SELE (selectin E) - Rat Genome Database

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Keyword

Gene: SELE (selectin E) Homo sapiens

Symbol:

SELE

Name:

selectin E

Description:

The protein encoded by this gene is found in cytokine-stimulated endothelial cells and is thought to be responsible for the accumulation of blood leukocytes at sites of inflammation by mediating the adhesion of cells to the vascular lining. It exhibits structural features such as the presence of lectin- and EGF-like domains followed by short consensus repeat (SCR) domains that contain 6 conserved cysteine residues. These proteins are part of the selectin family of cell adhesion molecules. Adhesion molecules participate in the interaction between leukocytes and the endothelium and appear to be involved in the pathogenesis of atherosclerosis. [provided by RefSeq, Jul 2008]

Type:

protein-coding

RefSeq Status:

REVIEWED

Also known as:

CD62 antigen-like family member E; CD62E; E-selectin; ELAM; ELAM-1; ELAM1; endothelial adhesion molecule 1; endothelial leukocyte adhesion molecule 1; ESEL; LECAM2; leukocyte endothelial cell adhesion molecule 2; leukocyte-endothelial cell adhesion molecule 2; OTTHUMP00000032745; OTTHUMP00000032746; OTTHUMP00000032747; OTTHUMP00000032748; OTTHUMP00000032749

Orthologs:

Mus musculus : Sele (selectin, endothelial cell) MGI
Rattus norvegicus : Sele (selectin E)

Latest Assembly:

Human Genome Assembly GRCh37

Position:

Map	Chr	Position	Strand	Source
Human Alternate Assembly CHM1_1	1	176,244,235 - 176,255,673	-	NCBI
Human Genome Assembly HuRef	1	140,914,126 - 140,925,551	-	NCBI
Human Genome Assembly GRCh37	1	169,691,781 - 169,703,220	-	NCBI
Human Genome Assembly Build 36	1	167,958,406 - 167,969,803	-	NCBI
Human Cytogenetic Map	1	q22-q25		NCBI
Human Genome Assembly	1	166,423,439 - 166,434,837		NCBI