MTOR (mechanistic target of rapamycin (serine/threonine kinase))

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Keyword

Gene: MTOR (mechanistic target of rapamycin (serine/threonine kinase)) Homo sapiens

Symbol:

MTOR

Name:

mechanistic target of rapamycin (serine/threonine kinase)

Description:

The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene. [provided by RefSeq, Sep 2008]

Type:

protein-coding

RefSeq Status:

REVIEWED

Also known as:

FK506 binding protein 12-rapamycin associated protein 1; FK506 binding protein 12-rapamycin associated protein 2; FK506-binding protein 12-rapamycin complex-associated protein 1; FKBP-rapamycin associated protein; FKBP12-rapamycin complex-associated protein 1; FLJ44809; FRAP; FRAP1; FRAP2; mammalian target of rapamycin; OTTHUMP00000001983; RAFT1; rapamycin and FKBP12 target 1; rapamycin associated protein FRAP2; rapamycin target protein 1; RAPT1; serine/threonine-protein kinase mTOR

Orthologs:

Mus musculus : Mtor (mechanistic target of rapamycin (serine/threonine kinase)) MGI
Rattus norvegicus : Mtor (mechanistic target of rapamycin (serine/threonine kinase))

Latest Assembly:

Human Genome Assembly GRCh37

Position:

Map	Chr	Position	Strand	Source
Human Alternate Assembly CHM1_1	1	11,185,381 - 11,341,384	-	NCBI
Human Genome Assembly HuRef	1	10,317,883 - 10,473,910	-	NCBI
Human Genome Assembly GRCh37	1	11,166,588 - 11,322,608	-	NCBI
Human Genome Assembly Build 36	1	11,089,179 - 11,245,153	-	NCBI
Human Cytogenetic Map	1	p36.2		NCBI
Human Genome Assembly	1	11,100,857 - 11,256,830		NCBI