KRT80 (keratin 80) - Rat Genome Database

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Keyword

Gene: KRT80 (keratin 80) Homo sapiens

Symbol:

KRT80

Name:

keratin 80

Description:

Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into epithelial keratins and hair keratins. This gene's expression profile shows that it encodes a type II epithelial keratin, although structurally the encoded protein is more like a type II hair keratin. This protein is involved in cell differentiation, localizing near desmosomal plaques in earlier stages of differentiation but then dispersing throughout the cytoplasm in terminally differentiating cells. The type II keratins are clustered in a region of chromosome 12q13. Two transcript variants encoding two different fully functional isoforms have been found for this gene.[provided by RefSeq, Oct 2010]

Type:

protein-coding

RefSeq Status:

REVIEWED

Also known as:

CK-80; cytokeratin-80; K80; KB20; keratin b20; keratin, type II cytoskeletal 80; keratin-80; OTTHUMP00000196565; OTTHUMP00000196566; type II keratin; type-II keratin Kb20

Orthologs:

Mus musculus : Krt80 (keratin 80) MGI
Rattus norvegicus : Krt80 (keratin 80)

Latest Assembly:

Human Genome Assembly GRCh37

Position:

Map	Chr	Position	Strand	Source
Human Alternate Assembly CHM1_1	12	52,396,907 - 52,419,906	-	NCBI
Human Genome Assembly HuRef	12	49,596,065 - 49,619,064	-	NCBI
Human Genome Assembly GRCh37	12	52,562,780 - 52,585,784	-	NCBI
Human Celera Assembly	12	51,365,224 - 51,388,227	-	NCBI
Human Genome Assembly Build 36	12	50,849,047 - 50,872,051	-	NCBI
Human Cytogenetic Map	12	q13.13		NCBI