Gene: IL11 (interleukin 11)  Homo sapiens

Symbol: IL11
Name: interleukin 11
Description: The protein encoded by this gene is a member of the gp130 family of cytokines. These cytokines drive the assembly of multisubunit receptor complexes, all of which contain at least one molecule of the transmembrane signaling receptor IL6ST (gp130). This cytokine is shown to stimulate the T-cell-dependent development of immunoglobulin-producing B cells. It is also found to support the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jun 2012]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: adipogenesis inhibitory factor; AGIF; IL-11; interleukin-11; oprelvekin
Orthologs: Mus musculus : Il11 (interleukin 11)  MGI
Rattus norvegicus : Il11 (interleukin 11)
Latest Assembly: Human Genome Assembly GRCh37
Position:
MapChrPositionStrandSource
Human Alternate Assembly CHM1_11956,028,467 - 56,034,548-NCBI
Human Genome Assembly HuRef1952,197,803 - 52,203,675-NCBI
Human Genome Assembly GRCh371955,875,750 - 55,881,831-NCBI
Human Genome Assembly Build 361960,567,569 - 60,573,626-NCBI
Human Cytogenetic Map19q13.3-q13.4 NCBI
Human Genome Assembly1960,567,568 - 60,573,626 NCBI
Model

Launch Genome Browser (GBrowse) : build 36 (hg18) build 37 (hg19)


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Human Genome Assembly GRCh37)

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on IL11
Entrez Gene
Ensembl Gene
Genome Browser: (hg18) (hg19)
HGNC Report
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 736550
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2013-03-12
Status: ACTIVE