Gene: CAT (catalase)  Homo sapiens
Symbol: CAT
Name: catalase
Description: This gene encodes catalase, a key antioxidant enzyme in the bodies defense against oxidative stress. Catalase is a heme enzyme that is present in the peroxisome of nearly all aerobic cells. Catalase converts the reactive oxygen species hydrogen peroxide to water and oxygen and thereby mitigates the toxic effects of hydrogen peroxide. Oxidative stress is hypothesized to play a role in the development of many chronic or late-onset diseases such as diabetes, asthma, Alzheimer's disease, systemic lupus erythematosus, rheumatoid arthritis, and cancers. Polymorphisms in this gene have been associated with decreases in catalase activity but, to date, acatalasemia is the only disease known to be caused by this gene. [provided by RefSeq, Oct 2009]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: catalase; MGC138422; MGC138424; OTTHUMP00000041455
Orthologs: Mus musculus : Cat (catalase)  MGI
Rattus norvegicus : Cat (catalase)
Latest Assembly: Human Genome Assembly GRCh37
Position:
MapChrPositionStrandSource
Human Alternate Assembly CHM1_11134,389,135 - 34,422,268+NCBI
Human Genome Assembly HuRef1134,157,829 - 34,190,968+NCBI
Human Genome Assembly GRCh371134,460,472 - 34,493,607+NCBI
Human Genome Assembly Build 361134,417,054 - 34,450,183+NCBI
Human Cytogenetic Map11p13 NCBI
Human Genome Assembly1134,417,053 - 34,450,179 NCBI
Model

Launch Genome Browser (GBrowse) : build 36 (hg18) build 37 (hg19)

Annotation    (Toggle Detail/Summary View)