TIMP3 (TIMP metallopeptidase inhibitor 3)

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Keyword

Gene: TIMP3 (TIMP metallopeptidase inhibitor 3) Homo sapiens

Symbol:

TIMP3

Name:

TIMP metallopeptidase inhibitor 3

Description:

This gene belongs to the TIMP gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix (ECM). Expression of this gene is induced in response to mitogenic stimulation and this netrin domain-containing protein is localized to the ECM. Mutations in this gene have been associated with the autosomal dominant disorder Sorsby's fundus dystrophy. [provided by RefSeq, Jul 2008]

Type:

protein-coding

RefSeq Status:

REVIEWED

Also known as:

HSMRK222; K222; K222TA2; metalloproteinase inhibitor 3; MIG-5 protein; OTTHUMP00000028880; OTTHUMP00000064008; protein MIG-5; SFD; TIMP metallopeptidase inhibitor 3 (Sorsby fundus dystrophy, pseudoinflammatory); TIMP-3; tissue inhibitor of metalloproteinase 3; tissue inhibitor of metalloproteinases 3

Orthologs:

Mus musculus : Timp3 (tissue inhibitor of metalloproteinase 3) MGI
Rattus norvegicus : Timp3 (TIMP metallopeptidase inhibitor 3)

Latest Assembly:

Human Genome Assembly GRCh37

Position:

Map	Chr	Position	Strand	Source
Human Alternate Assembly CHM1_1	22	17,118,505 - 17,180,728	+	NCBI
Human Genome Assembly HuRef	22	16,154,700 - 16,216,984	+	NCBI
Human Genome Assembly GRCh37	22	33,196,802 - 33,259,028	+	NCBI
Human Genome Assembly Build 36	22	31,526,802 - 31,589,028	+	NCBI
Human Cytogenetic Map	22	q12.3		ENTREZGENE
Human Genome Assembly	22	31,521,361 - 31,583,581		NCBI