PTK2 (protein tyrosine kinase 2) - Rat Genome Database

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Keyword

Gene: PTK2 (protein tyrosine kinase 2) Homo sapiens

Symbol:

PTK2

Name:

protein tyrosine kinase 2

Description:

This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene, but the full-length natures of only three of them have been determined. [provided by RefSeq, Dec 2010]

Type:

protein-coding

RefSeq Status:

REVIEWED

Also known as:

FADK; FADK 1; FAK; FAK-related non-kinase polypeptide; FAK1; focal adhesion kinase 1; focal adhesion kinase-related nonkinase; FRNK; OTTHUMP00000226318; OTTHUMP00000226320; OTTHUMP00000226325; OTTHUMP00000226326; OTTHUMP00000226333; OTTHUMP00000226334; OTTHUMP00000226350; OTTHUMP00000226586; p125FAK; pp125FAK; PPP1R71; protein phosphatase 1 regulatory subunit 71; protein phosphatase 1, regulatory subunit 71; protein tyrosine kinase 2; protein-tyrosine kinase 2; PTK2 protein tyrosine kinase 2

Orthologs:

Mus musculus : Ptk2 (PTK2 protein tyrosine kinase 2) MGI
Rattus norvegicus : Ptk2 (protein tyrosine kinase 2)

Latest Assembly:

Human Genome Assembly GRCh37

Position:

Map	Chr	Position	Strand	Source
Human Alternate Assembly CHM1_1	8	141,940,281 - 142,283,082	-	NCBI
Human Genome Assembly HuRef	8	136,979,065 - 137,322,195	-	NCBI
Human Genome Assembly GRCh37	8	141,668,481 - 142,011,412	-	NCBI
Human Genome Assembly Build 36	8	141,737,683 - 142,080,514	-	NCBI
Human Cytogenetic Map	8	q24.3		NCBI
Human Genome Assembly	8	141,737,682 - 142,080,514		NCBI