CYP1B1 (cytochrome P450, family 1, subfamily B, polypeptide 1)

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Keyword

Gene: CYP1B1 (cytochrome P450, family 1, subfamily B, polypeptide 1) Homo sapiens

Symbol:

CYP1B1

Name:

cytochrome P450, family 1, subfamily B, polypeptide 1

Description:

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The enzyme encoded by this gene localizes to the endoplasmic reticulum and metabolizes procarcinogens such as polycyclic aromatic hydrocarbons and 17beta-estradiol. Mutations in this gene have been associated with primary congenital glaucoma; therefore it is thought that the enzyme also metabolizes a signaling molecule involved in eye development, possibly a steroid. [provided by RefSeq, Jul 2008]

Type:

protein-coding

RefSeq Status:

REVIEWED

Also known as:

aryl hydrocarbon hydroxylase; CP1B; CYPIB1; CYPIB1; cytochrome P450 1B1; cytochrome p450, subfamily 1b, polypeptide 1; cytochrome P450, subfamily I (dioxin-inducible), polypeptide 1 (glaucoma 3, primary infantile); flavoprotein-linked monooxygenase; GLC3A; microsomal monooxygenase; OTTHUMP00000126963; OTTHUMP00000201401; P4501B1; xenobiotic monooxygenase

Orthologs:

Mus musculus : Cyp1b1 (cytochrome P450, family 1, subfamily b, polypeptide 1) MGI
Rattus norvegicus : Cyp1b1 (cytochrome P450, family 1, subfamily b, polypeptide 1)

Latest Assembly:

Human Genome Assembly GRCh37

Position:

Map	Chr	Position	Strand	Source
Human Alternate Assembly CHM1_1	2	38,166,245 - 38,174,823	-	NCBI
Human Genome Assembly HuRef	2	38,034,680 - 38,043,258	-	NCBI
Human Genome Assembly GRCh37	2	38,294,746 - 38,303,323	-	NCBI
Human Genome Assembly Build 36	2	38,148,250 - 38,156,796	-	NCBI
Human Cytogenetic Map	2	p22.2		NCBI
Human Genome Assembly	2	38,206,396 - 38,214,943		NCBI