ADAMTS1 (ADAM metallopeptidase with thrombospondin type 1 motif, 1)

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Keyword

Gene: ADAMTS1 (ADAM metallopeptidase with thrombospondin type 1 motif, 1) Homo sapiens

Symbol:

ADAMTS1

Name:

ADAM metallopeptidase with thrombospondin type 1 motif, 1

Description:

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene contains two disintegrin loops and three C-terminal TS motifs and has anti-angiogenic activity. The expression of this gene may be associated with various inflammatory processes as well as development of cancer cachexia. This gene is likely to be necessary for normal growth, fertility, and organ morphology and function. [provided by RefSeq, Jul 2008]

Type:

protein-coding

RefSeq Status:

REVIEWED

Also known as:

A disintegrin and metalloproteinase with thrombospondin motifs 1; a disintegrin and metalloproteinase with thrombospondin motifs 1 (adamts-1); a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 1; ADAM-TS 1; ADAM-TS1; ADAMTS-1; C3-C5; human metalloproteinase with thrombospondin type 1 motifs; KIAA1346; METH-1; METH1; OTTHUMP00000096354

Orthologs:

Mus musculus : Adamts1 (a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1) MGI
Rattus norvegicus : Adamts1 (ADAM metallopeptidase with thrombospondin type 1 motif, 1)

Latest Assembly:

Human Genome Assembly GRCh37

Position:

Map	Chr	Position	Strand	Source
Human Alternate Assembly CHM1_1	21	18,752,354 - 18,761,478	-	NCBI
Human Genome Assembly HuRef	21	13,613,149 - 13,622,273	-	NCBI
Human Genome Assembly GRCh37	21	28,208,606 - 28,217,728	-	NCBI
Human Genome Assembly Build 36	21	27,130,477 - 27,139,599	-	NCBI
Human Cytogenetic Map	21	q21.2		NCBI
Human Genome Assembly	21	27,130,478 - 27,139,599		NCBI