 paraquat increases expression ISO Keap1 (Rattus norvegicus) 6480464 Paraquat results in increased expression of KEAP1 protein CTD PMID:32064027 pentachlorophenol increases expression ISO Keap1 (Mus musculus) 6480464 Pentachlorophenol results in increased expression of KEAP1 mRNA CTD PMID:23892564 perfluorohexanesulfonic acid decreases expression ISO Keap1 (Mus musculus) 6480464 perfluorohexanesulfonic acid results in decreased expression of KEAP1 mRNA CTD PMID:37995155 perfluorooctane-1-sulfonic acid decreases expression ISO Keap1 (Rattus norvegicus) 6480464 perfluorooctane sulfonic acid results in decreased expression of KEAP1 mRNA CTD PMID:20621739 perillyl aldehyde multiple interactions EXP 6480464 KEAP1 protein inhibits the reaction [perillaldehyde results in increased expression of TXN mRNA] CTD PMID:19123792 phalloidin multiple interactions ISO Keap1 (Mus musculus) 6480464 [KEAP1 gene mutant form results in decreased susceptibility to Phalloidine] which results in decreased expression of CXCL1 mRNA more ... CTD PMID:25280775 phalloidin decreases response to substance ISO Keap1 (Mus musculus) 6480464 KEAP1 gene mutant form results in decreased susceptibility to Phalloidine CTD PMID:25280775 phenobarbital multiple interactions ISO Keap1 (Mus musculus) 6480464 KEAP1 protein affects the reaction [Phenobarbital results in increased expression of CYP2A5 mRNA] CTD PMID:22859313 phenylarsine oxide affects binding ISO Keap1 (Mus musculus) 6480464 oxophenylarsine binds to KEAP1 protein CTD PMID:19786557 and PMID:19808700 phenylmercury acetate increases expression EXP 6480464 Phenylmercuric Acetate results in increased expression of KEAP1 mRNA CTD PMID:26272509 phenylmercury acetate multiple interactions EXP 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of KEAP1 mRNA CTD PMID:27188386 phlorizin increases expression ISO Keap1 (Mus musculus) 6480464 Phlorhizin results in increased expression of KEAP1 mRNA CTD PMID:22538082 pirinixic acid multiple interactions EXP 6480464 [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of KEAP1 mRNA CTD PMID:19710929 porphyrins increases expression EXP 6480464 Porphyrins results in increased expression of KEAP1 mRNA CTD PMID:31385236 potassium dichromate multiple interactions ISO Keap1 (Mus musculus) 6480464 Potassium Dichromate affects the localization of and results in decreased ubiquitination of KEAP1 protein and Potassium Dichromate inhibits the reaction [NFE2L2 protein binds to KEAP1 protein] CTD PMID:17420218 pterostilbene multiple interactions ISO Keap1 (Mus musculus) 6480464 pterostilbene inhibits the reaction [NFE2L2 protein binds to KEAP1 protein] CTD PMID:26700463 quercetin multiple interactions EXP 6480464 Quercetin inhibits the reaction [tert-Butylhydroperoxide results in increased expression of KEAP1 protein] and Quercetin results in increased metabolism of and results in increased degradation of and results in decreased expression of KEAP1 protein CTD PMID:17462537 and PMID:27050144 quercetin multiple interactions ISO Keap1 (Rattus norvegicus) 6480464 Quercetin inhibits the reaction [Cyclophosphamide results in decreased expression of KEAP1 mRNA] CTD PMID:37419146 quercetin decreases expression ISO Keap1 (Rattus norvegicus) 6480464 Quercetin results in decreased expression of KEAP1 protein CTD PMID:25339115 quercetin increases expression ISO Keap1 (Mus musculus) 6480464 Quercetin results in increased expression of KEAP1 mRNA CTD PMID:23295412 quercetin 3-O-beta-D-glucofuranoside multiple interactions ISO Keap1 (Rattus norvegicus) 6480464 isoquercitrin inhibits the reaction [Streptozocin results in decreased expression of KEAP1 mRNA] CTD PMID:30817903 quercetin 3-O-beta-D-glucopyranoside multiple interactions ISO Keap1 (Rattus norvegicus) 6480464 isoquercitrin inhibits the reaction [Streptozocin results in decreased expression of KEAP1 mRNA] CTD PMID:30817903 quercitrin increases expression EXP 6480464 quercitrin results in increased expression of KEAP1 mRNA CTD PMID:25193878 quinolinic acid multiple interactions ISO Keap1 (Rattus norvegicus) 6480464 Quinolinic Acid promotes the reaction [DPP3 protein binds to KEAP1 protein] more ... CTD PMID:30876764 reactive oxygen species increases expression EXP 6480464 Reactive Oxygen Species results in increased expression of KEAP1 mRNA CTD PMID:25800948 resveratrol multiple interactions ISO Keap1 (Rattus norvegicus) 6480464 resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of KEAP1 mRNA] more ... CTD PMID:21439372 and PMID:23551926 resveratrol multiple interactions ISO Keap1 (Mus musculus) 6480464 Resveratrol inhibits the reaction [Rotenone results in increased expression of KEAP1 protein] CTD PMID:34391968 resveratrol multiple interactions EXP 6480464 [Resveratrol co-treated with Plant Extracts] inhibits the reaction [[Dietary Fats co-treated with Dietary Carbohydrates] results in increased expression of KEAP1 protein] more ... CTD PMID:16948474 more ... rosmarinic acid decreases expression EXP 6480464 Rosmarinic Acid results in decreased expression of KEAP1 protein CTD PMID:31610155 rosmarinic acid multiple interactions EXP 6480464 Rosmarinic Acid inhibits the reaction [[lead acetate results in increased abundance of Lead] which results in increased expression of KEAP1 protein] CTD PMID:31610155 rotenone decreases response to substance ISO Keap1 (Mus musculus) 6480464 KEAP1 gene mutant form results in decreased susceptibility to Rotenone CTD PMID:19167360 rotenone multiple interactions ISO Keap1 (Mus musculus) 6480464 Resveratrol inhibits the reaction [Rotenone results in increased expression of KEAP1 protein] CTD PMID:34391968 rotenone increases expression ISO Keap1 (Mus musculus) 6480464 Rotenone results in increased expression of KEAP1 protein CTD PMID:34391968 and PMID:35919817 rotenone decreases expression ISO Keap1 (Mus musculus) 6480464 Rotenone results in decreased expression of KEAP1 mRNA CTD PMID:23186747 S-butyl-DL-homocysteine (S,R)-sulfoximine multiple interactions EXP 6480464 Buthionine Sulfoximine inhibits the reaction [[KEAP1 gene mutant form results in increased activity of NFE2L2] which results in decreased susceptibility to Acrolein] more ... CTD PMID:19608619 SB 431542 multiple interactions EXP 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 SCH772984 multiple interactions EXP 6480464 SCH772984 inhibits the reaction [pachastrissamine analog promotes the reaction [KEAP1 protein binds to SQSTM1 protein]] CTD PMID:35123989 selenium atom increases expression EXP 6480464 Selenium results in increased expression of KEAP1 mRNA CTD PMID:19244175 silibinin multiple interactions ISO Keap1 (Rattus norvegicus) 6480464 Silybin inhibits the reaction [sodium arsenite results in increased expression of KEAP1] CTD PMID:24062023 silicon atom multiple interactions ISO Keap1 (Mus musculus) 6480464 Thioctic Acid inhibits the reaction [Silicon results in increased expression of KEAP1 protein] CTD PMID:34252510 silicon atom increases expression ISO Keap1 (Mus musculus) 6480464 Silicon results in increased expression of KEAP1 protein CTD PMID:34252510 silicon dioxide multiple interactions EXP 6480464 tanshinone promotes the reaction [Silicon Dioxide results in decreased expression of KEAP1 protein] CTD PMID:32097614 silicon dioxide decreases expression EXP 6480464 Silicon Dioxide results in decreased expression of KEAP1 protein CTD PMID:32097614 sirolimus increases expression EXP 6480464 Sirolimus results in increased expression of KEAP1 protein CTD PMID:29781141 sirolimus multiple interactions EXP 6480464 Sirolimus inhibits the reaction [Resveratrol inhibits the reaction [Particulate Matter affects the expression of KEAP1 protein]] CTD PMID:29781141 sodium arsenite multiple interactions EXP 6480464 Decitabine inhibits the reaction [sodium arsenite results in decreased expression of KEAP1 protein] more ... CTD PMID:18417180 more ... sodium arsenite increases methylation EXP 6480464 sodium arsenite results in increased methylation of KEAP1 promoter CTD PMID:26409248 sodium arsenite affects folding ISO Keap1 (Mus musculus) 6480464 sodium arsenite affects the folding of KEAP1 protein CTD PMID:30261176 sodium arsenite decreases expression EXP 6480464 sodium arsenite results in decreased expression of KEAP1 protein CTD PMID:26409248 and PMID:28229933 sodium arsenite affects expression ISO Keap1 (Rattus norvegicus) 6480464 sodium arsenite affects the expression of KEAP1 mRNA CTD PMID:25625412 sodium arsenite increases expression ISO Keap1 (Rattus norvegicus) 6480464 sodium arsenite results in increased expression of KEAP1 CTD PMID:24062023 sodium arsenite multiple interactions ISO Keap1 (Rattus norvegicus) 6480464 silybin inhibits the reaction [sodium arsenite results in increased expression of KEAP1] CTD PMID:24062023 sodium arsenite increases expression ISO Keap1 (Mus musculus) 6480464 sodium arsenite results in increased expression of KEAP1 mRNA and sodium arsenite results in increased expression of KEAP1 protein CTD PMID:26371860 and PMID:35679981 sodium arsenite multiple interactions ISO Keap1 (Mus musculus) 6480464 ATG7 gene mutant form inhibits the reaction [sodium arsenite results in increased degradation of KEAP1 protein] more ... CTD PMID:16785233 more ... sodium arsenite affects localization EXP 6480464 sodium arsenite affects the localization of KEAP1 protein CTD PMID:23589329 sodium dichromate decreases expression ISO Keap1 (Mus musculus) 6480464 sodium bichromate results in decreased expression of KEAP1 mRNA CTD PMID:22155349 sodium fluoride multiple interactions ISO Keap1 (Rattus norvegicus) 6480464 Sodium Selenite inhibits the reaction [Sodium Fluoride results in decreased expression of KEAP1 mRNA] CTD PMID:36736877 sodium fluoride decreases expression ISO Keap1 (Rattus norvegicus) 6480464 Sodium Fluoride results in decreased expression of KEAP1 mRNA CTD PMID:36736877 solanesol multiple interactions EXP 6480464 solanesol inhibits the reaction [Glucose results in increased expression of KEAP1 mRNA] more ... CTD PMID:25645596 and PMID:37586544 sterigmatocystin affects expression ISO Keap1 (Rattus norvegicus) 6480464 Sterigmatocystin affects the expression of KEAP1 mRNA CTD PMID:34126181 streptozocin multiple interactions ISO Keap1 (Rattus norvegicus) 6480464 [Streptozocin co-treated with Niacinamide] results in increased expression of KEAP1 mRNA more ... CTD PMID:21439372 more ... streptozocin increases expression ISO Keap1 (Mus musculus) 6480464 Streptozocin results in increased expression of KEAP1 mRNA CTD PMID:34896238 streptozocin multiple interactions ISO Keap1 (Mus musculus) 6480464 2 more ... CTD PMID:34896238 and PMID:37120126 streptozocin increases expression ISO Keap1 (Rattus norvegicus) 6480464 Streptozocin results in increased expression of KEAP1 mRNA and Streptozocin results in increased expression of KEAP1 protein CTD PMID:32662907 and PMID:33639173 streptozocin decreases expression ISO Keap1 (Rattus norvegicus) 6480464 Streptozocin results in decreased expression of KEAP1 mRNA CTD PMID:30817903 sulforaphane increases expression EXP 6480464 sulforaphane results in increased expression of KEAP1 protein CTD PMID:19033392 sulforaphane decreases expression EXP 6480464 sulforaphane results in decreased expression of KEAP1 mRNA CTD PMID:35724838 sulforaphane decreases response to substance EXP 6480464 KEAP1 protein mutant form results in decreased susceptibility to sulforaphane CTD PMID:23589329 sulforaphane multiple interactions ISO Keap1 (Mus musculus) 6480464 sulforaphane inhibits the reaction [Carbon Tetrachloride results in increased expression of KEAP1 protein] more ... CTD PMID:15865434 more ... sulforaphane multiple interactions ISO Keap1 (Rattus norvegicus) 6480464 sulforaphane promotes the reaction [NFE2L2 protein binds to KEAP1 protein] CTD PMID:22558124 sulforaphane increases response to substance ISO Keap1 (Mus musculus) 6480464 KEAP1 protein results in increased susceptibility to sulforaphane CTD PMID:22558124 sulforaphane increases response to substance EXP 6480464 KEAP1 protein results in increased susceptibility to sulforaphane CTD PMID:22558124 sulforaphane increases metabolic processing EXP 6480464 sulforaphane results in increased metabolism of KEAP1 protein CTD PMID:21391649 sulforaphane multiple interactions EXP 6480464 Iodoacetamide inhibits the reaction [sulforaphane results in increased metabolism of KEAP1 protein] more ... CTD PMID:18417180 more ... sulindac decreases expression ISO Keap1 (Rattus norvegicus) 6480464 Sulindac results in decreased expression of KEAP1 mRNA CTD PMID:24136188 T-2 toxin decreases expression EXP 6480464 T-2 Toxin results in decreased expression of KEAP1 mRNA and T-2 Toxin results in decreased expression of KEAP1 protein CTD PMID:35842139 tangeretin multiple interactions ISO Keap1 (Rattus norvegicus) 6480464 tangeretin inhibits the reaction [9 more ... CTD PMID:24995432 Tanshinone I multiple interactions EXP 6480464 tanshinone promotes the reaction [Silicon Dioxide results in decreased expression of KEAP1 protein] CTD PMID:32097614 temozolomide increases expression EXP 6480464 Temozolomide results in increased expression of KEAP1 mRNA CTD PMID:31758290 tert-butyl hydroperoxide multiple interactions EXP 6480464 Plant Extracts inhibits the reaction [tert-Butylhydroperoxide results in increased expression of KEAP1 protein] and Quercetin inhibits the reaction [tert-Butylhydroperoxide results in increased expression of KEAP1 protein] CTD PMID:27050144 tert-butyl hydroperoxide increases expression EXP 6480464 tert-Butylhydroperoxide results in increased expression of KEAP1 protein CTD PMID:27050144 tetrachloromethane increases expression ISO Keap1 (Mus musculus) 6480464 Carbon Tetrachloride results in increased expression of KEAP1 protein CTD PMID:29964319 tetrachloromethane multiple interactions ISO Keap1 (Mus musculus) 6480464 ginsenoside Rg1 inhibits the reaction [Carbon Tetrachloride results in increased expression of KEAP1 protein] and sulforaphane inhibits the reaction [Carbon Tetrachloride results in increased expression of KEAP1 protein] CTD PMID:29964319 thapsigargin increases expression EXP 6480464 Thapsigargin results in increased expression of KEAP1 protein CTD PMID:27358234 thioacetamide decreases expression ISO Keap1 (Rattus norvegicus) 6480464 Thioacetamide results in decreased expression of KEAP1 mRNA CTD PMID:34492290 thiophenes multiple interactions EXP 6480464 Thiophenes inhibits the reaction [KEAP1 gene mutant form promotes the reaction [lipopolysaccharide and E coli O55-B5 results in increased expression of IL6 mRNA]] CTD PMID:23906629 Tiron multiple interactions ISO Keap1 (Mus musculus) 6480464 1 more ... CTD PMID:33368846 trabectedin increases expression EXP 6480464 Trabectedin results in increased expression of KEAP1 protein CTD PMID:36396105 trans-anethole multiple interactions ISO Keap1 (Rattus norvegicus) 6480464 anethole inhibits the reaction [Isoproterenol results in increased expression of KEAP1 mRNA] and anethole inhibits the reaction [Isoproterenol results in increased expression of KEAP1 protein] CTD PMID:35430261 trans-piceid multiple interactions EXP 6480464 polydatin inhibits the reaction [Hydrogen Peroxide results in increased expression of KEAP1 protein] CTD PMID:31705858 trans-piceid multiple interactions ISO Keap1 (Mus musculus) 6480464 polydatin inhibits the reaction [TSHR protein results in increased expression of KEAP1 protein] CTD PMID:31705858 trans-rhaponticin multiple interactions ISO Keap1 (Rattus norvegicus) 6480464 rhapontin inhibits the reaction [Streptozocin results in increased expression of KEAP1 mRNA] and rhapontin inhibits the reaction [Streptozocin results in increased expression of KEAP1 protein] CTD PMID:32662907 tributylstannane decreases expression ISO Keap1 (Mus musculus) 6480464 tributyltin results in decreased expression of KEAP1 protein CTD PMID:36858641 Tributyltin oxide affects localization EXP 6480464 bis(tri-n-butyltin)oxide affects the localization of KEAP1 protein CTD PMID:21601586 tricetin increases expression EXP 6480464 tricetin results in increased expression of KEAP1 mRNA and tricetin results in increased expression of KEAP1 protein CTD PMID:31176653 trichloroethene multiple interactions ISO Keap1 (Mus musculus) 6480464 sulforaphane inhibits the reaction [Trichloroethylene results in increased expression of KEAP1 mRNA] CTD PMID:32073640 trichloroethene increases expression ISO Keap1 (Rattus norvegicus) 6480464 Trichloroethylene results in increased expression of KEAP1 mRNA CTD PMID:33387578 trichloroethene increases expression ISO Keap1 (Mus musculus) 6480464 Trichloroethylene results in increased expression of KEAP1 mRNA CTD PMID:32073640 trichostatin A affects expression EXP 6480464 trichostatin A affects the expression of KEAP1 mRNA CTD PMID:28542535 trilobatin multiple interactions ISO Keap1 (Rattus norvegicus) 6480464 trilobatin inhibits the reaction [Hydrogen Peroxide results in increased expression of KEAP1 protein] CTD PMID:30104959 Triptolide decreases expression EXP 6480464 triptolide results in decreased expression of KEAP1 protein CTD PMID:30682494 and PMID:36990132 triptonide decreases expression ISO Keap1 (Mus musculus) 6480464 triptonide results in decreased expression of KEAP1 mRNA CTD PMID:33045310 troglitazone multiple interactions EXP 6480464 KEAP1 protein promotes the reaction [troglitazone results in increased susceptibility to arsenic trioxide] CTD PMID:22684020 tyloxapol multiple interactions ISO Keap1 (Mus musculus) 6480464 Escin inhibits the reaction [tyloxapol results in increased expression of KEAP1 protein] and Fenofibrate inhibits the reaction [tyloxapol results in increased expression of KEAP1 protein] CTD PMID:36905866 tyloxapol increases expression ISO Keap1 (Mus musculus) 6480464 tyloxapol results in increased expression of KEAP1 protein CTD PMID:36905866 valdecoxib increases expression ISO Keap1 (Rattus norvegicus) 6480464 valdecoxib results in increased expression of KEAP1 mRNA CTD PMID:24136188 valproic acid decreases expression ISO Keap1 (Mus musculus) 6480464 Valproic Acid results in decreased expression of KEAP1 mRNA CTD PMID:21427059 valproic acid affects expression EXP 6480464 Valproic Acid affects the expression of KEAP1 mRNA CTD PMID:25979313 valproic acid decreases expression EXP 6480464 Valproic Acid results in decreased expression of KEAP1 mRNA CTD PMID:22083351 and PMID:29154799 vitamin D decreases expression EXP 6480464 Vitamin D results in decreased expression of KEAP1 protein CTD PMID:30698894 XAV939 multiple interactions EXP 6480464 [[ascorbate-2-phosphate co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of KEAP1 mRNA and [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of KEAP1 mRNA CTD PMID:34480604 zinc atom multiple interactions ISO Keap1 (Mus musculus) 6480464 4 more ... CTD PMID:15865434 zinc atom affects binding ISO Keap1 (Mus musculus) 6480464 Zinc binds to KEAP1 protein CTD PMID:15865434 zinc dichloride affects folding ISO Keap1 (Mus musculus) 6480464 zinc chloride affects the folding of KEAP1 protein CTD PMID:30261176 zinc dichloride multiple interactions ISO Keap1 (Mus musculus) 6480464 zinc chloride promotes the reaction [KEAP1 protein binds to KEAP1 protein] CTD PMID:30261176 zinc(0) multiple interactions ISO Keap1 (Mus musculus) 6480464 4 more ... CTD PMID:15865434 zinc(0) affects binding ISO Keap1 (Mus musculus) 6480464 Zinc binds to KEAP1 protein CTD PMID:15865434
