BAG2 (BCL2-associated athanogene 2)

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Keyword

Gene: BAG2 (BCL2-associated athanogene 2) Homo sapiens

Symbol:

BAG2

Name:

BCL2-associated athanogene 2

Description:

BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. [provided by RefSeq, Jul 2008]

Type:

protein-coding

RefSeq Status:

REVIEWED

Also known as:

BAG family molecular chaperone regulator 2; BAG-2; BAG-family molecular chaperone regulator-2; bcl-2-associated athanogene 2; dJ417I1.2; dJ417I1.2 (BAG-family molecular chaperone regulator 2); KIAA0576; MGC149462; OTTHUMP00000016668

Orthologs:

Mus musculus : Bag2 (BCL2-associated athanogene 2) MGI
Rattus norvegicus : Bag2 (Bcl2-associated athanogene 2)

Latest Assembly:

Human Genome Assembly GRCh37

Position:

Map	Chr	Position	Strand	Source
Human Alternate Assembly CHM1_1	6	56,939,906 - 56,952,817	+	NCBI
Human Genome Assembly HuRef	6	56,871,161 - 56,884,070	+	NCBI
Human Genome Assembly GRCh37	6	57,037,104 - 57,050,013	+	NCBI
Human Celera Assembly	6	58,700,203 - 58,713,112	+	NCBI
Human Genome Assembly Build 36	6	57,145,293 - 57,157,694	+	NCBI
Human Cytogenetic Map	6	p12.1-p11.2		NCBI
Human Genome Assembly	6	57,145,292 - 57,157,692		NCBI