Gene: MYC (v-myc myelocytomatosis viral oncogene homolog (avian))  Homo sapiens
Symbol: MYC
Name: v-myc myelocytomatosis viral oncogene homolog (avian)
Description: The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: avian myelocytomatosis viral oncogene homolog; bHLHe39; c-Myc; class E basic helix-loop-helix protein 39; MRTL; myc proto-oncogene protein; myc-related translation/localization regulatory factor; OTTHUMP00000158589; OTTHUMP00000227763; proto-oncogene c-Myc; transcription factor p64; v-myc avian myelocytomatosis viral oncogene homolog
Orthologs: Mus musculus : Myc (myelocytomatosis oncogene)  MGI
Rattus norvegicus : Myc (myelocytomatosis oncogene)
Latest Assembly: Human Genome Assembly GRCh37
Position:
MapChrPositionStrandSource
Human Alternate Assembly CHM1_18129,009,532 - 129,014,897+NCBI
Human Genome Assembly HuRef8124,069,829 - 124,075,195+NCBI
Human Genome Assembly GRCh378128,748,315 - 128,753,680+NCBI
Human Genome Assembly Build 368128,817,498 - 128,822,856+NCBI
Human Cytogenetic Map8q24.21 NCBI
Human Genome Assembly8128,817,685 - 128,822,853 NCBI
Model

Launch Genome Browser (GBrowse) : build 36 (hg18) build 37 (hg19)

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